Attachment 'EC_iJR904.xml'
Download 1 <?xml version="1.0" encoding="UTF-8"?>
2 <sbml xmlns="http://www.sbml.org/sbml/level2" level="2" version="1" xmlns:html="http://www.w3.org/1999/xhtml">
3 <model id="Ec_iJR904" name="Ec_iJR904">
4 <listOfCompartments>
5 <compartment id="Extra_organism"/>
6 <compartment id="Cytosol" outside="Extra_organism"/>
7 </listOfCompartments>
8 <listOfSpecies>
9 <species id="M_10fthf_c" name="M_10_Formyltetrahydrofolate_C20H21N7O7" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
10 <species id="M_12dgr_EC_c" name="M_1_2_Diacylglycerol___Ecoli__C1836H3448O250" compartment="Cytosol" charge="0" boundaryCondition="false"/>
11 <species id="M_12ppd_S_c" name="M__S__Propane_1_2_diol_C3H8O2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
12 <species id="M_12ppd_S_e" name="M__S__Propane_1_2_diol_C3H8O2" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
13 <species id="M_13dpg_c" name="M_3_Phospho_D_glyceroyl_phosphate_C3H4O10P2" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
14 <species id="M_15dap_c" name="M_1_5_Diaminopentane_C5H16N2" compartment="Cytosol" charge="2" boundaryCondition="false"/>
15 <species id="M_15dap_e" name="M_1_5_Diaminopentane_C5H16N2" compartment="Extra_organism" charge="2" boundaryCondition="false"/>
16 <species id="M_1pyr5c_c" name="M_1_Pyrroline_5_carboxylate_C5H6NO2" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
17 <species id="M_23ddhb_c" name="M_2_3_Dihydro_2_3_dihydroxybenzoate_C7H7O4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
18 <species id="M_23dhb_c" name="M_2_3_Dihydroxybenzoate_C7H5O4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
19 <species id="M_23dhba_c" name="M__2_3_Dihydroxybenzoyl_adenylate_C17H16N5O10P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
20 <species id="M_23dhdp_c" name="M_2_3_Dihydrodipicolinate_C7H5NO4" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
21 <species id="M_23dhmb_c" name="M__R__2_3_Dihydroxy_3_methylbutanoate_C5H9O4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
22 <species id="M_23dhmp_c" name="M__R__2_3_Dihydroxy_3_methylpentanoate_C6H11O4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
23 <species id="M_23doguln_c" name="M_2_3_Dioxo_L_gulonate_C6H7O7" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
24 <species id="M_25aics_c" name="M__S__2_5_Amino_1__5_phospho_D_ribosyl_imidazole_4_carboxamidosuccinate_C13H15N4O12P" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
25 <species id="M_25dkglcn_c" name="M_2_5_diketo_D_gluconate_C6H7O7" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
26 <species id="M_25drapp_c" name="M_2_5_Diamino_6__ribosylamino__4__3H__pyrimidinone_5__phosphate_C9H14N5O8P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
27 <species id="M_26dap_LL_c" name="M_LL_2_6_Diaminoheptanedioate_C7H14N2O4" compartment="Cytosol" charge="0" boundaryCondition="false"/>
28 <species id="M_26dap_M_c" name="M_meso_2_6_Diaminoheptanedioate_C7H14N2O4" compartment="Cytosol" charge="0" boundaryCondition="false"/>
29 <species id="M_26dap_M_e" name="M_meso_2_6_Diaminoheptanedioate_C7H14N2O4" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
30 <species id="M_2ahbut_c" name="M__S__2_Aceto_2_hydroxybutanoate_C6H9O4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
31 <species id="M_2aobut_c" name="M_L_2_Amino_3_oxobutanoate_C4H7NO3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
32 <species id="M_2cpr5p_c" name="M_1__2_Carboxyphenylamino__1_deoxy_D_ribulose_5_phosphate_C12H13NO9P" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
33 <species id="M_2dda7p_c" name="M_2_Dehydro_3_deoxy_D_arabino_heptonate_7_phosphate_C7H10O10P" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
34 <species id="M_2ddg6p_c" name="M_2_Dehydro_3_deoxy_D_gluconate_6_phosphate_C6H8O9P" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
35 <species id="M_2ddglcn_c" name="M_2_Dehydro_3_deoxy_D_gluconate_C6H9O6" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
36 <species id="M_2ddglcn_e" name="M_2_Dehydro_3_deoxy_D_gluconate_C6H9O6" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
37 <species id="M_2dh3dgal6p_c" name="M_2_Dehydro_3_deoxy_D_galactonate_6_phosphate_C6H8O9P" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
38 <species id="M_2dh3dgal_c" name="M_2_Dehydro_3_deoxy_D_galactonate_C6H9O6" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
39 <species id="M_2dhglcn_c" name="M_2_Dehydro_D_gluconate_C6H9O7" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
40 <species id="M_2dhguln_c" name="M_2_Dehydro_L_gulonate_C6H9O7" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
41 <species id="M_2dhp_c" name="M_2_Dehydropantoate_C6H9O4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
42 <species id="M_2dmmq8_c" name="M_2_Demethylmenaquinone_8_C50H70O2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
43 <species id="M_2dmmql8_c" name="M_2_Demethylmenaquinol_8_C50H72O2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
44 <species id="M_2dr1p_c" name="M_2_Deoxy_D_ribose_1_phosphate_C5H9O7P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
45 <species id="M_2dr5p_c" name="M_2_Deoxy_D_ribose_5_phosphate_C5H9O7P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
46 <species id="M_2h3oppan_c" name="M_2_Hydroxy_3_oxopropanoate_C3H3O4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
47 <species id="M_2ippm_c" name="M_2_Isopropylmaleate_C7H8O4" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
48 <species id="M_2kmb_c" name="M_2_keto_4_methylthiobutyrate_C5H7O3S" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
49 <species id="M_2mahmp_c" name="M_2_Methyl_4_amino_5_hydroxymethylpyrimidine_diphosphate_C6H8N3O7P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
50 <species id="M_2mcacn_c" name="M_cis_2_Methylaconitate_C7H5O6" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
51 <species id="M_2mcit_c" name="M_2_Methylcitrate_C7H7O7" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
52 <species id="M_2me4p_c" name="M_2_C_methyl_D_erythritol_4_phosphate_C5H11O7P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
53 <species id="M_2mecdp_c" name="M_2_C_methyl_D_erythritol_2_4_cyclodiphosphate_C5H10O9P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
54 <species id="M_2obut_c" name="M_2_Oxobutanoate_C4H5O3" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
55 <species id="M_2ohph_c" name="M_2_Octaprenyl_6_hydroxyphenol_C46H70O2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
56 <species id="M_2ombzl_c" name="M_2_Octaprenyl_6_methoxy_1_4_benzoquinol_C47H72O3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
57 <species id="M_2omhmbl_c" name="M_2_Octaprenyl_3_methyl_5_hydroxy_6_methoxy_1_4_benzoquinol_C48H74O4" compartment="Cytosol" charge="0" boundaryCondition="false"/>
58 <species id="M_2ommbl_c" name="M_2_Octaprenyl_3_methyl_6_methoxy__1_4_benzoquinol_C48H74O3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
59 <species id="M_2omph_c" name="M_2_Octaprenyl_6_methoxyphenol_C47H72O2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
60 <species id="M_2oph_c" name="M_2_Octaprenylphenol_C46H70O" compartment="Cytosol" charge="0" boundaryCondition="false"/>
61 <species id="M_2p4c2me_c" name="M_2_phospho_4__cytidine_5__diphospho__2_C_methyl_D_erythritol_C14H22N3O17P3" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
62 <species id="M_2pg_c" name="M_D_Glycerate_2_phosphate_C3H4O7P" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
63 <species id="M_2pglyc_c" name="M_2_Phosphoglycolate_C2H2O6P" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
64 <species id="M_2shchc_c" name="M_2_Succinyl_6_hydroxy_2_4_cyclohexadiene_1_carboxylate_C11H10O6" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
65 <species id="M_34hpp_c" name="M_3__4_Hydroxyphenyl_pyruvate_C9H7O4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
66 <species id="M_3c2hmp_c" name="M_3_Carboxy_2_hydroxy_4_methylpentanoate_C7H10O5" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
67 <species id="M_3c3hmp_c" name="M_3_Carboxy_3_hydroxy_4_methylpentanoate_C7H10O5" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
68 <species id="M_3c4mop_c" name="M_3_Carboxy_4_methyl_2_oxopentanoate_C7H8O5" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
69 <species id="M_3dhguln_c" name="M_3_Dehydro_L_gulonate_C6H9O7" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
70 <species id="M_3dhgulnp_c" name="M_3_keto_L_gulonate_6_phosphate_C6H8O10P" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
71 <species id="M_3dhq_c" name="M_3_Dehydroquinate_C7H9O6" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
72 <species id="M_3dhsk_c" name="M_3_Dehydroshikimate_C7H7O5" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
73 <species id="M_3hcinnm_c" name="M_3_hydroxycinnamic_acid_C9H7O3" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
74 <species id="M_3hcinnm_e" name="M_3_hydroxycinnamic_acid_C9H7O3" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
75 <species id="M_3hmrsACP_c" name="M__R__3_Hydroxytetradecanoyl_acyl_carrier_protein_C25H47N2O9PRS" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
76 <species id="M_3hpppn_c" name="M_3__3_hydroxy_phenyl_propionate_C9H9O3" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
77 <species id="M_3hpppn_e" name="M_3__3_hydroxy_phenyl_propionate_C9H9O3" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
78 <species id="M_3ig3p_c" name="M_C___3_Indolyl__glycerol_3_phosphate_C11H12NO6P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
79 <species id="M_3mob_c" name="M_3_Methyl_2_oxobutanoate_C5H7O3" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
80 <species id="M_3mop_c" name="M__S__3_Methyl_2_oxopentanoate_C6H9O3" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
81 <species id="M_3ophb_c" name="M_3_Octaprenyl_4_hydroxybenzoate_C47H69O3" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
82 <species id="M_3pg_c" name="M_3_Phospho_D_glycerate_C3H4O7P" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
83 <species id="M_3php_c" name="M_3_Phosphohydroxypyruvate_C3H2O7P" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
84 <species id="M_3psme_c" name="M_5_O__1_Carboxyvinyl__3_phosphoshikimate_C10H9O10P" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
85 <species id="M_4abut_c" name="M_4_Aminobutanoate_C4H9NO2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
86 <species id="M_4abut_e" name="M_4_Aminobutanoate_C4H9NO2" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
87 <species id="M_4abutn_c" name="M_4_Aminobutanal_C4H10NO" compartment="Cytosol" charge="1" boundaryCondition="false"/>
88 <species id="M_4abz_c" name="M_4_Aminobenzoate_C7H6NO2" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
89 <species id="M_4adcho_c" name="M_4_amino_4_deoxychorismate_C10H10NO5" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
90 <species id="M_4ahmmp_c" name="M_4_Amino_5_hydroxymethyl_2_methylpyrimidine_C6H9N3O" compartment="Cytosol" charge="0" boundaryCondition="false"/>
91 <species id="M_4ampm_c" name="M_4_Amino_2_methyl_5_phosphomethylpyrimidine_C6H8N3O4P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
92 <species id="M_4c2me_c" name="M_4__cytidine_5__diphospho__2_C_methyl_D_erythritol_C14H23N3O14P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
93 <species id="M_4h2opntn_c" name="M_4_Hydroxy_2_oxopentanoate_C5H7O4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
94 <species id="M_4hba_c" name="M_4_Hydroxy_benzyl_alcohol_C7H8O2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
95 <species id="M_4hbz_c" name="M_4_Hydroxybenzoate_C7H5O3" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
96 <species id="M_4hthr_c" name="M_4_Hydroxy_L_threonine_C4H9NO4" compartment="Cytosol" charge="0" boundaryCondition="false"/>
97 <species id="M_4mhetz_c" name="M_4_Methyl_5__2_hydroxyethyl__thiazole_C6H9NOS" compartment="Cytosol" charge="0" boundaryCondition="false"/>
98 <species id="M_4mop_c" name="M_4_Methyl_2_oxopentanoate_C6H9O3" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
99 <species id="M_4mpetz_c" name="M_4_Methyl_5__2_phosphoethyl__thiazole_C6H8NO4PS" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
100 <species id="M_4pasp_c" name="M_4_Phospho_L_aspartate_C4H6NO7P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
101 <species id="M_4per_c" name="M_4_Phospho_D_erythronate_C4H6O8P" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
102 <species id="M_4ppan_c" name="M_D_4__Phosphopantothenate_C9H15NO8P" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
103 <species id="M_4ppcys_c" name="M_N___R__4_Phosphopantothenoyl__L_cysteine_C12H20N2O9PS" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
104 <species id="M_4r5au_c" name="M_4__1_D_Ribitylamino__5_aminouracil_C9H16N4O6" compartment="Cytosol" charge="0" boundaryCondition="false"/>
105 <species id="M_5aizc_c" name="M_5_amino_1__5_phospho_D_ribosyl_imidazole_4_carboxylate_C9H11N3O9P" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
106 <species id="M_5aop_c" name="M_5_Amino_4_oxopentanoate_C5H9NO3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
107 <species id="M_5aprbu_c" name="M_5_Amino_6__5__phosphoribitylamino_uracil_C9H15N4O9P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
108 <species id="M_5apru_c" name="M_5_Amino_6__5__phosphoribosylamino_uracil_C9H13N4O9P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
109 <species id="M_5caiz_c" name="M_5_phosphoribosyl_5_carboxyaminoimidazole_C9H11N3O9P" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
110 <species id="M_5dglcn_c" name="M_5_Dehydro_D_gluconate_C6H9O7" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
111 <species id="M_5dh4dglc_c" name="M_5_Dehydro_4_deoxy_D_glucarate_C6H6O7" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
112 <species id="M_5mdr1p_c" name="M_5_Methylthio_5_deoxy_D_ribose_1_phosphate_C6H11O7PS" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
113 <species id="M_5mdru1p_c" name="M_5_Methylthio_5_deoxy_D_ribulose_1_phosphate_C6H11O7PS" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
114 <species id="M_5mta_c" name="M_5_Methylthioadenosine_C11H15N5O3S" compartment="Cytosol" charge="0" boundaryCondition="false"/>
115 <species id="M_5mthf_c" name="M_5_Methyltetrahydrofolate_C20H24N7O6" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
116 <species id="M_5mtr_c" name="M_5_Methylthio_D_ribose_C6H12O4S" compartment="Cytosol" charge="0" boundaryCondition="false"/>
117 <species id="M_5prdmbz_c" name="M_N1__5_Phospho_alpha_D_ribosyl__5_6_dimethylbenzimidazole_C14H17N2O7P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
118 <species id="M_6hmhpt_c" name="M_6_hydroxymethyl_dihydropterin_C7H9N5O2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
119 <species id="M_6hmhptpp_c" name="M_6_hydroxymethyl_dihydropterin_pyrophosphate_C7H8N5O8P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
120 <species id="M_6pgc_c" name="M_6_Phospho_D_gluconate_C6H10O10P" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
121 <species id="M_6pgl_c" name="M_6_phospho_D_glucono_1_5_lactone_C6H9O9P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
122 <species id="M_8aonn_c" name="M_8_Amino_7_oxononanoate_C9H17NO3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
123 <species id="M_ACP_c" name="M_acyl_carrier_protein_C11H21N2O7PRS" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
124 <species id="M_N1aspmd_c" name="M_N1_Acetylspermidine_C9H23N3O" compartment="Cytosol" charge="2" boundaryCondition="false"/>
125 <species id="M_aacald_c" name="M_Aminoacetaldehyde_C2H6NO" compartment="Cytosol" charge="1" boundaryCondition="false"/>
126 <species id="M_aacoa_c" name="M_Acetoacetyl_CoA_C25H36N7O18P3S" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
127 <species id="M_acACP_c" name="M_Acetyl_ACP_C13H23N2O8PRS" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
128 <species id="M_ac_c" name="M_Acetate_C2H3O2" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
129 <species id="M_ac_e" name="M_Acetate_C2H3O2" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
130 <species id="M_acac_c" name="M_Acetoacetate_C4H5O3" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
131 <species id="M_acac_e" name="M_Acetoacetate_C4H5O3" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
132 <species id="M_acald_c" name="M_Acetaldehyde_C2H4O" compartment="Cytosol" charge="0" boundaryCondition="false"/>
133 <species id="M_acald_e" name="M_Acetaldehyde_C2H4O" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
134 <species id="M_accoa_c" name="M_Acetyl_CoA_C23H34N7O17P3S" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
135 <species id="M_acg5p_c" name="M_N_Acetyl_L_glutamyl_5_phosphate_C7H9NO8P" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
136 <species id="M_acg5sa_c" name="M_N_Acetyl_L_glutamate_5_semialdehyde_C7H10NO4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
137 <species id="M_acgam1p_c" name="M_N_Acetyl_D_glucosamine_1_phosphate_C8H14NO9P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
138 <species id="M_acgam6p_c" name="M_N_Acetyl_D_glucosamine_6_phosphate_C8H14NO9P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
139 <species id="M_acgam_e" name="M_N_Acetyl_D_glucosamine_C8H15NO6" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
140 <species id="M_acglu_c" name="M_N_Acetyl_L_glutamate_C7H9NO5" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
141 <species id="M_acmana_c" name="M_N_Acetyl_D_mannosamine_C8H15NO6" compartment="Cytosol" charge="0" boundaryCondition="false"/>
142 <species id="M_acmana_e" name="M_N_Acetyl_D_mannosamine_C8H15NO6" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
143 <species id="M_acmanap_c" name="M_N_Acetyl_D_mannosamine_6_phosphate_C8H14NO9P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
144 <species id="M_acnam_c" name="M_N_Acetylneuraminate_C11H18NO9" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
145 <species id="M_acnam_e" name="M_N_Acetylneuraminate_C11H18NO9" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
146 <species id="M_acon_T_c" name="M_trans_Aconitate_C6H3O6" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
147 <species id="M_aconm_c" name="M_E_3_carboxy_2_pentenedioate_6_methyl_ester_C7H6O6" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
148 <species id="M_acorn_c" name="M_N2_Acetyl_L_ornithine_C7H14N2O3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
149 <species id="M_acser_c" name="M_O_Acetyl_L_serine_C5H9NO4" compartment="Cytosol" charge="0" boundaryCondition="false"/>
150 <species id="M_actACP_c" name="M_Acetoacetyl_ACP_C15H25N2O9PRS" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
151 <species id="M_actp_c" name="M_Acetyl_phosphate_C2H3O5P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
152 <species id="M_ade_c" name="M_Adenine_C5H5N5" compartment="Cytosol" charge="0" boundaryCondition="false"/>
153 <species id="M_ade_e" name="M_Adenine_C5H5N5" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
154 <species id="M_adn_c" name="M_Adenosine_C10H13N5O4" compartment="Cytosol" charge="0" boundaryCondition="false"/>
155 <species id="M_adn_e" name="M_Adenosine_C10H13N5O4" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
156 <species id="M_adocbi_c" name="M_Adenosyl_cobinamide_C58H84CoN16O11" compartment="Cytosol" charge="1" boundaryCondition="false"/>
157 <species id="M_adocbip_c" name="M_Adenosyl_cobinamide_phosphate_C58H83CoN16O14P" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
158 <species id="M_adocbl_c" name="M_Adenosylcobalamin_C72H100CoN18O17P" compartment="Cytosol" charge="0" boundaryCondition="false"/>
159 <species id="M_adp_c" name="M_ADP_C10H12N5O10P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
160 <species id="M_adpglc_c" name="M_ADPglucose_C16H23N5O15P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
161 <species id="M_adphep_DD_c" name="M_ADP_D_glycero_D_manno_heptose_C17H25N5O16P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
162 <species id="M_adphep_LD_c" name="M_ADP_L_glycero_D_manno_heptose_C17H25N5O16P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
163 <species id="M_agdpcbi_c" name="M_Adenosine_GDP_cobinamide_C68H95CoN21O21P2" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
164 <species id="M_agm_c" name="M_Agmatine_C5H16N4" compartment="Cytosol" charge="2" boundaryCondition="false"/>
165 <species id="M_agpc_EC_c" name="M_acyl_glycerophosphocholine_C1243H2524N50O350P50" compartment="Cytosol" charge="0" boundaryCondition="false"/>
166 <species id="M_agpe_EC_c" name="M_acyl_glycerophosphoethanolamine___Ecoli__C1093H2224O350N50P50" compartment="Cytosol" charge="0" boundaryCondition="false"/>
167 <species id="M_agpg_EC_c" name="M_acyl_glycerophosphoglycerol___Ecoli__C1143H2224O450P50" compartment="Cytosol" charge="-50" boundaryCondition="false"/>
168 <species id="M_ahcys_c" name="M_S_Adenosyl_L_homocysteine_C14H20N6O5S" compartment="Cytosol" charge="0" boundaryCondition="false"/>
169 <species id="M_ahdt_c" name="M_2_Amino_4_hydroxy_6__erythro_1_2_3_trihydroxypropyl_dihydropteridine_triphosphate_C9H12N5O13P3" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
170 <species id="M_aicar_c" name="M_5_Amino_1__5_Phospho_D_ribosyl_imidazole_4_carboxamide_C9H13N4O8P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
171 <species id="M_air_c" name="M_5_amino_1__5_phospho_D_ribosyl_imidazole_C8H12N3O7P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
172 <species id="M_akg_c" name="M_2_Oxoglutarate_C5H4O5" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
173 <species id="M_akg_e" name="M_2_Oxoglutarate_C5H4O5" compartment="Extra_organism" charge="-2" boundaryCondition="false"/>
174 <species id="M_ala_B_c" name="M_beta_Alanine_C3H7NO2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
175 <species id="M_ala_D_c" name="M_D_Alanine_C3H7NO2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
176 <species id="M_ala_D_e" name="M_D_Alanine_C3H7NO2" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
177 <species id="M_ala_L_c" name="M_L_Alanine_C3H7NO2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
178 <species id="M_ala_L_e" name="M_L_Alanine_C3H7NO2" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
179 <species id="M_alaala_c" name="M_D_Alanyl_D_alanine_C6H12N2O3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
180 <species id="M_alac_S_c" name="M__S__2_Acetolactate_C5H7O4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
181 <species id="M_alltn_c" name="M_Allantoin_C4H6N4O3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
182 <species id="M_alltn_e" name="M_Allantoin_C4H6N4O3" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
183 <species id="M_alltt_c" name="M_Allantoate_C4H7N4O4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
184 <species id="M_altrn_c" name="M_D_Altronate_C6H11O7" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
185 <species id="M_amet_c" name="M_S_Adenosyl_L_methionine_C15H23N6O5S" compartment="Cytosol" charge="1" boundaryCondition="false"/>
186 <species id="M_ametam_c" name="M_S_Adenosylmethioninamine_C14H24N6O3S" compartment="Cytosol" charge="2" boundaryCondition="false"/>
187 <species id="M_amob_c" name="M_S_Adenosyl_4_methylthio_2_oxobutanoate_C15H19N5O6S" compartment="Cytosol" charge="0" boundaryCondition="false"/>
188 <species id="M_amp_c" name="M_AMP_C10H12N5O7P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
189 <species id="M_amp_e" name="M_AMP_C10H12N5O7P" compartment="Extra_organism" charge="-2" boundaryCondition="false"/>
190 <species id="M_anth_c" name="M_Anthranilate_C7H6NO2" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
191 <species id="M_ap4a_c" name="M_P1_P4_Bis_5__adenosyl__tetraphosphate_C20H24N10O19P4" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
192 <species id="M_ap5a_c" name="M_P1_P5_Bis_5__adenosyl__pentaphosphate_C20H24N10O22P5" compartment="Cytosol" charge="-5" boundaryCondition="false"/>
193 <species id="M_apg_EC_c" name="M_acyl_phosphatidylglycerol__Ecoli__C2829H5272O550P50" compartment="Cytosol" charge="-50" boundaryCondition="false"/>
194 <species id="M_apoACP_c" name="M_apoprotein_acyl_carrier_protein_RHO" compartment="Cytosol" charge="0" boundaryCondition="false"/>
195 <species id="M_aps_c" name="M_Adenosine_5__phosphosulfate_C10H12N5O10PS" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
196 <species id="M_ara5p_c" name="M_D_Arabinose_5_phosphate_C5H9O8P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
197 <species id="M_arab_L_c" name="M_L_Arabinose_C5H10O5" compartment="Cytosol" charge="0" boundaryCondition="false"/>
198 <species id="M_arab_L_e" name="M_L_Arabinose_C5H10O5" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
199 <species id="M_arbt6p_c" name="M_Arbutin_6_phosphate_C12H15O10P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
200 <species id="M_arg_L_c" name="M_L_Arginine_C6H15N4O2" compartment="Cytosol" charge="1" boundaryCondition="false"/>
201 <species id="M_arg_L_e" name="M_L_Arginine_C6H15N4O2" compartment="Extra_organism" charge="1" boundaryCondition="false"/>
202 <species id="M_argsuc_c" name="M_N_omega___L_Arginino_succinate_C10H17N4O6" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
203 <species id="M_asn_L_c" name="M_L_Asparagine_C4H8N2O3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
204 <species id="M_asn_L_e" name="M_L_Asparagine_C4H8N2O3" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
205 <species id="M_asp_L_c" name="M_L_Aspartate_C4H6NO4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
206 <species id="M_asp_L_e" name="M_L_Aspartate_C4H6NO4" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
207 <species id="M_aspsa_c" name="M_L_Aspartate_4_semialdehyde_C4H7NO3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
208 <species id="M_atp_c" name="M_ATP_C10H12N5O13P3" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
209 <species id="M_bbtcoa_c" name="M_gamma_butyrobetainyl_CoA_C28H46N8O17P3S" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
210 <species id="M_betald_c" name="M_Betaine_aldehyde_C5H12NO" compartment="Cytosol" charge="1" boundaryCondition="false"/>
211 <species id="M_btcoa_c" name="M_Butanoyl_CoA_C25H38N7O17P3S" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
212 <species id="M_btn_c" name="M_Biotin_C10H15N2O3S" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
213 <species id="M_btnso_c" name="M_d_biotin_d_sulfoxide_C10H15N2O4S" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
214 <species id="M_but_c" name="M_Butyrate__n_C40__C4H7O2" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
215 <species id="M_but_e" name="M_Butyrate__n_C40__C4H7O2" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
216 <species id="M_camp_c" name="M_cAMP_C10H11N5O6P" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
217 <species id="M_cbasp_c" name="M_N_Carbamoyl_L_aspartate_C5H6N2O5" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
218 <species id="M_cbi_c" name="M_Cobinamide_C48H72CoN11O8" compartment="Cytosol" charge="0" boundaryCondition="false"/>
219 <species id="M_cbl1_c" name="M_Cob_I_alamin_C62H88CoN13O14P" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
220 <species id="M_cbl1_e" name="M_Cob_I_alamin_C62H88CoN13O14P" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
221 <species id="M_cbp_c" name="M_Carbamoyl_phosphate_CH2NO5P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
222 <species id="M_cdp_c" name="M_CDP_C9H12N3O11P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
223 <species id="M_cdpdag_EC_c" name="M_CDPdiacylglycerol__E_coli__C2286H3998N150O750P100" compartment="Cytosol" charge="-100" boundaryCondition="false"/>
224 <species id="M_cdpea_c" name="M_CDPethanolamine_C11H19N4O11P2" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
225 <species id="M_cechddd_c" name="M_cis_3__3_carboxyethyl__3_5_cyclohexadiene_1_2_diol_C9H11O4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
226 <species id="M_cenchddd_c" name="M_cis_3__3_carboxyethenyl__3_5_cyclohexadiene_1_2_diol_C9H9O4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
227 <species id="M_chol_c" name="M_Choline_C5H14NO" compartment="Cytosol" charge="1" boundaryCondition="false"/>
228 <species id="M_chol_e" name="M_Choline_C5H14NO" compartment="Extra_organism" charge="1" boundaryCondition="false"/>
229 <species id="M_chor_c" name="M_chorismate_C10H8O6" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
230 <species id="M_cinnm_c" name="M_trans_Cinnamate_C9H7O2" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
231 <species id="M_cit_c" name="M_Citrate_C6H5O7" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
232 <species id="M_cit_e" name="M_Citrate_C6H5O7" compartment="Extra_organism" charge="-3" boundaryCondition="false"/>
233 <species id="M_citr_L_c" name="M_L_Citrulline_C6H13N3O3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
234 <species id="M_ckdo_c" name="M_CMP_3_deoxy_D_manno_octulosonate_C17H24N3O15P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
235 <species id="M_clpn_EC_c" name="M_Cardiolipin__Ecoli__C3822H7096O850P100" compartment="Cytosol" charge="-100" boundaryCondition="false"/>
236 <species id="M_cmp_c" name="M_CMP_C9H12N3O8P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
237 <species id="M_co2_c" name="M_CO2_CO2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
238 <species id="M_co2_e" name="M_CO2_CO2" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
239 <species id="M_coa_c" name="M_Coenzyme_A_C21H32N7O16P3S" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
240 <species id="M_cpppg3_c" name="M_Coproporphyrinogen_III_C36H40N4O8" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
241 <species id="M_crn_c" name="M_L_Carnitine_C7H15NO3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
242 <species id="M_crn_e" name="M_L_Carnitine_C7H15NO3" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
243 <species id="M_crncoa_c" name="M_L_Carnitinyl_CoA_C28H46N8O18P3S" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
244 <species id="M_csn_c" name="M_Cytosine_C4H5N3O" compartment="Cytosol" charge="0" boundaryCondition="false"/>
245 <species id="M_csn_e" name="M_Cytosine_C4H5N3O" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
246 <species id="M_ctbt_c" name="M_crotonobetaine_C7H13NO2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
247 <species id="M_ctbtcoa_c" name="M_crotonobetainyl_CoA_C28H44N8O17P3S" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
248 <species id="M_ctp_c" name="M_CTP_C9H12N3O14P3" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
249 <species id="M_cyan_c" name="M_Hydrogen_cyanide_CHN" compartment="Cytosol" charge="0" boundaryCondition="false"/>
250 <species id="M_cynt_c" name="M_Cyanate_CNO" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
251 <species id="M_cynt_e" name="M_Cyanate_CNO" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
252 <species id="M_cys_L_c" name="M_L_Cysteine_C3H7NO2S" compartment="Cytosol" charge="0" boundaryCondition="false"/>
253 <species id="M_cys_L_e" name="M_L_Cysteine_C3H7NO2S" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
254 <species id="M_cyst_L_c" name="M_L_Cystathionine_C7H14N2O4S" compartment="Cytosol" charge="0" boundaryCondition="false"/>
255 <species id="M_cytd_c" name="M_Cytidine_C9H13N3O5" compartment="Cytosol" charge="0" boundaryCondition="false"/>
256 <species id="M_cytd_e" name="M_Cytidine_C9H13N3O5" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
257 <species id="M_dad_2_c" name="M_Deoxyadenosine_C10H13N5O3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
258 <species id="M_dad_2_e" name="M_Deoxyadenosine_C10H13N5O3" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
259 <species id="M_dadp_c" name="M_dADP_C10H12N5O9P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
260 <species id="M_damp_c" name="M_dAMP_C10H12N5O6P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
261 <species id="M_dann_c" name="M_7_8_Diaminononanoate_C9H21N2O2" compartment="Cytosol" charge="1" boundaryCondition="false"/>
262 <species id="M_datp_c" name="M_dATP_C10H12N5O12P3" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
263 <species id="M_db4p_c" name="M_3_4_dihydroxy_2_butanone_4_phosphate_C4H7O6P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
264 <species id="M_dcamp_c" name="M_N6__1_2_Dicarboxyethyl__AMP_C14H14N5O11P" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
265 <species id="M_dcdp_c" name="M_dCDP_C9H12N3O10P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
266 <species id="M_dcmp_c" name="M_dCMP_C9H12N3O7P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
267 <species id="M_dctp_c" name="M_dCTP_C9H12N3O13P3" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
268 <species id="M_dcyt_c" name="M_Deoxycytidine_C9H13N3O4" compartment="Cytosol" charge="0" boundaryCondition="false"/>
269 <species id="M_dcyt_e" name="M_Deoxycytidine_C9H13N3O4" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
270 <species id="M_ddcaACP_c" name="M_Dodecanoyl_ACP__n_C120ACP__C23H43N2O8PRS" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
271 <species id="M_dgdp_c" name="M_dGDP_C10H12N5O10P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
272 <species id="M_dgmp_c" name="M_dGMP_C10H12N5O7P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
273 <species id="M_dgsn_c" name="M_Deoxyguanosine_C10H13N5O4" compartment="Cytosol" charge="0" boundaryCondition="false"/>
274 <species id="M_dgsn_e" name="M_Deoxyguanosine_C10H13N5O4" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
275 <species id="M_dgtp_c" name="M_dGTP_C10H12N5O13P3" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
276 <species id="M_dha_c" name="M_Dihydroxyacetone_C3H6O3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
277 <species id="M_dha_e" name="M_Dihydroxyacetone_C3H6O3" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
278 <species id="M_dhap_c" name="M_Dihydroxyacetone_phosphate_C3H5O6P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
279 <species id="M_dhcinnm_c" name="M_2_3_dihydroxicinnamic_acid_C9H7O4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
280 <species id="M_dhf_c" name="M_7_8_Dihydrofolate_C19H19N7O6" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
281 <species id="M_dhna_c" name="M_1_4_Dihydroxy_2_naphthoate_C11H7O4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
282 <species id="M_dhnpt_c" name="M_Dihydroneopterin_C9H13N5O4" compartment="Cytosol" charge="0" boundaryCondition="false"/>
283 <species id="M_dhor_S_c" name="M__S__Dihydroorotate_C5H5N2O4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
284 <species id="M_dhpmp_c" name="M_Dihydroneopterin_monophosphate_C9H12N5O7P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
285 <species id="M_dhpppn_c" name="M_3__2_3_Dihydroxyphenyl_propanoate_C9H9O4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
286 <species id="M_dhpt_c" name="M_Dihydropteroate_C14H13N6O3" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
287 <species id="M_dhptd_c" name="M_4_5_dihydroxy_2_3_pentanedione_C5H8O4" compartment="Cytosol" charge="0" boundaryCondition="false"/>
288 <species id="M_din_c" name="M_Deoxyinosine_C10H12N4O4" compartment="Cytosol" charge="0" boundaryCondition="false"/>
289 <species id="M_din_e" name="M_Deoxyinosine_C10H12N4O4" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
290 <species id="M_dkmpp_c" name="M_2_3_diketo_5_methylthio_1_phosphopentane_C6H9O6PS" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
291 <species id="M_dmbzid_c" name="M_5_6_Dimethylbenzimidazole_C9H10N2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
292 <species id="M_dmlz_c" name="M_6_7_Dimethyl_8__1_D_ribityl_lumazine_C13H18N4O6" compartment="Cytosol" charge="0" boundaryCondition="false"/>
293 <species id="M_dmpp_c" name="M_Dimethylallyl_diphosphate_C5H9O7P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
294 <species id="M_dms_c" name="M_Dimethyl_sulfide_C2H6S" compartment="Cytosol" charge="0" boundaryCondition="false"/>
295 <species id="M_dms_e" name="M_Dimethyl_sulfide_C2H6S" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
296 <species id="M_dmso_c" name="M_Dimethyl_sulfoxide_C2H6OS" compartment="Cytosol" charge="0" boundaryCondition="false"/>
297 <species id="M_dmso_e" name="M_Dimethyl_sulfoxide_C2H6OS" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
298 <species id="M_dnad_c" name="M_Deamino_NAD_C21H24N6O15P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
299 <species id="M_dpcoa_c" name="M_Dephospho_CoA_C21H33N7O13P2S" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
300 <species id="M_dscl_c" name="M_dihydrosirohydrochlorin_C42H41N4O16" compartment="Cytosol" charge="-7" boundaryCondition="false"/>
301 <species id="M_dtbt_c" name="M_Dethiobiotin_C10H17N2O3" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
302 <species id="M_dtdp4aaddg_c" name="M_dTDP_4_acetamido_4_6_dideoxy_D_galactose_C18H27N3O15P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
303 <species id="M_dtdp4addg_c" name="M_dTDP_4_amino_4_6_dideoxy_D_glucose_C16H26N3O14P2" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
304 <species id="M_dtdp4d6dg_c" name="M_dTDP_4_dehydro_6_deoxy_D_glucose_C16H22N2O15P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
305 <species id="M_dtdp4d6dm_c" name="M_dTDP_4_dehydro_6_deoxy_L_mannose_C16H22N2O15P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
306 <species id="M_dtdp_c" name="M_dTDP_C10H13N2O11P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
307 <species id="M_dtdpglu_c" name="M_dTDPglucose_C16H24N2O16P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
308 <species id="M_dtdprmn_c" name="M_dTDP_L_rhamnose_C16H24N2O15P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
309 <species id="M_dtmp_c" name="M_dTMP_C10H13N2O8P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
310 <species id="M_dttp_c" name="M_dTTP_C10H13N2O14P3" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
311 <species id="M_dudp_c" name="M_dUDP_C9H11N2O11P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
312 <species id="M_dump_c" name="M_dUMP_C9H11N2O8P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
313 <species id="M_duri_c" name="M_Deoxyuridine_C9H12N2O5" compartment="Cytosol" charge="0" boundaryCondition="false"/>
314 <species id="M_duri_e" name="M_Deoxyuridine_C9H12N2O5" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
315 <species id="M_dutp_c" name="M_dUTP_C9H11N2O14P3" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
316 <species id="M_dxyl5p_c" name="M_1_deoxy_D_xylulose_5_phosphate_C5H9O7P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
317 <species id="M_dxyl_c" name="M_1_deoxy_D_xylulose_C5H10O4" compartment="Cytosol" charge="0" boundaryCondition="false"/>
318 <species id="M_e4p_c" name="M_D_Erythrose_4_phosphate_C4H7O7P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
319 <species id="M_eca_EC_c" name="M_Enterobacterial_common_antigen_polysaccharide__Ecoli__C24H36N3O15" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
320 <species id="M_eig3p_c" name="M_D_erythro_1__Imidazol_4_yl_glycerol_3_phosphate_C6H9N2O6P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
321 <species id="M_enter_c" name="M_Enterochelin_C30H27N3O15" compartment="Cytosol" charge="0" boundaryCondition="false"/>
322 <species id="M_etha_c" name="M_Ethanolamine_C2H8NO" compartment="Cytosol" charge="1" boundaryCondition="false"/>
323 <species id="M_etoh_c" name="M_Ethanol_C2H6O" compartment="Cytosol" charge="0" boundaryCondition="false"/>
324 <species id="M_etoh_e" name="M_Ethanol_C2H6O" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
325 <species id="M_f1p_c" name="M_D_Fructose_1_phosphate_C6H11O9P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
326 <species id="M_f6p_c" name="M_D_Fructose_6_phosphate_C6H11O9P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
327 <species id="M_fad_c" name="M_Flavin_adenine_dinucleotide_oxidized_C27H31N9O15P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
328 <species id="M_fadh2_c" name="M_Flavin_adenine_dinucleotide_reduced_C27H33N9O15P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
329 <species id="M_fc1p_c" name="M_L_Fuculose_1_phosphate_C6H11O8P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
330 <species id="M_fcl_L_c" name="M_L_fuculose_C6H12O5" compartment="Cytosol" charge="0" boundaryCondition="false"/>
331 <species id="M_fdp_c" name="M_D_Fructose_1_6_bisphosphate_C6H10O12P2" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
332 <species id="M_fe2_c" name="M_Fe2_Fe" compartment="Cytosol" charge="2" boundaryCondition="false"/>
333 <species id="M_fe2_e" name="M_Fe2_Fe" compartment="Extra_organism" charge="2" boundaryCondition="false"/>
334 <species id="M_fgam_c" name="M_N2_Formyl_N1__5_phospho_D_ribosyl_glycinamide_C8H13N2O9P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
335 <species id="M_fmn_c" name="M_FMN_C17H19N4O9P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
336 <species id="M_for_c" name="M_Formate_CH1O2" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
337 <species id="M_for_e" name="M_Formate_CH1O2" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
338 <species id="M_fpram_c" name="M_2__Formamido__N1__5_phospho_D_ribosyl_acetamidine_C8H15N3O8P" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
339 <species id="M_fprica_c" name="M_5_Formamido_1__5_phospho_D_ribosyl_imidazole_4_carboxamide_C10H13N4O9P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
340 <species id="M_frdp_c" name="M_Farnesyl_diphosphate_C15H25O7P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
341 <species id="M_fru_c" name="M_D_Fructose_C6H12O6" compartment="Cytosol" charge="0" boundaryCondition="false"/>
342 <species id="M_fru_e" name="M_D_Fructose_C6H12O6" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
343 <species id="M_fruur_c" name="M_D_Fructuronate_C6H9O7" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
344 <species id="M_fuc1p_L_c" name="M_L_Fucose_1_phosphate_C6H11O8P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
345 <species id="M_fuc1p_L_e" name="M_L_Fucose_1_phosphate_C6H11O8P" compartment="Extra_organism" charge="-2" boundaryCondition="false"/>
346 <species id="M_fuc_L_c" name="M_L_Fucose_C6H12O5" compartment="Cytosol" charge="0" boundaryCondition="false"/>
347 <species id="M_fuc_L_e" name="M_L_Fucose_C6H12O5" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
348 <species id="M_fum_c" name="M_Fumarate_C4H2O4" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
349 <species id="M_fum_e" name="M_Fumarate_C4H2O4" compartment="Extra_organism" charge="-2" boundaryCondition="false"/>
350 <species id="M_g1p_c" name="M_D_Glucose_1_phosphate_C6H11O9P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
351 <species id="M_g3p_c" name="M_Glyceraldehyde_3_phosphate_C3H5O6P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
352 <species id="M_g3pc_c" name="M_sn_Glycero_3_phosphocholine_C8H20NO6P" compartment="Cytosol" charge="0" boundaryCondition="false"/>
353 <species id="M_g3pe_c" name="M_sn_Glycero_3_phosphoethanolamine_C5H14NO6P" compartment="Cytosol" charge="0" boundaryCondition="false"/>
354 <species id="M_g3pg_c" name="M_Glycerophosphoglycerol_C6H14O8P" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
355 <species id="M_g3pi_c" name="M_sn_Glycero_3_phospho_1_inositol_C9H18O11P" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
356 <species id="M_g3ps_c" name="M_Glycerophosphoserine_C6H13NO8P" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
357 <species id="M_g6p_c" name="M_D_Glucose_6_phosphate_C6H11O9P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
358 <species id="M_g6p_e" name="M_D_Glucose_6_phosphate_C6H11O9P" compartment="Extra_organism" charge="-2" boundaryCondition="false"/>
359 <species id="M_gal1p_c" name="M_alpha_D_Galactose_1_phosphate_C6H11O9P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
360 <species id="M_gal_c" name="M_D_Galactose_C6H12O6" compartment="Cytosol" charge="0" boundaryCondition="false"/>
361 <species id="M_gal_e" name="M_D_Galactose_C6H12O6" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
362 <species id="M_galct_D_c" name="M_D_Galactarate_C6H8O8" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
363 <species id="M_galct_D_e" name="M_D_Galactarate_C6H8O8" compartment="Extra_organism" charge="-2" boundaryCondition="false"/>
364 <species id="M_galctn_D_c" name="M_D_Galactonate_C6H11O7" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
365 <species id="M_galctn_D_e" name="M_D_Galactonate_C6H11O7" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
366 <species id="M_galt1p_c" name="M_Galactitol_1_phosphate_C6H13O9P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
367 <species id="M_galt_e" name="M_Galactitol_C6H14O6" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
368 <species id="M_galur_c" name="M_D_Galacturonate_C6H9O7" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
369 <species id="M_galur_e" name="M_D_Galacturonate_C6H9O7" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
370 <species id="M_gam1p_c" name="M_D_Glucosamine_1_phosphate_C6H13NO8P" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
371 <species id="M_gam6p_c" name="M_D_Glucosamine_6_phosphate_C6H13NO8P" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
372 <species id="M_gam_e" name="M_D_Glucosamine_C6H14NO5" compartment="Extra_organism" charge="1" boundaryCondition="false"/>
373 <species id="M_gar_c" name="M_N1__5_Phospho_D_ribosyl_glycinamide_C7H14N2O8P" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
374 <species id="M_gbbtn_c" name="M_gamma_butyrobetaine_C7H15NO2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
375 <species id="M_gbbtn_e" name="M_gamma_butyrobetaine_C7H15NO2" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
376 <species id="M_gcald_c" name="M_Glycolaldehyde_C2H4O2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
377 <species id="M_gdp_c" name="M_GDP_C10H12N5O11P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
378 <species id="M_gdpddman_c" name="M_GDP_4_dehydro_6_deoxy_D_mannose_C16H21N5O15P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
379 <species id="M_gdpfuc_c" name="M_GDP_L_fucose_C16H23N5O15P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
380 <species id="M_gdpmann_c" name="M_GDP_D_mannose_C16H23N5O16P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
381 <species id="M_gdpofuc_c" name="M_GDP_4_oxo_L_fucose_C16H21N5O15P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
382 <species id="M_glc_D_c" name="M_D_Glucose_C6H12O6" compartment="Cytosol" charge="0" boundaryCondition="false"/>
383 <species id="M_glc_D_e" name="M_D_Glucose_C6H12O6" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
384 <species id="M_glcn_c" name="M_D_Gluconate_C6H11O7" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
385 <species id="M_glcn_e" name="M_D_Gluconate_C6H11O7" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
386 <species id="M_glcr_c" name="M_D_Glucarate_C6H8O8" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
387 <species id="M_glcr_e" name="M_D_Glucarate_C6H8O8" compartment="Extra_organism" charge="-2" boundaryCondition="false"/>
388 <species id="M_glcur_c" name="M_D_Glucuronate_C6H9O7" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
389 <species id="M_glcur_e" name="M_D_Glucuronate_C6H9O7" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
390 <species id="M_gln_L_c" name="M_L_Glutamine_C5H10N2O3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
391 <species id="M_gln_L_e" name="M_L_Glutamine_C5H10N2O3" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
392 <species id="M_glu1sa_c" name="M_L_Glutamate_1_semialdehyde_C5H9NO3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
393 <species id="M_glu5p_c" name="M_L_Glutamate_5_phosphate_C5H8NO7P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
394 <species id="M_glu5sa_c" name="M_L_Glutamate_5_semialdehyde_C5H9NO3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
395 <species id="M_glu_D_c" name="M_D_Glutamate_C5H8NO4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
396 <species id="M_glu_L_c" name="M_L_Glutamate_C5H8NO4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
397 <species id="M_glu_L_e" name="M_L_Glutamate_C5H8NO4" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
398 <species id="M_glucys_c" name="M_gamma_L_Glutamyl_L_cysteine_C8H13N2O5S" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
399 <species id="M_glutrna_c" name="M_L_Glutamyl_tRNA_Glu__C5H7NO3R" compartment="Cytosol" charge="0" boundaryCondition="false"/>
400 <species id="M_glx_c" name="M_Glyoxylate_C2H1O3" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
401 <species id="M_gly_c" name="M_Glycine_C2H5NO2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
402 <species id="M_gly_e" name="M_Glycine_C2H5NO2" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
403 <species id="M_glyald_c" name="M_D_Glyceraldehyde_C3H6O3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
404 <species id="M_glyald_e" name="M_D_Glyceraldehyde_C3H6O3" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
405 <species id="M_glyb_c" name="M_Glycine_betaine_C5H11NO2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
406 <species id="M_glyb_e" name="M_Glycine_betaine_C5H11NO2" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
407 <species id="M_glyc3p_c" name="M_Glycerol_3_phosphate_C3H7O6P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
408 <species id="M_glyc3p_e" name="M_Glycerol_3_phosphate_C3H7O6P" compartment="Extra_organism" charge="-2" boundaryCondition="false"/>
409 <species id="M_glyc_R_c" name="M__R__Glycerate_C3H5O4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
410 <species id="M_glyc_c" name="M_Glycerol_C3H8O3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
411 <species id="M_glyc_e" name="M_Glycerol_C3H8O3" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
412 <species id="M_glyclt_c" name="M_Glycolate_C2H3O3" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
413 <species id="M_glyclt_e" name="M_Glycolate_C2H3O3" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
414 <species id="M_glycogen_c" name="M_glycogen_C6H10O5" compartment="Cytosol" charge="0" boundaryCondition="false"/>
415 <species id="M_gmhep17bp_c" name="M_D_Glycero_D_manno_heptose_1_7_bisphosphate_C7H12O13P2" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
416 <species id="M_gmhep1p_c" name="M_D_Glycero_D_manno_heptose_1_phosphate_C7H13O10P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
417 <species id="M_gmhep7p_c" name="M_D_Glycero_D_manno_heptose_7_phosphate_C7H13O10P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
418 <species id="M_gmp_c" name="M_GMP_C10H12N5O8P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
419 <species id="M_gp4g_c" name="M_P1_P4_Bis_5__guanosyl__tetraphosphate_C20H24N10O21P4" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
420 <species id="M_grdp_c" name="M_Geranyl_diphosphate_C10H17O7P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
421 <species id="M_gsn_c" name="M_Guanosine_C10H13N5O5" compartment="Cytosol" charge="0" boundaryCondition="false"/>
422 <species id="M_gsn_e" name="M_Guanosine_C10H13N5O5" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
423 <species id="M_gthox_c" name="M_Oxidized_glutathione_C20H30N6O12S2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
424 <species id="M_gthrd_c" name="M_Reduced_glutathione_C10H16N3O6S" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
425 <species id="M_gtp_c" name="M_GTP_C10H12N5O14P3" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
426 <species id="M_gtspmd_c" name="M_Glutathionylspermidine_C17H36N6O5S" compartment="Cytosol" charge="2" boundaryCondition="false"/>
427 <species id="M_gua_c" name="M_Guanine_C5H5N5O" compartment="Cytosol" charge="0" boundaryCondition="false"/>
428 <species id="M_gua_e" name="M_Guanine_C5H5N5O" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
429 <species id="M_h2_c" name="M_H2_H2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
430 <species id="M_h2mb4p_c" name="M_1_hydroxy_2_methyl_2__E__butenyl_4_diphosphate_C5H9O8P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
431 <species id="M_h2o2_c" name="M_Hydrogen_peroxide_H2O2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
432 <species id="M_h2o_c" name="M_H2O_H2O" compartment="Cytosol" charge="0" boundaryCondition="false"/>
433 <species id="M_h2o_e" name="M_H2O_H2O" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
434 <species id="M_h2s_c" name="M_Hydrogen_sulfide_H2S" compartment="Cytosol" charge="0" boundaryCondition="false"/>
435 <species id="M_h_c" name="M_H_H" compartment="Cytosol" charge="1" boundaryCondition="false"/>
436 <species id="M_h_e" name="M_H_H" compartment="Extra_organism" charge="1" boundaryCondition="false"/>
437 <species id="M_hco3_c" name="M_Bicarbonate_CHO3" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
438 <species id="M_hcys_L_c" name="M_L_Homocysteine_C4H9NO2S" compartment="Cytosol" charge="0" boundaryCondition="false"/>
439 <species id="M_hdca_c" name="M_Hexadecanoate__n_C160__C16H31O2" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
440 <species id="M_hdca_e" name="M_Hexadecanoate__n_C160__C16H31O2" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
441 <species id="M_hdcea_c" name="M_Hexadecenoate__n_C161__C16H29O2" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
442 <species id="M_hdeACP_c" name="M_cis_hexadec_9_enoyl_acyl_carrier_protein__n_C161__C27H49N2O8PRS" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
443 <species id="M_hemeO_c" name="M_Heme_O_C49H56FeN4O5" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
444 <species id="M_his_L_c" name="M_L_Histidine_C6H9N3O2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
445 <species id="M_his_L_e" name="M_L_Histidine_C6H9N3O2" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
446 <species id="M_hisp_c" name="M_L_Histidinol_phosphate_C6H11N3O4P" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
447 <species id="M_histd_c" name="M_L_Histidinol_C6H12N3O" compartment="Cytosol" charge="1" boundaryCondition="false"/>
448 <species id="M_hkndd_c" name="M_2_Hydroxy_6_oxonona_2_4_diene_1_9_dioate_C9H8O6" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
449 <species id="M_hkntd_c" name="M_2_hydroxy_6_ketononatrienedioate_C9H6O6" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
450 <species id="M_hmbil_c" name="M_Hydroxymethylbilane_C40H38N4O17" compartment="Cytosol" charge="-8" boundaryCondition="false"/>
451 <species id="M_hmfurn_c" name="M_4_hydroxy_5_methyl_3_2H__furanone_C5H6O3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
452 <species id="M_hom_L_c" name="M_L_Homoserine_C4H9NO3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
453 <species id="M_hpyr_c" name="M_Hydroxypyruvate_C3H3O4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
454 <species id="M_hqn_c" name="M_Hydroquinone_C6H6O2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
455 <species id="M_hxan_c" name="M_Hypoxanthine_C5H4N4O" compartment="Cytosol" charge="0" boundaryCondition="false"/>
456 <species id="M_hxan_e" name="M_Hypoxanthine_C5H4N4O" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
457 <species id="M_iasp_c" name="M_Iminoaspartate_C4H3NO4" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
458 <species id="M_ichor_c" name="M_Isochorismate_C10H8O6" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
459 <species id="M_icit_c" name="M_Isocitrate_C6H5O7" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
460 <species id="M_idon_L_c" name="M_L_Idonate_C6H11O7" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
461 <species id="M_idon_L_e" name="M_L_Idonate_C6H11O7" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
462 <species id="M_idp_c" name="M_IDP_C10H11N4O11P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
463 <species id="M_ile_L_c" name="M_L_Isoleucine_C6H13NO2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
464 <species id="M_ile_L_e" name="M_L_Isoleucine_C6H13NO2" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
465 <species id="M_imacp_c" name="M_3__Imidazol_4_yl__2_oxopropyl_phosphate_C6H7N2O5P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
466 <species id="M_imp_c" name="M_IMP_C10H11N4O8P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
467 <species id="M_indole_c" name="M_Indole_C8H7N" compartment="Cytosol" charge="0" boundaryCondition="false"/>
468 <species id="M_indole_e" name="M_Indole_C8H7N" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
469 <species id="M_inost_c" name="M_myo_Inositol_C6H12O6" compartment="Cytosol" charge="0" boundaryCondition="false"/>
470 <species id="M_ins_c" name="M_Inosine_C10H12N4O5" compartment="Cytosol" charge="0" boundaryCondition="false"/>
471 <species id="M_ins_e" name="M_Inosine_C10H12N4O5" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
472 <species id="M_ipdp_c" name="M_Isopentenyl_diphosphate_C5H9O7P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
473 <species id="M_itp_c" name="M_ITP_C10H11N4O14P3" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
474 <species id="M_k_c" name="M_potassium_K" compartment="Cytosol" charge="1" boundaryCondition="false"/>
475 <species id="M_k_e" name="M_potassium_K" compartment="Extra_organism" charge="1" boundaryCondition="false"/>
476 <species id="M_kdo2lipid4L_c" name="M_KDO_2__lipid_IV_A__with_laurate_C96H170N2O38P2" compartment="Cytosol" charge="-6" boundaryCondition="false"/>
477 <species id="M_kdo2lipid4_c" name="M_KDO_2__lipid_IV_A__C84H148N2O37P2" compartment="Cytosol" charge="-6" boundaryCondition="false"/>
478 <species id="M_kdo2lipid4p_c" name="M_KDO_2__lipid_IV_A__with_palmitoleoyl_C100H176N2O38P2" compartment="Cytosol" charge="-6" boundaryCondition="false"/>
479 <species id="M_kdo8p_c" name="M_3_Deoxy_D_manno_octulosonate_8_phosphate_C8H12O11P" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
480 <species id="M_kdo_c" name="M_3_Deoxy_D_manno_2_octulosonate_C8H13O8" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
481 <species id="M_kdolipid4_c" name="M_KDO_lipid_IV_A__C76H137N2O30P2" compartment="Cytosol" charge="-5" boundaryCondition="false"/>
482 <species id="M_lac_D_c" name="M_D_Lactate_C3H5O3" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
483 <species id="M_lac_D_e" name="M_D_Lactate_C3H5O3" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
484 <species id="M_lac_L_c" name="M_L_Lactate_C3H5O3" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
485 <species id="M_lac_L_e" name="M_L_Lactate_C3H5O3" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
486 <species id="M_lald_L_c" name="M_L_Lactaldehyde_C3H6O2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
487 <species id="M_lcts_c" name="M_Lactose_C12H22O11" compartment="Cytosol" charge="0" boundaryCondition="false"/>
488 <species id="M_lcts_e" name="M_Lactose_C12H22O11" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
489 <species id="M_leu_L_c" name="M_L_Leucine_C6H13NO2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
490 <species id="M_leu_L_e" name="M_L_Leucine_C6H13NO2" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
491 <species id="M_lgt_S_c" name="M__R__S_Lactoylglutathione_C13H20N3O8S" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
492 <species id="M_lipa_c" name="M_KDO_2__lipid__A__C110H196N2O39P2" compartment="Cytosol" charge="-6" boundaryCondition="false"/>
493 <species id="M_lipa_cold_c" name="M_cold_adapted_KDO_2__lipid__A__C114H202N2O39P2" compartment="Cytosol" charge="-6" boundaryCondition="false"/>
494 <species id="M_lipidA_c" name="M_2_3_2_3__Tetrakis_beta_hydroxymyristoyl__D_glucosaminyl_1_6_beta_D_glucosamine_1_4__bisphosphate_C68H126N2O23P2" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
495 <species id="M_lipidAds_c" name="M_Lipid_A_Disaccharide_C68H127N2O20P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
496 <species id="M_lipidX_c" name="M_2_3_Bis_3_hydroxytetradecanoyl__beta_D_glucosaminyl_1_phosphate_C34H64NO12P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
497 <species id="M_lps_EC_c" name="M_lipopolysaccharide__Ecoli__C171H297N4O88P2" compartment="Cytosol" charge="-7" boundaryCondition="false"/>
498 <species id="M_lys_L_c" name="M_L_Lysine_C6H15N2O2" compartment="Cytosol" charge="1" boundaryCondition="false"/>
499 <species id="M_lys_L_e" name="M_L_Lysine_C6H15N2O2" compartment="Extra_organism" charge="1" boundaryCondition="false"/>
500 <species id="M_malACP_c" name="M_Malonyl_acyl_carrier_protein_C14H22N2O10PRS" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
501 <species id="M_mal_L_c" name="M_L_Malate_C4H4O5" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
502 <species id="M_mal_L_e" name="M_L_Malate_C4H4O5" compartment="Extra_organism" charge="-2" boundaryCondition="false"/>
503 <species id="M_malcoa_c" name="M_Malonyl_CoA_C24H33N7O19P3S" compartment="Cytosol" charge="-5" boundaryCondition="false"/>
504 <species id="M_malt6p_c" name="M_Maltose_6__phosphate_C12H21O14P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
505 <species id="M_malt_c" name="M_Maltose_C12H22O11" compartment="Cytosol" charge="0" boundaryCondition="false"/>
506 <species id="M_malt_e" name="M_Maltose_C12H22O11" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
507 <species id="M_malthp_c" name="M_Maltoheptaose_C42H72O36" compartment="Cytosol" charge="0" boundaryCondition="false"/>
508 <species id="M_malthx_c" name="M_Maltohexaose_C36H62O31" compartment="Cytosol" charge="0" boundaryCondition="false"/>
509 <species id="M_malthx_e" name="M_Maltohexaose_C36H62O31" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
510 <species id="M_maltpt_c" name="M_Maltopentaose_C30H52O26" compartment="Cytosol" charge="0" boundaryCondition="false"/>
511 <species id="M_maltpt_e" name="M_Maltopentaose_C30H52O26" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
512 <species id="M_malttr_c" name="M_Maltotriose_C18H32O16" compartment="Cytosol" charge="0" boundaryCondition="false"/>
513 <species id="M_malttr_e" name="M_Maltotriose_C18H32O16" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
514 <species id="M_maltttr_c" name="M_Maltotetraose_C24H42O21" compartment="Cytosol" charge="0" boundaryCondition="false"/>
515 <species id="M_maltttr_e" name="M_Maltotetraose_C24H42O21" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
516 <species id="M_man1p_c" name="M_D_Mannose_1_phosphate_C6H11O9P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
517 <species id="M_man6p_c" name="M_D_Mannose_6_phosphate_C6H11O9P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
518 <species id="M_man6p_e" name="M_D_Mannose_6_phosphate_C6H11O9P" compartment="Extra_organism" charge="-2" boundaryCondition="false"/>
519 <species id="M_man_e" name="M_D_Mannose_C6H12O6" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
520 <species id="M_mana_c" name="M_D_Mannonate_C6H11O7" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
521 <species id="M_melib_c" name="M_Melibiose_C12H22O11" compartment="Cytosol" charge="0" boundaryCondition="false"/>
522 <species id="M_melib_e" name="M_Melibiose_C12H22O11" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
523 <species id="M_met_D_c" name="M_D_Methionine_C5H10NO2S" compartment="Cytosol" charge="0" boundaryCondition="false"/>
524 <species id="M_met_D_e" name="M_D_Methionine_C5H10NO2S" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
525 <species id="M_met_L_c" name="M_L_Methionine_C5H11NO2S" compartment="Cytosol" charge="0" boundaryCondition="false"/>
526 <species id="M_met_L_e" name="M_L_Methionine_C5H11NO2S" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
527 <species id="M_methf_c" name="M_5_10_Methenyltetrahydrofolate_C20H20N7O6" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
528 <species id="M_mi1p_D_c" name="M_1D_myo_Inositol_1_phosphate_C6H11O9P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
529 <species id="M_micit_c" name="M_methylisocitrate_C7H7O7" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
530 <species id="M_mlthf_c" name="M_5_10_Methylenetetrahydrofolate_C20H21N7O6" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
531 <species id="M_mmcoa_R_c" name="M__R__Methylmalonyl_CoA_C25H35N7O19P3S" compartment="Cytosol" charge="-5" boundaryCondition="false"/>
532 <species id="M_mmcoa_S_c" name="M__S__Methylmalonyl_CoA_C25H35N7O19P3S" compartment="Cytosol" charge="-5" boundaryCondition="false"/>
533 <species id="M_mnl1p_c" name="M_D_Mannitol_1_phosphate_C6H13O9P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
534 <species id="M_mnl_e" name="M_D_Mannitol_C6H14O6" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
535 <species id="M_mql8_c" name="M_Menaquinol_8_C51H74O2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
536 <species id="M_mqn8_c" name="M_Menaquinone_8_C51H72O2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
537 <species id="M_mthgxl_c" name="M_Methylglyoxal_C3H4O2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
538 <species id="M_myrsACP_c" name="M_Myristoyl_ACP__n_C140ACP__C25H47N2O8PRS" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
539 <species id="M_n8aspmd_c" name="M_N8_Acetylspermidine_C9H23N3O" compartment="Cytosol" charge="2" boundaryCondition="false"/>
540 <species id="M_na1_c" name="M_Sodium_Na" compartment="Cytosol" charge="1" boundaryCondition="false"/>
541 <species id="M_na1_e" name="M_Sodium_Na" compartment="Extra_organism" charge="1" boundaryCondition="false"/>
542 <species id="M_nac_c" name="M_Nicotinate_C6H4NO2" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
543 <species id="M_nac_e" name="M_Nicotinate_C6H4NO2" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
544 <species id="M_nad_c" name="M_Nicotinamide_adenine_dinucleotide_C21H26N7O14P2" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
545 <species id="M_nad_e" name="M_Nicotinamide_adenine_dinucleotide_C21H26N7O14P2" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
546 <species id="M_nadh_c" name="M_Nicotinamide_adenine_dinucleotide___reduced_C21H27N7O14P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
547 <species id="M_nadp_c" name="M_Nicotinamide_adenine_dinucleotide_phosphate_C21H25N7O17P3" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
548 <species id="M_nadph_c" name="M_Nicotinamide_adenine_dinucleotide_phosphate___reduced_C21H26N7O17P3" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
549 <species id="M_ncam_c" name="M_Nicotinamide_C6H6N2O" compartment="Cytosol" charge="0" boundaryCondition="false"/>
550 <species id="M_nh4_c" name="M_Ammonium_H4N" compartment="Cytosol" charge="1" boundaryCondition="false"/>
551 <species id="M_nh4_e" name="M_Ammonium_H4N" compartment="Extra_organism" charge="1" boundaryCondition="false"/>
552 <species id="M_nicrnt_c" name="M_Nicotinate_D_ribonucleotide_C11H12NO9P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
553 <species id="M_nmn_c" name="M_NMN_C11H14N2O8P" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
554 <species id="M_nmn_e" name="M_NMN_C11H14N2O8P" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
555 <species id="M_no2_c" name="M_Nitrite_NO2" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
556 <species id="M_no2_e" name="M_Nitrite_NO2" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
557 <species id="M_no3_c" name="M_Nitrate_NO3" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
558 <species id="M_no3_e" name="M_Nitrate_NO3" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
559 <species id="M_o2_c" name="M_O2_O2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
560 <species id="M_o2_e" name="M_O2_O2" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
561 <species id="M_o2s_c" name="M_Superoxide_anion_O2" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
562 <species id="M_oaa_c" name="M_Oxaloacetate_C4H2O5" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
563 <species id="M_ocdca_c" name="M_octadecanoate__n_C180__C18H35O2" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
564 <species id="M_ocdca_e" name="M_octadecanoate__n_C180__C18H35O2" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
565 <species id="M_ocdcea_c" name="M_octadecenoate__n_C181__C18H33O2" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
566 <species id="M_octdp_c" name="M_all_trans_Octaprenyl_diphosphate_C40H65O7P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
567 <species id="M_octeACP_c" name="M_cis_octadec_11_enoyl_acyl_carrier_protein__n_C181__C29H53N2O8PRS" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
568 <species id="M_ohpb_c" name="M_2_Oxo_3_hydroxy_4_phosphobutanoate_C4H4O8P" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
569 <species id="M_op4en_c" name="M_2_Oxopent_4_enoate_C5H5O3" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
570 <species id="M_orn_c" name="M_Ornithine_C5H13N2O2" compartment="Cytosol" charge="1" boundaryCondition="false"/>
571 <species id="M_orn_e" name="M_Ornithine_C5H13N2O2" compartment="Extra_organism" charge="1" boundaryCondition="false"/>
572 <species id="M_orot5p_c" name="M_Orotidine_5__phosphate_C10H10N2O11P" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
573 <species id="M_orot_c" name="M_Orotate_C5H3N2O4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
574 <species id="M_pa_EC_c" name="M_phosphatidate___Ecoli__C1836H3398O400P50" compartment="Cytosol" charge="-100" boundaryCondition="false"/>
575 <species id="M_pac_c" name="M_Phenylacetic_acid_C8H7O2" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
576 <species id="M_pacald_c" name="M_Phenylacetaldehyde_C8H8O" compartment="Cytosol" charge="0" boundaryCondition="false"/>
577 <species id="M_palmACP_c" name="M_Palmitoyl_ACP__n_C160ACP__C27H51N2O8PRS" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
578 <species id="M_pan4p_c" name="M_Pantetheine_4__phosphate_C11H21N2O7PS" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
579 <species id="M_pant_R_c" name="M__R__Pantoate_C6H11O4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
580 <species id="M_pap_c" name="M_Adenosine_3__5__bisphosphate_C10H11N5O10P2" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
581 <species id="M_paps_c" name="M_3__Phosphoadenylyl_sulfate_C10H11N5O13P2S" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
582 <species id="M_pc_EC_c" name="M_Phosphatidylcholine__Ecoli__C2086H4048N50O400P50" compartment="Cytosol" charge="0" boundaryCondition="false"/>
583 <species id="M_pdx5p_c" name="M_Pyridoxine_5__phosphate_C8H10NO6P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
584 <species id="M_pe_EC_c" name="M_Phosphatidylethanolamine__ecoli__C1936H3748N50O400P50" compartment="Cytosol" charge="0" boundaryCondition="false"/>
585 <species id="M_peamn_c" name="M_Phenethylamine_C8H12N" compartment="Cytosol" charge="1" boundaryCondition="false"/>
586 <species id="M_pep_c" name="M_Phosphoenolpyruvate_C3H2O6P" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
587 <species id="M_peptido_EC_c" name="M_Peptidoglycan_subunit_of_Escherichia_coli_C40H62N8O21" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
588 <species id="M_pg_EC_c" name="M_Phosphatidylglycerol__Ecoli__C1986H3748O500P50" compartment="Cytosol" charge="-50" boundaryCondition="false"/>
589 <species id="M_pgp_EC_c" name="M_Phosphatidylglycerophosphate__Ecoli__C1986H3698O650P100" compartment="Cytosol" charge="-150" boundaryCondition="false"/>
590 <species id="M_phaccoa_c" name="M_Phenylacetyl_CoA_C29H38N7O17P3S" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
591 <species id="M_phe_L_c" name="M_L_Phenylalanine_C9H11NO2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
592 <species id="M_phe_L_e" name="M_L_Phenylalanine_C9H11NO2" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
593 <species id="M_pheme_c" name="M_Protoheme_C34H30FeN4O4" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
594 <species id="M_phom_c" name="M_O_Phospho_L_homoserine_C4H8NO6P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
595 <species id="M_phpyr_c" name="M_Phenylpyruvate_C9H7O3" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
596 <species id="M_phthr_c" name="M_O_Phospho_4_hydroxy_L_threonine_C4H8NO7P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
597 <species id="M_pi_c" name="M_Phosphate_HO4P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
598 <species id="M_pi_e" name="M_Phosphate_HO4P" compartment="Extra_organism" charge="-2" boundaryCondition="false"/>
599 <species id="M_pmcoa_c" name="M_Pimeloyl_CoA_C28H41N7O19P3S" compartment="Cytosol" charge="-5" boundaryCondition="false"/>
600 <species id="M_pnto_R_c" name="M__R__Pantothenate_C9H16NO5" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
601 <species id="M_pnto_R_e" name="M__R__Pantothenate_C9H16NO5" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
602 <species id="M_ppa_c" name="M_Propionate__n_C30__C3H5O2" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
603 <species id="M_ppap_c" name="M_Propanoyl_phosphate_C3H5O5P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
604 <species id="M_ppbng_c" name="M_Porphobilinogen_C10H13N2O4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
605 <species id="M_ppcoa_c" name="M_Propanoyl_CoA_C24H36N7O17P3S" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
606 <species id="M_pphn_c" name="M_Prephenate_C10H8O6" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
607 <species id="M_ppi_c" name="M_Diphosphate_HO7P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
608 <species id="M_ppp9_c" name="M_Protoporphyrin_C34H32N4O4" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
609 <species id="M_pppg9_c" name="M_Protoporphyrinogen_IX_C34H38N4O4" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
610 <species id="M_pppi_c" name="M_Inorganic_triphosphate_HO10P3" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
611 <species id="M_pppn_c" name="M_Phenylpropanoate_C9H9O2" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
612 <species id="M_pppn_e" name="M_Phenylpropanoate_C9H9O2" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
613 <species id="M_pram_c" name="M_5_Phospho_beta_D_ribosylamine_C5H11NO7P" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
614 <species id="M_pran_c" name="M_N__5_Phospho_D_ribosyl_anthranilate_C12H13NO9P" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
615 <species id="M_prbamp_c" name="M_1__5_Phosphoribosyl__AMP_C15H19N5O14P2" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
616 <species id="M_prbatp_c" name="M_1__5_Phosphoribosyl__ATP_C15H19N5O20P4" compartment="Cytosol" charge="-6" boundaryCondition="false"/>
617 <species id="M_prfp_c" name="M_1__5_Phosphoribosyl__5__5_phosphoribosylamino_methylideneaminoimidazole_4_carboxamide_C15H21N5O15P2" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
618 <species id="M_prlp_c" name="M_5__5_phospho_1_deoxyribulos_1_ylamino_methylideneamino_1__5_phosphoribosyl_imidazole_4_carboxamide_C15H21N5O15P2" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
619 <species id="M_pro_L_c" name="M_L_Proline_C5H9NO2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
620 <species id="M_pro_L_e" name="M_L_Proline_C5H9NO2" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
621 <species id="M_prpp_c" name="M_5_Phospho_alpha_D_ribose_1_diphosphate_C5H8O14P3" compartment="Cytosol" charge="-5" boundaryCondition="false"/>
622 <species id="M_ps_EC_c" name="M_phosphatidylserine__Ecoli__C1986H3698N50O500P50" compartment="Cytosol" charge="-50" boundaryCondition="false"/>
623 <species id="M_pser_L_c" name="M_O_Phospho_L_serine_C3H6NO6P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
624 <species id="M_ptrc_c" name="M_Putrescine_C4H14N2" compartment="Cytosol" charge="2" boundaryCondition="false"/>
