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  * Biological use case

International Conference on Systems Biology Demos

Description

This is an internal wiki page for collecting abstracts, data, posters, and other materials for the arena demos on Cytoscape at the International Conference on Systems Biology.

Facts on the conference and demos

  • Started 2000 by Kitano, now organized by ISSB
  • Lots of big names in bioinformatics
  • Cytoscape will have an arena (booth) in the conference exhibition/poster area
  • web site: http://www.icsb-2008.org

  • Arena hours: Three days: Sun Aug 24th – Tue 26th
    • Aug 24 1300-1600 and 1800-2000
    • Aug 25 1300-1500
    • Aug 26 1300-1600 and 1800-200
    • 5-10 workflows using plugins

Setup for plugin abstracts

  • Short abstract
  • Analysis keywords
  • Cytoscape keywords
  • Sample and info on wiki page…

Setup for workflow recipes

  • Required
    • Biological use case
    • Scripted recipe describing data, plugins, cytoscape version, GUI steps to take to demo
    • Datafiles
    • Presentation (ppt)
  • Suggested
    • Out of the box webstart...
    • Video (Allan; can you add sites discussed with Gang?)

Map of Plugins to Scenarios

Network Context

Biological Use Case

Plugins used(abstracts)

Guidelines/Recipes

Remarks

Annotate network

Overlay Gene Expression Data on Network

jActiveModules?

NatureProtocolsDemo

Need to get full list of plugins for this

Expand network

Predict molecular interactions

MiMiPlugin

TBD

talk with David States about this

Find active regions

Find probable targets in cardiovascular disease

TBD

AtheroSclerosisDemo

Infer gene targets for wetlab testing

R2Plugin, BiNGO

R2InferGeneTargetsRecipe

R2AndCytoscape is good example of how easy it is to write plugins.

Find possible complexes, protein families, functional relationships epistatic mapping??

Mcode, CyOogGraphLayout, CommunityStructureLayout

McodePluginDemo, ClusterMakerDemo

get epistatic map network from Scooter, break it into a separate use scenario?

Multi-level Network Analysis

Which splice variants influence the structure of ppi networks

DomainGraph, NetworkAnalyzer

DomainGraphRecipe

Expand the network by incorporating lower level structure and function

plugins?

StructureVizChimera

will require some familiarization with Chimera. Perhaps hook up with SubGeneViewer (splice variation to domain)? Side benefit is to show how plugins written completely independently can interoperate with each other to answer a biological question.

Pathway Curation, Storing and Exporting Images

Storing and expanding knowledge of biological networks

WikiPathways

WikiPathwaysPathVisio

To Do

Plugin / Scenario

Who

Abstract

Data

Webstart

Script

Video

Comments

AtheroSclerosisDemo

AllanK

done

R2AndCytoscape

Piet

done

StructureVizChimera

Scooter

ClusterMakerDemo

Scooter

McodePluginDemo

Gary

MiMiPluginDemo

David, Jing

done

NatureProtocolsDemo

AllanK

WikiPathwaysPathVisio

Thomas

done

CyOogGraphLayout

Matthias

DomainGraph

Dorothea

done

NetworkAnalyzer

Mario

done

CommunityStructureLayout

Gang

SubGeneViewerDemo

Alex, AllanK

WodakLabDemos

Shoshana

Data

put data files here

Posters

put posters here

Other stuff

Posters from ISMB

Notes

ask about GenePro, validation to gold standard, pie nodes (U toronto)

also Brian Turner's metabolomics work (same research group, Shoshana Wodak's)

we will also be receiving a video from Alitora (http://alitora.com/index.html) about their semantic web plugin for Cytoscape.

InternationalConferenceOnSystemsBiologyDemos (last edited 2009-02-12 01:03:58 by localhost)

Funding for Cytoscape is provided by a federal grant from the U.S. National Institute of General Medical Sciences (NIGMS) of the Na tional Institutes of Health (NIH) under award number GM070743-01. Corporate funding is provided through a contract from Unilever PLC.

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