625 <species id="M_ptrc_e" name="M_Putrescine_C4H14N2" compartment="Extra_organism" charge="2" boundaryCondition="false"/>
626 <species id="M_pyam5p_c" name="M_Pyridoxamine_5__phosphate_C8H12N2O5P" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
627 <species id="M_pydam_c" name="M_Pyridoxamine_C8H13N2O2" compartment="Cytosol" charge="1" boundaryCondition="false"/>
628 <species id="M_pydx5p_c" name="M_Pyridoxal_5__phosphate_C8H8NO6P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
629 <species id="M_pydx_c" name="M_Pyridoxal_C8H9NO3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
630 <species id="M_pydxn_c" name="M_Pyridoxine_C8H11NO3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
631 <species id="M_pyr_c" name="M_Pyruvate_C3H3O3" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
632 <species id="M_pyr_e" name="M_Pyruvate_C3H3O3" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
633 <species id="M_q8_c" name="M_Ubiquinone_8_C49H74O4" compartment="Cytosol" charge="0" boundaryCondition="false"/>
634 <species id="M_q8h2_c" name="M_Ubiquinol_8_C49H76O4" compartment="Cytosol" charge="0" boundaryCondition="false"/>
635 <species id="M_quln_c" name="M_Quinolinate_C7H3NO4" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
636 <species id="M_r1p_c" name="M_alpha_D_Ribose_1_phosphate_C5H9O8P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
637 <species id="M_r5p_c" name="M_alpha_D_Ribose_5_phosphate_C5H9O8P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
638 <species id="M_rbl_L_c" name="M_L_Ribulose_C5H10O5" compartment="Cytosol" charge="0" boundaryCondition="false"/>
639 <species id="M_rdmbzi_c" name="M_N1__alpha_D_ribosyl__5_6_dimethylbenzimidazole_C14H18N2O4" compartment="Cytosol" charge="0" boundaryCondition="false"/>
640 <species id="M_rhcys_c" name="M_S_Ribosyl_L_homocysteine_C9H17NO6S" compartment="Cytosol" charge="0" boundaryCondition="false"/>
641 <species id="M_rib_D_c" name="M_D_Ribose_C5H10O5" compartment="Cytosol" charge="0" boundaryCondition="false"/>
642 <species id="M_rib_D_e" name="M_D_Ribose_C5H10O5" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
643 <species id="M_ribflv_c" name="M_Riboflavin_C17H20N4O6" compartment="Cytosol" charge="0" boundaryCondition="false"/>
644 <species id="M_rml1p_c" name="M_L_Rhamnulose_1_phosphate_C6H11O8P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
645 <species id="M_rml_c" name="M_L_Rhamnulose_C6H12O5" compartment="Cytosol" charge="0" boundaryCondition="false"/>
646 <species id="M_rmn_c" name="M_L_Rhamnose_C6H12O5" compartment="Cytosol" charge="0" boundaryCondition="false"/>
647 <species id="M_rmn_e" name="M_L_Rhamnose_C6H12O5" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
648 <species id="M_ru5p_D_c" name="M_D_Ribulose_5_phosphate_C5H9O8P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
649 <species id="M_ru5p_L_c" name="M_L_Ribulose_5_phosphate_C5H9O8P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
650 <species id="M_s7p_c" name="M_Sedoheptulose_7_phosphate_C7H13O10P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
651 <species id="M_sbt6p_c" name="M_D_Sorbitol_6_phosphate_C6H13O9P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
652 <species id="M_sbt_D_e" name="M_D_Sorbitol_C6H14O6" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
653 <species id="M_sbzcoa_c" name="M_O_Succinylbenzoyl_CoA_C32H39N7O20P3S" compartment="Cytosol" charge="-5" boundaryCondition="false"/>
654 <species id="M_scl_c" name="M_sirohydrochlorin_C42H39N4O16" compartment="Cytosol" charge="-7" boundaryCondition="false"/>
655 <species id="M_seln_c" name="M_Selenide_HSe" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
656 <species id="M_selnp_c" name="M_Selenophosphate_H2O3PSe" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
657 <species id="M_ser_D_c" name="M_D_Serine_C3H7NO3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
658 <species id="M_ser_D_e" name="M_D_Serine_C3H7NO3" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
659 <species id="M_ser_L_c" name="M_L_Serine_C3H7NO3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
660 <species id="M_ser_L_e" name="M_L_Serine_C3H7NO3" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
661 <species id="M_seramp_c" name="M_L_seryl_AMP_C13H19N6O9P" compartment="Cytosol" charge="0" boundaryCondition="false"/>
662 <species id="M_sheme_c" name="M_Siroheme_C42H36FeN4O16" compartment="Cytosol" charge="-8" boundaryCondition="false"/>
663 <species id="M_skm5p_c" name="M_Shikimate_5_phosphate_C7H8O8P" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
664 <species id="M_skm_c" name="M_Shikimate_C7H9O5" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
665 <species id="M_sl26da_c" name="M_N_Succinyl_LL_2_6_diaminoheptanedioate_C11H16N2O7" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
666 <species id="M_sl2a6o_c" name="M_N_Succinyl_2_L_amino_6_oxoheptanedioate_C11H12NO8" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
667 <species id="M_so3_c" name="M_Sulfite_O3S" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
668 <species id="M_so4_c" name="M_Sulfate_O4S" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
669 <species id="M_so4_e" name="M_Sulfate_O4S" compartment="Extra_organism" charge="-2" boundaryCondition="false"/>
670 <species id="M_spmd_c" name="M_Spermidine_C7H22N3" compartment="Cytosol" charge="3" boundaryCondition="false"/>
671 <species id="M_spmd_e" name="M_Spermidine_C7H22N3" compartment="Extra_organism" charge="3" boundaryCondition="false"/>
672 <species id="M_ssaltpp_c" name="M_Succinate_semialdehyde_thiamin_diphosphate_anion_C16H21N4O10P2S" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
673 <species id="M_suc6p_c" name="M_Sucrose_6_phosphate_C12H21O14P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
674 <species id="M_sucarg_c" name="M_N2_Succinyl_L_arginine_C10H17N4O5" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
675 <species id="M_sucbz_c" name="M_o_Succinylbenzoate_C11H8O5" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
676 <species id="M_succ_c" name="M_Succinate_C4H4O4" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
677 <species id="M_succ_e" name="M_Succinate_C4H4O4" compartment="Extra_organism" charge="-2" boundaryCondition="false"/>
678 <species id="M_succoa_c" name="M_Succinyl_CoA_C25H35N7O19P3S" compartment="Cytosol" charge="-5" boundaryCondition="false"/>
679 <species id="M_sucglu_c" name="M_N2_Succinyl_L_glutamate_C9H10NO7" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
680 <species id="M_sucgsa_c" name="M_N2_Succinyl_L_glutamate_5_semialdehyde_C9H11NO6" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
681 <species id="M_suchms_c" name="M_O_Succinyl_L_homoserine_C8H12NO6" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
682 <species id="M_sucorn_c" name="M_N2_Succinyl_L_ornithine_C9H15N2O5" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
683 <species id="M_sucr_e" name="M_Sucrose_C12H22O11" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
684 <species id="M_sucsal_c" name="M_Succinic_semialdehyde_C4H5O3" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
685 <species id="M_tag6p_D_c" name="M_D_Tagatose_6_phosphate_C6H11O9P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
686 <species id="M_tagdp_D_c" name="M_D_Tagatose_1_6_biphosphate_C6H10O12P2" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
687 <species id="M_tagur_c" name="M_D_Tagaturonate_C6H9O7" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
688 <species id="M_tartr_L_c" name="M_L_tartrate_C4H4O6" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
689 <species id="M_tartr_L_e" name="M_L_tartrate_C4H4O6" compartment="Extra_organism" charge="-2" boundaryCondition="false"/>
690 <species id="M_taur_c" name="M_Taurine_C2H7NO3S" compartment="Cytosol" charge="0" boundaryCondition="false"/>
691 <species id="M_taur_e" name="M_Taurine_C2H7NO3S" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
692 <species id="M_tcynt_c" name="M_Thiocyanate_CNS" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
693 <species id="M_tdeACP_c" name="M_cis_tetradec_7_enoyl_acyl_carrier_protein__n_C141__C25H45N2O8PRS" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
694 <species id="M_thdp_c" name="M_2_3_4_5_Tetrahydrodipicolinate_C7H7NO4" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
695 <species id="M_thf_c" name="M_5_6_7_8_Tetrahydrofolate_C19H21N7O6" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
696 <species id="M_thm_c" name="M_Thiamin_C12H17N4OS" compartment="Cytosol" charge="1" boundaryCondition="false"/>
697 <species id="M_thm_e" name="M_Thiamin_C12H17N4OS" compartment="Extra_organism" charge="1" boundaryCondition="false"/>
698 <species id="M_thmmp_c" name="M_Thiamin_monophosphate_C12H16N4O4PS" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
699 <species id="M_thmpp_c" name="M_Thiamine_diphosphate_C12H16N4O7P2S" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
700 <species id="M_thr_L_c" name="M_L_Threonine_C4H9NO3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
701 <species id="M_thr_L_e" name="M_L_Threonine_C4H9NO3" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
702 <species id="M_thym_c" name="M_Thymine_C5H6N2O2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
703 <species id="M_thymd_c" name="M_Thymidine_C10H14N2O5" compartment="Cytosol" charge="0" boundaryCondition="false"/>
704 <species id="M_thymd_e" name="M_Thymidine_C10H14N2O5" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
705 <species id="M_tma_c" name="M_trimethylamine_C3H10N" compartment="Cytosol" charge="1" boundaryCondition="false"/>
706 <species id="M_tma_e" name="M_trimethylamine_C3H10N" compartment="Extra_organism" charge="1" boundaryCondition="false"/>
707 <species id="M_tmao_c" name="M_Trimethylamine_N_oxide_C3H9NO" compartment="Cytosol" charge="0" boundaryCondition="false"/>
708 <species id="M_tmao_e" name="M_Trimethylamine_N_oxide_C3H9NO" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
709 <species id="M_trdox_c" name="M_Oxidized_thioredoxin_X" compartment="Cytosol" charge="0" boundaryCondition="false"/>
710 <species id="M_trdrd_c" name="M_Reduced_thioredoxin_XH2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
711 <species id="M_tre6p_c" name="M_alpha_alpha__Trehalose_6_phosphate_C12H21O14P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
712 <species id="M_tre_c" name="M_Trehalose_C12H22O11" compartment="Cytosol" charge="0" boundaryCondition="false"/>
713 <species id="M_tre_e" name="M_Trehalose_C12H22O11" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
714 <species id="M_trnaglu_c" name="M_tRNA__Glu__R" compartment="Cytosol" charge="0" boundaryCondition="false"/>
715 <species id="M_trp_L_c" name="M_L_Tryptophan_C11H12N2O2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
716 <species id="M_trp_L_e" name="M_L_Tryptophan_C11H12N2O2" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
717 <species id="M_tsul_c" name="M_Thiosulfate_O3S2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
718 <species id="M_tsul_e" name="M_Thiosulfate_O3S2" compartment="Extra_organism" charge="-2" boundaryCondition="false"/>
719 <species id="M_ttdca_c" name="M_tetradecanoate__n_C140__C14H27O2" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
720 <species id="M_ttdca_e" name="M_tetradecanoate__n_C140__C14H27O2" compartment="Extra_organism" charge="-1" boundaryCondition="false"/>
721 <species id="M_ttdcea_c" name="M_tetradecenoate__n_C141__C14H25O2" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
722 <species id="M_tyr_L_c" name="M_L_Tyrosine_C9H11NO3" compartment="Cytosol" charge="0" boundaryCondition="false"/>
723 <species id="M_tyr_L_e" name="M_L_Tyrosine_C9H11NO3" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
724 <species id="M_u23ga_c" name="M_UDP_2_3_bis_3_hydroxytetradecanoyl_glucosamine_C43H75N3O20P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
725 <species id="M_u3aga_c" name="M_UDP_3_O__3_hydroxytetradecanoyl__N_acetylglucosamine_C31H51N3O19P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
726 <species id="M_u3hga_c" name="M_UDP_3_O__3_hydroxytetradecanoyl__D_glucosamine_C29H50N3O18P2" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
727 <species id="M_uaagmda_c" name="M_Undecaprenyl_diphospho_N_acetylmuramoyl__N_acetylglucosamine__L_ala_D_glu_meso_2_6_diaminopimeloyl_D_ala_D_ala_C95H152N8O28P2" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
728 <species id="M_uaccg_c" name="M_UDP_N_acetyl_3_O__1_carboxyvinyl__D_glucosamine_C20H26N3O19P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
729 <species id="M_uacgam_c" name="M_UDP_N_acetyl_D_glucosamine_C17H25N3O17P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
730 <species id="M_uacmam_c" name="M_UDP_N_acetyl_D_mannosamine_C17H25N3O17P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
731 <species id="M_uacmamu_c" name="M_UDP_N_acetyl_D_mannosaminouronate_C17H22N3O18P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
732 <species id="M_uagmda_c" name="M_Undecaprenyl_diphospho_N_acetylmuramoyl_L_alanyl_D_glutamyl_meso_2_6_diaminopimeloyl_D_alanyl_D_alanine_C87H139N7O23P2" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
733 <species id="M_uama_c" name="M_UDP_N_acetylmuramoyl_L_alanine_C23H33N4O20P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
734 <species id="M_uamag_c" name="M_UDP_N_acetylmuramoyl_L_alanyl_D_glutamate_C28H39N5O23P2" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
735 <species id="M_uamr_c" name="M_UDP_N_acetylmuramate_C20H28N3O19P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
736 <species id="M_udcpdp_c" name="M_Undecaprenyl_diphosphate_C55H89O7P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
737 <species id="M_udcpp_c" name="M_Undecaprenyl_phosphate_C55H89O4P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
738 <species id="M_udp_c" name="M_UDP_C9H11N2O12P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
739 <species id="M_udpg_c" name="M_UDPglucose_C15H22N2O17P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
740 <species id="M_udpgal_c" name="M_UDPgalactose_C15H22N2O17P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
741 <species id="M_udpgalfur_c" name="M_UDP_D_galacto_1_4_furanose_C15H22N2O17P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
742 <species id="M_udpglcur_c" name="M_UDP_D_glucuronate_C15H19N2O18P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
743 <species id="M_ugmd_c" name="M_UDP_N_acetylmuramoyl_L_alanyl_D_gamma_glutamyl_meso_2_6_diaminopimelate_C35H51N7O26P2" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
744 <species id="M_ugmda_c" name="M_UDP_N_acetylmuramoyl_L_alanyl_D_glutamyl_meso_2_6_diaminopimeloyl_D_alanyl_D_alanine_C41H61N9O28P2" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
745 <species id="M_ump_c" name="M_UMP_C9H11N2O9P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
746 <species id="M_unaga_c" name="M_Undecaprenyl_diphospho_N_acetyl_glucosamine_C63H103NO12P2" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
747 <species id="M_unagamu_c" name="M_Undecaprenyl_diphospho_N_acetylglucosamine_N_acetylmannosaminuronate_C71H113N2O18P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
748 <species id="M_unagamuf_c" name="M_Undecaprenyl_diphospho_N_acetylglucosamine_N_acetylmannosaminuronate_N_acetamido_4_6_dideoxy_D_galactose_C79H126N3O22P2" compartment="Cytosol" charge="-3" boundaryCondition="false"/>
749 <species id="M_uppg3_c" name="M_Uroporphyrinogen_III_C40H36N4O16" compartment="Cytosol" charge="-8" boundaryCondition="false"/>
750 <species id="M_ura_c" name="M_Uracil_C4H4N2O2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
751 <species id="M_ura_e" name="M_Uracil_C4H4N2O2" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
752 <species id="M_urdglyc_c" name="M_____Ureidoglycolate_C3H5N2O4" compartment="Cytosol" charge="-1" boundaryCondition="false"/>
753 <species id="M_urea_c" name="M_Urea_CH4N2O" compartment="Cytosol" charge="0" boundaryCondition="false"/>
754 <species id="M_urea_e" name="M_Urea_CH4N2O" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
755 <species id="M_uri_c" name="M_Uridine_C9H12N2O6" compartment="Cytosol" charge="0" boundaryCondition="false"/>
756 <species id="M_uri_e" name="M_Uridine_C9H12N2O6" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
757 <species id="M_utp_c" name="M_UTP_C9H11N2O15P3" compartment="Cytosol" charge="-4" boundaryCondition="false"/>
758 <species id="M_val_L_c" name="M_L_Valine_C5H11NO2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
759 <species id="M_val_L_e" name="M_L_Valine_C5H11NO2" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
760 <species id="M_xan_c" name="M_Xanthine_C5H4N4O2" compartment="Cytosol" charge="0" boundaryCondition="false"/>
761 <species id="M_xan_e" name="M_Xanthine_C5H4N4O2" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
762 <species id="M_xmp_c" name="M_Xanthosine_5__phosphate_C10H11N4O9P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
763 <species id="M_xtsn_c" name="M_Xanthosine_C10H12N4O6" compartment="Cytosol" charge="0" boundaryCondition="false"/>
764 <species id="M_xtsn_e" name="M_Xanthosine_C10H12N4O6" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
765 <species id="M_xu5p_D_c" name="M_D_Xylulose_5_phosphate_C5H9O8P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
766 <species id="M_xu5p_L_c" name="M_L_Xylulose_5_phosphate_C5H9O8P" compartment="Cytosol" charge="-2" boundaryCondition="false"/>
767 <species id="M_xyl_D_c" name="M_D_Xylose_C5H10O5" compartment="Cytosol" charge="0" boundaryCondition="false"/>
768 <species id="M_xyl_D_e" name="M_D_Xylose_C5H10O5" compartment="Extra_organism" charge="0" boundaryCondition="false"/>
769 <species id="M_xylu_D_c" name="M_D_Xylulose_C5H10O5" compartment="Cytosol" charge="0" boundaryCondition="false"/>
770 <species id="M_12ppd_S_b" name="M__S__Propane_1_2_diol_C3H8O2" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
771 <species id="M_15dap_b" name="M_1_5_Diaminopentane_C5H16N2" compartment="Extra_organism" charge="2" boundaryCondition="true"/>
772 <species id="M_26dap_M_b" name="M_meso_2_6_Diaminoheptanedioate_C7H14N2O4" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
773 <species id="M_2ddglcn_b" name="M_2_Dehydro_3_deoxy_D_gluconate_C6H9O6" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
774 <species id="M_3hcinnm_b" name="M_3_hydroxycinnamic_acid_C9H7O3" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
775 <species id="M_3hpppn_b" name="M_3__3_hydroxy_phenyl_propionate_C9H9O3" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
776 <species id="M_4abut_b" name="M_4_Aminobutanoate_C4H9NO2" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
777 <species id="M_ac_b" name="M_Acetate_C2H3O2" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
778 <species id="M_acac_b" name="M_Acetoacetate_C4H5O3" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
779 <species id="M_acald_b" name="M_Acetaldehyde_C2H4O" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
780 <species id="M_acgam_b" name="M_N_Acetyl_D_glucosamine_C8H15NO6" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
781 <species id="M_acmana_b" name="M_N_Acetyl_D_mannosamine_C8H15NO6" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
782 <species id="M_acnam_b" name="M_N_Acetylneuraminate_C11H18NO9" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
783 <species id="M_ade_b" name="M_Adenine_C5H5N5" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
784 <species id="M_adn_b" name="M_Adenosine_C10H13N5O4" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
785 <species id="M_akg_b" name="M_2_Oxoglutarate_C5H4O5" compartment="Extra_organism" charge="-2" boundaryCondition="true"/>
786 <species id="M_ala_D_b" name="M_D_Alanine_C3H7NO2" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
787 <species id="M_ala_L_b" name="M_L_Alanine_C3H7NO2" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
788 <species id="M_alltn_b" name="M_Allantoin_C4H6N4O3" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
789 <species id="M_amp_b" name="M_AMP_C10H12N5O7P" compartment="Extra_organism" charge="-2" boundaryCondition="true"/>
790 <species id="M_arab_L_b" name="M_L_Arabinose_C5H10O5" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
791 <species id="M_arg_L_b" name="M_L_Arginine_C6H15N4O2" compartment="Extra_organism" charge="1" boundaryCondition="true"/>
792 <species id="M_asn_L_b" name="M_L_Asparagine_C4H8N2O3" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
793 <species id="M_asp_L_b" name="M_L_Aspartate_C4H6NO4" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
794 <species id="M_but_b" name="M_Butyrate__n_C40__C4H7O2" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
795 <species id="M_cbl1_b" name="M_Cob_I_alamin_C62H88CoN13O14P" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
796 <species id="M_chol_b" name="M_Choline_C5H14NO" compartment="Extra_organism" charge="1" boundaryCondition="true"/>
797 <species id="M_cit_b" name="M_Citrate_C6H5O7" compartment="Extra_organism" charge="-3" boundaryCondition="true"/>
798 <species id="M_co2_b" name="M_CO2_CO2" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
799 <species id="M_crn_b" name="M_L_Carnitine_C7H15NO3" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
800 <species id="M_csn_b" name="M_Cytosine_C4H5N3O" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
801 <species id="M_cynt_b" name="M_Cyanate_CNO" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
802 <species id="M_cys_L_b" name="M_L_Cysteine_C3H7NO2S" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
803 <species id="M_cytd_b" name="M_Cytidine_C9H13N3O5" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
804 <species id="M_dad_2_b" name="M_Deoxyadenosine_C10H13N5O3" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
805 <species id="M_dcyt_b" name="M_Deoxycytidine_C9H13N3O4" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
806 <species id="M_dgsn_b" name="M_Deoxyguanosine_C10H13N5O4" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
807 <species id="M_dha_b" name="M_Dihydroxyacetone_C3H6O3" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
808 <species id="M_din_b" name="M_Deoxyinosine_C10H12N4O4" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
809 <species id="M_dms_b" name="M_Dimethyl_sulfide_C2H6S" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
810 <species id="M_dmso_b" name="M_Dimethyl_sulfoxide_C2H6OS" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
811 <species id="M_duri_b" name="M_Deoxyuridine_C9H12N2O5" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
812 <species id="M_etoh_b" name="M_Ethanol_C2H6O" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
813 <species id="M_fe2_b" name="M_Fe2_Fe" compartment="Extra_organism" charge="2" boundaryCondition="true"/>
814 <species id="M_for_b" name="M_Formate_CH1O2" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
815 <species id="M_fru_b" name="M_D_Fructose_C6H12O6" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
816 <species id="M_fuc1p_L_b" name="M_L_Fucose_1_phosphate_C6H11O8P" compartment="Extra_organism" charge="-2" boundaryCondition="true"/>
817 <species id="M_fuc_L_b" name="M_L_Fucose_C6H12O5" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
818 <species id="M_fum_b" name="M_Fumarate_C4H2O4" compartment="Extra_organism" charge="-2" boundaryCondition="true"/>
819 <species id="M_g6p_b" name="M_D_Glucose_6_phosphate_C6H11O9P" compartment="Extra_organism" charge="-2" boundaryCondition="true"/>
820 <species id="M_gal_b" name="M_D_Galactose_C6H12O6" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
821 <species id="M_galct_D_b" name="M_D_Galactarate_C6H8O8" compartment="Extra_organism" charge="-2" boundaryCondition="true"/>
822 <species id="M_galctn_D_b" name="M_D_Galactonate_C6H11O7" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
823 <species id="M_galt_b" name="M_Galactitol_C6H14O6" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
824 <species id="M_galur_b" name="M_D_Galacturonate_C6H9O7" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
825 <species id="M_gam_b" name="M_D_Glucosamine_C6H14NO5" compartment="Extra_organism" charge="1" boundaryCondition="true"/>
826 <species id="M_gbbtn_b" name="M_gamma_butyrobetaine_C7H15NO2" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
827 <species id="M_glc_D_b" name="M_D_Glucose_C6H12O6" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
828 <species id="M_glcn_b" name="M_D_Gluconate_C6H11O7" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
829 <species id="M_glcr_b" name="M_D_Glucarate_C6H8O8" compartment="Extra_organism" charge="-2" boundaryCondition="true"/>
830 <species id="M_glcur_b" name="M_D_Glucuronate_C6H9O7" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
831 <species id="M_gln_L_b" name="M_L_Glutamine_C5H10N2O3" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
832 <species id="M_glu_L_b" name="M_L_Glutamate_C5H8NO4" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
833 <species id="M_gly_b" name="M_Glycine_C2H5NO2" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
834 <species id="M_glyald_b" name="M_D_Glyceraldehyde_C3H6O3" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
835 <species id="M_glyb_b" name="M_Glycine_betaine_C5H11NO2" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
836 <species id="M_glyc3p_b" name="M_Glycerol_3_phosphate_C3H7O6P" compartment="Extra_organism" charge="-2" boundaryCondition="true"/>
837 <species id="M_glyc_b" name="M_Glycerol_C3H8O3" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
838 <species id="M_glyclt_b" name="M_Glycolate_C2H3O3" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
839 <species id="M_gsn_b" name="M_Guanosine_C10H13N5O5" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
840 <species id="M_gua_b" name="M_Guanine_C5H5N5O" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
841 <species id="M_h2o_b" name="M_H2O_H2O" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
842 <species id="M_h_b" name="M_H_H" compartment="Extra_organism" charge="1" boundaryCondition="true"/>
843 <species id="M_hdca_b" name="M_Hexadecanoate__n_C160__C16H31O2" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
844 <species id="M_his_L_b" name="M_L_Histidine_C6H9N3O2" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
845 <species id="M_hxan_b" name="M_Hypoxanthine_C5H4N4O" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
846 <species id="M_idon_L_b" name="M_L_Idonate_C6H11O7" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
847 <species id="M_ile_L_b" name="M_L_Isoleucine_C6H13NO2" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
848 <species id="M_indole_b" name="M_Indole_C8H7N" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
849 <species id="M_ins_b" name="M_Inosine_C10H12N4O5" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
850 <species id="M_k_b" name="M_potassium_K" compartment="Extra_organism" charge="1" boundaryCondition="true"/>
851 <species id="M_lac_D_b" name="M_D_Lactate_C3H5O3" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
852 <species id="M_lac_L_b" name="M_L_Lactate_C3H5O3" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
853 <species id="M_lcts_b" name="M_Lactose_C12H22O11" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
854 <species id="M_leu_L_b" name="M_L_Leucine_C6H13NO2" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
855 <species id="M_lys_L_b" name="M_L_Lysine_C6H15N2O2" compartment="Extra_organism" charge="1" boundaryCondition="true"/>
856 <species id="M_mal_L_b" name="M_L_Malate_C4H4O5" compartment="Extra_organism" charge="-2" boundaryCondition="true"/>
857 <species id="M_malt_b" name="M_Maltose_C12H22O11" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
858 <species id="M_malthx_b" name="M_Maltohexaose_C36H62O31" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
859 <species id="M_maltpt_b" name="M_Maltopentaose_C30H52O26" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
860 <species id="M_malttr_b" name="M_Maltotriose_C18H32O16" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
861 <species id="M_maltttr_b" name="M_Maltotetraose_C24H42O21" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
862 <species id="M_man6p_b" name="M_D_Mannose_6_phosphate_C6H11O9P" compartment="Extra_organism" charge="-2" boundaryCondition="true"/>
863 <species id="M_man_b" name="M_D_Mannose_C6H12O6" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
864 <species id="M_melib_b" name="M_Melibiose_C12H22O11" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
865 <species id="M_met_D_b" name="M_D_Methionine_C5H10NO2S" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
866 <species id="M_met_L_b" name="M_L_Methionine_C5H11NO2S" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
867 <species id="M_mnl_b" name="M_D_Mannitol_C6H14O6" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
868 <species id="M_na1_b" name="M_Sodium_Na" compartment="Extra_organism" charge="1" boundaryCondition="true"/>
869 <species id="M_nac_b" name="M_Nicotinate_C6H4NO2" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
870 <species id="M_nad_b" name="M_Nicotinamide_adenine_dinucleotide_C21H26N7O14P2" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
871 <species id="M_nh4_b" name="M_Ammonium_H4N" compartment="Extra_organism" charge="1" boundaryCondition="true"/>
872 <species id="M_nmn_b" name="M_NMN_C11H14N2O8P" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
873 <species id="M_no2_b" name="M_Nitrite_NO2" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
874 <species id="M_no3_b" name="M_Nitrate_NO3" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
875 <species id="M_o2_b" name="M_O2_O2" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
876 <species id="M_ocdca_b" name="M_octadecanoate__n_C180__C18H35O2" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
877 <species id="M_orn_b" name="M_Ornithine_C5H13N2O2" compartment="Extra_organism" charge="1" boundaryCondition="true"/>
878 <species id="M_phe_L_b" name="M_L_Phenylalanine_C9H11NO2" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
879 <species id="M_pi_b" name="M_Phosphate_HO4P" compartment="Extra_organism" charge="-2" boundaryCondition="true"/>
880 <species id="M_pnto_R_b" name="M__R__Pantothenate_C9H16NO5" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
881 <species id="M_pppn_b" name="M_Phenylpropanoate_C9H9O2" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
882 <species id="M_pro_L_b" name="M_L_Proline_C5H9NO2" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
883 <species id="M_ptrc_b" name="M_Putrescine_C4H14N2" compartment="Extra_organism" charge="2" boundaryCondition="true"/>
884 <species id="M_pyr_b" name="M_Pyruvate_C3H3O3" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
885 <species id="M_rib_D_b" name="M_D_Ribose_C5H10O5" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
886 <species id="M_rmn_b" name="M_L_Rhamnose_C6H12O5" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
887 <species id="M_sbt_D_b" name="M_D_Sorbitol_C6H14O6" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
888 <species id="M_ser_D_b" name="M_D_Serine_C3H7NO3" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
889 <species id="M_ser_L_b" name="M_L_Serine_C3H7NO3" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
890 <species id="M_so4_b" name="M_Sulfate_O4S" compartment="Extra_organism" charge="-2" boundaryCondition="true"/>
891 <species id="M_spmd_b" name="M_Spermidine_C7H22N3" compartment="Extra_organism" charge="3" boundaryCondition="true"/>
892 <species id="M_succ_b" name="M_Succinate_C4H4O4" compartment="Extra_organism" charge="-2" boundaryCondition="true"/>
893 <species id="M_sucr_b" name="M_Sucrose_C12H22O11" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
894 <species id="M_tartr_L_b" name="M_L_tartrate_C4H4O6" compartment="Extra_organism" charge="-2" boundaryCondition="true"/>
895 <species id="M_taur_b" name="M_Taurine_C2H7NO3S" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
896 <species id="M_thm_b" name="M_Thiamin_C12H17N4OS" compartment="Extra_organism" charge="1" boundaryCondition="true"/>
897 <species id="M_thr_L_b" name="M_L_Threonine_C4H9NO3" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
898 <species id="M_thymd_b" name="M_Thymidine_C10H14N2O5" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
899 <species id="M_tma_b" name="M_trimethylamine_C3H10N" compartment="Extra_organism" charge="1" boundaryCondition="true"/>
900 <species id="M_tmao_b" name="M_Trimethylamine_N_oxide_C3H9NO" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
901 <species id="M_tre_b" name="M_Trehalose_C12H22O11" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
902 <species id="M_trp_L_b" name="M_L_Tryptophan_C11H12N2O2" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
903 <species id="M_tsul_b" name="M_Thiosulfate_O3S2" compartment="Extra_organism" charge="-2" boundaryCondition="true"/>
904 <species id="M_ttdca_b" name="M_tetradecanoate__n_C140__C14H27O2" compartment="Extra_organism" charge="-1" boundaryCondition="true"/>
905 <species id="M_tyr_L_b" name="M_L_Tyrosine_C9H11NO3" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
906 <species id="M_ura_b" name="M_Uracil_C4H4N2O2" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
907 <species id="M_urea_b" name="M_Urea_CH4N2O" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
908 <species id="M_uri_b" name="M_Uridine_C9H12N2O6" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
909 <species id="M_val_L_b" name="M_L_Valine_C5H11NO2" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
910 <species id="M_xan_b" name="M_Xanthine_C5H4N4O2" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
911 <species id="M_xtsn_b" name="M_Xanthosine_C10H12N4O6" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
912 <species id="M_xyl_D_b" name="M_D_Xylose_C5H10O5" compartment="Extra_organism" charge="0" boundaryCondition="true"/>
913 </listOfSpecies>
914 <listOfReactions>
915 <reaction id="R_12PPDt" name="R_S_Propane_1_2_diol_facilitated_transport" reversible="true">
916 <notes>
917 <html:p>GENE_ASSOCIATION: </html:p>
918 <html:p>PROTEIN_ASSOCIATION: </html:p>
919 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
920 <html:p>PROTEIN_CLASS: </html:p>
921 </notes>
922 <listOfReactants>
923 <speciesReference species="M_12ppd_S_e" stoichiometry="1.000000"/>
924 </listOfReactants>
925 <listOfProducts>
926 <speciesReference species="M_12ppd_S_c" stoichiometry="1.000000"/>
927 </listOfProducts>
928 </reaction>
929 <reaction id="R_2DGLCNRx" name="R_2_dehydro_D_gluconate_reductase__NADH_" reversible="false">
930 <notes>
931 <html:p>GENE_ASSOCIATION: b3553</html:p>
932 <html:p>PROTEIN_ASSOCIATION: YiaE</html:p>
933 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
934 <html:p>PROTEIN_CLASS: </html:p>
935 </notes>
936 <listOfReactants>
937 <speciesReference species="M_2dhglcn_c" stoichiometry="1.000000"/>
938 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
939 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
940 </listOfReactants>
941 <listOfProducts>
942 <speciesReference species="M_glcn_c" stoichiometry="1.000000"/>
943 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
944 </listOfProducts>
945 </reaction>
946 <reaction id="R_2DGLCNRy" name="R_2_dehydro_D_gluconate_reductase__NADPH_" reversible="false">
947 <notes>
948 <html:p>GENE_ASSOCIATION: b3553</html:p>
949 <html:p>PROTEIN_ASSOCIATION: YiaE</html:p>
950 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
951 <html:p>PROTEIN_CLASS: 1.1.1.215</html:p>
952 </notes>
953 <listOfReactants>
954 <speciesReference species="M_2dhglcn_c" stoichiometry="1.000000"/>
955 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
956 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
957 </listOfReactants>
958 <listOfProducts>
959 <speciesReference species="M_glcn_c" stoichiometry="1.000000"/>
960 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
961 </listOfProducts>
962 </reaction>
963 <reaction id="R_2DGULRx" name="R_2_dehydro_L_gulonate_reductase__NADH_" reversible="false">
964 <notes>
965 <html:p>GENE_ASSOCIATION: b3553</html:p>
966 <html:p>PROTEIN_ASSOCIATION: YiaE</html:p>
967 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
968 <html:p>PROTEIN_CLASS: </html:p>
969 </notes>
970 <listOfReactants>
971 <speciesReference species="M_2dhguln_c" stoichiometry="1.000000"/>
972 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
973 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
974 </listOfReactants>
975 <listOfProducts>
976 <speciesReference species="M_idon_L_c" stoichiometry="1.000000"/>
977 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
978 </listOfProducts>
979 </reaction>
980 <reaction id="R_2DGULRy" name="R_2_dehydro_L_gulonate_reductase__NADPH_" reversible="false">
981 <notes>
982 <html:p>GENE_ASSOCIATION: b3553</html:p>
983 <html:p>PROTEIN_ASSOCIATION: YiaE</html:p>
984 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
985 <html:p>PROTEIN_CLASS: </html:p>
986 </notes>
987 <listOfReactants>
988 <speciesReference species="M_2dhguln_c" stoichiometry="1.000000"/>
989 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
990 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
991 </listOfReactants>
992 <listOfProducts>
993 <speciesReference species="M_idon_L_c" stoichiometry="1.000000"/>
994 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
995 </listOfProducts>
996 </reaction>
997 <reaction id="R_3HCINNMH" name="R_3_hydroxycinnamate_hydroxylase" reversible="false">
998 <notes>
999 <html:p>GENE_ASSOCIATION: b0347</html:p>
1000 <html:p>PROTEIN_ASSOCIATION: MhpA</html:p>
1001 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
1002 <html:p>PROTEIN_CLASS: </html:p>
1003 </notes>
1004 <listOfReactants>
1005 <speciesReference species="M_3hcinnm_c" stoichiometry="1.000000"/>
1006 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1007 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
1008 <speciesReference species="M_o2_c" stoichiometry="1.000000"/>
1009 </listOfReactants>
1010 <listOfProducts>
1011 <speciesReference species="M_dhcinnm_c" stoichiometry="1.000000"/>
1012 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
1013 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
1014 </listOfProducts>
1015 </reaction>
1016 <reaction id="R_3HPPPNH" name="R_3__3_hydroxy_phenyl_propionate_hydroxylase" reversible="false">
1017 <notes>
1018 <html:p>GENE_ASSOCIATION: b0347</html:p>
1019 <html:p>PROTEIN_ASSOCIATION: MhpA</html:p>
1020 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
1021 <html:p>PROTEIN_CLASS: </html:p>
1022 </notes>
1023 <listOfReactants>
1024 <speciesReference species="M_3hpppn_c" stoichiometry="1.000000"/>
1025 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1026 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
1027 <speciesReference species="M_o2_c" stoichiometry="1.000000"/>
1028 </listOfReactants>
1029 <listOfProducts>
1030 <speciesReference species="M_dhpppn_c" stoichiometry="1.000000"/>
1031 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
1032 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
1033 </listOfProducts>
1034 </reaction>
1035 <reaction id="R_4HTHRS" name="R_4_Hydroxy_L_threonine_synthase" reversible="false">
1036 <notes>
1037 <html:p>GENE_ASSOCIATION: b0004</html:p>
1038 <html:p>PROTEIN_ASSOCIATION: ThrC</html:p>
1039 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
1040 <html:p>PROTEIN_CLASS: </html:p>
1041 </notes>
1042 <listOfReactants>
1043 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
1044 <speciesReference species="M_phthr_c" stoichiometry="1.000000"/>
1045 </listOfReactants>
1046 <listOfProducts>
1047 <speciesReference species="M_4hthr_c" stoichiometry="1.000000"/>
1048 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
1049 </listOfProducts>
1050 </reaction>
1051 <reaction id="R_5DGLCNR" name="R_5_dehydro_D_gluconate_reductase" reversible="true">
1052 <notes>
1053 <html:p>GENE_ASSOCIATION: b4266</html:p>
1054 <html:p>PROTEIN_ASSOCIATION: IdnO</html:p>
1055 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
1056 <html:p>PROTEIN_CLASS: 1.1.1.69</html:p>
1057 </notes>
1058 <listOfReactants>
1059 <speciesReference species="M_5dglcn_c" stoichiometry="1.000000"/>
1060 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1061 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
1062 </listOfReactants>
1063 <listOfProducts>
1064 <speciesReference species="M_glcn_c" stoichiometry="1.000000"/>
1065 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
1066 </listOfProducts>
1067 </reaction>
1068 <reaction id="R_A5PISO" name="R_arabinose_5_phosphate_isomerase" reversible="true">
1069 <notes>
1070 <html:p>GENE_ASSOCIATION: </html:p>
1071 <html:p>PROTEIN_ASSOCIATION: </html:p>
1072 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
1073 <html:p>PROTEIN_CLASS: 5.3.1.13</html:p>
1074 </notes>
1075 <listOfReactants>
1076 <speciesReference species="M_ru5p_D_c" stoichiometry="1.000000"/>
1077 </listOfReactants>
1078 <listOfProducts>
1079 <speciesReference species="M_ara5p_c" stoichiometry="1.000000"/>
1080 </listOfProducts>
1081 </reaction>
1082 <reaction id="R_AACPS1" name="R_acyl_acyl_carrier_protein_synthetase__n_C140_" reversible="false">
1083 <notes>
1084 <html:p>GENE_ASSOCIATION: b2836</html:p>
1085 <html:p>PROTEIN_ASSOCIATION: Aas</html:p>
1086 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
1087 <html:p>PROTEIN_CLASS: 6.2.1.20</html:p>
1088 </notes>
1089 <listOfReactants>
1090 <speciesReference species="M_ACP_c" stoichiometry="1.000000"/>
1091 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
1092 <speciesReference species="M_ttdca_c" stoichiometry="1.000000"/>
1093 </listOfReactants>
1094 <listOfProducts>
1095 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
1096 <speciesReference species="M_myrsACP_c" stoichiometry="1.000000"/>
1097 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
1098 </listOfProducts>
1099 </reaction>
1100 <reaction id="R_AACPS2" name="R_acyl_acyl_carrier_protein_synthetase___n_C141_" reversible="false">
1101 <notes>
1102 <html:p>GENE_ASSOCIATION: b2836</html:p>
1103 <html:p>PROTEIN_ASSOCIATION: Aas</html:p>
1104 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
1105 <html:p>PROTEIN_CLASS: 6.2.1.20</html:p>
1106 </notes>
1107 <listOfReactants>
1108 <speciesReference species="M_ACP_c" stoichiometry="1.000000"/>
1109 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
1110 <speciesReference species="M_ttdcea_c" stoichiometry="1.000000"/>
1111 </listOfReactants>
1112 <listOfProducts>
1113 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
1114 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
1115 <speciesReference species="M_tdeACP_c" stoichiometry="1.000000"/>
1116 </listOfProducts>
1117 </reaction>
1118 <reaction id="R_AACPS3" name="R_acyl_acyl_carrier_protein_synthetase___n_C160_" reversible="false">
1119 <notes>
1120 <html:p>GENE_ASSOCIATION: b2836</html:p>
1121 <html:p>PROTEIN_ASSOCIATION: Aas</html:p>
1122 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
1123 <html:p>PROTEIN_CLASS: 6.2.1.20</html:p>
1124 </notes>
1125 <listOfReactants>
1126 <speciesReference species="M_ACP_c" stoichiometry="1.000000"/>
1127 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
1128 <speciesReference species="M_hdca_c" stoichiometry="1.000000"/>
1129 </listOfReactants>
1130 <listOfProducts>
1131 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
1132 <speciesReference species="M_palmACP_c" stoichiometry="1.000000"/>
1133 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
1134 </listOfProducts>
1135 </reaction>
1136 <reaction id="R_AACPS4" name="R_acyl_acyl_carrier_protein_synthetase___n_C161_" reversible="false">
1137 <notes>
1138 <html:p>GENE_ASSOCIATION: b2836</html:p>
1139 <html:p>PROTEIN_ASSOCIATION: Aas</html:p>
1140 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
1141 <html:p>PROTEIN_CLASS: 6.2.1.20</html:p>
1142 </notes>
1143 <listOfReactants>
1144 <speciesReference species="M_ACP_c" stoichiometry="1.000000"/>
1145 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
1146 <speciesReference species="M_hdcea_c" stoichiometry="1.000000"/>
1147 </listOfReactants>
1148 <listOfProducts>
1149 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
1150 <speciesReference species="M_hdeACP_c" stoichiometry="1.000000"/>
1151 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
1152 </listOfProducts>
1153 </reaction>
1154 <reaction id="R_AACPS5" name="R_acyl_acyl_carrier_protein_synthetase___n_C181_" reversible="false">
1155 <notes>
1156 <html:p>GENE_ASSOCIATION: b2836</html:p>
1157 <html:p>PROTEIN_ASSOCIATION: Aas</html:p>
1158 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
1159 <html:p>PROTEIN_CLASS: 6.2.1.20</html:p>
1160 </notes>
1161 <listOfReactants>
1162 <speciesReference species="M_ACP_c" stoichiometry="1.000000"/>
1163 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
1164 <speciesReference species="M_ocdcea_c" stoichiometry="1.000000"/>
1165 </listOfReactants>
1166 <listOfProducts>
1167 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
1168 <speciesReference species="M_octeACP_c" stoichiometry="1.000000"/>
1169 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
1170 </listOfProducts>
1171 </reaction>
1172 <reaction id="R_AADDGT" name="R_dTDP_N_4_acetamido_4_6_dideoxy_D_galactose_transferase" reversible="false">
1173 <notes>
1174 <html:p>GENE_ASSOCIATION: b3793</html:p>
1175 <html:p>PROTEIN_ASSOCIATION: WecF</html:p>
1176 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
1177 <html:p>PROTEIN_CLASS: </html:p>
1178 </notes>
1179 <listOfReactants>
1180 <speciesReference species="M_dtdp4aaddg_c" stoichiometry="1.000000"/>
1181 <speciesReference species="M_unagamu_c" stoichiometry="1.000000"/>
1182 </listOfReactants>
1183 <listOfProducts>
1184 <speciesReference species="M_dtdp_c" stoichiometry="1.000000"/>
1185 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1186 <speciesReference species="M_unagamuf_c" stoichiometry="1.000000"/>
1187 </listOfProducts>
1188 </reaction>
1189 <reaction id="R_AB6PGH" name="R_Arbutin_6_phosphate_glucohydrolase" reversible="false">
1190 <notes>
1191 <html:p>GENE_ASSOCIATION: b2901</html:p>
1192 <html:p>PROTEIN_ASSOCIATION: BglA</html:p>
1193 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
1194 <html:p>PROTEIN_CLASS: 3.2.1.86</html:p>
1195 </notes>
1196 <listOfReactants>
1197 <speciesReference species="M_arbt6p_c" stoichiometry="1.000000"/>
1198 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
1199 </listOfReactants>
1200 <listOfProducts>
1201 <speciesReference species="M_g6p_c" stoichiometry="1.000000"/>
1202 <speciesReference species="M_hqn_c" stoichiometry="1.000000"/>
1203 </listOfProducts>
1204 </reaction>
1205 <reaction id="R_ABTA" name="R_4_aminobutyrate_transaminase" reversible="false">
1206 <notes>
1207 <html:p>GENE_ASSOCIATION: ( b2662 or b1302 )</html:p>
1208 <html:p>PROTEIN_ASSOCIATION: ( GabT ) or ( PuuE )</html:p>
1209 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
1210 <html:p>PROTEIN_CLASS: 2.6.1.19</html:p>
1211 </notes>
1212 <listOfReactants>
1213 <speciesReference species="M_4abut_c" stoichiometry="1.000000"/>
1214 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
1215 </listOfReactants>
1216 <listOfProducts>
1217 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
1218 <speciesReference species="M_sucsal_c" stoichiometry="1.000000"/>
1219 </listOfProducts>
1220 </reaction>
1221 <reaction id="R_ABUTD" name="R_Aminobutyraldehyde_dehydrogenase" reversible="false">
1222 <notes>
1223 <html:p>GENE_ASSOCIATION: </html:p>
1224 <html:p>PROTEIN_ASSOCIATION: </html:p>
1225 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
1226 <html:p>PROTEIN_CLASS: 1.2.1.19</html:p>
1227 </notes>
1228 <listOfReactants>
1229 <speciesReference species="M_4abutn_c" stoichiometry="1.000000"/>
1230 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
1231 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
1232 </listOfReactants>
1233 <listOfProducts>
1234 <speciesReference species="M_4abut_c" stoichiometry="1.000000"/>
1235 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
1236 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
1237 </listOfProducts>
1238 </reaction>
1239 <reaction id="R_ABUTt2" name="R_4_aminobutyrate_transport_in_via_proton_symport" reversible="false">
1240 <notes>
1241 <html:p>GENE_ASSOCIATION: b2663</html:p>
1242 <html:p>PROTEIN_ASSOCIATION: GabP</html:p>
1243 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
1244 <html:p>PROTEIN_CLASS: </html:p>
1245 </notes>
1246 <listOfReactants>
1247 <speciesReference species="M_4abut_e" stoichiometry="1.000000"/>
1248 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
1249 </listOfReactants>
1250 <listOfProducts>
1251 <speciesReference species="M_4abut_c" stoichiometry="1.000000"/>
1252 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1253 </listOfProducts>
1254 </reaction>
1255 <reaction id="R_ACACCT" name="R_acetyl_CoAacetoacetyl_CoA_transferase" reversible="false">
1256 <notes>
1257 <html:p>GENE_ASSOCIATION: ( b2221 and b2222 )</html:p>
1258 <html:p>PROTEIN_ASSOCIATION: AtoADec</html:p>
1259 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
1260 <html:p>PROTEIN_CLASS: </html:p>
1261 </notes>
1262 <listOfReactants>
1263 <speciesReference species="M_acac_c" stoichiometry="1.000000"/>
1264 <speciesReference species="M_accoa_c" stoichiometry="1.000000"/>
1265 </listOfReactants>
1266 <listOfProducts>
1267 <speciesReference species="M_aacoa_c" stoichiometry="1.000000"/>
1268 <speciesReference species="M_ac_c" stoichiometry="1.000000"/>
1269 </listOfProducts>
1270 </reaction>
1271 <reaction id="R_ACACT1r" name="R_acetyl_CoA_C_acetyltransferase" reversible="true">
1272 <notes>
1273 <html:p>GENE_ASSOCIATION: b2224</html:p>
1274 <html:p>PROTEIN_ASSOCIATION: AtoBec</html:p>
1275 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
1276 <html:p>PROTEIN_CLASS: 2.3.1.9</html:p>
1277 </notes>
1278 <listOfReactants>
1279 <speciesReference species="M_accoa_c" stoichiometry="2.000000"/>
1280 </listOfReactants>
1281 <listOfProducts>
1282 <speciesReference species="M_aacoa_c" stoichiometry="1.000000"/>
1283 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
1284 </listOfProducts>
1285 </reaction>
1286 <reaction id="R_ACACt2" name="R_acetoacetate_transport_via_proton_symport" reversible="true">
1287 <notes>
1288 <html:p>GENE_ASSOCIATION: b2223</html:p>
1289 <html:p>PROTEIN_ASSOCIATION: AtoE</html:p>
1290 <html:p>SUBSYSTEM: S_Putative_Transporters</html:p>
1291 <html:p>PROTEIN_CLASS: </html:p>
1292 </notes>
1293 <listOfReactants>
1294 <speciesReference species="M_acac_e" stoichiometry="1.000000"/>
1295 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
1296 </listOfReactants>
1297 <listOfProducts>
1298 <speciesReference species="M_acac_c" stoichiometry="1.000000"/>
1299 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1300 </listOfProducts>
1301 </reaction>
1302 <reaction id="R_ACALDi" name="R_acetaldehyde_dehydrogenase__acetylating_" reversible="false">
1303 <notes>
1304 <html:p>GENE_ASSOCIATION: b0351</html:p>
1305 <html:p>PROTEIN_ASSOCIATION: MhpF</html:p>
1306 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
1307 <html:p>PROTEIN_CLASS: 1.2.1.10</html:p>
1308 </notes>
1309 <listOfReactants>
1310 <speciesReference species="M_acald_c" stoichiometry="1.000000"/>
1311 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
1312 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
1313 </listOfReactants>
1314 <listOfProducts>
1315 <speciesReference species="M_accoa_c" stoichiometry="1.000000"/>
1316 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1317 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
1318 </listOfProducts>
1319 </reaction>
1320 <reaction id="R_ACALDt" name="R_acetaldehyde_reversible_transport" reversible="true">
1321 <notes>
1322 <html:p>GENE_ASSOCIATION: </html:p>
1323 <html:p>PROTEIN_ASSOCIATION: </html:p>
1324 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
1325 <html:p>PROTEIN_CLASS: </html:p>
1326 </notes>
1327 <listOfReactants>
1328 <speciesReference species="M_acald_e" stoichiometry="1.000000"/>
1329 </listOfReactants>
1330 <listOfProducts>
1331 <speciesReference species="M_acald_c" stoichiometry="1.000000"/>
1332 </listOfProducts>
1333 </reaction>
1334 <reaction id="R_ACBIPGT" name="R_Adenosyl_cobinamide_phosphate_guanyltransferase" reversible="false">
1335 <notes>
1336 <html:p>GENE_ASSOCIATION: b1993</html:p>
1337 <html:p>PROTEIN_ASSOCIATION: CobU</html:p>
1338 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
1339 <html:p>PROTEIN_CLASS: </html:p>
1340 </notes>
1341 <listOfReactants>
1342 <speciesReference species="M_adocbip_c" stoichiometry="1.000000"/>
1343 <speciesReference species="M_gtp_c" stoichiometry="1.000000"/>
1344 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1345 </listOfReactants>
1346 <listOfProducts>
1347 <speciesReference species="M_agdpcbi_c" stoichiometry="1.000000"/>
1348 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
1349 </listOfProducts>
1350 </reaction>
1351 <reaction id="R_ACCOACr" name="R_acetyl_CoA_carboxylase__reversible_reaction" reversible="true">
1352 <notes>
1353 <html:p>GENE_ASSOCIATION: ( b0185 and b2316 and b3255 and b3256 )</html:p>
1354 <html:p>PROTEIN_ASSOCIATION: Acc</html:p>
1355 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
1356 <html:p>PROTEIN_CLASS: 6.4.1.2</html:p>
1357 </notes>
1358 <listOfReactants>
1359 <speciesReference species="M_accoa_c" stoichiometry="1.000000"/>
1360 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
1361 <speciesReference species="M_hco3_c" stoichiometry="1.000000"/>
1362 </listOfReactants>
1363 <listOfProducts>
1364 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
1365 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1366 <speciesReference species="M_malcoa_c" stoichiometry="1.000000"/>
1367 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
1368 </listOfProducts>
1369 </reaction>
1370 <reaction id="R_ACCOAL" name="R_acetate_CoA_ligase__ADP_forming_" reversible="false">
1371 <notes>
1372 <html:p>GENE_ASSOCIATION: b0335</html:p>
1373 <html:p>PROTEIN_ASSOCIATION: PrpE</html:p>
1374 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
1375 <html:p>PROTEIN_CLASS: 6.2.1.13</html:p>
1376 </notes>
1377 <listOfReactants>
1378 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
1379 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
1380 <speciesReference species="M_ppa_c" stoichiometry="1.000000"/>
1381 </listOfReactants>
1382 <listOfProducts>
1383 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
1384 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
1385 <speciesReference species="M_ppcoa_c" stoichiometry="1.000000"/>
1386 </listOfProducts>
1387 </reaction>
1388 <reaction id="R_ACGAMT" name="R_UDP_N_acetylglucosamineundecaprenylphosphate_N_acetylglucosamine__1_phosphate_transferase" reversible="false">
1389 <notes>
1390 <html:p>GENE_ASSOCIATION: b3784</html:p>
1391 <html:p>PROTEIN_ASSOCIATION: WecA</html:p>
1392 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
1393 <html:p>PROTEIN_CLASS: </html:p>
1394 </notes>
1395 <listOfReactants>
1396 <speciesReference species="M_uacgam_c" stoichiometry="1.000000"/>
1397 <speciesReference species="M_udcpp_c" stoichiometry="1.000000"/>
1398 </listOfReactants>
1399 <listOfProducts>
1400 <speciesReference species="M_ump_c" stoichiometry="1.000000"/>
1401 <speciesReference species="M_unaga_c" stoichiometry="1.000000"/>
1402 </listOfProducts>
1403 </reaction>
1404 <reaction id="R_ACGApts" name="R_N_Acetyl_D_glucosamine_transport_via_PEPPyr_PTS" reversible="false">
1405 <notes>
1406 <html:p>GENE_ASSOCIATION: ( ( b0679 and b2415 and b2416 ) or ( b2417 and b1101 and b2415 and b2416 ) )</html:p>
1407 <html:p>PROTEIN_ASSOCIATION: ( NagE and PtsH and PtsI ) or ( Crr and PtsG and PtsH and PtsI )</html:p>
1408 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
1409 <html:p>PROTEIN_CLASS: </html:p>
1410 </notes>
1411 <listOfReactants>
1412 <speciesReference species="M_pep_c" stoichiometry="1.000000"/>
1413 <speciesReference species="M_acgam_e" stoichiometry="1.000000"/>
1414 </listOfReactants>
1415 <listOfProducts>
1416 <speciesReference species="M_acgam6p_c" stoichiometry="1.000000"/>
1417 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
1418 </listOfProducts>
1419 </reaction>
1420 <reaction id="R_ACGK" name="R_acetylglutamate_kinase" reversible="false">
1421 <notes>
1422 <html:p>GENE_ASSOCIATION: b3959</html:p>
1423 <html:p>PROTEIN_ASSOCIATION: ArgB</html:p>
1424 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
1425 <html:p>PROTEIN_CLASS: 2.7.2.8</html:p>
1426 </notes>
1427 <listOfReactants>
1428 <speciesReference species="M_acglu_c" stoichiometry="1.000000"/>
1429 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
1430 </listOfReactants>
1431 <listOfProducts>
1432 <speciesReference species="M_acg5p_c" stoichiometry="1.000000"/>
1433 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
1434 </listOfProducts>
1435 </reaction>
1436 <reaction id="R_ACGS" name="R_N_acetylglutamate_synthase" reversible="false">
1437 <notes>
1438 <html:p>GENE_ASSOCIATION: b2818</html:p>
1439 <html:p>PROTEIN_ASSOCIATION: ArgA</html:p>
1440 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
1441 <html:p>PROTEIN_CLASS: 2.3.1.1</html:p>
1442 </notes>
1443 <listOfReactants>
1444 <speciesReference species="M_accoa_c" stoichiometry="1.000000"/>
1445 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
1446 </listOfReactants>
1447 <listOfProducts>
1448 <speciesReference species="M_acglu_c" stoichiometry="1.000000"/>
1449 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
1450 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1451 </listOfProducts>
1452 </reaction>
1453 <reaction id="R_ACHBS" name="R_2_aceto_2_hydroxybutanoate_synthase" reversible="false">
1454 <notes>
1455 <html:p>GENE_ASSOCIATION: ( ( b3670 and b3671 ) or ( b3767 and b3768 and b3769 ) or ( b0077 and b0078 ) )</html:p>
1456 <html:p>PROTEIN_ASSOCIATION: ( IlvB ) or ( IlvG ) or ( IlvH )</html:p>
1457 <html:p>SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism</html:p>
1458 <html:p>PROTEIN_CLASS: </html:p>
1459 </notes>
1460 <listOfReactants>
1461 <speciesReference species="M_2obut_c" stoichiometry="1.000000"/>
1462 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1463 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
1464 </listOfReactants>
1465 <listOfProducts>
1466 <speciesReference species="M_2ahbut_c" stoichiometry="1.000000"/>
1467 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
1468 </listOfProducts>
1469 </reaction>
1470 <reaction id="R_ACKr" name="R_acetate_kinase" reversible="true">
1471 <notes>
1472 <html:p>GENE_ASSOCIATION: ( b2296 or b1849 or b3115 )</html:p>
1473 <html:p>PROTEIN_ASSOCIATION: ( AckA ) or ( PurT ) or ( TdcD )</html:p>
1474 <html:p>SUBSYSTEM: S_Pyruvate_Metabolism</html:p>
1475 <html:p>PROTEIN_CLASS: 2.7.2.1</html:p>
1476 </notes>
1477 <listOfReactants>
1478 <speciesReference species="M_ac_c" stoichiometry="1.000000"/>
1479 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
1480 </listOfReactants>
1481 <listOfProducts>
1482 <speciesReference species="M_actp_c" stoichiometry="1.000000"/>
1483 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
1484 </listOfProducts>
1485 </reaction>
1486 <reaction id="R_ACLS" name="R_acetolactate_synthase" reversible="false">
1487 <notes>
1488 <html:p>GENE_ASSOCIATION: ( ( b3670 and b3671 ) or ( b3767 and b3768 and b3769 ) or ( b0077 and b0078 ) )</html:p>
1489 <html:p>PROTEIN_ASSOCIATION: ( IlvB ) or ( IlvG ) or ( IlvH )</html:p>
1490 <html:p>SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism</html:p>
1491 <html:p>PROTEIN_CLASS: 4.1.3.18</html:p>
1492 </notes>
1493 <listOfReactants>
1494 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1495 <speciesReference species="M_pyr_c" stoichiometry="2.000000"/>
1496 </listOfReactants>
1497 <listOfProducts>
1498 <speciesReference species="M_alac_S_c" stoichiometry="1.000000"/>
1499 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
1500 </listOfProducts>
1501 </reaction>
1502 <reaction id="R_ACMAMUT" name="R_UDP_N_acetyl_D_mannosaminuronic_acid_transferase" reversible="false">
1503 <notes>
1504 <html:p>GENE_ASSOCIATION: b3794</html:p>
1505 <html:p>PROTEIN_ASSOCIATION: WecG</html:p>
1506 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
1507 <html:p>PROTEIN_CLASS: </html:p>
1508 </notes>
1509 <listOfReactants>
1510 <speciesReference species="M_uacmamu_c" stoichiometry="1.000000"/>
1511 <speciesReference species="M_unaga_c" stoichiometry="1.000000"/>
1512 </listOfReactants>
1513 <listOfProducts>
1514 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1515 <speciesReference species="M_udp_c" stoichiometry="1.000000"/>
1516 <speciesReference species="M_unagamu_c" stoichiometry="1.000000"/>
1517 </listOfProducts>
1518 </reaction>
1519 <reaction id="R_ACMANApts" name="R_N_acetyl_D_mannosamine_transport_via_PTS" reversible="false">
1520 <notes>
1521 <html:p>GENE_ASSOCIATION: ( b1817 and b1818 and b1819 and b2415 and b2416 )</html:p>
1522 <html:p>PROTEIN_ASSOCIATION: ( ManX and ManY and ManZ and PtsH and PtsI )</html:p>
1523 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
1524 <html:p>PROTEIN_CLASS: </html:p>
1525 </notes>
1526 <listOfReactants>
1527 <speciesReference species="M_pep_c" stoichiometry="1.000000"/>
1528 <speciesReference species="M_acmana_e" stoichiometry="1.000000"/>
1529 </listOfReactants>
1530 <listOfProducts>
1531 <speciesReference species="M_acmanap_c" stoichiometry="1.000000"/>
1532 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
1533 </listOfProducts>
1534 </reaction>
1535 <reaction id="R_ACNAMt2" name="R_N_acetylneuraminate_proton_symport" reversible="false">
1536 <notes>
1537 <html:p>GENE_ASSOCIATION: b3224</html:p>
1538 <html:p>PROTEIN_ASSOCIATION: NanT</html:p>
1539 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
1540 <html:p>PROTEIN_CLASS: </html:p>
1541 </notes>
1542 <listOfReactants>
1543 <speciesReference species="M_acnam_e" stoichiometry="1.000000"/>
1544 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
1545 </listOfReactants>
1546 <listOfProducts>
1547 <speciesReference species="M_acnam_c" stoichiometry="1.000000"/>
1548 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1549 </listOfProducts>
1550 </reaction>
1551 <reaction id="R_ACNML" name="R_N_Acetylneuraminate_lyase" reversible="false">
1552 <notes>
1553 <html:p>GENE_ASSOCIATION: b3225</html:p>
1554 <html:p>PROTEIN_ASSOCIATION: NanA</html:p>
1555 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
1556 <html:p>PROTEIN_CLASS: 4.1.3.3</html:p>
1557 </notes>
1558 <listOfReactants>
1559 <speciesReference species="M_acnam_c" stoichiometry="1.000000"/>
1560 </listOfReactants>
1561 <listOfProducts>
1562 <speciesReference species="M_acmana_c" stoichiometry="1.000000"/>
1563 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
1564 </listOfProducts>
1565 </reaction>
1566 <reaction id="R_ACOATA" name="R_Acetyl_CoA_ACP_transacylase" reversible="true">
1567 <notes>
1568 <html:p>GENE_ASSOCIATION: b1091</html:p>
1569 <html:p>PROTEIN_ASSOCIATION: FabHec</html:p>
1570 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
1571 <html:p>PROTEIN_CLASS: 2.3.1.38</html:p>
1572 </notes>
1573 <listOfReactants>
1574 <speciesReference species="M_ACP_c" stoichiometry="1.000000"/>
1575 <speciesReference species="M_accoa_c" stoichiometry="1.000000"/>
1576 </listOfReactants>
1577 <listOfProducts>
1578 <speciesReference species="M_acACP_c" stoichiometry="1.000000"/>
1579 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
1580 </listOfProducts>
1581 </reaction>
1582 <reaction id="R_ACODA" name="R_acetylornithine_deacetylase" reversible="false">
1583 <notes>
1584 <html:p>GENE_ASSOCIATION: b3957</html:p>
1585 <html:p>PROTEIN_ASSOCIATION: ArgE</html:p>
1586 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
1587 <html:p>PROTEIN_CLASS: 3.5.1.16</html:p>
1588 </notes>
1589 <listOfReactants>
1590 <speciesReference species="M_acorn_c" stoichiometry="1.000000"/>
1591 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
1592 </listOfReactants>
1593 <listOfProducts>
1594 <speciesReference species="M_ac_c" stoichiometry="1.000000"/>
1595 <speciesReference species="M_orn_c" stoichiometry="1.000000"/>
1596 </listOfProducts>
1597 </reaction>
1598 <reaction id="R_ACONMT" name="R_Trans_aconitate_methyltransferase" reversible="false">
1599 <notes>
1600 <html:p>GENE_ASSOCIATION: b1519</html:p>
1601 <html:p>PROTEIN_ASSOCIATION: Tam</html:p>
1602 <html:p>SUBSYSTEM: S_Unassigned</html:p>
1603 <html:p>PROTEIN_CLASS: </html:p>
1604 </notes>
1605 <listOfReactants>
1606 <speciesReference species="M_acon_T_c" stoichiometry="1.000000"/>
1607 <speciesReference species="M_amet_c" stoichiometry="1.000000"/>
1608 </listOfReactants>
1609 <listOfProducts>
1610 <speciesReference species="M_aconm_c" stoichiometry="1.000000"/>
1611 <speciesReference species="M_ahcys_c" stoichiometry="1.000000"/>
1612 </listOfProducts>
1613 </reaction>
1614 <reaction id="R_ACONT" name="R_aconitase" reversible="true">
1615 <notes>
1616 <html:p>GENE_ASSOCIATION: ( b1276 or b0118 )</html:p>
1617 <html:p>PROTEIN_ASSOCIATION: ( AcnA ) or ( AcnB )</html:p>
1618 <html:p>SUBSYSTEM: S_Citric_Acid_Cycle</html:p>
1619 <html:p>PROTEIN_CLASS: 4.2.1.3</html:p>
1620 </notes>
1621 <listOfReactants>
1622 <speciesReference species="M_cit_c" stoichiometry="1.000000"/>
1623 </listOfReactants>
1624 <listOfProducts>
1625 <speciesReference species="M_icit_c" stoichiometry="1.000000"/>
1626 </listOfProducts>
1627 </reaction>
1628 <reaction id="R_ACOTA" name="R_acetylornithine_transaminase" reversible="true">
1629 <notes>
1630 <html:p>GENE_ASSOCIATION: b3359</html:p>
1631 <html:p>PROTEIN_ASSOCIATION: ArgD</html:p>
1632 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
1633 <html:p>PROTEIN_CLASS: 2.6.1.11</html:p>
1634 </notes>
1635 <listOfReactants>
1636 <speciesReference species="M_acorn_c" stoichiometry="1.000000"/>
1637 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
1638 </listOfReactants>
1639 <listOfProducts>
1640 <speciesReference species="M_acg5sa_c" stoichiometry="1.000000"/>
1641 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
1642 </listOfProducts>
1643 </reaction>
1644 <reaction id="R_ACPS1" name="R_acyl_carrier_protein_synthase" reversible="false">
1645 <notes>
1646 <html:p>GENE_ASSOCIATION: b2563</html:p>
1647 <html:p>PROTEIN_ASSOCIATION: AcpS</html:p>
1648 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
1649 <html:p>PROTEIN_CLASS: 2.7.8.7</html:p>
1650 </notes>
1651 <listOfReactants>
1652 <speciesReference species="M_apoACP_c" stoichiometry="1.000000"/>
1653 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
1654 </listOfReactants>
1655 <listOfProducts>
1656 <speciesReference species="M_ACP_c" stoichiometry="1.000000"/>
1657 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1658 <speciesReference species="M_pap_c" stoichiometry="1.000000"/>
1659 </listOfProducts>
1660 </reaction>
1661 <reaction id="R_ACS" name="R_acetyl_CoA_synthetase" reversible="false">
1662 <notes>
1663 <html:p>GENE_ASSOCIATION: b4069</html:p>
1664 <html:p>PROTEIN_ASSOCIATION: Acs</html:p>
1665 <html:p>SUBSYSTEM: S_Pyruvate_Metabolism</html:p>
1666 <html:p>PROTEIN_CLASS: 6.2.1.1</html:p>
1667 </notes>
1668 <listOfReactants>
1669 <speciesReference species="M_ac_c" stoichiometry="1.000000"/>
1670 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
1671 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
1672 </listOfReactants>
1673 <listOfProducts>
1674 <speciesReference species="M_accoa_c" stoichiometry="1.000000"/>
1675 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
1676 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
1677 </listOfProducts>
1678 </reaction>
1679 <reaction id="R_ACt2r" name="R_acetate_reversible_transport_via_proton_symport" reversible="true">
1680 <notes>
1681 <html:p>GENE_ASSOCIATION: </html:p>
1682 <html:p>PROTEIN_ASSOCIATION: </html:p>
1683 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
1684 <html:p>PROTEIN_CLASS: </html:p>
1685 </notes>
1686 <listOfReactants>
1687 <speciesReference species="M_ac_e" stoichiometry="1.000000"/>
1688 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
1689 </listOfReactants>
1690 <listOfProducts>
1691 <speciesReference species="M_ac_c" stoichiometry="1.000000"/>
1692 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1693 </listOfProducts>
1694 </reaction>
1695 <reaction id="R_ADA" name="R_Adenosine_deaminase" reversible="false">
1696 <notes>
1697 <html:p>GENE_ASSOCIATION: b1623</html:p>
1698 <html:p>PROTEIN_ASSOCIATION: Add</html:p>
1699 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
1700 <html:p>PROTEIN_CLASS: 3.5.4.4</html:p>
1701 </notes>
1702 <listOfReactants>
1703 <speciesReference species="M_adn_c" stoichiometry="1.000000"/>
1704 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1705 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
1706 </listOfReactants>
1707 <listOfProducts>
1708 <speciesReference species="M_ins_c" stoichiometry="1.000000"/>
1709 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
1710 </listOfProducts>
1711 </reaction>
1712 <reaction id="R_ADCL" name="R_4_aminobenzoate_synthase" reversible="false">
1713 <notes>
1714 <html:p>GENE_ASSOCIATION: b1096</html:p>
1715 <html:p>PROTEIN_ASSOCIATION: PabC</html:p>
1716 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
1717 <html:p>PROTEIN_CLASS: </html:p>
1718 </notes>
1719 <listOfReactants>
1720 <speciesReference species="M_4adcho_c" stoichiometry="1.000000"/>
1721 </listOfReactants>
1722 <listOfProducts>
1723 <speciesReference species="M_4abz_c" stoichiometry="1.000000"/>
1724 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1725 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
1726 </listOfProducts>
1727 </reaction>
1728 <reaction id="R_ADCS" name="R_4_amino_4_deoxychorismate_synthase" reversible="false">
1729 <notes>
1730 <html:p>GENE_ASSOCIATION: ( b3360 and b1812 )</html:p>
1731 <html:p>PROTEIN_ASSOCIATION: ( PabA and PabBec )</html:p>
1732 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
1733 <html:p>PROTEIN_CLASS: </html:p>
1734 </notes>
1735 <listOfReactants>
1736 <speciesReference species="M_chor_c" stoichiometry="1.000000"/>
1737 <speciesReference species="M_gln_L_c" stoichiometry="1.000000"/>
1738 </listOfReactants>
1739 <listOfProducts>
1740 <speciesReference species="M_4adcho_c" stoichiometry="1.000000"/>
1741 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
1742 </listOfProducts>
1743 </reaction>
1744 <reaction id="R_ADD" name="R_adenine_deaminase" reversible="false">
1745 <notes>
1746 <html:p>GENE_ASSOCIATION: b3665</html:p>
1747 <html:p>PROTEIN_ASSOCIATION: YicP</html:p>
1748 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
1749 <html:p>PROTEIN_CLASS: 3.5.4.2</html:p>
1750 </notes>
1751 <listOfReactants>
1752 <speciesReference species="M_ade_c" stoichiometry="1.000000"/>
1753 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1754 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
1755 </listOfReactants>
1756 <listOfProducts>
1757 <speciesReference species="M_hxan_c" stoichiometry="1.000000"/>
1758 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
1759 </listOfProducts>
1760 </reaction>
1761 <reaction id="R_ADEt2r" name="R_adenine_transport_via_proton_symport__reversible_" reversible="true">
1762 <notes>
1763 <html:p>GENE_ASSOCIATION: b3654</html:p>
1764 <html:p>PROTEIN_ASSOCIATION: YicE</html:p>
1765 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
1766 <html:p>PROTEIN_CLASS: </html:p>
1767 </notes>
1768 <listOfReactants>
1769 <speciesReference species="M_ade_e" stoichiometry="1.000000"/>
1770 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
1771 </listOfReactants>
1772 <listOfProducts>
1773 <speciesReference species="M_ade_c" stoichiometry="1.000000"/>
1774 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1775 </listOfProducts>
1776 </reaction>
1777 <reaction id="R_ADHEr" name="R_Acetaldehyde_dehydrogenase" reversible="true">
1778 <notes>
1779 <html:p>GENE_ASSOCIATION: b1241</html:p>
1780 <html:p>PROTEIN_ASSOCIATION: AdhE</html:p>
1781 <html:p>SUBSYSTEM: S_Pyruvate_Metabolism</html:p>
1782 <html:p>PROTEIN_CLASS: </html:p>
1783 </notes>
1784 <listOfReactants>
1785 <speciesReference species="M_accoa_c" stoichiometry="1.000000"/>
1786 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
1787 <speciesReference species="M_nadh_c" stoichiometry="2.000000"/>
1788 </listOfReactants>
1789 <listOfProducts>
1790 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
1791 <speciesReference species="M_etoh_c" stoichiometry="1.000000"/>
1792 <speciesReference species="M_nad_c" stoichiometry="2.000000"/>
1793 </listOfProducts>
1794 </reaction>
1795 <reaction id="R_ADK1" name="R_adenylate_kinase" reversible="true">
1796 <notes>
1797 <html:p>GENE_ASSOCIATION: b0474</html:p>
1798 <html:p>PROTEIN_ASSOCIATION: Adk</html:p>
1799 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
1800 <html:p>PROTEIN_CLASS: 2.7.4.3</html:p>
1801 </notes>
1802 <listOfReactants>
1803 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
1804 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
1805 </listOfReactants>
1806 <listOfProducts>
1807 <speciesReference species="M_adp_c" stoichiometry="2.000000"/>
1808 </listOfProducts>
1809 </reaction>
1810 <reaction id="R_ADK3" name="R_adentylate_kinase__GTP_" reversible="true">
1811 <notes>
1812 <html:p>GENE_ASSOCIATION: b0474</html:p>
1813 <html:p>PROTEIN_ASSOCIATION: Adk</html:p>
1814 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
1815 <html:p>PROTEIN_CLASS: </html:p>
1816 </notes>
1817 <listOfReactants>
1818 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
1819 <speciesReference species="M_gtp_c" stoichiometry="1.000000"/>
1820 </listOfReactants>
1821 <listOfProducts>
1822 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
1823 <speciesReference species="M_gdp_c" stoichiometry="1.000000"/>
1824 </listOfProducts>
1825 </reaction>
1826 <reaction id="R_ADK4" name="R_adentylate_kinase__ITP_" reversible="true">
1827 <notes>
1828 <html:p>GENE_ASSOCIATION: b0474</html:p>
1829 <html:p>PROTEIN_ASSOCIATION: Adk</html:p>
1830 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
1831 <html:p>PROTEIN_CLASS: </html:p>
1832 </notes>
1833 <listOfReactants>
1834 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
1835 <speciesReference species="M_itp_c" stoichiometry="1.000000"/>
1836 </listOfReactants>
1837 <listOfProducts>
1838 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
1839 <speciesReference species="M_idp_c" stoichiometry="1.000000"/>
1840 </listOfProducts>
1841 </reaction>
1842 <reaction id="R_ADMDCr" name="R_Adenosylmethionine_decarboxylase" reversible="true">
1843 <notes>
1844 <html:p>GENE_ASSOCIATION: b0120</html:p>
1845 <html:p>PROTEIN_ASSOCIATION: SpeD</html:p>
1846 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
1847 <html:p>PROTEIN_CLASS: 4.1.1.50</html:p>
1848 </notes>
1849 <listOfReactants>
1850 <speciesReference species="M_amet_c" stoichiometry="1.000000"/>
1851 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1852 </listOfReactants>
1853 <listOfProducts>
1854 <speciesReference species="M_ametam_c" stoichiometry="1.000000"/>
1855 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
1856 </listOfProducts>
1857 </reaction>
1858 <reaction id="R_ADNCYC" name="R_adenylate_cyclase" reversible="false">
1859 <notes>
1860 <html:p>GENE_ASSOCIATION: b3806</html:p>
1861 <html:p>PROTEIN_ASSOCIATION: CyaA</html:p>
1862 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
1863 <html:p>PROTEIN_CLASS: 4.6.1.1</html:p>
1864 </notes>
1865 <listOfReactants>
1866 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
1867 </listOfReactants>
1868 <listOfProducts>
1869 <speciesReference species="M_camp_c" stoichiometry="1.000000"/>
1870 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
1871 </listOfProducts>
1872 </reaction>
1873 <reaction id="R_ADNK1" name="R_adenosine_kinase" reversible="false">
1874 <notes>
1875 <html:p>GENE_ASSOCIATION: b0474</html:p>
1876 <html:p>PROTEIN_ASSOCIATION: Adk</html:p>
1877 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
1878 <html:p>PROTEIN_CLASS: 2.7.1.20</html:p>
1879 </notes>
1880 <listOfReactants>
1881 <speciesReference species="M_adn_c" stoichiometry="1.000000"/>
1882 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
1883 </listOfReactants>
1884 <listOfProducts>
1885 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
1886 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
1887 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1888 </listOfProducts>
1889 </reaction>
1890 <reaction id="R_ADNt2" name="R_adenosine_transport_in_via_proton_symport" reversible="false">
1891 <notes>
1892 <html:p>GENE_ASSOCIATION: ( b2964 or b2393 )</html:p>
1893 <html:p>PROTEIN_ASSOCIATION: ( NupG ) or ( NupCec )</html:p>
1894 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
1895 <html:p>PROTEIN_CLASS: </html:p>
1896 </notes>
1897 <listOfReactants>
1898 <speciesReference species="M_adn_e" stoichiometry="1.000000"/>
1899 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
1900 </listOfReactants>
1901 <listOfProducts>
1902 <speciesReference species="M_adn_c" stoichiometry="1.000000"/>
1903 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1904 </listOfProducts>
1905 </reaction>
1906 <reaction id="R_ADNt2r" name="R_adenosine_transport_in_via_proton_symport__reversible" reversible="true">
1907 <notes>
1908 <html:p>GENE_ASSOCIATION: b2406</html:p>
1909 <html:p>PROTEIN_ASSOCIATION: XapB</html:p>
1910 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
1911 <html:p>PROTEIN_CLASS: </html:p>
1912 </notes>
1913 <listOfReactants>
1914 <speciesReference species="M_adn_e" stoichiometry="1.000000"/>
1915 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
1916 </listOfReactants>
1917 <listOfProducts>
1918 <speciesReference species="M_adn_c" stoichiometry="1.000000"/>
1919 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1920 </listOfProducts>
1921 </reaction>
1922 <reaction id="R_ADOCBIK" name="R_Adenosyl_cobinamide_kinase" reversible="false">
1923 <notes>
1924 <html:p>GENE_ASSOCIATION: b1993</html:p>
1925 <html:p>PROTEIN_ASSOCIATION: CobU</html:p>
1926 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
1927 <html:p>PROTEIN_CLASS: </html:p>
1928 </notes>
1929 <listOfReactants>
1930 <speciesReference species="M_adocbi_c" stoichiometry="1.000000"/>
1931 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
1932 </listOfReactants>
1933 <listOfProducts>
1934 <speciesReference species="M_adocbip_c" stoichiometry="1.000000"/>
1935 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
1936 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1937 </listOfProducts>
1938 </reaction>
1939 <reaction id="R_ADOCBLS" name="R_Adenosylcobalamin_5__phosphate_synthase" reversible="false">
1940 <notes>
1941 <html:p>GENE_ASSOCIATION: b1992</html:p>
1942 <html:p>PROTEIN_ASSOCIATION: CobS</html:p>
1943 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
1944 <html:p>PROTEIN_CLASS: </html:p>
1945 </notes>
1946 <listOfReactants>
1947 <speciesReference species="M_agdpcbi_c" stoichiometry="1.000000"/>
1948 <speciesReference species="M_rdmbzi_c" stoichiometry="1.000000"/>
1949 </listOfReactants>
1950 <listOfProducts>
1951 <speciesReference species="M_adocbl_c" stoichiometry="1.000000"/>
1952 <speciesReference species="M_gmp_c" stoichiometry="1.000000"/>
1953 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1954 </listOfProducts>
1955 </reaction>
1956 <reaction id="R_ADPT" name="R_adenine_phosphoribosyltransferase" reversible="false">
1957 <notes>
1958 <html:p>GENE_ASSOCIATION: b0469</html:p>
1959 <html:p>PROTEIN_ASSOCIATION: Apt</html:p>
1960 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
1961 <html:p>PROTEIN_CLASS: 2.4.2.7</html:p>
1962 </notes>
1963 <listOfReactants>
1964 <speciesReference species="M_ade_c" stoichiometry="1.000000"/>
1965 <speciesReference species="M_prpp_c" stoichiometry="1.000000"/>
1966 </listOfReactants>
1967 <listOfProducts>
1968 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
1969 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
1970 </listOfProducts>
1971 </reaction>
1972 <reaction id="R_ADSK" name="R_adenylyl_sulfate_kinase" reversible="false">
1973 <notes>
1974 <html:p>GENE_ASSOCIATION: b2750</html:p>
1975 <html:p>PROTEIN_ASSOCIATION: CysC</html:p>
1976 <html:p>SUBSYSTEM: S_Cysteine_Metabolism</html:p>
1977 <html:p>PROTEIN_CLASS: 2.7.1.25</html:p>
1978 </notes>
1979 <listOfReactants>
1980 <speciesReference species="M_aps_c" stoichiometry="1.000000"/>
1981 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
1982 </listOfReactants>
1983 <listOfProducts>
1984 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
1985 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
1986 <speciesReference species="M_paps_c" stoichiometry="1.000000"/>
1987 </listOfProducts>
1988 </reaction>
1989 <reaction id="R_ADSL1r" name="R_adenylsuccinate_lyase" reversible="true">
1990 <notes>
1991 <html:p>GENE_ASSOCIATION: b1131</html:p>
1992 <html:p>PROTEIN_ASSOCIATION: PurB</html:p>
1993 <html:p>SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis</html:p>
1994 <html:p>PROTEIN_CLASS: 4.3.2.2</html:p>
1995 </notes>
1996 <listOfReactants>
1997 <speciesReference species="M_dcamp_c" stoichiometry="1.000000"/>
1998 </listOfReactants>
1999 <listOfProducts>
2000 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
2001 <speciesReference species="M_fum_c" stoichiometry="1.000000"/>
2002 </listOfProducts>
2003 </reaction>
2004 <reaction id="R_ADSL2r" name="R_adenylosuccinate_lyase" reversible="true">
2005 <notes>
2006 <html:p>GENE_ASSOCIATION: b1131</html:p>
2007 <html:p>PROTEIN_ASSOCIATION: PurB</html:p>
2008 <html:p>SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis</html:p>
2009 <html:p>PROTEIN_CLASS: 4.3.2.2</html:p>
2010 </notes>
2011 <listOfReactants>
2012 <speciesReference species="M_25aics_c" stoichiometry="1.000000"/>
2013 </listOfReactants>
2014 <listOfProducts>
2015 <speciesReference species="M_aicar_c" stoichiometry="1.000000"/>
2016 <speciesReference species="M_fum_c" stoichiometry="1.000000"/>
2017 </listOfProducts>
2018 </reaction>
2019 <reaction id="R_ADSS" name="R_adenylosuccinate_synthase" reversible="false">
2020 <notes>
2021 <html:p>GENE_ASSOCIATION: b4177</html:p>
2022 <html:p>PROTEIN_ASSOCIATION: PurA</html:p>
2023 <html:p>SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis</html:p>
2024 <html:p>PROTEIN_CLASS: 6.3.4.4</html:p>
2025 </notes>
2026 <listOfReactants>
2027 <speciesReference species="M_asp_L_c" stoichiometry="1.000000"/>
2028 <speciesReference species="M_gtp_c" stoichiometry="1.000000"/>
2029 <speciesReference species="M_imp_c" stoichiometry="1.000000"/>
2030 </listOfReactants>
2031 <listOfProducts>
2032 <speciesReference species="M_dcamp_c" stoichiometry="1.000000"/>
2033 <speciesReference species="M_gdp_c" stoichiometry="1.000000"/>
2034 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
2035 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
2036 </listOfProducts>
2037 </reaction>
2038 <reaction id="R_AGDC" name="R_N_acetylglucosamine_6_phosphate_deacetylase" reversible="false">
2039 <notes>
2040 <html:p>GENE_ASSOCIATION: b0677</html:p>
2041 <html:p>PROTEIN_ASSOCIATION: NagA</html:p>
2042 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
2043 <html:p>PROTEIN_CLASS: 3.5.1.25</html:p>
2044 </notes>
2045 <listOfReactants>
2046 <speciesReference species="M_acgam6p_c" stoichiometry="1.000000"/>
2047 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
2048 </listOfReactants>
2049 <listOfProducts>
2050 <speciesReference species="M_ac_c" stoichiometry="1.000000"/>
2051 <speciesReference species="M_gam6p_c" stoichiometry="1.000000"/>
2052 </listOfProducts>
2053 </reaction>
2054 <reaction id="R_AGMHE" name="R_ADP_D_glycero_D_manno_heptose_epimerase" reversible="false">
2055 <notes>
2056 <html:p>GENE_ASSOCIATION: b3619</html:p>
2057 <html:p>PROTEIN_ASSOCIATION: RfaD</html:p>
2058 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
2059 <html:p>PROTEIN_CLASS: 5.1.3.20</html:p>
2060 </notes>
2061 <listOfReactants>
2062 <speciesReference species="M_adphep_DD_c" stoichiometry="1.000000"/>
2063 </listOfReactants>
2064 <listOfProducts>
2065 <speciesReference species="M_adphep_LD_c" stoichiometry="1.000000"/>
2066 </listOfProducts>
2067 </reaction>
2068 <reaction id="R_AGMT" name="R_agmatinase" reversible="false">
2069 <notes>
2070 <html:p>GENE_ASSOCIATION: b2937</html:p>
2071 <html:p>PROTEIN_ASSOCIATION: SpeB</html:p>
2072 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
2073 <html:p>PROTEIN_CLASS: 3.5.3.11</html:p>
2074 </notes>
2075 <listOfReactants>
2076 <speciesReference species="M_agm_c" stoichiometry="1.000000"/>
2077 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
2078 </listOfReactants>
2079 <listOfProducts>
2080 <speciesReference species="M_ptrc_c" stoichiometry="1.000000"/>
2081 <speciesReference species="M_urea_c" stoichiometry="1.000000"/>
2082 </listOfProducts>
2083 </reaction>
2084 <reaction id="R_AGPR" name="R_N_acetyl_g_glutamyl_phosphate_reductase" reversible="true">
2085 <notes>
2086 <html:p>GENE_ASSOCIATION: b3958</html:p>
2087 <html:p>PROTEIN_ASSOCIATION: ArgC</html:p>
2088 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
2089 <html:p>PROTEIN_CLASS: 1.2.1.38</html:p>
2090 </notes>
2091 <listOfReactants>
2092 <speciesReference species="M_acg5sa_c" stoichiometry="1.000000"/>
2093 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
2094 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
2095 </listOfReactants>
2096 <listOfProducts>
2097 <speciesReference species="M_acg5p_c" stoichiometry="1.000000"/>
2098 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2099 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
2100 </listOfProducts>
2101 </reaction>
2102 <reaction id="R_AHC" name="R_adenosylhomocysteinase" reversible="true">
2103 <notes>
2104 <html:p>GENE_ASSOCIATION: </html:p>
2105 <html:p>PROTEIN_ASSOCIATION: </html:p>
2106 <html:p>SUBSYSTEM: S_Methionine_Metabolism</html:p>
2107 <html:p>PROTEIN_CLASS: 3.3.1.1</html:p>
2108 </notes>
2109 <listOfReactants>
2110 <speciesReference species="M_ahcys_c" stoichiometry="1.000000"/>
2111 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
2112 </listOfReactants>
2113 <listOfProducts>
2114 <speciesReference species="M_adn_c" stoichiometry="1.000000"/>
2115 <speciesReference species="M_hcys_L_c" stoichiometry="1.000000"/>
2116 </listOfProducts>
2117 </reaction>
2118 <reaction id="R_AHCYSNS" name="R_S_adenosylhomocysteine_nucleosidase" reversible="false">
2119 <notes>
2120 <html:p>GENE_ASSOCIATION: b0159</html:p>
2121 <html:p>PROTEIN_ASSOCIATION: Mtn</html:p>
2122 <html:p>SUBSYSTEM: S_Methionine_Metabolism</html:p>
2123 <html:p>PROTEIN_CLASS: 3.2.2.9</html:p>
2124 </notes>
2125 <listOfReactants>
2126 <speciesReference species="M_ahcys_c" stoichiometry="1.000000"/>
2127 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
2128 </listOfReactants>
2129 <listOfProducts>
2130 <speciesReference species="M_ade_c" stoichiometry="1.000000"/>
2131 <speciesReference species="M_rhcys_c" stoichiometry="1.000000"/>
2132 </listOfProducts>
2133 </reaction>
2134 <reaction id="R_AICART" name="R_phosphoribosylaminoimidazolecarboxamide_formyltransferase" reversible="true">
2135 <notes>
2136 <html:p>GENE_ASSOCIATION: b4006</html:p>
2137 <html:p>PROTEIN_ASSOCIATION: PurH</html:p>
2138 <html:p>SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis</html:p>
2139 <html:p>PROTEIN_CLASS: 2.1.2.3</html:p>
2140 </notes>
2141 <listOfReactants>
2142 <speciesReference species="M_10fthf_c" stoichiometry="1.000000"/>
2143 <speciesReference species="M_aicar_c" stoichiometry="1.000000"/>
2144 </listOfReactants>
2145 <listOfProducts>
2146 <speciesReference species="M_fprica_c" stoichiometry="1.000000"/>
2147 <speciesReference species="M_thf_c" stoichiometry="1.000000"/>
2148 </listOfProducts>
2149 </reaction>
2150 <reaction id="R_AIRC2" name="R_phosphoribosylaminoimidazole_carboxylase" reversible="false">
2151 <notes>
2152 <html:p>GENE_ASSOCIATION: b0522</html:p>
2153 <html:p>PROTEIN_ASSOCIATION: PurK</html:p>
2154 <html:p>SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis</html:p>
2155 <html:p>PROTEIN_CLASS: </html:p>
2156 </notes>
2157 <listOfReactants>
2158 <speciesReference species="M_air_c" stoichiometry="1.000000"/>
2159 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
2160 <speciesReference species="M_hco3_c" stoichiometry="1.000000"/>
2161 </listOfReactants>
2162 <listOfProducts>
2163 <speciesReference species="M_5caiz_c" stoichiometry="1.000000"/>
2164 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
2165 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2166 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
2167 </listOfProducts>
2168 </reaction>
2169 <reaction id="R_AIRC3" name="R_phosphoribosylaminoimidazole_carboxylase__mutase_rxn_" reversible="true">
2170 <notes>
2171 <html:p>GENE_ASSOCIATION: b0523</html:p>
2172 <html:p>PROTEIN_ASSOCIATION: PurE</html:p>
2173 <html:p>SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis</html:p>
2174 <html:p>PROTEIN_CLASS: </html:p>
2175 </notes>
2176 <listOfReactants>
2177 <speciesReference species="M_5aizc_c" stoichiometry="1.000000"/>
2178 </listOfReactants>
2179 <listOfProducts>
2180 <speciesReference species="M_5caiz_c" stoichiometry="1.000000"/>
2181 </listOfProducts>
2182 </reaction>
2183 <reaction id="R_AKGDH" name="R_2_Oxogluterate_dehydrogenase" reversible="false">
2184 <notes>
2185 <html:p>GENE_ASSOCIATION: ( b0116 and b0726 and b0727 )</html:p>
2186 <html:p>PROTEIN_ASSOCIATION: ( LpdA and SucAec and SucBec )</html:p>
2187 <html:p>SUBSYSTEM: S_Citric_Acid_Cycle</html:p>
2188 <html:p>PROTEIN_CLASS: </html:p>
2189 </notes>
2190 <listOfReactants>
2191 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
2192 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
2193 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
2194 </listOfReactants>
2195 <listOfProducts>
2196 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
2197 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
2198 <speciesReference species="M_succoa_c" stoichiometry="1.000000"/>
2199 </listOfProducts>
2200 </reaction>
2201 <reaction id="R_AKGt2r" name="R_2_oxoglutarate_reversible_transport_via_symport" reversible="true">
2202 <notes>
2203 <html:p>GENE_ASSOCIATION: b2587</html:p>
2204 <html:p>PROTEIN_ASSOCIATION: KgtPec</html:p>
2205 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
2206 <html:p>PROTEIN_CLASS: </html:p>
2207 </notes>
2208 <listOfReactants>
2209 <speciesReference species="M_akg_e" stoichiometry="1.000000"/>
2210 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
2211 </listOfReactants>
2212 <listOfProducts>
2213 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
2214 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2215 </listOfProducts>
2216 </reaction>
2217 <reaction id="R_ALAALAr" name="R_D_alanine_D_alanine_ligase__reversible_" reversible="true">
2218 <notes>
2219 <html:p>GENE_ASSOCIATION: ( b0381 or b0092 )</html:p>
2220 <html:p>PROTEIN_ASSOCIATION: ( DdlA ) or ( DdlB )</html:p>
2221 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
2222 <html:p>PROTEIN_CLASS: 6.3.2.4</html:p>
2223 </notes>
2224 <listOfReactants>
2225 <speciesReference species="M_ala_D_c" stoichiometry="2.000000"/>
2226 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
2227 </listOfReactants>
2228 <listOfProducts>
2229 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
2230 <speciesReference species="M_alaala_c" stoichiometry="1.000000"/>
2231 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2232 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
2233 </listOfProducts>
2234 </reaction>
2235 <reaction id="R_ALAR" name="R_alanine_racemase" reversible="true">
2236 <notes>
2237 <html:p>GENE_ASSOCIATION: b4053</html:p>
2238 <html:p>PROTEIN_ASSOCIATION: Alrec</html:p>
2239 <html:p>SUBSYSTEM: S_Alanine_and_Aspartate_Metabolism</html:p>
2240 <html:p>PROTEIN_CLASS: 5.1.1.1</html:p>
2241 </notes>
2242 <listOfReactants>
2243 <speciesReference species="M_ala_L_c" stoichiometry="1.000000"/>
2244 </listOfReactants>
2245 <listOfProducts>
2246 <speciesReference species="M_ala_D_c" stoichiometry="1.000000"/>
2247 </listOfProducts>
2248 </reaction>
2249 <reaction id="R_ALARi" name="R_alanine_racemase__irreversible_" reversible="false">
2250 <notes>
2251 <html:p>GENE_ASSOCIATION: b1190</html:p>
2252 <html:p>PROTEIN_ASSOCIATION: DadX</html:p>
2253 <html:p>SUBSYSTEM: S_Alanine_and_Aspartate_Metabolism</html:p>
2254 <html:p>PROTEIN_CLASS: 5.1.1.1</html:p>
2255 </notes>
2256 <listOfReactants>
2257 <speciesReference species="M_ala_L_c" stoichiometry="1.000000"/>
2258 </listOfReactants>
2259 <listOfProducts>
2260 <speciesReference species="M_ala_D_c" stoichiometry="1.000000"/>
2261 </listOfProducts>
2262 </reaction>
2263 <reaction id="R_ALATA_D2" name="R_D_alanine_transaminase" reversible="false">
2264 <notes>
2265 <html:p>GENE_ASSOCIATION: b2551</html:p>
2266 <html:p>PROTEIN_ASSOCIATION: GlyA</html:p>
2267 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
2268 <html:p>PROTEIN_CLASS: </html:p>
2269 </notes>
2270 <listOfReactants>
2271 <speciesReference species="M_ala_D_c" stoichiometry="1.000000"/>
2272 <speciesReference species="M_pydx5p_c" stoichiometry="1.000000"/>
2273 </listOfReactants>
2274 <listOfProducts>
2275 <speciesReference species="M_pyam5p_c" stoichiometry="1.000000"/>
2276 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
2277 </listOfProducts>
2278 </reaction>
2279 <reaction id="R_ALATA_L" name="R_L_alanine_transaminase" reversible="true">
2280 <notes>
2281 <html:p>GENE_ASSOCIATION: </html:p>
2282 <html:p>PROTEIN_ASSOCIATION: </html:p>
2283 <html:p>SUBSYSTEM: S_Alanine_and_Aspartate_Metabolism</html:p>
2284 <html:p>PROTEIN_CLASS: 2.6.1.2</html:p>
2285 </notes>
2286 <listOfReactants>
2287 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
2288 <speciesReference species="M_ala_L_c" stoichiometry="1.000000"/>
2289 </listOfReactants>
2290 <listOfProducts>
2291 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
2292 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
2293 </listOfProducts>
2294 </reaction>
2295 <reaction id="R_ALATA_L2" name="R_alanine_transaminase" reversible="false">
2296 <notes>
2297 <html:p>GENE_ASSOCIATION: b2551</html:p>
2298 <html:p>PROTEIN_ASSOCIATION: GlyA</html:p>
2299 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
2300 <html:p>PROTEIN_CLASS: </html:p>
2301 </notes>
2302 <listOfReactants>
2303 <speciesReference species="M_ala_L_c" stoichiometry="1.000000"/>
2304 <speciesReference species="M_pydx5p_c" stoichiometry="1.000000"/>
2305 </listOfReactants>
2306 <listOfProducts>
2307 <speciesReference species="M_pyam5p_c" stoichiometry="1.000000"/>
2308 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
2309 </listOfProducts>
2310 </reaction>
2311 <reaction id="R_ALAabc" name="R_L_alanine_transport_via_ABC_system" reversible="false">
2312 <notes>
2313 <html:p>GENE_ASSOCIATION: ( b3454 and b3455 and b3457 and b3460 and b3456 )</html:p>
2314 <html:p>PROTEIN_ASSOCIATION: ( LivF and LivG and LivH and LivJ and LivM )</html:p>
2315 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
2316 <html:p>PROTEIN_CLASS: </html:p>
2317 </notes>
2318 <listOfReactants>
2319 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
2320 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
2321 <speciesReference species="M_ala_L_e" stoichiometry="1.000000"/>
2322 </listOfReactants>
2323 <listOfProducts>
2324 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
2325 <speciesReference species="M_ala_L_c" stoichiometry="1.000000"/>
2326 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2327 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
2328 </listOfProducts>
2329 </reaction>
2330 <reaction id="R_ALAt2r" name="R_L_alanine_reversible_transport_via_proton_symport" reversible="true">
2331 <notes>
2332 <html:p>GENE_ASSOCIATION: ( b0007 or b4208 )</html:p>
2333 <html:p>PROTEIN_ASSOCIATION: ( YaaJ ) or ( CycAec )</html:p>
2334 <html:p>SUBSYSTEM: S_Putative_Transporters</html:p>
2335 <html:p>PROTEIN_CLASS: </html:p>
2336 </notes>
2337 <listOfReactants>
2338 <speciesReference species="M_ala_L_e" stoichiometry="1.000000"/>
2339 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
2340 </listOfReactants>
2341 <listOfProducts>
2342 <speciesReference species="M_ala_L_c" stoichiometry="1.000000"/>
2343 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2344 </listOfProducts>
2345 </reaction>
2346 <reaction id="R_ALCD19" name="R_alcohol_dehydrogenase__glycerol_" reversible="true">
2347 <notes>
2348 <html:p>GENE_ASSOCIATION: b0356</html:p>
2349 <html:p>PROTEIN_ASSOCIATION: AdhC</html:p>
2350 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
2351 <html:p>PROTEIN_CLASS: 1.1.1.1</html:p>
2352 </notes>
2353 <listOfReactants>
2354 <speciesReference species="M_glyald_c" stoichiometry="1.000000"/>
2355 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2356 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
2357 </listOfReactants>
2358 <listOfProducts>
2359 <speciesReference species="M_glyc_c" stoichiometry="1.000000"/>
2360 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
2361 </listOfProducts>
2362 </reaction>
2363 <reaction id="R_ALDD19x" name="R_aldehyde_dehydrogenase__phenylacetaldehyde__NAD_" reversible="false">
2364 <notes>
2365 <html:p>GENE_ASSOCIATION: b1385</html:p>
2366 <html:p>PROTEIN_ASSOCIATION: FeaB</html:p>
2367 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
2368 <html:p>PROTEIN_CLASS: 1.2.1.39</html:p>
2369 </notes>
2370 <listOfReactants>
2371 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
2372 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
2373 <speciesReference species="M_pacald_c" stoichiometry="1.000000"/>
2374 </listOfReactants>
2375 <listOfProducts>
2376 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
2377 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
2378 <speciesReference species="M_pac_c" stoichiometry="1.000000"/>
2379 </listOfProducts>
2380 </reaction>
2381 <reaction id="R_ALDD2x" name="R_aldehyde_dehydrogenase__acetaldehyde__NAD_" reversible="false">
2382 <notes>
2383 <html:p>GENE_ASSOCIATION: b1300</html:p>
2384 <html:p>PROTEIN_ASSOCIATION: AldH</html:p>
2385 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
2386 <html:p>PROTEIN_CLASS: 1.2.1.3</html:p>
2387 </notes>
2388 <listOfReactants>
2389 <speciesReference species="M_acald_c" stoichiometry="1.000000"/>
2390 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
2391 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
2392 </listOfReactants>
2393 <listOfProducts>
2394 <speciesReference species="M_ac_c" stoichiometry="1.000000"/>
2395 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
2396 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
2397 </listOfProducts>
2398 </reaction>
2399 <reaction id="R_ALLTAH" name="R_Allantoate_amidinohydrolase" reversible="false">
2400 <notes>
2401 <html:p>GENE_ASSOCIATION: b0516</html:p>
2402 <html:p>PROTEIN_ASSOCIATION: AllC</html:p>
2403 <html:p>SUBSYSTEM: S_Nitrogen_Metabolism</html:p>
2404 <html:p>PROTEIN_CLASS: 3.5.3.4</html:p>
2405 </notes>
2406 <listOfReactants>
2407 <speciesReference species="M_alltt_c" stoichiometry="1.000000"/>
2408 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
2409 </listOfReactants>
2410 <listOfProducts>
2411 <speciesReference species="M_urdglyc_c" stoichiometry="1.000000"/>
2412 <speciesReference species="M_urea_c" stoichiometry="1.000000"/>
2413 </listOfProducts>
2414 </reaction>
2415 <reaction id="R_ALLTN" name="R_allantoinase" reversible="false">
2416 <notes>
2417 <html:p>GENE_ASSOCIATION: b0512</html:p>
2418 <html:p>PROTEIN_ASSOCIATION: AllB</html:p>
2419 <html:p>SUBSYSTEM: S_Nitrogen_Metabolism</html:p>
2420 <html:p>PROTEIN_CLASS: 3.5.2.5</html:p>
2421 </notes>
2422 <listOfReactants>
2423 <speciesReference species="M_alltn_c" stoichiometry="1.000000"/>
2424 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
2425 </listOfReactants>
2426 <listOfProducts>
2427 <speciesReference species="M_alltt_c" stoichiometry="1.000000"/>
2428 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2429 </listOfProducts>
2430 </reaction>
2431 <reaction id="R_ALLTNt2r" name="R_allantoin_transport_in_via_proton_symport" reversible="true">
2432 <notes>
2433 <html:p>GENE_ASSOCIATION: b0511</html:p>
2434 <html:p>PROTEIN_ASSOCIATION: AllP</html:p>
2435 <html:p>SUBSYSTEM: S_Putative_Transporters</html:p>
2436 <html:p>PROTEIN_CLASS: </html:p>
2437 </notes>
2438 <listOfReactants>
2439 <speciesReference species="M_alltn_e" stoichiometry="1.000000"/>
2440 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
2441 </listOfReactants>
2442 <listOfProducts>
2443 <speciesReference species="M_alltn_c" stoichiometry="1.000000"/>
2444 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2445 </listOfProducts>
2446 </reaction>
2447 <reaction id="R_ALTRH" name="R_altronate_hydrolase" reversible="false">
2448 <notes>
2449 <html:p>GENE_ASSOCIATION: b3091</html:p>
2450 <html:p>PROTEIN_ASSOCIATION: UxaA</html:p>
2451 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
2452 <html:p>PROTEIN_CLASS: 4.2.1.7</html:p>
2453 </notes>
2454 <listOfReactants>
2455 <speciesReference species="M_altrn_c" stoichiometry="1.000000"/>
2456 </listOfReactants>
2457 <listOfProducts>
2458 <speciesReference species="M_2ddglcn_c" stoichiometry="1.000000"/>
2459 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
2460 </listOfProducts>
2461 </reaction>
2462 <reaction id="R_AMALT1" name="R_Amylomaltase__maltotriose_" reversible="false">
2463 <notes>
2464 <html:p>GENE_ASSOCIATION: b3416</html:p>
2465 <html:p>PROTEIN_ASSOCIATION: MalQ</html:p>
2466 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
2467 <html:p>PROTEIN_CLASS: 2.4.1.25</html:p>
2468 </notes>
2469 <listOfReactants>
2470 <speciesReference species="M_malt_c" stoichiometry="1.000000"/>
2471 <speciesReference species="M_malttr_c" stoichiometry="1.000000"/>
2472 </listOfReactants>
2473 <listOfProducts>
2474 <speciesReference species="M_glc_D_c" stoichiometry="1.000000"/>
2475 <speciesReference species="M_maltttr_c" stoichiometry="1.000000"/>
2476 </listOfProducts>
2477 </reaction>
2478 <reaction id="R_AMALT2" name="R_Amylomaltase__maltotetraose_" reversible="false">
2479 <notes>
2480 <html:p>GENE_ASSOCIATION: b3416</html:p>
2481 <html:p>PROTEIN_ASSOCIATION: MalQ</html:p>
2482 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
2483 <html:p>PROTEIN_CLASS: 2.4.1.25</html:p>
2484 </notes>
2485 <listOfReactants>
2486 <speciesReference species="M_malt_c" stoichiometry="1.000000"/>
2487 <speciesReference species="M_maltttr_c" stoichiometry="1.000000"/>
2488 </listOfReactants>
2489 <listOfProducts>
2490 <speciesReference species="M_glc_D_c" stoichiometry="1.000000"/>
2491 <speciesReference species="M_maltpt_c" stoichiometry="1.000000"/>
2492 </listOfProducts>
2493 </reaction>
2494 <reaction id="R_AMALT3" name="R_Amylomaltase__maltopentaose_" reversible="false">
2495 <notes>
2496 <html:p>GENE_ASSOCIATION: b3416</html:p>
2497 <html:p>PROTEIN_ASSOCIATION: MalQ</html:p>
2498 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
2499 <html:p>PROTEIN_CLASS: 2.4.1.25</html:p>
2500 </notes>
2501 <listOfReactants>
2502 <speciesReference species="M_malt_c" stoichiometry="1.000000"/>
2503 <speciesReference species="M_maltpt_c" stoichiometry="1.000000"/>
2504 </listOfReactants>
2505 <listOfProducts>
2506 <speciesReference species="M_glc_D_c" stoichiometry="1.000000"/>
2507 <speciesReference species="M_malthx_c" stoichiometry="1.000000"/>
2508 </listOfProducts>
2509 </reaction>
2510 <reaction id="R_AMALT4" name="R_Amylomaltase__maltohexaose_" reversible="false">
2511 <notes>
2512 <html:p>GENE_ASSOCIATION: b3416</html:p>
2513 <html:p>PROTEIN_ASSOCIATION: MalQ</html:p>
2514 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
2515 <html:p>PROTEIN_CLASS: 2.4.1.25</html:p>
2516 </notes>
2517 <listOfReactants>
2518 <speciesReference species="M_malt_c" stoichiometry="1.000000"/>
2519 <speciesReference species="M_malthx_c" stoichiometry="1.000000"/>
2520 </listOfReactants>
2521 <listOfProducts>
2522 <speciesReference species="M_glc_D_c" stoichiometry="1.000000"/>
2523 <speciesReference species="M_malthp_c" stoichiometry="1.000000"/>
2524 </listOfProducts>
2525 </reaction>
2526 <reaction id="R_AMANAPE" name="R_N_acetylmannosamine_6_phosphate_epimerase" reversible="false">
2527 <notes>
2528 <html:p>GENE_ASSOCIATION: b3223</html:p>
2529 <html:p>PROTEIN_ASSOCIATION: NanE</html:p>
2530 <html:p>SUBSYSTEM: S_Putative</html:p>
2531 <html:p>PROTEIN_CLASS: </html:p>
2532 </notes>
2533 <listOfReactants>
2534 <speciesReference species="M_acmanap_c" stoichiometry="1.000000"/>
2535 </listOfReactants>
2536 <listOfProducts>
2537 <speciesReference species="M_acgam6p_c" stoichiometry="1.000000"/>
2538 </listOfProducts>
2539 </reaction>
2540 <reaction id="R_AMANK" name="R_N_acetyl_D_mannosamine_kinase" reversible="false">
2541 <notes>
2542 <html:p>GENE_ASSOCIATION: b3222</html:p>
2543 <html:p>PROTEIN_ASSOCIATION: NanK</html:p>
2544 <html:p>SUBSYSTEM: S_Putative</html:p>
2545 <html:p>PROTEIN_CLASS: 2.7.1.60</html:p>
2546 </notes>
2547 <listOfReactants>
2548 <speciesReference species="M_acmana_c" stoichiometry="1.000000"/>
2549 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
2550 </listOfReactants>
2551 <listOfProducts>
2552 <speciesReference species="M_acmanap_c" stoichiometry="1.000000"/>
2553 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
2554 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2555 </listOfProducts>
2556 </reaction>
2557 <reaction id="R_AMAOTr" name="R_adenosylmethionine_8_amino_7_oxononanoate_transaminase" reversible="true">
2558 <notes>
2559 <html:p>GENE_ASSOCIATION: b0774</html:p>
2560 <html:p>PROTEIN_ASSOCIATION: BioAec</html:p>
2561 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
2562 <html:p>PROTEIN_CLASS: 2.6.1.62</html:p>
2563 </notes>
2564 <listOfReactants>
2565 <speciesReference species="M_8aonn_c" stoichiometry="1.000000"/>
2566 <speciesReference species="M_amet_c" stoichiometry="1.000000"/>
2567 </listOfReactants>
2568 <listOfProducts>
2569 <speciesReference species="M_amob_c" stoichiometry="1.000000"/>
2570 <speciesReference species="M_dann_c" stoichiometry="1.000000"/>
2571 </listOfProducts>
2572 </reaction>
2573 <reaction id="R_AMMQT8_2" name="R_S_adenosylmethione2_demethylmenaquinone_methyltransferase" reversible="false">
2574 <notes>
2575 <html:p>GENE_ASSOCIATION: b3929</html:p>
2576 <html:p>PROTEIN_ASSOCIATION: MenG</html:p>
2577 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
2578 <html:p>PROTEIN_CLASS: </html:p>
2579 </notes>
2580 <listOfReactants>
2581 <speciesReference species="M_2dmmq8_c" stoichiometry="1.000000"/>
2582 <speciesReference species="M_amet_c" stoichiometry="1.000000"/>
2583 </listOfReactants>
2584 <listOfProducts>
2585 <speciesReference species="M_ahcys_c" stoichiometry="1.000000"/>
2586 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2587 <speciesReference species="M_mqn8_c" stoichiometry="1.000000"/>
2588 </listOfProducts>
2589 </reaction>
2590 <reaction id="R_AMPMS" name="R_4_amino_2_methyl_5_phosphomethylpyrimidine_synthetase" reversible="false">
2591 <notes>
2592 <html:p>GENE_ASSOCIATION: b3994</html:p>
2593 <html:p>PROTEIN_ASSOCIATION: ThiC</html:p>
2594 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
2595 <html:p>PROTEIN_CLASS: </html:p>
2596 </notes>
2597 <listOfReactants>
2598 <speciesReference species="M_air_c" stoichiometry="1.000000"/>
2599 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
2600 </listOfReactants>
2601 <listOfProducts>
2602 <speciesReference species="M_4ampm_c" stoichiometry="1.000000"/>
2603 <speciesReference species="M_for_c" stoichiometry="2.000000"/>
2604 <speciesReference species="M_h_c" stoichiometry="4.000000"/>
2605 </listOfProducts>
2606 </reaction>
2607 <reaction id="R_AMPN" name="R_AMP_nucleosidase" reversible="false">
2608 <notes>
2609 <html:p>GENE_ASSOCIATION: b1982</html:p>
2610 <html:p>PROTEIN_ASSOCIATION: Amn</html:p>
2611 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
2612 <html:p>PROTEIN_CLASS: 3.2.2.4</html:p>
2613 </notes>
2614 <listOfReactants>
2615 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
2616 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
2617 </listOfReactants>
2618 <listOfProducts>
2619 <speciesReference species="M_ade_c" stoichiometry="1.000000"/>
2620 <speciesReference species="M_r5p_c" stoichiometry="1.000000"/>
2621 </listOfProducts>
2622 </reaction>
2623 <reaction id="R_ANPRT" name="R_anthranilate_phosphoribosyltransferase" reversible="false">
2624 <notes>
2625 <html:p>GENE_ASSOCIATION: b1263</html:p>
2626 <html:p>PROTEIN_ASSOCIATION: TrpDec</html:p>
2627 <html:p>SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism</html:p>
2628 <html:p>PROTEIN_CLASS: 2.4.2.18</html:p>
2629 </notes>
2630 <listOfReactants>
2631 <speciesReference species="M_anth_c" stoichiometry="1.000000"/>
2632 <speciesReference species="M_prpp_c" stoichiometry="1.000000"/>
2633 </listOfReactants>
2634 <listOfProducts>
2635 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
2636 <speciesReference species="M_pran_c" stoichiometry="1.000000"/>
2637 </listOfProducts>
2638 </reaction>
2639 <reaction id="R_ANS" name="R_anthranilate_synthase" reversible="false">
2640 <notes>
2641 <html:p>GENE_ASSOCIATION: ( b1263 and b1264 )</html:p>
2642 <html:p>PROTEIN_ASSOCIATION: ( TrpDec and TrpEec )</html:p>
2643 <html:p>SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism</html:p>
2644 <html:p>PROTEIN_CLASS: 4.1.3.27</html:p>
2645 </notes>
2646 <listOfReactants>
2647 <speciesReference species="M_chor_c" stoichiometry="1.000000"/>
2648 <speciesReference species="M_gln_L_c" stoichiometry="1.000000"/>
2649 </listOfReactants>
2650 <listOfProducts>
2651 <speciesReference species="M_anth_c" stoichiometry="1.000000"/>
2652 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
2653 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2654 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
2655 </listOfProducts>
2656 </reaction>
2657 <reaction id="R_AOXSr" name="R_8_amino_7_oxononanoate_synthase" reversible="true">
2658 <notes>
2659 <html:p>GENE_ASSOCIATION: b0776</html:p>
2660 <html:p>PROTEIN_ASSOCIATION: BioF</html:p>
2661 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
2662 <html:p>PROTEIN_CLASS: 2.3.1.47</html:p>
2663 </notes>
2664 <listOfReactants>
2665 <speciesReference species="M_ala_L_c" stoichiometry="1.000000"/>
2666 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2667 <speciesReference species="M_pmcoa_c" stoichiometry="1.000000"/>
2668 </listOfReactants>
2669 <listOfProducts>
2670 <speciesReference species="M_8aonn_c" stoichiometry="1.000000"/>
2671 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
2672 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
2673 </listOfProducts>
2674 </reaction>
2675 <reaction id="R_AP4AH" name="R_Ap4A_hydrolase" reversible="false">
2676 <notes>
2677 <html:p>GENE_ASSOCIATION: b0049</html:p>
2678 <html:p>PROTEIN_ASSOCIATION: ApaH</html:p>
2679 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
2680 <html:p>PROTEIN_CLASS: 3.6.1.41</html:p>
2681 </notes>
2682 <listOfReactants>
2683 <speciesReference species="M_ap4a_c" stoichiometry="1.000000"/>
2684 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
2685 </listOfReactants>
2686 <listOfProducts>
2687 <speciesReference species="M_adp_c" stoichiometry="2.000000"/>
2688 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
2689 </listOfProducts>
2690 </reaction>
2691 <reaction id="R_AP5AH" name="R_Ap5A_hydrolase" reversible="false">
2692 <notes>
2693 <html:p>GENE_ASSOCIATION: b0049</html:p>
2694 <html:p>PROTEIN_ASSOCIATION: ApaH</html:p>
2695 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
2696 <html:p>PROTEIN_CLASS: </html:p>
2697 </notes>
2698 <listOfReactants>
2699 <speciesReference species="M_ap5a_c" stoichiometry="1.000000"/>
2700 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
2701 </listOfReactants>
2702 <listOfProducts>
2703 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
2704 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
2705 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
2706 </listOfProducts>
2707 </reaction>
2708 <reaction id="R_APRAUR" name="R_5_amino_6__5_phosphoribosylamino_uracil_reductase" reversible="false">
2709 <notes>
2710 <html:p>GENE_ASSOCIATION: b0414</html:p>
2711 <html:p>PROTEIN_ASSOCIATION: RibDec</html:p>
2712 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
2713 <html:p>PROTEIN_CLASS: 1.1.1.193</html:p>
2714 </notes>
2715 <listOfReactants>
2716 <speciesReference species="M_5apru_c" stoichiometry="1.000000"/>
2717 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2718 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
2719 </listOfReactants>
2720 <listOfProducts>
2721 <speciesReference species="M_5aprbu_c" stoichiometry="1.000000"/>
2722 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
2723 </listOfProducts>
2724 </reaction>
2725 <reaction id="R_ARAI" name="R_L_arabinose_isomerase" reversible="true">
2726 <notes>
2727 <html:p>GENE_ASSOCIATION: b0062</html:p>
2728 <html:p>PROTEIN_ASSOCIATION: AraA</html:p>
2729 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
2730 <html:p>PROTEIN_CLASS: 5.3.1.4</html:p>
2731 </notes>
2732 <listOfReactants>
2733 <speciesReference species="M_arab_L_c" stoichiometry="1.000000"/>
2734 </listOfReactants>
2735 <listOfProducts>
2736 <speciesReference species="M_rbl_L_c" stoichiometry="1.000000"/>
2737 </listOfProducts>
2738 </reaction>
2739 <reaction id="R_ARBabc" name="R_L_arabinose_transport_via_ABC_system" reversible="false">
2740 <notes>
2741 <html:p>GENE_ASSOCIATION: ( b1901 and b1900 and ( b1898 and b1899 ) )</html:p>
2742 <html:p>PROTEIN_ASSOCIATION: ( AraF and AraG and AraH )</html:p>
2743 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
2744 <html:p>PROTEIN_CLASS: </html:p>
2745 </notes>
2746 <listOfReactants>
2747 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
2748 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
2749 <speciesReference species="M_arab_L_e" stoichiometry="1.000000"/>
2750 </listOfReactants>
2751 <listOfProducts>
2752 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
2753 <speciesReference species="M_arab_L_c" stoichiometry="1.000000"/>
2754 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2755 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
2756 </listOfProducts>
2757 </reaction>
2758 <reaction id="R_ARBt2r" name="R_L_arabinose_transport_via_proton_symport" reversible="true">
2759 <notes>
2760 <html:p>GENE_ASSOCIATION: b2841</html:p>
2761 <html:p>PROTEIN_ASSOCIATION: AraE</html:p>
2762 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
2763 <html:p>PROTEIN_CLASS: </html:p>
2764 </notes>
2765 <listOfReactants>
2766 <speciesReference species="M_arab_L_e" stoichiometry="1.000000"/>
2767 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
2768 </listOfReactants>
2769 <listOfProducts>
2770 <speciesReference species="M_arab_L_c" stoichiometry="1.000000"/>
2771 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2772 </listOfProducts>
2773 </reaction>
2774 <reaction id="R_ARGDC" name="R_arginine_decarboxylase" reversible="false">
2775 <notes>
2776 <html:p>GENE_ASSOCIATION: ( b2938 or b4117 )</html:p>
2777 <html:p>PROTEIN_ASSOCIATION: ( SpeA ) or ( AdiA )</html:p>
2778 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
2779 <html:p>PROTEIN_CLASS: 4.1.1.19</html:p>
2780 </notes>
2781 <listOfReactants>
2782 <speciesReference species="M_arg_L_c" stoichiometry="1.000000"/>
2783 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2784 </listOfReactants>
2785 <listOfProducts>
2786 <speciesReference species="M_agm_c" stoichiometry="1.000000"/>
2787 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
2788 </listOfProducts>
2789 </reaction>
2790 <reaction id="R_ARGORNt7" name="R_arginineornithine_antiporter" reversible="true">
2791 <notes>
2792 <html:p>GENE_ASSOCIATION: b1605</html:p>
2793 <html:p>PROTEIN_ASSOCIATION: ArcD</html:p>
2794 <html:p>SUBSYSTEM: S_Putative_Transporters</html:p>
2795 <html:p>PROTEIN_CLASS: </html:p>
2796 </notes>
2797 <listOfReactants>
2798 <speciesReference species="M_orn_c" stoichiometry="1.000000"/>
2799 <speciesReference species="M_arg_L_e" stoichiometry="1.000000"/>
2800 </listOfReactants>
2801 <listOfProducts>
2802 <speciesReference species="M_arg_L_c" stoichiometry="1.000000"/>
2803 <speciesReference species="M_orn_e" stoichiometry="1.000000"/>
2804 </listOfProducts>
2805 </reaction>
2806 <reaction id="R_ARGSL" name="R_argininosuccinate_lyase" reversible="true">
2807 <notes>
2808 <html:p>GENE_ASSOCIATION: b3960</html:p>
2809 <html:p>PROTEIN_ASSOCIATION: ArgH</html:p>
2810 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
2811 <html:p>PROTEIN_CLASS: 4.3.2.1</html:p>
2812 </notes>
2813 <listOfReactants>
2814 <speciesReference species="M_argsuc_c" stoichiometry="1.000000"/>
2815 </listOfReactants>
2816 <listOfProducts>
2817 <speciesReference species="M_arg_L_c" stoichiometry="1.000000"/>
2818 <speciesReference species="M_fum_c" stoichiometry="1.000000"/>
2819 </listOfProducts>
2820 </reaction>
2821 <reaction id="R_ARGSS" name="R_argininosuccinate_synthase" reversible="false">
2822 <notes>
2823 <html:p>GENE_ASSOCIATION: b3172</html:p>
2824 <html:p>PROTEIN_ASSOCIATION: ArgG</html:p>
2825 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
2826 <html:p>PROTEIN_CLASS: 6.3.4.5</html:p>
2827 </notes>
2828 <listOfReactants>
2829 <speciesReference species="M_asp_L_c" stoichiometry="1.000000"/>
2830 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
2831 <speciesReference species="M_citr_L_c" stoichiometry="1.000000"/>
2832 </listOfReactants>
2833 <listOfProducts>
2834 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
2835 <speciesReference species="M_argsuc_c" stoichiometry="1.000000"/>
2836 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2837 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
2838 </listOfProducts>
2839 </reaction>
2840 <reaction id="R_ARGabc" name="R_L_arginine_transport_via_ABC_system" reversible="false">
2841 <notes>
2842 <html:p>GENE_ASSOCIATION: ( ( b2310 and b2307 and b2306 and b2308 ) or ( b0860 and b0861 and b0864 and b0862 ) )</html:p>
2843 <html:p>PROTEIN_ASSOCIATION: ( ArgT and HisM and HisP and HisQ ) or ( ArtJ and ArtM and ArtP and ArtQ )</html:p>
2844 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
2845 <html:p>PROTEIN_CLASS: </html:p>
2846 </notes>
2847 <listOfReactants>
2848 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
2849 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
2850 <speciesReference species="M_arg_L_e" stoichiometry="1.000000"/>
2851 </listOfReactants>
2852 <listOfProducts>
2853 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
2854 <speciesReference species="M_arg_L_c" stoichiometry="1.000000"/>
2855 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2856 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
2857 </listOfProducts>
2858 </reaction>
2859 <reaction id="R_ASAD" name="R_aspartate_semialdehyde_dehydrogenase" reversible="true">
2860 <notes>
2861 <html:p>GENE_ASSOCIATION: b3433</html:p>
2862 <html:p>PROTEIN_ASSOCIATION: Asd</html:p>
2863 <html:p>SUBSYSTEM: S_Threonine_and_Lysine_Metabolism</html:p>
2864 <html:p>PROTEIN_CLASS: 1.2.1.11</html:p>
2865 </notes>
2866 <listOfReactants>
2867 <speciesReference species="M_aspsa_c" stoichiometry="1.000000"/>
2868 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
2869 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
2870 </listOfReactants>
2871 <listOfProducts>
2872 <speciesReference species="M_4pasp_c" stoichiometry="1.000000"/>
2873 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2874 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
2875 </listOfProducts>
2876 </reaction>
2877 <reaction id="R_ASNN" name="R_L_asparaginase" reversible="false">
2878 <notes>
2879 <html:p>GENE_ASSOCIATION: ( b1767 or b2957 or b0828 )</html:p>
2880 <html:p>PROTEIN_ASSOCIATION: ( AnsA ) or ( AnsB ) or ( YbiK )</html:p>
2881 <html:p>SUBSYSTEM: S_Alanine_and_Aspartate_Metabolism</html:p>
2882 <html:p>PROTEIN_CLASS: 3.5.1.1</html:p>
2883 </notes>
2884 <listOfReactants>
2885 <speciesReference species="M_asn_L_c" stoichiometry="1.000000"/>
2886 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
2887 </listOfReactants>
2888 <listOfProducts>
2889 <speciesReference species="M_asp_L_c" stoichiometry="1.000000"/>
2890 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
2891 </listOfProducts>
2892 </reaction>
2893 <reaction id="R_ASNS1" name="R_asparagine_synthase__glutamine_hydrolysing_" reversible="false">
2894 <notes>
2895 <html:p>GENE_ASSOCIATION: b0674</html:p>
2896 <html:p>PROTEIN_ASSOCIATION: AsnB</html:p>
2897 <html:p>SUBSYSTEM: S_Alanine_and_Aspartate_Metabolism</html:p>
2898 <html:p>PROTEIN_CLASS: 6.3.5.4</html:p>
2899 </notes>
2900 <listOfReactants>
2901 <speciesReference species="M_asp_L_c" stoichiometry="1.000000"/>
2902 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
2903 <speciesReference species="M_gln_L_c" stoichiometry="1.000000"/>
2904 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
2905 </listOfReactants>
2906 <listOfProducts>
2907 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
2908 <speciesReference species="M_asn_L_c" stoichiometry="1.000000"/>
2909 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
2910 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2911 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
2912 </listOfProducts>
2913 </reaction>
2914 <reaction id="R_ASNS2" name="R_asparagine_synthetase" reversible="false">
2915 <notes>
2916 <html:p>GENE_ASSOCIATION: b3744</html:p>
2917 <html:p>PROTEIN_ASSOCIATION: AsnA</html:p>
2918 <html:p>SUBSYSTEM: S_Alanine_and_Aspartate_Metabolism</html:p>
2919 <html:p>PROTEIN_CLASS: 6.3.1.1</html:p>
2920 </notes>
2921 <listOfReactants>
2922 <speciesReference species="M_asp_L_c" stoichiometry="1.000000"/>
2923 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
2924 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
2925 </listOfReactants>
2926 <listOfProducts>
2927 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
2928 <speciesReference species="M_asn_L_c" stoichiometry="1.000000"/>
2929 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2930 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
2931 </listOfProducts>
2932 </reaction>
2933 <reaction id="R_ASNabc" name="R_L_asparagine_transport_via_ABC_system" reversible="false">
2934 <notes>
2935 <html:p>GENE_ASSOCIATION: </html:p>
2936 <html:p>PROTEIN_ASSOCIATION: </html:p>
2937 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
2938 <html:p>PROTEIN_CLASS: </html:p>
2939 </notes>
2940 <listOfReactants>
2941 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
2942 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
2943 <speciesReference species="M_asn_L_e" stoichiometry="1.000000"/>
2944 </listOfReactants>
2945 <listOfProducts>
2946 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
2947 <speciesReference species="M_asn_L_c" stoichiometry="1.000000"/>
2948 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2949 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
2950 </listOfProducts>
2951 </reaction>
2952 <reaction id="R_ASNt2r" name="R_L_asparagine_reversible_transport_via_proton_symport" reversible="true">
2953 <notes>
2954 <html:p>GENE_ASSOCIATION: </html:p>
2955 <html:p>PROTEIN_ASSOCIATION: </html:p>
2956 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
2957 <html:p>PROTEIN_CLASS: </html:p>
2958 </notes>
2959 <listOfReactants>
2960 <speciesReference species="M_asn_L_e" stoichiometry="1.000000"/>
2961 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
2962 </listOfReactants>
2963 <listOfProducts>
2964 <speciesReference species="M_asn_L_c" stoichiometry="1.000000"/>
2965 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2966 </listOfProducts>
2967 </reaction>
2968 <reaction id="R_ASP1DC" name="R_aspartate_1_decarboxylase" reversible="false">
2969 <notes>
2970 <html:p>GENE_ASSOCIATION: b0131</html:p>
2971 <html:p>PROTEIN_ASSOCIATION: PanD</html:p>
2972 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
2973 <html:p>PROTEIN_CLASS: 4.1.1.11</html:p>
2974 </notes>
2975 <listOfReactants>
2976 <speciesReference species="M_asp_L_c" stoichiometry="1.000000"/>
2977 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2978 </listOfReactants>
2979 <listOfProducts>
2980 <speciesReference species="M_ala_B_c" stoichiometry="1.000000"/>
2981 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
2982 </listOfProducts>
2983 </reaction>
2984 <reaction id="R_ASPCT" name="R_aspartate_carbamoyltransferase" reversible="false">
2985 <notes>
2986 <html:p>GENE_ASSOCIATION: ( b4244 and b4245 )</html:p>
2987 <html:p>PROTEIN_ASSOCIATION: PyrBec</html:p>
2988 <html:p>SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis</html:p>
2989 <html:p>PROTEIN_CLASS: 2.1.3.2</html:p>
2990 </notes>
2991 <listOfReactants>
2992 <speciesReference species="M_asp_L_c" stoichiometry="1.000000"/>
2993 <speciesReference species="M_cbp_c" stoichiometry="1.000000"/>
2994 </listOfReactants>
2995 <listOfProducts>
2996 <speciesReference species="M_cbasp_c" stoichiometry="1.000000"/>
2997 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
2998 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
2999 </listOfProducts>
3000 </reaction>
3001 <reaction id="R_ASPK" name="R_aspartate_kinase" reversible="true">
3002 <notes>
3003 <html:p>GENE_ASSOCIATION: ( b0002 or b3940 or b4024 )</html:p>
3004 <html:p>PROTEIN_ASSOCIATION: ( ThrA ) or ( MetL ) or ( LysCec )</html:p>
3005 <html:p>SUBSYSTEM: S_Threonine_and_Lysine_Metabolism</html:p>
3006 <html:p>PROTEIN_CLASS: 2.7.2.4</html:p>
3007 </notes>
3008 <listOfReactants>
3009 <speciesReference species="M_asp_L_c" stoichiometry="1.000000"/>
3010 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
3011 </listOfReactants>
3012 <listOfProducts>
3013 <speciesReference species="M_4pasp_c" stoichiometry="1.000000"/>
3014 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
3015 </listOfProducts>
3016 </reaction>
3017 <reaction id="R_ASPO3" name="R_L_aspartate_oxidase" reversible="false">
3018 <notes>
3019 <html:p>GENE_ASSOCIATION: b2574</html:p>
3020 <html:p>PROTEIN_ASSOCIATION: NadB</html:p>
3021 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
3022 <html:p>PROTEIN_CLASS: </html:p>
3023 </notes>
3024 <listOfReactants>
3025 <speciesReference species="M_asp_L_c" stoichiometry="1.000000"/>
3026 <speciesReference species="M_q8_c" stoichiometry="1.000000"/>
3027 </listOfReactants>
3028 <listOfProducts>
3029 <speciesReference species="M_iasp_c" stoichiometry="1.000000"/>
3030 <speciesReference species="M_q8h2_c" stoichiometry="1.000000"/>
3031 </listOfProducts>
3032 </reaction>
3033 <reaction id="R_ASPO4" name="R_L_aspartate_oxidase" reversible="false">
3034 <notes>
3035 <html:p>GENE_ASSOCIATION: b2574</html:p>
3036 <html:p>PROTEIN_ASSOCIATION: NadB</html:p>
3037 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
3038 <html:p>PROTEIN_CLASS: </html:p>
3039 </notes>
3040 <listOfReactants>
3041 <speciesReference species="M_asp_L_c" stoichiometry="1.000000"/>
3042 <speciesReference species="M_mqn8_c" stoichiometry="1.000000"/>
3043 </listOfReactants>
3044 <listOfProducts>
3045 <speciesReference species="M_iasp_c" stoichiometry="1.000000"/>
3046 <speciesReference species="M_mql8_c" stoichiometry="1.000000"/>
3047 </listOfProducts>
3048 </reaction>
3049 <reaction id="R_ASPO5" name="R_L_aspartate_oxidase" reversible="false">
3050 <notes>
3051 <html:p>GENE_ASSOCIATION: b2574</html:p>
3052 <html:p>PROTEIN_ASSOCIATION: NadB</html:p>
3053 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
3054 <html:p>PROTEIN_CLASS: </html:p>
3055 </notes>
3056 <listOfReactants>
3057 <speciesReference species="M_asp_L_c" stoichiometry="1.000000"/>
3058 <speciesReference species="M_fum_c" stoichiometry="1.000000"/>
3059 </listOfReactants>
3060 <listOfProducts>
3061 <speciesReference species="M_iasp_c" stoichiometry="1.000000"/>
3062 <speciesReference species="M_succ_c" stoichiometry="1.000000"/>
3063 </listOfProducts>
3064 </reaction>
3065 <reaction id="R_ASPO6" name="R_L_aspartate_oxidase" reversible="false">
3066 <notes>
3067 <html:p>GENE_ASSOCIATION: b2574</html:p>
3068 <html:p>PROTEIN_ASSOCIATION: NadB</html:p>
3069 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
3070 <html:p>PROTEIN_CLASS: </html:p>
3071 </notes>
3072 <listOfReactants>
3073 <speciesReference species="M_asp_L_c" stoichiometry="1.000000"/>
3074 <speciesReference species="M_o2_c" stoichiometry="1.000000"/>
3075 </listOfReactants>
3076 <listOfProducts>
3077 <speciesReference species="M_h2o2_c" stoichiometry="1.000000"/>
3078 <speciesReference species="M_iasp_c" stoichiometry="1.000000"/>
3079 </listOfProducts>
3080 </reaction>
3081 <reaction id="R_ASPT" name="R_L_aspartase" reversible="false">
3082 <notes>
3083 <html:p>GENE_ASSOCIATION: b4139</html:p>
3084 <html:p>PROTEIN_ASSOCIATION: AspA</html:p>
3085 <html:p>SUBSYSTEM: S_Alanine_and_Aspartate_Metabolism</html:p>
3086 <html:p>PROTEIN_CLASS: 4.3.1.1</html:p>
3087 </notes>
3088 <listOfReactants>
3089 <speciesReference species="M_asp_L_c" stoichiometry="1.000000"/>
3090 </listOfReactants>
3091 <listOfProducts>
3092 <speciesReference species="M_fum_c" stoichiometry="1.000000"/>
3093 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
3094 </listOfProducts>
3095 </reaction>
3096 <reaction id="R_ASPTA" name="R_aspartate_transaminase" reversible="true">
3097 <notes>
3098 <html:p>GENE_ASSOCIATION: b0928</html:p>
3099 <html:p>PROTEIN_ASSOCIATION: AspC</html:p>
3100 <html:p>SUBSYSTEM: S_Alanine_and_Aspartate_Metabolism</html:p>
3101 <html:p>PROTEIN_CLASS: 2.6.1.1</html:p>
3102 </notes>
3103 <listOfReactants>
3104 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
3105 <speciesReference species="M_asp_L_c" stoichiometry="1.000000"/>
3106 </listOfReactants>
3107 <listOfProducts>
3108 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
3109 <speciesReference species="M_oaa_c" stoichiometry="1.000000"/>
3110 </listOfProducts>
3111 </reaction>
3112 <reaction id="R_ASPabc" name="R_L_aspartate_transport_via_ABC_system" reversible="false">
3113 <notes>
3114 <html:p>GENE_ASSOCIATION: ( b0655 and b0654 and b0653 and b0652 )</html:p>
3115 <html:p>PROTEIN_ASSOCIATION: ( GltI and GltJ and GltK and GltL )</html:p>
3116 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
3117 <html:p>PROTEIN_CLASS: </html:p>
3118 </notes>
3119 <listOfReactants>
3120 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
3121 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
3122 <speciesReference species="M_asp_L_e" stoichiometry="1.000000"/>
3123 </listOfReactants>
3124 <listOfProducts>
3125 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
3126 <speciesReference species="M_asp_L_c" stoichiometry="1.000000"/>
3127 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
3128 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
3129 </listOfProducts>
3130 </reaction>
3131 <reaction id="R_ASPt2" name="R_L_aspartate_transport_in_via_proton_symport" reversible="false">
3132 <notes>
3133 <html:p>GENE_ASSOCIATION: b4077</html:p>
3134 <html:p>PROTEIN_ASSOCIATION: GltP</html:p>
3135 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
3136 <html:p>PROTEIN_CLASS: </html:p>
3137 </notes>
3138 <listOfReactants>
3139 <speciesReference species="M_asp_L_e" stoichiometry="1.000000"/>
3140 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
3141 </listOfReactants>
3142 <listOfProducts>
3143 <speciesReference species="M_asp_L_c" stoichiometry="1.000000"/>
3144 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
3145 </listOfProducts>
3146 </reaction>
3147 <reaction id="R_ASPt2_2" name="R_Aspartate_transport_via_proton_symport__2_H_" reversible="false">
3148 <notes>
3149 <html:p>GENE_ASSOCIATION: b3528</html:p>
3150 <html:p>PROTEIN_ASSOCIATION: DctA</html:p>
3151 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
3152 <html:p>PROTEIN_CLASS: </html:p>
3153 </notes>
3154 <listOfReactants>
3155 <speciesReference species="M_asp_L_e" stoichiometry="1.000000"/>
3156 <speciesReference species="M_h_e" stoichiometry="2.000000"/>
3157 </listOfReactants>
3158 <listOfProducts>
3159 <speciesReference species="M_asp_L_c" stoichiometry="1.000000"/>
3160 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
3161 </listOfProducts>
3162 </reaction>
3163 <reaction id="R_ASPt2_3" name="R_L_asparate_transport_via_proton_symport__3_H_" reversible="false">
3164 <notes>
3165 <html:p>GENE_ASSOCIATION: ( b4138 or b4123 )</html:p>
3166 <html:p>PROTEIN_ASSOCIATION: ( DcuA ) or ( DcuB )</html:p>
3167 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
3168 <html:p>PROTEIN_CLASS: </html:p>
3169 </notes>
3170 <listOfReactants>
3171 <speciesReference species="M_asp_L_e" stoichiometry="1.000000"/>
3172 <speciesReference species="M_h_e" stoichiometry="3.000000"/>
3173 </listOfReactants>
3174 <listOfProducts>
3175 <speciesReference species="M_asp_L_c" stoichiometry="1.000000"/>
3176 <speciesReference species="M_h_c" stoichiometry="3.000000"/>
3177 </listOfProducts>
3178 </reaction>
3179 <reaction id="R_AST" name="R_Arginine_succinyltransferase" reversible="false">
3180 <notes>
3181 <html:p>GENE_ASSOCIATION: b1747</html:p>
3182 <html:p>PROTEIN_ASSOCIATION: AstA</html:p>
3183 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
3184 <html:p>PROTEIN_CLASS: 2.3.1.109</html:p>
3185 </notes>
3186 <listOfReactants>
3187 <speciesReference species="M_arg_L_c" stoichiometry="1.000000"/>
3188 <speciesReference species="M_succoa_c" stoichiometry="1.000000"/>
3189 </listOfReactants>
3190 <listOfProducts>
3191 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
3192 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
3193 <speciesReference species="M_sucarg_c" stoichiometry="1.000000"/>
3194 </listOfProducts>
3195 </reaction>
3196 <reaction id="R_ATPM" name="R_ATP_maintenance_requirement" reversible="false">
3197 <notes>
3198 <html:p>GENE_ASSOCIATION: </html:p>
3199 <html:p>PROTEIN_ASSOCIATION: </html:p>
3200 <html:p>SUBSYSTEM: S_Unassigned</html:p>
3201 <html:p>PROTEIN_CLASS: </html:p>
3202 </notes>
3203 <listOfReactants>
3204 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
3205 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
3206 </listOfReactants>
3207 <listOfProducts>
3208 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
3209 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
3210 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
3211 </listOfProducts>
3212 </reaction>
3213 <reaction id="R_ATPPRT" name="R_ATP_phosphoribosyltransferase" reversible="false">
3214 <notes>
3215 <html:p>GENE_ASSOCIATION: b2019</html:p>
3216 <html:p>PROTEIN_ASSOCIATION: HisG</html:p>
3217 <html:p>SUBSYSTEM: S_Histidine_Metabolism</html:p>
3218 <html:p>PROTEIN_CLASS: 2.4.2.17</html:p>
3219 </notes>
3220 <listOfReactants>
3221 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
3222 <speciesReference species="M_prpp_c" stoichiometry="1.000000"/>
3223 </listOfReactants>
3224 <listOfProducts>
3225 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
3226 <speciesReference species="M_prbatp_c" stoichiometry="1.000000"/>
3227 </listOfProducts>
3228 </reaction>
3229 <reaction id="R_ATPS4r" name="R_ATP_synthase__four_protons_for_one_ATP_" reversible="true">
3230 <notes>
3231 <html:p>GENE_ASSOCIATION: ( ( b3736 and b3737 and b3738 ) and ( b3731 and b3732 and b3733 and b3734 and b3735 ) and b3739 )</html:p>
3232 <html:p>PROTEIN_ASSOCIATION: ( AtpF0 and AtpF1 and AtpI )</html:p>
3233 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
3234 <html:p>PROTEIN_CLASS: 3.6.3.14</html:p>
3235 </notes>
3236 <listOfReactants>
3237 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
3238 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
3239 <speciesReference species="M_h_e" stoichiometry="4.000000"/>
3240 </listOfReactants>
3241 <listOfProducts>
3242 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
3243 <speciesReference species="M_h_c" stoichiometry="3.000000"/>
3244 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
3245 </listOfProducts>
3246 </reaction>
3247 <reaction id="R_BETALDHx" name="R_betaine_aldehyde_dehydrogenase" reversible="false">
3248 <notes>
3249 <html:p>GENE_ASSOCIATION: b0312</html:p>
3250 <html:p>PROTEIN_ASSOCIATION: BetB</html:p>
3251 <html:p>SUBSYSTEM: S_Unassigned</html:p>
3252 <html:p>PROTEIN_CLASS: 1.2.1.8</html:p>
3253 </notes>
3254 <listOfReactants>
3255 <speciesReference species="M_betald_c" stoichiometry="1.000000"/>
3256 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
3257 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
3258 </listOfReactants>
3259 <listOfProducts>
3260 <speciesReference species="M_glyb_c" stoichiometry="1.000000"/>
3261 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
3262 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
3263 </listOfProducts>
3264 </reaction>
3265 <reaction id="R_BETALDHy" name="R_betaine_aldehyde_dehydrogenase" reversible="false">
3266 <notes>
3267 <html:p>GENE_ASSOCIATION: b0312</html:p>
3268 <html:p>PROTEIN_ASSOCIATION: BetB</html:p>
3269 <html:p>SUBSYSTEM: S_Unassigned</html:p>
3270 <html:p>PROTEIN_CLASS: 1.2.1.8</html:p>
3271 </notes>
3272 <listOfReactants>
3273 <speciesReference species="M_betald_c" stoichiometry="1.000000"/>
3274 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
3275 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
3276 </listOfReactants>
3277 <listOfProducts>
3278 <speciesReference species="M_glyb_c" stoichiometry="1.000000"/>
3279 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
3280 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
3281 </listOfProducts>
3282 </reaction>
3283 <reaction id="R_BPNT" name="R_3__5__bisphosphate_nucleotidase" reversible="false">
3284 <notes>
3285 <html:p>GENE_ASSOCIATION: </html:p>
3286 <html:p>PROTEIN_ASSOCIATION: </html:p>
3287 <html:p>SUBSYSTEM: S_Cysteine_Metabolism</html:p>
3288 <html:p>PROTEIN_CLASS: 3.1.3.7</html:p>
3289 </notes>
3290 <listOfReactants>
3291 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
3292 <speciesReference species="M_pap_c" stoichiometry="1.000000"/>
3293 </listOfReactants>
3294 <listOfProducts>
3295 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
3296 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
3297 </listOfProducts>
3298 </reaction>
3299 <reaction id="R_BSORx" name="R_Biotin_sulfoxide_reductase" reversible="false">
3300 <notes>
3301 <html:p>GENE_ASSOCIATION: b3551</html:p>
3302 <html:p>PROTEIN_ASSOCIATION: BisC</html:p>
3303 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
3304 <html:p>PROTEIN_CLASS: </html:p>
3305 </notes>
3306 <listOfReactants>
3307 <speciesReference species="M_btnso_c" stoichiometry="1.000000"/>
3308 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
3309 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
3310 </listOfReactants>
3311 <listOfProducts>
3312 <speciesReference species="M_btn_c" stoichiometry="1.000000"/>
3313 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
3314 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
3315 </listOfProducts>
3316 </reaction>
3317 <reaction id="R_BSORy" name="R_Biotin_sulfoxide_reductase" reversible="false">
3318 <notes>
3319 <html:p>GENE_ASSOCIATION: b3551</html:p>
3320 <html:p>PROTEIN_ASSOCIATION: BisC</html:p>
3321 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
3322 <html:p>PROTEIN_CLASS: </html:p>
3323 </notes>
3324 <listOfReactants>
3325 <speciesReference species="M_btnso_c" stoichiometry="1.000000"/>
3326 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
3327 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
3328 </listOfReactants>
3329 <listOfProducts>
3330 <speciesReference species="M_btn_c" stoichiometry="1.000000"/>
3331 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
3332 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
3333 </listOfProducts>
3334 </reaction>
3335 <reaction id="R_BTS2" name="R_biotin_synthase__ala_L_producing_" reversible="true">
3336 <notes>
3337 <html:p>GENE_ASSOCIATION: b0775</html:p>
3338 <html:p>PROTEIN_ASSOCIATION: BioBec</html:p>
3339 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
3340 <html:p>PROTEIN_CLASS: </html:p>
3341 </notes>
3342 <listOfReactants>
3343 <speciesReference species="M_cys_L_c" stoichiometry="1.000000"/>
3344 <speciesReference species="M_dtbt_c" stoichiometry="1.000000"/>
3345 </listOfReactants>
3346 <listOfProducts>
3347 <speciesReference species="M_ala_L_c" stoichiometry="1.000000"/>
3348 <speciesReference species="M_btn_c" stoichiometry="1.000000"/>
3349 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
3350 </listOfProducts>
3351 </reaction>
3352 <reaction id="R_BUTCT" name="R_Acetyl_CoAbutyrate_CoA_transferase" reversible="false">
3353 <notes>
3354 <html:p>GENE_ASSOCIATION: ( b2221 and b2222 )</html:p>
3355 <html:p>PROTEIN_ASSOCIATION: AtoADec</html:p>
3356 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
3357 <html:p>PROTEIN_CLASS: 2.8.3.8</html:p>
3358 </notes>
3359 <listOfReactants>
3360 <speciesReference species="M_accoa_c" stoichiometry="1.000000"/>
3361 <speciesReference species="M_but_c" stoichiometry="1.000000"/>
3362 </listOfReactants>
3363 <listOfProducts>
3364 <speciesReference species="M_ac_c" stoichiometry="1.000000"/>
3365 <speciesReference species="M_btcoa_c" stoichiometry="1.000000"/>
3366 </listOfProducts>
3367 </reaction>
3368 <reaction id="R_BUTt2r" name="R_Butyrate_transport_via_proton_symport__reversible" reversible="true">
3369 <notes>
3370 <html:p>GENE_ASSOCIATION: b2223</html:p>
3371 <html:p>PROTEIN_ASSOCIATION: AtoE</html:p>
3372 <html:p>SUBSYSTEM: S_Putative_Transporters</html:p>
3373 <html:p>PROTEIN_CLASS: </html:p>
3374 </notes>
3375 <listOfReactants>
3376 <speciesReference species="M_but_e" stoichiometry="1.000000"/>
3377 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
3378 </listOfReactants>
3379 <listOfProducts>
3380 <speciesReference species="M_but_c" stoichiometry="1.000000"/>
3381 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
3382 </listOfProducts>
3383 </reaction>
3384 <reaction id="R_BiomassEcoli" name="R_BiomassEcoli" reversible="false">
3385 <notes>
3386 <html:p>GENE_ASSOCIATION: </html:p>
3387 <html:p>PROTEIN_ASSOCIATION: </html:p>
3388 <html:p>SUBSYSTEM: </html:p>
3389 <html:p>PROTEIN_CLASS: </html:p>
3390 </notes>
3391 <listOfReactants>
3392 <speciesReference species="M_5mthf_c" stoichiometry="0.050000"/>
3393 <speciesReference species="M_accoa_c" stoichiometry="0.000050"/>
3394 <speciesReference species="M_ala_L_c" stoichiometry="0.488000"/>
3395 <speciesReference species="M_amp_c" stoichiometry="0.001000"/>
3396 <speciesReference species="M_arg_L_c" stoichiometry="0.281000"/>
3397 <speciesReference species="M_asn_L_c" stoichiometry="0.229000"/>
3398 <speciesReference species="M_asp_L_c" stoichiometry="0.229000"/>
3399 <speciesReference species="M_atp_c" stoichiometry="45.731800"/>
3400 <speciesReference species="M_clpn_EC_c" stoichiometry="0.000129"/>
3401 <speciesReference species="M_coa_c" stoichiometry="0.000006"/>
3402 <speciesReference species="M_ctp_c" stoichiometry="0.126000"/>
3403 <speciesReference species="M_cys_L_c" stoichiometry="0.087000"/>
3404 <speciesReference species="M_datp_c" stoichiometry="0.024700"/>
3405 <speciesReference species="M_dctp_c" stoichiometry="0.025400"/>
3406 <speciesReference species="M_dgtp_c" stoichiometry="0.025400"/>
3407 <speciesReference species="M_dttp_c" stoichiometry="0.024700"/>
3408 <speciesReference species="M_fad_c" stoichiometry="0.000010"/>
3409 <speciesReference species="M_gln_L_c" stoichiometry="0.250000"/>
3410 <speciesReference species="M_glu_L_c" stoichiometry="0.250000"/>
3411 <speciesReference species="M_gly_c" stoichiometry="0.582000"/>
3412 <speciesReference species="M_glycogen_c" stoichiometry="0.154000"/>
3413 <speciesReference species="M_gtp_c" stoichiometry="0.203000"/>
3414 <speciesReference species="M_h2o_c" stoichiometry="45.560800"/>
3415 <speciesReference species="M_his_L_c" stoichiometry="0.090000"/>
3416 <speciesReference species="M_ile_L_c" stoichiometry="0.276000"/>
3417 <speciesReference species="M_leu_L_c" stoichiometry="0.428000"/>
3418 <speciesReference species="M_lps_EC_c" stoichiometry="0.008400"/>
3419 <speciesReference species="M_lys_L_c" stoichiometry="0.326000"/>
3420 <speciesReference species="M_met_L_c" stoichiometry="0.146000"/>
3421 <speciesReference species="M_nad_c" stoichiometry="0.002150"/>
3422 <speciesReference species="M_nadh_c" stoichiometry="0.000050"/>
3423 <speciesReference species="M_nadp_c" stoichiometry="0.000130"/>
3424 <speciesReference species="M_nadph_c" stoichiometry="0.000400"/>
3425 <speciesReference species="M_pe_EC_c" stoichiometry="0.001935"/>
3426 <speciesReference species="M_peptido_EC_c" stoichiometry="0.027600"/>
3427 <speciesReference species="M_pg_EC_c" stoichiometry="0.000464"/>
3428 <speciesReference species="M_phe_L_c" stoichiometry="0.176000"/>
3429 <speciesReference species="M_pro_L_c" stoichiometry="0.210000"/>
3430 <speciesReference species="M_ps_EC_c" stoichiometry="0.000052"/>
3431 <speciesReference species="M_ptrc_c" stoichiometry="0.035000"/>
3432 <speciesReference species="M_ser_L_c" stoichiometry="0.205000"/>
3433 <speciesReference species="M_spmd_c" stoichiometry="0.007000"/>
3434 <speciesReference species="M_succoa_c" stoichiometry="0.000003"/>
3435 <speciesReference species="M_thr_L_c" stoichiometry="0.241000"/>
3436 <speciesReference species="M_trp_L_c" stoichiometry="0.054000"/>
3437 <speciesReference species="M_tyr_L_c" stoichiometry="0.131000"/>
3438 <speciesReference species="M_udpg_c" stoichiometry="0.003000"/>
3439 <speciesReference species="M_utp_c" stoichiometry="0.136000"/>
3440 <speciesReference species="M_val_L_c" stoichiometry="0.402000"/>
3441 </listOfReactants>
3442 <listOfProducts>
3443 <speciesReference species="M_adp_c" stoichiometry="45.560800"/>
3444 <speciesReference species="M_h_c" stoichiometry="45.560350"/>
3445 <speciesReference species="M_pi_c" stoichiometry="45.562800"/>
3446 <speciesReference species="M_ppi_c" stoichiometry="0.730200"/>
3447 </listOfProducts>
3448 </reaction>
3449 <reaction id="R_C120SN" name="R_Fatty_acid_biosynthesis__n_C120_" reversible="false">
3450 <notes>
3451 <html:p>GENE_ASSOCIATION: ( ( b0954 and b2323 and b1093 and b1288 ) or ( b2323 and b1093 and b1288 and b0180 ) or ( b1095 and b1093 and b1288 and b0180 ) or ( b0954 and b1095 and b1093 and b1288 ) )</html:p>
3452 <html:p>PROTEIN_ASSOCIATION: ( FabA and FabB and FabGec and FabI ) or ( FabB and FabGec and FabI and FabZ ) or ( FabF and FabGec and FabI and FabZ ) or ( FabA and FabF and FabGec and FabI )</html:p>
3453 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
3454 <html:p>PROTEIN_CLASS: </html:p>
3455 </notes>
3456 <listOfReactants>
3457 <speciesReference species="M_actACP_c" stoichiometry="1.000000"/>
3458 <speciesReference species="M_h_c" stoichiometry="14.000000"/>
3459 <speciesReference species="M_malACP_c" stoichiometry="4.000000"/>
3460 <speciesReference species="M_nadph_c" stoichiometry="10.000000"/>
3461 </listOfReactants>
3462 <listOfProducts>
3463 <speciesReference species="M_ACP_c" stoichiometry="4.000000"/>
3464 <speciesReference species="M_co2_c" stoichiometry="4.000000"/>
3465 <speciesReference species="M_ddcaACP_c" stoichiometry="1.000000"/>
3466 <speciesReference species="M_h2o_c" stoichiometry="5.000000"/>
3467 <speciesReference species="M_nadp_c" stoichiometry="10.000000"/>
3468 </listOfProducts>
3469 </reaction>
3470 <reaction id="R_C140SN" name="R_Fatty_acid_biosynthesis__n_C140_" reversible="false">
3471 <notes>
3472 <html:p>GENE_ASSOCIATION: ( ( b0954 and b2323 and b1093 and b1288 ) or ( b2323 and b1093 and b1288 and b0180 ) or ( b1095 and b1093 and b1288 and b0180 ) or ( b0954 and b1095 and b1093 and b1288 ) )</html:p>
3473 <html:p>PROTEIN_ASSOCIATION: ( FabA and FabB and FabGec and FabI ) or ( FabB and FabGec and FabI and FabZ ) or ( FabF and FabGec and FabI and FabZ ) or ( FabA and FabF and FabGec and FabI )</html:p>
3474 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
3475 <html:p>PROTEIN_CLASS: </html:p>
3476 </notes>
3477 <listOfReactants>
3478 <speciesReference species="M_actACP_c" stoichiometry="1.000000"/>
3479 <speciesReference species="M_h_c" stoichiometry="17.000000"/>
3480 <speciesReference species="M_malACP_c" stoichiometry="5.000000"/>
3481 <speciesReference species="M_nadph_c" stoichiometry="12.000000"/>
3482 </listOfReactants>
3483 <listOfProducts>
3484 <speciesReference species="M_ACP_c" stoichiometry="5.000000"/>
3485 <speciesReference species="M_co2_c" stoichiometry="5.000000"/>
3486 <speciesReference species="M_h2o_c" stoichiometry="6.000000"/>
3487 <speciesReference species="M_myrsACP_c" stoichiometry="1.000000"/>
3488 <speciesReference species="M_nadp_c" stoichiometry="12.000000"/>
3489 </listOfProducts>
3490 </reaction>
3491 <reaction id="R_C141SN" name="R_Fatty_acid_biosynthesis__n_C141_" reversible="false">
3492 <notes>
3493 <html:p>GENE_ASSOCIATION: ( b0954 and b2323 and b1093 and b1288 and b0180 )</html:p>
3494 <html:p>PROTEIN_ASSOCIATION: ( FabA and FabB and FabGec and FabI and FabZ )</html:p>
3495 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
3496 <html:p>PROTEIN_CLASS: </html:p>
3497 </notes>
3498 <listOfReactants>
3499 <speciesReference species="M_actACP_c" stoichiometry="1.000000"/>
3500 <speciesReference species="M_h_c" stoichiometry="16.000000"/>
3501 <speciesReference species="M_malACP_c" stoichiometry="5.000000"/>
3502 <speciesReference species="M_nadph_c" stoichiometry="11.000000"/>
3503 </listOfReactants>
3504 <listOfProducts>
3505 <speciesReference species="M_ACP_c" stoichiometry="5.000000"/>
3506 <speciesReference species="M_co2_c" stoichiometry="5.000000"/>
3507 <speciesReference species="M_h2o_c" stoichiometry="6.000000"/>
3508 <speciesReference species="M_nadp_c" stoichiometry="11.000000"/>
3509 <speciesReference species="M_tdeACP_c" stoichiometry="1.000000"/>
3510 </listOfProducts>
3511 </reaction>
3512 <reaction id="R_C160SN" name="R_Fatty_acid_biosynthesis__n_C160_" reversible="false">
3513 <notes>
3514 <html:p>GENE_ASSOCIATION: ( ( b0954 and b2323 and b1093 and b1288 ) or ( b2323 and b1093 and b1288 and b0180 ) or ( b1095 and b1093 and b1288 and b0180 ) or ( b0954 and b1095 and b1093 and b1288 ) )</html:p>
3515 <html:p>PROTEIN_ASSOCIATION: ( FabA and FabB and FabGec and FabI ) or ( FabB and FabGec and FabI and FabZ ) or ( FabF and FabGec and FabI and FabZ ) or ( FabA and FabF and FabGec and FabI )</html:p>
3516 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
3517 <html:p>PROTEIN_CLASS: </html:p>
3518 </notes>
3519 <listOfReactants>
3520 <speciesReference species="M_actACP_c" stoichiometry="1.000000"/>
3521 <speciesReference species="M_h_c" stoichiometry="20.000000"/>
3522 <speciesReference species="M_malACP_c" stoichiometry="6.000000"/>
3523 <speciesReference species="M_nadph_c" stoichiometry="14.000000"/>
3524 </listOfReactants>
3525 <listOfProducts>
3526 <speciesReference species="M_ACP_c" stoichiometry="6.000000"/>
3527 <speciesReference species="M_co2_c" stoichiometry="6.000000"/>
3528 <speciesReference species="M_h2o_c" stoichiometry="7.000000"/>
3529 <speciesReference species="M_nadp_c" stoichiometry="14.000000"/>
3530 <speciesReference species="M_palmACP_c" stoichiometry="1.000000"/>
3531 </listOfProducts>
3532 </reaction>
3533 <reaction id="R_C161SN" name="R_Fatty_acid_biosynthesis__n_C161_" reversible="false">
3534 <notes>
3535 <html:p>GENE_ASSOCIATION: ( b0954 and b2323 and b1093 and b1288 and b0180 )</html:p>
3536 <html:p>PROTEIN_ASSOCIATION: ( FabA and FabB and FabGec and FabI and FabZ )</html:p>
3537 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
3538 <html:p>PROTEIN_CLASS: </html:p>
3539 </notes>
3540 <listOfReactants>
3541 <speciesReference species="M_actACP_c" stoichiometry="1.000000"/>
3542 <speciesReference species="M_h_c" stoichiometry="19.000000"/>
3543 <speciesReference species="M_malACP_c" stoichiometry="6.000000"/>
3544 <speciesReference species="M_nadph_c" stoichiometry="13.000000"/>
3545 </listOfReactants>
3546 <listOfProducts>
3547 <speciesReference species="M_ACP_c" stoichiometry="6.000000"/>
3548 <speciesReference species="M_co2_c" stoichiometry="6.000000"/>
3549 <speciesReference species="M_h2o_c" stoichiometry="7.000000"/>
3550 <speciesReference species="M_hdeACP_c" stoichiometry="1.000000"/>
3551 <speciesReference species="M_nadp_c" stoichiometry="13.000000"/>
3552 </listOfProducts>
3553 </reaction>
3554 <reaction id="R_C181SN" name="R_Fatty_acid_biosynthesis__n_C181_" reversible="false">
3555 <notes>
3556 <html:p>GENE_ASSOCIATION: ( b0954 and b2323 and b1095 and b1093 and b1288 and b0180 )</html:p>
3557 <html:p>PROTEIN_ASSOCIATION: ( FabA and FabB and FabF and FabGec and FabI and FabZ )</html:p>
3558 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
3559 <html:p>PROTEIN_CLASS: </html:p>
3560 </notes>
3561 <listOfReactants>
3562 <speciesReference species="M_actACP_c" stoichiometry="1.000000"/>
3563 <speciesReference species="M_h_c" stoichiometry="22.000000"/>
3564 <speciesReference species="M_malACP_c" stoichiometry="7.000000"/>
3565 <speciesReference species="M_nadph_c" stoichiometry="15.000000"/>
3566 </listOfReactants>
3567 <listOfProducts>
3568 <speciesReference species="M_ACP_c" stoichiometry="7.000000"/>
3569 <speciesReference species="M_co2_c" stoichiometry="7.000000"/>
3570 <speciesReference species="M_h2o_c" stoichiometry="8.000000"/>
3571 <speciesReference species="M_nadp_c" stoichiometry="15.000000"/>
3572 <speciesReference species="M_octeACP_c" stoichiometry="1.000000"/>
3573 </listOfProducts>
3574 </reaction>
3575 <reaction id="R_CADVt" name="R_LysineCadaverine_antiporter" reversible="false">
3576 <notes>
3577 <html:p>GENE_ASSOCIATION: b4132</html:p>
3578 <html:p>PROTEIN_ASSOCIATION: CadB</html:p>
3579 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
3580 <html:p>PROTEIN_CLASS: </html:p>
3581 </notes>
3582 <listOfReactants>
3583 <speciesReference species="M_15dap_c" stoichiometry="1.000000"/>
3584 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
3585 <speciesReference species="M_lys_L_e" stoichiometry="1.000000"/>
3586 </listOfReactants>
3587 <listOfProducts>
3588 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
3589 <speciesReference species="M_lys_L_c" stoichiometry="1.000000"/>
3590 <speciesReference species="M_15dap_e" stoichiometry="1.000000"/>
3591 </listOfProducts>
3592 </reaction>
3593 <reaction id="R_CAT" name="R_catalase" reversible="false">
3594 <notes>
3595 <html:p>GENE_ASSOCIATION: ( b1732 or b3942 )</html:p>
3596 <html:p>PROTEIN_ASSOCIATION: ( KatE ) or ( KatG )</html:p>
3597 <html:p>SUBSYSTEM: S_Unassigned</html:p>
3598 <html:p>PROTEIN_CLASS: 1.11.1.6</html:p>
3599 </notes>
3600 <listOfReactants>
3601 <speciesReference species="M_h2o2_c" stoichiometry="2.000000"/>
3602 </listOfReactants>
3603 <listOfProducts>
3604 <speciesReference species="M_h2o_c" stoichiometry="2.000000"/>
3605 <speciesReference species="M_o2_c" stoichiometry="1.000000"/>
3606 </listOfProducts>
3607 </reaction>
3608 <reaction id="R_CBIAT_DELETE" name="R_Cobinamide_adenyltransferase" reversible="true">
3609 <notes>
3610 <html:p>GENE_ASSOCIATION: b1270</html:p>
3611 <html:p>PROTEIN_ASSOCIATION: BtuR</html:p>
3612 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
3613 <html:p>PROTEIN_CLASS: </html:p>
3614 </notes>
3615 <listOfReactants>
3616 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
3617 <speciesReference species="M_cbi_c" stoichiometry="1.000000"/>
3618 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
3619 </listOfReactants>
3620 <listOfProducts>
3621 <speciesReference species="M_adocbi_c" stoichiometry="1.000000"/>
3622 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
3623 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
3624 </listOfProducts>
3625 </reaction>
3626 <reaction id="R_CBL1abc" name="R_Cob_1_alamin_transport_via_ABC_system" reversible="false">
3627 <notes>
3628 <html:p>GENE_ASSOCIATION: ( b3966 and b1711 and b1709 and b0158 )</html:p>
3629 <html:p>PROTEIN_ASSOCIATION: ( BtuB and BtuC and BtuD and BtuF )</html:p>
3630 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
3631 <html:p>PROTEIN_CLASS: </html:p>
3632 </notes>
3633 <listOfReactants>
3634 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
3635 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
3636 <speciesReference species="M_cbl1_e" stoichiometry="1.000000"/>
3637 </listOfReactants>
3638 <listOfProducts>
3639 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
3640 <speciesReference species="M_cbl1_c" stoichiometry="1.000000"/>
3641 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
3642 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
3643 </listOfProducts>
3644 </reaction>
3645 <reaction id="R_CBLAT_DELETE" name="R_cob_I_alamin_adenosyltransferase" reversible="true">
3646 <notes>
3647 <html:p>GENE_ASSOCIATION: b1270</html:p>
3648 <html:p>PROTEIN_ASSOCIATION: BtuR</html:p>
3649 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
3650 <html:p>PROTEIN_CLASS: 2.5.1.17</html:p>
3651 </notes>
3652 <listOfReactants>
3653 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
3654 <speciesReference species="M_cbl1_c" stoichiometry="1.000000"/>
3655 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
3656 </listOfReactants>
3657 <listOfProducts>
3658 <speciesReference species="M_adocbl_c" stoichiometry="1.000000"/>
3659 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
3660 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
3661 </listOfProducts>
3662 </reaction>
3663 <reaction id="R_CBMK" name="R_Carbamate_kinase" reversible="false">
3664 <notes>
3665 <html:p>GENE_ASSOCIATION: ( b0521 or b2874 or b0323 )</html:p>
3666 <html:p>PROTEIN_ASSOCIATION: ( ArcCec ) or ( YqeA ) or ( YahI )</html:p>
3667 <html:p>SUBSYSTEM: S_Putative</html:p>
3668 <html:p>PROTEIN_CLASS: 2.7.2.2</html:p>
3669 </notes>
3670 <listOfReactants>
3671 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
3672 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
3673 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
3674 </listOfReactants>
3675 <listOfProducts>
3676 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
3677 <speciesReference species="M_cbp_c" stoichiometry="1.000000"/>
3678 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
3679 </listOfProducts>
3680 </reaction>
3681 <reaction id="R_CBPS" name="R_carbamoyl_phosphate_synthase__glutamine_hydrolysing_" reversible="false">
3682 <notes>
3683 <html:p>GENE_ASSOCIATION: ( b0032 and b0033 )</html:p>
3684 <html:p>PROTEIN_ASSOCIATION: Car</html:p>
3685 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
3686 <html:p>PROTEIN_CLASS: 6.3.5.5</html:p>
3687 </notes>
3688 <listOfReactants>
3689 <speciesReference species="M_atp_c" stoichiometry="2.000000"/>
3690 <speciesReference species="M_gln_L_c" stoichiometry="1.000000"/>
3691 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
3692 <speciesReference species="M_hco3_c" stoichiometry="1.000000"/>
3693 </listOfReactants>
3694 <listOfProducts>
3695 <speciesReference species="M_adp_c" stoichiometry="2.000000"/>
3696 <speciesReference species="M_cbp_c" stoichiometry="1.000000"/>
3697 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
3698 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
3699 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
3700 </listOfProducts>
3701 </reaction>
3702 <reaction id="R_CDAPPA_EC" name="R_CDP_Diacylglycerol_pyrophostatase__Ecoli_" reversible="false">
3703 <notes>
3704 <html:p>GENE_ASSOCIATION: b3918</html:p>
3705 <html:p>PROTEIN_ASSOCIATION: Cdhec</html:p>
3706 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
3707 <html:p>PROTEIN_CLASS: 3.6.1.26</html:p>
3708 </notes>
3709 <listOfReactants>
3710 <speciesReference species="M_cdpdag_EC_c" stoichiometry="0.020000"/>
3711 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
3712 </listOfReactants>
3713 <listOfProducts>
3714 <speciesReference species="M_cmp_c" stoichiometry="1.000000"/>
3715 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
3716 <speciesReference species="M_pa_EC_c" stoichiometry="0.020000"/>
3717 </listOfProducts>
3718 </reaction>
3719 <reaction id="R_CDPMEK" name="R_4__cytidine_5__diphospho__2_C_methyl_D_erythritol_kinase" reversible="false">
3720 <notes>
3721 <html:p>GENE_ASSOCIATION: b1208</html:p>
3722 <html:p>PROTEIN_ASSOCIATION: IspE</html:p>
3723 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
3724 <html:p>PROTEIN_CLASS: </html:p>
3725 </notes>
3726 <listOfReactants>
3727 <speciesReference species="M_4c2me_c" stoichiometry="1.000000"/>
3728 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
3729 </listOfReactants>
3730 <listOfProducts>
3731 <speciesReference species="M_2p4c2me_c" stoichiometry="1.000000"/>
3732 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
3733 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
3734 </listOfProducts>
3735 </reaction>
3736 <reaction id="R_CHLabc" name="R_choline_transport_via_ABC_system" reversible="false">
3737 <notes>
3738 <html:p>GENE_ASSOCIATION: ( b2128 and b2129 and b2130 and b2131 )</html:p>
3739 <html:p>PROTEIN_ASSOCIATION: ( YehW and YehX and YehY and YehZ )</html:p>
3740 <html:p>SUBSYSTEM: S_Putative_Transporters</html:p>
3741 <html:p>PROTEIN_CLASS: </html:p>
3742 </notes>
3743 <listOfReactants>
3744 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
3745 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
3746 <speciesReference species="M_chol_e" stoichiometry="1.000000"/>
3747 </listOfReactants>
3748 <listOfProducts>
3749 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
3750 <speciesReference species="M_chol_c" stoichiometry="1.000000"/>
3751 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
3752 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
3753 </listOfProducts>
3754 </reaction>
3755 <reaction id="R_CHLt2r" name="R_choline_transport_via_proton_symport__reversible" reversible="true">
3756 <notes>
3757 <html:p>GENE_ASSOCIATION: ( b0314 or b1801 )</html:p>
3758 <html:p>PROTEIN_ASSOCIATION: ( BetT ) or ( YeaV )</html:p>
3759 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
3760 <html:p>PROTEIN_CLASS: </html:p>
3761 </notes>
3762 <listOfReactants>
3763 <speciesReference species="M_chol_e" stoichiometry="1.000000"/>
3764 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
3765 </listOfReactants>
3766 <listOfProducts>
3767 <speciesReference species="M_chol_c" stoichiometry="1.000000"/>
3768 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
3769 </listOfProducts>
3770 </reaction>
3771 <reaction id="R_CHORM" name="R_chorismate_mutase" reversible="false">
3772 <notes>
3773 <html:p>GENE_ASSOCIATION: ( b2599 or b2600 )</html:p>
3774 <html:p>PROTEIN_ASSOCIATION: ( PheA ) or ( TyrAec )</html:p>
3775 <html:p>SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism</html:p>
3776 <html:p>PROTEIN_CLASS: 5.4.99.5</html:p>
3777 </notes>
3778 <listOfReactants>
3779 <speciesReference species="M_chor_c" stoichiometry="1.000000"/>
3780 </listOfReactants>
3781 <listOfProducts>
3782 <speciesReference species="M_pphn_c" stoichiometry="1.000000"/>
3783 </listOfProducts>
3784 </reaction>
3785 <reaction id="R_CHORS" name="R_chorismate_synthase" reversible="false">
3786 <notes>
3787 <html:p>GENE_ASSOCIATION: b2329</html:p>
3788 <html:p>PROTEIN_ASSOCIATION: AroC</html:p>
3789 <html:p>SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism</html:p>
3790 <html:p>PROTEIN_CLASS: 4.2.3.5</html:p>
3791 </notes>
3792 <listOfReactants>
3793 <speciesReference species="M_3psme_c" stoichiometry="1.000000"/>
3794 </listOfReactants>
3795 <listOfProducts>
3796 <speciesReference species="M_chor_c" stoichiometry="1.000000"/>
3797 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
3798 </listOfProducts>
3799 </reaction>
3800 <reaction id="R_CHRPL" name="R_Chorismate_pyruvate_lyase" reversible="false">
3801 <notes>
3802 <html:p>GENE_ASSOCIATION: b4039</html:p>
3803 <html:p>PROTEIN_ASSOCIATION: UbiC</html:p>
3804 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
3805 <html:p>PROTEIN_CLASS: </html:p>
3806 </notes>
3807 <listOfReactants>
3808 <speciesReference species="M_chor_c" stoichiometry="1.000000"/>
3809 </listOfReactants>
3810 <listOfProducts>
3811 <speciesReference species="M_4hbz_c" stoichiometry="1.000000"/>
3812 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
3813 </listOfProducts>
3814 </reaction>
3815 <reaction id="R_CINNDO" name="R_Cinnamate_dioxygenase" reversible="false">
3816 <notes>
3817 <html:p>GENE_ASSOCIATION: ( b2538 and b2539 and b2540 and b2542 )</html:p>
3818 <html:p>PROTEIN_ASSOCIATION: HcaCDEF</html:p>
3819 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
3820 <html:p>PROTEIN_CLASS: </html:p>
3821 </notes>
3822 <listOfReactants>
3823 <speciesReference species="M_cinnm_c" stoichiometry="1.000000"/>
3824 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
3825 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
3826 <speciesReference species="M_o2_c" stoichiometry="1.000000"/>
3827 </listOfReactants>
3828 <listOfProducts>
3829 <speciesReference species="M_cenchddd_c" stoichiometry="1.000000"/>
3830 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
3831 </listOfProducts>
3832 </reaction>
3833 <reaction id="R_CITL" name="R_Citrate_lyase" reversible="false">
3834 <notes>
3835 <html:p>GENE_ASSOCIATION: ( b0615 and b0616 and b0617 )</html:p>
3836 <html:p>PROTEIN_ASSOCIATION: CitDEF</html:p>
3837 <html:p>SUBSYSTEM: S_Citric_Acid_Cycle</html:p>
3838 <html:p>PROTEIN_CLASS: 4.1.3.6</html:p>
3839 </notes>
3840 <listOfReactants>
3841 <speciesReference species="M_cit_c" stoichiometry="1.000000"/>
3842 </listOfReactants>
3843 <listOfProducts>
3844 <speciesReference species="M_ac_c" stoichiometry="1.000000"/>
3845 <speciesReference species="M_oaa_c" stoichiometry="1.000000"/>
3846 </listOfProducts>
3847 </reaction>
3848 <reaction id="R_CITt7" name="R_Citrate_transport_via_succinate_antiport" reversible="false">
3849 <notes>
3850 <html:p>GENE_ASSOCIATION: b0612</html:p>
3851 <html:p>PROTEIN_ASSOCIATION: CitT</html:p>
3852 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
3853 <html:p>PROTEIN_CLASS: </html:p>
3854 </notes>
3855 <listOfReactants>
3856 <speciesReference species="M_succ_c" stoichiometry="1.000000"/>
3857 <speciesReference species="M_cit_e" stoichiometry="1.000000"/>
3858 </listOfReactants>
3859 <listOfProducts>
3860 <speciesReference species="M_cit_c" stoichiometry="1.000000"/>
3861 <speciesReference species="M_succ_e" stoichiometry="1.000000"/>
3862 </listOfProducts>
3863 </reaction>
3864 <reaction id="R_CLPNS_EC" name="R_Cardiolipin_Synthase__Ecoli_" reversible="true">
3865 <notes>
3866 <html:p>GENE_ASSOCIATION: b1249</html:p>
3867 <html:p>PROTEIN_ASSOCIATION: Cls</html:p>
3868 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
3869 <html:p>PROTEIN_CLASS: </html:p>
3870 </notes>
3871 <listOfReactants>
3872 <speciesReference species="M_pg_EC_c" stoichiometry="0.040000"/>
3873 </listOfReactants>
3874 <listOfProducts>
3875 <speciesReference species="M_clpn_EC_c" stoichiometry="0.020000"/>
3876 <speciesReference species="M_glyc_c" stoichiometry="1.000000"/>
3877 </listOfProducts>
3878 </reaction>
3879 <reaction id="R_CMPN" name="R_CMP_nucleosidase" reversible="false">
3880 <notes>
3881 <html:p>GENE_ASSOCIATION: </html:p>
3882 <html:p>PROTEIN_ASSOCIATION: </html:p>
3883 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
3884 <html:p>PROTEIN_CLASS: 3.2.2.10</html:p>
3885 </notes>
3886 <listOfReactants>
3887 <speciesReference species="M_cmp_c" stoichiometry="1.000000"/>
3888 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
3889 </listOfReactants>
3890 <listOfProducts>
3891 <speciesReference species="M_csn_c" stoichiometry="1.000000"/>
3892 <speciesReference species="M_r5p_c" stoichiometry="1.000000"/>
3893 </listOfProducts>
3894 </reaction>
3895 <reaction id="R_CO2t" name="R_CO2_transporter_via_diffusion" reversible="true">
3896 <notes>
3897 <html:p>GENE_ASSOCIATION: </html:p>
3898 <html:p>PROTEIN_ASSOCIATION: </html:p>
3899 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
3900 <html:p>PROTEIN_CLASS: </html:p>
3901 </notes>
3902 <listOfReactants>
3903 <speciesReference species="M_co2_e" stoichiometry="1.000000"/>
3904 </listOfReactants>
3905 <listOfProducts>
3906 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
3907 </listOfProducts>
3908 </reaction>
3909 <reaction id="R_CPPPGO" name="R_coproporphyrinogen_oxidase__O2_required_" reversible="false">
3910 <notes>
3911 <html:p>GENE_ASSOCIATION: b2436</html:p>
3912 <html:p>PROTEIN_ASSOCIATION: HemF</html:p>
3913 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
3914 <html:p>PROTEIN_CLASS: 1.3.3.3</html:p>
3915 </notes>
3916 <listOfReactants>
3917 <speciesReference species="M_cpppg3_c" stoichiometry="1.000000"/>
3918 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
3919 <speciesReference species="M_o2_c" stoichiometry="1.000000"/>
3920 </listOfReactants>
3921 <listOfProducts>
3922 <speciesReference species="M_co2_c" stoichiometry="2.000000"/>
3923 <speciesReference species="M_h2o_c" stoichiometry="2.000000"/>
3924 <speciesReference species="M_pppg9_c" stoichiometry="1.000000"/>
3925 </listOfProducts>
3926 </reaction>
3927 <reaction id="R_CRNBTCT" name="R_gamma_butyrobetainyl_CoA_carnitine_CoA_transferase" reversible="true">
3928 <notes>
3929 <html:p>GENE_ASSOCIATION: b0038</html:p>
3930 <html:p>PROTEIN_ASSOCIATION: CaiB</html:p>
3931 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
3932 <html:p>PROTEIN_CLASS: </html:p>
3933 </notes>
3934 <listOfReactants>
3935 <speciesReference species="M_bbtcoa_c" stoichiometry="1.000000"/>
3936 <speciesReference species="M_crn_c" stoichiometry="1.000000"/>
3937 </listOfReactants>
3938 <listOfProducts>
3939 <speciesReference species="M_crncoa_c" stoichiometry="1.000000"/>
3940 <speciesReference species="M_gbbtn_c" stoichiometry="1.000000"/>
3941 </listOfProducts>
3942 </reaction>
3943 <reaction id="R_CRNCBCT" name="R_crotonobetainyl_CoA_carnitine_CoA_transferase" reversible="true">
3944 <notes>
3945 <html:p>GENE_ASSOCIATION: b0038</html:p>
3946 <html:p>PROTEIN_ASSOCIATION: CaiB</html:p>
3947 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
3948 <html:p>PROTEIN_CLASS: </html:p>
3949 </notes>
3950 <listOfReactants>
3951 <speciesReference species="M_crn_c" stoichiometry="1.000000"/>
3952 <speciesReference species="M_ctbtcoa_c" stoichiometry="1.000000"/>
3953 </listOfReactants>
3954 <listOfProducts>
3955 <speciesReference species="M_crncoa_c" stoichiometry="1.000000"/>
3956 <speciesReference species="M_ctbt_c" stoichiometry="1.000000"/>
3957 </listOfProducts>
3958 </reaction>
3959 <reaction id="R_CRNCDH" name="R_Carnityl_CoA_dehydratse" reversible="true">
3960 <notes>
3961 <html:p>GENE_ASSOCIATION: b0036</html:p>
3962 <html:p>PROTEIN_ASSOCIATION: CaiD</html:p>
3963 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
3964 <html:p>PROTEIN_CLASS: </html:p>
3965 </notes>
3966 <listOfReactants>
3967 <speciesReference species="M_crncoa_c" stoichiometry="1.000000"/>
3968 </listOfReactants>
3969 <listOfProducts>
3970 <speciesReference species="M_ctbtcoa_c" stoichiometry="1.000000"/>
3971 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
3972 </listOfProducts>
3973 </reaction>
3974 <reaction id="R_CRNt7" name="R_Carnitinebutyrobetaine_antiporter" reversible="false">
3975 <notes>
3976 <html:p>GENE_ASSOCIATION: b0040</html:p>
3977 <html:p>PROTEIN_ASSOCIATION: CaiT</html:p>
3978 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
3979 <html:p>PROTEIN_CLASS: </html:p>
3980 </notes>
3981 <listOfReactants>
3982 <speciesReference species="M_gbbtn_c" stoichiometry="1.000000"/>
3983 <speciesReference species="M_crn_e" stoichiometry="1.000000"/>
3984 </listOfReactants>
3985 <listOfProducts>
3986 <speciesReference species="M_crn_c" stoichiometry="1.000000"/>
3987 <speciesReference species="M_gbbtn_e" stoichiometry="1.000000"/>
3988 </listOfProducts>
3989 </reaction>
3990 <reaction id="R_CS" name="R_citrate_synthase" reversible="false">
3991 <notes>
3992 <html:p>GENE_ASSOCIATION: b0720</html:p>
3993 <html:p>PROTEIN_ASSOCIATION: GltA</html:p>
3994 <html:p>SUBSYSTEM: S_Citric_Acid_Cycle</html:p>
3995 <html:p>PROTEIN_CLASS: </html:p>
3996 </notes>
3997 <listOfReactants>
3998 <speciesReference species="M_accoa_c" stoichiometry="1.000000"/>
3999 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
4000 <speciesReference species="M_oaa_c" stoichiometry="1.000000"/>
4001 </listOfReactants>
4002 <listOfProducts>
4003 <speciesReference species="M_cit_c" stoichiometry="1.000000"/>
4004 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
4005 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4006 </listOfProducts>
4007 </reaction>
4008 <reaction id="R_CSND" name="R_Cytosine_deaminase" reversible="false">
4009 <notes>
4010 <html:p>GENE_ASSOCIATION: b0337</html:p>
4011 <html:p>PROTEIN_ASSOCIATION: CodA</html:p>
4012 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
4013 <html:p>PROTEIN_CLASS: 3.5.4.1</html:p>
4014 </notes>
4015 <listOfReactants>
4016 <speciesReference species="M_csn_c" stoichiometry="1.000000"/>
4017 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4018 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
4019 </listOfReactants>
4020 <listOfProducts>
4021 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
4022 <speciesReference species="M_ura_c" stoichiometry="1.000000"/>
4023 </listOfProducts>
4024 </reaction>
4025 <reaction id="R_CSNt2" name="R_cytosine_transport_in_via_proton_symport" reversible="false">
4026 <notes>
4027 <html:p>GENE_ASSOCIATION: b0336</html:p>
4028 <html:p>PROTEIN_ASSOCIATION: CodB</html:p>
4029 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
4030 <html:p>PROTEIN_CLASS: </html:p>
4031 </notes>
4032 <listOfReactants>
4033 <speciesReference species="M_csn_e" stoichiometry="1.000000"/>
4034 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
4035 </listOfReactants>
4036 <listOfProducts>
4037 <speciesReference species="M_csn_c" stoichiometry="1.000000"/>
4038 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4039 </listOfProducts>
4040 </reaction>
4041 <reaction id="R_CTPS2" name="R_CTP_synthase__glutamine_" reversible="false">
4042 <notes>
4043 <html:p>GENE_ASSOCIATION: b2780</html:p>
4044 <html:p>PROTEIN_ASSOCIATION: PyrG</html:p>
4045 <html:p>SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis</html:p>
4046 <html:p>PROTEIN_CLASS: 6.3.4.2</html:p>
4047 </notes>
4048 <listOfReactants>
4049 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
4050 <speciesReference species="M_gln_L_c" stoichiometry="1.000000"/>
4051 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
4052 <speciesReference species="M_utp_c" stoichiometry="1.000000"/>
4053 </listOfReactants>
4054 <listOfProducts>
4055 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
4056 <speciesReference species="M_ctp_c" stoichiometry="1.000000"/>
4057 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
4058 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
4059 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
4060 </listOfProducts>
4061 </reaction>
4062 <reaction id="R_CYANST" name="R_Cyanide_sulfurtransferase" reversible="false">
4063 <notes>
4064 <html:p>GENE_ASSOCIATION: b3425</html:p>
4065 <html:p>PROTEIN_ASSOCIATION: GlpE</html:p>
4066 <html:p>SUBSYSTEM: S_Unassigned</html:p>
4067 <html:p>PROTEIN_CLASS: 2.8.1.1</html:p>
4068 </notes>
4069 <listOfReactants>
4070 <speciesReference species="M_cyan_c" stoichiometry="1.000000"/>
4071 <speciesReference species="M_tsul_c" stoichiometry="1.000000"/>
4072 </listOfReactants>
4073 <listOfProducts>
4074 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4075 <speciesReference species="M_so3_c" stoichiometry="1.000000"/>
4076 <speciesReference species="M_tcynt_c" stoichiometry="1.000000"/>
4077 </listOfProducts>
4078 </reaction>
4079 <reaction id="R_CYNTAH" name="R_Cyanate_aminohydrolase" reversible="false">
4080 <notes>
4081 <html:p>GENE_ASSOCIATION: b0340</html:p>
4082 <html:p>PROTEIN_ASSOCIATION: CynS</html:p>
4083 <html:p>SUBSYSTEM: S_Nitrogen_Metabolism</html:p>
4084 <html:p>PROTEIN_CLASS: </html:p>
4085 </notes>
4086 <listOfReactants>
4087 <speciesReference species="M_cynt_c" stoichiometry="1.000000"/>
4088 <speciesReference species="M_h_c" stoichiometry="3.000000"/>
4089 <speciesReference species="M_hco3_c" stoichiometry="1.000000"/>
4090 </listOfReactants>
4091 <listOfProducts>
4092 <speciesReference species="M_co2_c" stoichiometry="2.000000"/>
4093 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
4094 </listOfProducts>
4095 </reaction>
4096 <reaction id="R_CYNTt2" name="R_Cyanate_transport_via_proton_symport" reversible="false">
4097 <notes>
4098 <html:p>GENE_ASSOCIATION: b0341</html:p>
4099 <html:p>PROTEIN_ASSOCIATION: CynX</html:p>
4100 <html:p>SUBSYSTEM: S_Putative_Transporters</html:p>
4101 <html:p>PROTEIN_CLASS: </html:p>
4102 </notes>
4103 <listOfReactants>
4104 <speciesReference species="M_cynt_e" stoichiometry="1.000000"/>
4105 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
4106 </listOfReactants>
4107 <listOfProducts>
4108 <speciesReference species="M_cynt_c" stoichiometry="1.000000"/>
4109 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4110 </listOfProducts>
4111 </reaction>
4112 <reaction id="R_CYSDS" name="R_Cysteine_Desulfhydrase" reversible="false">
4113 <notes>
4114 <html:p>GENE_ASSOCIATION: b3708</html:p>
4115 <html:p>PROTEIN_ASSOCIATION: TnaA</html:p>
4116 <html:p>SUBSYSTEM: S_Cysteine_Metabolism</html:p>
4117 <html:p>PROTEIN_CLASS: 4.1.99.1</html:p>
4118 </notes>
4119 <listOfReactants>
4120 <speciesReference species="M_cys_L_c" stoichiometry="1.000000"/>
4121 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
4122 </listOfReactants>
4123 <listOfProducts>
4124 <speciesReference species="M_h2s_c" stoichiometry="1.000000"/>
4125 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
4126 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
4127 </listOfProducts>
4128 </reaction>
4129 <reaction id="R_CYSS" name="R_cysteine_synthase" reversible="false">
4130 <notes>
4131 <html:p>GENE_ASSOCIATION: ( b2414 or b2421 )</html:p>
4132 <html:p>PROTEIN_ASSOCIATION: ( CysKec ) or ( CysM )</html:p>
4133 <html:p>SUBSYSTEM: S_Cysteine_Metabolism</html:p>
4134 <html:p>PROTEIN_CLASS: </html:p>
4135 </notes>
4136 <listOfReactants>
4137 <speciesReference species="M_acser_c" stoichiometry="1.000000"/>
4138 <speciesReference species="M_h2s_c" stoichiometry="1.000000"/>
4139 </listOfReactants>
4140 <listOfProducts>
4141 <speciesReference species="M_ac_c" stoichiometry="1.000000"/>
4142 <speciesReference species="M_cys_L_c" stoichiometry="1.000000"/>
4143 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4144 </listOfProducts>
4145 </reaction>
4146 <reaction id="R_CYSTL" name="R_cystathionine_b_lyase" reversible="false">
4147 <notes>
4148 <html:p>GENE_ASSOCIATION: ( b3008 or b1622 )</html:p>
4149 <html:p>PROTEIN_ASSOCIATION: ( MetC ) or ( MalY )</html:p>
4150 <html:p>SUBSYSTEM: S_Methionine_Metabolism</html:p>
4151 <html:p>PROTEIN_CLASS: 4.4.1.8</html:p>
4152 </notes>
4153 <listOfReactants>
4154 <speciesReference species="M_cyst_L_c" stoichiometry="1.000000"/>
4155 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
4156 </listOfReactants>
4157 <listOfProducts>
4158 <speciesReference species="M_hcys_L_c" stoichiometry="1.000000"/>
4159 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
4160 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
4161 </listOfProducts>
4162 </reaction>
4163 <reaction id="R_CYSabc" name="R_L_cysteine_transport_via_ABC_system" reversible="false">
4164 <notes>
4165 <html:p>GENE_ASSOCIATION: </html:p>
4166 <html:p>PROTEIN_ASSOCIATION: </html:p>
4167 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
4168 <html:p>PROTEIN_CLASS: </html:p>
4169 </notes>
4170 <listOfReactants>
4171 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
4172 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
4173 <speciesReference species="M_cys_L_e" stoichiometry="1.000000"/>
4174 </listOfReactants>
4175 <listOfProducts>
4176 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
4177 <speciesReference species="M_cys_L_c" stoichiometry="1.000000"/>
4178 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4179 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
4180 </listOfProducts>
4181 </reaction>
4182 <reaction id="R_CYTBD" name="R_cytochrome_oxidase_bd__ubiquinol_8_2_protons_" reversible="false">
4183 <notes>
4184 <html:p>GENE_ASSOCIATION: ( b0733 and b0734 )</html:p>
4185 <html:p>PROTEIN_ASSOCIATION: CydA</html:p>
4186 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
4187 <html:p>PROTEIN_CLASS: </html:p>
4188 </notes>
4189 <listOfReactants>
4190 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
4191 <speciesReference species="M_o2_c" stoichiometry="0.500000"/>
4192 <speciesReference species="M_q8h2_c" stoichiometry="1.000000"/>
4193 </listOfReactants>
4194 <listOfProducts>
4195 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
4196 <speciesReference species="M_q8_c" stoichiometry="1.000000"/>
4197 <speciesReference species="M_h_e" stoichiometry="2.000000"/>
4198 </listOfProducts>
4199 </reaction>
4200 <reaction id="R_CYTBO3" name="R_cytochrome_oxidase_bo3__ubiquinol_8_25_protons_" reversible="false">
4201 <notes>
4202 <html:p>GENE_ASSOCIATION: ( b0429 and b0430 and b0431 and b0432 )</html:p>
4203 <html:p>PROTEIN_ASSOCIATION: CyoA</html:p>
4204 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
4205 <html:p>PROTEIN_CLASS: </html:p>
4206 </notes>
4207 <listOfReactants>
4208 <speciesReference species="M_h_c" stoichiometry="2.500000"/>
4209 <speciesReference species="M_o2_c" stoichiometry="0.500000"/>
4210 <speciesReference species="M_q8h2_c" stoichiometry="1.000000"/>
4211 </listOfReactants>
4212 <listOfProducts>
4213 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
4214 <speciesReference species="M_q8_c" stoichiometry="1.000000"/>
4215 <speciesReference species="M_h_e" stoichiometry="2.500000"/>
4216 </listOfProducts>
4217 </reaction>
4218 <reaction id="R_CYTD" name="R_cytidine_deaminase" reversible="false">
4219 <notes>
4220 <html:p>GENE_ASSOCIATION: b2143</html:p>
4221 <html:p>PROTEIN_ASSOCIATION: Cdd</html:p>
4222 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
4223 <html:p>PROTEIN_CLASS: 3.5.4.5</html:p>
4224 </notes>
4225 <listOfReactants>
4226 <speciesReference species="M_cytd_c" stoichiometry="1.000000"/>
4227 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4228 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
4229 </listOfReactants>
4230 <listOfProducts>
4231 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
4232 <speciesReference species="M_uri_c" stoichiometry="1.000000"/>
4233 </listOfProducts>
4234 </reaction>
4235 <reaction id="R_CYTDK2" name="R_cytidine_kinase__GTP_" reversible="false">
4236 <notes>
4237 <html:p>GENE_ASSOCIATION: b2066</html:p>
4238 <html:p>PROTEIN_ASSOCIATION: Udk</html:p>
4239 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
4240 <html:p>PROTEIN_CLASS: </html:p>
4241 </notes>
4242 <listOfReactants>
4243 <speciesReference species="M_cytd_c" stoichiometry="1.000000"/>
4244 <speciesReference species="M_gtp_c" stoichiometry="1.000000"/>
4245 </listOfReactants>
4246 <listOfProducts>
4247 <speciesReference species="M_cmp_c" stoichiometry="1.000000"/>
4248 <speciesReference species="M_gdp_c" stoichiometry="1.000000"/>
4249 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4250 </listOfProducts>
4251 </reaction>
4252 <reaction id="R_CYTDt2" name="R_cytidine_transport_in_via_proton_symport" reversible="false">
4253 <notes>
4254 <html:p>GENE_ASSOCIATION: ( b2964 or b2393 )</html:p>
4255 <html:p>PROTEIN_ASSOCIATION: ( NupG ) or ( NupCec )</html:p>
4256 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
4257 <html:p>PROTEIN_CLASS: </html:p>
4258 </notes>
4259 <listOfReactants>
4260 <speciesReference species="M_cytd_e" stoichiometry="1.000000"/>
4261 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
4262 </listOfReactants>
4263 <listOfProducts>
4264 <speciesReference species="M_cytd_c" stoichiometry="1.000000"/>
4265 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4266 </listOfProducts>
4267 </reaction>
4268 <reaction id="R_CYTDt2r" name="R_cytidine_transport_in_via_proton_symport__reversible" reversible="true">
4269 <notes>
4270 <html:p>GENE_ASSOCIATION: b2406</html:p>
4271 <html:p>PROTEIN_ASSOCIATION: XapB</html:p>
4272 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
4273 <html:p>PROTEIN_CLASS: </html:p>
4274 </notes>
4275 <listOfReactants>
4276 <speciesReference species="M_cytd_e" stoichiometry="1.000000"/>
4277 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
4278 </listOfReactants>
4279 <listOfProducts>
4280 <speciesReference species="M_cytd_c" stoichiometry="1.000000"/>
4281 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4282 </listOfProducts>
4283 </reaction>
4284 <reaction id="R_CYTK1" name="R_cytidylate_kinase__CMP_" reversible="true">
4285 <notes>
4286 <html:p>GENE_ASSOCIATION: b0910</html:p>
4287 <html:p>PROTEIN_ASSOCIATION: Cmk</html:p>
4288 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
4289 <html:p>PROTEIN_CLASS: 2.7.4.14</html:p>
4290 </notes>
4291 <listOfReactants>
4292 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
4293 <speciesReference species="M_cmp_c" stoichiometry="1.000000"/>
4294 </listOfReactants>
4295 <listOfProducts>
4296 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
4297 <speciesReference species="M_cdp_c" stoichiometry="1.000000"/>
4298 </listOfProducts>
4299 </reaction>
4300 <reaction id="R_CYTK2" name="R_cytidylate_kinase__dCMP_" reversible="true">
4301 <notes>
4302 <html:p>GENE_ASSOCIATION: b0910</html:p>
4303 <html:p>PROTEIN_ASSOCIATION: Cmk</html:p>
4304 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
4305 <html:p>PROTEIN_CLASS: 2.7.4.14</html:p>
4306 </notes>
4307 <listOfReactants>
4308 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
4309 <speciesReference species="M_dcmp_c" stoichiometry="1.000000"/>
4310 </listOfReactants>
4311 <listOfProducts>
4312 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
4313 <speciesReference species="M_dcdp_c" stoichiometry="1.000000"/>
4314 </listOfProducts>
4315 </reaction>
4316 <reaction id="R_DAAD" name="R_D_Amino_acid_dehydrogenase" reversible="false">
4317 <notes>
4318 <html:p>GENE_ASSOCIATION: b1189</html:p>
4319 <html:p>PROTEIN_ASSOCIATION: DadA</html:p>
4320 <html:p>SUBSYSTEM: S_Alanine_and_Aspartate_Metabolism</html:p>
4321 <html:p>PROTEIN_CLASS: 1.4.99.1</html:p>
4322 </notes>
4323 <listOfReactants>
4324 <speciesReference species="M_ala_D_c" stoichiometry="1.000000"/>
4325 <speciesReference species="M_fad_c" stoichiometry="1.000000"/>
4326 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
4327 </listOfReactants>
4328 <listOfProducts>
4329 <speciesReference species="M_fadh2_c" stoichiometry="1.000000"/>
4330 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
4331 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
4332 </listOfProducts>
4333 </reaction>
4334 <reaction id="R_DADA" name="R_Deoxyadenosine_deaminase" reversible="false">
4335 <notes>
4336 <html:p>GENE_ASSOCIATION: b1623</html:p>
4337 <html:p>PROTEIN_ASSOCIATION: Add</html:p>
4338 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
4339 <html:p>PROTEIN_CLASS: </html:p>
4340 </notes>
4341 <listOfReactants>
4342 <speciesReference species="M_dad_2_c" stoichiometry="1.000000"/>
4343 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4344 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
4345 </listOfReactants>
4346 <listOfProducts>
4347 <speciesReference species="M_din_c" stoichiometry="1.000000"/>
4348 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
4349 </listOfProducts>
4350 </reaction>
4351 <reaction id="R_DADK" name="R_deoxyadenylate_kinase" reversible="true">
4352 <notes>
4353 <html:p>GENE_ASSOCIATION: b0474</html:p>
4354 <html:p>PROTEIN_ASSOCIATION: Adk</html:p>
4355 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
4356 <html:p>PROTEIN_CLASS: 2.7.4.11</html:p>
4357 </notes>
4358 <listOfReactants>
4359 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
4360 <speciesReference species="M_damp_c" stoichiometry="1.000000"/>
4361 </listOfReactants>
4362 <listOfProducts>
4363 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
4364 <speciesReference species="M_dadp_c" stoichiometry="1.000000"/>
4365 </listOfProducts>
4366 </reaction>
4367 <reaction id="R_DADNt2" name="R_deoxyadenosine_transport_in_via_proton_symport" reversible="false">
4368 <notes>
4369 <html:p>GENE_ASSOCIATION: ( b2964 or b2393 )</html:p>
4370 <html:p>PROTEIN_ASSOCIATION: ( NupG ) or ( NupCec )</html:p>
4371 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
4372 <html:p>PROTEIN_CLASS: </html:p>
4373 </notes>
4374 <listOfReactants>
4375 <speciesReference species="M_dad_2_e" stoichiometry="1.000000"/>
4376 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
4377 </listOfReactants>
4378 <listOfProducts>
4379 <speciesReference species="M_dad_2_c" stoichiometry="1.000000"/>
4380 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4381 </listOfProducts>
4382 </reaction>
4383 <reaction id="R_DAGK_EC" name="R_Diacylglycerol_kinase" reversible="false">
4384 <notes>
4385 <html:p>GENE_ASSOCIATION: b4042</html:p>
4386 <html:p>PROTEIN_ASSOCIATION: DgkA</html:p>
4387 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
4388 <html:p>PROTEIN_CLASS: 2.7.1.107</html:p>
4389 </notes>
4390 <listOfReactants>
4391 <speciesReference species="M_12dgr_EC_c" stoichiometry="0.020000"/>
4392 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
4393 </listOfReactants>
4394 <listOfProducts>
4395 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
4396 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4397 <speciesReference species="M_pa_EC_c" stoichiometry="0.020000"/>
4398 </listOfProducts>
4399 </reaction>
4400 <reaction id="R_DALAt2r" name="R_D_alanine_transport_via_proton_symport" reversible="true">
4401 <notes>
4402 <html:p>GENE_ASSOCIATION: b4208</html:p>
4403 <html:p>PROTEIN_ASSOCIATION: CycAec</html:p>
4404 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
4405 <html:p>PROTEIN_CLASS: </html:p>
4406 </notes>
4407 <listOfReactants>
4408 <speciesReference species="M_ala_D_e" stoichiometry="1.000000"/>
4409 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
4410 </listOfReactants>
4411 <listOfProducts>
4412 <speciesReference species="M_ala_D_c" stoichiometry="1.000000"/>
4413 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4414 </listOfProducts>
4415 </reaction>
4416 <reaction id="R_DAPDC" name="R_diaminopimelate_decarboxylase" reversible="false">
4417 <notes>
4418 <html:p>GENE_ASSOCIATION: b2838</html:p>
4419 <html:p>PROTEIN_ASSOCIATION: LysA</html:p>
4420 <html:p>SUBSYSTEM: S_Threonine_and_Lysine_Metabolism</html:p>
4421 <html:p>PROTEIN_CLASS: 4.1.1.20</html:p>
4422 </notes>
4423 <listOfReactants>
4424 <speciesReference species="M_26dap_M_c" stoichiometry="1.000000"/>
4425 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4426 </listOfReactants>
4427 <listOfProducts>
4428 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
4429 <speciesReference species="M_lys_L_c" stoichiometry="1.000000"/>
4430 </listOfProducts>
4431 </reaction>
4432 <reaction id="R_DAPE" name="R_diaminopimelate_epimerase" reversible="true">
4433 <notes>
4434 <html:p>GENE_ASSOCIATION: b3809</html:p>
4435 <html:p>PROTEIN_ASSOCIATION: DapF</html:p>
4436 <html:p>SUBSYSTEM: S_Threonine_and_Lysine_Metabolism</html:p>
4437 <html:p>PROTEIN_CLASS: 5.1.1.7</html:p>
4438 </notes>
4439 <listOfReactants>
4440 <speciesReference species="M_26dap_LL_c" stoichiometry="1.000000"/>
4441 </listOfReactants>
4442 <listOfProducts>
4443 <speciesReference species="M_26dap_M_c" stoichiometry="1.000000"/>
4444 </listOfProducts>
4445 </reaction>
4446 <reaction id="R_DAPabc" name="R_M_diaminopimelic_acid_ABC_transport" reversible="false">
4447 <notes>
4448 <html:p>GENE_ASSOCIATION: </html:p>
4449 <html:p>PROTEIN_ASSOCIATION: </html:p>
4450 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
4451 <html:p>PROTEIN_CLASS: </html:p>
4452 </notes>
4453 <listOfReactants>
4454 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
4455 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
4456 <speciesReference species="M_26dap_M_e" stoichiometry="1.000000"/>
4457 </listOfReactants>
4458 <listOfProducts>
4459 <speciesReference species="M_26dap_M_c" stoichiometry="1.000000"/>
4460 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
4461 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4462 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
4463 </listOfProducts>
4464 </reaction>
4465 <reaction id="R_DASYN_EC" name="R_CDP_Diacylglycerol_synthetase__Ecoli_" reversible="true">
4466 <notes>
4467 <html:p>GENE_ASSOCIATION: b0175</html:p>
4468 <html:p>PROTEIN_ASSOCIATION: CdsA</html:p>
4469 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
4470 <html:p>PROTEIN_CLASS: 2.7.7.41</html:p>
4471 </notes>
4472 <listOfReactants>
4473 <speciesReference species="M_ctp_c" stoichiometry="1.000000"/>
4474 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4475 <speciesReference species="M_pa_EC_c" stoichiometry="0.020000"/>
4476 </listOfReactants>
4477 <listOfProducts>
4478 <speciesReference species="M_cdpdag_EC_c" stoichiometry="0.020000"/>
4479 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
4480 </listOfProducts>
4481 </reaction>
4482 <reaction id="R_DB4PS" name="R_3_4_Dihydroxy_2_butanone_4_phosphate_synthase" reversible="false">
4483 <notes>
4484 <html:p>GENE_ASSOCIATION: b3041</html:p>
4485 <html:p>PROTEIN_ASSOCIATION: RibBec</html:p>
4486 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
4487 <html:p>PROTEIN_CLASS: </html:p>
4488 </notes>
4489 <listOfReactants>
4490 <speciesReference species="M_ru5p_D_c" stoichiometry="1.000000"/>
4491 </listOfReactants>
4492 <listOfProducts>
4493 <speciesReference species="M_db4p_c" stoichiometry="1.000000"/>
4494 <speciesReference species="M_for_c" stoichiometry="1.000000"/>
4495 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4496 </listOfProducts>
4497 </reaction>
4498 <reaction id="R_DBTSr" name="R_dethiobiotin_synthase" reversible="true">
4499 <notes>
4500 <html:p>GENE_ASSOCIATION: b0778</html:p>
4501 <html:p>PROTEIN_ASSOCIATION: BioDec</html:p>
4502 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
4503 <html:p>PROTEIN_CLASS: 6.3.3.3</html:p>
4504 </notes>
4505 <listOfReactants>
4506 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
4507 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
4508 <speciesReference species="M_dann_c" stoichiometry="1.000000"/>
4509 </listOfReactants>
4510 <listOfProducts>
4511 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
4512 <speciesReference species="M_dtbt_c" stoichiometry="1.000000"/>
4513 <speciesReference species="M_h_c" stoichiometry="3.000000"/>
4514 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
4515 </listOfProducts>
4516 </reaction>
4517 <reaction id="R_DCTPD" name="R_dCTP_deaminase" reversible="false">
4518 <notes>
4519 <html:p>GENE_ASSOCIATION: b2065</html:p>
4520 <html:p>PROTEIN_ASSOCIATION: Dcd</html:p>
4521 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
4522 <html:p>PROTEIN_CLASS: 3.5.4.13</html:p>
4523 </notes>
4524 <listOfReactants>
4525 <speciesReference species="M_dctp_c" stoichiometry="1.000000"/>
4526 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4527 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
4528 </listOfReactants>
4529 <listOfProducts>
4530 <speciesReference species="M_dutp_c" stoichiometry="1.000000"/>
4531 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
4532 </listOfProducts>
4533 </reaction>
4534 <reaction id="R_DCYTD" name="R_deoxycytidine_deaminase" reversible="false">
4535 <notes>
4536 <html:p>GENE_ASSOCIATION: b2143</html:p>
4537 <html:p>PROTEIN_ASSOCIATION: Cdd</html:p>
4538 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
4539 <html:p>PROTEIN_CLASS: 3.5.4.14</html:p>
4540 </notes>
4541 <listOfReactants>
4542 <speciesReference species="M_dcyt_c" stoichiometry="1.000000"/>
4543 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4544 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
4545 </listOfReactants>
4546 <listOfProducts>
4547 <speciesReference species="M_duri_c" stoichiometry="1.000000"/>
4548 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
4549 </listOfProducts>
4550 </reaction>
4551 <reaction id="R_DCYTt2" name="R_deoxycytidine_transport_in_via_proton_symport" reversible="false">
4552 <notes>
4553 <html:p>GENE_ASSOCIATION: ( b2964 or b2393 )</html:p>
4554 <html:p>PROTEIN_ASSOCIATION: ( NupG ) or ( NupCec )</html:p>
4555 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
4556 <html:p>PROTEIN_CLASS: </html:p>
4557 </notes>
4558 <listOfReactants>
4559 <speciesReference species="M_dcyt_e" stoichiometry="1.000000"/>
4560 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
4561 </listOfReactants>
4562 <listOfProducts>
4563 <speciesReference species="M_dcyt_c" stoichiometry="1.000000"/>
4564 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4565 </listOfProducts>
4566 </reaction>
4567 <reaction id="R_DDGALK" name="R_2_dehydro_3_deoxygalactonokinase" reversible="false">
4568 <notes>
4569 <html:p>GENE_ASSOCIATION: b3693</html:p>
4570 <html:p>PROTEIN_ASSOCIATION: DgoK</html:p>
4571 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
4572 <html:p>PROTEIN_CLASS: 2.7.1.58</html:p>
4573 </notes>
4574 <listOfReactants>
4575 <speciesReference species="M_2dh3dgal_c" stoichiometry="1.000000"/>
4576 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
4577 </listOfReactants>
4578 <listOfProducts>
4579 <speciesReference species="M_2dh3dgal6p_c" stoichiometry="1.000000"/>
4580 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
4581 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4582 </listOfProducts>
4583 </reaction>
4584 <reaction id="R_DDGLCNt2r" name="R_2_dehydro_3_deoxy_D_gluconate_transport_via_proton_symport__reversible" reversible="true">
4585 <notes>
4586 <html:p>GENE_ASSOCIATION: b3909</html:p>
4587 <html:p>PROTEIN_ASSOCIATION: KdgT</html:p>
4588 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
4589 <html:p>PROTEIN_CLASS: </html:p>
4590 </notes>
4591 <listOfReactants>
4592 <speciesReference species="M_2ddglcn_e" stoichiometry="1.000000"/>
4593 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
4594 </listOfReactants>
4595 <listOfProducts>
4596 <speciesReference species="M_2ddglcn_c" stoichiometry="1.000000"/>
4597 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4598 </listOfProducts>
4599 </reaction>
4600 <reaction id="R_DDGLK" name="R_2_dehydro_3_deoxygluconokinase" reversible="false">
4601 <notes>
4602 <html:p>GENE_ASSOCIATION: b3526</html:p>
4603 <html:p>PROTEIN_ASSOCIATION: KdgK</html:p>
4604 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
4605 <html:p>PROTEIN_CLASS: 2.7.1.45</html:p>
4606 </notes>
4607 <listOfReactants>
4608 <speciesReference species="M_2ddglcn_c" stoichiometry="1.000000"/>
4609 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
4610 </listOfReactants>
4611 <listOfProducts>
4612 <speciesReference species="M_2ddg6p_c" stoichiometry="1.000000"/>
4613 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
4614 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4615 </listOfProducts>
4616 </reaction>
4617 <reaction id="R_DDPA" name="R_3_deoxy_D_arabino_heptulosonate_7_phosphate_synthetase" reversible="false">
4618 <notes>
4619 <html:p>GENE_ASSOCIATION: ( b2601 or b0754 or b1704 )</html:p>
4620 <html:p>PROTEIN_ASSOCIATION: ( AroF ) or ( AroGec ) or ( AroH )</html:p>
4621 <html:p>SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism</html:p>
4622 <html:p>PROTEIN_CLASS: 4.1.2.15</html:p>
4623 </notes>
4624 <listOfReactants>
4625 <speciesReference species="M_e4p_c" stoichiometry="1.000000"/>
4626 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
4627 <speciesReference species="M_pep_c" stoichiometry="1.000000"/>
4628 </listOfReactants>
4629 <listOfProducts>
4630 <speciesReference species="M_2dda7p_c" stoichiometry="1.000000"/>
4631 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
4632 </listOfProducts>
4633 </reaction>
4634 <reaction id="R_DDPGALA" name="R_2_dehydro_3_deoxy_6_phosphogalactonate_aldolase" reversible="true">
4635 <notes>
4636 <html:p>GENE_ASSOCIATION: b3692</html:p>
4637 <html:p>PROTEIN_ASSOCIATION: DgoA</html:p>
4638 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
4639 <html:p>PROTEIN_CLASS: 4.1.2.21</html:p>
4640 </notes>
4641 <listOfReactants>
4642 <speciesReference species="M_2dh3dgal6p_c" stoichiometry="1.000000"/>
4643 </listOfReactants>
4644 <listOfProducts>
4645 <speciesReference species="M_g3p_c" stoichiometry="1.000000"/>
4646 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
4647 </listOfProducts>
4648 </reaction>
4649 <reaction id="R_DGK1" name="R_deoxyguanylate_kinase__dGMPATP_" reversible="true">
4650 <notes>
4651 <html:p>GENE_ASSOCIATION: b3648</html:p>
4652 <html:p>PROTEIN_ASSOCIATION: Gmkec</html:p>
4653 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
4654 <html:p>PROTEIN_CLASS: 2.7.4.8</html:p>
4655 </notes>
4656 <listOfReactants>
4657 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
4658 <speciesReference species="M_dgmp_c" stoichiometry="1.000000"/>
4659 </listOfReactants>
4660 <listOfProducts>
4661 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
4662 <speciesReference species="M_dgdp_c" stoichiometry="1.000000"/>
4663 </listOfProducts>
4664 </reaction>
4665 <reaction id="R_DGSNt2" name="R_deoxyguanosine_transport_in_via_proton_symport" reversible="false">
4666 <notes>
4667 <html:p>GENE_ASSOCIATION: b2964</html:p>
4668 <html:p>PROTEIN_ASSOCIATION: NupG</html:p>
4669 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
4670 <html:p>PROTEIN_CLASS: </html:p>
4671 </notes>
4672 <listOfReactants>
4673 <speciesReference species="M_dgsn_e" stoichiometry="1.000000"/>
4674 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
4675 </listOfReactants>
4676 <listOfProducts>
4677 <speciesReference species="M_dgsn_c" stoichiometry="1.000000"/>
4678 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4679 </listOfProducts>
4680 </reaction>
4681 <reaction id="R_DHAD1" name="R_dihydroxy_acid_dehydratase__2_3_dihydroxy_3_methylbutanoate_" reversible="false">
4682 <notes>
4683 <html:p>GENE_ASSOCIATION: b3771</html:p>
4684 <html:p>PROTEIN_ASSOCIATION: IlvD</html:p>
4685 <html:p>SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism</html:p>
4686 <html:p>PROTEIN_CLASS: 4.2.1.9</html:p>
4687 </notes>
4688 <listOfReactants>
4689 <speciesReference species="M_23dhmb_c" stoichiometry="1.000000"/>
4690 </listOfReactants>
4691 <listOfProducts>
4692 <speciesReference species="M_3mob_c" stoichiometry="1.000000"/>
4693 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
4694 </listOfProducts>
4695 </reaction>
4696 <reaction id="R_DHAD2" name="R_Dihydroxy_acid_dehydratase__2_3_dihydroxy_3_methylpentanoate_" reversible="false">
4697 <notes>
4698 <html:p>GENE_ASSOCIATION: b3771</html:p>
4699 <html:p>PROTEIN_ASSOCIATION: IlvD</html:p>
4700 <html:p>SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism</html:p>
4701 <html:p>PROTEIN_CLASS: </html:p>
4702 </notes>
4703 <listOfReactants>
4704 <speciesReference species="M_23dhmp_c" stoichiometry="1.000000"/>
4705 </listOfReactants>
4706 <listOfProducts>
4707 <speciesReference species="M_3mop_c" stoichiometry="1.000000"/>
4708 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
4709 </listOfProducts>
4710 </reaction>
4711 <reaction id="R_DHAPT" name="R_Dihydroxyacetone_phosphotransferase" reversible="false">
4712 <notes>
4713 <html:p>GENE_ASSOCIATION: ( b1200 and b1199 and b1198 and b2415 and b2416 )</html:p>
4714 <html:p>PROTEIN_ASSOCIATION: ( DhaK and DhaL and DhaM and PtsH and PtsI )</html:p>
4715 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
4716 <html:p>PROTEIN_CLASS: </html:p>
4717 </notes>
4718 <listOfReactants>
4719 <speciesReference species="M_dha_c" stoichiometry="1.000000"/>
4720 <speciesReference species="M_pep_c" stoichiometry="1.000000"/>
4721 </listOfReactants>
4722 <listOfProducts>
4723 <speciesReference species="M_dhap_c" stoichiometry="1.000000"/>
4724 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
4725 </listOfProducts>
4726 </reaction>
4727 <reaction id="R_DHAt" name="R_Dihydroxyacetone_transport_via_facilitated_diffusion" reversible="true">
4728 <notes>
4729 <html:p>GENE_ASSOCIATION: </html:p>
4730 <html:p>PROTEIN_ASSOCIATION: </html:p>
4731 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
4732 <html:p>PROTEIN_CLASS: </html:p>
4733 </notes>
4734 <listOfReactants>
4735 <speciesReference species="M_dha_e" stoichiometry="1.000000"/>
4736 </listOfReactants>
4737 <listOfProducts>
4738 <speciesReference species="M_dha_c" stoichiometry="1.000000"/>
4739 </listOfProducts>
4740 </reaction>
4741 <reaction id="R_DHBD" name="R_2_3_dihydro_2_3_dihydroxybenzoate_dehydrogenase" reversible="true">
4742 <notes>
4743 <html:p>GENE_ASSOCIATION: b0596</html:p>
4744 <html:p>PROTEIN_ASSOCIATION: EntA</html:p>
4745 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
4746 <html:p>PROTEIN_CLASS: 1.3.1.28</html:p>
4747 </notes>
4748 <listOfReactants>
4749 <speciesReference species="M_23ddhb_c" stoichiometry="1.000000"/>
4750 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
4751 </listOfReactants>
4752 <listOfProducts>
4753 <speciesReference species="M_23dhb_c" stoichiometry="1.000000"/>
4754 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4755 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
4756 </listOfProducts>
4757 </reaction>
4758 <reaction id="R_DHBSr" name="R_2_3_dihydroxybenzoate_adenylate_synthase" reversible="true">
4759 <notes>
4760 <html:p>GENE_ASSOCIATION: b0594</html:p>
4761 <html:p>PROTEIN_ASSOCIATION: EntE</html:p>
4762 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
4763 <html:p>PROTEIN_CLASS: 2.7.7.58</html:p>
4764 </notes>
4765 <listOfReactants>
4766 <speciesReference species="M_23dhb_c" stoichiometry="1.000000"/>
4767 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
4768 </listOfReactants>
4769 <listOfProducts>
4770 <speciesReference species="M_23dhba_c" stoichiometry="1.000000"/>
4771 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
4772 </listOfProducts>
4773 </reaction>
4774 <reaction id="R_DHCIND" name="R_2_3_dihydroxycinnamate_dehydrogenase" reversible="false">
4775 <notes>
4776 <html:p>GENE_ASSOCIATION: b2541</html:p>
4777 <html:p>PROTEIN_ASSOCIATION: HcaB</html:p>
4778 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
4779 <html:p>PROTEIN_CLASS: </html:p>
4780 </notes>
4781 <listOfReactants>
4782 <speciesReference species="M_cenchddd_c" stoichiometry="1.000000"/>
4783 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
4784 </listOfReactants>
4785 <listOfProducts>
4786 <speciesReference species="M_dhcinnm_c" stoichiometry="1.000000"/>
4787 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4788 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
4789 </listOfProducts>
4790 </reaction>
4791 <reaction id="R_DHCINDO" name="R_2_3_dihydroxycinnamate_1_2_dioxygenase" reversible="false">
4792 <notes>
4793 <html:p>GENE_ASSOCIATION: b0348</html:p>
4794 <html:p>PROTEIN_ASSOCIATION: MhpB</html:p>
4795 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
4796 <html:p>PROTEIN_CLASS: </html:p>
4797 </notes>
4798 <listOfReactants>
4799 <speciesReference species="M_dhcinnm_c" stoichiometry="1.000000"/>
4800 <speciesReference species="M_o2_c" stoichiometry="1.000000"/>
4801 </listOfReactants>
4802 <listOfProducts>
4803 <speciesReference species="M_hkntd_c" stoichiometry="1.000000"/>
4804 </listOfProducts>
4805 </reaction>
4806 <reaction id="R_DHDPRy" name="R_dihydrodipicolinate_reductase__NADPH_" reversible="false">
4807 <notes>
4808 <html:p>GENE_ASSOCIATION: b0031</html:p>
4809 <html:p>PROTEIN_ASSOCIATION: DapB</html:p>
4810 <html:p>SUBSYSTEM: S_Threonine_and_Lysine_Metabolism</html:p>
4811 <html:p>PROTEIN_CLASS: 1.3.1.26</html:p>
4812 </notes>
4813 <listOfReactants>
4814 <speciesReference species="M_23dhdp_c" stoichiometry="1.000000"/>
4815 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4816 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
4817 </listOfReactants>
4818 <listOfProducts>
4819 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
4820 <speciesReference species="M_thdp_c" stoichiometry="1.000000"/>
4821 </listOfProducts>
4822 </reaction>
4823 <reaction id="R_DHDPS" name="R_dihydrodipicolinate_synthase" reversible="false">
4824 <notes>
4825 <html:p>GENE_ASSOCIATION: b2478</html:p>
4826 <html:p>PROTEIN_ASSOCIATION: DapA</html:p>
4827 <html:p>SUBSYSTEM: S_Threonine_and_Lysine_Metabolism</html:p>
4828 <html:p>PROTEIN_CLASS: 4.2.1.52</html:p>
4829 </notes>
4830 <listOfReactants>
4831 <speciesReference species="M_aspsa_c" stoichiometry="1.000000"/>
4832 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
4833 </listOfReactants>
4834 <listOfProducts>
4835 <speciesReference species="M_23dhdp_c" stoichiometry="1.000000"/>
4836 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4837 <speciesReference species="M_h2o_c" stoichiometry="2.000000"/>
4838 </listOfProducts>
4839 </reaction>
4840 <reaction id="R_DHFR" name="R_dihydrofolate_reductase" reversible="true">
4841 <notes>
4842 <html:p>GENE_ASSOCIATION: b0048</html:p>
4843 <html:p>PROTEIN_ASSOCIATION: FolA</html:p>
4844 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
4845 <html:p>PROTEIN_CLASS: 1.5.1.3</html:p>
4846 </notes>
4847 <listOfReactants>
4848 <speciesReference species="M_dhf_c" stoichiometry="1.000000"/>
4849 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4850 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
4851 </listOfReactants>
4852 <listOfProducts>
4853 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
4854 <speciesReference species="M_thf_c" stoichiometry="1.000000"/>
4855 </listOfProducts>
4856 </reaction>
4857 <reaction id="R_DHFS" name="R_dihydrofolate_synthase" reversible="false">
4858 <notes>
4859 <html:p>GENE_ASSOCIATION: b2315</html:p>
4860 <html:p>PROTEIN_ASSOCIATION: FolCec</html:p>
4861 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
4862 <html:p>PROTEIN_CLASS: 6.3.2.12</html:p>
4863 </notes>
4864 <listOfReactants>
4865 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
4866 <speciesReference species="M_dhpt_c" stoichiometry="1.000000"/>
4867 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
4868 </listOfReactants>
4869 <listOfProducts>
4870 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
4871 <speciesReference species="M_dhf_c" stoichiometry="1.000000"/>
4872 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
4873 </listOfProducts>
4874 </reaction>
4875 <reaction id="R_DHNAOT" name="R_1_4_dihydroxy_2_naphthoate_octaprenyltransferase" reversible="false">
4876 <notes>
4877 <html:p>GENE_ASSOCIATION: b3930</html:p>
4878 <html:p>PROTEIN_ASSOCIATION: MenA</html:p>
4879 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
4880 <html:p>PROTEIN_CLASS: </html:p>
4881 </notes>
4882 <listOfReactants>
4883 <speciesReference species="M_dhna_c" stoichiometry="1.000000"/>
4884 <speciesReference species="M_octdp_c" stoichiometry="1.000000"/>
4885 </listOfReactants>
4886 <listOfProducts>
4887 <speciesReference species="M_2dmmq8_c" stoichiometry="1.000000"/>
4888 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
4889 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4890 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
4891 </listOfProducts>
4892 </reaction>
4893 <reaction id="R_DHNPA2" name="R_dihydroneopterin_aldolase" reversible="false">
4894 <notes>
4895 <html:p>GENE_ASSOCIATION: b3058</html:p>
4896 <html:p>PROTEIN_ASSOCIATION: FolB</html:p>
4897 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
4898 <html:p>PROTEIN_CLASS: </html:p>
4899 </notes>
4900 <listOfReactants>
4901 <speciesReference species="M_dhnpt_c" stoichiometry="1.000000"/>
4902 </listOfReactants>
4903 <listOfProducts>
4904 <speciesReference species="M_6hmhpt_c" stoichiometry="1.000000"/>
4905 <speciesReference species="M_gcald_c" stoichiometry="1.000000"/>
4906 </listOfProducts>
4907 </reaction>
4908 <reaction id="R_DHORD2" name="R_dihydoorotic_acid_dehydrogenase__quinone8_" reversible="false">
4909 <notes>
4910 <html:p>GENE_ASSOCIATION: b0945</html:p>
4911 <html:p>PROTEIN_ASSOCIATION: PyrD</html:p>
4912 <html:p>SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis</html:p>
4913 <html:p>PROTEIN_CLASS: 1.3.3.1</html:p>
4914 </notes>
4915 <listOfReactants>
4916 <speciesReference species="M_dhor_S_c" stoichiometry="1.000000"/>
4917 <speciesReference species="M_q8_c" stoichiometry="1.000000"/>
4918 </listOfReactants>
4919 <listOfProducts>
4920 <speciesReference species="M_orot_c" stoichiometry="1.000000"/>
4921 <speciesReference species="M_q8h2_c" stoichiometry="1.000000"/>
4922 </listOfProducts>
4923 </reaction>
4924 <reaction id="R_DHORD5" name="R_dihydroorotic_acid__menaquinone_8_" reversible="false">
4925 <notes>
4926 <html:p>GENE_ASSOCIATION: b0945</html:p>
4927 <html:p>PROTEIN_ASSOCIATION: PyrD</html:p>
4928 <html:p>SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis</html:p>
4929 <html:p>PROTEIN_CLASS: 1.3.3.1</html:p>
4930 </notes>
4931 <listOfReactants>
4932 <speciesReference species="M_dhor_S_c" stoichiometry="1.000000"/>
4933 <speciesReference species="M_mqn8_c" stoichiometry="1.000000"/>
4934 </listOfReactants>
4935 <listOfProducts>
4936 <speciesReference species="M_mql8_c" stoichiometry="1.000000"/>
4937 <speciesReference species="M_orot_c" stoichiometry="1.000000"/>
4938 </listOfProducts>
4939 </reaction>
4940 <reaction id="R_DHORTS" name="R_dihydroorotase" reversible="true">
4941 <notes>
4942 <html:p>GENE_ASSOCIATION: b1062</html:p>
4943 <html:p>PROTEIN_ASSOCIATION: PyrC</html:p>
4944 <html:p>SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis</html:p>
4945 <html:p>PROTEIN_CLASS: 3.5.2.3</html:p>
4946 </notes>
4947 <listOfReactants>
4948 <speciesReference species="M_dhor_S_c" stoichiometry="1.000000"/>
4949 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
4950 </listOfReactants>
4951 <listOfProducts>
4952 <speciesReference species="M_cbasp_c" stoichiometry="1.000000"/>
4953 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4954 </listOfProducts>
4955 </reaction>
4956 <reaction id="R_DHPPD" name="R_2_3_dihydroxyphenylpropionate_dehydrogenase" reversible="false">
4957 <notes>
4958 <html:p>GENE_ASSOCIATION: b2541</html:p>
4959 <html:p>PROTEIN_ASSOCIATION: HcaB</html:p>
4960 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
4961 <html:p>PROTEIN_CLASS: </html:p>
4962 </notes>
4963 <listOfReactants>
4964 <speciesReference species="M_cechddd_c" stoichiometry="1.000000"/>
4965 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
4966 </listOfReactants>
4967 <listOfProducts>
4968 <speciesReference species="M_dhpppn_c" stoichiometry="1.000000"/>
4969 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4970 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
4971 </listOfProducts>
4972 </reaction>
4973 <reaction id="R_DHPPDA2" name="R_diaminohydroxyphosphoribosylaminopryrimidine_deaminase__25drapp_" reversible="false">
4974 <notes>
4975 <html:p>GENE_ASSOCIATION: b0414</html:p>
4976 <html:p>PROTEIN_ASSOCIATION: RibDec</html:p>
4977 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
4978 <html:p>PROTEIN_CLASS: 3.5.4.26</html:p>
4979 </notes>
4980 <listOfReactants>
4981 <speciesReference species="M_25drapp_c" stoichiometry="1.000000"/>
4982 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
4983 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
4984 </listOfReactants>
4985 <listOfProducts>
4986 <speciesReference species="M_5apru_c" stoichiometry="1.000000"/>
4987 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
4988 </listOfProducts>
4989 </reaction>
4990 <reaction id="R_DHPS2" name="R_dihydropteroate_synthase" reversible="false">
4991 <notes>
4992 <html:p>GENE_ASSOCIATION: b3177</html:p>
4993 <html:p>PROTEIN_ASSOCIATION: FolP</html:p>
4994 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
4995 <html:p>PROTEIN_CLASS: </html:p>
4996 </notes>
4997 <listOfReactants>
4998 <speciesReference species="M_4abz_c" stoichiometry="1.000000"/>
4999 <speciesReference species="M_6hmhptpp_c" stoichiometry="1.000000"/>
5000 </listOfReactants>
5001 <listOfProducts>
5002 <speciesReference species="M_dhpt_c" stoichiometry="1.000000"/>
5003 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
5004 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
5005 </listOfProducts>
5006 </reaction>
5007 <reaction id="R_DHPTDCs" name="R_4_5_dihydroxy_2_3_pentanedione_cyclization__spontaneous_" reversible="false">
5008 <notes>
5009 <html:p>GENE_ASSOCIATION: </html:p>
5010 <html:p>PROTEIN_ASSOCIATION: </html:p>
5011 <html:p>SUBSYSTEM: S_Methionine_Metabolism</html:p>
5012 <html:p>PROTEIN_CLASS: </html:p>
5013 </notes>
5014 <listOfReactants>
5015 <speciesReference species="M_dhptd_c" stoichiometry="1.000000"/>
5016 </listOfReactants>
5017 <listOfProducts>
5018 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
5019 <speciesReference species="M_hmfurn_c" stoichiometry="1.000000"/>
5020 </listOfProducts>
5021 </reaction>
5022 <reaction id="R_DHQD" name="R_3_dehydroquinate_dehydratase" reversible="true">
5023 <notes>
5024 <html:p>GENE_ASSOCIATION: b1693</html:p>
5025 <html:p>PROTEIN_ASSOCIATION: AroD</html:p>
5026 <html:p>SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism</html:p>
5027 <html:p>PROTEIN_CLASS: 4.2.1.10</html:p>
5028 </notes>
5029 <listOfReactants>
5030 <speciesReference species="M_3dhq_c" stoichiometry="1.000000"/>
5031 </listOfReactants>
5032 <listOfProducts>
5033 <speciesReference species="M_3dhsk_c" stoichiometry="1.000000"/>
5034 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
5035 </listOfProducts>
5036 </reaction>
5037 <reaction id="R_DHQS" name="R_3_dehydroquinate_synthase" reversible="false">
5038 <notes>
5039 <html:p>GENE_ASSOCIATION: b3389</html:p>
5040 <html:p>PROTEIN_ASSOCIATION: AroB</html:p>
5041 <html:p>SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism</html:p>
5042 <html:p>PROTEIN_CLASS: </html:p>
5043 </notes>
5044 <listOfReactants>
5045 <speciesReference species="M_2dda7p_c" stoichiometry="1.000000"/>
5046 </listOfReactants>
5047 <listOfProducts>
5048 <speciesReference species="M_3dhq_c" stoichiometry="1.000000"/>
5049 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
5050 </listOfProducts>
5051 </reaction>
5052 <reaction id="R_DINSt2" name="R_deoxyinosine_transport_in_via_proton_symport" reversible="false">
5053 <notes>
5054 <html:p>GENE_ASSOCIATION: b2964</html:p>
5055 <html:p>PROTEIN_ASSOCIATION: NupG</html:p>
5056 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
5057 <html:p>PROTEIN_CLASS: </html:p>
5058 </notes>
5059 <listOfReactants>
5060 <speciesReference species="M_din_e" stoichiometry="1.000000"/>
5061 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
5062 </listOfReactants>
5063 <listOfProducts>
5064 <speciesReference species="M_din_c" stoichiometry="1.000000"/>
5065 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
5066 </listOfProducts>
5067 </reaction>
5068 <reaction id="R_DKGLCNR1" name="R_2_5_diketo_D_gluconate_reductase" reversible="false">
5069 <notes>
5070 <html:p>GENE_ASSOCIATION: ( b0207 or b3012 )</html:p>
5071 <html:p>PROTEIN_ASSOCIATION: ( DkgB ) or ( DkgA )</html:p>
5072 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
5073 <html:p>PROTEIN_CLASS: </html:p>
5074 </notes>
5075 <listOfReactants>
5076 <speciesReference species="M_25dkglcn_c" stoichiometry="1.000000"/>
5077 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
5078 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
5079 </listOfReactants>
5080 <listOfProducts>
5081 <speciesReference species="M_2dhguln_c" stoichiometry="1.000000"/>
5082 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
5083 </listOfProducts>
5084 </reaction>
5085 <reaction id="R_DKGLCNR2x" name="R_2_5_diketo_D_gluconate_reductase__NADH_" reversible="false">
5086 <notes>
5087 <html:p>GENE_ASSOCIATION: b3553</html:p>
5088 <html:p>PROTEIN_ASSOCIATION: YiaE</html:p>
5089 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
5090 <html:p>PROTEIN_CLASS: </html:p>
5091 </notes>
5092 <listOfReactants>
5093 <speciesReference species="M_25dkglcn_c" stoichiometry="1.000000"/>
5094 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
5095 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
5096 </listOfReactants>
5097 <listOfProducts>
5098 <speciesReference species="M_5dglcn_c" stoichiometry="1.000000"/>
5099 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
5100 </listOfProducts>
5101 </reaction>
5102 <reaction id="R_DKGLCNR2y" name="R_2_5_diketo_D_gluconate_reductase__NADPH_" reversible="false">
5103 <notes>
5104 <html:p>GENE_ASSOCIATION: b3553</html:p>
5105 <html:p>PROTEIN_ASSOCIATION: YiaE</html:p>
5106 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
5107 <html:p>PROTEIN_CLASS: </html:p>
5108 </notes>
5109 <listOfReactants>
5110 <speciesReference species="M_25dkglcn_c" stoichiometry="1.000000"/>
5111 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
5112 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
5113 </listOfReactants>
5114 <listOfProducts>
5115 <speciesReference species="M_5dglcn_c" stoichiometry="1.000000"/>
5116 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
5117 </listOfProducts>
5118 </reaction>
5119 <reaction id="R_DKMPPD" name="R_2_3_diketo_5_methylthio_1_phosphopentane_degradation_reaction" reversible="false">
5120 <notes>
5121 <html:p>GENE_ASSOCIATION: </html:p>
5122 <html:p>PROTEIN_ASSOCIATION: </html:p>
5123 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
5124 <html:p>PROTEIN_CLASS: </html:p>
5125 </notes>
5126 <listOfReactants>
5127 <speciesReference species="M_dkmpp_c" stoichiometry="1.000000"/>
5128 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
5129 <speciesReference species="M_o2_c" stoichiometry="1.000000"/>
5130 </listOfReactants>
5131 <listOfProducts>
5132 <speciesReference species="M_2kmb_c" stoichiometry="1.000000"/>
5133 <speciesReference species="M_for_c" stoichiometry="1.000000"/>
5134 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
5135 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
5136 </listOfProducts>
5137 </reaction>
5138 <reaction id="R_DKMPPD2" name="R_2_3_diketo_5_methylthio_1_phosphopentane_degradation_reaction" reversible="false">
5139 <notes>
5140 <html:p>GENE_ASSOCIATION: </html:p>
5141 <html:p>PROTEIN_ASSOCIATION: </html:p>
5142 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
5143 <html:p>PROTEIN_CLASS: </html:p>
5144 </notes>
5145 <listOfReactants>
5146 <speciesReference species="M_dkmpp_c" stoichiometry="1.000000"/>
5147 <speciesReference species="M_h2o_c" stoichiometry="3.000000"/>
5148 </listOfReactants>
5149 <listOfProducts>
5150 <speciesReference species="M_2kmb_c" stoichiometry="1.000000"/>
5151 <speciesReference species="M_for_c" stoichiometry="1.000000"/>
5152 <speciesReference species="M_h_c" stoichiometry="6.000000"/>
5153 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
5154 </listOfProducts>
5155 </reaction>
5156 <reaction id="R_DMATT" name="R_dimethylallyltranstransferase" reversible="false">
5157 <notes>
5158 <html:p>GENE_ASSOCIATION: b0421</html:p>
5159 <html:p>PROTEIN_ASSOCIATION: IspA</html:p>
5160 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
5161 <html:p>PROTEIN_CLASS: 2.5.1.1</html:p>
5162 </notes>
5163 <listOfReactants>
5164 <speciesReference species="M_dmpp_c" stoichiometry="1.000000"/>
5165 <speciesReference species="M_ipdp_c" stoichiometry="1.000000"/>
5166 </listOfReactants>
5167 <listOfProducts>
5168 <speciesReference species="M_grdp_c" stoichiometry="1.000000"/>
5169 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
5170 </listOfProducts>
5171 </reaction>
5172 <reaction id="R_DMPPS" name="R_1_hydroxy_2_methyl_2__E__butenyl_4_diphosphate_reductase__dmpp_" reversible="false">
5173 <notes>
5174 <html:p>GENE_ASSOCIATION: b0029</html:p>
5175 <html:p>PROTEIN_ASSOCIATION: LytB</html:p>
5176 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
5177 <html:p>PROTEIN_CLASS: </html:p>
5178 </notes>
5179 <listOfReactants>
5180 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
5181 <speciesReference species="M_h2mb4p_c" stoichiometry="1.000000"/>
5182 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
5183 </listOfReactants>
5184 <listOfProducts>
5185 <speciesReference species="M_dmpp_c" stoichiometry="1.000000"/>
5186 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
5187 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
5188 </listOfProducts>
5189 </reaction>
5190 <reaction id="R_DMQMT" name="R_3_Dimethylubiquinonol_3_methyltransferase" reversible="false">
5191 <notes>
5192 <html:p>GENE_ASSOCIATION: b2232</html:p>
5193 <html:p>PROTEIN_ASSOCIATION: UbiG</html:p>
5194 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
5195 <html:p>PROTEIN_CLASS: </html:p>
5196 </notes>
5197 <listOfReactants>
5198 <speciesReference species="M_2omhmbl_c" stoichiometry="1.000000"/>
5199 <speciesReference species="M_amet_c" stoichiometry="1.000000"/>
5200 </listOfReactants>
5201 <listOfProducts>
5202 <speciesReference species="M_ahcys_c" stoichiometry="1.000000"/>
5203 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
5204 <speciesReference species="M_q8h2_c" stoichiometry="1.000000"/>
5205 </listOfProducts>
5206 </reaction>
5207 <reaction id="R_DMSOR1" name="R_Dimethyl_sulfoxide_reductase__Menaquinol_8_" reversible="false">
5208 <notes>
5209 <html:p>GENE_ASSOCIATION: ( b0894 and b0895 and b0896 )</html:p>
5210 <html:p>PROTEIN_ASSOCIATION: DmsABC</html:p>
5211 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
5212 <html:p>PROTEIN_CLASS: </html:p>
5213 </notes>
5214 <listOfReactants>
5215 <speciesReference species="M_dmso_c" stoichiometry="1.000000"/>
5216 <speciesReference species="M_mql8_c" stoichiometry="1.000000"/>
5217 </listOfReactants>
5218 <listOfProducts>
5219 <speciesReference species="M_dms_c" stoichiometry="1.000000"/>
5220 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
5221 <speciesReference species="M_mqn8_c" stoichiometry="1.000000"/>
5222 </listOfProducts>
5223 </reaction>
5224 <reaction id="R_DMSOR1e" name="R_Dimethyl_sulfoxide_reductase__Menaquinol_8_" reversible="false">
5225 <notes>
5226 <html:p>GENE_ASSOCIATION: ( b1873 and b1872 )</html:p>
5227 <html:p>PROTEIN_ASSOCIATION: ( TorY and TorZ )</html:p>
5228 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
5229 <html:p>PROTEIN_CLASS: </html:p>
5230 </notes>
5231 <listOfReactants>
5232 <speciesReference species="M_mql8_c" stoichiometry="1.000000"/>
5233 <speciesReference species="M_dmso_e" stoichiometry="1.000000"/>
5234 </listOfReactants>
5235 <listOfProducts>
5236 <speciesReference species="M_mqn8_c" stoichiometry="1.000000"/>
5237 <speciesReference species="M_dms_e" stoichiometry="1.000000"/>
5238 <speciesReference species="M_h2o_e" stoichiometry="1.000000"/>
5239 </listOfProducts>
5240 </reaction>
5241 <reaction id="R_DMSOR2" name="R_Dimethyl_sulfoxide_reductase__Demethylmenaquinol_8_" reversible="false">
5242 <notes>
5243 <html:p>GENE_ASSOCIATION: ( b0894 and b0895 and b0896 )</html:p>
5244 <html:p>PROTEIN_ASSOCIATION: DmsABC</html:p>
5245 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
5246 <html:p>PROTEIN_CLASS: </html:p>
5247 </notes>
5248 <listOfReactants>
5249 <speciesReference species="M_2dmmql8_c" stoichiometry="1.000000"/>
5250 <speciesReference species="M_dmso_c" stoichiometry="1.000000"/>
5251 </listOfReactants>
5252 <listOfProducts>
5253 <speciesReference species="M_2dmmq8_c" stoichiometry="1.000000"/>
5254 <speciesReference species="M_dms_c" stoichiometry="1.000000"/>
5255 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
5256 </listOfProducts>
5257 </reaction>
5258 <reaction id="R_DMSOR2e" name="R_Dimethyl_sulfoxide_reductase__Demethylmenaquinol_8_" reversible="false">
5259 <notes>
5260 <html:p>GENE_ASSOCIATION: ( b1873 and b1872 )</html:p>
5261 <html:p>PROTEIN_ASSOCIATION: ( TorY and TorZ )</html:p>
5262 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
5263 <html:p>PROTEIN_CLASS: </html:p>
5264 </notes>
5265 <listOfReactants>
5266 <speciesReference species="M_2dmmql8_c" stoichiometry="1.000000"/>
5267 <speciesReference species="M_dmso_e" stoichiometry="1.000000"/>
5268 </listOfReactants>
5269 <listOfProducts>
5270 <speciesReference species="M_2dmmq8_c" stoichiometry="1.000000"/>
5271 <speciesReference species="M_dms_e" stoichiometry="1.000000"/>
5272 <speciesReference species="M_h2o_e" stoichiometry="1.000000"/>
5273 </listOfProducts>
5274 </reaction>
5275 <reaction id="R_DNMPPA" name="R_Dihydroneopterin_monophosphate_dephosphorylase" reversible="false">
5276 <notes>
5277 <html:p>GENE_ASSOCIATION: </html:p>
5278 <html:p>PROTEIN_ASSOCIATION: </html:p>
5279 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
5280 <html:p>PROTEIN_CLASS: </html:p>
5281 </notes>
5282 <listOfReactants>
5283 <speciesReference species="M_dhpmp_c" stoichiometry="1.000000"/>
5284 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
5285 </listOfReactants>
5286 <listOfProducts>
5287 <speciesReference species="M_dhnpt_c" stoichiometry="1.000000"/>
5288 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
5289 </listOfProducts>
5290 </reaction>
5291 <reaction id="R_DNTPPA" name="R_Dihydroneopterin_triphosphate_pyrophosphatase" reversible="false">
5292 <notes>
5293 <html:p>GENE_ASSOCIATION: ( b1865 or b0099 )</html:p>
5294 <html:p>PROTEIN_ASSOCIATION: ( NtpA ) or ( MutT )</html:p>
5295 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
5296 <html:p>PROTEIN_CLASS: </html:p>
5297 </notes>
5298 <listOfReactants>
5299 <speciesReference species="M_ahdt_c" stoichiometry="1.000000"/>
5300 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
5301 </listOfReactants>
5302 <listOfProducts>
5303 <speciesReference species="M_dhpmp_c" stoichiometry="1.000000"/>
5304 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
5305 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
5306 </listOfProducts>
5307 </reaction>
5308 <reaction id="R_DOGULNR" name="R_2_3_dioxo_L_gulonate_reductase" reversible="false">
5309 <notes>
5310 <html:p>GENE_ASSOCIATION: b3575</html:p>
5311 <html:p>PROTEIN_ASSOCIATION: YiaK</html:p>
5312 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
5313 <html:p>PROTEIN_CLASS: </html:p>
5314 </notes>
5315 <listOfReactants>
5316 <speciesReference species="M_23doguln_c" stoichiometry="1.000000"/>
5317 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
5318 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
5319 </listOfReactants>
5320 <listOfProducts>
5321 <speciesReference species="M_3dhguln_c" stoichiometry="1.000000"/>
5322 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
5323 </listOfProducts>
5324 </reaction>
5325 <reaction id="R_DPCOAK" name="R_dephospho_CoA_kinase" reversible="false">
5326 <notes>
5327 <html:p>GENE_ASSOCIATION: </html:p>
5328 <html:p>PROTEIN_ASSOCIATION: </html:p>
5329 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
5330 <html:p>PROTEIN_CLASS: 2.7.1.24</html:p>
5331 </notes>
5332 <listOfReactants>
5333 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
5334 <speciesReference species="M_dpcoa_c" stoichiometry="1.000000"/>
5335 </listOfReactants>
5336 <listOfProducts>
5337 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
5338 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
5339 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
5340 </listOfProducts>
5341 </reaction>
5342 <reaction id="R_DPR" name="R_2_dehydropantoate_2_reductase" reversible="false">
5343 <notes>
5344 <html:p>GENE_ASSOCIATION: ( b0425 or b3774 )</html:p>
5345 <html:p>PROTEIN_ASSOCIATION: ( PanE ) or ( IlvCec )</html:p>
5346 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
5347 <html:p>PROTEIN_CLASS: 1.1.1.169</html:p>
5348 </notes>
5349 <listOfReactants>
5350 <speciesReference species="M_2dhp_c" stoichiometry="1.000000"/>
5351 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
5352 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
5353 </listOfReactants>
5354 <listOfProducts>
5355 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
5356 <speciesReference species="M_pant_R_c" stoichiometry="1.000000"/>
5357 </listOfProducts>
5358 </reaction>
5359 <reaction id="R_DRPA" name="R_deoxyribose_phosphate_aldolase" reversible="false">
5360 <notes>
5361 <html:p>GENE_ASSOCIATION: b4381</html:p>
5362 <html:p>PROTEIN_ASSOCIATION: DeoC</html:p>
5363 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
5364 <html:p>PROTEIN_CLASS: 4.1.2.4</html:p>
5365 </notes>
5366 <listOfReactants>
5367 <speciesReference species="M_2dr5p_c" stoichiometry="1.000000"/>
5368 </listOfReactants>
5369 <listOfProducts>
5370 <speciesReference species="M_acald_c" stoichiometry="1.000000"/>
5371 <speciesReference species="M_g3p_c" stoichiometry="1.000000"/>
5372 </listOfProducts>
5373 </reaction>
5374 <reaction id="R_DSERt2r" name="R_D_serine_transport_via_proton_symport" reversible="true">
5375 <notes>
5376 <html:p>GENE_ASSOCIATION: b4208</html:p>
5377 <html:p>PROTEIN_ASSOCIATION: CycAec</html:p>
5378 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
5379 <html:p>PROTEIN_CLASS: </html:p>
5380 </notes>
5381 <listOfReactants>
5382 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
5383 <speciesReference species="M_ser_D_e" stoichiometry="1.000000"/>
5384 </listOfReactants>
5385 <listOfProducts>
5386 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
5387 <speciesReference species="M_ser_D_c" stoichiometry="1.000000"/>
5388 </listOfProducts>
5389 </reaction>
5390 <reaction id="R_DTMPK" name="R_dTMP_kinase" reversible="true">
5391 <notes>
5392 <html:p>GENE_ASSOCIATION: b1098</html:p>
5393 <html:p>PROTEIN_ASSOCIATION: Tmk</html:p>
5394 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
5395 <html:p>PROTEIN_CLASS: 2.7.4.9</html:p>
5396 </notes>
5397 <listOfReactants>
5398 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
5399 <speciesReference species="M_dtmp_c" stoichiometry="1.000000"/>
5400 </listOfReactants>
5401 <listOfProducts>
5402 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
5403 <speciesReference species="M_dtdp_c" stoichiometry="1.000000"/>
5404 </listOfProducts>
5405 </reaction>
5406 <reaction id="R_DURIK1" name="R_deoxyuridine_kinase__ATPDeoxyuridine_" reversible="false">
5407 <notes>
5408 <html:p>GENE_ASSOCIATION: b1238</html:p>
5409 <html:p>PROTEIN_ASSOCIATION: Tdk</html:p>
5410 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
5411 <html:p>PROTEIN_CLASS: </html:p>
5412 </notes>
5413 <listOfReactants>
5414 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
5415 <speciesReference species="M_duri_c" stoichiometry="1.000000"/>
5416 </listOfReactants>
5417 <listOfProducts>
5418 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
5419 <speciesReference species="M_dump_c" stoichiometry="1.000000"/>
5420 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
5421 </listOfProducts>
5422 </reaction>
5423 <reaction id="R_DURIPP" name="R_deoxyuridine_phosphorylase" reversible="true">
5424 <notes>
5425 <html:p>GENE_ASSOCIATION: ( b4382 or b4384 )</html:p>
5426 <html:p>PROTEIN_ASSOCIATION: ( DeoA ) or ( DeoD )</html:p>
5427 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
5428 <html:p>PROTEIN_CLASS: </html:p>
5429 </notes>
5430 <listOfReactants>
5431 <speciesReference species="M_duri_c" stoichiometry="1.000000"/>
5432 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
5433 </listOfReactants>
5434 <listOfProducts>
5435 <speciesReference species="M_2dr1p_c" stoichiometry="1.000000"/>
5436 <speciesReference species="M_ura_c" stoichiometry="1.000000"/>
5437 </listOfProducts>
5438 </reaction>
5439 <reaction id="R_DURIt2" name="R_deoxyuridine_transport_in_via_proton_symport" reversible="false">
5440 <notes>
5441 <html:p>GENE_ASSOCIATION: ( b2964 or b2393 )</html:p>
5442 <html:p>PROTEIN_ASSOCIATION: ( NupG ) or ( NupCec )</html:p>
5443 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
5444 <html:p>PROTEIN_CLASS: </html:p>
5445 </notes>
5446 <listOfReactants>
5447 <speciesReference species="M_duri_e" stoichiometry="1.000000"/>
5448 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
5449 </listOfReactants>
5450 <listOfProducts>
5451 <speciesReference species="M_duri_c" stoichiometry="1.000000"/>
5452 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
5453 </listOfProducts>
5454 </reaction>
5455 <reaction id="R_DUTPDP" name="R_dUTP_diphosphatase" reversible="false">
5456 <notes>
5457 <html:p>GENE_ASSOCIATION: b3640</html:p>
5458 <html:p>PROTEIN_ASSOCIATION: Dutec</html:p>
5459 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
5460 <html:p>PROTEIN_CLASS: 3.6.1.23</html:p>
5461 </notes>
5462 <listOfReactants>
5463 <speciesReference species="M_dutp_c" stoichiometry="1.000000"/>
5464 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
5465 </listOfReactants>
5466 <listOfProducts>
5467 <speciesReference species="M_dump_c" stoichiometry="1.000000"/>
5468 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
5469 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
5470 </listOfProducts>
5471 </reaction>
5472 <reaction id="R_DXPRIi" name="R_1_deoxy_D_xylulose_reductoisomerase" reversible="false">
5473 <notes>
5474 <html:p>GENE_ASSOCIATION: b0173</html:p>
5475 <html:p>PROTEIN_ASSOCIATION: Dxr</html:p>
5476 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
5477 <html:p>PROTEIN_CLASS: </html:p>
5478 </notes>
5479 <listOfReactants>
5480 <speciesReference species="M_dxyl5p_c" stoichiometry="1.000000"/>
5481 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
5482 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
5483 </listOfReactants>
5484 <listOfProducts>
5485 <speciesReference species="M_2me4p_c" stoichiometry="1.000000"/>
5486 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
5487 </listOfProducts>
5488 </reaction>
5489 <reaction id="R_DXPS" name="R_1_deoxy_D_xylulose_5_phosphate_synthase" reversible="false">
5490 <notes>
5491 <html:p>GENE_ASSOCIATION: b0420</html:p>
5492 <html:p>PROTEIN_ASSOCIATION: Dxs</html:p>
5493 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
5494 <html:p>PROTEIN_CLASS: </html:p>
5495 </notes>
5496 <listOfReactants>
5497 <speciesReference species="M_g3p_c" stoichiometry="1.000000"/>
5498 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
5499 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
5500 </listOfReactants>
5501 <listOfProducts>
5502 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
5503 <speciesReference species="M_dxyl5p_c" stoichiometry="1.000000"/>
5504 </listOfProducts>
5505 </reaction>
5506 <reaction id="R_DXYLK" name="R_1_Deoxy_D_xylulose_kinase" reversible="false">
5507 <notes>
5508 <html:p>GENE_ASSOCIATION: b3564</html:p>
5509 <html:p>PROTEIN_ASSOCIATION: XylB</html:p>
5510 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
5511 <html:p>PROTEIN_CLASS: </html:p>
5512 </notes>
5513 <listOfReactants>
5514 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
5515 <speciesReference species="M_dxyl_c" stoichiometry="1.000000"/>
5516 </listOfReactants>
5517 <listOfProducts>
5518 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
5519 <speciesReference species="M_dxyl5p_c" stoichiometry="1.000000"/>
5520 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
5521 </listOfProducts>
5522 </reaction>
5523 <reaction id="R_D_LACt2" name="R_D_lactate_transport_via_proton_symport" reversible="true">
5524 <notes>
5525 <html:p>GENE_ASSOCIATION: ( b3603 or b2975 )</html:p>
5526 <html:p>PROTEIN_ASSOCIATION: ( LldP ) or ( GlcA )</html:p>
5527 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
5528 <html:p>PROTEIN_CLASS: </html:p>
5529 </notes>
5530 <listOfReactants>
5531 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
5532 <speciesReference species="M_lac_D_e" stoichiometry="1.000000"/>
5533 </listOfReactants>
5534 <listOfProducts>
5535 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
5536 <speciesReference species="M_lac_D_c" stoichiometry="1.000000"/>
5537 </listOfProducts>
5538 </reaction>
5539 <reaction id="R_E4PD" name="R_Erythrose_4_phosphate_dehydrogenase" reversible="true">
5540 <notes>
5541 <html:p>GENE_ASSOCIATION: b2927</html:p>
5542 <html:p>PROTEIN_ASSOCIATION: Epd</html:p>
5543 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
5544 <html:p>PROTEIN_CLASS: </html:p>
5545 </notes>
5546 <listOfReactants>
5547 <speciesReference species="M_e4p_c" stoichiometry="1.000000"/>
5548 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
5549 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
5550 </listOfReactants>
5551 <listOfProducts>
5552 <speciesReference species="M_4per_c" stoichiometry="1.000000"/>
5553 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
5554 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
5555 </listOfProducts>
5556 </reaction>
5557 <reaction id="R_ECAP_EC" name="R_ECA_polymerization__Ecoli_" reversible="false">
5558 <notes>
5559 <html:p>GENE_ASSOCIATION: </html:p>
5560 <html:p>PROTEIN_ASSOCIATION: </html:p>
5561 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
5562 <html:p>PROTEIN_CLASS: </html:p>
5563 </notes>
5564 <listOfReactants>
5565 <speciesReference species="M_unagamuf_c" stoichiometry="1.000000"/>
5566 </listOfReactants>
5567 <listOfProducts>
5568 <speciesReference species="M_eca_EC_c" stoichiometry="1.000000"/>
5569 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
5570 <speciesReference species="M_udcpdp_c" stoichiometry="1.000000"/>
5571 </listOfProducts>
5572 </reaction>
5573 <reaction id="R_EDA" name="R_2_dehydro_3_deoxy_phosphogluconate_aldolase" reversible="false">
5574 <notes>
5575 <html:p>GENE_ASSOCIATION: b1850</html:p>
5576 <html:p>PROTEIN_ASSOCIATION: Eda</html:p>
5577 <html:p>SUBSYSTEM: S_Pentose_Phosphate_Pathway</html:p>
5578 <html:p>PROTEIN_CLASS: 4.1.2.14</html:p>
5579 </notes>
5580 <listOfReactants>
5581 <speciesReference species="M_2ddg6p_c" stoichiometry="1.000000"/>
5582 </listOfReactants>
5583 <listOfProducts>
5584 <speciesReference species="M_g3p_c" stoichiometry="1.000000"/>
5585 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
5586 </listOfProducts>
5587 </reaction>
5588 <reaction id="R_EDD" name="R_6_phosphogluconate_dehydratase" reversible="false">
5589 <notes>
5590 <html:p>GENE_ASSOCIATION: b1851</html:p>
5591 <html:p>PROTEIN_ASSOCIATION: Edd</html:p>
5592 <html:p>SUBSYSTEM: S_Pentose_Phosphate_Pathway</html:p>
5593 <html:p>PROTEIN_CLASS: 4.2.1.12</html:p>
5594 </notes>
5595 <listOfReactants>
5596 <speciesReference species="M_6pgc_c" stoichiometry="1.000000"/>
5597 </listOfReactants>
5598 <listOfProducts>
5599 <speciesReference species="M_2ddg6p_c" stoichiometry="1.000000"/>
5600 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
5601 </listOfProducts>
5602 </reaction>
5603 <reaction id="R_EDTXS1" name="R_Endotoxin_Synthesis__lauroyl_transferase_" reversible="false">
5604 <notes>
5605 <html:p>GENE_ASSOCIATION: b1054</html:p>
5606 <html:p>PROTEIN_ASSOCIATION: LpxL</html:p>
5607 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
5608 <html:p>PROTEIN_CLASS: </html:p>
5609 </notes>
5610 <listOfReactants>
5611 <speciesReference species="M_ddcaACP_c" stoichiometry="1.000000"/>
5612 <speciesReference species="M_kdo2lipid4_c" stoichiometry="1.000000"/>
5613 </listOfReactants>
5614 <listOfProducts>
5615 <speciesReference species="M_ACP_c" stoichiometry="1.000000"/>
5616 <speciesReference species="M_kdo2lipid4L_c" stoichiometry="1.000000"/>
5617 </listOfProducts>
5618 </reaction>
5619 <reaction id="R_EDTXS2" name="R_Endotoxin_Synthesis__myristoyl_transferase_" reversible="false">
5620 <notes>
5621 <html:p>GENE_ASSOCIATION: b1855</html:p>
5622 <html:p>PROTEIN_ASSOCIATION: MsbB</html:p>
5623 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
5624 <html:p>PROTEIN_CLASS: </html:p>
5625 </notes>
5626 <listOfReactants>
5627 <speciesReference species="M_kdo2lipid4L_c" stoichiometry="1.000000"/>
5628 <speciesReference species="M_myrsACP_c" stoichiometry="1.000000"/>
5629 </listOfReactants>
5630 <listOfProducts>
5631 <speciesReference species="M_ACP_c" stoichiometry="1.000000"/>
5632 <speciesReference species="M_lipa_c" stoichiometry="1.000000"/>
5633 </listOfProducts>
5634 </reaction>
5635 <reaction id="R_EDTXS3" name="R_Endotoxin_Synthesis__palmitoleoyl_ACP_" reversible="false">
5636 <notes>
5637 <html:p>GENE_ASSOCIATION: b2378</html:p>
5638 <html:p>PROTEIN_ASSOCIATION: LpxP</html:p>
5639 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
5640 <html:p>PROTEIN_CLASS: </html:p>
5641 </notes>
5642 <listOfReactants>
5643 <speciesReference species="M_hdeACP_c" stoichiometry="1.000000"/>
5644 <speciesReference species="M_kdo2lipid4_c" stoichiometry="1.000000"/>
5645 </listOfReactants>
5646 <listOfProducts>
5647 <speciesReference species="M_ACP_c" stoichiometry="1.000000"/>
5648 <speciesReference species="M_kdo2lipid4p_c" stoichiometry="1.000000"/>
5649 </listOfProducts>
5650 </reaction>
5651 <reaction id="R_EDTXS4" name="R_Endotoxin_Synthesis__myristoyl_transferase_" reversible="false">
5652 <notes>
5653 <html:p>GENE_ASSOCIATION: b1855</html:p>
5654 <html:p>PROTEIN_ASSOCIATION: MsbB</html:p>
5655 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
5656 <html:p>PROTEIN_CLASS: </html:p>
5657 </notes>
5658 <listOfReactants>
5659 <speciesReference species="M_kdo2lipid4p_c" stoichiometry="1.000000"/>
5660 <speciesReference species="M_myrsACP_c" stoichiometry="1.000000"/>
5661 </listOfReactants>
5662 <listOfProducts>
5663 <speciesReference species="M_ACP_c" stoichiometry="1.000000"/>
5664 <speciesReference species="M_lipa_cold_c" stoichiometry="1.000000"/>
5665 </listOfProducts>
5666 </reaction>
5667 <reaction id="R_ENO" name="R_enolase" reversible="true">
5668 <notes>
5669 <html:p>GENE_ASSOCIATION: b2779</html:p>
5670 <html:p>PROTEIN_ASSOCIATION: Eno</html:p>
5671 <html:p>SUBSYSTEM: S_GlycolysisGluconeogenesis</html:p>
5672 <html:p>PROTEIN_CLASS: 4.2.1.11</html:p>
5673 </notes>
5674 <listOfReactants>
5675 <speciesReference species="M_2pg_c" stoichiometry="1.000000"/>
5676 </listOfReactants>
5677 <listOfProducts>
5678 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
5679 <speciesReference species="M_pep_c" stoichiometry="1.000000"/>
5680 </listOfProducts>
5681 </reaction>
5682 <reaction id="R_ENTCS" name="R_enterochelin_synthase" reversible="false">
5683 <notes>
5684 <html:p>GENE_ASSOCIATION: b0583</html:p>
5685 <html:p>PROTEIN_ASSOCIATION: EntD</html:p>
5686 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
5687 <html:p>PROTEIN_CLASS: </html:p>
5688 </notes>
5689 <listOfReactants>
5690 <speciesReference species="M_23dhba_c" stoichiometry="3.000000"/>
5691 <speciesReference species="M_seramp_c" stoichiometry="3.000000"/>
5692 </listOfReactants>
5693 <listOfProducts>
5694 <speciesReference species="M_amp_c" stoichiometry="6.000000"/>
5695 <speciesReference species="M_enter_c" stoichiometry="1.000000"/>
5696 <speciesReference species="M_h_c" stoichiometry="6.000000"/>
5697 </listOfProducts>
5698 </reaction>
5699 <reaction id="R_ETHAAL" name="R_Ethanolamine_ammonia_lyase" reversible="false">
5700 <notes>
5701 <html:p>GENE_ASSOCIATION: ( b2440 and b2441 )</html:p>
5702 <html:p>PROTEIN_ASSOCIATION: EutBC</html:p>
5703 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
5704 <html:p>PROTEIN_CLASS: 4.3.1.7</html:p>
5705 </notes>
5706 <listOfReactants>
5707 <speciesReference species="M_etha_c" stoichiometry="1.000000"/>
5708 </listOfReactants>
5709 <listOfProducts>
5710 <speciesReference species="M_acald_c" stoichiometry="1.000000"/>
5711 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
5712 </listOfProducts>
5713 </reaction>
5714 <reaction id="R_ETOHt2r" name="R_ethanol_reversible_transport_via_proton_symport" reversible="true">
5715 <notes>
5716 <html:p>GENE_ASSOCIATION: </html:p>
5717 <html:p>PROTEIN_ASSOCIATION: </html:p>
5718 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
5719 <html:p>PROTEIN_CLASS: </html:p>
5720 </notes>
5721 <listOfReactants>
5722 <speciesReference species="M_etoh_e" stoichiometry="1.000000"/>
5723 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
5724 </listOfReactants>
5725 <listOfProducts>
5726 <speciesReference species="M_etoh_c" stoichiometry="1.000000"/>
5727 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
5728 </listOfProducts>
5729 </reaction>
5730 <reaction id="R_EX_12ppd_S_e_" name="R__S__Propane_1_2_diol_exchange" reversible="true">
5731 <notes>
5732 <html:p>GENE_ASSOCIATION: </html:p>
5733 <html:p>PROTEIN_ASSOCIATION: </html:p>
5734 <html:p>SUBSYSTEM: S_</html:p>
5735 <html:p>PROTEIN_CLASS: </html:p>
5736 </notes>
5737 <listOfReactants>
5738 <speciesReference species="M_12ppd_S_e" stoichiometry="1.000000"/>
5739 </listOfReactants>
5740 <listOfProducts>
5741 <speciesReference species="M_12ppd_S_b" stoichiometry="1.000000"/>
5742 </listOfProducts>
5743 </reaction>
5744 <reaction id="R_EX_15dap_e_" name="R_1_5_Diaminopentane_exchange" reversible="true">
5745 <notes>
5746 <html:p>GENE_ASSOCIATION: </html:p>
5747 <html:p>PROTEIN_ASSOCIATION: </html:p>
5748 <html:p>SUBSYSTEM: S_</html:p>
5749 <html:p>PROTEIN_CLASS: </html:p>
5750 </notes>
5751 <listOfReactants>
5752 <speciesReference species="M_15dap_e" stoichiometry="1.000000"/>
5753 </listOfReactants>
5754 <listOfProducts>
5755 <speciesReference species="M_15dap_b" stoichiometry="1.000000"/>
5756 </listOfProducts>
5757 </reaction>
5758 <reaction id="R_EX_26dap_M_e_" name="R_meso_2_6_Diaminoheptanedioate_exchange" reversible="true">
5759 <notes>
5760 <html:p>GENE_ASSOCIATION: </html:p>
5761 <html:p>PROTEIN_ASSOCIATION: </html:p>
5762 <html:p>SUBSYSTEM: S_</html:p>
5763 <html:p>PROTEIN_CLASS: </html:p>
5764 </notes>
5765 <listOfReactants>
5766 <speciesReference species="M_26dap_M_e" stoichiometry="1.000000"/>
5767 </listOfReactants>
5768 <listOfProducts>
5769 <speciesReference species="M_26dap_M_b" stoichiometry="1.000000"/>
5770 </listOfProducts>
5771 </reaction>
5772 <reaction id="R_EX_2ddglcn_e_" name="R_2_Dehydro_3_deoxy_D_gluconate_exchange" reversible="true">
5773 <notes>
5774 <html:p>GENE_ASSOCIATION: </html:p>
5775 <html:p>PROTEIN_ASSOCIATION: </html:p>
5776 <html:p>SUBSYSTEM: S_</html:p>
5777 <html:p>PROTEIN_CLASS: </html:p>
5778 </notes>
5779 <listOfReactants>
5780 <speciesReference species="M_2ddglcn_e" stoichiometry="1.000000"/>
5781 </listOfReactants>
5782 <listOfProducts>
5783 <speciesReference species="M_2ddglcn_b" stoichiometry="1.000000"/>
5784 </listOfProducts>
5785 </reaction>
5786 <reaction id="R_EX_3hcinnm_e_" name="R_3_hydroxycinnamic_acid_exchange" reversible="true">
5787 <notes>
5788 <html:p>GENE_ASSOCIATION: </html:p>
5789 <html:p>PROTEIN_ASSOCIATION: </html:p>
5790 <html:p>SUBSYSTEM: S_</html:p>
5791 <html:p>PROTEIN_CLASS: </html:p>
5792 </notes>
5793 <listOfReactants>
5794 <speciesReference species="M_3hcinnm_e" stoichiometry="1.000000"/>
5795 </listOfReactants>
5796 <listOfProducts>
5797 <speciesReference species="M_3hcinnm_b" stoichiometry="1.000000"/>
5798 </listOfProducts>
5799 </reaction>
5800 <reaction id="R_EX_3hpppn_e_" name="R_3__3_hydroxy_phenyl_propionate_exchange" reversible="true">
5801 <notes>
5802 <html:p>GENE_ASSOCIATION: </html:p>
5803 <html:p>PROTEIN_ASSOCIATION: </html:p>
5804 <html:p>SUBSYSTEM: S_</html:p>
5805 <html:p>PROTEIN_CLASS: </html:p>
5806 </notes>
5807 <listOfReactants>
5808 <speciesReference species="M_3hpppn_e" stoichiometry="1.000000"/>
5809 </listOfReactants>
5810 <listOfProducts>
5811 <speciesReference species="M_3hpppn_b" stoichiometry="1.000000"/>
5812 </listOfProducts>
5813 </reaction>
5814 <reaction id="R_EX_4abut_e_" name="R_4_Aminobutanoate_exchange" reversible="true">
5815 <notes>
5816 <html:p>GENE_ASSOCIATION: </html:p>
5817 <html:p>PROTEIN_ASSOCIATION: </html:p>
5818 <html:p>SUBSYSTEM: S_</html:p>
5819 <html:p>PROTEIN_CLASS: </html:p>
5820 </notes>
5821 <listOfReactants>
5822 <speciesReference species="M_4abut_e" stoichiometry="1.000000"/>
5823 </listOfReactants>
5824 <listOfProducts>
5825 <speciesReference species="M_4abut_b" stoichiometry="1.000000"/>
5826 </listOfProducts>
5827 </reaction>
5828 <reaction id="R_EX_ac_e_" name="R_Acetate_exchange" reversible="true">
5829 <notes>
5830 <html:p>GENE_ASSOCIATION: </html:p>
5831 <html:p>PROTEIN_ASSOCIATION: </html:p>
5832 <html:p>SUBSYSTEM: S_</html:p>
5833 <html:p>PROTEIN_CLASS: </html:p>
5834 </notes>
5835 <listOfReactants>
5836 <speciesReference species="M_ac_e" stoichiometry="1.000000"/>
5837 </listOfReactants>
5838 <listOfProducts>
5839 <speciesReference species="M_ac_b" stoichiometry="1.000000"/>
5840 </listOfProducts>
5841 </reaction>
5842 <reaction id="R_EX_acac_e_" name="R_Acetoacetate_exchange" reversible="true">
5843 <notes>
5844 <html:p>GENE_ASSOCIATION: </html:p>
5845 <html:p>PROTEIN_ASSOCIATION: </html:p>
5846 <html:p>SUBSYSTEM: S_</html:p>
5847 <html:p>PROTEIN_CLASS: </html:p>
5848 </notes>
5849 <listOfReactants>
5850 <speciesReference species="M_acac_e" stoichiometry="1.000000"/>
5851 </listOfReactants>
5852 <listOfProducts>
5853 <speciesReference species="M_acac_b" stoichiometry="1.000000"/>
5854 </listOfProducts>
5855 </reaction>
5856 <reaction id="R_EX_acald_e_" name="R_Acetaldehyde_exchange" reversible="true">
5857 <notes>
5858 <html:p>GENE_ASSOCIATION: </html:p>
5859 <html:p>PROTEIN_ASSOCIATION: </html:p>
5860 <html:p>SUBSYSTEM: S_</html:p>
5861 <html:p>PROTEIN_CLASS: </html:p>
5862 </notes>
5863 <listOfReactants>
5864 <speciesReference species="M_acald_e" stoichiometry="1.000000"/>
5865 </listOfReactants>
5866 <listOfProducts>
5867 <speciesReference species="M_acald_b" stoichiometry="1.000000"/>
5868 </listOfProducts>
5869 </reaction>
5870 <reaction id="R_EX_acgam_e_" name="R_N_Acetyl_D_glucosamine_exchange" reversible="true">
5871 <notes>
5872 <html:p>GENE_ASSOCIATION: </html:p>
5873 <html:p>PROTEIN_ASSOCIATION: </html:p>
5874 <html:p>SUBSYSTEM: S_</html:p>
5875 <html:p>PROTEIN_CLASS: </html:p>
5876 </notes>
5877 <listOfReactants>
5878 <speciesReference species="M_acgam_e" stoichiometry="1.000000"/>
5879 </listOfReactants>
5880 <listOfProducts>
5881 <speciesReference species="M_acgam_b" stoichiometry="1.000000"/>
5882 </listOfProducts>
5883 </reaction>
5884 <reaction id="R_EX_acmana_e_" name="R_N_Acetyl_D_mannosamine_exchange" reversible="true">
5885 <notes>
5886 <html:p>GENE_ASSOCIATION: </html:p>
5887 <html:p>PROTEIN_ASSOCIATION: </html:p>
5888 <html:p>SUBSYSTEM: S_</html:p>
5889 <html:p>PROTEIN_CLASS: </html:p>
5890 </notes>
5891 <listOfReactants>
5892 <speciesReference species="M_acmana_e" stoichiometry="1.000000"/>
5893 </listOfReactants>
5894 <listOfProducts>
5895 <speciesReference species="M_acmana_b" stoichiometry="1.000000"/>
5896 </listOfProducts>
5897 </reaction>
5898 <reaction id="R_EX_acnam_e_" name="R_N_Acetylneuraminate_exchange" reversible="true">
5899 <notes>
5900 <html:p>GENE_ASSOCIATION: </html:p>
5901 <html:p>PROTEIN_ASSOCIATION: </html:p>
5902 <html:p>SUBSYSTEM: S_</html:p>
5903 <html:p>PROTEIN_CLASS: </html:p>
5904 </notes>
5905 <listOfReactants>
5906 <speciesReference species="M_acnam_e" stoichiometry="1.000000"/>
5907 </listOfReactants>
5908 <listOfProducts>
5909 <speciesReference species="M_acnam_b" stoichiometry="1.000000"/>
5910 </listOfProducts>
5911 </reaction>
5912 <reaction id="R_EX_ade_e_" name="R_Adenine_exchange" reversible="true">
5913 <notes>
5914 <html:p>GENE_ASSOCIATION: </html:p>
5915 <html:p>PROTEIN_ASSOCIATION: </html:p>
5916 <html:p>SUBSYSTEM: S_</html:p>
5917 <html:p>PROTEIN_CLASS: </html:p>
5918 </notes>
5919 <listOfReactants>
5920 <speciesReference species="M_ade_e" stoichiometry="1.000000"/>
5921 </listOfReactants>
5922 <listOfProducts>
5923 <speciesReference species="M_ade_b" stoichiometry="1.000000"/>
5924 </listOfProducts>
5925 </reaction>
5926 <reaction id="R_EX_adn_e_" name="R_Adenosine_exchange" reversible="true">
5927 <notes>
5928 <html:p>GENE_ASSOCIATION: </html:p>
5929 <html:p>PROTEIN_ASSOCIATION: </html:p>
5930 <html:p>SUBSYSTEM: S_</html:p>
5931 <html:p>PROTEIN_CLASS: </html:p>
5932 </notes>
5933 <listOfReactants>
5934 <speciesReference species="M_adn_e" stoichiometry="1.000000"/>
5935 </listOfReactants>
5936 <listOfProducts>
5937 <speciesReference species="M_adn_b" stoichiometry="1.000000"/>
5938 </listOfProducts>
5939 </reaction>
5940 <reaction id="R_EX_akg_e_" name="R_2_Oxoglutarate_exchange" reversible="true">
5941 <notes>
5942 <html:p>GENE_ASSOCIATION: </html:p>
5943 <html:p>PROTEIN_ASSOCIATION: </html:p>
5944 <html:p>SUBSYSTEM: S_</html:p>
5945 <html:p>PROTEIN_CLASS: </html:p>
5946 </notes>
5947 <listOfReactants>
5948 <speciesReference species="M_akg_e" stoichiometry="1.000000"/>
5949 </listOfReactants>
5950 <listOfProducts>
5951 <speciesReference species="M_akg_b" stoichiometry="1.000000"/>
5952 </listOfProducts>
5953 </reaction>
5954 <reaction id="R_EX_ala_D_e_" name="R_D_Alanine_exchange" reversible="true">
5955 <notes>
5956 <html:p>GENE_ASSOCIATION: </html:p>
5957 <html:p>PROTEIN_ASSOCIATION: </html:p>
5958 <html:p>SUBSYSTEM: S_</html:p>
5959 <html:p>PROTEIN_CLASS: </html:p>
5960 </notes>
5961 <listOfReactants>
5962 <speciesReference species="M_ala_D_e" stoichiometry="1.000000"/>
5963 </listOfReactants>
5964 <listOfProducts>
5965 <speciesReference species="M_ala_D_b" stoichiometry="1.000000"/>
5966 </listOfProducts>
5967 </reaction>
5968 <reaction id="R_EX_ala_L_e_" name="R_L_Alanine_exchange" reversible="true">
5969 <notes>
5970 <html:p>GENE_ASSOCIATION: </html:p>
5971 <html:p>PROTEIN_ASSOCIATION: </html:p>
5972 <html:p>SUBSYSTEM: S_</html:p>
5973 <html:p>PROTEIN_CLASS: </html:p>
5974 </notes>
5975 <listOfReactants>
5976 <speciesReference species="M_ala_L_e" stoichiometry="1.000000"/>
5977 </listOfReactants>
5978 <listOfProducts>
5979 <speciesReference species="M_ala_L_b" stoichiometry="1.000000"/>
5980 </listOfProducts>
5981 </reaction>
5982 <reaction id="R_EX_alltn_e_" name="R_Allantoin_exchange" reversible="true">
5983 <notes>
5984 <html:p>GENE_ASSOCIATION: </html:p>
5985 <html:p>PROTEIN_ASSOCIATION: </html:p>
5986 <html:p>SUBSYSTEM: S_</html:p>
5987 <html:p>PROTEIN_CLASS: </html:p>
5988 </notes>
5989 <listOfReactants>
5990 <speciesReference species="M_alltn_e" stoichiometry="1.000000"/>
5991 </listOfReactants>
5992 <listOfProducts>
5993 <speciesReference species="M_alltn_b" stoichiometry="1.000000"/>
5994 </listOfProducts>
5995 </reaction>
5996 <reaction id="R_EX_amp_e_" name="R_AMP_exchange" reversible="true">
5997 <notes>
5998 <html:p>GENE_ASSOCIATION: </html:p>
5999 <html:p>PROTEIN_ASSOCIATION: </html:p>
6000 <html:p>SUBSYSTEM: S_</html:p>
6001 <html:p>PROTEIN_CLASS: </html:p>
6002 </notes>
6003 <listOfReactants>
6004 <speciesReference species="M_amp_e" stoichiometry="1.000000"/>
6005 </listOfReactants>
6006 <listOfProducts>
6007 <speciesReference species="M_amp_b" stoichiometry="1.000000"/>
6008 </listOfProducts>
6009 </reaction>
6010 <reaction id="R_EX_arab_L_e_" name="R_L_Arabinose_exchange" reversible="true">
6011 <notes>
6012 <html:p>GENE_ASSOCIATION: </html:p>
6013 <html:p>PROTEIN_ASSOCIATION: </html:p>
6014 <html:p>SUBSYSTEM: S_</html:p>
6015 <html:p>PROTEIN_CLASS: </html:p>
6016 </notes>
6017 <listOfReactants>
6018 <speciesReference species="M_arab_L_e" stoichiometry="1.000000"/>
6019 </listOfReactants>
6020 <listOfProducts>
6021 <speciesReference species="M_arab_L_b" stoichiometry="1.000000"/>
6022 </listOfProducts>
6023 </reaction>
6024 <reaction id="R_EX_arg_L_e_" name="R_L_Arginine_exchange" reversible="true">
6025 <notes>
6026 <html:p>GENE_ASSOCIATION: </html:p>
6027 <html:p>PROTEIN_ASSOCIATION: </html:p>
6028 <html:p>SUBSYSTEM: S_</html:p>
6029 <html:p>PROTEIN_CLASS: </html:p>
6030 </notes>
6031 <listOfReactants>
6032 <speciesReference species="M_arg_L_e" stoichiometry="1.000000"/>
6033 </listOfReactants>
6034 <listOfProducts>
6035 <speciesReference species="M_arg_L_b" stoichiometry="1.000000"/>
6036 </listOfProducts>
6037 </reaction>
6038 <reaction id="R_EX_asn_L_e_" name="R_L_Asparagine_exchange" reversible="true">
6039 <notes>
6040 <html:p>GENE_ASSOCIATION: </html:p>
6041 <html:p>PROTEIN_ASSOCIATION: </html:p>
6042 <html:p>SUBSYSTEM: S_</html:p>
6043 <html:p>PROTEIN_CLASS: </html:p>
6044 </notes>
6045 <listOfReactants>
6046 <speciesReference species="M_asn_L_e" stoichiometry="1.000000"/>
6047 </listOfReactants>
6048 <listOfProducts>
6049 <speciesReference species="M_asn_L_b" stoichiometry="1.000000"/>
6050 </listOfProducts>
6051 </reaction>
6052 <reaction id="R_EX_asp_L_e_" name="R_L_Aspartate_exchange" reversible="true">
6053 <notes>
6054 <html:p>GENE_ASSOCIATION: </html:p>
6055 <html:p>PROTEIN_ASSOCIATION: </html:p>
6056 <html:p>SUBSYSTEM: S_</html:p>
6057 <html:p>PROTEIN_CLASS: </html:p>
6058 </notes>
6059 <listOfReactants>
6060 <speciesReference species="M_asp_L_e" stoichiometry="1.000000"/>
6061 </listOfReactants>
6062 <listOfProducts>
6063 <speciesReference species="M_asp_L_b" stoichiometry="1.000000"/>
6064 </listOfProducts>
6065 </reaction>
6066 <reaction id="R_EX_but_e_" name="R_Butyrate__n_C40__exchange" reversible="true">
6067 <notes>
6068 <html:p>GENE_ASSOCIATION: </html:p>
6069 <html:p>PROTEIN_ASSOCIATION: </html:p>
6070 <html:p>SUBSYSTEM: S_</html:p>
6071 <html:p>PROTEIN_CLASS: </html:p>
6072 </notes>
6073 <listOfReactants>
6074 <speciesReference species="M_but_e" stoichiometry="1.000000"/>
6075 </listOfReactants>
6076 <listOfProducts>
6077 <speciesReference species="M_but_b" stoichiometry="1.000000"/>
6078 </listOfProducts>
6079 </reaction>
6080 <reaction id="R_EX_cbl1_e_" name="R_Cob_I_alamin_exchange" reversible="true">
6081 <notes>
6082 <html:p>GENE_ASSOCIATION: </html:p>
6083 <html:p>PROTEIN_ASSOCIATION: </html:p>
6084 <html:p>SUBSYSTEM: S_</html:p>
6085 <html:p>PROTEIN_CLASS: </html:p>
6086 </notes>
6087 <listOfReactants>
6088 <speciesReference species="M_cbl1_e" stoichiometry="1.000000"/>
6089 </listOfReactants>
6090 <listOfProducts>
6091 <speciesReference species="M_cbl1_b" stoichiometry="1.000000"/>
6092 </listOfProducts>
6093 </reaction>
6094 <reaction id="R_EX_chol_e_" name="R_Choline_exchange" reversible="true">
6095 <notes>
6096 <html:p>GENE_ASSOCIATION: </html:p>
6097 <html:p>PROTEIN_ASSOCIATION: </html:p>
6098 <html:p>SUBSYSTEM: S_</html:p>
6099 <html:p>PROTEIN_CLASS: </html:p>
6100 </notes>
6101 <listOfReactants>
6102 <speciesReference species="M_chol_e" stoichiometry="1.000000"/>
6103 </listOfReactants>
6104 <listOfProducts>
6105 <speciesReference species="M_chol_b" stoichiometry="1.000000"/>
6106 </listOfProducts>
6107 </reaction>
6108 <reaction id="R_EX_cit_e_" name="R_Citrate_exchange" reversible="true">
6109 <notes>
6110 <html:p>GENE_ASSOCIATION: </html:p>
6111 <html:p>PROTEIN_ASSOCIATION: </html:p>
6112 <html:p>SUBSYSTEM: S_</html:p>
6113 <html:p>PROTEIN_CLASS: </html:p>
6114 </notes>
6115 <listOfReactants>
6116 <speciesReference species="M_cit_e" stoichiometry="1.000000"/>
6117 </listOfReactants>
6118 <listOfProducts>
6119 <speciesReference species="M_cit_b" stoichiometry="1.000000"/>
6120 </listOfProducts>
6121 </reaction>
6122 <reaction id="R_EX_co2_e_" name="R_CO2_exchange" reversible="true">
6123 <notes>
6124 <html:p>GENE_ASSOCIATION: </html:p>
6125 <html:p>PROTEIN_ASSOCIATION: </html:p>
6126 <html:p>SUBSYSTEM: S_</html:p>
6127 <html:p>PROTEIN_CLASS: </html:p>
6128 </notes>
6129 <listOfReactants>
6130 <speciesReference species="M_co2_e" stoichiometry="1.000000"/>
6131 </listOfReactants>
6132 <listOfProducts>
6133 <speciesReference species="M_co2_b" stoichiometry="1.000000"/>
6134 </listOfProducts>
6135 </reaction>
6136 <reaction id="R_EX_crn_e_" name="R_L_Carnitine_exchange" reversible="true">
6137 <notes>
6138 <html:p>GENE_ASSOCIATION: </html:p>
6139 <html:p>PROTEIN_ASSOCIATION: </html:p>
6140 <html:p>SUBSYSTEM: S_</html:p>
6141 <html:p>PROTEIN_CLASS: </html:p>
6142 </notes>
6143 <listOfReactants>
6144 <speciesReference species="M_crn_e" stoichiometry="1.000000"/>
6145 </listOfReactants>
6146 <listOfProducts>
6147 <speciesReference species="M_crn_b" stoichiometry="1.000000"/>
6148 </listOfProducts>
6149 </reaction>
6150 <reaction id="R_EX_csn_e_" name="R_Cytosine_exchange" reversible="true">
6151 <notes>
6152 <html:p>GENE_ASSOCIATION: </html:p>
6153 <html:p>PROTEIN_ASSOCIATION: </html:p>
6154 <html:p>SUBSYSTEM: S_</html:p>
6155 <html:p>PROTEIN_CLASS: </html:p>
6156 </notes>
6157 <listOfReactants>
6158 <speciesReference species="M_csn_e" stoichiometry="1.000000"/>
6159 </listOfReactants>
6160 <listOfProducts>
6161 <speciesReference species="M_csn_b" stoichiometry="1.000000"/>
6162 </listOfProducts>
6163 </reaction>
6164 <reaction id="R_EX_cynt_e_" name="R_Cyanate_exchange" reversible="true">
6165 <notes>
6166 <html:p>GENE_ASSOCIATION: </html:p>
6167 <html:p>PROTEIN_ASSOCIATION: </html:p>
6168 <html:p>SUBSYSTEM: S_</html:p>
6169 <html:p>PROTEIN_CLASS: </html:p>
6170 </notes>
6171 <listOfReactants>
6172 <speciesReference species="M_cynt_e" stoichiometry="1.000000"/>
6173 </listOfReactants>
6174 <listOfProducts>
6175 <speciesReference species="M_cynt_b" stoichiometry="1.000000"/>
6176 </listOfProducts>
6177 </reaction>
6178 <reaction id="R_EX_cys_L_e_" name="R_L_Cysteine_exchange" reversible="true">
6179 <notes>
6180 <html:p>GENE_ASSOCIATION: </html:p>
6181 <html:p>PROTEIN_ASSOCIATION: </html:p>
6182 <html:p>SUBSYSTEM: S_</html:p>
6183 <html:p>PROTEIN_CLASS: </html:p>
6184 </notes>
6185 <listOfReactants>
6186 <speciesReference species="M_cys_L_e" stoichiometry="1.000000"/>
6187 </listOfReactants>
6188 <listOfProducts>
6189 <speciesReference species="M_cys_L_b" stoichiometry="1.000000"/>
6190 </listOfProducts>
6191 </reaction>
6192 <reaction id="R_EX_cytd_e_" name="R_Cytidine_exchange" reversible="true">
6193 <notes>
6194 <html:p>GENE_ASSOCIATION: </html:p>
6195 <html:p>PROTEIN_ASSOCIATION: </html:p>
6196 <html:p>SUBSYSTEM: S_</html:p>
6197 <html:p>PROTEIN_CLASS: </html:p>
6198 </notes>
6199 <listOfReactants>
6200 <speciesReference species="M_cytd_e" stoichiometry="1.000000"/>
6201 </listOfReactants>
6202 <listOfProducts>
6203 <speciesReference species="M_cytd_b" stoichiometry="1.000000"/>
6204 </listOfProducts>
6205 </reaction>
6206 <reaction id="R_EX_dad_2_e_" name="R_Deoxyadenosine_exchange" reversible="true">
6207 <notes>
6208 <html:p>GENE_ASSOCIATION: </html:p>
6209 <html:p>PROTEIN_ASSOCIATION: </html:p>
6210 <html:p>SUBSYSTEM: S_</html:p>
6211 <html:p>PROTEIN_CLASS: </html:p>
6212 </notes>
6213 <listOfReactants>
6214 <speciesReference species="M_dad_2_e" stoichiometry="1.000000"/>
6215 </listOfReactants>
6216 <listOfProducts>
6217 <speciesReference species="M_dad_2_b" stoichiometry="1.000000"/>
6218 </listOfProducts>
6219 </reaction>
6220 <reaction id="R_EX_dcyt_e_" name="R_Deoxycytidine_exchange" reversible="true">
6221 <notes>
6222 <html:p>GENE_ASSOCIATION: </html:p>
6223 <html:p>PROTEIN_ASSOCIATION: </html:p>
6224 <html:p>SUBSYSTEM: S_</html:p>
6225 <html:p>PROTEIN_CLASS: </html:p>
6226 </notes>
6227 <listOfReactants>
6228 <speciesReference species="M_dcyt_e" stoichiometry="1.000000"/>
6229 </listOfReactants>
6230 <listOfProducts>
6231 <speciesReference species="M_dcyt_b" stoichiometry="1.000000"/>
6232 </listOfProducts>
6233 </reaction>
6234 <reaction id="R_EX_dgsn_e_" name="R_Deoxyguanosine_exchange" reversible="true">
6235 <notes>
6236 <html:p>GENE_ASSOCIATION: </html:p>
6237 <html:p>PROTEIN_ASSOCIATION: </html:p>
6238 <html:p>SUBSYSTEM: S_</html:p>
6239 <html:p>PROTEIN_CLASS: </html:p>
6240 </notes>
6241 <listOfReactants>
6242 <speciesReference species="M_dgsn_e" stoichiometry="1.000000"/>
6243 </listOfReactants>
6244 <listOfProducts>
6245 <speciesReference species="M_dgsn_b" stoichiometry="1.000000"/>
6246 </listOfProducts>
6247 </reaction>
6248 <reaction id="R_EX_dha_e_" name="R_Dihydroxyacetone_exchange" reversible="true">
6249 <notes>
6250 <html:p>GENE_ASSOCIATION: </html:p>
6251 <html:p>PROTEIN_ASSOCIATION: </html:p>
6252 <html:p>SUBSYSTEM: S_</html:p>
6253 <html:p>PROTEIN_CLASS: </html:p>
6254 </notes>
6255 <listOfReactants>
6256 <speciesReference species="M_dha_e" stoichiometry="1.000000"/>
6257 </listOfReactants>
6258 <listOfProducts>
6259 <speciesReference species="M_dha_b" stoichiometry="1.000000"/>
6260 </listOfProducts>
6261 </reaction>
6262 <reaction id="R_EX_din_e_" name="R_Deoxyinosine_exchange" reversible="true">
6263 <notes>
6264 <html:p>GENE_ASSOCIATION: </html:p>
6265 <html:p>PROTEIN_ASSOCIATION: </html:p>
6266 <html:p>SUBSYSTEM: S_</html:p>
6267 <html:p>PROTEIN_CLASS: </html:p>
6268 </notes>
6269 <listOfReactants>
6270 <speciesReference species="M_din_e" stoichiometry="1.000000"/>
6271 </listOfReactants>
6272 <listOfProducts>
6273 <speciesReference species="M_din_b" stoichiometry="1.000000"/>
6274 </listOfProducts>
6275 </reaction>
6276 <reaction id="R_EX_dms_e_" name="R_Dimethyl_sulfide_exchange" reversible="true">
6277 <notes>
6278 <html:p>GENE_ASSOCIATION: </html:p>
6279 <html:p>PROTEIN_ASSOCIATION: </html:p>
6280 <html:p>SUBSYSTEM: S_</html:p>
6281 <html:p>PROTEIN_CLASS: </html:p>
6282 </notes>
6283 <listOfReactants>
6284 <speciesReference species="M_dms_e" stoichiometry="1.000000"/>
6285 </listOfReactants>
6286 <listOfProducts>
6287 <speciesReference species="M_dms_b" stoichiometry="1.000000"/>
6288 </listOfProducts>
6289 </reaction>
6290 <reaction id="R_EX_dmso_e_" name="R_Dimethyl_sulfoxide_exchange" reversible="true">
6291 <notes>
6292 <html:p>GENE_ASSOCIATION: </html:p>
6293 <html:p>PROTEIN_ASSOCIATION: </html:p>
6294 <html:p>SUBSYSTEM: S_</html:p>
6295 <html:p>PROTEIN_CLASS: </html:p>
6296 </notes>
6297 <listOfReactants>
6298 <speciesReference species="M_dmso_e" stoichiometry="1.000000"/>
6299 </listOfReactants>
6300 <listOfProducts>
6301 <speciesReference species="M_dmso_b" stoichiometry="1.000000"/>
6302 </listOfProducts>
6303 </reaction>
6304 <reaction id="R_EX_duri_e_" name="R_Deoxyuridine_exchange" reversible="true">
6305 <notes>
6306 <html:p>GENE_ASSOCIATION: </html:p>
6307 <html:p>PROTEIN_ASSOCIATION: </html:p>
6308 <html:p>SUBSYSTEM: S_</html:p>
6309 <html:p>PROTEIN_CLASS: </html:p>
6310 </notes>
6311 <listOfReactants>
6312 <speciesReference species="M_duri_e" stoichiometry="1.000000"/>
6313 </listOfReactants>
6314 <listOfProducts>
6315 <speciesReference species="M_duri_b" stoichiometry="1.000000"/>
6316 </listOfProducts>
6317 </reaction>
6318 <reaction id="R_EX_etoh_e_" name="R_Ethanol_exchange" reversible="true">
6319 <notes>
6320 <html:p>GENE_ASSOCIATION: </html:p>
6321 <html:p>PROTEIN_ASSOCIATION: </html:p>
6322 <html:p>SUBSYSTEM: S_</html:p>
6323 <html:p>PROTEIN_CLASS: </html:p>
6324 </notes>
6325 <listOfReactants>
6326 <speciesReference species="M_etoh_e" stoichiometry="1.000000"/>
6327 </listOfReactants>
6328 <listOfProducts>
6329 <speciesReference species="M_etoh_b" stoichiometry="1.000000"/>
6330 </listOfProducts>
6331 </reaction>
6332 <reaction id="R_EX_fe2_e_" name="R_Fe2_exchange" reversible="true">
6333 <notes>
6334 <html:p>GENE_ASSOCIATION: </html:p>
6335 <html:p>PROTEIN_ASSOCIATION: </html:p>
6336 <html:p>SUBSYSTEM: S_</html:p>
6337 <html:p>PROTEIN_CLASS: </html:p>
6338 </notes>
6339 <listOfReactants>
6340 <speciesReference species="M_fe2_e" stoichiometry="1.000000"/>
6341 </listOfReactants>
6342 <listOfProducts>
6343 <speciesReference species="M_fe2_b" stoichiometry="1.000000"/>
6344 </listOfProducts>
6345 </reaction>
6346 <reaction id="R_EX_for_e_" name="R_Formate_exchange" reversible="true">
6347 <notes>
6348 <html:p>GENE_ASSOCIATION: </html:p>
6349 <html:p>PROTEIN_ASSOCIATION: </html:p>
6350 <html:p>SUBSYSTEM: S_</html:p>
6351 <html:p>PROTEIN_CLASS: </html:p>
6352 </notes>
6353 <listOfReactants>
6354 <speciesReference species="M_for_e" stoichiometry="1.000000"/>
6355 </listOfReactants>
6356 <listOfProducts>
6357 <speciesReference species="M_for_b" stoichiometry="1.000000"/>
6358 </listOfProducts>
6359 </reaction>
6360 <reaction id="R_EX_fru_e_" name="R_D_Fructose_exchange" reversible="true">
6361 <notes>
6362 <html:p>GENE_ASSOCIATION: </html:p>
6363 <html:p>PROTEIN_ASSOCIATION: </html:p>
6364 <html:p>SUBSYSTEM: S_</html:p>
6365 <html:p>PROTEIN_CLASS: </html:p>
6366 </notes>
6367 <listOfReactants>
6368 <speciesReference species="M_fru_e" stoichiometry="1.000000"/>
6369 </listOfReactants>
6370 <listOfProducts>
6371 <speciesReference species="M_fru_b" stoichiometry="1.000000"/>
6372 </listOfProducts>
6373 </reaction>
6374 <reaction id="R_EX_fuc1p_L_e_" name="R_L_Fucose_1_phosphate_exchange" reversible="true">
6375 <notes>
6376 <html:p>GENE_ASSOCIATION: </html:p>
6377 <html:p>PROTEIN_ASSOCIATION: </html:p>
6378 <html:p>SUBSYSTEM: S_</html:p>
6379 <html:p>PROTEIN_CLASS: </html:p>
6380 </notes>
6381 <listOfReactants>
6382 <speciesReference species="M_fuc1p_L_e" stoichiometry="1.000000"/>
6383 </listOfReactants>
6384 <listOfProducts>
6385 <speciesReference species="M_fuc1p_L_b" stoichiometry="1.000000"/>
6386 </listOfProducts>
6387 </reaction>
6388 <reaction id="R_EX_fuc_L_e_" name="R_L_Fucose_exchange" reversible="true">
6389 <notes>
6390 <html:p>GENE_ASSOCIATION: </html:p>
6391 <html:p>PROTEIN_ASSOCIATION: </html:p>
6392 <html:p>SUBSYSTEM: S_</html:p>
6393 <html:p>PROTEIN_CLASS: </html:p>
6394 </notes>
6395 <listOfReactants>
6396 <speciesReference species="M_fuc_L_e" stoichiometry="1.000000"/>
6397 </listOfReactants>
6398 <listOfProducts>
6399 <speciesReference species="M_fuc_L_b" stoichiometry="1.000000"/>
6400 </listOfProducts>
6401 </reaction>
6402 <reaction id="R_EX_fum_e_" name="R_Fumarate_exchange" reversible="true">
6403 <notes>
6404 <html:p>GENE_ASSOCIATION: </html:p>
6405 <html:p>PROTEIN_ASSOCIATION: </html:p>
6406 <html:p>SUBSYSTEM: S_</html:p>
6407 <html:p>PROTEIN_CLASS: </html:p>
6408 </notes>
6409 <listOfReactants>
6410 <speciesReference species="M_fum_e" stoichiometry="1.000000"/>
6411 </listOfReactants>
6412 <listOfProducts>
6413 <speciesReference species="M_fum_b" stoichiometry="1.000000"/>
6414 </listOfProducts>
6415 </reaction>
6416 <reaction id="R_EX_g6p_e_" name="R_D_Glucose_6_phosphate_exchange" reversible="true">
6417 <notes>
6418 <html:p>GENE_ASSOCIATION: </html:p>
6419 <html:p>PROTEIN_ASSOCIATION: </html:p>
6420 <html:p>SUBSYSTEM: S_</html:p>
6421 <html:p>PROTEIN_CLASS: </html:p>
6422 </notes>
6423 <listOfReactants>
6424 <speciesReference species="M_g6p_e" stoichiometry="1.000000"/>
6425 </listOfReactants>
6426 <listOfProducts>
6427 <speciesReference species="M_g6p_b" stoichiometry="1.000000"/>
6428 </listOfProducts>
6429 </reaction>
6430 <reaction id="R_EX_gal_e_" name="R_D_Galactose_exchange" reversible="true">
6431 <notes>
6432 <html:p>GENE_ASSOCIATION: </html:p>
6433 <html:p>PROTEIN_ASSOCIATION: </html:p>
6434 <html:p>SUBSYSTEM: S_</html:p>
6435 <html:p>PROTEIN_CLASS: </html:p>
6436 </notes>
6437 <listOfReactants>
6438 <speciesReference species="M_gal_e" stoichiometry="1.000000"/>
6439 </listOfReactants>
6440 <listOfProducts>
6441 <speciesReference species="M_gal_b" stoichiometry="1.000000"/>
6442 </listOfProducts>
6443 </reaction>
6444 <reaction id="R_EX_galct_D_e_" name="R_D_Galactarate_exchange" reversible="true">
6445 <notes>
6446 <html:p>GENE_ASSOCIATION: </html:p>
6447 <html:p>PROTEIN_ASSOCIATION: </html:p>
6448 <html:p>SUBSYSTEM: S_</html:p>
6449 <html:p>PROTEIN_CLASS: </html:p>
6450 </notes>
6451 <listOfReactants>
6452 <speciesReference species="M_galct_D_e" stoichiometry="1.000000"/>
6453 </listOfReactants>
6454 <listOfProducts>
6455 <speciesReference species="M_galct_D_b" stoichiometry="1.000000"/>
6456 </listOfProducts>
6457 </reaction>
6458 <reaction id="R_EX_galctn_D_e_" name="R_D_Galactonate_exchange" reversible="true">
6459 <notes>
6460 <html:p>GENE_ASSOCIATION: </html:p>
6461 <html:p>PROTEIN_ASSOCIATION: </html:p>
6462 <html:p>SUBSYSTEM: S_</html:p>
6463 <html:p>PROTEIN_CLASS: </html:p>
6464 </notes>
6465 <listOfReactants>
6466 <speciesReference species="M_galctn_D_e" stoichiometry="1.000000"/>
6467 </listOfReactants>
6468 <listOfProducts>
6469 <speciesReference species="M_galctn_D_b" stoichiometry="1.000000"/>
6470 </listOfProducts>
6471 </reaction>
6472 <reaction id="R_EX_galt_e_" name="R_Galactitol_exchange" reversible="true">
6473 <notes>
6474 <html:p>GENE_ASSOCIATION: </html:p>
6475 <html:p>PROTEIN_ASSOCIATION: </html:p>
6476 <html:p>SUBSYSTEM: S_</html:p>
6477 <html:p>PROTEIN_CLASS: </html:p>
6478 </notes>
6479 <listOfReactants>
6480 <speciesReference species="M_galt_e" stoichiometry="1.000000"/>
6481 </listOfReactants>
6482 <listOfProducts>
6483 <speciesReference species="M_galt_b" stoichiometry="1.000000"/>
6484 </listOfProducts>
6485 </reaction>
6486 <reaction id="R_EX_galur_e_" name="R_D_Galacturonate_exchange" reversible="true">
6487 <notes>
6488 <html:p>GENE_ASSOCIATION: </html:p>
6489 <html:p>PROTEIN_ASSOCIATION: </html:p>
6490 <html:p>SUBSYSTEM: S_</html:p>
6491 <html:p>PROTEIN_CLASS: </html:p>
6492 </notes>
6493 <listOfReactants>
6494 <speciesReference species="M_galur_e" stoichiometry="1.000000"/>
6495 </listOfReactants>
6496 <listOfProducts>
6497 <speciesReference species="M_galur_b" stoichiometry="1.000000"/>
6498 </listOfProducts>
6499 </reaction>
6500 <reaction id="R_EX_gam_e_" name="R_D_Glucosamine_exchange" reversible="true">
6501 <notes>
6502 <html:p>GENE_ASSOCIATION: </html:p>
6503 <html:p>PROTEIN_ASSOCIATION: </html:p>
6504 <html:p>SUBSYSTEM: S_</html:p>
6505 <html:p>PROTEIN_CLASS: </html:p>
6506 </notes>
6507 <listOfReactants>
6508 <speciesReference species="M_gam_e" stoichiometry="1.000000"/>
6509 </listOfReactants>
6510 <listOfProducts>
6511 <speciesReference species="M_gam_b" stoichiometry="1.000000"/>
6512 </listOfProducts>
6513 </reaction>
6514 <reaction id="R_EX_gbbtn_e_" name="R_gamma_butyrobetaine_exchange" reversible="true">
6515 <notes>
6516 <html:p>GENE_ASSOCIATION: </html:p>
6517 <html:p>PROTEIN_ASSOCIATION: </html:p>
6518 <html:p>SUBSYSTEM: S_</html:p>
6519 <html:p>PROTEIN_CLASS: </html:p>
6520 </notes>
6521 <listOfReactants>
6522 <speciesReference species="M_gbbtn_e" stoichiometry="1.000000"/>
6523 </listOfReactants>
6524 <listOfProducts>
6525 <speciesReference species="M_gbbtn_b" stoichiometry="1.000000"/>
6526 </listOfProducts>
6527 </reaction>
6528 <reaction id="R_EX_glc_e_" name="R_D_Glucose_exchange" reversible="true">
6529 <notes>
6530 <html:p>GENE_ASSOCIATION: </html:p>
6531 <html:p>PROTEIN_ASSOCIATION: </html:p>
6532 <html:p>SUBSYSTEM: S_</html:p>
6533 <html:p>PROTEIN_CLASS: </html:p>
6534 </notes>
6535 <listOfReactants>
6536 <speciesReference species="M_glc_D_e" stoichiometry="1.000000"/>
6537 </listOfReactants>
6538 <listOfProducts>
6539 <speciesReference species="M_glc_D_b" stoichiometry="1.000000"/>
6540 </listOfProducts>
6541 </reaction>
6542 <reaction id="R_EX_glcn_e_" name="R_D_Gluconate_exchange" reversible="true">
6543 <notes>
6544 <html:p>GENE_ASSOCIATION: </html:p>
6545 <html:p>PROTEIN_ASSOCIATION: </html:p>
6546 <html:p>SUBSYSTEM: S_</html:p>
6547 <html:p>PROTEIN_CLASS: </html:p>
6548 </notes>
6549 <listOfReactants>
6550 <speciesReference species="M_glcn_e" stoichiometry="1.000000"/>
6551 </listOfReactants>
6552 <listOfProducts>
6553 <speciesReference species="M_glcn_b" stoichiometry="1.000000"/>
6554 </listOfProducts>
6555 </reaction>
6556 <reaction id="R_EX_glcr_e_" name="R_D_Glucarate_exchange" reversible="true">
6557 <notes>
6558 <html:p>GENE_ASSOCIATION: </html:p>
6559 <html:p>PROTEIN_ASSOCIATION: </html:p>
6560 <html:p>SUBSYSTEM: S_</html:p>
6561 <html:p>PROTEIN_CLASS: </html:p>
6562 </notes>
6563 <listOfReactants>
6564 <speciesReference species="M_glcr_e" stoichiometry="1.000000"/>
6565 </listOfReactants>
6566 <listOfProducts>
6567 <speciesReference species="M_glcr_b" stoichiometry="1.000000"/>
6568 </listOfProducts>
6569 </reaction>
6570 <reaction id="R_EX_glcur_e_" name="R_D_Glucuronate_exchange" reversible="true">
6571 <notes>
6572 <html:p>GENE_ASSOCIATION: </html:p>
6573 <html:p>PROTEIN_ASSOCIATION: </html:p>
6574 <html:p>SUBSYSTEM: S_</html:p>
6575 <html:p>PROTEIN_CLASS: </html:p>
6576 </notes>
6577 <listOfReactants>
6578 <speciesReference species="M_glcur_e" stoichiometry="1.000000"/>
6579 </listOfReactants>
6580 <listOfProducts>
6581 <speciesReference species="M_glcur_b" stoichiometry="1.000000"/>
6582 </listOfProducts>
6583 </reaction>
6584 <reaction id="R_EX_gln_L_e_" name="R_L_Glutamine_exchange" reversible="true">
6585 <notes>
6586 <html:p>GENE_ASSOCIATION: </html:p>
6587 <html:p>PROTEIN_ASSOCIATION: </html:p>
6588 <html:p>SUBSYSTEM: S_</html:p>
6589 <html:p>PROTEIN_CLASS: </html:p>
6590 </notes>
6591 <listOfReactants>
6592 <speciesReference species="M_gln_L_e" stoichiometry="1.000000"/>
6593 </listOfReactants>
6594 <listOfProducts>
6595 <speciesReference species="M_gln_L_b" stoichiometry="1.000000"/>
6596 </listOfProducts>
6597 </reaction>
6598 <reaction id="R_EX_glu_L_e_" name="R_L_Glutamate_exchange" reversible="true">
6599 <notes>
6600 <html:p>GENE_ASSOCIATION: </html:p>
6601 <html:p>PROTEIN_ASSOCIATION: </html:p>
6602 <html:p>SUBSYSTEM: S_</html:p>
6603 <html:p>PROTEIN_CLASS: </html:p>
6604 </notes>
6605 <listOfReactants>
6606 <speciesReference species="M_glu_L_e" stoichiometry="1.000000"/>
6607 </listOfReactants>
6608 <listOfProducts>
6609 <speciesReference species="M_glu_L_b" stoichiometry="1.000000"/>
6610 </listOfProducts>
6611 </reaction>
6612 <reaction id="R_EX_gly_e_" name="R_Glycine_exchange" reversible="true">
6613 <notes>
6614 <html:p>GENE_ASSOCIATION: </html:p>
6615 <html:p>PROTEIN_ASSOCIATION: </html:p>
6616 <html:p>SUBSYSTEM: S_</html:p>
6617 <html:p>PROTEIN_CLASS: </html:p>
6618 </notes>
6619 <listOfReactants>
6620 <speciesReference species="M_gly_e" stoichiometry="1.000000"/>
6621 </listOfReactants>
6622 <listOfProducts>
6623 <speciesReference species="M_gly_b" stoichiometry="1.000000"/>
6624 </listOfProducts>
6625 </reaction>
6626 <reaction id="R_EX_glyald_e_" name="R_D_Glyceraldehyde_exchange" reversible="true">
6627 <notes>
6628 <html:p>GENE_ASSOCIATION: </html:p>
6629 <html:p>PROTEIN_ASSOCIATION: </html:p>
6630 <html:p>SUBSYSTEM: S_</html:p>
6631 <html:p>PROTEIN_CLASS: </html:p>
6632 </notes>
6633 <listOfReactants>
6634 <speciesReference species="M_glyald_e" stoichiometry="1.000000"/>
6635 </listOfReactants>
6636 <listOfProducts>
6637 <speciesReference species="M_glyald_b" stoichiometry="1.000000"/>
6638 </listOfProducts>
6639 </reaction>
6640 <reaction id="R_EX_glyb_e_" name="R_Glycine_betaine_exchange" reversible="true">
6641 <notes>
6642 <html:p>GENE_ASSOCIATION: </html:p>
6643 <html:p>PROTEIN_ASSOCIATION: </html:p>
6644 <html:p>SUBSYSTEM: S_</html:p>
6645 <html:p>PROTEIN_CLASS: </html:p>
6646 </notes>
6647 <listOfReactants>
6648 <speciesReference species="M_glyb_e" stoichiometry="1.000000"/>
6649 </listOfReactants>
6650 <listOfProducts>
6651 <speciesReference species="M_glyb_b" stoichiometry="1.000000"/>
6652 </listOfProducts>
6653 </reaction>
6654 <reaction id="R_EX_glyc3p_e_" name="R_Glycerol_3_phosphate_exchange" reversible="true">
6655 <notes>
6656 <html:p>GENE_ASSOCIATION: </html:p>
6657 <html:p>PROTEIN_ASSOCIATION: </html:p>
6658 <html:p>SUBSYSTEM: S_</html:p>
6659 <html:p>PROTEIN_CLASS: </html:p>
6660 </notes>
6661 <listOfReactants>
6662 <speciesReference species="M_glyc3p_e" stoichiometry="1.000000"/>
6663 </listOfReactants>
6664 <listOfProducts>
6665 <speciesReference species="M_glyc3p_b" stoichiometry="1.000000"/>
6666 </listOfProducts>
6667 </reaction>
6668 <reaction id="R_EX_glyc_e_" name="R_Glycerol_exchange" reversible="true">
6669 <notes>
6670 <html:p>GENE_ASSOCIATION: </html:p>
6671 <html:p>PROTEIN_ASSOCIATION: </html:p>
6672 <html:p>SUBSYSTEM: S_</html:p>
6673 <html:p>PROTEIN_CLASS: </html:p>
6674 </notes>
6675 <listOfReactants>
6676 <speciesReference species="M_glyc_e" stoichiometry="1.000000"/>
6677 </listOfReactants>
6678 <listOfProducts>
6679 <speciesReference species="M_glyc_b" stoichiometry="1.000000"/>
6680 </listOfProducts>
6681 </reaction>
6682 <reaction id="R_EX_glyclt_e_" name="R_Glycolate_exchange" reversible="true">
6683 <notes>
6684 <html:p>GENE_ASSOCIATION: </html:p>
6685 <html:p>PROTEIN_ASSOCIATION: </html:p>
6686 <html:p>SUBSYSTEM: S_</html:p>
6687 <html:p>PROTEIN_CLASS: </html:p>
6688 </notes>
6689 <listOfReactants>
6690 <speciesReference species="M_glyclt_e" stoichiometry="1.000000"/>
6691 </listOfReactants>
6692 <listOfProducts>
6693 <speciesReference species="M_glyclt_b" stoichiometry="1.000000"/>
6694 </listOfProducts>
6695 </reaction>
6696 <reaction id="R_EX_gsn_e_" name="R_Guanosine_exchange" reversible="true">
6697 <notes>
6698 <html:p>GENE_ASSOCIATION: </html:p>
6699 <html:p>PROTEIN_ASSOCIATION: </html:p>
6700 <html:p>SUBSYSTEM: S_</html:p>
6701 <html:p>PROTEIN_CLASS: </html:p>
6702 </notes>
6703 <listOfReactants>
6704 <speciesReference species="M_gsn_e" stoichiometry="1.000000"/>
6705 </listOfReactants>
6706 <listOfProducts>
6707 <speciesReference species="M_gsn_b" stoichiometry="1.000000"/>
6708 </listOfProducts>
6709 </reaction>
6710 <reaction id="R_EX_gua_e_" name="R_Guanine_exchange" reversible="true">
6711 <notes>
6712 <html:p>GENE_ASSOCIATION: </html:p>
6713 <html:p>PROTEIN_ASSOCIATION: </html:p>
6714 <html:p>SUBSYSTEM: S_</html:p>
6715 <html:p>PROTEIN_CLASS: </html:p>
6716 </notes>
6717 <listOfReactants>
6718 <speciesReference species="M_gua_e" stoichiometry="1.000000"/>
6719 </listOfReactants>
6720 <listOfProducts>
6721 <speciesReference species="M_gua_b" stoichiometry="1.000000"/>
6722 </listOfProducts>
6723 </reaction>
6724 <reaction id="R_EX_h2o_e_" name="R_H2O_exchange" reversible="true">
6725 <notes>
6726 <html:p>GENE_ASSOCIATION: </html:p>
6727 <html:p>PROTEIN_ASSOCIATION: </html:p>
6728 <html:p>SUBSYSTEM: S_</html:p>
6729 <html:p>PROTEIN_CLASS: </html:p>
6730 </notes>
6731 <listOfReactants>
6732 <speciesReference species="M_h2o_e" stoichiometry="1.000000"/>
6733 </listOfReactants>
6734 <listOfProducts>
6735 <speciesReference species="M_h2o_b" stoichiometry="1.000000"/>
6736 </listOfProducts>
6737 </reaction>
6738 <reaction id="R_EX_h_e_" name="R_H_exchange" reversible="true">
6739 <notes>
6740 <html:p>GENE_ASSOCIATION: </html:p>
6741 <html:p>PROTEIN_ASSOCIATION: </html:p>
6742 <html:p>SUBSYSTEM: S_</html:p>
6743 <html:p>PROTEIN_CLASS: </html:p>
6744 </notes>
6745 <listOfReactants>
6746 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
6747 </listOfReactants>
6748 <listOfProducts>
6749 <speciesReference species="M_h_b" stoichiometry="1.000000"/>
6750 </listOfProducts>
6751 </reaction>
6752 <reaction id="R_EX_hdca_e_" name="R_Hexadecanoate__n_C160__exchange" reversible="true">
6753 <notes>
6754 <html:p>GENE_ASSOCIATION: </html:p>
6755 <html:p>PROTEIN_ASSOCIATION: </html:p>
6756 <html:p>SUBSYSTEM: S_</html:p>
6757 <html:p>PROTEIN_CLASS: </html:p>
6758 </notes>
6759 <listOfReactants>
6760 <speciesReference species="M_hdca_e" stoichiometry="1.000000"/>
6761 </listOfReactants>
6762 <listOfProducts>
6763 <speciesReference species="M_hdca_b" stoichiometry="1.000000"/>
6764 </listOfProducts>
6765 </reaction>
6766 <reaction id="R_EX_his_L_e_" name="R_L_Histidine_exchange" reversible="true">
6767 <notes>
6768 <html:p>GENE_ASSOCIATION: </html:p>
6769 <html:p>PROTEIN_ASSOCIATION: </html:p>
6770 <html:p>SUBSYSTEM: S_</html:p>
6771 <html:p>PROTEIN_CLASS: </html:p>
6772 </notes>
6773 <listOfReactants>
6774 <speciesReference species="M_his_L_e" stoichiometry="1.000000"/>
6775 </listOfReactants>
6776 <listOfProducts>
6777 <speciesReference species="M_his_L_b" stoichiometry="1.000000"/>
6778 </listOfProducts>
6779 </reaction>
6780 <reaction id="R_EX_hxan_e_" name="R_Hypoxanthine_exchange" reversible="true">
6781 <notes>
6782 <html:p>GENE_ASSOCIATION: </html:p>
6783 <html:p>PROTEIN_ASSOCIATION: </html:p>
6784 <html:p>SUBSYSTEM: S_</html:p>
6785 <html:p>PROTEIN_CLASS: </html:p>
6786 </notes>
6787 <listOfReactants>
6788 <speciesReference species="M_hxan_e" stoichiometry="1.000000"/>
6789 </listOfReactants>
6790 <listOfProducts>
6791 <speciesReference species="M_hxan_b" stoichiometry="1.000000"/>
6792 </listOfProducts>
6793 </reaction>
6794 <reaction id="R_EX_idon_L_e_" name="R_L_Idonate_exchange" reversible="true">
6795 <notes>
6796 <html:p>GENE_ASSOCIATION: </html:p>
6797 <html:p>PROTEIN_ASSOCIATION: </html:p>
6798 <html:p>SUBSYSTEM: S_</html:p>
6799 <html:p>PROTEIN_CLASS: </html:p>
6800 </notes>
6801 <listOfReactants>
6802 <speciesReference species="M_idon_L_e" stoichiometry="1.000000"/>
6803 </listOfReactants>
6804 <listOfProducts>
6805 <speciesReference species="M_idon_L_b" stoichiometry="1.000000"/>
6806 </listOfProducts>
6807 </reaction>
6808 <reaction id="R_EX_ile_L_e_" name="R_L_Isoleucine_exchange" reversible="true">
6809 <notes>
6810 <html:p>GENE_ASSOCIATION: </html:p>
6811 <html:p>PROTEIN_ASSOCIATION: </html:p>
6812 <html:p>SUBSYSTEM: S_</html:p>
6813 <html:p>PROTEIN_CLASS: </html:p>
6814 </notes>
6815 <listOfReactants>
6816 <speciesReference species="M_ile_L_e" stoichiometry="1.000000"/>
6817 </listOfReactants>
6818 <listOfProducts>
6819 <speciesReference species="M_ile_L_b" stoichiometry="1.000000"/>
6820 </listOfProducts>
6821 </reaction>
6822 <reaction id="R_EX_indole_e_" name="R_Indole_exchange" reversible="true">
6823 <notes>
6824 <html:p>GENE_ASSOCIATION: </html:p>
6825 <html:p>PROTEIN_ASSOCIATION: </html:p>
6826 <html:p>SUBSYSTEM: S_</html:p>
6827 <html:p>PROTEIN_CLASS: </html:p>
6828 </notes>
6829 <listOfReactants>
6830 <speciesReference species="M_indole_e" stoichiometry="1.000000"/>
6831 </listOfReactants>
6832 <listOfProducts>
6833 <speciesReference species="M_indole_b" stoichiometry="1.000000"/>
6834 </listOfProducts>
6835 </reaction>
6836 <reaction id="R_EX_ins_e_" name="R_Inosine_exchange" reversible="true">
6837 <notes>
6838 <html:p>GENE_ASSOCIATION: </html:p>
6839 <html:p>PROTEIN_ASSOCIATION: </html:p>
6840 <html:p>SUBSYSTEM: S_</html:p>
6841 <html:p>PROTEIN_CLASS: </html:p>
6842 </notes>
6843 <listOfReactants>
6844 <speciesReference species="M_ins_e" stoichiometry="1.000000"/>
6845 </listOfReactants>
6846 <listOfProducts>
6847 <speciesReference species="M_ins_b" stoichiometry="1.000000"/>
6848 </listOfProducts>
6849 </reaction>
6850 <reaction id="R_EX_k_e_" name="R_K_exchange" reversible="true">
6851 <notes>
6852 <html:p>GENE_ASSOCIATION: </html:p>
6853 <html:p>PROTEIN_ASSOCIATION: </html:p>
6854 <html:p>SUBSYSTEM: S_</html:p>
6855 <html:p>PROTEIN_CLASS: </html:p>
6856 </notes>
6857 <listOfReactants>
6858 <speciesReference species="M_k_e" stoichiometry="1.000000"/>
6859 </listOfReactants>
6860 <listOfProducts>
6861 <speciesReference species="M_k_b" stoichiometry="1.000000"/>
6862 </listOfProducts>
6863 </reaction>
6864 <reaction id="R_EX_lac_D_e_" name="R_D_lactate_exchange" reversible="true">
6865 <notes>
6866 <html:p>GENE_ASSOCIATION: </html:p>
6867 <html:p>PROTEIN_ASSOCIATION: </html:p>
6868 <html:p>SUBSYSTEM: S_</html:p>
6869 <html:p>PROTEIN_CLASS: </html:p>
6870 </notes>
6871 <listOfReactants>
6872 <speciesReference species="M_lac_D_e" stoichiometry="1.000000"/>
6873 </listOfReactants>
6874 <listOfProducts>
6875 <speciesReference species="M_lac_D_b" stoichiometry="1.000000"/>
6876 </listOfProducts>
6877 </reaction>
6878 <reaction id="R_EX_lac_L_e_" name="R_L_Lactate_exchange" reversible="true">
6879 <notes>
6880 <html:p>GENE_ASSOCIATION: </html:p>
6881 <html:p>PROTEIN_ASSOCIATION: </html:p>
6882 <html:p>SUBSYSTEM: S_</html:p>
6883 <html:p>PROTEIN_CLASS: </html:p>
6884 </notes>
6885 <listOfReactants>
6886 <speciesReference species="M_lac_L_e" stoichiometry="1.000000"/>
6887 </listOfReactants>
6888 <listOfProducts>
6889 <speciesReference species="M_lac_L_b" stoichiometry="1.000000"/>
6890 </listOfProducts>
6891 </reaction>
6892 <reaction id="R_EX_lcts_e_" name="R_Lactose_exchange" reversible="true">
6893 <notes>
6894 <html:p>GENE_ASSOCIATION: </html:p>
6895 <html:p>PROTEIN_ASSOCIATION: </html:p>
6896 <html:p>SUBSYSTEM: S_</html:p>
6897 <html:p>PROTEIN_CLASS: </html:p>
6898 </notes>
6899 <listOfReactants>
6900 <speciesReference species="M_lcts_e" stoichiometry="1.000000"/>
6901 </listOfReactants>
6902 <listOfProducts>
6903 <speciesReference species="M_lcts_b" stoichiometry="1.000000"/>
6904 </listOfProducts>
6905 </reaction>
6906 <reaction id="R_EX_leu_L_e_" name="R_L_Leucine_exchange" reversible="true">
6907 <notes>
6908 <html:p>GENE_ASSOCIATION: </html:p>
6909 <html:p>PROTEIN_ASSOCIATION: </html:p>
6910 <html:p>SUBSYSTEM: S_</html:p>
6911 <html:p>PROTEIN_CLASS: </html:p>
6912 </notes>
6913 <listOfReactants>
6914 <speciesReference species="M_leu_L_e" stoichiometry="1.000000"/>
6915 </listOfReactants>
6916 <listOfProducts>
6917 <speciesReference species="M_leu_L_b" stoichiometry="1.000000"/>
6918 </listOfProducts>
6919 </reaction>
6920 <reaction id="R_EX_lys_L_e_" name="R_L_Lysine_exchange" reversible="true">
6921 <notes>
6922 <html:p>GENE_ASSOCIATION: </html:p>
6923 <html:p>PROTEIN_ASSOCIATION: </html:p>
6924 <html:p>SUBSYSTEM: S_</html:p>
6925 <html:p>PROTEIN_CLASS: </html:p>
6926 </notes>
6927 <listOfReactants>
6928 <speciesReference species="M_lys_L_e" stoichiometry="1.000000"/>
6929 </listOfReactants>
6930 <listOfProducts>
6931 <speciesReference species="M_lys_L_b" stoichiometry="1.000000"/>
6932 </listOfProducts>
6933 </reaction>
6934 <reaction id="R_EX_mal_L_e_" name="R_L_Malate_exchange" reversible="true">
6935 <notes>
6936 <html:p>GENE_ASSOCIATION: </html:p>
6937 <html:p>PROTEIN_ASSOCIATION: </html:p>
6938 <html:p>SUBSYSTEM: S_</html:p>
6939 <html:p>PROTEIN_CLASS: </html:p>
6940 </notes>
6941 <listOfReactants>
6942 <speciesReference species="M_mal_L_e" stoichiometry="1.000000"/>
6943 </listOfReactants>
6944 <listOfProducts>
6945 <speciesReference species="M_mal_L_b" stoichiometry="1.000000"/>
6946 </listOfProducts>
6947 </reaction>
6948 <reaction id="R_EX_malt_e_" name="R_Maltose_exchange" reversible="true">
6949 <notes>
6950 <html:p>GENE_ASSOCIATION: </html:p>
6951 <html:p>PROTEIN_ASSOCIATION: </html:p>
6952 <html:p>SUBSYSTEM: S_</html:p>
6953 <html:p>PROTEIN_CLASS: </html:p>
6954 </notes>
6955 <listOfReactants>
6956 <speciesReference species="M_malt_e" stoichiometry="1.000000"/>
6957 </listOfReactants>
6958 <listOfProducts>
6959 <speciesReference species="M_malt_b" stoichiometry="1.000000"/>
6960 </listOfProducts>
6961 </reaction>
6962 <reaction id="R_EX_malthx_e_" name="R_Maltohexaose_exchange" reversible="true">
6963 <notes>
6964 <html:p>GENE_ASSOCIATION: </html:p>
6965 <html:p>PROTEIN_ASSOCIATION: </html:p>
6966 <html:p>SUBSYSTEM: S_</html:p>
6967 <html:p>PROTEIN_CLASS: </html:p>
6968 </notes>
6969 <listOfReactants>
6970 <speciesReference species="M_malthx_e" stoichiometry="1.000000"/>
6971 </listOfReactants>
6972 <listOfProducts>
6973 <speciesReference species="M_malthx_b" stoichiometry="1.000000"/>
6974 </listOfProducts>
6975 </reaction>
6976 <reaction id="R_EX_maltpt_e_" name="R_Maltopentaose_exchange" reversible="true">
6977 <notes>
6978 <html:p>GENE_ASSOCIATION: </html:p>
6979 <html:p>PROTEIN_ASSOCIATION: </html:p>
6980 <html:p>SUBSYSTEM: S_</html:p>
6981 <html:p>PROTEIN_CLASS: </html:p>
6982 </notes>
6983 <listOfReactants>
6984 <speciesReference species="M_maltpt_e" stoichiometry="1.000000"/>
6985 </listOfReactants>
6986 <listOfProducts>
6987 <speciesReference species="M_maltpt_b" stoichiometry="1.000000"/>
6988 </listOfProducts>
6989 </reaction>
6990 <reaction id="R_EX_malttr_e_" name="R_Maltotriose_exchange" reversible="true">
6991 <notes>
6992 <html:p>GENE_ASSOCIATION: </html:p>
6993 <html:p>PROTEIN_ASSOCIATION: </html:p>
6994 <html:p>SUBSYSTEM: S_</html:p>
6995 <html:p>PROTEIN_CLASS: </html:p>
6996 </notes>
6997 <listOfReactants>
6998 <speciesReference species="M_malttr_e" stoichiometry="1.000000"/>
6999 </listOfReactants>
7000 <listOfProducts>
7001 <speciesReference species="M_malttr_b" stoichiometry="1.000000"/>
7002 </listOfProducts>
7003 </reaction>
7004 <reaction id="R_EX_maltttr_e_" name="R_Maltotetraose_exchange" reversible="true">
7005 <notes>
7006 <html:p>GENE_ASSOCIATION: </html:p>
7007 <html:p>PROTEIN_ASSOCIATION: </html:p>
7008 <html:p>SUBSYSTEM: S_</html:p>
7009 <html:p>PROTEIN_CLASS: </html:p>
7010 </notes>
7011 <listOfReactants>
7012 <speciesReference species="M_maltttr_e" stoichiometry="1.000000"/>
7013 </listOfReactants>
7014 <listOfProducts>
7015 <speciesReference species="M_maltttr_b" stoichiometry="1.000000"/>
7016 </listOfProducts>
7017 </reaction>
7018 <reaction id="R_EX_man6p_e_" name="R_D_Mannose_6_phosphate_exchange" reversible="true">
7019 <notes>
7020 <html:p>GENE_ASSOCIATION: </html:p>
7021 <html:p>PROTEIN_ASSOCIATION: </html:p>
7022 <html:p>SUBSYSTEM: S_</html:p>
7023 <html:p>PROTEIN_CLASS: </html:p>
7024 </notes>
7025 <listOfReactants>
7026 <speciesReference species="M_man6p_e" stoichiometry="1.000000"/>
7027 </listOfReactants>
7028 <listOfProducts>
7029 <speciesReference species="M_man6p_b" stoichiometry="1.000000"/>
7030 </listOfProducts>
7031 </reaction>
7032 <reaction id="R_EX_man_e_" name="R_D_Mannose_exchange" reversible="true">
7033 <notes>
7034 <html:p>GENE_ASSOCIATION: </html:p>
7035 <html:p>PROTEIN_ASSOCIATION: </html:p>
7036 <html:p>SUBSYSTEM: S_</html:p>
7037 <html:p>PROTEIN_CLASS: </html:p>
7038 </notes>
7039 <listOfReactants>
7040 <speciesReference species="M_man_e" stoichiometry="1.000000"/>
7041 </listOfReactants>
7042 <listOfProducts>
7043 <speciesReference species="M_man_b" stoichiometry="1.000000"/>
7044 </listOfProducts>
7045 </reaction>
7046 <reaction id="R_EX_melib_e_" name="R_Melibiose_exchange" reversible="true">
7047 <notes>
7048 <html:p>GENE_ASSOCIATION: </html:p>
7049 <html:p>PROTEIN_ASSOCIATION: </html:p>
7050 <html:p>SUBSYSTEM: S_</html:p>
7051 <html:p>PROTEIN_CLASS: </html:p>
7052 </notes>
7053 <listOfReactants>
7054 <speciesReference species="M_melib_e" stoichiometry="1.000000"/>
7055 </listOfReactants>
7056 <listOfProducts>
7057 <speciesReference species="M_melib_b" stoichiometry="1.000000"/>
7058 </listOfProducts>
7059 </reaction>
7060 <reaction id="R_EX_met_D_e_" name="R_D_Methionine_exchange" reversible="true">
7061 <notes>
7062 <html:p>GENE_ASSOCIATION: </html:p>
7063 <html:p>PROTEIN_ASSOCIATION: </html:p>
7064 <html:p>SUBSYSTEM: S_</html:p>
7065 <html:p>PROTEIN_CLASS: </html:p>
7066 </notes>
7067 <listOfReactants>
7068 <speciesReference species="M_met_D_e" stoichiometry="1.000000"/>
7069 </listOfReactants>
7070 <listOfProducts>
7071 <speciesReference species="M_met_D_b" stoichiometry="1.000000"/>
7072 </listOfProducts>
7073 </reaction>
7074 <reaction id="R_EX_met_L_e_" name="R_L_Methionine_exchange" reversible="true">
7075 <notes>
7076 <html:p>GENE_ASSOCIATION: </html:p>
7077 <html:p>PROTEIN_ASSOCIATION: </html:p>
7078 <html:p>SUBSYSTEM: S_</html:p>
7079 <html:p>PROTEIN_CLASS: </html:p>
7080 </notes>
7081 <listOfReactants>
7082 <speciesReference species="M_met_L_e" stoichiometry="1.000000"/>
7083 </listOfReactants>
7084 <listOfProducts>
7085 <speciesReference species="M_met_L_b" stoichiometry="1.000000"/>
7086 </listOfProducts>
7087 </reaction>
7088 <reaction id="R_EX_mnl_e_" name="R_D_Mannitol_exchange" reversible="true">
7089 <notes>
7090 <html:p>GENE_ASSOCIATION: </html:p>
7091 <html:p>PROTEIN_ASSOCIATION: </html:p>
7092 <html:p>SUBSYSTEM: S_</html:p>
7093 <html:p>PROTEIN_CLASS: </html:p>
7094 </notes>
7095 <listOfReactants>
7096 <speciesReference species="M_mnl_e" stoichiometry="1.000000"/>
7097 </listOfReactants>
7098 <listOfProducts>
7099 <speciesReference species="M_mnl_b" stoichiometry="1.000000"/>
7100 </listOfProducts>
7101 </reaction>
7102 <reaction id="R_EX_na1_e_" name="R_Sodium_exchange" reversible="true">
7103 <notes>
7104 <html:p>GENE_ASSOCIATION: </html:p>
7105 <html:p>PROTEIN_ASSOCIATION: </html:p>
7106 <html:p>SUBSYSTEM: S_</html:p>
7107 <html:p>PROTEIN_CLASS: </html:p>
7108 </notes>
7109 <listOfReactants>
7110 <speciesReference species="M_na1_e" stoichiometry="1.000000"/>
7111 </listOfReactants>
7112 <listOfProducts>
7113 <speciesReference species="M_na1_b" stoichiometry="1.000000"/>
7114 </listOfProducts>
7115 </reaction>
7116 <reaction id="R_EX_nac_e_" name="R_Nicotinate_exchange" reversible="true">
7117 <notes>
7118 <html:p>GENE_ASSOCIATION: </html:p>
7119 <html:p>PROTEIN_ASSOCIATION: </html:p>
7120 <html:p>SUBSYSTEM: S_</html:p>
7121 <html:p>PROTEIN_CLASS: </html:p>
7122 </notes>
7123 <listOfReactants>
7124 <speciesReference species="M_nac_e" stoichiometry="1.000000"/>
7125 </listOfReactants>
7126 <listOfProducts>
7127 <speciesReference species="M_nac_b" stoichiometry="1.000000"/>
7128 </listOfProducts>
7129 </reaction>
7130 <reaction id="R_EX_nad_e_" name="R_Nicotinamide_adenine_dinucleotide_exchange" reversible="true">
7131 <notes>
7132 <html:p>GENE_ASSOCIATION: </html:p>
7133 <html:p>PROTEIN_ASSOCIATION: </html:p>
7134 <html:p>SUBSYSTEM: S_</html:p>
7135 <html:p>PROTEIN_CLASS: </html:p>
7136 </notes>
7137 <listOfReactants>
7138 <speciesReference species="M_nad_e" stoichiometry="1.000000"/>
7139 </listOfReactants>
7140 <listOfProducts>
7141 <speciesReference species="M_nad_b" stoichiometry="1.000000"/>
7142 </listOfProducts>
7143 </reaction>
7144 <reaction id="R_EX_nh4_e_" name="R_Ammonia_exchange" reversible="true">
7145 <notes>
7146 <html:p>GENE_ASSOCIATION: </html:p>
7147 <html:p>PROTEIN_ASSOCIATION: </html:p>
7148 <html:p>SUBSYSTEM: S_</html:p>
7149 <html:p>PROTEIN_CLASS: </html:p>
7150 </notes>
7151 <listOfReactants>
7152 <speciesReference species="M_nh4_e" stoichiometry="1.000000"/>
7153 </listOfReactants>
7154 <listOfProducts>
7155 <speciesReference species="M_nh4_b" stoichiometry="1.000000"/>
7156 </listOfProducts>
7157 </reaction>
7158 <reaction id="R_EX_nmn_e_" name="R_NMN_exchange" reversible="true">
7159 <notes>
7160 <html:p>GENE_ASSOCIATION: </html:p>
7161 <html:p>PROTEIN_ASSOCIATION: </html:p>
7162 <html:p>SUBSYSTEM: S_</html:p>
7163 <html:p>PROTEIN_CLASS: </html:p>
7164 </notes>
7165 <listOfReactants>
7166 <speciesReference species="M_nmn_e" stoichiometry="1.000000"/>
7167 </listOfReactants>
7168 <listOfProducts>
7169 <speciesReference species="M_nmn_b" stoichiometry="1.000000"/>
7170 </listOfProducts>
7171 </reaction>
7172 <reaction id="R_EX_no2_e_" name="R_Nitrite_exchange" reversible="true">
7173 <notes>
7174 <html:p>GENE_ASSOCIATION: </html:p>
7175 <html:p>PROTEIN_ASSOCIATION: </html:p>
7176 <html:p>SUBSYSTEM: S_</html:p>
7177 <html:p>PROTEIN_CLASS: </html:p>
7178 </notes>
7179 <listOfReactants>
7180 <speciesReference species="M_no2_e" stoichiometry="1.000000"/>
7181 </listOfReactants>
7182 <listOfProducts>
7183 <speciesReference species="M_no2_b" stoichiometry="1.000000"/>
7184 </listOfProducts>
7185 </reaction>
7186 <reaction id="R_EX_no3_e_" name="R_Nitrate_exchange" reversible="true">
7187 <notes>
7188 <html:p>GENE_ASSOCIATION: </html:p>
7189 <html:p>PROTEIN_ASSOCIATION: </html:p>
7190 <html:p>SUBSYSTEM: S_</html:p>
7191 <html:p>PROTEIN_CLASS: </html:p>
7192 </notes>
7193 <listOfReactants>
7194 <speciesReference species="M_no3_e" stoichiometry="1.000000"/>
7195 </listOfReactants>
7196 <listOfProducts>
7197 <speciesReference species="M_no3_b" stoichiometry="1.000000"/>
7198 </listOfProducts>
7199 </reaction>
7200 <reaction id="R_EX_o2_e_" name="R_O2_exchange" reversible="true">
7201 <notes>
7202 <html:p>GENE_ASSOCIATION: </html:p>
7203 <html:p>PROTEIN_ASSOCIATION: </html:p>
7204 <html:p>SUBSYSTEM: S_</html:p>
7205 <html:p>PROTEIN_CLASS: </html:p>
7206 </notes>
7207 <listOfReactants>
7208 <speciesReference species="M_o2_e" stoichiometry="1.000000"/>
7209 </listOfReactants>
7210 <listOfProducts>
7211 <speciesReference species="M_o2_b" stoichiometry="1.000000"/>
7212 </listOfProducts>
7213 </reaction>
7214 <reaction id="R_EX_ocdca_e_" name="R_octadecanoate__n_C180__exchange" reversible="true">
7215 <notes>
7216 <html:p>GENE_ASSOCIATION: </html:p>
7217 <html:p>PROTEIN_ASSOCIATION: </html:p>
7218 <html:p>SUBSYSTEM: S_</html:p>
7219 <html:p>PROTEIN_CLASS: </html:p>
7220 </notes>
7221 <listOfReactants>
7222 <speciesReference species="M_ocdca_e" stoichiometry="1.000000"/>
7223 </listOfReactants>
7224 <listOfProducts>
7225 <speciesReference species="M_ocdca_b" stoichiometry="1.000000"/>
7226 </listOfProducts>
7227 </reaction>
7228 <reaction id="R_EX_orn_e_" name="R_Ornithine_exchange" reversible="true">
7229 <notes>
7230 <html:p>GENE_ASSOCIATION: </html:p>
7231 <html:p>PROTEIN_ASSOCIATION: </html:p>
7232 <html:p>SUBSYSTEM: S_</html:p>
7233 <html:p>PROTEIN_CLASS: </html:p>
7234 </notes>
7235 <listOfReactants>
7236 <speciesReference species="M_orn_e" stoichiometry="1.000000"/>
7237 </listOfReactants>
7238 <listOfProducts>
7239 <speciesReference species="M_orn_b" stoichiometry="1.000000"/>
7240 </listOfProducts>
7241 </reaction>
7242 <reaction id="R_EX_phe_L_e_" name="R_L_Phenylalanine_exchange" reversible="true">
7243 <notes>
7244 <html:p>GENE_ASSOCIATION: </html:p>
7245 <html:p>PROTEIN_ASSOCIATION: </html:p>
7246 <html:p>SUBSYSTEM: S_</html:p>
7247 <html:p>PROTEIN_CLASS: </html:p>
7248 </notes>
7249 <listOfReactants>
7250 <speciesReference species="M_phe_L_e" stoichiometry="1.000000"/>
7251 </listOfReactants>
7252 <listOfProducts>
7253 <speciesReference species="M_phe_L_b" stoichiometry="1.000000"/>
7254 </listOfProducts>
7255 </reaction>
7256 <reaction id="R_EX_pi_e_" name="R_Phosphate_exchange" reversible="true">
7257 <notes>
7258 <html:p>GENE_ASSOCIATION: </html:p>
7259 <html:p>PROTEIN_ASSOCIATION: </html:p>
7260 <html:p>SUBSYSTEM: S_</html:p>
7261 <html:p>PROTEIN_CLASS: </html:p>
7262 </notes>
7263 <listOfReactants>
7264 <speciesReference species="M_pi_e" stoichiometry="1.000000"/>
7265 </listOfReactants>
7266 <listOfProducts>
7267 <speciesReference species="M_pi_b" stoichiometry="1.000000"/>
7268 </listOfProducts>
7269 </reaction>
7270 <reaction id="R_EX_pnto_R_e_" name="R__R__Pantothenate_exchange" reversible="true">
7271 <notes>
7272 <html:p>GENE_ASSOCIATION: </html:p>
7273 <html:p>PROTEIN_ASSOCIATION: </html:p>
7274 <html:p>SUBSYSTEM: S_</html:p>
7275 <html:p>PROTEIN_CLASS: </html:p>
7276 </notes>
7277 <listOfReactants>
7278 <speciesReference species="M_pnto_R_e" stoichiometry="1.000000"/>
7279 </listOfReactants>
7280 <listOfProducts>
7281 <speciesReference species="M_pnto_R_b" stoichiometry="1.000000"/>
7282 </listOfProducts>
7283 </reaction>
7284 <reaction id="R_EX_pppn_e_" name="R_Phenylpropanoate_exchange" reversible="true">
7285 <notes>
7286 <html:p>GENE_ASSOCIATION: </html:p>
7287 <html:p>PROTEIN_ASSOCIATION: </html:p>
7288 <html:p>SUBSYSTEM: S_</html:p>
7289 <html:p>PROTEIN_CLASS: </html:p>
7290 </notes>
7291 <listOfReactants>
7292 <speciesReference species="M_pppn_e" stoichiometry="1.000000"/>
7293 </listOfReactants>
7294 <listOfProducts>
7295 <speciesReference species="M_pppn_b" stoichiometry="1.000000"/>
7296 </listOfProducts>
7297 </reaction>
7298 <reaction id="R_EX_pro_L_e_" name="R_L_Proline_exchange" reversible="true">
7299 <notes>
7300 <html:p>GENE_ASSOCIATION: </html:p>
7301 <html:p>PROTEIN_ASSOCIATION: </html:p>
7302 <html:p>SUBSYSTEM: S_</html:p>
7303 <html:p>PROTEIN_CLASS: </html:p>
7304 </notes>
7305 <listOfReactants>
7306 <speciesReference species="M_pro_L_e" stoichiometry="1.000000"/>
7307 </listOfReactants>
7308 <listOfProducts>
7309 <speciesReference species="M_pro_L_b" stoichiometry="1.000000"/>
7310 </listOfProducts>
7311 </reaction>
7312 <reaction id="R_EX_ptrc_e_" name="R_Putrescine_exchange" reversible="true">
7313 <notes>
7314 <html:p>GENE_ASSOCIATION: </html:p>
7315 <html:p>PROTEIN_ASSOCIATION: </html:p>
7316 <html:p>SUBSYSTEM: S_</html:p>
7317 <html:p>PROTEIN_CLASS: </html:p>
7318 </notes>
7319 <listOfReactants>
7320 <speciesReference species="M_ptrc_e" stoichiometry="1.000000"/>
7321 </listOfReactants>
7322 <listOfProducts>
7323 <speciesReference species="M_ptrc_b" stoichiometry="1.000000"/>
7324 </listOfProducts>
7325 </reaction>
7326 <reaction id="R_EX_pyr_e_" name="R_Pyruvate_exchange" reversible="true">
7327 <notes>
7328 <html:p>GENE_ASSOCIATION: </html:p>
7329 <html:p>PROTEIN_ASSOCIATION: </html:p>
7330 <html:p>SUBSYSTEM: S_</html:p>
7331 <html:p>PROTEIN_CLASS: </html:p>
7332 </notes>
7333 <listOfReactants>
7334 <speciesReference species="M_pyr_e" stoichiometry="1.000000"/>
7335 </listOfReactants>
7336 <listOfProducts>
7337 <speciesReference species="M_pyr_b" stoichiometry="1.000000"/>
7338 </listOfProducts>
7339 </reaction>
7340 <reaction id="R_EX_rib_D_e_" name="R_D_Ribose_exchange" reversible="true">
7341 <notes>
7342 <html:p>GENE_ASSOCIATION: </html:p>
7343 <html:p>PROTEIN_ASSOCIATION: </html:p>
7344 <html:p>SUBSYSTEM: S_</html:p>
7345 <html:p>PROTEIN_CLASS: </html:p>
7346 </notes>
7347 <listOfReactants>
7348 <speciesReference species="M_rib_D_e" stoichiometry="1.000000"/>
7349 </listOfReactants>
7350 <listOfProducts>
7351 <speciesReference species="M_rib_D_b" stoichiometry="1.000000"/>
7352 </listOfProducts>
7353 </reaction>
7354 <reaction id="R_EX_rmn_e_" name="R_L_Rhamnose_exchange" reversible="true">
7355 <notes>
7356 <html:p>GENE_ASSOCIATION: </html:p>
7357 <html:p>PROTEIN_ASSOCIATION: </html:p>
7358 <html:p>SUBSYSTEM: S_</html:p>
7359 <html:p>PROTEIN_CLASS: </html:p>
7360 </notes>
7361 <listOfReactants>
7362 <speciesReference species="M_rmn_e" stoichiometry="1.000000"/>
7363 </listOfReactants>
7364 <listOfProducts>
7365 <speciesReference species="M_rmn_b" stoichiometry="1.000000"/>
7366 </listOfProducts>
7367 </reaction>
7368 <reaction id="R_EX_sbt_D_e_" name="R_D_Sorbitol_exchange" reversible="true">
7369 <notes>
7370 <html:p>GENE_ASSOCIATION: </html:p>
7371 <html:p>PROTEIN_ASSOCIATION: </html:p>
7372 <html:p>SUBSYSTEM: S_</html:p>
7373 <html:p>PROTEIN_CLASS: </html:p>
7374 </notes>
7375 <listOfReactants>
7376 <speciesReference species="M_sbt_D_e" stoichiometry="1.000000"/>
7377 </listOfReactants>
7378 <listOfProducts>
7379 <speciesReference species="M_sbt_D_b" stoichiometry="1.000000"/>
7380 </listOfProducts>
7381 </reaction>
7382 <reaction id="R_EX_ser_D_e_" name="R_D_Serine_exchange" reversible="true">
7383 <notes>
7384 <html:p>GENE_ASSOCIATION: </html:p>
7385 <html:p>PROTEIN_ASSOCIATION: </html:p>
7386 <html:p>SUBSYSTEM: S_</html:p>
7387 <html:p>PROTEIN_CLASS: </html:p>
7388 </notes>
7389 <listOfReactants>
7390 <speciesReference species="M_ser_D_e" stoichiometry="1.000000"/>
7391 </listOfReactants>
7392 <listOfProducts>
7393 <speciesReference species="M_ser_D_b" stoichiometry="1.000000"/>
7394 </listOfProducts>
7395 </reaction>
7396 <reaction id="R_EX_ser_L_e_" name="R_L_Serine_exchange" reversible="true">
7397 <notes>
7398 <html:p>GENE_ASSOCIATION: </html:p>
7399 <html:p>PROTEIN_ASSOCIATION: </html:p>
7400 <html:p>SUBSYSTEM: S_</html:p>
7401 <html:p>PROTEIN_CLASS: </html:p>
7402 </notes>
7403 <listOfReactants>
7404 <speciesReference species="M_ser_L_e" stoichiometry="1.000000"/>
7405 </listOfReactants>
7406 <listOfProducts>
7407 <speciesReference species="M_ser_L_b" stoichiometry="1.000000"/>
7408 </listOfProducts>
7409 </reaction>
7410 <reaction id="R_EX_so4_e_" name="R_Sulfate_exchange" reversible="true">
7411 <notes>
7412 <html:p>GENE_ASSOCIATION: </html:p>
7413 <html:p>PROTEIN_ASSOCIATION: </html:p>
7414 <html:p>SUBSYSTEM: S_</html:p>
7415 <html:p>PROTEIN_CLASS: </html:p>
7416 </notes>
7417 <listOfReactants>
7418 <speciesReference species="M_so4_e" stoichiometry="1.000000"/>
7419 </listOfReactants>
7420 <listOfProducts>
7421 <speciesReference species="M_so4_b" stoichiometry="1.000000"/>
7422 </listOfProducts>
7423 </reaction>
7424 <reaction id="R_EX_spmd_e_" name="R_Spermidine_exchange" reversible="true">
7425 <notes>
7426 <html:p>GENE_ASSOCIATION: </html:p>
7427 <html:p>PROTEIN_ASSOCIATION: </html:p>
7428 <html:p>SUBSYSTEM: S_</html:p>
7429 <html:p>PROTEIN_CLASS: </html:p>
7430 </notes>
7431 <listOfReactants>
7432 <speciesReference species="M_spmd_e" stoichiometry="1.000000"/>
7433 </listOfReactants>
7434 <listOfProducts>
7435 <speciesReference species="M_spmd_b" stoichiometry="1.000000"/>
7436 </listOfProducts>
7437 </reaction>
7438 <reaction id="R_EX_succ_e_" name="R_Succinate_exchange" reversible="true">
7439 <notes>
7440 <html:p>GENE_ASSOCIATION: </html:p>
7441 <html:p>PROTEIN_ASSOCIATION: </html:p>
7442 <html:p>SUBSYSTEM: S_</html:p>
7443 <html:p>PROTEIN_CLASS: </html:p>
7444 </notes>
7445 <listOfReactants>
7446 <speciesReference species="M_succ_e" stoichiometry="1.000000"/>
7447 </listOfReactants>
7448 <listOfProducts>
7449 <speciesReference species="M_succ_b" stoichiometry="1.000000"/>
7450 </listOfProducts>
7451 </reaction>
7452 <reaction id="R_EX_sucr_e_" name="R_Sucrose_exchange" reversible="true">
7453 <notes>
7454 <html:p>GENE_ASSOCIATION: </html:p>
7455 <html:p>PROTEIN_ASSOCIATION: </html:p>
7456 <html:p>SUBSYSTEM: S_</html:p>
7457 <html:p>PROTEIN_CLASS: </html:p>
7458 </notes>
7459 <listOfReactants>
7460 <speciesReference species="M_sucr_e" stoichiometry="1.000000"/>
7461 </listOfReactants>
7462 <listOfProducts>
7463 <speciesReference species="M_sucr_b" stoichiometry="1.000000"/>
7464 </listOfProducts>
7465 </reaction>
7466 <reaction id="R_EX_tartr_L_e_" name="R_L_tartrate_exchange" reversible="true">
7467 <notes>
7468 <html:p>GENE_ASSOCIATION: </html:p>
7469 <html:p>PROTEIN_ASSOCIATION: </html:p>
7470 <html:p>SUBSYSTEM: S_</html:p>
7471 <html:p>PROTEIN_CLASS: </html:p>
7472 </notes>
7473 <listOfReactants>
7474 <speciesReference species="M_tartr_L_e" stoichiometry="1.000000"/>
7475 </listOfReactants>
7476 <listOfProducts>
7477 <speciesReference species="M_tartr_L_b" stoichiometry="1.000000"/>
7478 </listOfProducts>
7479 </reaction>
7480 <reaction id="R_EX_taur_e_" name="R_Taurine_exchange" reversible="true">
7481 <notes>
7482 <html:p>GENE_ASSOCIATION: </html:p>
7483 <html:p>PROTEIN_ASSOCIATION: </html:p>
7484 <html:p>SUBSYSTEM: S_</html:p>
7485 <html:p>PROTEIN_CLASS: </html:p>
7486 </notes>
7487 <listOfReactants>
7488 <speciesReference species="M_taur_e" stoichiometry="1.000000"/>
7489 </listOfReactants>
7490 <listOfProducts>
7491 <speciesReference species="M_taur_b" stoichiometry="1.000000"/>
7492 </listOfProducts>
7493 </reaction>
7494 <reaction id="R_EX_thm_e_" name="R_Thiamin_exchange" reversible="true">
7495 <notes>
7496 <html:p>GENE_ASSOCIATION: </html:p>
7497 <html:p>PROTEIN_ASSOCIATION: </html:p>
7498 <html:p>SUBSYSTEM: S_</html:p>
7499 <html:p>PROTEIN_CLASS: </html:p>
7500 </notes>
7501 <listOfReactants>
7502 <speciesReference species="M_thm_e" stoichiometry="1.000000"/>
7503 </listOfReactants>
7504 <listOfProducts>
7505 <speciesReference species="M_thm_b" stoichiometry="1.000000"/>
7506 </listOfProducts>
7507 </reaction>
7508 <reaction id="R_EX_thr_L_e_" name="R_L_Threonine_exchange" reversible="true">
7509 <notes>
7510 <html:p>GENE_ASSOCIATION: </html:p>
7511 <html:p>PROTEIN_ASSOCIATION: </html:p>
7512 <html:p>SUBSYSTEM: S_</html:p>
7513 <html:p>PROTEIN_CLASS: </html:p>
7514 </notes>
7515 <listOfReactants>
7516 <speciesReference species="M_thr_L_e" stoichiometry="1.000000"/>
7517 </listOfReactants>
7518 <listOfProducts>
7519 <speciesReference species="M_thr_L_b" stoichiometry="1.000000"/>
7520 </listOfProducts>
7521 </reaction>
7522 <reaction id="R_EX_thymd_e_" name="R_Thymidine_exchange" reversible="true">
7523 <notes>
7524 <html:p>GENE_ASSOCIATION: </html:p>
7525 <html:p>PROTEIN_ASSOCIATION: </html:p>
7526 <html:p>SUBSYSTEM: S_</html:p>
7527 <html:p>PROTEIN_CLASS: </html:p>
7528 </notes>
7529 <listOfReactants>
7530 <speciesReference species="M_thymd_e" stoichiometry="1.000000"/>
7531 </listOfReactants>
7532 <listOfProducts>
7533 <speciesReference species="M_thymd_b" stoichiometry="1.000000"/>
7534 </listOfProducts>
7535 </reaction>
7536 <reaction id="R_EX_tma_e_" name="R_Trimethylamine_exchange" reversible="true">
7537 <notes>
7538 <html:p>GENE_ASSOCIATION: </html:p>
7539 <html:p>PROTEIN_ASSOCIATION: </html:p>
7540 <html:p>SUBSYSTEM: S_</html:p>
7541 <html:p>PROTEIN_CLASS: </html:p>
7542 </notes>
7543 <listOfReactants>
7544 <speciesReference species="M_tma_e" stoichiometry="1.000000"/>
7545 </listOfReactants>
7546 <listOfProducts>
7547 <speciesReference species="M_tma_b" stoichiometry="1.000000"/>
7548 </listOfProducts>
7549 </reaction>
7550 <reaction id="R_EX_tmao_e_" name="R_Trimethylamine_N_oxide_exchange" reversible="true">
7551 <notes>
7552 <html:p>GENE_ASSOCIATION: </html:p>
7553 <html:p>PROTEIN_ASSOCIATION: </html:p>
7554 <html:p>SUBSYSTEM: S_</html:p>
7555 <html:p>PROTEIN_CLASS: </html:p>
7556 </notes>
7557 <listOfReactants>
7558 <speciesReference species="M_tmao_e" stoichiometry="1.000000"/>
7559 </listOfReactants>
7560 <listOfProducts>
7561 <speciesReference species="M_tmao_b" stoichiometry="1.000000"/>
7562 </listOfProducts>
7563 </reaction>
7564 <reaction id="R_EX_tre_e_" name="R_Trehalose_exchange" reversible="true">
7565 <notes>
7566 <html:p>GENE_ASSOCIATION: </html:p>
7567 <html:p>PROTEIN_ASSOCIATION: </html:p>
7568 <html:p>SUBSYSTEM: S_</html:p>
7569 <html:p>PROTEIN_CLASS: </html:p>
7570 </notes>
7571 <listOfReactants>
7572 <speciesReference species="M_tre_e" stoichiometry="1.000000"/>
7573 </listOfReactants>
7574 <listOfProducts>
7575 <speciesReference species="M_tre_b" stoichiometry="1.000000"/>
7576 </listOfProducts>
7577 </reaction>
7578 <reaction id="R_EX_trp_L_e_" name="R_L_Tryptophan_exchange" reversible="true">
7579 <notes>
7580 <html:p>GENE_ASSOCIATION: </html:p>
7581 <html:p>PROTEIN_ASSOCIATION: </html:p>
7582 <html:p>SUBSYSTEM: S_</html:p>
7583 <html:p>PROTEIN_CLASS: </html:p>
7584 </notes>
7585 <listOfReactants>
7586 <speciesReference species="M_trp_L_e" stoichiometry="1.000000"/>
7587 </listOfReactants>
7588 <listOfProducts>
7589 <speciesReference species="M_trp_L_b" stoichiometry="1.000000"/>
7590 </listOfProducts>
7591 </reaction>
7592 <reaction id="R_EX_tsul_e_" name="R_Thiosulfate_exchange" reversible="true">
7593 <notes>
7594 <html:p>GENE_ASSOCIATION: </html:p>
7595 <html:p>PROTEIN_ASSOCIATION: </html:p>
7596 <html:p>SUBSYSTEM: S_</html:p>
7597 <html:p>PROTEIN_CLASS: </html:p>
7598 </notes>
7599 <listOfReactants>
7600 <speciesReference species="M_tsul_e" stoichiometry="1.000000"/>
7601 </listOfReactants>
7602 <listOfProducts>
7603 <speciesReference species="M_tsul_b" stoichiometry="1.000000"/>
7604 </listOfProducts>
7605 </reaction>
7606 <reaction id="R_EX_ttdca_e_" name="R_tetradecanoate__n_C140__exchange" reversible="true">
7607 <notes>
7608 <html:p>GENE_ASSOCIATION: </html:p>
7609 <html:p>PROTEIN_ASSOCIATION: </html:p>
7610 <html:p>SUBSYSTEM: S_</html:p>
7611 <html:p>PROTEIN_CLASS: </html:p>
7612 </notes>
7613 <listOfReactants>
7614 <speciesReference species="M_ttdca_e" stoichiometry="1.000000"/>
7615 </listOfReactants>
7616 <listOfProducts>
7617 <speciesReference species="M_ttdca_b" stoichiometry="1.000000"/>
7618 </listOfProducts>
7619 </reaction>
7620 <reaction id="R_EX_tyr_L_e_" name="R_L_Tyrosine_exchange" reversible="true">
7621 <notes>
7622 <html:p>GENE_ASSOCIATION: </html:p>
7623 <html:p>PROTEIN_ASSOCIATION: </html:p>
7624 <html:p>SUBSYSTEM: S_</html:p>
7625 <html:p>PROTEIN_CLASS: </html:p>
7626 </notes>
7627 <listOfReactants>
7628 <speciesReference species="M_tyr_L_e" stoichiometry="1.000000"/>
7629 </listOfReactants>
7630 <listOfProducts>
7631 <speciesReference species="M_tyr_L_b" stoichiometry="1.000000"/>
7632 </listOfProducts>
7633 </reaction>
7634 <reaction id="R_EX_ura_e_" name="R_Uracil_exchange" reversible="true">
7635 <notes>
7636 <html:p>GENE_ASSOCIATION: </html:p>
7637 <html:p>PROTEIN_ASSOCIATION: </html:p>
7638 <html:p>SUBSYSTEM: S_</html:p>
7639 <html:p>PROTEIN_CLASS: </html:p>
7640 </notes>
7641 <listOfReactants>
7642 <speciesReference species="M_ura_e" stoichiometry="1.000000"/>
7643 </listOfReactants>
7644 <listOfProducts>
7645 <speciesReference species="M_ura_b" stoichiometry="1.000000"/>
7646 </listOfProducts>
7647 </reaction>
7648 <reaction id="R_EX_urea_e_" name="R_Urea_exchange" reversible="true">
7649 <notes>
7650 <html:p>GENE_ASSOCIATION: </html:p>
7651 <html:p>PROTEIN_ASSOCIATION: </html:p>
7652 <html:p>SUBSYSTEM: S_</html:p>
7653 <html:p>PROTEIN_CLASS: </html:p>
7654 </notes>
7655 <listOfReactants>
7656 <speciesReference species="M_urea_e" stoichiometry="1.000000"/>
7657 </listOfReactants>
7658 <listOfProducts>
7659 <speciesReference species="M_urea_b" stoichiometry="1.000000"/>
7660 </listOfProducts>
7661 </reaction>
7662 <reaction id="R_EX_uri_e_" name="R_Uridine_exchange" reversible="true">
7663 <notes>
7664 <html:p>GENE_ASSOCIATION: </html:p>
7665 <html:p>PROTEIN_ASSOCIATION: </html:p>
7666 <html:p>SUBSYSTEM: S_</html:p>
7667 <html:p>PROTEIN_CLASS: </html:p>
7668 </notes>
7669 <listOfReactants>
7670 <speciesReference species="M_uri_e" stoichiometry="1.000000"/>
7671 </listOfReactants>
7672 <listOfProducts>
7673 <speciesReference species="M_uri_b" stoichiometry="1.000000"/>
7674 </listOfProducts>
7675 </reaction>
7676 <reaction id="R_EX_val_L_e_" name="R_L_Valine_exchange" reversible="true">
7677 <notes>
7678 <html:p>GENE_ASSOCIATION: </html:p>
7679 <html:p>PROTEIN_ASSOCIATION: </html:p>
7680 <html:p>SUBSYSTEM: S_</html:p>
7681 <html:p>PROTEIN_CLASS: </html:p>
7682 </notes>
7683 <listOfReactants>
7684 <speciesReference species="M_val_L_e" stoichiometry="1.000000"/>
7685 </listOfReactants>
7686 <listOfProducts>
7687 <speciesReference species="M_val_L_b" stoichiometry="1.000000"/>
7688 </listOfProducts>
7689 </reaction>
7690 <reaction id="R_EX_xan_e_" name="R_Xanthine_exchange" reversible="true">
7691 <notes>
7692 <html:p>GENE_ASSOCIATION: </html:p>
7693 <html:p>PROTEIN_ASSOCIATION: </html:p>
7694 <html:p>SUBSYSTEM: S_</html:p>
7695 <html:p>PROTEIN_CLASS: </html:p>
7696 </notes>
7697 <listOfReactants>
7698 <speciesReference species="M_xan_e" stoichiometry="1.000000"/>
7699 </listOfReactants>
7700 <listOfProducts>
7701 <speciesReference species="M_xan_b" stoichiometry="1.000000"/>
7702 </listOfProducts>
7703 </reaction>
7704 <reaction id="R_EX_xtsn_e_" name="R_Xanthosine_exchange" reversible="true">
7705 <notes>
7706 <html:p>GENE_ASSOCIATION: </html:p>
7707 <html:p>PROTEIN_ASSOCIATION: </html:p>
7708 <html:p>SUBSYSTEM: S_</html:p>
7709 <html:p>PROTEIN_CLASS: </html:p>
7710 </notes>
7711 <listOfReactants>
7712 <speciesReference species="M_xtsn_e" stoichiometry="1.000000"/>
7713 </listOfReactants>
7714 <listOfProducts>
7715 <speciesReference species="M_xtsn_b" stoichiometry="1.000000"/>
7716 </listOfProducts>
7717 </reaction>
7718 <reaction id="R_EX_xyl_D_e_" name="R_D_Xylose_exchange" reversible="true">
7719 <notes>
7720 <html:p>GENE_ASSOCIATION: </html:p>
7721 <html:p>PROTEIN_ASSOCIATION: </html:p>
7722 <html:p>SUBSYSTEM: S_</html:p>
7723 <html:p>PROTEIN_CLASS: </html:p>
7724 </notes>
7725 <listOfReactants>
7726 <speciesReference species="M_xyl_D_e" stoichiometry="1.000000"/>
7727 </listOfReactants>
7728 <listOfProducts>
7729 <speciesReference species="M_xyl_D_b" stoichiometry="1.000000"/>
7730 </listOfProducts>
7731 </reaction>
7732 <reaction id="R_F6PA" name="R_fructose_6_phosphate_aldolase" reversible="true">
7733 <notes>
7734 <html:p>GENE_ASSOCIATION: ( b0825 or b3946 )</html:p>
7735 <html:p>PROTEIN_ASSOCIATION: ( Fsa ) or ( TalC )</html:p>
7736 <html:p>SUBSYSTEM: S_GlycolysisGluconeogenesis</html:p>
7737 <html:p>PROTEIN_CLASS: </html:p>
7738 </notes>
7739 <listOfReactants>
7740 <speciesReference species="M_f6p_c" stoichiometry="1.000000"/>
7741 </listOfReactants>
7742 <listOfProducts>
7743 <speciesReference species="M_dha_c" stoichiometry="1.000000"/>
7744 <speciesReference species="M_g3p_c" stoichiometry="1.000000"/>
7745 </listOfProducts>
7746 </reaction>
7747 <reaction id="R_FAO1" name="R_Fatty_acid_oxidation__tetradecanoate_" reversible="false">
7748 <notes>
7749 <html:p>GENE_ASSOCIATION: ( b3845 and b3846 and b1805 and b0221 )</html:p>
7750 <html:p>PROTEIN_ASSOCIATION: ( FadA and FadB and FadD and FadE )</html:p>
7751 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
7752 <html:p>PROTEIN_CLASS: </html:p>
7753 </notes>
7754 <listOfReactants>
7755 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
7756 <speciesReference species="M_coa_c" stoichiometry="7.000000"/>
7757 <speciesReference species="M_fad_c" stoichiometry="6.000000"/>
7758 <speciesReference species="M_h2o_c" stoichiometry="6.000000"/>
7759 <speciesReference species="M_nad_c" stoichiometry="6.000000"/>
7760 <speciesReference species="M_ttdca_c" stoichiometry="1.000000"/>
7761 </listOfReactants>
7762 <listOfProducts>
7763 <speciesReference species="M_accoa_c" stoichiometry="7.000000"/>
7764 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
7765 <speciesReference species="M_fadh2_c" stoichiometry="6.000000"/>
7766 <speciesReference species="M_h_c" stoichiometry="6.000000"/>
7767 <speciesReference species="M_nadh_c" stoichiometry="6.000000"/>
7768 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
7769 </listOfProducts>
7770 </reaction>
7771 <reaction id="R_FAO2" name="R_Fatty_acid_oxidation__n_C160_" reversible="false">
7772 <notes>
7773 <html:p>GENE_ASSOCIATION: ( b3845 and b3846 and b1805 and b0221 )</html:p>
7774 <html:p>PROTEIN_ASSOCIATION: ( FadA and FadB and FadD and FadE )</html:p>
7775 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
7776 <html:p>PROTEIN_CLASS: </html:p>
7777 </notes>
7778 <listOfReactants>
7779 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
7780 <speciesReference species="M_coa_c" stoichiometry="8.000000"/>
7781 <speciesReference species="M_fad_c" stoichiometry="7.000000"/>
7782 <speciesReference species="M_h2o_c" stoichiometry="7.000000"/>
7783 <speciesReference species="M_hdca_c" stoichiometry="1.000000"/>
7784 <speciesReference species="M_nad_c" stoichiometry="7.000000"/>
7785 </listOfReactants>
7786 <listOfProducts>
7787 <speciesReference species="M_accoa_c" stoichiometry="8.000000"/>
7788 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
7789 <speciesReference species="M_fadh2_c" stoichiometry="7.000000"/>
7790 <speciesReference species="M_h_c" stoichiometry="7.000000"/>
7791 <speciesReference species="M_nadh_c" stoichiometry="7.000000"/>
7792 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
7793 </listOfProducts>
7794 </reaction>
7795 <reaction id="R_FAO3" name="R_Fatty_acid_oxidation__octadecanoate_" reversible="false">
7796 <notes>
7797 <html:p>GENE_ASSOCIATION: ( b3845 and b3846 and b1805 and b0221 )</html:p>
7798 <html:p>PROTEIN_ASSOCIATION: ( FadA and FadB and FadD and FadE )</html:p>
7799 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
7800 <html:p>PROTEIN_CLASS: </html:p>
7801 </notes>
7802 <listOfReactants>
7803 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
7804 <speciesReference species="M_coa_c" stoichiometry="9.000000"/>
7805 <speciesReference species="M_fad_c" stoichiometry="8.000000"/>
7806 <speciesReference species="M_h2o_c" stoichiometry="8.000000"/>
7807 <speciesReference species="M_nad_c" stoichiometry="8.000000"/>
7808 <speciesReference species="M_ocdca_c" stoichiometry="1.000000"/>
7809 </listOfReactants>
7810 <listOfProducts>
7811 <speciesReference species="M_accoa_c" stoichiometry="9.000000"/>
7812 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
7813 <speciesReference species="M_fadh2_c" stoichiometry="8.000000"/>
7814 <speciesReference species="M_h_c" stoichiometry="8.000000"/>
7815 <speciesReference species="M_nadh_c" stoichiometry="8.000000"/>
7816 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
7817 </listOfProducts>
7818 </reaction>
7819 <reaction id="R_FAO4" name="R_fatty_acid_oxidation__Butanoyl_CoA__" reversible="false">
7820 <notes>
7821 <html:p>GENE_ASSOCIATION: ( b3846 and b0221 )</html:p>
7822 <html:p>PROTEIN_ASSOCIATION: ( FadB and FadE )</html:p>
7823 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
7824 <html:p>PROTEIN_CLASS: </html:p>
7825 </notes>
7826 <listOfReactants>
7827 <speciesReference species="M_btcoa_c" stoichiometry="1.000000"/>
7828 <speciesReference species="M_fad_c" stoichiometry="1.000000"/>
7829 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
7830 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
7831 </listOfReactants>
7832 <listOfProducts>
7833 <speciesReference species="M_aacoa_c" stoichiometry="1.000000"/>
7834 <speciesReference species="M_fadh2_c" stoichiometry="1.000000"/>
7835 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
7836 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
7837 </listOfProducts>
7838 </reaction>
7839 <reaction id="R_FBA" name="R_fructose_bisphosphate_aldolase" reversible="true">
7840 <notes>
7841 <html:p>GENE_ASSOCIATION: ( b2925 or b2097 or b1773 )</html:p>
7842 <html:p>PROTEIN_ASSOCIATION: ( FbaA ) or ( FbaB ) or ( B1773 )</html:p>
7843 <html:p>SUBSYSTEM: S_GlycolysisGluconeogenesis</html:p>
7844 <html:p>PROTEIN_CLASS: 4.1.2.13</html:p>
7845 </notes>
7846 <listOfReactants>
7847 <speciesReference species="M_fdp_c" stoichiometry="1.000000"/>
7848 </listOfReactants>
7849 <listOfProducts>
7850 <speciesReference species="M_dhap_c" stoichiometry="1.000000"/>
7851 <speciesReference species="M_g3p_c" stoichiometry="1.000000"/>
7852 </listOfProducts>
7853 </reaction>
7854 <reaction id="R_FBP" name="R_fructose_bisphosphatase" reversible="false">
7855 <notes>
7856 <html:p>GENE_ASSOCIATION: b4232</html:p>
7857 <html:p>PROTEIN_ASSOCIATION: Fbp</html:p>
7858 <html:p>SUBSYSTEM: S_GlycolysisGluconeogenesis</html:p>
7859 <html:p>PROTEIN_CLASS: 3.1.3.11</html:p>
7860 </notes>
7861 <listOfReactants>
7862 <speciesReference species="M_fdp_c" stoichiometry="1.000000"/>
7863 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
7864 </listOfReactants>
7865 <listOfProducts>
7866 <speciesReference species="M_f6p_c" stoichiometry="1.000000"/>
7867 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
7868 </listOfProducts>
7869 </reaction>
7870 <reaction id="R_FCI" name="R_L_fucose_isomerase" reversible="true">
7871 <notes>
7872 <html:p>GENE_ASSOCIATION: b2802</html:p>
7873 <html:p>PROTEIN_ASSOCIATION: FucI</html:p>
7874 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
7875 <html:p>PROTEIN_CLASS: 5.3.1.25</html:p>
7876 </notes>
7877 <listOfReactants>
7878 <speciesReference species="M_fuc_L_c" stoichiometry="1.000000"/>
7879 </listOfReactants>
7880 <listOfProducts>
7881 <speciesReference species="M_fcl_L_c" stoichiometry="1.000000"/>
7882 </listOfProducts>
7883 </reaction>
7884 <reaction id="R_FCLK" name="R_L_fuculokinase" reversible="false">
7885 <notes>
7886 <html:p>GENE_ASSOCIATION: b2803</html:p>
7887 <html:p>PROTEIN_ASSOCIATION: FucK</html:p>
7888 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
7889 <html:p>PROTEIN_CLASS: 2.7.1.51</html:p>
7890 </notes>
7891 <listOfReactants>
7892 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
7893 <speciesReference species="M_fcl_L_c" stoichiometry="1.000000"/>
7894 </listOfReactants>
7895 <listOfProducts>
7896 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
7897 <speciesReference species="M_fc1p_c" stoichiometry="1.000000"/>
7898 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
7899 </listOfProducts>
7900 </reaction>
7901 <reaction id="R_FCLPA" name="R_L_fuculose_1_phosphate_aldolase" reversible="true">
7902 <notes>
7903 <html:p>GENE_ASSOCIATION: ( b2800 or b2738 )</html:p>
7904 <html:p>PROTEIN_ASSOCIATION: ( FucA ) or ( YgbL )</html:p>
7905 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
7906 <html:p>PROTEIN_CLASS: 4.1.2.17</html:p>
7907 </notes>
7908 <listOfReactants>
7909 <speciesReference species="M_fc1p_c" stoichiometry="1.000000"/>
7910 </listOfReactants>
7911 <listOfProducts>
7912 <speciesReference species="M_dhap_c" stoichiometry="1.000000"/>
7913 <speciesReference species="M_lald_L_c" stoichiometry="1.000000"/>
7914 </listOfProducts>
7915 </reaction>
7916 <reaction id="R_FCLT" name="R_Ferrochelatase" reversible="false">
7917 <notes>
7918 <html:p>GENE_ASSOCIATION: b0475</html:p>
7919 <html:p>PROTEIN_ASSOCIATION: HemH</html:p>
7920 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
7921 <html:p>PROTEIN_CLASS: 4.99.1.1</html:p>
7922 </notes>
7923 <listOfReactants>
7924 <speciesReference species="M_fe2_c" stoichiometry="1.000000"/>
7925 <speciesReference species="M_ppp9_c" stoichiometry="1.000000"/>
7926 </listOfReactants>
7927 <listOfProducts>
7928 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
7929 <speciesReference species="M_pheme_c" stoichiometry="1.000000"/>
7930 </listOfProducts>
7931 </reaction>
7932 <reaction id="R_FDH2" name="R_formate_dehydrogenase__quinone_8_2_protons_" reversible="false">
7933 <notes>
7934 <html:p>GENE_ASSOCIATION: ( ( b1474 and b1475 and b1476 ) or ( b3892 and b3893 and b3894 ) or b4079 )</html:p>
7935 <html:p>PROTEIN_ASSOCIATION: ( Fdn ) or ( Fdoec ) or ( FdhF )</html:p>
7936 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
7937 <html:p>PROTEIN_CLASS: 1.2.2.1</html:p>
7938 </notes>
7939 <listOfReactants>
7940 <speciesReference species="M_for_c" stoichiometry="1.000000"/>
7941 <speciesReference species="M_h_c" stoichiometry="3.000000"/>
7942 <speciesReference species="M_q8_c" stoichiometry="1.000000"/>
7943 </listOfReactants>
7944 <listOfProducts>
7945 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
7946 <speciesReference species="M_q8h2_c" stoichiometry="1.000000"/>
7947 <speciesReference species="M_h_e" stoichiometry="2.000000"/>
7948 </listOfProducts>
7949 </reaction>
7950 <reaction id="R_FDH3" name="R_Formate_Dehydrogenase__menaquinone_8_2_protons_" reversible="false">
7951 <notes>
7952 <html:p>GENE_ASSOCIATION: ( ( b3892 and b3893 and b3894 ) or ( b1474 and b1475 and b1476 ) )</html:p>
7953 <html:p>PROTEIN_ASSOCIATION: ( Fdoec ) or ( Fdn )</html:p>
7954 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
7955 <html:p>PROTEIN_CLASS: 1.2.2.1</html:p>
7956 </notes>
7957 <listOfReactants>
7958 <speciesReference species="M_for_c" stoichiometry="1.000000"/>
7959 <speciesReference species="M_h_c" stoichiometry="3.000000"/>
7960 <speciesReference species="M_mqn8_c" stoichiometry="1.000000"/>
7961 </listOfReactants>
7962 <listOfProducts>
7963 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
7964 <speciesReference species="M_mql8_c" stoichiometry="1.000000"/>
7965 <speciesReference species="M_h_e" stoichiometry="2.000000"/>
7966 </listOfProducts>
7967 </reaction>
7968 <reaction id="R_FE2abc" name="R_iron__II__transport_via_ABC_system" reversible="false">
7969 <notes>
7970 <html:p>GENE_ASSOCIATION: b3409</html:p>
7971 <html:p>PROTEIN_ASSOCIATION: FeoB</html:p>
7972 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
7973 <html:p>PROTEIN_CLASS: </html:p>
7974 </notes>
7975 <listOfReactants>
7976 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
7977 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
7978 <speciesReference species="M_fe2_e" stoichiometry="1.000000"/>
7979 </listOfReactants>
7980 <listOfProducts>
7981 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
7982 <speciesReference species="M_fe2_c" stoichiometry="1.000000"/>
7983 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
7984 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
7985 </listOfProducts>
7986 </reaction>
7987 <reaction id="R_FFSD" name="R_beta_fructofuranosidase" reversible="false">
7988 <notes>
7989 <html:p>GENE_ASSOCIATION: </html:p>
7990 <html:p>PROTEIN_ASSOCIATION: </html:p>
7991 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
7992 <html:p>PROTEIN_CLASS: 3.2.1.26</html:p>
7993 </notes>
7994 <listOfReactants>
7995 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
7996 <speciesReference species="M_suc6p_c" stoichiometry="1.000000"/>
7997 </listOfReactants>
7998 <listOfProducts>
7999 <speciesReference species="M_fru_c" stoichiometry="1.000000"/>
8000 <speciesReference species="M_g6p_c" stoichiometry="1.000000"/>
8001 </listOfProducts>
8002 </reaction>
8003 <reaction id="R_FHL" name="R_Formate_hydrogen_lyase" reversible="false">
8004 <notes>
8005 <html:p>GENE_ASSOCIATION: ( b4079 and ( b2719 and b2720 and b2721 and b2722 and b2723 and b2724 ) )</html:p>
8006 <html:p>PROTEIN_ASSOCIATION: ( FdhF and HycB )</html:p>
8007 <html:p>SUBSYSTEM: S_Pyruvate_Metabolism</html:p>
8008 <html:p>PROTEIN_CLASS: </html:p>
8009 </notes>
8010 <listOfReactants>
8011 <speciesReference species="M_for_c" stoichiometry="1.000000"/>
8012 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8013 </listOfReactants>
8014 <listOfProducts>
8015 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
8016 <speciesReference species="M_h2_c" stoichiometry="1.000000"/>
8017 </listOfProducts>
8018 </reaction>
8019 <reaction id="R_FMNAT" name="R_FMN_adenylyltransferase" reversible="false">
8020 <notes>
8021 <html:p>GENE_ASSOCIATION: b0025</html:p>
8022 <html:p>PROTEIN_ASSOCIATION: RibFec</html:p>
8023 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
8024 <html:p>PROTEIN_CLASS: 2.7.7.2</html:p>
8025 </notes>
8026 <listOfReactants>
8027 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
8028 <speciesReference species="M_fmn_c" stoichiometry="1.000000"/>
8029 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8030 </listOfReactants>
8031 <listOfProducts>
8032 <speciesReference species="M_fad_c" stoichiometry="1.000000"/>
8033 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
8034 </listOfProducts>
8035 </reaction>
8036 <reaction id="R_FORt" name="R_formate_transport_via_diffusion" reversible="true">
8037 <notes>
8038 <html:p>GENE_ASSOCIATION: ( b0904 or b2492 )</html:p>
8039 <html:p>PROTEIN_ASSOCIATION: ( FocA ) or ( FocB )</html:p>
8040 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
8041 <html:p>PROTEIN_CLASS: </html:p>
8042 </notes>
8043 <listOfReactants>
8044 <speciesReference species="M_for_e" stoichiometry="1.000000"/>
8045 </listOfReactants>
8046 <listOfProducts>
8047 <speciesReference species="M_for_c" stoichiometry="1.000000"/>
8048 </listOfProducts>
8049 </reaction>
8050 <reaction id="R_FRD2" name="R_fumarate_reductase" reversible="false">
8051 <notes>
8052 <html:p>GENE_ASSOCIATION: ( b4151 and b4152 and b4153 and b4154 )</html:p>
8053 <html:p>PROTEIN_ASSOCIATION: Frd</html:p>
8054 <html:p>SUBSYSTEM: S_Citric_Acid_Cycle</html:p>
8055 <html:p>PROTEIN_CLASS: 1.3.99.1</html:p>
8056 </notes>
8057 <listOfReactants>
8058 <speciesReference species="M_fum_c" stoichiometry="1.000000"/>
8059 <speciesReference species="M_mql8_c" stoichiometry="1.000000"/>
8060 </listOfReactants>
8061 <listOfProducts>
8062 <speciesReference species="M_mqn8_c" stoichiometry="1.000000"/>
8063 <speciesReference species="M_succ_c" stoichiometry="1.000000"/>
8064 </listOfProducts>
8065 </reaction>
8066 <reaction id="R_FRD3" name="R_fumarate_reductase" reversible="false">
8067 <notes>
8068 <html:p>GENE_ASSOCIATION: ( b4151 and b4152 and b4153 and b4154 )</html:p>
8069 <html:p>PROTEIN_ASSOCIATION: Frd</html:p>
8070 <html:p>SUBSYSTEM: S_Citric_Acid_Cycle</html:p>
8071 <html:p>PROTEIN_CLASS: 1.3.99.1</html:p>
8072 </notes>
8073 <listOfReactants>
8074 <speciesReference species="M_2dmmql8_c" stoichiometry="1.000000"/>
8075 <speciesReference species="M_fum_c" stoichiometry="1.000000"/>
8076 </listOfReactants>
8077 <listOfProducts>
8078 <speciesReference species="M_2dmmq8_c" stoichiometry="1.000000"/>
8079 <speciesReference species="M_succ_c" stoichiometry="1.000000"/>
8080 </listOfProducts>
8081 </reaction>
8082 <reaction id="R_FRUK" name="R_fructose_1_phosphate_kinase" reversible="false">
8083 <notes>
8084 <html:p>GENE_ASSOCIATION: b2168</html:p>
8085 <html:p>PROTEIN_ASSOCIATION: FruK</html:p>
8086 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
8087 <html:p>PROTEIN_CLASS: 2.7.1.56</html:p>
8088 </notes>
8089 <listOfReactants>
8090 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
8091 <speciesReference species="M_f1p_c" stoichiometry="1.000000"/>
8092 </listOfReactants>
8093 <listOfProducts>
8094 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
8095 <speciesReference species="M_fdp_c" stoichiometry="1.000000"/>
8096 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8097 </listOfProducts>
8098 </reaction>
8099 <reaction id="R_FRUpts" name="R_D_fructose_transport_via_PEPPyr_PTS" reversible="false">
8100 <notes>
8101 <html:p>GENE_ASSOCIATION: ( b2167 and b2169 and b2415 and b2416 )</html:p>
8102 <html:p>PROTEIN_ASSOCIATION: ( FruAec and FruBec and PtsH and PtsI )</html:p>
8103 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
8104 <html:p>PROTEIN_CLASS: </html:p>
8105 </notes>
8106 <listOfReactants>
8107 <speciesReference species="M_pep_c" stoichiometry="1.000000"/>
8108 <speciesReference species="M_fru_e" stoichiometry="1.000000"/>
8109 </listOfReactants>
8110 <listOfProducts>
8111 <speciesReference species="M_f1p_c" stoichiometry="1.000000"/>
8112 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
8113 </listOfProducts>
8114 </reaction>
8115 <reaction id="R_FRUpts2" name="R_Fructose_transport_via_PEPPyr_PTS__f6p_generating_" reversible="false">
8116 <notes>
8117 <html:p>GENE_ASSOCIATION: ( b1817 and b1818 and b1819 and b2415 and b2416 )</html:p>
8118 <html:p>PROTEIN_ASSOCIATION: ( ManX and ManY and ManZ and PtsH and PtsI )</html:p>
8119 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
8120 <html:p>PROTEIN_CLASS: </html:p>
8121 </notes>
8122 <listOfReactants>
8123 <speciesReference species="M_pep_c" stoichiometry="1.000000"/>
8124 <speciesReference species="M_fru_e" stoichiometry="1.000000"/>
8125 </listOfReactants>
8126 <listOfProducts>
8127 <speciesReference species="M_f6p_c" stoichiometry="1.000000"/>
8128 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
8129 </listOfProducts>
8130 </reaction>
8131 <reaction id="R_FTHFD" name="R_formyltetrahydrofolate_deformylase" reversible="false">
8132 <notes>
8133 <html:p>GENE_ASSOCIATION: b1232</html:p>
8134 <html:p>PROTEIN_ASSOCIATION: PurUec</html:p>
8135 <html:p>SUBSYSTEM: S_Folate_Metabolism</html:p>
8136 <html:p>PROTEIN_CLASS: 3.5.1.10</html:p>
8137 </notes>
8138 <listOfReactants>
8139 <speciesReference species="M_10fthf_c" stoichiometry="1.000000"/>
8140 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
8141 </listOfReactants>
8142 <listOfProducts>
8143 <speciesReference species="M_for_c" stoichiometry="1.000000"/>
8144 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8145 <speciesReference species="M_thf_c" stoichiometry="1.000000"/>
8146 </listOfProducts>
8147 </reaction>
8148 <reaction id="R_FUCPt6_2" name="R_Fucose_1_phosphate_transport_via_phosphate_antiport" reversible="false">
8149 <notes>
8150 <html:p>GENE_ASSOCIATION: b3666</html:p>
8151 <html:p>PROTEIN_ASSOCIATION: UhpT</html:p>
8152 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
8153 <html:p>PROTEIN_CLASS: </html:p>
8154 </notes>
8155 <listOfReactants>
8156 <speciesReference species="M_pi_c" stoichiometry="2.000000"/>
8157 <speciesReference species="M_fuc1p_L_e" stoichiometry="1.000000"/>
8158 </listOfReactants>
8159 <listOfProducts>
8160 <speciesReference species="M_fuc1p_L_c" stoichiometry="1.000000"/>
8161 <speciesReference species="M_pi_e" stoichiometry="2.000000"/>
8162 </listOfProducts>
8163 </reaction>
8164 <reaction id="R_FUCt" name="R_L_fucose_transport_via_proton_symport" reversible="true">
8165 <notes>
8166 <html:p>GENE_ASSOCIATION: b2801</html:p>
8167 <html:p>PROTEIN_ASSOCIATION: FucP</html:p>
8168 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
8169 <html:p>PROTEIN_CLASS: </html:p>
8170 </notes>
8171 <listOfReactants>
8172 <speciesReference species="M_fuc_L_e" stoichiometry="1.000000"/>
8173 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
8174 </listOfReactants>
8175 <listOfProducts>
8176 <speciesReference species="M_fuc_L_c" stoichiometry="1.000000"/>
8177 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8178 </listOfProducts>
8179 </reaction>
8180 <reaction id="R_FUM" name="R_fumarase" reversible="true">
8181 <notes>
8182 <html:p>GENE_ASSOCIATION: ( b1612 or b4122 or b1611 )</html:p>
8183 <html:p>PROTEIN_ASSOCIATION: ( FumA ) or ( FumB ) or ( FumCec )</html:p>
8184 <html:p>SUBSYSTEM: S_Citric_Acid_Cycle</html:p>
8185 <html:p>PROTEIN_CLASS: 4.2.1.2</html:p>
8186 </notes>
8187 <listOfReactants>
8188 <speciesReference species="M_fum_c" stoichiometry="1.000000"/>
8189 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
8190 </listOfReactants>
8191 <listOfProducts>
8192 <speciesReference species="M_mal_L_c" stoichiometry="1.000000"/>
8193 </listOfProducts>
8194 </reaction>
8195 <reaction id="R_FUMt2_2" name="R_Fumarate_transport_via_proton_symport__2_H_" reversible="false">
8196 <notes>
8197 <html:p>GENE_ASSOCIATION: b3528</html:p>
8198 <html:p>PROTEIN_ASSOCIATION: DctA</html:p>
8199 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
8200 <html:p>PROTEIN_CLASS: </html:p>
8201 </notes>
8202 <listOfReactants>
8203 <speciesReference species="M_fum_e" stoichiometry="1.000000"/>
8204 <speciesReference species="M_h_e" stoichiometry="2.000000"/>
8205 </listOfReactants>
8206 <listOfProducts>
8207 <speciesReference species="M_fum_c" stoichiometry="1.000000"/>
8208 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
8209 </listOfProducts>
8210 </reaction>
8211 <reaction id="R_FUMt2_3" name="R_Fumarate_transport_via_proton_symport__3_H_" reversible="false">
8212 <notes>
8213 <html:p>GENE_ASSOCIATION: ( b4138 or b4123 or b0621 )</html:p>
8214 <html:p>PROTEIN_ASSOCIATION: ( DcuA ) or ( DcuB ) or ( DcuC )</html:p>
8215 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
8216 <html:p>PROTEIN_CLASS: </html:p>
8217 </notes>
8218 <listOfReactants>
8219 <speciesReference species="M_fum_e" stoichiometry="1.000000"/>
8220 <speciesReference species="M_h_e" stoichiometry="3.000000"/>
8221 </listOfReactants>
8222 <listOfProducts>
8223 <speciesReference species="M_fum_c" stoichiometry="1.000000"/>
8224 <speciesReference species="M_h_c" stoichiometry="3.000000"/>
8225 </listOfProducts>
8226 </reaction>
8227 <reaction id="R_G1PACT" name="R_glucosamine_1_phosphate_N_acetyltransferase" reversible="false">
8228 <notes>
8229 <html:p>GENE_ASSOCIATION: b3730</html:p>
8230 <html:p>PROTEIN_ASSOCIATION: GlmUec</html:p>
8231 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
8232 <html:p>PROTEIN_CLASS: 2.3.1.157</html:p>
8233 </notes>
8234 <listOfReactants>
8235 <speciesReference species="M_accoa_c" stoichiometry="1.000000"/>
8236 <speciesReference species="M_gam1p_c" stoichiometry="1.000000"/>
8237 </listOfReactants>
8238 <listOfProducts>
8239 <speciesReference species="M_acgam1p_c" stoichiometry="1.000000"/>
8240 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
8241 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8242 </listOfProducts>
8243 </reaction>
8244 <reaction id="R_G1PP" name="R_Glucose_1_phosphatase" reversible="false">
8245 <notes>
8246 <html:p>GENE_ASSOCIATION: b1002</html:p>
8247 <html:p>PROTEIN_ASSOCIATION: Agp</html:p>
8248 <html:p>SUBSYSTEM: S_GlycolysisGluconeogenesis</html:p>
8249 <html:p>PROTEIN_CLASS: 3.1.3.10</html:p>
8250 </notes>
8251 <listOfReactants>
8252 <speciesReference species="M_g1p_c" stoichiometry="1.000000"/>
8253 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
8254 </listOfReactants>
8255 <listOfProducts>
8256 <speciesReference species="M_glc_D_c" stoichiometry="1.000000"/>
8257 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
8258 </listOfProducts>
8259 </reaction>
8260 <reaction id="R_G1PTT" name="R_glucose_1_phosphate_thymidylyltransferase" reversible="false">
8261 <notes>
8262 <html:p>GENE_ASSOCIATION: ( b2039 or b3789 )</html:p>
8263 <html:p>PROTEIN_ASSOCIATION: ( RfbA ) or ( RffH )</html:p>
8264 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
8265 <html:p>PROTEIN_CLASS: 2.7.7.24</html:p>
8266 </notes>
8267 <listOfReactants>
8268 <speciesReference species="M_dttp_c" stoichiometry="1.000000"/>
8269 <speciesReference species="M_g1p_c" stoichiometry="1.000000"/>
8270 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8271 </listOfReactants>
8272 <listOfProducts>
8273 <speciesReference species="M_dtdpglu_c" stoichiometry="1.000000"/>
8274 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
8275 </listOfProducts>
8276 </reaction>
8277 <reaction id="R_G1SATi" name="R_glutamate_1_semialdehyde_aminotransferase" reversible="false">
8278 <notes>
8279 <html:p>GENE_ASSOCIATION: b0154</html:p>
8280 <html:p>PROTEIN_ASSOCIATION: HemLec</html:p>
8281 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
8282 <html:p>PROTEIN_CLASS: 5.4.3.8</html:p>
8283 </notes>
8284 <listOfReactants>
8285 <speciesReference species="M_glu1sa_c" stoichiometry="1.000000"/>
8286 </listOfReactants>
8287 <listOfProducts>
8288 <speciesReference species="M_5aop_c" stoichiometry="1.000000"/>
8289 </listOfProducts>
8290 </reaction>
8291 <reaction id="R_G3PD2" name="R_glycerol_3_phosphate_dehydrogenase__NADP_" reversible="true">
8292 <notes>
8293 <html:p>GENE_ASSOCIATION: b3608</html:p>
8294 <html:p>PROTEIN_ASSOCIATION: GpsA</html:p>
8295 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
8296 <html:p>PROTEIN_CLASS: 1.1.1.94</html:p>
8297 </notes>
8298 <listOfReactants>
8299 <speciesReference species="M_glyc3p_c" stoichiometry="1.000000"/>
8300 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
8301 </listOfReactants>
8302 <listOfProducts>
8303 <speciesReference species="M_dhap_c" stoichiometry="1.000000"/>
8304 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8305 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
8306 </listOfProducts>
8307 </reaction>
8308 <reaction id="R_G3PD5" name="R_glycerol_3_phosphate_dehydrogenase__ubiquinone_8_" reversible="false">
8309 <notes>
8310 <html:p>GENE_ASSOCIATION: ( ( b2241 and b2242 and b2243 ) or b3426 )</html:p>
8311 <html:p>PROTEIN_ASSOCIATION: ( GlpA ) or ( GlpD )</html:p>
8312 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
8313 <html:p>PROTEIN_CLASS: 1.1.99.5</html:p>
8314 </notes>
8315 <listOfReactants>
8316 <speciesReference species="M_glyc3p_c" stoichiometry="1.000000"/>
8317 <speciesReference species="M_q8_c" stoichiometry="1.000000"/>
8318 </listOfReactants>
8319 <listOfProducts>
8320 <speciesReference species="M_dhap_c" stoichiometry="1.000000"/>
8321 <speciesReference species="M_q8h2_c" stoichiometry="1.000000"/>
8322 </listOfProducts>
8323 </reaction>
8324 <reaction id="R_G3PD6" name="R_glycerol_3_phosphate_dehydrogenase__menaquinone_8_" reversible="false">
8325 <notes>
8326 <html:p>GENE_ASSOCIATION: ( b2241 and b2242 and b2243 )</html:p>
8327 <html:p>PROTEIN_ASSOCIATION: GlpA</html:p>
8328 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
8329 <html:p>PROTEIN_CLASS: 1.1.99.5</html:p>
8330 </notes>
8331 <listOfReactants>
8332 <speciesReference species="M_glyc3p_c" stoichiometry="1.000000"/>
8333 <speciesReference species="M_mqn8_c" stoichiometry="1.000000"/>
8334 </listOfReactants>
8335 <listOfProducts>
8336 <speciesReference species="M_dhap_c" stoichiometry="1.000000"/>
8337 <speciesReference species="M_mql8_c" stoichiometry="1.000000"/>
8338 </listOfProducts>
8339 </reaction>
8340 <reaction id="R_G3PD7" name="R_glycerol_3_phosphate_dehydrogenase__demethylmenaquinone_8_" reversible="false">
8341 <notes>
8342 <html:p>GENE_ASSOCIATION: ( b2241 and b2242 and b2243 )</html:p>
8343 <html:p>PROTEIN_ASSOCIATION: GlpA</html:p>
8344 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
8345 <html:p>PROTEIN_CLASS: 1.1.99.5</html:p>
8346 </notes>
8347 <listOfReactants>
8348 <speciesReference species="M_2dmmq8_c" stoichiometry="1.000000"/>
8349 <speciesReference species="M_glyc3p_c" stoichiometry="1.000000"/>
8350 </listOfReactants>
8351 <listOfProducts>
8352 <speciesReference species="M_2dmmql8_c" stoichiometry="1.000000"/>
8353 <speciesReference species="M_dhap_c" stoichiometry="1.000000"/>
8354 </listOfProducts>
8355 </reaction>
8356 <reaction id="R_G5SADs" name="R_L_glutamate_5_semialdehyde_dehydratase__spontaneous_" reversible="false">
8357 <notes>
8358 <html:p>GENE_ASSOCIATION: </html:p>
8359 <html:p>PROTEIN_ASSOCIATION: </html:p>
8360 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
8361 <html:p>PROTEIN_CLASS: </html:p>
8362 </notes>
8363 <listOfReactants>
8364 <speciesReference species="M_glu5sa_c" stoichiometry="1.000000"/>
8365 </listOfReactants>
8366 <listOfProducts>
8367 <speciesReference species="M_1pyr5c_c" stoichiometry="1.000000"/>
8368 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8369 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
8370 </listOfProducts>
8371 </reaction>
8372 <reaction id="R_G5SD" name="R_glutamate_5_semialdehyde_dehydrogenase" reversible="false">
8373 <notes>
8374 <html:p>GENE_ASSOCIATION: b0243</html:p>
8375 <html:p>PROTEIN_ASSOCIATION: ProA</html:p>
8376 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
8377 <html:p>PROTEIN_CLASS: 1.2.1.41</html:p>
8378 </notes>
8379 <listOfReactants>
8380 <speciesReference species="M_glu5p_c" stoichiometry="1.000000"/>
8381 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8382 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
8383 </listOfReactants>
8384 <listOfProducts>
8385 <speciesReference species="M_glu5sa_c" stoichiometry="1.000000"/>
8386 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
8387 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
8388 </listOfProducts>
8389 </reaction>
8390 <reaction id="R_G6PDA" name="R_glucosamine_6_phosphate_deaminase" reversible="false">
8391 <notes>
8392 <html:p>GENE_ASSOCIATION: b0678</html:p>
8393 <html:p>PROTEIN_ASSOCIATION: NagB</html:p>
8394 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
8395 <html:p>PROTEIN_CLASS: 3.5.99.6</html:p>
8396 </notes>
8397 <listOfReactants>
8398 <speciesReference species="M_gam6p_c" stoichiometry="1.000000"/>
8399 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
8400 </listOfReactants>
8401 <listOfProducts>
8402 <speciesReference species="M_f6p_c" stoichiometry="1.000000"/>
8403 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
8404 </listOfProducts>
8405 </reaction>
8406 <reaction id="R_G6PDH2r" name="R_glucose_6_phosphate_dehydrogenase" reversible="true">
8407 <notes>
8408 <html:p>GENE_ASSOCIATION: b1852</html:p>
8409 <html:p>PROTEIN_ASSOCIATION: Zwf</html:p>
8410 <html:p>SUBSYSTEM: S_Pentose_Phosphate_Pathway</html:p>
8411 <html:p>PROTEIN_CLASS: 1.1.1.49</html:p>
8412 </notes>
8413 <listOfReactants>
8414 <speciesReference species="M_g6p_c" stoichiometry="1.000000"/>
8415 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
8416 </listOfReactants>
8417 <listOfProducts>
8418 <speciesReference species="M_6pgl_c" stoichiometry="1.000000"/>
8419 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8420 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
8421 </listOfProducts>
8422 </reaction>
8423 <reaction id="R_G6Pt6_2" name="R_Glucose_6_phosphate_transport_via_phosphate_antiport" reversible="false">
8424 <notes>
8425 <html:p>GENE_ASSOCIATION: b3666</html:p>
8426 <html:p>PROTEIN_ASSOCIATION: UhpT</html:p>
8427 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
8428 <html:p>PROTEIN_CLASS: </html:p>
8429 </notes>
8430 <listOfReactants>
8431 <speciesReference species="M_pi_c" stoichiometry="2.000000"/>
8432 <speciesReference species="M_g6p_e" stoichiometry="1.000000"/>
8433 </listOfReactants>
8434 <listOfProducts>
8435 <speciesReference species="M_g6p_c" stoichiometry="1.000000"/>
8436 <speciesReference species="M_pi_e" stoichiometry="2.000000"/>
8437 </listOfProducts>
8438 </reaction>
8439 <reaction id="R_GALCTD" name="R_galactarate_dehydratase" reversible="false">
8440 <notes>
8441 <html:p>GENE_ASSOCIATION: b3128</html:p>
8442 <html:p>PROTEIN_ASSOCIATION: GarD</html:p>
8443 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
8444 <html:p>PROTEIN_CLASS: 4.2.1.42</html:p>
8445 </notes>
8446 <listOfReactants>
8447 <speciesReference species="M_galct_D_c" stoichiometry="1.000000"/>
8448 </listOfReactants>
8449 <listOfProducts>
8450 <speciesReference species="M_5dh4dglc_c" stoichiometry="1.000000"/>
8451 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
8452 </listOfProducts>
8453 </reaction>
8454 <reaction id="R_GALCTND" name="R_galactonate_dehydratase" reversible="false">
8455 <notes>
8456 <html:p>GENE_ASSOCIATION: b3692</html:p>
8457 <html:p>PROTEIN_ASSOCIATION: DgoA</html:p>
8458 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
8459 <html:p>PROTEIN_CLASS: 4.2.1.6</html:p>
8460 </notes>
8461 <listOfReactants>
8462 <speciesReference species="M_galctn_D_c" stoichiometry="1.000000"/>
8463 </listOfReactants>
8464 <listOfProducts>
8465 <speciesReference species="M_2dh3dgal_c" stoichiometry="1.000000"/>
8466 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
8467 </listOfProducts>
8468 </reaction>
8469 <reaction id="R_GALCTNt2r" name="R_D_galactonate_transport_via_proton_symport__reversible" reversible="true">
8470 <notes>
8471 <html:p>GENE_ASSOCIATION: b3691</html:p>
8472 <html:p>PROTEIN_ASSOCIATION: DgoT</html:p>
8473 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
8474 <html:p>PROTEIN_CLASS: </html:p>
8475 </notes>
8476 <listOfReactants>
8477 <speciesReference species="M_galctn_D_e" stoichiometry="1.000000"/>
8478 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
8479 </listOfReactants>
8480 <listOfProducts>
8481 <speciesReference species="M_galctn_D_c" stoichiometry="1.000000"/>
8482 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8483 </listOfProducts>
8484 </reaction>
8485 <reaction id="R_GALCTt2r" name="R_D_galactarte_transport_via_proton_symport__reversible" reversible="true">
8486 <notes>
8487 <html:p>GENE_ASSOCIATION: b3127</html:p>
8488 <html:p>PROTEIN_ASSOCIATION: GarP</html:p>
8489 <html:p>SUBSYSTEM: S_Putative_Transporters</html:p>
8490 <html:p>PROTEIN_CLASS: </html:p>
8491 </notes>
8492 <listOfReactants>
8493 <speciesReference species="M_galct_D_e" stoichiometry="1.000000"/>
8494 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
8495 </listOfReactants>
8496 <listOfProducts>
8497 <speciesReference species="M_galct_D_c" stoichiometry="1.000000"/>
8498 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8499 </listOfProducts>
8500 </reaction>
8501 <reaction id="R_GALKr" name="R_galactokinase" reversible="true">
8502 <notes>
8503 <html:p>GENE_ASSOCIATION: ( b0757 or b2045 )</html:p>
8504 <html:p>PROTEIN_ASSOCIATION: ( GalK ) or ( WcaK )</html:p>
8505 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
8506 <html:p>PROTEIN_CLASS: 2.7.1.6</html:p>
8507 </notes>
8508 <listOfReactants>
8509 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
8510 <speciesReference species="M_gal_c" stoichiometry="1.000000"/>
8511 </listOfReactants>
8512 <listOfProducts>
8513 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
8514 <speciesReference species="M_gal1p_c" stoichiometry="1.000000"/>
8515 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8516 </listOfProducts>
8517 </reaction>
8518 <reaction id="R_GALS3" name="R_a_galactosidase__melibiose_" reversible="false">
8519 <notes>
8520 <html:p>GENE_ASSOCIATION: b4119</html:p>
8521 <html:p>PROTEIN_ASSOCIATION: MelA</html:p>
8522 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
8523 <html:p>PROTEIN_CLASS: 3.2.1.22</html:p>
8524 </notes>
8525 <listOfReactants>
8526 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
8527 <speciesReference species="M_melib_c" stoichiometry="1.000000"/>
8528 </listOfReactants>
8529 <listOfProducts>
8530 <speciesReference species="M_gal_c" stoichiometry="1.000000"/>
8531 <speciesReference species="M_glc_D_c" stoichiometry="1.000000"/>
8532 </listOfProducts>
8533 </reaction>
8534 <reaction id="R_GALTpts" name="R_Galactitol_transport_via_PEPPyr_PTS" reversible="false">
8535 <notes>
8536 <html:p>GENE_ASSOCIATION: ( b2094 and b2093 and b2092 and b2415 and b2416 )</html:p>
8537 <html:p>PROTEIN_ASSOCIATION: ( GatA and GatB and GatC and PtsH and PtsI )</html:p>
8538 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
8539 <html:p>PROTEIN_CLASS: </html:p>
8540 </notes>
8541 <listOfReactants>
8542 <speciesReference species="M_pep_c" stoichiometry="1.000000"/>
8543 <speciesReference species="M_galt_e" stoichiometry="1.000000"/>
8544 </listOfReactants>
8545 <listOfProducts>
8546 <speciesReference species="M_galt1p_c" stoichiometry="1.000000"/>
8547 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
8548 </listOfProducts>
8549 </reaction>
8550 <reaction id="R_GALU" name="R_UTP_glucose_1_phosphate_uridylyltransferase" reversible="true">
8551 <notes>
8552 <html:p>GENE_ASSOCIATION: b1236</html:p>
8553 <html:p>PROTEIN_ASSOCIATION: GalUec</html:p>
8554 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
8555 <html:p>PROTEIN_CLASS: 2.7.7.9</html:p>
8556 </notes>
8557 <listOfReactants>
8558 <speciesReference species="M_g1p_c" stoichiometry="1.000000"/>
8559 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8560 <speciesReference species="M_utp_c" stoichiometry="1.000000"/>
8561 </listOfReactants>
8562 <listOfProducts>
8563 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
8564 <speciesReference species="M_udpg_c" stoichiometry="1.000000"/>
8565 </listOfProducts>
8566 </reaction>
8567 <reaction id="R_GALURt2r" name="R_D_galacturonate_transport_via_proton_symport__reversible" reversible="true">
8568 <notes>
8569 <html:p>GENE_ASSOCIATION: b3093</html:p>
8570 <html:p>PROTEIN_ASSOCIATION: ExuT</html:p>
8571 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
8572 <html:p>PROTEIN_CLASS: </html:p>
8573 </notes>
8574 <listOfReactants>
8575 <speciesReference species="M_galur_e" stoichiometry="1.000000"/>
8576 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
8577 </listOfReactants>
8578 <listOfProducts>
8579 <speciesReference species="M_galur_c" stoichiometry="1.000000"/>
8580 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8581 </listOfProducts>
8582 </reaction>
8583 <reaction id="R_GALUi" name="R_UTP_glucose_1_phosphate_uridylyltransferase__irreversible_" reversible="false">
8584 <notes>
8585 <html:p>GENE_ASSOCIATION: ( b1236 or b2042 )</html:p>
8586 <html:p>PROTEIN_ASSOCIATION: ( GalUec ) or ( GalF )</html:p>
8587 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
8588 <html:p>PROTEIN_CLASS: 2.7.7.9</html:p>
8589 </notes>
8590 <listOfReactants>
8591 <speciesReference species="M_g1p_c" stoichiometry="1.000000"/>
8592 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8593 <speciesReference species="M_utp_c" stoichiometry="1.000000"/>
8594 </listOfReactants>
8595 <listOfProducts>
8596 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
8597 <speciesReference species="M_udpg_c" stoichiometry="1.000000"/>
8598 </listOfProducts>
8599 </reaction>
8600 <reaction id="R_GALabc" name="R_D_galactose_transport_via_ABC_system" reversible="false">
8601 <notes>
8602 <html:p>GENE_ASSOCIATION: ( b2149 and b2150 and b2148 )</html:p>
8603 <html:p>PROTEIN_ASSOCIATION: ( MglA and MglB and MglC )</html:p>
8604 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
8605 <html:p>PROTEIN_CLASS: </html:p>
8606 </notes>
8607 <listOfReactants>
8608 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
8609 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
8610 <speciesReference species="M_gal_e" stoichiometry="1.000000"/>
8611 </listOfReactants>
8612 <listOfProducts>
8613 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
8614 <speciesReference species="M_gal_c" stoichiometry="1.000000"/>
8615 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8616 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
8617 </listOfProducts>
8618 </reaction>
8619 <reaction id="R_GALt2" name="R_D_galactose_transport_in_via_proton_symport" reversible="false">
8620 <notes>
8621 <html:p>GENE_ASSOCIATION: b2943</html:p>
8622 <html:p>PROTEIN_ASSOCIATION: GalP</html:p>
8623 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
8624 <html:p>PROTEIN_CLASS: </html:p>
8625 </notes>
8626 <listOfReactants>
8627 <speciesReference species="M_gal_e" stoichiometry="1.000000"/>
8628 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
8629 </listOfReactants>
8630 <listOfProducts>
8631 <speciesReference species="M_gal_c" stoichiometry="1.000000"/>
8632 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8633 </listOfProducts>
8634 </reaction>
8635 <reaction id="R_GAMpts" name="R_D_glucosamine_transport_via_PEPPyr_PTS" reversible="false">
8636 <notes>
8637 <html:p>GENE_ASSOCIATION: ( b1817 and b1818 and b1819 and b2415 and b2416 )</html:p>
8638 <html:p>PROTEIN_ASSOCIATION: ( ManX and ManY and ManZ and PtsH and PtsI )</html:p>
8639 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
8640 <html:p>PROTEIN_CLASS: </html:p>
8641 </notes>
8642 <listOfReactants>
8643 <speciesReference species="M_pep_c" stoichiometry="1.000000"/>
8644 <speciesReference species="M_gam_e" stoichiometry="1.000000"/>
8645 </listOfReactants>
8646 <listOfProducts>
8647 <speciesReference species="M_gam6p_c" stoichiometry="1.000000"/>
8648 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
8649 </listOfProducts>
8650 </reaction>
8651 <reaction id="R_GAPD" name="R_glyceraldehyde_3_phosphate_dehydrogenase" reversible="true">
8652 <notes>
8653 <html:p>GENE_ASSOCIATION: ( b1779 or ( b1416 and b1417 ) )</html:p>
8654 <html:p>PROTEIN_ASSOCIATION: ( GapA ) or ( GapC )</html:p>
8655 <html:p>SUBSYSTEM: S_GlycolysisGluconeogenesis</html:p>
8656 <html:p>PROTEIN_CLASS: 1.2.1.12</html:p>
8657 </notes>
8658 <listOfReactants>
8659 <speciesReference species="M_g3p_c" stoichiometry="1.000000"/>
8660 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
8661 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
8662 </listOfReactants>
8663 <listOfProducts>
8664 <speciesReference species="M_13dpg_c" stoichiometry="1.000000"/>
8665 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8666 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
8667 </listOfProducts>
8668 </reaction>
8669 <reaction id="R_GARFT" name="R_phosphoribosylglycinamide_formyltransferase" reversible="true">
8670 <notes>
8671 <html:p>GENE_ASSOCIATION: b2500</html:p>
8672 <html:p>PROTEIN_ASSOCIATION: PurN</html:p>
8673 <html:p>SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis</html:p>
8674 <html:p>PROTEIN_CLASS: 2.1.2.2</html:p>
8675 </notes>
8676 <listOfReactants>
8677 <speciesReference species="M_10fthf_c" stoichiometry="1.000000"/>
8678 <speciesReference species="M_gar_c" stoichiometry="1.000000"/>
8679 </listOfReactants>
8680 <listOfProducts>
8681 <speciesReference species="M_fgam_c" stoichiometry="1.000000"/>
8682 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8683 <speciesReference species="M_thf_c" stoichiometry="1.000000"/>
8684 </listOfProducts>
8685 </reaction>
8686 <reaction id="R_GART" name="R_GAR_transformylase_T" reversible="false">
8687 <notes>
8688 <html:p>GENE_ASSOCIATION: b1849</html:p>
8689 <html:p>PROTEIN_ASSOCIATION: PurT</html:p>
8690 <html:p>SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis</html:p>
8691 <html:p>PROTEIN_CLASS: </html:p>
8692 </notes>
8693 <listOfReactants>
8694 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
8695 <speciesReference species="M_for_c" stoichiometry="1.000000"/>
8696 <speciesReference species="M_gar_c" stoichiometry="1.000000"/>
8697 </listOfReactants>
8698 <listOfProducts>
8699 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
8700 <speciesReference species="M_fgam_c" stoichiometry="1.000000"/>
8701 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8702 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
8703 </listOfProducts>
8704 </reaction>
8705 <reaction id="R_GCALDD" name="R_Glycolaldehyde_dehydrogenase" reversible="false">
8706 <notes>
8707 <html:p>GENE_ASSOCIATION: b1415</html:p>
8708 <html:p>PROTEIN_ASSOCIATION: AldA</html:p>
8709 <html:p>SUBSYSTEM: S_Folate_Metabolism</html:p>
8710 <html:p>PROTEIN_CLASS: 1.2.1.21</html:p>
8711 </notes>
8712 <listOfReactants>
8713 <speciesReference species="M_gcald_c" stoichiometry="1.000000"/>
8714 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
8715 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
8716 </listOfReactants>
8717 <listOfProducts>
8718 <speciesReference species="M_glyclt_c" stoichiometry="1.000000"/>
8719 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
8720 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
8721 </listOfProducts>
8722 </reaction>
8723 <reaction id="R_GDMANE" name="R_GDP_4_dehydro_6_deoxy_D_mannose_epimerase" reversible="false">
8724 <notes>
8725 <html:p>GENE_ASSOCIATION: b2052</html:p>
8726 <html:p>PROTEIN_ASSOCIATION: Fcl</html:p>
8727 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
8728 <html:p>PROTEIN_CLASS: </html:p>
8729 </notes>
8730 <listOfReactants>
8731 <speciesReference species="M_gdpddman_c" stoichiometry="1.000000"/>
8732 </listOfReactants>
8733 <listOfProducts>
8734 <speciesReference species="M_gdpofuc_c" stoichiometry="1.000000"/>
8735 </listOfProducts>
8736 </reaction>
8737 <reaction id="R_GF6PTA" name="R_glutamine_fructose_6_phosphate_transaminase" reversible="false">
8738 <notes>
8739 <html:p>GENE_ASSOCIATION: b3729</html:p>
8740 <html:p>PROTEIN_ASSOCIATION: GlmS</html:p>
8741 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
8742 <html:p>PROTEIN_CLASS: 2.6.1.16</html:p>
8743 </notes>
8744 <listOfReactants>
8745 <speciesReference species="M_f6p_c" stoichiometry="1.000000"/>
8746 <speciesReference species="M_gln_L_c" stoichiometry="1.000000"/>
8747 </listOfReactants>
8748 <listOfProducts>
8749 <speciesReference species="M_gam6p_c" stoichiometry="1.000000"/>
8750 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
8751 </listOfProducts>
8752 </reaction>
8753 <reaction id="R_GHMT2" name="R_glycine_hydroxymethyltransferase" reversible="false">
8754 <notes>
8755 <html:p>GENE_ASSOCIATION: b2551</html:p>
8756 <html:p>PROTEIN_ASSOCIATION: GlyA</html:p>
8757 <html:p>SUBSYSTEM: S_Glycine_and_Serine_Metabolism</html:p>
8758 <html:p>PROTEIN_CLASS: 2.1.2.1</html:p>
8759 </notes>
8760 <listOfReactants>
8761 <speciesReference species="M_ser_L_c" stoichiometry="1.000000"/>
8762 <speciesReference species="M_thf_c" stoichiometry="1.000000"/>
8763 </listOfReactants>
8764 <listOfProducts>
8765 <speciesReference species="M_gly_c" stoichiometry="1.000000"/>
8766 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
8767 <speciesReference species="M_mlthf_c" stoichiometry="1.000000"/>
8768 </listOfProducts>
8769 </reaction>
8770 <reaction id="R_GK1" name="R_guanylate_kinase__GMPATP_" reversible="true">
8771 <notes>
8772 <html:p>GENE_ASSOCIATION: b3648</html:p>
8773 <html:p>PROTEIN_ASSOCIATION: Gmkec</html:p>
8774 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
8775 <html:p>PROTEIN_CLASS: 2.7.4.8</html:p>
8776 </notes>
8777 <listOfReactants>
8778 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
8779 <speciesReference species="M_gmp_c" stoichiometry="1.000000"/>
8780 </listOfReactants>
8781 <listOfProducts>
8782 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
8783 <speciesReference species="M_gdp_c" stoichiometry="1.000000"/>
8784 </listOfProducts>
8785 </reaction>
8786 <reaction id="R_GLCDe" name="R_Glucose_dehydrogenase__ubiquinone_8_as_acceptor_" reversible="false">
8787 <notes>
8788 <html:p>GENE_ASSOCIATION: b0124</html:p>
8789 <html:p>PROTEIN_ASSOCIATION: Gcd</html:p>
8790 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
8791 <html:p>PROTEIN_CLASS: </html:p>
8792 </notes>
8793 <listOfReactants>
8794 <speciesReference species="M_q8_c" stoichiometry="1.000000"/>
8795 <speciesReference species="M_glc_D_e" stoichiometry="1.000000"/>
8796 <speciesReference species="M_h2o_e" stoichiometry="1.000000"/>
8797 </listOfReactants>
8798 <listOfProducts>
8799 <speciesReference species="M_q8h2_c" stoichiometry="1.000000"/>
8800 <speciesReference species="M_glcn_e" stoichiometry="1.000000"/>
8801 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
8802 </listOfProducts>
8803 </reaction>
8804 <reaction id="R_GLCNt2r" name="R_D_gluconate_transport_via_proton_symport__reversible" reversible="true">
8805 <notes>
8806 <html:p>GENE_ASSOCIATION: ( b4265 or b4321 or b3415 )</html:p>
8807 <html:p>PROTEIN_ASSOCIATION: ( IdnT ) or ( GntP ) or ( GntT )</html:p>
8808 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
8809 <html:p>PROTEIN_CLASS: </html:p>
8810 </notes>
8811 <listOfReactants>
8812 <speciesReference species="M_glcn_e" stoichiometry="1.000000"/>
8813 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
8814 </listOfReactants>
8815 <listOfProducts>
8816 <speciesReference species="M_glcn_c" stoichiometry="1.000000"/>
8817 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8818 </listOfProducts>
8819 </reaction>
8820 <reaction id="R_GLCP" name="R_glycogen_phosphorylase" reversible="false">
8821 <notes>
8822 <html:p>GENE_ASSOCIATION: ( b3428 or b3417 )</html:p>
8823 <html:p>PROTEIN_ASSOCIATION: ( GlgP ) or ( MalP )</html:p>
8824 <html:p>SUBSYSTEM: S_GlycolysisGluconeogenesis</html:p>
8825 <html:p>PROTEIN_CLASS: 2.4.1.1</html:p>
8826 </notes>
8827 <listOfReactants>
8828 <speciesReference species="M_glycogen_c" stoichiometry="1.000000"/>
8829 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
8830 </listOfReactants>
8831 <listOfProducts>
8832 <speciesReference species="M_g1p_c" stoichiometry="1.000000"/>
8833 </listOfProducts>
8834 </reaction>
8835 <reaction id="R_GLCRAL" name="R_5_dehydro_4_deoxyglucarate_aldolase" reversible="false">
8836 <notes>
8837 <html:p>GENE_ASSOCIATION: b3126</html:p>
8838 <html:p>PROTEIN_ASSOCIATION: GarL</html:p>
8839 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
8840 <html:p>PROTEIN_CLASS: 4.1.2.20</html:p>
8841 </notes>
8842 <listOfReactants>
8843 <speciesReference species="M_5dh4dglc_c" stoichiometry="1.000000"/>
8844 </listOfReactants>
8845 <listOfProducts>
8846 <speciesReference species="M_2h3oppan_c" stoichiometry="1.000000"/>
8847 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
8848 </listOfProducts>
8849 </reaction>
8850 <reaction id="R_GLCRD" name="R_glucarate_dehydratase" reversible="false">
8851 <notes>
8852 <html:p>GENE_ASSOCIATION: ( b2787 or b2788 )</html:p>
8853 <html:p>PROTEIN_ASSOCIATION: ( GudD ) or ( YgcY )</html:p>
8854 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
8855 <html:p>PROTEIN_CLASS: 4.2.1.40</html:p>
8856 </notes>
8857 <listOfReactants>
8858 <speciesReference species="M_glcr_c" stoichiometry="1.000000"/>
8859 </listOfReactants>
8860 <listOfProducts>
8861 <speciesReference species="M_5dh4dglc_c" stoichiometry="1.000000"/>
8862 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
8863 </listOfProducts>
8864 </reaction>
8865 <reaction id="R_GLCRt2r" name="R_D_glucarate_transport_via_proton_symport__reversible" reversible="true">
8866 <notes>
8867 <html:p>GENE_ASSOCIATION: ( b3127 or b2789 )</html:p>
8868 <html:p>PROTEIN_ASSOCIATION: ( GarP ) or ( GudP )</html:p>
8869 <html:p>SUBSYSTEM: S_Putative_Transporters</html:p>
8870 <html:p>PROTEIN_CLASS: </html:p>
8871 </notes>
8872 <listOfReactants>
8873 <speciesReference species="M_glcr_e" stoichiometry="1.000000"/>
8874 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
8875 </listOfReactants>
8876 <listOfProducts>
8877 <speciesReference species="M_glcr_c" stoichiometry="1.000000"/>
8878 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8879 </listOfProducts>
8880 </reaction>
8881 <reaction id="R_GLCS1" name="R_glycogen_synthase__ADPGlc_" reversible="false">
8882 <notes>
8883 <html:p>GENE_ASSOCIATION: b3429</html:p>
8884 <html:p>PROTEIN_ASSOCIATION: GlgA</html:p>
8885 <html:p>SUBSYSTEM: S_GlycolysisGluconeogenesis</html:p>
8886 <html:p>PROTEIN_CLASS: 2.4.1.21</html:p>
8887 </notes>
8888 <listOfReactants>
8889 <speciesReference species="M_adpglc_c" stoichiometry="1.000000"/>
8890 </listOfReactants>
8891 <listOfProducts>
8892 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
8893 <speciesReference species="M_glycogen_c" stoichiometry="1.000000"/>
8894 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8895 </listOfProducts>
8896 </reaction>
8897 <reaction id="R_GLCURt2r" name="R_D_glucuronate_transport_via_proton_symport__reversible" reversible="true">
8898 <notes>
8899 <html:p>GENE_ASSOCIATION: ( b3093 or b3909 )</html:p>
8900 <html:p>PROTEIN_ASSOCIATION: ( ExuT ) or ( KdgT )</html:p>
8901 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
8902 <html:p>PROTEIN_CLASS: </html:p>
8903 </notes>
8904 <listOfReactants>
8905 <speciesReference species="M_glcur_e" stoichiometry="1.000000"/>
8906 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
8907 </listOfReactants>
8908 <listOfProducts>
8909 <speciesReference species="M_glcur_c" stoichiometry="1.000000"/>
8910 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8911 </listOfProducts>
8912 </reaction>
8913 <reaction id="R_GLCpts" name="R_D_glucose_transport_via_PEPPyr_PTS" reversible="false">
8914 <notes>
8915 <html:p>GENE_ASSOCIATION: ( ( b2417 and b1101 and b2415 and b2416 ) or ( b2417 and b1621 and b2415 and b2416 ) or ( b1817 and b1818 and b1819 and b2415 and b2416 ) )</html:p>
8916 <html:p>PROTEIN_ASSOCIATION: ( Crr and PtsG and PtsH and PtsI ) or ( Crr and MalX and PtsH and PtsI ) or ( ManX and ManY and ManZ and PtsH and PtsI )</html:p>
8917 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
8918 <html:p>PROTEIN_CLASS: </html:p>
8919 </notes>
8920 <listOfReactants>
8921 <speciesReference species="M_pep_c" stoichiometry="1.000000"/>
8922 <speciesReference species="M_glc_D_e" stoichiometry="1.000000"/>
8923 </listOfReactants>
8924 <listOfProducts>
8925 <speciesReference species="M_g6p_c" stoichiometry="1.000000"/>
8926 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
8927 </listOfProducts>
8928 </reaction>
8929 <reaction id="R_GLCt2" name="R_D_glucose_transport_in_via_proton_symport" reversible="false">
8930 <notes>
8931 <html:p>GENE_ASSOCIATION: b2943</html:p>
8932 <html:p>PROTEIN_ASSOCIATION: GalP</html:p>
8933 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
8934 <html:p>PROTEIN_CLASS: </html:p>
8935 </notes>
8936 <listOfReactants>
8937 <speciesReference species="M_glc_D_e" stoichiometry="1.000000"/>
8938 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
8939 </listOfReactants>
8940 <listOfProducts>
8941 <speciesReference species="M_glc_D_c" stoichiometry="1.000000"/>
8942 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8943 </listOfProducts>
8944 </reaction>
8945 <reaction id="R_GLGC" name="R_glucose_1_phosphate_adenylyltransferase" reversible="false">
8946 <notes>
8947 <html:p>GENE_ASSOCIATION: b3430</html:p>
8948 <html:p>PROTEIN_ASSOCIATION: GlgC</html:p>
8949 <html:p>SUBSYSTEM: S_GlycolysisGluconeogenesis</html:p>
8950 <html:p>PROTEIN_CLASS: 2.7.7.27</html:p>
8951 </notes>
8952 <listOfReactants>
8953 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
8954 <speciesReference species="M_g1p_c" stoichiometry="1.000000"/>
8955 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8956 </listOfReactants>
8957 <listOfProducts>
8958 <speciesReference species="M_adpglc_c" stoichiometry="1.000000"/>
8959 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
8960 </listOfProducts>
8961 </reaction>
8962 <reaction id="R_GLNS" name="R_glutamine_synthetase" reversible="false">
8963 <notes>
8964 <html:p>GENE_ASSOCIATION: ( b3870 or b1297 )</html:p>
8965 <html:p>PROTEIN_ASSOCIATION: ( GlnA ) or ( YcjK )</html:p>
8966 <html:p>SUBSYSTEM: S_Glutamate_metabolism</html:p>
8967 <html:p>PROTEIN_CLASS: 6.3.1.2</html:p>
8968 </notes>
8969 <listOfReactants>
8970 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
8971 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
8972 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
8973 </listOfReactants>
8974 <listOfProducts>
8975 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
8976 <speciesReference species="M_gln_L_c" stoichiometry="1.000000"/>
8977 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8978 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
8979 </listOfProducts>
8980 </reaction>
8981 <reaction id="R_GLNabc" name="R_L_glutamine_transport_via_ABC_system" reversible="false">
8982 <notes>
8983 <html:p>GENE_ASSOCIATION: ( b0811 and b0810 and b0809 )</html:p>
8984 <html:p>PROTEIN_ASSOCIATION: ( GlnHec and GlnPec and GlnQec )</html:p>
8985 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
8986 <html:p>PROTEIN_CLASS: </html:p>
8987 </notes>
8988 <listOfReactants>
8989 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
8990 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
8991 <speciesReference species="M_gln_L_e" stoichiometry="1.000000"/>
8992 </listOfReactants>
8993 <listOfProducts>
8994 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
8995 <speciesReference species="M_gln_L_c" stoichiometry="1.000000"/>
8996 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
8997 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
8998 </listOfProducts>
8999 </reaction>
9000 <reaction id="R_GLTPD" name="R_Galactitol_1_phosphate_dehydrogenase" reversible="true">
9001 <notes>
9002 <html:p>GENE_ASSOCIATION: b2091</html:p>
9003 <html:p>PROTEIN_ASSOCIATION: GatD</html:p>
9004 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
9005 <html:p>PROTEIN_CLASS: </html:p>
9006 </notes>
9007 <listOfReactants>
9008 <speciesReference species="M_galt1p_c" stoichiometry="1.000000"/>
9009 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
9010 </listOfReactants>
9011 <listOfProducts>
9012 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9013 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
9014 <speciesReference species="M_tag6p_D_c" stoichiometry="1.000000"/>
9015 </listOfProducts>
9016 </reaction>
9017 <reaction id="R_GLU5K" name="R_glutamate_5_kinase" reversible="false">
9018 <notes>
9019 <html:p>GENE_ASSOCIATION: b0242</html:p>
9020 <html:p>PROTEIN_ASSOCIATION: ProB</html:p>
9021 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
9022 <html:p>PROTEIN_CLASS: 2.7.2.11</html:p>
9023 </notes>
9024 <listOfReactants>
9025 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
9026 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
9027 </listOfReactants>
9028 <listOfProducts>
9029 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
9030 <speciesReference species="M_glu5p_c" stoichiometry="1.000000"/>
9031 </listOfProducts>
9032 </reaction>
9033 <reaction id="R_GLUABUTt7" name="R_4_aminobutyrateglutamate_antiport" reversible="true">
9034 <notes>
9035 <html:p>GENE_ASSOCIATION: b1492</html:p>
9036 <html:p>PROTEIN_ASSOCIATION: XasA</html:p>
9037 <html:p>SUBSYSTEM: S_Putative_Transporters</html:p>
9038 <html:p>PROTEIN_CLASS: </html:p>
9039 </notes>
9040 <listOfReactants>
9041 <speciesReference species="M_4abut_c" stoichiometry="1.000000"/>
9042 <speciesReference species="M_glu_L_e" stoichiometry="1.000000"/>
9043 </listOfReactants>
9044 <listOfProducts>
9045 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
9046 <speciesReference species="M_4abut_e" stoichiometry="1.000000"/>
9047 </listOfProducts>
9048 </reaction>
9049 <reaction id="R_GLUCYS" name="R_gamma_glutamylcysteine_synthetase" reversible="false">
9050 <notes>
9051 <html:p>GENE_ASSOCIATION: b2688</html:p>
9052 <html:p>PROTEIN_ASSOCIATION: GshA</html:p>
9053 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
9054 <html:p>PROTEIN_CLASS: 6.3.2.2</html:p>
9055 </notes>
9056 <listOfReactants>
9057 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
9058 <speciesReference species="M_cys_L_c" stoichiometry="1.000000"/>
9059 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
9060 </listOfReactants>
9061 <listOfProducts>
9062 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
9063 <speciesReference species="M_glucys_c" stoichiometry="1.000000"/>
9064 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9065 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
9066 </listOfProducts>
9067 </reaction>
9068 <reaction id="R_GLUDC" name="R_Glutamate_Decarboxylase" reversible="false">
9069 <notes>
9070 <html:p>GENE_ASSOCIATION: ( b3517 or b1493 )</html:p>
9071 <html:p>PROTEIN_ASSOCIATION: ( GadA ) or ( GadB )</html:p>
9072 <html:p>SUBSYSTEM: S_Glutamate_metabolism</html:p>
9073 <html:p>PROTEIN_CLASS: 4.1.1.15</html:p>
9074 </notes>
9075 <listOfReactants>
9076 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
9077 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9078 </listOfReactants>
9079 <listOfProducts>
9080 <speciesReference species="M_4abut_c" stoichiometry="1.000000"/>
9081 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
9082 </listOfProducts>
9083 </reaction>
9084 <reaction id="R_GLUDy" name="R_glutamate_dehydrogenase__NADP_" reversible="true">
9085 <notes>
9086 <html:p>GENE_ASSOCIATION: b1761</html:p>
9087 <html:p>PROTEIN_ASSOCIATION: GdhA</html:p>
9088 <html:p>SUBSYSTEM: S_Glutamate_metabolism</html:p>
9089 <html:p>PROTEIN_CLASS: 1.4.1.4</html:p>
9090 </notes>
9091 <listOfReactants>
9092 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
9093 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
9094 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
9095 </listOfReactants>
9096 <listOfProducts>
9097 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
9098 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9099 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
9100 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
9101 </listOfProducts>
9102 </reaction>
9103 <reaction id="R_GLUN" name="R_glutaminase" reversible="false">
9104 <notes>
9105 <html:p>GENE_ASSOCIATION: ( b1812 or b0485 or b1524 or b2957 )</html:p>
9106 <html:p>PROTEIN_ASSOCIATION: ( PabBec ) or ( YbaS ) or ( YneH ) or ( AnsB )</html:p>
9107 <html:p>SUBSYSTEM: S_Glutamate_metabolism</html:p>
9108 <html:p>PROTEIN_CLASS: 3.5.1.2</html:p>
9109 </notes>
9110 <listOfReactants>
9111 <speciesReference species="M_gln_L_c" stoichiometry="1.000000"/>
9112 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
9113 </listOfReactants>
9114 <listOfProducts>
9115 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
9116 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
9117 </listOfProducts>
9118 </reaction>
9119 <reaction id="R_GLUPRT" name="R_glutamine_phosphoribosyldiphosphate_amidotransferase" reversible="false">
9120 <notes>
9121 <html:p>GENE_ASSOCIATION: b2312</html:p>
9122 <html:p>PROTEIN_ASSOCIATION: PurF</html:p>
9123 <html:p>SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis</html:p>
9124 <html:p>PROTEIN_CLASS: 2.4.2.14</html:p>
9125 </notes>
9126 <listOfReactants>
9127 <speciesReference species="M_gln_L_c" stoichiometry="1.000000"/>
9128 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
9129 <speciesReference species="M_prpp_c" stoichiometry="1.000000"/>
9130 </listOfReactants>
9131 <listOfProducts>
9132 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
9133 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
9134 <speciesReference species="M_pram_c" stoichiometry="1.000000"/>
9135 </listOfProducts>
9136 </reaction>
9137 <reaction id="R_GLUR" name="R_glutamate_racemase" reversible="true">
9138 <notes>
9139 <html:p>GENE_ASSOCIATION: b3967</html:p>
9140 <html:p>PROTEIN_ASSOCIATION: MurI</html:p>
9141 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
9142 <html:p>PROTEIN_CLASS: 5.1.1.3</html:p>
9143 </notes>
9144 <listOfReactants>
9145 <speciesReference species="M_glu_D_c" stoichiometry="1.000000"/>
9146 </listOfReactants>
9147 <listOfProducts>
9148 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
9149 </listOfProducts>
9150 </reaction>
9151 <reaction id="R_GLUSy" name="R_glutamate_synthase__NADPH_" reversible="false">
9152 <notes>
9153 <html:p>GENE_ASSOCIATION: ( b3212 and b3213 )</html:p>
9154 <html:p>PROTEIN_ASSOCIATION: GltB</html:p>
9155 <html:p>SUBSYSTEM: S_Glutamate_metabolism</html:p>
9156 <html:p>PROTEIN_CLASS: 1.4.1.13</html:p>
9157 </notes>
9158 <listOfReactants>
9159 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
9160 <speciesReference species="M_gln_L_c" stoichiometry="1.000000"/>
9161 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9162 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
9163 </listOfReactants>
9164 <listOfProducts>
9165 <speciesReference species="M_glu_L_c" stoichiometry="2.000000"/>
9166 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
9167 </listOfProducts>
9168 </reaction>
9169 <reaction id="R_GLUTRR" name="R_glutamyl_tRNA_reductase" reversible="false">
9170 <notes>
9171 <html:p>GENE_ASSOCIATION: b1210</html:p>
9172 <html:p>PROTEIN_ASSOCIATION: HemA</html:p>
9173 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
9174 <html:p>PROTEIN_CLASS: </html:p>
9175 </notes>
9176 <listOfReactants>
9177 <speciesReference species="M_glutrna_c" stoichiometry="1.000000"/>
9178 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9179 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
9180 </listOfReactants>
9181 <listOfProducts>
9182 <speciesReference species="M_glu1sa_c" stoichiometry="1.000000"/>
9183 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
9184 <speciesReference species="M_trnaglu_c" stoichiometry="1.000000"/>
9185 </listOfProducts>
9186 </reaction>
9187 <reaction id="R_GLUTRS" name="R_Glutamyl_tRNA_synthetase" reversible="false">
9188 <notes>
9189 <html:p>GENE_ASSOCIATION: b2400</html:p>
9190 <html:p>PROTEIN_ASSOCIATION: GltX</html:p>
9191 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
9192 <html:p>PROTEIN_CLASS: 6.1.1.17</html:p>
9193 </notes>
9194 <listOfReactants>
9195 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
9196 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
9197 <speciesReference species="M_trnaglu_c" stoichiometry="1.000000"/>
9198 </listOfReactants>
9199 <listOfProducts>
9200 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
9201 <speciesReference species="M_glutrna_c" stoichiometry="1.000000"/>
9202 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
9203 </listOfProducts>
9204 </reaction>
9205 <reaction id="R_GLUabc" name="R_L_glutamate_transport_via_ABC_system" reversible="false">
9206 <notes>
9207 <html:p>GENE_ASSOCIATION: ( b0655 and b0654 and b0653 and b0652 )</html:p>
9208 <html:p>PROTEIN_ASSOCIATION: ( GltI and GltJ and GltK and GltL )</html:p>
9209 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
9210 <html:p>PROTEIN_CLASS: </html:p>
9211 </notes>
9212 <listOfReactants>
9213 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
9214 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
9215 <speciesReference species="M_glu_L_e" stoichiometry="1.000000"/>
9216 </listOfReactants>
9217 <listOfProducts>
9218 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
9219 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
9220 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9221 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
9222 </listOfProducts>
9223 </reaction>
9224 <reaction id="R_GLUt2r" name="R_L_glutamate_transport_via_proton_symport__reversible" reversible="true">
9225 <notes>
9226 <html:p>GENE_ASSOCIATION: b4077</html:p>
9227 <html:p>PROTEIN_ASSOCIATION: GltP</html:p>
9228 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
9229 <html:p>PROTEIN_CLASS: </html:p>
9230 </notes>
9231 <listOfReactants>
9232 <speciesReference species="M_glu_L_e" stoichiometry="1.000000"/>
9233 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
9234 </listOfReactants>
9235 <listOfProducts>
9236 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
9237 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9238 </listOfProducts>
9239 </reaction>
9240 <reaction id="R_GLUt4" name="R_Naglutamate_symport" reversible="false">
9241 <notes>
9242 <html:p>GENE_ASSOCIATION: b3653</html:p>
9243 <html:p>PROTEIN_ASSOCIATION: GltS</html:p>
9244 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
9245 <html:p>PROTEIN_CLASS: </html:p>
9246 </notes>
9247 <listOfReactants>
9248 <speciesReference species="M_glu_L_e" stoichiometry="1.000000"/>
9249 <speciesReference species="M_na1_e" stoichiometry="1.000000"/>
9250 </listOfReactants>
9251 <listOfProducts>
9252 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
9253 <speciesReference species="M_na1_c" stoichiometry="1.000000"/>
9254 </listOfProducts>
9255 </reaction>
9256 <reaction id="R_GLXCL" name="R_glyoxalate_carboligase" reversible="false">
9257 <notes>
9258 <html:p>GENE_ASSOCIATION: b0507</html:p>
9259 <html:p>PROTEIN_ASSOCIATION: Gcl</html:p>
9260 <html:p>SUBSYSTEM: S_Glyoxylate_Metabolism</html:p>
9261 <html:p>PROTEIN_CLASS: 4.1.1.47</html:p>
9262 </notes>
9263 <listOfReactants>
9264 <speciesReference species="M_glx_c" stoichiometry="2.000000"/>
9265 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9266 </listOfReactants>
9267 <listOfProducts>
9268 <speciesReference species="M_2h3oppan_c" stoichiometry="1.000000"/>
9269 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
9270 </listOfProducts>
9271 </reaction>
9272 <reaction id="R_GLYALDt" name="R_Glyceraldehyde_facilitated_diffusion" reversible="true">
9273 <notes>
9274 <html:p>GENE_ASSOCIATION: b3927</html:p>
9275 <html:p>PROTEIN_ASSOCIATION: GlpF</html:p>
9276 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
9277 <html:p>PROTEIN_CLASS: </html:p>
9278 </notes>
9279 <listOfReactants>
9280 <speciesReference species="M_glyald_e" stoichiometry="1.000000"/>
9281 </listOfReactants>
9282 <listOfProducts>
9283 <speciesReference species="M_glyald_c" stoichiometry="1.000000"/>
9284 </listOfProducts>
9285 </reaction>
9286 <reaction id="R_GLYATi" name="R_glycine_C_acetyltransferase__irreversible_" reversible="false">
9287 <notes>
9288 <html:p>GENE_ASSOCIATION: b3617</html:p>
9289 <html:p>PROTEIN_ASSOCIATION: Kbl</html:p>
9290 <html:p>SUBSYSTEM: S_Glycine_and_Serine_Metabolism</html:p>
9291 <html:p>PROTEIN_CLASS: 2.3.1.29</html:p>
9292 </notes>
9293 <listOfReactants>
9294 <speciesReference species="M_2aobut_c" stoichiometry="1.000000"/>
9295 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
9296 </listOfReactants>
9297 <listOfProducts>
9298 <speciesReference species="M_accoa_c" stoichiometry="1.000000"/>
9299 <speciesReference species="M_gly_c" stoichiometry="1.000000"/>
9300 </listOfProducts>
9301 </reaction>
9302 <reaction id="R_GLYBabc" name="R_Glycine_betaine_transport_via_ABC_system" reversible="false">
9303 <notes>
9304 <html:p>GENE_ASSOCIATION: ( b2128 and b2129 and b2130 and b2131 )</html:p>
9305 <html:p>PROTEIN_ASSOCIATION: ( YehW and YehX and YehY and YehZ )</html:p>
9306 <html:p>SUBSYSTEM: S_Putative_Transporters</html:p>
9307 <html:p>PROTEIN_CLASS: </html:p>
9308 </notes>
9309 <listOfReactants>
9310 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
9311 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
9312 <speciesReference species="M_glyb_e" stoichiometry="1.000000"/>
9313 </listOfReactants>
9314 <listOfProducts>
9315 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
9316 <speciesReference species="M_glyb_c" stoichiometry="1.000000"/>
9317 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9318 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
9319 </listOfProducts>
9320 </reaction>
9321 <reaction id="R_GLYBt2r" name="R_Glycine_betaine_transport_via_proton_symport__reversible" reversible="true">
9322 <notes>
9323 <html:p>GENE_ASSOCIATION: b1801</html:p>
9324 <html:p>PROTEIN_ASSOCIATION: YeaV</html:p>
9325 <html:p>SUBSYSTEM: S_Putative_Transporters</html:p>
9326 <html:p>PROTEIN_CLASS: </html:p>
9327 </notes>
9328 <listOfReactants>
9329 <speciesReference species="M_glyb_e" stoichiometry="1.000000"/>
9330 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
9331 </listOfReactants>
9332 <listOfProducts>
9333 <speciesReference species="M_glyb_c" stoichiometry="1.000000"/>
9334 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9335 </listOfProducts>
9336 </reaction>
9337 <reaction id="R_GLYC3Pabc" name="R_sn_Glycerol_3_phosphate_transport_via_ABC_system" reversible="false">
9338 <notes>
9339 <html:p>GENE_ASSOCIATION: ( b3452 and b3453 and b3450 and b3451 )</html:p>
9340 <html:p>PROTEIN_ASSOCIATION: ( UgpA and UgpB and UgpC and UgpE )</html:p>
9341 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
9342 <html:p>PROTEIN_CLASS: </html:p>
9343 </notes>
9344 <listOfReactants>
9345 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
9346 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
9347 <speciesReference species="M_glyc3p_e" stoichiometry="1.000000"/>
9348 </listOfReactants>
9349 <listOfProducts>
9350 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
9351 <speciesReference species="M_glyc3p_c" stoichiometry="1.000000"/>
9352 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9353 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
9354 </listOfProducts>
9355 </reaction>
9356 <reaction id="R_GLYC3Pt6" name="R_Glycerol_3_phosphate__phosphate_antiporter" reversible="false">
9357 <notes>
9358 <html:p>GENE_ASSOCIATION: b2240</html:p>
9359 <html:p>PROTEIN_ASSOCIATION: GlpT</html:p>
9360 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
9361 <html:p>PROTEIN_CLASS: </html:p>
9362 </notes>
9363 <listOfReactants>
9364 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
9365 <speciesReference species="M_glyc3p_e" stoichiometry="1.000000"/>
9366 </listOfReactants>
9367 <listOfProducts>
9368 <speciesReference species="M_glyc3p_c" stoichiometry="1.000000"/>
9369 <speciesReference species="M_pi_e" stoichiometry="1.000000"/>
9370 </listOfProducts>
9371 </reaction>
9372 <reaction id="R_GLYCDx" name="R_Glycerol_dehydrogenase" reversible="false">
9373 <notes>
9374 <html:p>GENE_ASSOCIATION: b3945</html:p>
9375 <html:p>PROTEIN_ASSOCIATION: GldA</html:p>
9376 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
9377 <html:p>PROTEIN_CLASS: 1.1.1.6</html:p>
9378 </notes>
9379 <listOfReactants>
9380 <speciesReference species="M_glyc_c" stoichiometry="1.000000"/>
9381 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
9382 </listOfReactants>
9383 <listOfProducts>
9384 <speciesReference species="M_dha_c" stoichiometry="1.000000"/>
9385 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9386 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
9387 </listOfProducts>
9388 </reaction>
9389 <reaction id="R_GLYCK" name="R_glycerate_kinase" reversible="false">
9390 <notes>
9391 <html:p>GENE_ASSOCIATION: ( b0514 or b3124 )</html:p>
9392 <html:p>PROTEIN_ASSOCIATION: ( GlxK ) or ( GarK )</html:p>
9393 <html:p>SUBSYSTEM: S_Glyoxylate_Metabolism</html:p>
9394 <html:p>PROTEIN_CLASS: 2.7.1.31</html:p>
9395 </notes>
9396 <listOfReactants>
9397 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
9398 <speciesReference species="M_glyc_R_c" stoichiometry="1.000000"/>
9399 </listOfReactants>
9400 <listOfProducts>
9401 <speciesReference species="M_3pg_c" stoichiometry="1.000000"/>
9402 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
9403 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9404 </listOfProducts>
9405 </reaction>
9406 <reaction id="R_GLYCL" name="R_Glycine_Cleavage_System" reversible="false">
9407 <notes>
9408 <html:p>GENE_ASSOCIATION: ( b2904 and b2903 and b2905 and b0116 )</html:p>
9409 <html:p>PROTEIN_ASSOCIATION: ( GcvH and GcvP and GcvT and LpdA )</html:p>
9410 <html:p>SUBSYSTEM: S_Folate_Metabolism</html:p>
9411 <html:p>PROTEIN_CLASS: </html:p>
9412 </notes>
9413 <listOfReactants>
9414 <speciesReference species="M_gly_c" stoichiometry="1.000000"/>
9415 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
9416 <speciesReference species="M_thf_c" stoichiometry="1.000000"/>
9417 </listOfReactants>
9418 <listOfProducts>
9419 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
9420 <speciesReference species="M_mlthf_c" stoichiometry="1.000000"/>
9421 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
9422 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
9423 </listOfProducts>
9424 </reaction>
9425 <reaction id="R_GLYCLTDx" name="R_Glycolate_dehydrogenase__NAD_" reversible="false">
9426 <notes>
9427 <html:p>GENE_ASSOCIATION: ( b3553 or b1033 )</html:p>
9428 <html:p>PROTEIN_ASSOCIATION: ( YiaE ) or ( YcdW )</html:p>
9429 <html:p>SUBSYSTEM: S_Glyoxylate_Metabolism</html:p>
9430 <html:p>PROTEIN_CLASS: </html:p>
9431 </notes>
9432 <listOfReactants>
9433 <speciesReference species="M_glx_c" stoichiometry="1.000000"/>
9434 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9435 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
9436 </listOfReactants>
9437 <listOfProducts>
9438 <speciesReference species="M_glyclt_c" stoichiometry="1.000000"/>
9439 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
9440 </listOfProducts>
9441 </reaction>
9442 <reaction id="R_GLYCLTDy" name="R_Glycolate_dehydrogenase__NADP_" reversible="false">
9443 <notes>
9444 <html:p>GENE_ASSOCIATION: ( b1033 or b3553 )</html:p>
9445 <html:p>PROTEIN_ASSOCIATION: ( YcdW ) or ( YiaE )</html:p>
9446 <html:p>SUBSYSTEM: S_Glyoxylate_Metabolism</html:p>
9447 <html:p>PROTEIN_CLASS: 1.1.1.26</html:p>
9448 </notes>
9449 <listOfReactants>
9450 <speciesReference species="M_glx_c" stoichiometry="1.000000"/>
9451 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9452 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
9453 </listOfReactants>
9454 <listOfProducts>
9455 <speciesReference species="M_glyclt_c" stoichiometry="1.000000"/>
9456 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
9457 </listOfProducts>
9458 </reaction>
9459 <reaction id="R_GLYCLTt2r" name="R_glycolate_transport_via_proton_symport__reversible" reversible="true">
9460 <notes>
9461 <html:p>GENE_ASSOCIATION: ( b3603 or b2975 )</html:p>
9462 <html:p>PROTEIN_ASSOCIATION: ( LldP ) or ( GlcA )</html:p>
9463 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
9464 <html:p>PROTEIN_CLASS: </html:p>
9465 </notes>
9466 <listOfReactants>
9467 <speciesReference species="M_glyclt_e" stoichiometry="1.000000"/>
9468 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
9469 </listOfReactants>
9470 <listOfProducts>
9471 <speciesReference species="M_glyclt_c" stoichiometry="1.000000"/>
9472 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9473 </listOfProducts>
9474 </reaction>
9475 <reaction id="R_GLYCTO2" name="R_Glycolate_oxidase" reversible="false">
9476 <notes>
9477 <html:p>GENE_ASSOCIATION: ( b2978 and b2979 )</html:p>
9478 <html:p>PROTEIN_ASSOCIATION: GlcDF</html:p>
9479 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
9480 <html:p>PROTEIN_CLASS: </html:p>
9481 </notes>
9482 <listOfReactants>
9483 <speciesReference species="M_glyclt_c" stoichiometry="1.000000"/>
9484 <speciesReference species="M_q8_c" stoichiometry="1.000000"/>
9485 </listOfReactants>
9486 <listOfProducts>
9487 <speciesReference species="M_glx_c" stoichiometry="1.000000"/>
9488 <speciesReference species="M_q8h2_c" stoichiometry="1.000000"/>
9489 </listOfProducts>
9490 </reaction>
9491 <reaction id="R_GLYCTO3" name="R_Glycolate_oxidase" reversible="false">
9492 <notes>
9493 <html:p>GENE_ASSOCIATION: ( b2978 and b2979 )</html:p>
9494 <html:p>PROTEIN_ASSOCIATION: GlcDF</html:p>
9495 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
9496 <html:p>PROTEIN_CLASS: </html:p>
9497 </notes>
9498 <listOfReactants>
9499 <speciesReference species="M_glyclt_c" stoichiometry="1.000000"/>
9500 <speciesReference species="M_mqn8_c" stoichiometry="1.000000"/>
9501 </listOfReactants>
9502 <listOfProducts>
9503 <speciesReference species="M_glx_c" stoichiometry="1.000000"/>
9504 <speciesReference species="M_mql8_c" stoichiometry="1.000000"/>
9505 </listOfProducts>
9506 </reaction>
9507 <reaction id="R_GLYCTO4" name="R_Glycolate_oxidase" reversible="false">
9508 <notes>
9509 <html:p>GENE_ASSOCIATION: ( b2978 and b2979 )</html:p>
9510 <html:p>PROTEIN_ASSOCIATION: GlcDF</html:p>
9511 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
9512 <html:p>PROTEIN_CLASS: </html:p>
9513 </notes>
9514 <listOfReactants>
9515 <speciesReference species="M_2dmmq8_c" stoichiometry="1.000000"/>
9516 <speciesReference species="M_glyclt_c" stoichiometry="1.000000"/>
9517 </listOfReactants>
9518 <listOfProducts>
9519 <speciesReference species="M_2dmmql8_c" stoichiometry="1.000000"/>
9520 <speciesReference species="M_glx_c" stoichiometry="1.000000"/>
9521 </listOfProducts>
9522 </reaction>
9523 <reaction id="R_GLYCt" name="R_glycerol_transport_via_channel" reversible="true">
9524 <notes>
9525 <html:p>GENE_ASSOCIATION: b3927</html:p>
9526 <html:p>PROTEIN_ASSOCIATION: GlpF</html:p>
9527 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
9528 <html:p>PROTEIN_CLASS: </html:p>
9529 </notes>
9530 <listOfReactants>
9531 <speciesReference species="M_glyc_c" stoichiometry="1.000000"/>
9532 </listOfReactants>
9533 <listOfProducts>
9534 <speciesReference species="M_glyc_e" stoichiometry="1.000000"/>
9535 </listOfProducts>
9536 </reaction>
9537 <reaction id="R_GLYK" name="R_glycerol_kinase" reversible="false">
9538 <notes>
9539 <html:p>GENE_ASSOCIATION: b3926</html:p>
9540 <html:p>PROTEIN_ASSOCIATION: GlpK</html:p>
9541 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
9542 <html:p>PROTEIN_CLASS: 2.7.1.30</html:p>
9543 </notes>
9544 <listOfReactants>
9545 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
9546 <speciesReference species="M_glyc_c" stoichiometry="1.000000"/>
9547 </listOfReactants>
9548 <listOfProducts>
9549 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
9550 <speciesReference species="M_glyc3p_c" stoichiometry="1.000000"/>
9551 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9552 </listOfProducts>
9553 </reaction>
9554 <reaction id="R_GLYOX" name="R_hydroxyacylglutathione_hydrolase" reversible="false">
9555 <notes>
9556 <html:p>GENE_ASSOCIATION: b0212</html:p>
9557 <html:p>PROTEIN_ASSOCIATION: GloB</html:p>
9558 <html:p>SUBSYSTEM: S_Methylglyoxal_Metabolism</html:p>
9559 <html:p>PROTEIN_CLASS: 3.1.2.6</html:p>
9560 </notes>
9561 <listOfReactants>
9562 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
9563 <speciesReference species="M_lgt_S_c" stoichiometry="1.000000"/>
9564 </listOfReactants>
9565 <listOfProducts>
9566 <speciesReference species="M_gthrd_c" stoichiometry="1.000000"/>
9567 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9568 <speciesReference species="M_lac_D_c" stoichiometry="1.000000"/>
9569 </listOfProducts>
9570 </reaction>
9571 <reaction id="R_GLYt2r" name="R_glycine_reversible_transport_via_proton_symport" reversible="true">
9572 <notes>
9573 <html:p>GENE_ASSOCIATION: ( b4208 or b1801 or b0007 )</html:p>
9574 <html:p>PROTEIN_ASSOCIATION: ( CycAec ) or ( YeaV ) or ( YaaJ )</html:p>
9575 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
9576 <html:p>PROTEIN_CLASS: </html:p>
9577 </notes>
9578 <listOfReactants>
9579 <speciesReference species="M_gly_e" stoichiometry="1.000000"/>
9580 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
9581 </listOfReactants>
9582 <listOfProducts>
9583 <speciesReference species="M_gly_c" stoichiometry="1.000000"/>
9584 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9585 </listOfProducts>
9586 </reaction>
9587 <reaction id="R_GMAND" name="R_GDP_D_mannose_dehydratase" reversible="false">
9588 <notes>
9589 <html:p>GENE_ASSOCIATION: b2053</html:p>
9590 <html:p>PROTEIN_ASSOCIATION: Gmd</html:p>
9591 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
9592 <html:p>PROTEIN_CLASS: 4.2.1.47</html:p>
9593 </notes>
9594 <listOfReactants>
9595 <speciesReference species="M_gdpmann_c" stoichiometry="1.000000"/>
9596 </listOfReactants>
9597 <listOfProducts>
9598 <speciesReference species="M_gdpddman_c" stoichiometry="1.000000"/>
9599 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
9600 </listOfProducts>
9601 </reaction>
9602 <reaction id="R_GMHEPAT" name="R_D_glycero_D_manno_hepose_1_phosphate_adenyltransferase" reversible="false">
9603 <notes>
9604 <html:p>GENE_ASSOCIATION: b3052</html:p>
9605 <html:p>PROTEIN_ASSOCIATION: RfaEec</html:p>
9606 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
9607 <html:p>PROTEIN_CLASS: </html:p>
9608 </notes>
9609 <listOfReactants>
9610 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
9611 <speciesReference species="M_gmhep1p_c" stoichiometry="1.000000"/>
9612 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9613 </listOfReactants>
9614 <listOfProducts>
9615 <speciesReference species="M_adphep_DD_c" stoichiometry="1.000000"/>
9616 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
9617 </listOfProducts>
9618 </reaction>
9619 <reaction id="R_GMHEPK" name="R_D_glycero_D_manno_heptose_7_phosphate_kinase" reversible="false">
9620 <notes>
9621 <html:p>GENE_ASSOCIATION: b3052</html:p>
9622 <html:p>PROTEIN_ASSOCIATION: RfaEec</html:p>
9623 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
9624 <html:p>PROTEIN_CLASS: </html:p>
9625 </notes>
9626 <listOfReactants>
9627 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
9628 <speciesReference species="M_gmhep7p_c" stoichiometry="1.000000"/>
9629 </listOfReactants>
9630 <listOfProducts>
9631 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
9632 <speciesReference species="M_gmhep17bp_c" stoichiometry="1.000000"/>
9633 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9634 </listOfProducts>
9635 </reaction>
9636 <reaction id="R_GMHEPPA" name="R_D_glycero_D_manno_heptose_1_7_bisphosphate_phosphatase" reversible="false">
9637 <notes>
9638 <html:p>GENE_ASSOCIATION: b0200</html:p>
9639 <html:p>PROTEIN_ASSOCIATION: GmhB</html:p>
9640 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
9641 <html:p>PROTEIN_CLASS: </html:p>
9642 </notes>
9643 <listOfReactants>
9644 <speciesReference species="M_gmhep17bp_c" stoichiometry="1.000000"/>
9645 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
9646 </listOfReactants>
9647 <listOfProducts>
9648 <speciesReference species="M_gmhep1p_c" stoichiometry="1.000000"/>
9649 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
9650 </listOfProducts>
9651 </reaction>
9652 <reaction id="R_GMPR" name="R_GMP_reductase" reversible="false">
9653 <notes>
9654 <html:p>GENE_ASSOCIATION: b0104</html:p>
9655 <html:p>PROTEIN_ASSOCIATION: GuaC</html:p>
9656 <html:p>SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis</html:p>
9657 <html:p>PROTEIN_CLASS: 1.7.1.7</html:p>
9658 </notes>
9659 <listOfReactants>
9660 <speciesReference species="M_gmp_c" stoichiometry="1.000000"/>
9661 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
9662 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
9663 </listOfReactants>
9664 <listOfProducts>
9665 <speciesReference species="M_imp_c" stoichiometry="1.000000"/>
9666 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
9667 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
9668 </listOfProducts>
9669 </reaction>
9670 <reaction id="R_GMPS2" name="R_GMP_synthase" reversible="false">
9671 <notes>
9672 <html:p>GENE_ASSOCIATION: b2507</html:p>
9673 <html:p>PROTEIN_ASSOCIATION: GuaA</html:p>
9674 <html:p>SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis</html:p>
9675 <html:p>PROTEIN_CLASS: 6.3.5.2</html:p>
9676 </notes>
9677 <listOfReactants>
9678 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
9679 <speciesReference species="M_gln_L_c" stoichiometry="1.000000"/>
9680 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
9681 <speciesReference species="M_xmp_c" stoichiometry="1.000000"/>
9682 </listOfReactants>
9683 <listOfProducts>
9684 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
9685 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
9686 <speciesReference species="M_gmp_c" stoichiometry="1.000000"/>
9687 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
9688 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
9689 </listOfProducts>
9690 </reaction>
9691 <reaction id="R_GND" name="R_phosphogluconate_dehydrogenase" reversible="false">
9692 <notes>
9693 <html:p>GENE_ASSOCIATION: b2029</html:p>
9694 <html:p>PROTEIN_ASSOCIATION: Gnd</html:p>
9695 <html:p>SUBSYSTEM: S_Pentose_Phosphate_Pathway</html:p>
9696 <html:p>PROTEIN_CLASS: 1.1.1.44</html:p>
9697 </notes>
9698 <listOfReactants>
9699 <speciesReference species="M_6pgc_c" stoichiometry="1.000000"/>
9700 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
9701 </listOfReactants>
9702 <listOfProducts>
9703 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
9704 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
9705 <speciesReference species="M_ru5p_D_c" stoichiometry="1.000000"/>
9706 </listOfProducts>
9707 </reaction>
9708 <reaction id="R_GNK" name="R_gluconokinase" reversible="false">
9709 <notes>
9710 <html:p>GENE_ASSOCIATION: ( b4268 or b3437 )</html:p>
9711 <html:p>PROTEIN_ASSOCIATION: ( IdnK ) or ( GntK )</html:p>
9712 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
9713 <html:p>PROTEIN_CLASS: 2.7.1.12</html:p>
9714 </notes>
9715 <listOfReactants>
9716 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
9717 <speciesReference species="M_glcn_c" stoichiometry="1.000000"/>
9718 </listOfReactants>
9719 <listOfProducts>
9720 <speciesReference species="M_6pgc_c" stoichiometry="1.000000"/>
9721 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
9722 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9723 </listOfProducts>
9724 </reaction>
9725 <reaction id="R_GOFUCR" name="R_GDP_4_oxo_L_fucose_reductase" reversible="false">
9726 <notes>
9727 <html:p>GENE_ASSOCIATION: b2052</html:p>
9728 <html:p>PROTEIN_ASSOCIATION: Fcl</html:p>
9729 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
9730 <html:p>PROTEIN_CLASS: </html:p>
9731 </notes>
9732 <listOfReactants>
9733 <speciesReference species="M_gdpofuc_c" stoichiometry="1.000000"/>
9734 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9735 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
9736 </listOfReactants>
9737 <listOfProducts>
9738 <speciesReference species="M_gdpfuc_c" stoichiometry="1.000000"/>
9739 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
9740 </listOfProducts>
9741 </reaction>
9742 <reaction id="R_GP4GH" name="R_Gp4G_hydrolase" reversible="false">
9743 <notes>
9744 <html:p>GENE_ASSOCIATION: b0049</html:p>
9745 <html:p>PROTEIN_ASSOCIATION: ApaH</html:p>
9746 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
9747 <html:p>PROTEIN_CLASS: </html:p>
9748 </notes>
9749 <listOfReactants>
9750 <speciesReference species="M_gp4g_c" stoichiometry="1.000000"/>
9751 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
9752 </listOfReactants>
9753 <listOfProducts>
9754 <speciesReference species="M_gdp_c" stoichiometry="2.000000"/>
9755 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
9756 </listOfProducts>
9757 </reaction>
9758 <reaction id="R_GPDDA1" name="R_Glycerophosphodiester_phosphodiesterase__Glycerophosphocholine_" reversible="false">
9759 <notes>
9760 <html:p>GENE_ASSOCIATION: b2239</html:p>
9761 <html:p>PROTEIN_ASSOCIATION: GlpQ</html:p>
9762 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
9763 <html:p>PROTEIN_CLASS: 3.1.4.46</html:p>
9764 </notes>
9765 <listOfReactants>
9766 <speciesReference species="M_g3pc_c" stoichiometry="1.000000"/>
9767 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
9768 </listOfReactants>
9769 <listOfProducts>
9770 <speciesReference species="M_chol_c" stoichiometry="1.000000"/>
9771 <speciesReference species="M_glyc3p_c" stoichiometry="1.000000"/>
9772 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9773 </listOfProducts>
9774 </reaction>
9775 <reaction id="R_GPDDA2" name="R_Glycerophosphodiester_phosphodiesterase__Glycerophosphoethanolamine_" reversible="false">
9776 <notes>
9777 <html:p>GENE_ASSOCIATION: b2239</html:p>
9778 <html:p>PROTEIN_ASSOCIATION: GlpQ</html:p>
9779 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
9780 <html:p>PROTEIN_CLASS: 3.1.4.46</html:p>
9781 </notes>
9782 <listOfReactants>
9783 <speciesReference species="M_g3pe_c" stoichiometry="1.000000"/>
9784 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
9785 </listOfReactants>
9786 <listOfProducts>
9787 <speciesReference species="M_etha_c" stoichiometry="1.000000"/>
9788 <speciesReference species="M_glyc3p_c" stoichiometry="1.000000"/>
9789 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9790 </listOfProducts>
9791 </reaction>
9792 <reaction id="R_GPDDA3" name="R_Glycerophosphodiester_phosphodiesterase__Glycerophosphoserine_" reversible="false">
9793 <notes>
9794 <html:p>GENE_ASSOCIATION: b2239</html:p>
9795 <html:p>PROTEIN_ASSOCIATION: GlpQ</html:p>
9796 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
9797 <html:p>PROTEIN_CLASS: 3.1.4.46</html:p>
9798 </notes>
9799 <listOfReactants>
9800 <speciesReference species="M_g3ps_c" stoichiometry="1.000000"/>
9801 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
9802 </listOfReactants>
9803 <listOfProducts>
9804 <speciesReference species="M_glyc3p_c" stoichiometry="1.000000"/>
9805 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9806 <speciesReference species="M_ser_L_c" stoichiometry="1.000000"/>
9807 </listOfProducts>
9808 </reaction>
9809 <reaction id="R_GPDDA4" name="R_Glycerophosphodiester_phosphodiesterase__Glycerophosphoglycerol_" reversible="false">
9810 <notes>
9811 <html:p>GENE_ASSOCIATION: b2239</html:p>
9812 <html:p>PROTEIN_ASSOCIATION: GlpQ</html:p>
9813 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
9814 <html:p>PROTEIN_CLASS: 3.1.4.46</html:p>
9815 </notes>
9816 <listOfReactants>
9817 <speciesReference species="M_g3pg_c" stoichiometry="1.000000"/>
9818 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
9819 </listOfReactants>
9820 <listOfProducts>
9821 <speciesReference species="M_glyc_c" stoichiometry="1.000000"/>
9822 <speciesReference species="M_glyc3p_c" stoichiometry="1.000000"/>
9823 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9824 </listOfProducts>
9825 </reaction>
9826 <reaction id="R_GPDDA5" name="R_Glycerophosphodiester_phosphodiesterase__Glycerophosphoinositol_" reversible="false">
9827 <notes>
9828 <html:p>GENE_ASSOCIATION: b2239</html:p>
9829 <html:p>PROTEIN_ASSOCIATION: GlpQ</html:p>
9830 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
9831 <html:p>PROTEIN_CLASS: 3.1.4.46</html:p>
9832 </notes>
9833 <listOfReactants>
9834 <speciesReference species="M_g3pi_c" stoichiometry="1.000000"/>
9835 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
9836 </listOfReactants>
9837 <listOfProducts>
9838 <speciesReference species="M_glyc3p_c" stoichiometry="1.000000"/>
9839 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9840 <speciesReference species="M_inost_c" stoichiometry="1.000000"/>
9841 </listOfProducts>
9842 </reaction>
9843 <reaction id="R_GRTT" name="R_geranyltranstransferase" reversible="false">
9844 <notes>
9845 <html:p>GENE_ASSOCIATION: b0421</html:p>
9846 <html:p>PROTEIN_ASSOCIATION: IspA</html:p>
9847 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
9848 <html:p>PROTEIN_CLASS: 2.5.1.10</html:p>
9849 </notes>
9850 <listOfReactants>
9851 <speciesReference species="M_grdp_c" stoichiometry="1.000000"/>
9852 <speciesReference species="M_ipdp_c" stoichiometry="1.000000"/>
9853 </listOfReactants>
9854 <listOfProducts>
9855 <speciesReference species="M_frdp_c" stoichiometry="1.000000"/>
9856 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
9857 </listOfProducts>
9858 </reaction>
9859 <reaction id="R_GSNK" name="R_guanosine_kinase" reversible="false">
9860 <notes>
9861 <html:p>GENE_ASSOCIATION: b0477</html:p>
9862 <html:p>PROTEIN_ASSOCIATION: Gsk</html:p>
9863 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
9864 <html:p>PROTEIN_CLASS: </html:p>
9865 </notes>
9866 <listOfReactants>
9867 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
9868 <speciesReference species="M_gsn_c" stoichiometry="1.000000"/>
9869 </listOfReactants>
9870 <listOfProducts>
9871 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
9872 <speciesReference species="M_gmp_c" stoichiometry="1.000000"/>
9873 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9874 </listOfProducts>
9875 </reaction>
9876 <reaction id="R_GSNt2" name="R_guanosine_transport_in_via_proton_symport" reversible="false">
9877 <notes>
9878 <html:p>GENE_ASSOCIATION: b2964</html:p>
9879 <html:p>PROTEIN_ASSOCIATION: NupG</html:p>
9880 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
9881 <html:p>PROTEIN_CLASS: </html:p>
9882 </notes>
9883 <listOfReactants>
9884 <speciesReference species="M_gsn_e" stoichiometry="1.000000"/>
9885 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
9886 </listOfReactants>
9887 <listOfProducts>
9888 <speciesReference species="M_gsn_c" stoichiometry="1.000000"/>
9889 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9890 </listOfProducts>
9891 </reaction>
9892 <reaction id="R_GSPMDA" name="R_Glutathionylspermidine_amidase" reversible="false">
9893 <notes>
9894 <html:p>GENE_ASSOCIATION: b2988</html:p>
9895 <html:p>PROTEIN_ASSOCIATION: Gsp</html:p>
9896 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
9897 <html:p>PROTEIN_CLASS: 3.5.1.78</html:p>
9898 </notes>
9899 <listOfReactants>
9900 <speciesReference species="M_gtspmd_c" stoichiometry="1.000000"/>
9901 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
9902 </listOfReactants>
9903 <listOfProducts>
9904 <speciesReference species="M_gthrd_c" stoichiometry="1.000000"/>
9905 <speciesReference species="M_spmd_c" stoichiometry="1.000000"/>
9906 </listOfProducts>
9907 </reaction>
9908 <reaction id="R_GSPMDS" name="R_Glutathionylspermidine_synthetase" reversible="false">
9909 <notes>
9910 <html:p>GENE_ASSOCIATION: b2988</html:p>
9911 <html:p>PROTEIN_ASSOCIATION: Gsp</html:p>
9912 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
9913 <html:p>PROTEIN_CLASS: 6.3.1.8</html:p>
9914 </notes>
9915 <listOfReactants>
9916 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
9917 <speciesReference species="M_gthrd_c" stoichiometry="1.000000"/>
9918 <speciesReference species="M_spmd_c" stoichiometry="1.000000"/>
9919 </listOfReactants>
9920 <listOfProducts>
9921 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
9922 <speciesReference species="M_gtspmd_c" stoichiometry="1.000000"/>
9923 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9924 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
9925 </listOfProducts>
9926 </reaction>
9927 <reaction id="R_GTHOr" name="R_glutathione_oxidoreductase" reversible="true">
9928 <notes>
9929 <html:p>GENE_ASSOCIATION: b3500</html:p>
9930 <html:p>PROTEIN_ASSOCIATION: GAPOR</html:p>
9931 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
9932 <html:p>PROTEIN_CLASS: 1.8.1.7</html:p>
9933 </notes>
9934 <listOfReactants>
9935 <speciesReference species="M_gthox_c" stoichiometry="1.000000"/>
9936 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9937 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
9938 </listOfReactants>
9939 <listOfProducts>
9940 <speciesReference species="M_gthrd_c" stoichiometry="2.000000"/>
9941 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
9942 </listOfProducts>
9943 </reaction>
9944 <reaction id="R_GTHS" name="R_glutathione_synthetase" reversible="false">
9945 <notes>
9946 <html:p>GENE_ASSOCIATION: b2947</html:p>
9947 <html:p>PROTEIN_ASSOCIATION: GshB</html:p>
9948 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
9949 <html:p>PROTEIN_CLASS: 6.3.2.3</html:p>
9950 </notes>
9951 <listOfReactants>
9952 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
9953 <speciesReference species="M_glucys_c" stoichiometry="1.000000"/>
9954 <speciesReference species="M_gly_c" stoichiometry="1.000000"/>
9955 </listOfReactants>
9956 <listOfProducts>
9957 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
9958 <speciesReference species="M_gthrd_c" stoichiometry="1.000000"/>
9959 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
9960 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
9961 </listOfProducts>
9962 </reaction>
9963 <reaction id="R_GTPCII2" name="R_GTP_cyclohydrolase_II__25drapp_" reversible="false">
9964 <notes>
9965 <html:p>GENE_ASSOCIATION: b1277</html:p>
9966 <html:p>PROTEIN_ASSOCIATION: RibA</html:p>
9967 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
9968 <html:p>PROTEIN_CLASS: </html:p>
9969 </notes>
9970 <listOfReactants>
9971 <speciesReference species="M_gtp_c" stoichiometry="1.000000"/>
9972 <speciesReference species="M_h2o_c" stoichiometry="3.000000"/>
9973 </listOfReactants>
9974 <listOfProducts>
9975 <speciesReference species="M_25drapp_c" stoichiometry="1.000000"/>
9976 <speciesReference species="M_for_c" stoichiometry="1.000000"/>
9977 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
9978 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
9979 </listOfProducts>
9980 </reaction>
9981 <reaction id="R_GTPCI" name="R_GTP_cyclohydrolase_I" reversible="false">
9982 <notes>
9983 <html:p>GENE_ASSOCIATION: b2153</html:p>
9984 <html:p>PROTEIN_ASSOCIATION: FolE</html:p>
9985 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
9986 <html:p>PROTEIN_CLASS: 3.5.4.16</html:p>
9987 </notes>
9988 <listOfReactants>
9989 <speciesReference species="M_gtp_c" stoichiometry="1.000000"/>
9990 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
9991 </listOfReactants>
9992 <listOfProducts>
9993 <speciesReference species="M_ahdt_c" stoichiometry="1.000000"/>
9994 <speciesReference species="M_for_c" stoichiometry="1.000000"/>
9995 </listOfProducts>
9996 </reaction>
9997 <reaction id="R_GUAD" name="R_guanine_deaminase" reversible="false">
9998 <notes>
9999 <html:p>GENE_ASSOCIATION: b2883</html:p>
10000 <html:p>PROTEIN_ASSOCIATION: YgfP</html:p>
10001 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
10002 <html:p>PROTEIN_CLASS: 3.5.4.3</html:p>
10003 </notes>
10004 <listOfReactants>
10005 <speciesReference species="M_gua_c" stoichiometry="1.000000"/>
10006 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10007 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
10008 </listOfReactants>
10009 <listOfProducts>
10010 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
10011 <speciesReference species="M_xan_c" stoichiometry="1.000000"/>
10012 </listOfProducts>
10013 </reaction>
10014 <reaction id="R_GUAPRT" name="R_guanine_phosphoribosyltransferase" reversible="false">
10015 <notes>
10016 <html:p>GENE_ASSOCIATION: ( b0238 or b0125 )</html:p>
10017 <html:p>PROTEIN_ASSOCIATION: ( Gpt ) or ( Hpt )</html:p>
10018 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
10019 <html:p>PROTEIN_CLASS: 2.4.2.8</html:p>
10020 </notes>
10021 <listOfReactants>
10022 <speciesReference species="M_gua_c" stoichiometry="1.000000"/>
10023 <speciesReference species="M_prpp_c" stoichiometry="1.000000"/>
10024 </listOfReactants>
10025 <listOfProducts>
10026 <speciesReference species="M_gmp_c" stoichiometry="1.000000"/>
10027 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
10028 </listOfProducts>
10029 </reaction>
10030 <reaction id="R_GUAt" name="R_Guanine_transport" reversible="true">
10031 <notes>
10032 <html:p>GENE_ASSOCIATION: </html:p>
10033 <html:p>PROTEIN_ASSOCIATION: </html:p>
10034 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
10035 <html:p>PROTEIN_CLASS: </html:p>
10036 </notes>
10037 <listOfReactants>
10038 <speciesReference species="M_gua_e" stoichiometry="1.000000"/>
10039 </listOfReactants>
10040 <listOfProducts>
10041 <speciesReference species="M_gua_c" stoichiometry="1.000000"/>
10042 </listOfProducts>
10043 </reaction>
10044 <reaction id="R_GUAt2" name="R_guanine_transport_in_via_proton_symport" reversible="false">
10045 <notes>
10046 <html:p>GENE_ASSOCIATION: b3654</html:p>
10047 <html:p>PROTEIN_ASSOCIATION: YicE</html:p>
10048 <html:p>SUBSYSTEM: S_Putative_Transporters</html:p>
10049 <html:p>PROTEIN_CLASS: </html:p>
10050 </notes>
10051 <listOfReactants>
10052 <speciesReference species="M_gua_e" stoichiometry="1.000000"/>
10053 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
10054 </listOfReactants>
10055 <listOfProducts>
10056 <speciesReference species="M_gua_c" stoichiometry="1.000000"/>
10057 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10058 </listOfProducts>
10059 </reaction>
10060 <reaction id="R_GUI1" name="R_glucuronate_isomerase__D_glucuronate_" reversible="true">
10061 <notes>
10062 <html:p>GENE_ASSOCIATION: b3092</html:p>
10063 <html:p>PROTEIN_ASSOCIATION: UxaC</html:p>
10064 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
10065 <html:p>PROTEIN_CLASS: 5.3.1.12</html:p>
10066 </notes>
10067 <listOfReactants>
10068 <speciesReference species="M_glcur_c" stoichiometry="1.000000"/>
10069 </listOfReactants>
10070 <listOfProducts>
10071 <speciesReference species="M_fruur_c" stoichiometry="1.000000"/>
10072 </listOfProducts>
10073 </reaction>
10074 <reaction id="R_GUI2" name="R_glucuronate_isomerase__D_galacturonate_" reversible="true">
10075 <notes>
10076 <html:p>GENE_ASSOCIATION: b3092</html:p>
10077 <html:p>PROTEIN_ASSOCIATION: UxaC</html:p>
10078 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
10079 <html:p>PROTEIN_CLASS: 5.3.1.12</html:p>
10080 </notes>
10081 <listOfReactants>
10082 <speciesReference species="M_galur_c" stoichiometry="1.000000"/>
10083 </listOfReactants>
10084 <listOfProducts>
10085 <speciesReference species="M_tagur_c" stoichiometry="1.000000"/>
10086 </listOfProducts>
10087 </reaction>
10088 <reaction id="R_H2Ot" name="R_H2O_transport_via_diffusion" reversible="true">
10089 <notes>
10090 <html:p>GENE_ASSOCIATION: </html:p>
10091 <html:p>PROTEIN_ASSOCIATION: </html:p>
10092 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
10093 <html:p>PROTEIN_CLASS: </html:p>
10094 </notes>
10095 <listOfReactants>
10096 <speciesReference species="M_h2o_e" stoichiometry="1.000000"/>
10097 </listOfReactants>
10098 <listOfProducts>
10099 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
10100 </listOfProducts>
10101 </reaction>
10102 <reaction id="R_HBZOPT" name="R_Hydroxybenzoate_octaprenyltransferase" reversible="false">
10103 <notes>
10104 <html:p>GENE_ASSOCIATION: b4040</html:p>
10105 <html:p>PROTEIN_ASSOCIATION: UbiA</html:p>
10106 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
10107 <html:p>PROTEIN_CLASS: </html:p>
10108 </notes>
10109 <listOfReactants>
10110 <speciesReference species="M_4hbz_c" stoichiometry="1.000000"/>
10111 <speciesReference species="M_octdp_c" stoichiometry="1.000000"/>
10112 </listOfReactants>
10113 <listOfProducts>
10114 <speciesReference species="M_3ophb_c" stoichiometry="1.000000"/>
10115 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
10116 </listOfProducts>
10117 </reaction>
10118 <reaction id="R_HCINNMt2r" name="R_3_hydroxycinnamic_acid_transport_via_proton_symport__reversible" reversible="true">
10119 <notes>
10120 <html:p>GENE_ASSOCIATION: b0353</html:p>
10121 <html:p>PROTEIN_ASSOCIATION: MhpT</html:p>
10122 <html:p>SUBSYSTEM: S_Putative_Transporters</html:p>
10123 <html:p>PROTEIN_CLASS: </html:p>
10124 </notes>
10125 <listOfReactants>
10126 <speciesReference species="M_3hcinnm_e" stoichiometry="1.000000"/>
10127 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
10128 </listOfReactants>
10129 <listOfProducts>
10130 <speciesReference species="M_3hcinnm_c" stoichiometry="1.000000"/>
10131 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10132 </listOfProducts>
10133 </reaction>
10134 <reaction id="R_HCO3E" name="R_HCO3_equilibration_reaction" reversible="true">
10135 <notes>
10136 <html:p>GENE_ASSOCIATION: ( b0339 or b0126 )</html:p>
10137 <html:p>PROTEIN_ASSOCIATION: ( CynT ) or ( YadF )</html:p>
10138 <html:p>SUBSYSTEM: S_Unassigned</html:p>
10139 <html:p>PROTEIN_CLASS: 4.2.1.1</html:p>
10140 </notes>
10141 <listOfReactants>
10142 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
10143 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
10144 </listOfReactants>
10145 <listOfProducts>
10146 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10147 <speciesReference species="M_hco3_c" stoichiometry="1.000000"/>
10148 </listOfProducts>
10149 </reaction>
10150 <reaction id="R_HDCAt2" name="R_Hexadecanoate_transport_via_proton_symport" reversible="false">
10151 <notes>
10152 <html:p>GENE_ASSOCIATION: b2344</html:p>
10153 <html:p>PROTEIN_ASSOCIATION: FadL</html:p>
10154 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
10155 <html:p>PROTEIN_CLASS: </html:p>
10156 </notes>
10157 <listOfReactants>
10158 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
10159 <speciesReference species="M_hdca_e" stoichiometry="1.000000"/>
10160 </listOfReactants>
10161 <listOfProducts>
10162 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10163 <speciesReference species="M_hdca_c" stoichiometry="1.000000"/>
10164 </listOfProducts>
10165 </reaction>
10166 <reaction id="R_HEMEOS" name="R_Heme_O_synthase" reversible="false">
10167 <notes>
10168 <html:p>GENE_ASSOCIATION: b0428</html:p>
10169 <html:p>PROTEIN_ASSOCIATION: CyoE</html:p>
10170 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
10171 <html:p>PROTEIN_CLASS: </html:p>
10172 </notes>
10173 <listOfReactants>
10174 <speciesReference species="M_frdp_c" stoichiometry="1.000000"/>
10175 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
10176 <speciesReference species="M_pheme_c" stoichiometry="1.000000"/>
10177 </listOfReactants>
10178 <listOfProducts>
10179 <speciesReference species="M_hemeO_c" stoichiometry="1.000000"/>
10180 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
10181 </listOfProducts>
10182 </reaction>
10183 <reaction id="R_HETZK" name="R_hydroxyethylthiazole_kinase" reversible="false">
10184 <notes>
10185 <html:p>GENE_ASSOCIATION: b2104</html:p>
10186 <html:p>PROTEIN_ASSOCIATION: ThiMec</html:p>
10187 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
10188 <html:p>PROTEIN_CLASS: 2.7.1.50</html:p>
10189 </notes>
10190 <listOfReactants>
10191 <speciesReference species="M_4mhetz_c" stoichiometry="1.000000"/>
10192 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
10193 </listOfReactants>
10194 <listOfProducts>
10195 <speciesReference species="M_4mpetz_c" stoichiometry="1.000000"/>
10196 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
10197 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10198 </listOfProducts>
10199 </reaction>
10200 <reaction id="R_HEX1" name="R_hexokinase__D_glucoseATP_" reversible="false">
10201 <notes>
10202 <html:p>GENE_ASSOCIATION: b2388</html:p>
10203 <html:p>PROTEIN_ASSOCIATION: Glk</html:p>
10204 <html:p>SUBSYSTEM: S_GlycolysisGluconeogenesis</html:p>
10205 <html:p>PROTEIN_CLASS: 2.7.1.1</html:p>
10206 </notes>
10207 <listOfReactants>
10208 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
10209 <speciesReference species="M_glc_D_c" stoichiometry="1.000000"/>
10210 </listOfReactants>
10211 <listOfProducts>
10212 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
10213 <speciesReference species="M_g6p_c" stoichiometry="1.000000"/>
10214 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10215 </listOfProducts>
10216 </reaction>
10217 <reaction id="R_HISTD" name="R_histidinol_dehydrogenase" reversible="false">
10218 <notes>
10219 <html:p>GENE_ASSOCIATION: b2020</html:p>
10220 <html:p>PROTEIN_ASSOCIATION: HisD</html:p>
10221 <html:p>SUBSYSTEM: S_Histidine_Metabolism</html:p>
10222 <html:p>PROTEIN_CLASS: 1.1.1.23</html:p>
10223 </notes>
10224 <listOfReactants>
10225 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
10226 <speciesReference species="M_histd_c" stoichiometry="1.000000"/>
10227 <speciesReference species="M_nad_c" stoichiometry="2.000000"/>
10228 </listOfReactants>
10229 <listOfProducts>
10230 <speciesReference species="M_h_c" stoichiometry="3.000000"/>
10231 <speciesReference species="M_his_L_c" stoichiometry="1.000000"/>
10232 <speciesReference species="M_nadh_c" stoichiometry="2.000000"/>
10233 </listOfProducts>
10234 </reaction>
10235 <reaction id="R_HISTP" name="R_histidinol_phosphatase" reversible="false">
10236 <notes>
10237 <html:p>GENE_ASSOCIATION: b2022</html:p>
10238 <html:p>PROTEIN_ASSOCIATION: HisB</html:p>
10239 <html:p>SUBSYSTEM: S_Histidine_Metabolism</html:p>
10240 <html:p>PROTEIN_CLASS: 3.1.3.15</html:p>
10241 </notes>
10242 <listOfReactants>
10243 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
10244 <speciesReference species="M_hisp_c" stoichiometry="1.000000"/>
10245 </listOfReactants>
10246 <listOfProducts>
10247 <speciesReference species="M_histd_c" stoichiometry="1.000000"/>
10248 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
10249 </listOfProducts>
10250 </reaction>
10251 <reaction id="R_HISabc" name="R_L_histidine_transport_via_ABC_system" reversible="false">
10252 <notes>
10253 <html:p>GENE_ASSOCIATION: ( b2309 and b2307 and b2306 and b2308 )</html:p>
10254 <html:p>PROTEIN_ASSOCIATION: ( HisJ and HisM and HisP and HisQ )</html:p>
10255 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
10256 <html:p>PROTEIN_CLASS: </html:p>
10257 </notes>
10258 <listOfReactants>
10259 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
10260 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
10261 <speciesReference species="M_his_L_e" stoichiometry="1.000000"/>
10262 </listOfReactants>
10263 <listOfProducts>
10264 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
10265 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10266 <speciesReference species="M_his_L_c" stoichiometry="1.000000"/>
10267 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
10268 </listOfProducts>
10269 </reaction>
10270 <reaction id="R_HISt2r" name="R_L_histidine_reversible_transport_via_proton_symport" reversible="true">
10271 <notes>
10272 <html:p>GENE_ASSOCIATION: b0112</html:p>
10273 <html:p>PROTEIN_ASSOCIATION: AroP</html:p>
10274 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
10275 <html:p>PROTEIN_CLASS: </html:p>
10276 </notes>
10277 <listOfReactants>
10278 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
10279 <speciesReference species="M_his_L_e" stoichiometry="1.000000"/>
10280 </listOfReactants>
10281 <listOfProducts>
10282 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10283 <speciesReference species="M_his_L_c" stoichiometry="1.000000"/>
10284 </listOfProducts>
10285 </reaction>
10286 <reaction id="R_HKNDDH" name="R_2_hydroxy_6_ketonona_2_4_dienedioic_acid_hydrolase" reversible="false">
10287 <notes>
10288 <html:p>GENE_ASSOCIATION: b0349</html:p>
10289 <html:p>PROTEIN_ASSOCIATION: MhpC</html:p>
10290 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
10291 <html:p>PROTEIN_CLASS: </html:p>
10292 </notes>
10293 <listOfReactants>
10294 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
10295 <speciesReference species="M_hkndd_c" stoichiometry="1.000000"/>
10296 </listOfReactants>
10297 <listOfProducts>
10298 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
10299 <speciesReference species="M_op4en_c" stoichiometry="1.000000"/>
10300 <speciesReference species="M_succ_c" stoichiometry="1.000000"/>
10301 </listOfProducts>
10302 </reaction>
10303 <reaction id="R_HKNTDH" name="R_2_hydroxy_6_ketononotrienedioate_hydrolase" reversible="false">
10304 <notes>
10305 <html:p>GENE_ASSOCIATION: b0349</html:p>
10306 <html:p>PROTEIN_ASSOCIATION: MhpC</html:p>
10307 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
10308 <html:p>PROTEIN_CLASS: </html:p>
10309 </notes>
10310 <listOfReactants>
10311 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
10312 <speciesReference species="M_hkntd_c" stoichiometry="1.000000"/>
10313 </listOfReactants>
10314 <listOfProducts>
10315 <speciesReference species="M_fum_c" stoichiometry="1.000000"/>
10316 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
10317 <speciesReference species="M_op4en_c" stoichiometry="1.000000"/>
10318 </listOfProducts>
10319 </reaction>
10320 <reaction id="R_HMBS" name="R_hydroxymethylbilane_synthase" reversible="false">
10321 <notes>
10322 <html:p>GENE_ASSOCIATION: b3805</html:p>
10323 <html:p>PROTEIN_ASSOCIATION: HemCec</html:p>
10324 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
10325 <html:p>PROTEIN_CLASS: 4.3.1.8</html:p>
10326 </notes>
10327 <listOfReactants>
10328 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
10329 <speciesReference species="M_ppbng_c" stoichiometry="4.000000"/>
10330 </listOfReactants>
10331 <listOfProducts>
10332 <speciesReference species="M_hmbil_c" stoichiometry="1.000000"/>
10333 <speciesReference species="M_nh4_c" stoichiometry="4.000000"/>
10334 </listOfProducts>
10335 </reaction>
10336 <reaction id="R_HMPK1" name="R_hydroxymethylpyrimidine_kinase__ATP_" reversible="false">
10337 <notes>
10338 <html:p>GENE_ASSOCIATION: ( b2103 or b2418 )</html:p>
10339 <html:p>PROTEIN_ASSOCIATION: ( ThiDec ) or ( PdxK )</html:p>
10340 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
10341 <html:p>PROTEIN_CLASS: 2.7.1.49</html:p>
10342 </notes>
10343 <listOfReactants>
10344 <speciesReference species="M_4ahmmp_c" stoichiometry="1.000000"/>
10345 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
10346 </listOfReactants>
10347 <listOfProducts>
10348 <speciesReference species="M_4ampm_c" stoichiometry="1.000000"/>
10349 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
10350 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10351 </listOfProducts>
10352 </reaction>
10353 <reaction id="R_HOPNTAL" name="R_4_hydroxy_2_oxopentanoate_aldolase" reversible="false">
10354 <notes>
10355 <html:p>GENE_ASSOCIATION: b0352</html:p>
10356 <html:p>PROTEIN_ASSOCIATION: MhpE</html:p>
10357 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
10358 <html:p>PROTEIN_CLASS: </html:p>
10359 </notes>
10360 <listOfReactants>
10361 <speciesReference species="M_4h2opntn_c" stoichiometry="1.000000"/>
10362 </listOfReactants>
10363 <listOfProducts>
10364 <speciesReference species="M_acald_c" stoichiometry="1.000000"/>
10365 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
10366 </listOfProducts>
10367 </reaction>
10368 <reaction id="R_HPPK2" name="R_6_hydroxymethyl_dihydropterin_pyrophosphokinase" reversible="false">
10369 <notes>
10370 <html:p>GENE_ASSOCIATION: b0142</html:p>
10371 <html:p>PROTEIN_ASSOCIATION: FolK</html:p>
10372 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
10373 <html:p>PROTEIN_CLASS: </html:p>
10374 </notes>
10375 <listOfReactants>
10376 <speciesReference species="M_6hmhpt_c" stoichiometry="1.000000"/>
10377 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
10378 </listOfReactants>
10379 <listOfProducts>
10380 <speciesReference species="M_6hmhptpp_c" stoichiometry="1.000000"/>
10381 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
10382 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10383 </listOfProducts>
10384 </reaction>
10385 <reaction id="R_HPPPNDO" name="R_2_3_dihydroxypheylpropionate_1_2_dioxygenase" reversible="false">
10386 <notes>
10387 <html:p>GENE_ASSOCIATION: b0348</html:p>
10388 <html:p>PROTEIN_ASSOCIATION: MhpB</html:p>
10389 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
10390 <html:p>PROTEIN_CLASS: 1.13.11.16</html:p>
10391 </notes>
10392 <listOfReactants>
10393 <speciesReference species="M_dhpppn_c" stoichiometry="1.000000"/>
10394 <speciesReference species="M_o2_c" stoichiometry="1.000000"/>
10395 </listOfReactants>
10396 <listOfProducts>
10397 <speciesReference species="M_hkndd_c" stoichiometry="1.000000"/>
10398 </listOfProducts>
10399 </reaction>
10400 <reaction id="R_HPPPNt2r" name="R_3__3_hydroxyphenyl_propionate_transport_via_proton_symport__reversible" reversible="true">
10401 <notes>
10402 <html:p>GENE_ASSOCIATION: b0353</html:p>
10403 <html:p>PROTEIN_ASSOCIATION: MhpT</html:p>
10404 <html:p>SUBSYSTEM: S_Putative_Transporters</html:p>
10405 <html:p>PROTEIN_CLASS: </html:p>
10406 </notes>
10407 <listOfReactants>
10408 <speciesReference species="M_3hpppn_e" stoichiometry="1.000000"/>
10409 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
10410 </listOfReactants>
10411 <listOfProducts>
10412 <speciesReference species="M_3hpppn_c" stoichiometry="1.000000"/>
10413 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10414 </listOfProducts>
10415 </reaction>
10416 <reaction id="R_HPYRI" name="R_hydroxypyruvate_isomerase" reversible="true">
10417 <notes>
10418 <html:p>GENE_ASSOCIATION: b0508</html:p>
10419 <html:p>PROTEIN_ASSOCIATION: Hyi</html:p>
10420 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
10421 <html:p>PROTEIN_CLASS: 5.3.1.22</html:p>
10422 </notes>
10423 <listOfReactants>
10424 <speciesReference species="M_hpyr_c" stoichiometry="1.000000"/>
10425 </listOfReactants>
10426 <listOfProducts>
10427 <speciesReference species="M_2h3oppan_c" stoichiometry="1.000000"/>
10428 </listOfProducts>
10429 </reaction>
10430 <reaction id="R_HPYRRx" name="R_Hydroxypyruvate_reductase__NADH_" reversible="false">
10431 <notes>
10432 <html:p>GENE_ASSOCIATION: ( b1033 or b3553 )</html:p>
10433 <html:p>PROTEIN_ASSOCIATION: ( YcdW ) or ( YiaE )</html:p>
10434 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
10435 <html:p>PROTEIN_CLASS: </html:p>
10436 </notes>
10437 <listOfReactants>
10438 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10439 <speciesReference species="M_hpyr_c" stoichiometry="1.000000"/>
10440 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
10441 </listOfReactants>
10442 <listOfProducts>
10443 <speciesReference species="M_glyc_R_c" stoichiometry="1.000000"/>
10444 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
10445 </listOfProducts>
10446 </reaction>
10447 <reaction id="R_HPYRRy" name="R_Hydroxypyruvate_reductase__NADPH_" reversible="false">
10448 <notes>
10449 <html:p>GENE_ASSOCIATION: ( b1033 or b3553 )</html:p>
10450 <html:p>PROTEIN_ASSOCIATION: ( YcdW ) or ( YiaE )</html:p>
10451 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
10452 <html:p>PROTEIN_CLASS: </html:p>
10453 </notes>
10454 <listOfReactants>
10455 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10456 <speciesReference species="M_hpyr_c" stoichiometry="1.000000"/>
10457 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
10458 </listOfReactants>
10459 <listOfProducts>
10460 <speciesReference species="M_glyc_R_c" stoichiometry="1.000000"/>
10461 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
10462 </listOfProducts>
10463 </reaction>
10464 <reaction id="R_HSDy" name="R_homoserine_dehydrogenase__NADPH_" reversible="true">
10465 <notes>
10466 <html:p>GENE_ASSOCIATION: ( b3940 or b0002 )</html:p>
10467 <html:p>PROTEIN_ASSOCIATION: ( MetL ) or ( ThrA )</html:p>
10468 <html:p>SUBSYSTEM: S_Threonine_and_Lysine_Metabolism</html:p>
10469 <html:p>PROTEIN_CLASS: 1.1.1.3</html:p>
10470 </notes>
10471 <listOfReactants>
10472 <speciesReference species="M_hom_L_c" stoichiometry="1.000000"/>
10473 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
10474 </listOfReactants>
10475 <listOfProducts>
10476 <speciesReference species="M_aspsa_c" stoichiometry="1.000000"/>
10477 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10478 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
10479 </listOfProducts>
10480 </reaction>
10481 <reaction id="R_HSK" name="R_homoserine_kinase" reversible="false">
10482 <notes>
10483 <html:p>GENE_ASSOCIATION: b0003</html:p>
10484 <html:p>PROTEIN_ASSOCIATION: ThrB</html:p>
10485 <html:p>SUBSYSTEM: S_Threonine_and_Lysine_Metabolism</html:p>
10486 <html:p>PROTEIN_CLASS: 2.7.1.39</html:p>
10487 </notes>
10488 <listOfReactants>
10489 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
10490 <speciesReference species="M_hom_L_c" stoichiometry="1.000000"/>
10491 </listOfReactants>
10492 <listOfProducts>
10493 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
10494 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10495 <speciesReference species="M_phom_c" stoichiometry="1.000000"/>
10496 </listOfProducts>
10497 </reaction>
10498 <reaction id="R_HSST" name="R_homoserine_O_succinyltransferase" reversible="false">
10499 <notes>
10500 <html:p>GENE_ASSOCIATION: b4013</html:p>
10501 <html:p>PROTEIN_ASSOCIATION: MetA</html:p>
10502 <html:p>SUBSYSTEM: S_Methionine_Metabolism</html:p>
10503 <html:p>PROTEIN_CLASS: 2.3.1.46</html:p>
10504 </notes>
10505 <listOfReactants>
10506 <speciesReference species="M_hom_L_c" stoichiometry="1.000000"/>
10507 <speciesReference species="M_succoa_c" stoichiometry="1.000000"/>
10508 </listOfReactants>
10509 <listOfProducts>
10510 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
10511 <speciesReference species="M_suchms_c" stoichiometry="1.000000"/>
10512 </listOfProducts>
10513 </reaction>
10514 <reaction id="R_HSTPT" name="R_histidinol_phosphate_transaminase" reversible="false">
10515 <notes>
10516 <html:p>GENE_ASSOCIATION: b2021</html:p>
10517 <html:p>PROTEIN_ASSOCIATION: HisC</html:p>
10518 <html:p>SUBSYSTEM: S_Histidine_Metabolism</html:p>
10519 <html:p>PROTEIN_CLASS: 2.6.1.9</html:p>
10520 </notes>
10521 <listOfReactants>
10522 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
10523 <speciesReference species="M_imacp_c" stoichiometry="1.000000"/>
10524 </listOfReactants>
10525 <listOfProducts>
10526 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
10527 <speciesReference species="M_hisp_c" stoichiometry="1.000000"/>
10528 </listOfProducts>
10529 </reaction>
10530 <reaction id="R_HXPRT" name="R_hypoxanthine_phosphoribosyltransferase__Hypoxanthine_" reversible="false">
10531 <notes>
10532 <html:p>GENE_ASSOCIATION: ( b0238 or b0125 )</html:p>
10533 <html:p>PROTEIN_ASSOCIATION: ( Gpt ) or ( Hpt )</html:p>
10534 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
10535 <html:p>PROTEIN_CLASS: 2.4.2.8</html:p>
10536 </notes>
10537 <listOfReactants>
10538 <speciesReference species="M_hxan_c" stoichiometry="1.000000"/>
10539 <speciesReference species="M_prpp_c" stoichiometry="1.000000"/>
10540 </listOfReactants>
10541 <listOfProducts>
10542 <speciesReference species="M_imp_c" stoichiometry="1.000000"/>
10543 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
10544 </listOfProducts>
10545 </reaction>
10546 <reaction id="R_HYD1" name="R_hydrogenase__ubiquinone_8_2_protons_" reversible="false">
10547 <notes>
10548 <html:p>GENE_ASSOCIATION: ( ( b0972 and b0973 and b0974 ) or ( b2994 and b2997 ) or ( b2719 and b2720 and b2721 and b2722 and b2723 and b2724 ) )</html:p>
10549 <html:p>PROTEIN_ASSOCIATION: ( HyaA ) or ( HybC ) or ( HycB )</html:p>
10550 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
10551 <html:p>PROTEIN_CLASS: 1.18.99.1</html:p>
10552 </notes>
10553 <listOfReactants>
10554 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
10555 <speciesReference species="M_h2_c" stoichiometry="1.000000"/>
10556 <speciesReference species="M_q8_c" stoichiometry="1.000000"/>
10557 </listOfReactants>
10558 <listOfProducts>
10559 <speciesReference species="M_q8h2_c" stoichiometry="1.000000"/>
10560 <speciesReference species="M_h_e" stoichiometry="2.000000"/>
10561 </listOfProducts>
10562 </reaction>
10563 <reaction id="R_HYD2" name="R_Hydrogenase__menaquinone8_2_protons_" reversible="false">
10564 <notes>
10565 <html:p>GENE_ASSOCIATION: ( ( b2994 and b2997 ) or ( b0972 and b0973 and b0974 ) )</html:p>
10566 <html:p>PROTEIN_ASSOCIATION: ( HybC ) or ( HyaA )</html:p>
10567 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
10568 <html:p>PROTEIN_CLASS: 1.18.99.1</html:p>
10569 </notes>
10570 <listOfReactants>
10571 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
10572 <speciesReference species="M_h2_c" stoichiometry="1.000000"/>
10573 <speciesReference species="M_mqn8_c" stoichiometry="1.000000"/>
10574 </listOfReactants>
10575 <listOfProducts>
10576 <speciesReference species="M_mql8_c" stoichiometry="1.000000"/>
10577 <speciesReference species="M_h_e" stoichiometry="2.000000"/>
10578 </listOfProducts>
10579 </reaction>
10580 <reaction id="R_HYD3" name="R_Hydrogenase__Demethylmenaquinone_8_2_protons_" reversible="false">
10581 <notes>
10582 <html:p>GENE_ASSOCIATION: ( ( b0972 and b0973 and b0974 ) or ( b2994 and b2997 ) )</html:p>
10583 <html:p>PROTEIN_ASSOCIATION: ( HyaA ) or ( HybC )</html:p>
10584 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
10585 <html:p>PROTEIN_CLASS: 1.18.99.1</html:p>
10586 </notes>
10587 <listOfReactants>
10588 <speciesReference species="M_2dmmq8_c" stoichiometry="1.000000"/>
10589 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
10590 <speciesReference species="M_h2_c" stoichiometry="1.000000"/>
10591 </listOfReactants>
10592 <listOfProducts>
10593 <speciesReference species="M_2dmmql8_c" stoichiometry="1.000000"/>
10594 <speciesReference species="M_h_e" stoichiometry="2.000000"/>
10595 </listOfProducts>
10596 </reaction>
10597 <reaction id="R_HYPOE" name="R_hypothetical_enyme" reversible="false">
10598 <notes>
10599 <html:p>GENE_ASSOCIATION: </html:p>
10600 <html:p>PROTEIN_ASSOCIATION: </html:p>
10601 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
10602 <html:p>PROTEIN_CLASS: </html:p>
10603 </notes>
10604 <listOfReactants>
10605 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
10606 <speciesReference species="M_pyam5p_c" stoichiometry="1.000000"/>
10607 </listOfReactants>
10608 <listOfProducts>
10609 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
10610 <speciesReference species="M_pydam_c" stoichiometry="1.000000"/>
10611 </listOfProducts>
10612 </reaction>
10613 <reaction id="R_HYXNt" name="R_Hypoxanthine_transport" reversible="true">
10614 <notes>
10615 <html:p>GENE_ASSOCIATION: </html:p>
10616 <html:p>PROTEIN_ASSOCIATION: </html:p>
10617 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
10618 <html:p>PROTEIN_CLASS: </html:p>
10619 </notes>
10620 <listOfReactants>
10621 <speciesReference species="M_hxan_e" stoichiometry="1.000000"/>
10622 </listOfReactants>
10623 <listOfProducts>
10624 <speciesReference species="M_hxan_c" stoichiometry="1.000000"/>
10625 </listOfProducts>
10626 </reaction>
10627 <reaction id="R_ICDHyr" name="R_isocitrate_dehydrogenase__NADP_" reversible="true">
10628 <notes>
10629 <html:p>GENE_ASSOCIATION: b1136</html:p>
10630 <html:p>PROTEIN_ASSOCIATION: Icd</html:p>
10631 <html:p>SUBSYSTEM: S_Citric_Acid_Cycle</html:p>
10632 <html:p>PROTEIN_CLASS: 1.1.1.42</html:p>
10633 </notes>
10634 <listOfReactants>
10635 <speciesReference species="M_icit_c" stoichiometry="1.000000"/>
10636 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
10637 </listOfReactants>
10638 <listOfProducts>
10639 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
10640 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
10641 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
10642 </listOfProducts>
10643 </reaction>
10644 <reaction id="R_ICHORSi" name="R_Isochorismate_Synthase" reversible="false">
10645 <notes>
10646 <html:p>GENE_ASSOCIATION: ( b2265 or b0593 )</html:p>
10647 <html:p>PROTEIN_ASSOCIATION: ( MenF ) or ( EntC )</html:p>
10648 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
10649 <html:p>PROTEIN_CLASS: </html:p>
10650 </notes>
10651 <listOfReactants>
10652 <speciesReference species="M_chor_c" stoichiometry="1.000000"/>
10653 </listOfReactants>
10654 <listOfProducts>
10655 <speciesReference species="M_ichor_c" stoichiometry="1.000000"/>
10656 </listOfProducts>
10657 </reaction>
10658 <reaction id="R_ICHORT" name="R_isochorismatase" reversible="false">
10659 <notes>
10660 <html:p>GENE_ASSOCIATION: b0595</html:p>
10661 <html:p>PROTEIN_ASSOCIATION: EntB</html:p>
10662 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
10663 <html:p>PROTEIN_CLASS: 3.3.2.1</html:p>
10664 </notes>
10665 <listOfReactants>
10666 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
10667 <speciesReference species="M_ichor_c" stoichiometry="1.000000"/>
10668 </listOfReactants>
10669 <listOfProducts>
10670 <speciesReference species="M_23ddhb_c" stoichiometry="1.000000"/>
10671 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
10672 </listOfProducts>
10673 </reaction>
10674 <reaction id="R_ICL" name="R_Isocitrate_lyase" reversible="false">
10675 <notes>
10676 <html:p>GENE_ASSOCIATION: b4015</html:p>
10677 <html:p>PROTEIN_ASSOCIATION: AceA</html:p>
10678 <html:p>SUBSYSTEM: S_Anaplerotic_reactions</html:p>
10679 <html:p>PROTEIN_CLASS: 4.1.3.1</html:p>
10680 </notes>
10681 <listOfReactants>
10682 <speciesReference species="M_icit_c" stoichiometry="1.000000"/>
10683 </listOfReactants>
10684 <listOfProducts>
10685 <speciesReference species="M_glx_c" stoichiometry="1.000000"/>
10686 <speciesReference species="M_succ_c" stoichiometry="1.000000"/>
10687 </listOfProducts>
10688 </reaction>
10689 <reaction id="R_IDOND" name="R_L_idonate_5_dehydrogenase" reversible="true">
10690 <notes>
10691 <html:p>GENE_ASSOCIATION: b4267</html:p>
10692 <html:p>PROTEIN_ASSOCIATION: IdnD</html:p>
10693 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
10694 <html:p>PROTEIN_CLASS: </html:p>
10695 </notes>
10696 <listOfReactants>
10697 <speciesReference species="M_5dglcn_c" stoichiometry="1.000000"/>
10698 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10699 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
10700 </listOfReactants>
10701 <listOfProducts>
10702 <speciesReference species="M_idon_L_c" stoichiometry="1.000000"/>
10703 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
10704 </listOfProducts>
10705 </reaction>
10706 <reaction id="R_IDOND2" name="R_L_indonate_5_dehydrogenase__NADP_" reversible="false">
10707 <notes>
10708 <html:p>GENE_ASSOCIATION: b4267</html:p>
10709 <html:p>PROTEIN_ASSOCIATION: IdnD</html:p>
10710 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
10711 <html:p>PROTEIN_CLASS: </html:p>
10712 </notes>
10713 <listOfReactants>
10714 <speciesReference species="M_5dglcn_c" stoichiometry="1.000000"/>
10715 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10716 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
10717 </listOfReactants>
10718 <listOfProducts>
10719 <speciesReference species="M_idon_L_c" stoichiometry="1.000000"/>
10720 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
10721 </listOfProducts>
10722 </reaction>
10723 <reaction id="R_IDONt2r" name="R_L_idonate_transport_via_proton_symport__reversible" reversible="true">
10724 <notes>
10725 <html:p>GENE_ASSOCIATION: b4265</html:p>
10726 <html:p>PROTEIN_ASSOCIATION: IdnT</html:p>
10727 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
10728 <html:p>PROTEIN_CLASS: </html:p>
10729 </notes>
10730 <listOfReactants>
10731 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
10732 <speciesReference species="M_idon_L_e" stoichiometry="1.000000"/>
10733 </listOfReactants>
10734 <listOfProducts>
10735 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10736 <speciesReference species="M_idon_L_c" stoichiometry="1.000000"/>
10737 </listOfProducts>
10738 </reaction>
10739 <reaction id="R_IG3PS" name="R_Imidazole_glycerol_3_phosphate_synthase" reversible="false">
10740 <notes>
10741 <html:p>GENE_ASSOCIATION: ( b2023 and b2025 )</html:p>
10742 <html:p>PROTEIN_ASSOCIATION: HisF</html:p>
10743 <html:p>SUBSYSTEM: S_Histidine_Metabolism</html:p>
10744 <html:p>PROTEIN_CLASS: </html:p>
10745 </notes>
10746 <listOfReactants>
10747 <speciesReference species="M_gln_L_c" stoichiometry="1.000000"/>
10748 <speciesReference species="M_prlp_c" stoichiometry="1.000000"/>
10749 </listOfReactants>
10750 <listOfProducts>
10751 <speciesReference species="M_aicar_c" stoichiometry="1.000000"/>
10752 <speciesReference species="M_eig3p_c" stoichiometry="1.000000"/>
10753 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
10754 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10755 </listOfProducts>
10756 </reaction>
10757 <reaction id="R_IGPDH" name="R_imidazoleglycerol_phosphate_dehydratase" reversible="false">
10758 <notes>
10759 <html:p>GENE_ASSOCIATION: b2022</html:p>
10760 <html:p>PROTEIN_ASSOCIATION: HisB</html:p>
10761 <html:p>SUBSYSTEM: S_Histidine_Metabolism</html:p>
10762 <html:p>PROTEIN_CLASS: 4.2.1.19</html:p>
10763 </notes>
10764 <listOfReactants>
10765 <speciesReference species="M_eig3p_c" stoichiometry="1.000000"/>
10766 </listOfReactants>
10767 <listOfProducts>
10768 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
10769 <speciesReference species="M_imacp_c" stoichiometry="1.000000"/>
10770 </listOfProducts>
10771 </reaction>
10772 <reaction id="R_IGPS" name="R_indole_3_glycerol_phosphate_synthase" reversible="false">
10773 <notes>
10774 <html:p>GENE_ASSOCIATION: b1262</html:p>
10775 <html:p>PROTEIN_ASSOCIATION: TrpCec</html:p>
10776 <html:p>SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism</html:p>
10777 <html:p>PROTEIN_CLASS: 4.1.1.48</html:p>
10778 </notes>
10779 <listOfReactants>
10780 <speciesReference species="M_2cpr5p_c" stoichiometry="1.000000"/>
10781 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10782 </listOfReactants>
10783 <listOfProducts>
10784 <speciesReference species="M_3ig3p_c" stoichiometry="1.000000"/>
10785 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
10786 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
10787 </listOfProducts>
10788 </reaction>
10789 <reaction id="R_ILETA" name="R_isoleucine_transaminase" reversible="true">
10790 <notes>
10791 <html:p>GENE_ASSOCIATION: b3770</html:p>
10792 <html:p>PROTEIN_ASSOCIATION: IlvE</html:p>
10793 <html:p>SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism</html:p>
10794 <html:p>PROTEIN_CLASS: 2.6.1.42</html:p>
10795 </notes>
10796 <listOfReactants>
10797 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
10798 <speciesReference species="M_ile_L_c" stoichiometry="1.000000"/>
10799 </listOfReactants>
10800 <listOfProducts>
10801 <speciesReference species="M_3mop_c" stoichiometry="1.000000"/>
10802 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
10803 </listOfProducts>
10804 </reaction>
10805 <reaction id="R_ILEabc" name="R_L_isoleucine_transport_via_ABC_system" reversible="false">
10806 <notes>
10807 <html:p>GENE_ASSOCIATION: ( b3454 and b3455 and b3457 and b3460 and b3456 )</html:p>
10808 <html:p>PROTEIN_ASSOCIATION: ( LivF and LivG and LivH and LivJ and LivM )</html:p>
10809 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
10810 <html:p>PROTEIN_CLASS: </html:p>
10811 </notes>
10812 <listOfReactants>
10813 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
10814 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
10815 <speciesReference species="M_ile_L_e" stoichiometry="1.000000"/>
10816 </listOfReactants>
10817 <listOfProducts>
10818 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
10819 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10820 <speciesReference species="M_ile_L_c" stoichiometry="1.000000"/>
10821 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
10822 </listOfProducts>
10823 </reaction>
10824 <reaction id="R_ILEt2r" name="R_L_isoleucine_reversible_transport_via_proton_symport" reversible="true">
10825 <notes>
10826 <html:p>GENE_ASSOCIATION: b0401</html:p>
10827 <html:p>PROTEIN_ASSOCIATION: BrnQ</html:p>
10828 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
10829 <html:p>PROTEIN_CLASS: </html:p>
10830 </notes>
10831 <listOfReactants>
10832 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
10833 <speciesReference species="M_ile_L_e" stoichiometry="1.000000"/>
10834 </listOfReactants>
10835 <listOfProducts>
10836 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10837 <speciesReference species="M_ile_L_c" stoichiometry="1.000000"/>
10838 </listOfProducts>
10839 </reaction>
10840 <reaction id="R_IMPC" name="R_IMP_cyclohydrolase" reversible="true">
10841 <notes>
10842 <html:p>GENE_ASSOCIATION: b4006</html:p>
10843 <html:p>PROTEIN_ASSOCIATION: PurH</html:p>
10844 <html:p>SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis</html:p>
10845 <html:p>PROTEIN_CLASS: 3.5.4.10</html:p>
10846 </notes>
10847 <listOfReactants>
10848 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
10849 <speciesReference species="M_imp_c" stoichiometry="1.000000"/>
10850 </listOfReactants>
10851 <listOfProducts>
10852 <speciesReference species="M_fprica_c" stoichiometry="1.000000"/>
10853 </listOfProducts>
10854 </reaction>
10855 <reaction id="R_IMPD" name="R_IMP_dehydrogenase" reversible="false">
10856 <notes>
10857 <html:p>GENE_ASSOCIATION: b2508</html:p>
10858 <html:p>PROTEIN_ASSOCIATION: GuaB</html:p>
10859 <html:p>SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis</html:p>
10860 <html:p>PROTEIN_CLASS: 1.1.1.205</html:p>
10861 </notes>
10862 <listOfReactants>
10863 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
10864 <speciesReference species="M_imp_c" stoichiometry="1.000000"/>
10865 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
10866 </listOfReactants>
10867 <listOfProducts>
10868 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10869 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
10870 <speciesReference species="M_xmp_c" stoichiometry="1.000000"/>
10871 </listOfProducts>
10872 </reaction>
10873 <reaction id="R_INDOLEt2r" name="R_Indole_transport_via_proton_symport__reversible" reversible="true">
10874 <notes>
10875 <html:p>GENE_ASSOCIATION: b3161</html:p>
10876 <html:p>PROTEIN_ASSOCIATION: Mtr</html:p>
10877 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
10878 <html:p>PROTEIN_CLASS: </html:p>
10879 </notes>
10880 <listOfReactants>
10881 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
10882 <speciesReference species="M_indole_e" stoichiometry="1.000000"/>
10883 </listOfReactants>
10884 <listOfProducts>
10885 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10886 <speciesReference species="M_indole_c" stoichiometry="1.000000"/>
10887 </listOfProducts>
10888 </reaction>
10889 <reaction id="R_INSK" name="R_insosine_kinase" reversible="false">
10890 <notes>
10891 <html:p>GENE_ASSOCIATION: b0477</html:p>
10892 <html:p>PROTEIN_ASSOCIATION: Gsk</html:p>
10893 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
10894 <html:p>PROTEIN_CLASS: 2.7.1.73</html:p>
10895 </notes>
10896 <listOfReactants>
10897 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
10898 <speciesReference species="M_ins_c" stoichiometry="1.000000"/>
10899 </listOfReactants>
10900 <listOfProducts>
10901 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
10902 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10903 <speciesReference species="M_imp_c" stoichiometry="1.000000"/>
10904 </listOfProducts>
10905 </reaction>
10906 <reaction id="R_INSt2" name="R_inosine_transport_in_via_proton_symport" reversible="false">
10907 <notes>
10908 <html:p>GENE_ASSOCIATION: b2964</html:p>
10909 <html:p>PROTEIN_ASSOCIATION: NupG</html:p>
10910 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
10911 <html:p>PROTEIN_CLASS: </html:p>
10912 </notes>
10913 <listOfReactants>
10914 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
10915 <speciesReference species="M_ins_e" stoichiometry="1.000000"/>
10916 </listOfReactants>
10917 <listOfProducts>
10918 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10919 <speciesReference species="M_ins_c" stoichiometry="1.000000"/>
10920 </listOfProducts>
10921 </reaction>
10922 <reaction id="R_INSt2r" name="R_inosine_transport_in_via_proton_symport__reversible" reversible="true">
10923 <notes>
10924 <html:p>GENE_ASSOCIATION: b2406</html:p>
10925 <html:p>PROTEIN_ASSOCIATION: XapB</html:p>
10926 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
10927 <html:p>PROTEIN_CLASS: </html:p>
10928 </notes>
10929 <listOfReactants>
10930 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
10931 <speciesReference species="M_ins_e" stoichiometry="1.000000"/>
10932 </listOfReactants>
10933 <listOfProducts>
10934 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10935 <speciesReference species="M_ins_c" stoichiometry="1.000000"/>
10936 </listOfProducts>
10937 </reaction>
10938 <reaction id="R_IPDDIi" name="R_isopentenyl_diphosphate_D_isomerase" reversible="false">
10939 <notes>
10940 <html:p>GENE_ASSOCIATION: b2889</html:p>
10941 <html:p>PROTEIN_ASSOCIATION: Idi</html:p>
10942 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
10943 <html:p>PROTEIN_CLASS: 5.3.3.2</html:p>
10944 </notes>
10945 <listOfReactants>
10946 <speciesReference species="M_ipdp_c" stoichiometry="1.000000"/>
10947 </listOfReactants>
10948 <listOfProducts>
10949 <speciesReference species="M_dmpp_c" stoichiometry="1.000000"/>
10950 </listOfProducts>
10951 </reaction>
10952 <reaction id="R_IPDPS" name="R_1_hydroxy_2_methyl_2__E__butenyl_4_diphosphate_reductase__ipdp_" reversible="false">
10953 <notes>
10954 <html:p>GENE_ASSOCIATION: b0029</html:p>
10955 <html:p>PROTEIN_ASSOCIATION: LytB</html:p>
10956 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
10957 <html:p>PROTEIN_CLASS: </html:p>
10958 </notes>
10959 <listOfReactants>
10960 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10961 <speciesReference species="M_h2mb4p_c" stoichiometry="1.000000"/>
10962 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
10963 </listOfReactants>
10964 <listOfProducts>
10965 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
10966 <speciesReference species="M_ipdp_c" stoichiometry="1.000000"/>
10967 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
10968 </listOfProducts>
10969 </reaction>
10970 <reaction id="R_IPMD" name="R_3_isopropylmalate_dehydrogenase" reversible="false">
10971 <notes>
10972 <html:p>GENE_ASSOCIATION: b0073</html:p>
10973 <html:p>PROTEIN_ASSOCIATION: LeuB</html:p>
10974 <html:p>SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism</html:p>
10975 <html:p>PROTEIN_CLASS: 1.1.1.85</html:p>
10976 </notes>
10977 <listOfReactants>
10978 <speciesReference species="M_3c2hmp_c" stoichiometry="1.000000"/>
10979 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
10980 </listOfReactants>
10981 <listOfProducts>
10982 <speciesReference species="M_3c4mop_c" stoichiometry="1.000000"/>
10983 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
10984 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
10985 </listOfProducts>
10986 </reaction>
10987 <reaction id="R_IPPMIa" name="R_3_isopropylmalate_dehydratase" reversible="true">
10988 <notes>
10989 <html:p>GENE_ASSOCIATION: ( b0071 and b0072 )</html:p>
10990 <html:p>PROTEIN_ASSOCIATION: LeuC</html:p>
10991 <html:p>SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism</html:p>
10992 <html:p>PROTEIN_CLASS: 4.2.1.33</html:p>
10993 </notes>
10994 <listOfReactants>
10995 <speciesReference species="M_3c2hmp_c" stoichiometry="1.000000"/>
10996 </listOfReactants>
10997 <listOfProducts>
10998 <speciesReference species="M_2ippm_c" stoichiometry="1.000000"/>
10999 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
11000 </listOfProducts>
11001 </reaction>
11002 <reaction id="R_IPPMIb" name="R_2_isopropylmalate_hydratase" reversible="true">
11003 <notes>
11004 <html:p>GENE_ASSOCIATION: ( b0071 and b0072 )</html:p>
11005 <html:p>PROTEIN_ASSOCIATION: LeuC</html:p>
11006 <html:p>SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism</html:p>
11007 <html:p>PROTEIN_CLASS: 4.2.1.33</html:p>
11008 </notes>
11009 <listOfReactants>
11010 <speciesReference species="M_2ippm_c" stoichiometry="1.000000"/>
11011 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
11012 </listOfReactants>
11013 <listOfProducts>
11014 <speciesReference species="M_3c3hmp_c" stoichiometry="1.000000"/>
11015 </listOfProducts>
11016 </reaction>
11017 <reaction id="R_IPPS" name="R_2_isopropylmalate_synthase" reversible="false">
11018 <notes>
11019 <html:p>GENE_ASSOCIATION: b0074</html:p>
11020 <html:p>PROTEIN_ASSOCIATION: LeuA</html:p>
11021 <html:p>SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism</html:p>
11022 <html:p>PROTEIN_CLASS: 4.1.3.12</html:p>
11023 </notes>
11024 <listOfReactants>
11025 <speciesReference species="M_3mob_c" stoichiometry="1.000000"/>
11026 <speciesReference species="M_accoa_c" stoichiometry="1.000000"/>
11027 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
11028 </listOfReactants>
11029 <listOfProducts>
11030 <speciesReference species="M_3c3hmp_c" stoichiometry="1.000000"/>
11031 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
11032 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11033 </listOfProducts>
11034 </reaction>
11035 <reaction id="R_KARA1i" name="R_acetohydroxy_acid_isomeroreductase" reversible="false">
11036 <notes>
11037 <html:p>GENE_ASSOCIATION: b3774</html:p>
11038 <html:p>PROTEIN_ASSOCIATION: IlvCec</html:p>
11039 <html:p>SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism</html:p>
11040 <html:p>PROTEIN_CLASS: 1.1.1.86</html:p>
11041 </notes>
11042 <listOfReactants>
11043 <speciesReference species="M_alac_S_c" stoichiometry="1.000000"/>
11044 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11045 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
11046 </listOfReactants>
11047 <listOfProducts>
11048 <speciesReference species="M_23dhmb_c" stoichiometry="1.000000"/>
11049 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
11050 </listOfProducts>
11051 </reaction>
11052 <reaction id="R_KARA2i" name="R_ketol_acid_reductoisomerase__2_Aceto_2_hydroxybutanoate_" reversible="false">
11053 <notes>
11054 <html:p>GENE_ASSOCIATION: b3774</html:p>
11055 <html:p>PROTEIN_ASSOCIATION: IlvCec</html:p>
11056 <html:p>SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism</html:p>
11057 <html:p>PROTEIN_CLASS: 1.1.1.86</html:p>
11058 </notes>
11059 <listOfReactants>
11060 <speciesReference species="M_2ahbut_c" stoichiometry="1.000000"/>
11061 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11062 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
11063 </listOfReactants>
11064 <listOfProducts>
11065 <speciesReference species="M_23dhmp_c" stoichiometry="1.000000"/>
11066 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
11067 </listOfProducts>
11068 </reaction>
11069 <reaction id="R_KAS14" name="R_beta_ketoacyl_ACP_synthase" reversible="false">
11070 <notes>
11071 <html:p>GENE_ASSOCIATION: ( b2323 or b1095 )</html:p>
11072 <html:p>PROTEIN_ASSOCIATION: ( FabB ) or ( FabF )</html:p>
11073 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
11074 <html:p>PROTEIN_CLASS: 2.3.1.41</html:p>
11075 </notes>
11076 <listOfReactants>
11077 <speciesReference species="M_acACP_c" stoichiometry="1.000000"/>
11078 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11079 <speciesReference species="M_malACP_c" stoichiometry="1.000000"/>
11080 </listOfReactants>
11081 <listOfProducts>
11082 <speciesReference species="M_ACP_c" stoichiometry="1.000000"/>
11083 <speciesReference species="M_actACP_c" stoichiometry="1.000000"/>
11084 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
11085 </listOfProducts>
11086 </reaction>
11087 <reaction id="R_KAS15" name="R_beta_ketoacyl_ACP_synthase__2_" reversible="false">
11088 <notes>
11089 <html:p>GENE_ASSOCIATION: b1091</html:p>
11090 <html:p>PROTEIN_ASSOCIATION: FabHec</html:p>
11091 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
11092 <html:p>PROTEIN_CLASS: </html:p>
11093 </notes>
11094 <listOfReactants>
11095 <speciesReference species="M_accoa_c" stoichiometry="1.000000"/>
11096 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11097 <speciesReference species="M_malACP_c" stoichiometry="1.000000"/>
11098 </listOfReactants>
11099 <listOfProducts>
11100 <speciesReference species="M_actACP_c" stoichiometry="1.000000"/>
11101 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
11102 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
11103 </listOfProducts>
11104 </reaction>
11105 <reaction id="R_KAS16" name="R_3_hydroxy_myristoyl_ACP_synthesis" reversible="false">
11106 <notes>
11107 <html:p>GENE_ASSOCIATION: ( ( b2323 and b1093 ) or ( b1095 and b1093 ) )</html:p>
11108 <html:p>PROTEIN_ASSOCIATION: ( FabB and FabGec ) or ( FabF and FabGec )</html:p>
11109 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
11110 <html:p>PROTEIN_CLASS: </html:p>
11111 </notes>
11112 <listOfReactants>
11113 <speciesReference species="M_ddcaACP_c" stoichiometry="1.000000"/>
11114 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
11115 <speciesReference species="M_malACP_c" stoichiometry="1.000000"/>
11116 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
11117 </listOfReactants>
11118 <listOfProducts>
11119 <speciesReference species="M_3hmrsACP_c" stoichiometry="1.000000"/>
11120 <speciesReference species="M_ACP_c" stoichiometry="1.000000"/>
11121 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
11122 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
11123 </listOfProducts>
11124 </reaction>
11125 <reaction id="R_KDOCT2" name="R_3_deoxy_manno_octulosonate_cytidylyltransferase" reversible="false">
11126 <notes>
11127 <html:p>GENE_ASSOCIATION: b0918</html:p>
11128 <html:p>PROTEIN_ASSOCIATION: KdsBec</html:p>
11129 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
11130 <html:p>PROTEIN_CLASS: 2.7.7.38</html:p>
11131 </notes>
11132 <listOfReactants>
11133 <speciesReference species="M_ctp_c" stoichiometry="1.000000"/>
11134 <speciesReference species="M_kdo_c" stoichiometry="1.000000"/>
11135 </listOfReactants>
11136 <listOfProducts>
11137 <speciesReference species="M_ckdo_c" stoichiometry="1.000000"/>
11138 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
11139 </listOfProducts>
11140 </reaction>
11141 <reaction id="R_KDOPP" name="R_3_deoxy_manno_octulosonate_8_phosphatase" reversible="false">
11142 <notes>
11143 <html:p>GENE_ASSOCIATION: </html:p>
11144 <html:p>PROTEIN_ASSOCIATION: </html:p>
11145 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
11146 <html:p>PROTEIN_CLASS: 3.1.3.45</html:p>
11147 </notes>
11148 <listOfReactants>
11149 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
11150 <speciesReference species="M_kdo8p_c" stoichiometry="1.000000"/>
11151 </listOfReactants>
11152 <listOfProducts>
11153 <speciesReference species="M_kdo_c" stoichiometry="1.000000"/>
11154 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
11155 </listOfProducts>
11156 </reaction>
11157 <reaction id="R_KDOPS" name="R_3_deoxy__D_manno_octulosonic__acid_8_phosphate_synthase" reversible="false">
11158 <notes>
11159 <html:p>GENE_ASSOCIATION: b1215</html:p>
11160 <html:p>PROTEIN_ASSOCIATION: KdsA</html:p>
11161 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
11162 <html:p>PROTEIN_CLASS: 4.1.2.16</html:p>
11163 </notes>
11164 <listOfReactants>
11165 <speciesReference species="M_ara5p_c" stoichiometry="1.000000"/>
11166 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
11167 <speciesReference species="M_pep_c" stoichiometry="1.000000"/>
11168 </listOfReactants>
11169 <listOfProducts>
11170 <speciesReference species="M_kdo8p_c" stoichiometry="1.000000"/>
11171 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
11172 </listOfProducts>
11173 </reaction>
11174 <reaction id="R_KG6PDC" name="R_3_keto_L_gulonate_6_phosphate_decarboxylase" reversible="false">
11175 <notes>
11176 <html:p>GENE_ASSOCIATION: ( b4196 or b3581 )</html:p>
11177 <html:p>PROTEIN_ASSOCIATION: ( SgaH ) or ( SgbH )</html:p>
11178 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
11179 <html:p>PROTEIN_CLASS: </html:p>
11180 </notes>
11181 <listOfReactants>
11182 <speciesReference species="M_3dhgulnp_c" stoichiometry="1.000000"/>
11183 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11184 </listOfReactants>
11185 <listOfProducts>
11186 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
11187 <speciesReference species="M_xu5p_L_c" stoichiometry="1.000000"/>
11188 </listOfProducts>
11189 </reaction>
11190 <reaction id="R_Kabc" name="R_Potassium_ABC_transporter" reversible="false">
11191 <notes>
11192 <html:p>GENE_ASSOCIATION: ( b0696 and b0697 and b0698 )</html:p>
11193 <html:p>PROTEIN_ASSOCIATION: KdpABC</html:p>
11194 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
11195 <html:p>PROTEIN_CLASS: </html:p>
11196 </notes>
11197 <listOfReactants>
11198 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
11199 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
11200 <speciesReference species="M_k_e" stoichiometry="1.000000"/>
11201 </listOfReactants>
11202 <listOfProducts>
11203 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
11204 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11205 <speciesReference species="M_k_c" stoichiometry="1.000000"/>
11206 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
11207 </listOfProducts>
11208 </reaction>
11209 <reaction id="R_Kt2r" name="R_potassium_reversible_transport__via_proton_symport" reversible="true">
11210 <notes>
11211 <html:p>GENE_ASSOCIATION: ( b1363 or b3849 )</html:p>
11212 <html:p>PROTEIN_ASSOCIATION: ( TrkG ) or ( TrkH )</html:p>
11213 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
11214 <html:p>PROTEIN_CLASS: </html:p>
11215 </notes>
11216 <listOfReactants>
11217 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
11218 <speciesReference species="M_k_e" stoichiometry="1.000000"/>
11219 </listOfReactants>
11220 <listOfProducts>
11221 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11222 <speciesReference species="M_k_c" stoichiometry="1.000000"/>
11223 </listOfProducts>
11224 </reaction>
11225 <reaction id="R_LACZ" name="R_b_galactosidase" reversible="false">
11226 <notes>
11227 <html:p>GENE_ASSOCIATION: ( b0344 or b2132 )</html:p>
11228 <html:p>PROTEIN_ASSOCIATION: ( LacZ ) or ( BglX )</html:p>
11229 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
11230 <html:p>PROTEIN_CLASS: 3.2.1.23</html:p>
11231 </notes>
11232 <listOfReactants>
11233 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
11234 <speciesReference species="M_lcts_c" stoichiometry="1.000000"/>
11235 </listOfReactants>
11236 <listOfProducts>
11237 <speciesReference species="M_gal_c" stoichiometry="1.000000"/>
11238 <speciesReference species="M_glc_D_c" stoichiometry="1.000000"/>
11239 </listOfProducts>
11240 </reaction>
11241 <reaction id="R_LCAD" name="R_lactaldehyde_dehydrogenase" reversible="true">
11242 <notes>
11243 <html:p>GENE_ASSOCIATION: ( b1415 or b3588 or b0356 or b1300 )</html:p>
11244 <html:p>PROTEIN_ASSOCIATION: ( AldA ) or ( AldB ) or ( AdhC ) or ( AldH )</html:p>
11245 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
11246 <html:p>PROTEIN_CLASS: 1.2.1.21</html:p>
11247 </notes>
11248 <listOfReactants>
11249 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
11250 <speciesReference species="M_lald_L_c" stoichiometry="1.000000"/>
11251 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
11252 </listOfReactants>
11253 <listOfProducts>
11254 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
11255 <speciesReference species="M_lac_L_c" stoichiometry="1.000000"/>
11256 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
11257 </listOfProducts>
11258 </reaction>
11259 <reaction id="R_LCADi" name="R_lactaldehyde_dehydrogenase" reversible="false">
11260 <notes>
11261 <html:p>GENE_ASSOCIATION: b1241</html:p>
11262 <html:p>PROTEIN_ASSOCIATION: AdhE</html:p>
11263 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
11264 <html:p>PROTEIN_CLASS: 1.2.1.21</html:p>
11265 </notes>
11266 <listOfReactants>
11267 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
11268 <speciesReference species="M_lald_L_c" stoichiometry="1.000000"/>
11269 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
11270 </listOfReactants>
11271 <listOfProducts>
11272 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
11273 <speciesReference species="M_lac_L_c" stoichiometry="1.000000"/>
11274 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
11275 </listOfProducts>
11276 </reaction>
11277 <reaction id="R_LCARS" name="R_lacaldehyde_reductase__S_propane_1_2_diol_forming_" reversible="true">
11278 <notes>
11279 <html:p>GENE_ASSOCIATION: b2799</html:p>
11280 <html:p>PROTEIN_ASSOCIATION: FucO</html:p>
11281 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
11282 <html:p>PROTEIN_CLASS: 1.1.1.77</html:p>
11283 </notes>
11284 <listOfReactants>
11285 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11286 <speciesReference species="M_lald_L_c" stoichiometry="1.000000"/>
11287 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
11288 </listOfReactants>
11289 <listOfProducts>
11290 <speciesReference species="M_12ppd_S_c" stoichiometry="1.000000"/>
11291 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
11292 </listOfProducts>
11293 </reaction>
11294 <reaction id="R_LCTSt" name="R_Lactose_transport_via_proton_symport" reversible="true">
11295 <notes>
11296 <html:p>GENE_ASSOCIATION: b0343</html:p>
11297 <html:p>PROTEIN_ASSOCIATION: LacY</html:p>
11298 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
11299 <html:p>PROTEIN_CLASS: </html:p>
11300 </notes>
11301 <listOfReactants>
11302 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
11303 <speciesReference species="M_lcts_e" stoichiometry="1.000000"/>
11304 </listOfReactants>
11305 <listOfProducts>
11306 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11307 <speciesReference species="M_lcts_c" stoichiometry="1.000000"/>
11308 </listOfProducts>
11309 </reaction>
11310 <reaction id="R_LDH_D" name="R_D_lactate_dehydrogenase" reversible="true">
11311 <notes>
11312 <html:p>GENE_ASSOCIATION: ( b2133 or b1380 )</html:p>
11313 <html:p>PROTEIN_ASSOCIATION: ( Dld ) or ( Ldh )</html:p>
11314 <html:p>SUBSYSTEM: S_Pyruvate_Metabolism</html:p>
11315 <html:p>PROTEIN_CLASS: 1.1.1.28</html:p>
11316 </notes>
11317 <listOfReactants>
11318 <speciesReference species="M_lac_D_c" stoichiometry="1.000000"/>
11319 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
11320 </listOfReactants>
11321 <listOfProducts>
11322 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11323 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
11324 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
11325 </listOfProducts>
11326 </reaction>
11327 <reaction id="R_LDH_D2" name="R_D_lactate_dehydrogenase" reversible="false">
11328 <notes>
11329 <html:p>GENE_ASSOCIATION: b2133</html:p>
11330 <html:p>PROTEIN_ASSOCIATION: Dld</html:p>
11331 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
11332 <html:p>PROTEIN_CLASS: 1.1.2.4</html:p>
11333 </notes>
11334 <listOfReactants>
11335 <speciesReference species="M_lac_D_c" stoichiometry="1.000000"/>
11336 <speciesReference species="M_q8_c" stoichiometry="1.000000"/>
11337 </listOfReactants>
11338 <listOfProducts>
11339 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
11340 <speciesReference species="M_q8h2_c" stoichiometry="1.000000"/>
11341 </listOfProducts>
11342 </reaction>
11343 <reaction id="R_LEUTAi" name="R_leucine_transaminase__irreversible_" reversible="false">
11344 <notes>
11345 <html:p>GENE_ASSOCIATION: ( b3770 or b4054 )</html:p>
11346 <html:p>PROTEIN_ASSOCIATION: ( IlvE ) or ( TyrB )</html:p>
11347 <html:p>SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism</html:p>
11348 <html:p>PROTEIN_CLASS: 2.6.1.42</html:p>
11349 </notes>
11350 <listOfReactants>
11351 <speciesReference species="M_4mop_c" stoichiometry="1.000000"/>
11352 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
11353 </listOfReactants>
11354 <listOfProducts>
11355 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
11356 <speciesReference species="M_leu_L_c" stoichiometry="1.000000"/>
11357 </listOfProducts>
11358 </reaction>
11359 <reaction id="R_LEUabc" name="R_L_leucine_transport_via_ABC_system" reversible="false">
11360 <notes>
11361 <html:p>GENE_ASSOCIATION: ( ( b3454 and b3455 and b3457 and b3460 and b3456 ) or ( b3454 and b3455 and b3457 and b3458 and b3456 ) )</html:p>
11362 <html:p>PROTEIN_ASSOCIATION: ( LivF and LivG and LivH and LivJ and LivM ) or ( LivF and LivG and LivH and LivK and LivM )</html:p>
11363 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
11364 <html:p>PROTEIN_CLASS: </html:p>
11365 </notes>
11366 <listOfReactants>
11367 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
11368 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
11369 <speciesReference species="M_leu_L_e" stoichiometry="1.000000"/>
11370 </listOfReactants>
11371 <listOfProducts>
11372 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
11373 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11374 <speciesReference species="M_leu_L_c" stoichiometry="1.000000"/>
11375 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
11376 </listOfProducts>
11377 </reaction>
11378 <reaction id="R_LEUt2r" name="R_L_leucine_reversible_transport_via_proton_symport" reversible="true">
11379 <notes>
11380 <html:p>GENE_ASSOCIATION: b0401</html:p>
11381 <html:p>PROTEIN_ASSOCIATION: BrnQ</html:p>
11382 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
11383 <html:p>PROTEIN_CLASS: </html:p>
11384 </notes>
11385 <listOfReactants>
11386 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
11387 <speciesReference species="M_leu_L_e" stoichiometry="1.000000"/>
11388 </listOfReactants>
11389 <listOfProducts>
11390 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11391 <speciesReference species="M_leu_L_c" stoichiometry="1.000000"/>
11392 </listOfProducts>
11393 </reaction>
11394 <reaction id="R_LGTHL" name="R_lactoylglutathione_lyase" reversible="false">
11395 <notes>
11396 <html:p>GENE_ASSOCIATION: b1651</html:p>
11397 <html:p>PROTEIN_ASSOCIATION: GloA</html:p>
11398 <html:p>SUBSYSTEM: S_Methylglyoxal_Metabolism</html:p>
11399 <html:p>PROTEIN_CLASS: 4.4.1.5</html:p>
11400 </notes>
11401 <listOfReactants>
11402 <speciesReference species="M_gthrd_c" stoichiometry="1.000000"/>
11403 <speciesReference species="M_mthgxl_c" stoichiometry="1.000000"/>
11404 </listOfReactants>
11405 <listOfProducts>
11406 <speciesReference species="M_lgt_S_c" stoichiometry="1.000000"/>
11407 </listOfProducts>
11408 </reaction>
11409 <reaction id="R_LPADSS" name="R_Lipid_A_disaccaride_synthase" reversible="false">
11410 <notes>
11411 <html:p>GENE_ASSOCIATION: b0182</html:p>
11412 <html:p>PROTEIN_ASSOCIATION: LpxB</html:p>
11413 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
11414 <html:p>PROTEIN_CLASS: 2.4.1.182</html:p>
11415 </notes>
11416 <listOfReactants>
11417 <speciesReference species="M_lipidX_c" stoichiometry="1.000000"/>
11418 <speciesReference species="M_u23ga_c" stoichiometry="1.000000"/>
11419 </listOfReactants>
11420 <listOfProducts>
11421 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11422 <speciesReference species="M_lipidAds_c" stoichiometry="1.000000"/>
11423 <speciesReference species="M_udp_c" stoichiometry="1.000000"/>
11424 </listOfProducts>
11425 </reaction>
11426 <reaction id="R_LPLIPA1" name="R_Lysophospholipase_L__acyl_glycerophosphoglycerol_" reversible="false">
11427 <notes>
11428 <html:p>GENE_ASSOCIATION: b3825</html:p>
11429 <html:p>PROTEIN_ASSOCIATION: PldB</html:p>
11430 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
11431 <html:p>PROTEIN_CLASS: </html:p>
11432 </notes>
11433 <listOfReactants>
11434 <speciesReference species="M_agpg_EC_c" stoichiometry="0.020000"/>
11435 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
11436 </listOfReactants>
11437 <listOfProducts>
11438 <speciesReference species="M_g3pg_c" stoichiometry="1.000000"/>
11439 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11440 <speciesReference species="M_hdca_c" stoichiometry="0.360000"/>
11441 <speciesReference species="M_hdcea_c" stoichiometry="0.070000"/>
11442 <speciesReference species="M_ocdcea_c" stoichiometry="0.500000"/>
11443 <speciesReference species="M_ttdca_c" stoichiometry="0.020000"/>
11444 <speciesReference species="M_ttdcea_c" stoichiometry="0.050000"/>
11445 </listOfProducts>
11446 </reaction>
11447 <reaction id="R_LPLIPA2" name="R_Lysophospholipase_L__acyl_glycerophosphoethanolamine_" reversible="false">
11448 <notes>
11449 <html:p>GENE_ASSOCIATION: b3825</html:p>
11450 <html:p>PROTEIN_ASSOCIATION: PldB</html:p>
11451 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
11452 <html:p>PROTEIN_CLASS: </html:p>
11453 </notes>
11454 <listOfReactants>
11455 <speciesReference species="M_agpe_EC_c" stoichiometry="0.020000"/>
11456 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
11457 </listOfReactants>
11458 <listOfProducts>
11459 <speciesReference species="M_g3pe_c" stoichiometry="1.000000"/>
11460 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11461 <speciesReference species="M_hdca_c" stoichiometry="0.360000"/>
11462 <speciesReference species="M_hdcea_c" stoichiometry="0.070000"/>
11463 <speciesReference species="M_ocdcea_c" stoichiometry="0.500000"/>
11464 <speciesReference species="M_ttdca_c" stoichiometry="0.020000"/>
11465 <speciesReference species="M_ttdcea_c" stoichiometry="0.050000"/>
11466 </listOfProducts>
11467 </reaction>
11468 <reaction id="R_LPLIPA3" name="R_Lysophospholipase_L__acyl_glycerophosphocholine_" reversible="false">
11469 <notes>
11470 <html:p>GENE_ASSOCIATION: b3825</html:p>
11471 <html:p>PROTEIN_ASSOCIATION: PldB</html:p>
11472 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
11473 <html:p>PROTEIN_CLASS: </html:p>
11474 </notes>
11475 <listOfReactants>
11476 <speciesReference species="M_agpc_EC_c" stoichiometry="0.020000"/>
11477 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
11478 </listOfReactants>
11479 <listOfProducts>
11480 <speciesReference species="M_g3pc_c" stoichiometry="1.000000"/>
11481 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11482 <speciesReference species="M_hdca_c" stoichiometry="0.360000"/>
11483 <speciesReference species="M_hdcea_c" stoichiometry="0.070000"/>
11484 <speciesReference species="M_ocdcea_c" stoichiometry="0.500000"/>
11485 <speciesReference species="M_ttdca_c" stoichiometry="0.020000"/>
11486 <speciesReference species="M_ttdcea_c" stoichiometry="0.050000"/>
11487 </listOfProducts>
11488 </reaction>
11489 <reaction id="R_LPLIPA4" name="R_Lysophospholipase_L__acyl_transfer_to_phosphatidylglycerol_" reversible="false">
11490 <notes>
11491 <html:p>GENE_ASSOCIATION: b3825</html:p>
11492 <html:p>PROTEIN_ASSOCIATION: PldB</html:p>
11493 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
11494 <html:p>PROTEIN_CLASS: </html:p>
11495 </notes>
11496 <listOfReactants>
11497 <speciesReference species="M_agpe_EC_c" stoichiometry="0.020000"/>
11498 <speciesReference species="M_pg_EC_c" stoichiometry="0.020000"/>
11499 </listOfReactants>
11500 <listOfProducts>
11501 <speciesReference species="M_apg_EC_c" stoichiometry="0.020000"/>
11502 <speciesReference species="M_g3pe_c" stoichiometry="1.000000"/>
11503 </listOfProducts>
11504 </reaction>
11505 <reaction id="R_LPLIPA5" name="R_Lysophospholipase_L__acyl_transfer_to_phosphatidylglycerol_" reversible="false">
11506 <notes>
11507 <html:p>GENE_ASSOCIATION: b3825</html:p>
11508 <html:p>PROTEIN_ASSOCIATION: PldB</html:p>
11509 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
11510 <html:p>PROTEIN_CLASS: </html:p>
11511 </notes>
11512 <listOfReactants>
11513 <speciesReference species="M_agpc_EC_c" stoichiometry="0.020000"/>
11514 <speciesReference species="M_pg_EC_c" stoichiometry="0.020000"/>
11515 </listOfReactants>
11516 <listOfProducts>
11517 <speciesReference species="M_apg_EC_c" stoichiometry="0.020000"/>
11518 <speciesReference species="M_g3pc_c" stoichiometry="1.000000"/>
11519 </listOfProducts>
11520 </reaction>
11521 <reaction id="R_LPLIPA6" name="R_Lysophospholipase_L__acyl_transfer_to_phosphatidylglycerol_" reversible="false">
11522 <notes>
11523 <html:p>GENE_ASSOCIATION: b3825</html:p>
11524 <html:p>PROTEIN_ASSOCIATION: PldB</html:p>
11525 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
11526 <html:p>PROTEIN_CLASS: </html:p>
11527 </notes>
11528 <listOfReactants>
11529 <speciesReference species="M_agpg_EC_c" stoichiometry="0.020000"/>
11530 <speciesReference species="M_pg_EC_c" stoichiometry="0.020000"/>
11531 </listOfReactants>
11532 <listOfProducts>
11533 <speciesReference species="M_apg_EC_c" stoichiometry="0.020000"/>
11534 <speciesReference species="M_g3pg_c" stoichiometry="1.000000"/>
11535 </listOfProducts>
11536 </reaction>
11537 <reaction id="R_LPSSYN_EC" name="R_Lipopolysaccharide_synthesis__Ecoli_" reversible="false">
11538 <notes>
11539 <html:p>GENE_ASSOCIATION: ( b3621 and b3620 and b3631 and b3627 and b3626 and b3622 )</html:p>
11540 <html:p>PROTEIN_ASSOCIATION: ( RfaC and RfaF and RfaG and RfaI and RfaJec and RfaL )</html:p>
11541 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
11542 <html:p>PROTEIN_CLASS: </html:p>
11543 </notes>
11544 <listOfReactants>
11545 <speciesReference species="M_adphep_LD_c" stoichiometry="3.000000"/>
11546 <speciesReference species="M_cdpea_c" stoichiometry="2.000000"/>
11547 <speciesReference species="M_ckdo_c" stoichiometry="3.000000"/>
11548 <speciesReference species="M_lipa_c" stoichiometry="1.000000"/>
11549 <speciesReference species="M_udpg_c" stoichiometry="2.000000"/>
11550 </listOfReactants>
11551 <listOfProducts>
11552 <speciesReference species="M_adp_c" stoichiometry="3.000000"/>
11553 <speciesReference species="M_cdp_c" stoichiometry="2.000000"/>
11554 <speciesReference species="M_cmp_c" stoichiometry="3.000000"/>
11555 <speciesReference species="M_h_c" stoichiometry="10.000000"/>
11556 <speciesReference species="M_lps_EC_c" stoichiometry="1.000000"/>
11557 <speciesReference species="M_udp_c" stoichiometry="2.000000"/>
11558 </listOfProducts>
11559 </reaction>
11560 <reaction id="R_LYSDC" name="R_lysine_decarboxylase" reversible="false">
11561 <notes>
11562 <html:p>GENE_ASSOCIATION: ( b0186 or b4131 )</html:p>
11563 <html:p>PROTEIN_ASSOCIATION: ( LdcC ) or ( CadA )</html:p>
11564 <html:p>SUBSYSTEM: S_Threonine_and_Lysine_Metabolism</html:p>
11565 <html:p>PROTEIN_CLASS: 4.1.1.18</html:p>
11566 </notes>
11567 <listOfReactants>
11568 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11569 <speciesReference species="M_lys_L_c" stoichiometry="1.000000"/>
11570 </listOfReactants>
11571 <listOfProducts>
11572 <speciesReference species="M_15dap_c" stoichiometry="1.000000"/>
11573 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
11574 </listOfProducts>
11575 </reaction>
11576 <reaction id="R_LYSabc" name="R_L_lysine_transport_via_ABC_system" reversible="false">
11577 <notes>
11578 <html:p>GENE_ASSOCIATION: ( b2310 and b2307 and b2306 and b2308 )</html:p>
11579 <html:p>PROTEIN_ASSOCIATION: ( ArgT and HisM and HisP and HisQ )</html:p>
11580 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
11581 <html:p>PROTEIN_CLASS: </html:p>
11582 </notes>
11583 <listOfReactants>
11584 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
11585 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
11586 <speciesReference species="M_lys_L_e" stoichiometry="1.000000"/>
11587 </listOfReactants>
11588 <listOfProducts>
11589 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
11590 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11591 <speciesReference species="M_lys_L_c" stoichiometry="1.000000"/>
11592 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
11593 </listOfProducts>
11594 </reaction>
11595 <reaction id="R_LYSt2r" name="R_L_lysine_reversible_transport_via_proton_symport" reversible="true">
11596 <notes>
11597 <html:p>GENE_ASSOCIATION: b2156</html:p>
11598 <html:p>PROTEIN_ASSOCIATION: LysP</html:p>
11599 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
11600 <html:p>PROTEIN_CLASS: </html:p>
11601 </notes>
11602 <listOfReactants>
11603 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
11604 <speciesReference species="M_lys_L_e" stoichiometry="1.000000"/>
11605 </listOfReactants>
11606 <listOfProducts>
11607 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11608 <speciesReference species="M_lys_L_c" stoichiometry="1.000000"/>
11609 </listOfProducts>
11610 </reaction>
11611 <reaction id="R_L_LACD2" name="R_L_Lactate_dehydrogenase__ubiquinone_" reversible="false">
11612 <notes>
11613 <html:p>GENE_ASSOCIATION: b3605</html:p>
11614 <html:p>PROTEIN_ASSOCIATION: LldD</html:p>
11615 <html:p>SUBSYSTEM: S_</html:p>
11616 <html:p>PROTEIN_CLASS: 1.1.2.3</html:p>
11617 </notes>
11618 <listOfReactants>
11619 <speciesReference species="M_lac_L_c" stoichiometry="1.000000"/>
11620 <speciesReference species="M_q8_c" stoichiometry="1.000000"/>
11621 </listOfReactants>
11622 <listOfProducts>
11623 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
11624 <speciesReference species="M_q8h2_c" stoichiometry="1.000000"/>
11625 </listOfProducts>
11626 </reaction>
11627 <reaction id="R_L_LACD3" name="R_L_Lactate_dehydrogenase__menaquinone_" reversible="false">
11628 <notes>
11629 <html:p>GENE_ASSOCIATION: b3605</html:p>
11630 <html:p>PROTEIN_ASSOCIATION: LldD</html:p>
11631 <html:p>SUBSYSTEM: S_</html:p>
11632 <html:p>PROTEIN_CLASS: 1.1.2.3</html:p>
11633 </notes>
11634 <listOfReactants>
11635 <speciesReference species="M_lac_L_c" stoichiometry="1.000000"/>
11636 <speciesReference species="M_mqn8_c" stoichiometry="1.000000"/>
11637 </listOfReactants>
11638 <listOfProducts>
11639 <speciesReference species="M_mql8_c" stoichiometry="1.000000"/>
11640 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
11641 </listOfProducts>
11642 </reaction>
11643 <reaction id="R_L_LACt2r" name="R_L_lactate_reversible_transport_via_proton_symport" reversible="true">
11644 <notes>
11645 <html:p>GENE_ASSOCIATION: ( b3603 or b2975 )</html:p>
11646 <html:p>PROTEIN_ASSOCIATION: ( LldP ) or ( GlcA )</html:p>
11647 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
11648 <html:p>PROTEIN_CLASS: </html:p>
11649 </notes>
11650 <listOfReactants>
11651 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
11652 <speciesReference species="M_lac_L_e" stoichiometry="1.000000"/>
11653 </listOfReactants>
11654 <listOfProducts>
11655 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11656 <speciesReference species="M_lac_L_c" stoichiometry="1.000000"/>
11657 </listOfProducts>
11658 </reaction>
11659 <reaction id="R_M1PD" name="R_mannitol_1_phosphate_5_dehydrogenase" reversible="true">
11660 <notes>
11661 <html:p>GENE_ASSOCIATION: b3600</html:p>
11662 <html:p>PROTEIN_ASSOCIATION: MtlD</html:p>
11663 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
11664 <html:p>PROTEIN_CLASS: 1.1.1.17</html:p>
11665 </notes>
11666 <listOfReactants>
11667 <speciesReference species="M_mnl1p_c" stoichiometry="1.000000"/>
11668 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
11669 </listOfReactants>
11670 <listOfProducts>
11671 <speciesReference species="M_f6p_c" stoichiometry="1.000000"/>
11672 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11673 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
11674 </listOfProducts>
11675 </reaction>
11676 <reaction id="R_MACPD" name="R_Malonyl_ACP_decarboxylase" reversible="false">
11677 <notes>
11678 <html:p>GENE_ASSOCIATION: b2323</html:p>
11679 <html:p>PROTEIN_ASSOCIATION: FabB</html:p>
11680 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
11681 <html:p>PROTEIN_CLASS: </html:p>
11682 </notes>
11683 <listOfReactants>
11684 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11685 <speciesReference species="M_malACP_c" stoichiometry="1.000000"/>
11686 </listOfReactants>
11687 <listOfProducts>
11688 <speciesReference species="M_acACP_c" stoichiometry="1.000000"/>
11689 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
11690 </listOfProducts>
11691 </reaction>
11692 <reaction id="R_MALS" name="R_malate_synthase" reversible="false">
11693 <notes>
11694 <html:p>GENE_ASSOCIATION: ( b4014 or b2976 )</html:p>
11695 <html:p>PROTEIN_ASSOCIATION: ( AceB ) or ( GlcB )</html:p>
11696 <html:p>SUBSYSTEM: S_Anaplerotic_reactions</html:p>
11697 <html:p>PROTEIN_CLASS: 4.1.3.2</html:p>
11698 </notes>
11699 <listOfReactants>
11700 <speciesReference species="M_accoa_c" stoichiometry="1.000000"/>
11701 <speciesReference species="M_glx_c" stoichiometry="1.000000"/>
11702 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
11703 </listOfReactants>
11704 <listOfProducts>
11705 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
11706 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11707 <speciesReference species="M_mal_L_c" stoichiometry="1.000000"/>
11708 </listOfProducts>
11709 </reaction>
11710 <reaction id="R_MALTHXabc" name="R_maltohexaose_transport_via_ABC_system" reversible="false">
11711 <notes>
11712 <html:p>GENE_ASSOCIATION: ( b4036 and b4034 and b4033 and b4032 and b4035 )</html:p>
11713 <html:p>PROTEIN_ASSOCIATION: ( LamB and MalE and MalF and MalG and MalK )</html:p>
11714 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
11715 <html:p>PROTEIN_CLASS: </html:p>
11716 </notes>
11717 <listOfReactants>
11718 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
11719 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
11720 <speciesReference species="M_malthx_e" stoichiometry="1.000000"/>
11721 </listOfReactants>
11722 <listOfProducts>
11723 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
11724 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11725 <speciesReference species="M_malthx_c" stoichiometry="1.000000"/>
11726 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
11727 </listOfProducts>
11728 </reaction>
11729 <reaction id="R_MALTPTabc" name="R_maltopentaose_transport_via_ABC_system" reversible="false">
11730 <notes>
11731 <html:p>GENE_ASSOCIATION: ( b4036 and b4034 and b4033 and b4032 and b4035 )</html:p>
11732 <html:p>PROTEIN_ASSOCIATION: ( LamB and MalE and MalF and MalG and MalK )</html:p>
11733 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
11734 <html:p>PROTEIN_CLASS: </html:p>
11735 </notes>
11736 <listOfReactants>
11737 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
11738 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
11739 <speciesReference species="M_maltpt_e" stoichiometry="1.000000"/>
11740 </listOfReactants>
11741 <listOfProducts>
11742 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
11743 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11744 <speciesReference species="M_maltpt_c" stoichiometry="1.000000"/>
11745 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
11746 </listOfProducts>
11747 </reaction>
11748 <reaction id="R_MALTTRabc" name="R_Maltotriose_transport_via_ABC_system" reversible="false">
11749 <notes>
11750 <html:p>GENE_ASSOCIATION: ( b4036 and b4034 and b4033 and b4032 and b4035 )</html:p>
11751 <html:p>PROTEIN_ASSOCIATION: ( LamB and MalE and MalF and MalG and MalK )</html:p>
11752 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
11753 <html:p>PROTEIN_CLASS: </html:p>
11754 </notes>
11755 <listOfReactants>
11756 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
11757 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
11758 <speciesReference species="M_malttr_e" stoichiometry="1.000000"/>
11759 </listOfReactants>
11760 <listOfProducts>
11761 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
11762 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11763 <speciesReference species="M_malttr_c" stoichiometry="1.000000"/>
11764 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
11765 </listOfProducts>
11766 </reaction>
11767 <reaction id="R_MALTTTRabc" name="R_maltotetraose_transport_via_ABC_system" reversible="false">
11768 <notes>
11769 <html:p>GENE_ASSOCIATION: ( b4036 and b4034 and b4033 and b4032 and b4035 )</html:p>
11770 <html:p>PROTEIN_ASSOCIATION: ( LamB and MalE and MalF and MalG and MalK )</html:p>
11771 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
11772 <html:p>PROTEIN_CLASS: </html:p>
11773 </notes>
11774 <listOfReactants>
11775 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
11776 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
11777 <speciesReference species="M_maltttr_e" stoichiometry="1.000000"/>
11778 </listOfReactants>
11779 <listOfProducts>
11780 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
11781 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11782 <speciesReference species="M_maltttr_c" stoichiometry="1.000000"/>
11783 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
11784 </listOfProducts>
11785 </reaction>
11786 <reaction id="R_MALTabc" name="R_maltose_transport_via_ABC_system" reversible="false">
11787 <notes>
11788 <html:p>GENE_ASSOCIATION: ( b4036 and b4034 and b4033 and b4032 and b4035 )</html:p>
11789 <html:p>PROTEIN_ASSOCIATION: ( LamB and MalE and MalF and MalG and MalK )</html:p>
11790 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
11791 <html:p>PROTEIN_CLASS: </html:p>
11792 </notes>
11793 <listOfReactants>
11794 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
11795 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
11796 <speciesReference species="M_malt_e" stoichiometry="1.000000"/>
11797 </listOfReactants>
11798 <listOfProducts>
11799 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
11800 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11801 <speciesReference species="M_malt_c" stoichiometry="1.000000"/>
11802 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
11803 </listOfProducts>
11804 </reaction>
11805 <reaction id="R_MALTpts" name="R_maltose_transport_via_PEPPyr_PTS" reversible="false">
11806 <notes>
11807 <html:p>GENE_ASSOCIATION: ( b2417 and b4036 and b1621 and b2415 and b2416 )</html:p>
11808 <html:p>PROTEIN_ASSOCIATION: ( Crr and LamB and MalX and PtsH and PtsI )</html:p>
11809 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
11810 <html:p>PROTEIN_CLASS: </html:p>
11811 </notes>
11812 <listOfReactants>
11813 <speciesReference species="M_pep_c" stoichiometry="1.000000"/>
11814 <speciesReference species="M_malt_e" stoichiometry="1.000000"/>
11815 </listOfReactants>
11816 <listOfProducts>
11817 <speciesReference species="M_malt6p_c" stoichiometry="1.000000"/>
11818 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
11819 </listOfProducts>
11820 </reaction>
11821 <reaction id="R_MALt2_2" name="R_Malate_transport_via_proton_symport__2_H_" reversible="false">
11822 <notes>
11823 <html:p>GENE_ASSOCIATION: b3528</html:p>
11824 <html:p>PROTEIN_ASSOCIATION: DctA</html:p>
11825 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
11826 <html:p>PROTEIN_CLASS: </html:p>
11827 </notes>
11828 <listOfReactants>
11829 <speciesReference species="M_h_e" stoichiometry="2.000000"/>
11830 <speciesReference species="M_mal_L_e" stoichiometry="1.000000"/>
11831 </listOfReactants>
11832 <listOfProducts>
11833 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
11834 <speciesReference species="M_mal_L_c" stoichiometry="1.000000"/>
11835 </listOfProducts>
11836 </reaction>
11837 <reaction id="R_MALt2_3" name="R_Malate_transport_via_proton_symport__3_H_" reversible="false">
11838 <notes>
11839 <html:p>GENE_ASSOCIATION: ( b4138 or b4123 )</html:p>
11840 <html:p>PROTEIN_ASSOCIATION: ( DcuA ) or ( DcuB )</html:p>
11841 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
11842 <html:p>PROTEIN_CLASS: </html:p>
11843 </notes>
11844 <listOfReactants>
11845 <speciesReference species="M_h_e" stoichiometry="3.000000"/>
11846 <speciesReference species="M_mal_L_e" stoichiometry="1.000000"/>
11847 </listOfReactants>
11848 <listOfProducts>
11849 <speciesReference species="M_h_c" stoichiometry="3.000000"/>
11850 <speciesReference species="M_mal_L_c" stoichiometry="1.000000"/>
11851 </listOfProducts>
11852 </reaction>
11853 <reaction id="R_MAN1PT2" name="R_mannose_1_phosphate_guanylyltransferase__GDP_" reversible="false">
11854 <notes>
11855 <html:p>GENE_ASSOCIATION: b2049</html:p>
11856 <html:p>PROTEIN_ASSOCIATION: ManC</html:p>
11857 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
11858 <html:p>PROTEIN_CLASS: 2.7.7.22</html:p>
11859 </notes>
11860 <listOfReactants>
11861 <speciesReference species="M_gdp_c" stoichiometry="1.000000"/>
11862 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11863 <speciesReference species="M_man1p_c" stoichiometry="1.000000"/>
11864 </listOfReactants>
11865 <listOfProducts>
11866 <speciesReference species="M_gdpmann_c" stoichiometry="1.000000"/>
11867 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
11868 </listOfProducts>
11869 </reaction>
11870 <reaction id="R_MAN6PI" name="R_mannose_6_phosphate_isomerase" reversible="true">
11871 <notes>
11872 <html:p>GENE_ASSOCIATION: b1613</html:p>
11873 <html:p>PROTEIN_ASSOCIATION: ManA</html:p>
11874 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
11875 <html:p>PROTEIN_CLASS: 5.3.1.8</html:p>
11876 </notes>
11877 <listOfReactants>
11878 <speciesReference species="M_man6p_c" stoichiometry="1.000000"/>
11879 </listOfReactants>
11880 <listOfProducts>
11881 <speciesReference species="M_f6p_c" stoichiometry="1.000000"/>
11882 </listOfProducts>
11883 </reaction>
11884 <reaction id="R_MAN6Pt6_2" name="R_Mannose_6_phosphate_transport_via_phosphate_antiport" reversible="false">
11885 <notes>
11886 <html:p>GENE_ASSOCIATION: b3666</html:p>
11887 <html:p>PROTEIN_ASSOCIATION: UhpT</html:p>
11888 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
11889 <html:p>PROTEIN_CLASS: </html:p>
11890 </notes>
11891 <listOfReactants>
11892 <speciesReference species="M_pi_c" stoichiometry="2.000000"/>
11893 <speciesReference species="M_man6p_e" stoichiometry="1.000000"/>
11894 </listOfReactants>
11895 <listOfProducts>
11896 <speciesReference species="M_man6p_c" stoichiometry="1.000000"/>
11897 <speciesReference species="M_pi_e" stoichiometry="2.000000"/>
11898 </listOfProducts>
11899 </reaction>
11900 <reaction id="R_MANAO" name="R_Mannonate_oxidoreductase" reversible="true">
11901 <notes>
11902 <html:p>GENE_ASSOCIATION: b4323</html:p>
11903 <html:p>PROTEIN_ASSOCIATION: UxuB</html:p>
11904 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
11905 <html:p>PROTEIN_CLASS: 1.1.1.57</html:p>
11906 </notes>
11907 <listOfReactants>
11908 <speciesReference species="M_mana_c" stoichiometry="1.000000"/>
11909 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
11910 </listOfReactants>
11911 <listOfProducts>
11912 <speciesReference species="M_fruur_c" stoichiometry="1.000000"/>
11913 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11914 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
11915 </listOfProducts>
11916 </reaction>
11917 <reaction id="R_MANpts" name="R_D_mannose_transport_via_PEPPyr_PTS" reversible="false">
11918 <notes>
11919 <html:p>GENE_ASSOCIATION: ( b1817 and b1818 and b1819 and b2415 and b2416 )</html:p>
11920 <html:p>PROTEIN_ASSOCIATION: ( ManX and ManY and ManZ and PtsH and PtsI )</html:p>
11921 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
11922 <html:p>PROTEIN_CLASS: </html:p>
11923 </notes>
11924 <listOfReactants>
11925 <speciesReference species="M_pep_c" stoichiometry="1.000000"/>
11926 <speciesReference species="M_man_e" stoichiometry="1.000000"/>
11927 </listOfReactants>
11928 <listOfProducts>
11929 <speciesReference species="M_man6p_c" stoichiometry="1.000000"/>
11930 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
11931 </listOfProducts>
11932 </reaction>
11933 <reaction id="R_MCITD" name="R_2_methylcitrate_dehydratase" reversible="false">
11934 <notes>
11935 <html:p>GENE_ASSOCIATION: b0334</html:p>
11936 <html:p>PROTEIN_ASSOCIATION: PrpD</html:p>
11937 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
11938 <html:p>PROTEIN_CLASS: 4.2.1.79</html:p>
11939 </notes>
11940 <listOfReactants>
11941 <speciesReference species="M_2mcit_c" stoichiometry="1.000000"/>
11942 </listOfReactants>
11943 <listOfProducts>
11944 <speciesReference species="M_2mcacn_c" stoichiometry="1.000000"/>
11945 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
11946 </listOfProducts>
11947 </reaction>
11948 <reaction id="R_MCITL2" name="R_methylisocitrate_lyase" reversible="true">
11949 <notes>
11950 <html:p>GENE_ASSOCIATION: b0331</html:p>
11951 <html:p>PROTEIN_ASSOCIATION: PrpB</html:p>
11952 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
11953 <html:p>PROTEIN_CLASS: 4.1.3.30</html:p>
11954 </notes>
11955 <listOfReactants>
11956 <speciesReference species="M_micit_c" stoichiometry="1.000000"/>
11957 </listOfReactants>
11958 <listOfProducts>
11959 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
11960 <speciesReference species="M_succ_c" stoichiometry="1.000000"/>
11961 </listOfProducts>
11962 </reaction>
11963 <reaction id="R_MCITS" name="R_2_methylcitrate_synthase" reversible="false">
11964 <notes>
11965 <html:p>GENE_ASSOCIATION: b0333</html:p>
11966 <html:p>PROTEIN_ASSOCIATION: PrpC</html:p>
11967 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
11968 <html:p>PROTEIN_CLASS: 4.1.3.31</html:p>
11969 </notes>
11970 <listOfReactants>
11971 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
11972 <speciesReference species="M_oaa_c" stoichiometry="1.000000"/>
11973 <speciesReference species="M_ppcoa_c" stoichiometry="1.000000"/>
11974 </listOfReactants>
11975 <listOfProducts>
11976 <speciesReference species="M_2mcit_c" stoichiometry="1.000000"/>
11977 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
11978 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
11979 </listOfProducts>
11980 </reaction>
11981 <reaction id="R_MCOATA" name="R_Malonyl_CoA_ACP_transacylase" reversible="true">
11982 <notes>
11983 <html:p>GENE_ASSOCIATION: b1092</html:p>
11984 <html:p>PROTEIN_ASSOCIATION: FabD</html:p>
11985 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
11986 <html:p>PROTEIN_CLASS: 2.3.1.39</html:p>
11987 </notes>
11988 <listOfReactants>
11989 <speciesReference species="M_ACP_c" stoichiometry="1.000000"/>
11990 <speciesReference species="M_malcoa_c" stoichiometry="1.000000"/>
11991 </listOfReactants>
11992 <listOfProducts>
11993 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
11994 <speciesReference species="M_malACP_c" stoichiometry="1.000000"/>
11995 </listOfProducts>
11996 </reaction>
11997 <reaction id="R_MDH" name="R_malate_dehydrogenase" reversible="true">
11998 <notes>
11999 <html:p>GENE_ASSOCIATION: b3236</html:p>
12000 <html:p>PROTEIN_ASSOCIATION: Mdh</html:p>
12001 <html:p>SUBSYSTEM: S_Citric_Acid_Cycle</html:p>
12002 <html:p>PROTEIN_CLASS: 1.1.1.37</html:p>
12003 </notes>
12004 <listOfReactants>
12005 <speciesReference species="M_mal_L_c" stoichiometry="1.000000"/>
12006 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
12007 </listOfReactants>
12008 <listOfProducts>
12009 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
12010 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
12011 <speciesReference species="M_oaa_c" stoichiometry="1.000000"/>
12012 </listOfProducts>
12013 </reaction>
12014 <reaction id="R_MDH2" name="R_Malate_dehydrogenase__ubiquinone_8_as_acceptor_" reversible="false">
12015 <notes>
12016 <html:p>GENE_ASSOCIATION: b2210</html:p>
12017 <html:p>PROTEIN_ASSOCIATION: Mqo</html:p>
12018 <html:p>SUBSYSTEM: S_Citric_Acid_Cycle</html:p>
12019 <html:p>PROTEIN_CLASS: 1.1.99.16</html:p>
12020 </notes>
12021 <listOfReactants>
12022 <speciesReference species="M_mal_L_c" stoichiometry="1.000000"/>
12023 <speciesReference species="M_q8_c" stoichiometry="1.000000"/>
12024 </listOfReactants>
12025 <listOfProducts>
12026 <speciesReference species="M_oaa_c" stoichiometry="1.000000"/>
12027 <speciesReference species="M_q8h2_c" stoichiometry="1.000000"/>
12028 </listOfProducts>
12029 </reaction>
12030 <reaction id="R_MDH3" name="R_Malate_dehydrogenase__menaquinone_8_as_acceptor_" reversible="false">
12031 <notes>
12032 <html:p>GENE_ASSOCIATION: b2210</html:p>
12033 <html:p>PROTEIN_ASSOCIATION: Mqo</html:p>
12034 <html:p>SUBSYSTEM: S_Citric_Acid_Cycle</html:p>
12035 <html:p>PROTEIN_CLASS: 1.1.99.16</html:p>
12036 </notes>
12037 <listOfReactants>
12038 <speciesReference species="M_mal_L_c" stoichiometry="1.000000"/>
12039 <speciesReference species="M_mqn8_c" stoichiometry="1.000000"/>
12040 </listOfReactants>
12041 <listOfProducts>
12042 <speciesReference species="M_mql8_c" stoichiometry="1.000000"/>
12043 <speciesReference species="M_oaa_c" stoichiometry="1.000000"/>
12044 </listOfProducts>
12045 </reaction>
12046 <reaction id="R_MDRPD" name="R_5_Methylthio_5_deoxy_D_ribulose_1_phosphate_dehydratase" reversible="false">
12047 <notes>
12048 <html:p>GENE_ASSOCIATION: </html:p>
12049 <html:p>PROTEIN_ASSOCIATION: </html:p>
12050 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
12051 <html:p>PROTEIN_CLASS: </html:p>
12052 </notes>
12053 <listOfReactants>
12054 <speciesReference species="M_5mdru1p_c" stoichiometry="1.000000"/>
12055 </listOfReactants>
12056 <listOfProducts>
12057 <speciesReference species="M_dkmpp_c" stoichiometry="1.000000"/>
12058 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
12059 </listOfProducts>
12060 </reaction>
12061 <reaction id="R_ME1" name="R_malic_enzyme__NAD_" reversible="false">
12062 <notes>
12063 <html:p>GENE_ASSOCIATION: b1479</html:p>
12064 <html:p>PROTEIN_ASSOCIATION: Sfc</html:p>
12065 <html:p>SUBSYSTEM: S_Anaplerotic_reactions</html:p>
12066 <html:p>PROTEIN_CLASS: 1.1.1.38</html:p>
12067 </notes>
12068 <listOfReactants>
12069 <speciesReference species="M_mal_L_c" stoichiometry="1.000000"/>
12070 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
12071 </listOfReactants>
12072 <listOfProducts>
12073 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
12074 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
12075 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
12076 </listOfProducts>
12077 </reaction>
12078 <reaction id="R_ME2" name="R_malic_enzyme__NADP_" reversible="false">
12079 <notes>
12080 <html:p>GENE_ASSOCIATION: b2463</html:p>
12081 <html:p>PROTEIN_ASSOCIATION: Mae</html:p>
12082 <html:p>SUBSYSTEM: S_Anaplerotic_reactions</html:p>
12083 <html:p>PROTEIN_CLASS: 1.1.1.40</html:p>
12084 </notes>
12085 <listOfReactants>
12086 <speciesReference species="M_mal_L_c" stoichiometry="1.000000"/>
12087 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
12088 </listOfReactants>
12089 <listOfProducts>
12090 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
12091 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
12092 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
12093 </listOfProducts>
12094 </reaction>
12095 <reaction id="R_MECDPDH" name="R_2C_methyl_D_erythritol_2_4_cyclodiphosphate_dehydratase" reversible="false">
12096 <notes>
12097 <html:p>GENE_ASSOCIATION: b2515</html:p>
12098 <html:p>PROTEIN_ASSOCIATION: GcpE</html:p>
12099 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
12100 <html:p>PROTEIN_CLASS: </html:p>
12101 </notes>
12102 <listOfReactants>
12103 <speciesReference species="M_2mecdp_c" stoichiometry="1.000000"/>
12104 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
12105 </listOfReactants>
12106 <listOfProducts>
12107 <speciesReference species="M_h2mb4p_c" stoichiometry="1.000000"/>
12108 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
12109 </listOfProducts>
12110 </reaction>
12111 <reaction id="R_MECDPS" name="R_2_C_methyl_D_erythritol_2_4_cyclodiphosphate_synthase" reversible="false">
12112 <notes>
12113 <html:p>GENE_ASSOCIATION: b2746</html:p>
12114 <html:p>PROTEIN_ASSOCIATION: IspF</html:p>
12115 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
12116 <html:p>PROTEIN_CLASS: </html:p>
12117 </notes>
12118 <listOfReactants>
12119 <speciesReference species="M_2p4c2me_c" stoichiometry="1.000000"/>
12120 </listOfReactants>
12121 <listOfProducts>
12122 <speciesReference species="M_2mecdp_c" stoichiometry="1.000000"/>
12123 <speciesReference species="M_cmp_c" stoichiometry="1.000000"/>
12124 </listOfProducts>
12125 </reaction>
12126 <reaction id="R_MELIBt2" name="R_melibiose_transport_in_via_symport" reversible="false">
12127 <notes>
12128 <html:p>GENE_ASSOCIATION: b4120</html:p>
12129 <html:p>PROTEIN_ASSOCIATION: MelB</html:p>
12130 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
12131 <html:p>PROTEIN_CLASS: </html:p>
12132 </notes>
12133 <listOfReactants>
12134 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
12135 <speciesReference species="M_melib_e" stoichiometry="1.000000"/>
12136 </listOfReactants>
12137 <listOfProducts>
12138 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
12139 <speciesReference species="M_melib_c" stoichiometry="1.000000"/>
12140 </listOfProducts>
12141 </reaction>
12142 <reaction id="R_MEPCT" name="R_2_C_methyl_D_erythritol_4_phosphate_cytidylyltransferase" reversible="false">
12143 <notes>
12144 <html:p>GENE_ASSOCIATION: b2747</html:p>
12145 <html:p>PROTEIN_ASSOCIATION: IspD</html:p>
12146 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
12147 <html:p>PROTEIN_CLASS: </html:p>
12148 </notes>
12149 <listOfReactants>
12150 <speciesReference species="M_2me4p_c" stoichiometry="1.000000"/>
12151 <speciesReference species="M_ctp_c" stoichiometry="1.000000"/>
12152 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
12153 </listOfReactants>
12154 <listOfProducts>
12155 <speciesReference species="M_4c2me_c" stoichiometry="1.000000"/>
12156 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
12157 </listOfProducts>
12158 </reaction>
12159 <reaction id="R_METAT" name="R_methionine_adenosyltransferase" reversible="false">
12160 <notes>
12161 <html:p>GENE_ASSOCIATION: b2942</html:p>
12162 <html:p>PROTEIN_ASSOCIATION: MetK</html:p>
12163 <html:p>SUBSYSTEM: S_Methionine_Metabolism</html:p>
12164 <html:p>PROTEIN_CLASS: 2.5.1.6</html:p>
12165 </notes>
12166 <listOfReactants>
12167 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
12168 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
12169 <speciesReference species="M_met_L_c" stoichiometry="1.000000"/>
12170 </listOfReactants>
12171 <listOfProducts>
12172 <speciesReference species="M_amet_c" stoichiometry="1.000000"/>
12173 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
12174 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
12175 </listOfProducts>
12176 </reaction>
12177 <reaction id="R_METDabc" name="R_D_methionine_transport_via_ABC_system" reversible="false">
12178 <notes>
12179 <html:p>GENE_ASSOCIATION: ( b0198 and b0199 and b0197 )</html:p>
12180 <html:p>PROTEIN_ASSOCIATION: ( MetI and MetN and MetQ )</html:p>
12181 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
12182 <html:p>PROTEIN_CLASS: </html:p>
12183 </notes>
12184 <listOfReactants>
12185 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
12186 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
12187 <speciesReference species="M_met_D_e" stoichiometry="1.000000"/>
12188 </listOfReactants>
12189 <listOfProducts>
12190 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
12191 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
12192 <speciesReference species="M_met_D_c" stoichiometry="1.000000"/>
12193 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
12194 </listOfProducts>
12195 </reaction>
12196 <reaction id="R_METS" name="R_methionine_synthase" reversible="false">
12197 <notes>
12198 <html:p>GENE_ASSOCIATION: ( b4019 or b3829 )</html:p>
12199 <html:p>PROTEIN_ASSOCIATION: ( MetH ) or ( MetE )</html:p>
12200 <html:p>SUBSYSTEM: S_Methionine_Metabolism</html:p>
12201 <html:p>PROTEIN_CLASS: 2.1.1.13</html:p>
12202 </notes>
12203 <listOfReactants>
12204 <speciesReference species="M_5mthf_c" stoichiometry="1.000000"/>
12205 <speciesReference species="M_hcys_L_c" stoichiometry="1.000000"/>
12206 </listOfReactants>
12207 <listOfProducts>
12208 <speciesReference species="M_met_L_c" stoichiometry="1.000000"/>
12209 <speciesReference species="M_thf_c" stoichiometry="1.000000"/>
12210 </listOfProducts>
12211 </reaction>
12212 <reaction id="R_METabc" name="R_L_methionine_transport_via_ABC_system" reversible="false">
12213 <notes>
12214 <html:p>GENE_ASSOCIATION: ( b0198 and b0199 and b0197 )</html:p>
12215 <html:p>PROTEIN_ASSOCIATION: ( MetI and MetN and MetQ )</html:p>
12216 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
12217 <html:p>PROTEIN_CLASS: </html:p>
12218 </notes>
12219 <listOfReactants>
12220 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
12221 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
12222 <speciesReference species="M_met_L_e" stoichiometry="1.000000"/>
12223 </listOfReactants>
12224 <listOfProducts>
12225 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
12226 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
12227 <speciesReference species="M_met_L_c" stoichiometry="1.000000"/>
12228 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
12229 </listOfProducts>
12230 </reaction>
12231 <reaction id="R_MGSA" name="R_methylglyoxal_synthase" reversible="false">
12232 <notes>
12233 <html:p>GENE_ASSOCIATION: b0963</html:p>
12234 <html:p>PROTEIN_ASSOCIATION: MgsA</html:p>
12235 <html:p>SUBSYSTEM: S_Methylglyoxal_Metabolism</html:p>
12236 <html:p>PROTEIN_CLASS: 4.2.3.3</html:p>
12237 </notes>
12238 <listOfReactants>
12239 <speciesReference species="M_dhap_c" stoichiometry="1.000000"/>
12240 </listOfReactants>
12241 <listOfProducts>
12242 <speciesReference species="M_mthgxl_c" stoichiometry="1.000000"/>
12243 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
12244 </listOfProducts>
12245 </reaction>
12246 <reaction id="R_MI1PP" name="R_myo_inositol_1_phosphatase" reversible="false">
12247 <notes>
12248 <html:p>GENE_ASSOCIATION: b2533</html:p>
12249 <html:p>PROTEIN_ASSOCIATION: SuhB</html:p>
12250 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
12251 <html:p>PROTEIN_CLASS: 3.1.3.25</html:p>
12252 </notes>
12253 <listOfReactants>
12254 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
12255 <speciesReference species="M_mi1p_D_c" stoichiometry="1.000000"/>
12256 </listOfReactants>
12257 <listOfProducts>
12258 <speciesReference species="M_inost_c" stoichiometry="1.000000"/>
12259 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
12260 </listOfProducts>
12261 </reaction>
12262 <reaction id="R_MICITD" name="R_2_methylisocitrate_dehydratase" reversible="false">
12263 <notes>
12264 <html:p>GENE_ASSOCIATION: ( b1276 or b0118 )</html:p>
12265 <html:p>PROTEIN_ASSOCIATION: ( AcnA ) or ( AcnB )</html:p>
12266 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
12267 <html:p>PROTEIN_CLASS: 4.2.1.99</html:p>
12268 </notes>
12269 <listOfReactants>
12270 <speciesReference species="M_2mcacn_c" stoichiometry="1.000000"/>
12271 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
12272 </listOfReactants>
12273 <listOfProducts>
12274 <speciesReference species="M_micit_c" stoichiometry="1.000000"/>
12275 </listOfProducts>
12276 </reaction>
12277 <reaction id="R_MLTG1" name="R_Maltodextrin_glucosidase__maltotriose_" reversible="false">
12278 <notes>
12279 <html:p>GENE_ASSOCIATION: b0403</html:p>
12280 <html:p>PROTEIN_ASSOCIATION: MalZ</html:p>
12281 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
12282 <html:p>PROTEIN_CLASS: </html:p>
12283 </notes>
12284 <listOfReactants>
12285 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
12286 <speciesReference species="M_malttr_c" stoichiometry="1.000000"/>
12287 </listOfReactants>
12288 <listOfProducts>
12289 <speciesReference species="M_glc_D_c" stoichiometry="1.000000"/>
12290 <speciesReference species="M_malt_c" stoichiometry="1.000000"/>
12291 </listOfProducts>
12292 </reaction>
12293 <reaction id="R_MLTG2" name="R_Maltodextrin_glucosidase__maltotetraose_" reversible="false">
12294 <notes>
12295 <html:p>GENE_ASSOCIATION: b0403</html:p>
12296 <html:p>PROTEIN_ASSOCIATION: MalZ</html:p>
12297 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
12298 <html:p>PROTEIN_CLASS: </html:p>
12299 </notes>
12300 <listOfReactants>
12301 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
12302 <speciesReference species="M_maltttr_c" stoichiometry="1.000000"/>
12303 </listOfReactants>
12304 <listOfProducts>
12305 <speciesReference species="M_glc_D_c" stoichiometry="1.000000"/>
12306 <speciesReference species="M_malttr_c" stoichiometry="1.000000"/>
12307 </listOfProducts>
12308 </reaction>
12309 <reaction id="R_MLTG3" name="R_Maltodextrin_glucosidase__maltopentaose_" reversible="false">
12310 <notes>
12311 <html:p>GENE_ASSOCIATION: b0403</html:p>
12312 <html:p>PROTEIN_ASSOCIATION: MalZ</html:p>
12313 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
12314 <html:p>PROTEIN_CLASS: </html:p>
12315 </notes>
12316 <listOfReactants>
12317 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
12318 <speciesReference species="M_maltpt_c" stoichiometry="1.000000"/>
12319 </listOfReactants>
12320 <listOfProducts>
12321 <speciesReference species="M_glc_D_c" stoichiometry="1.000000"/>
12322 <speciesReference species="M_maltttr_c" stoichiometry="1.000000"/>
12323 </listOfProducts>
12324 </reaction>
12325 <reaction id="R_MLTG4" name="R_Maltodextrin_glucosidase__maltohexaose_" reversible="false">
12326 <notes>
12327 <html:p>GENE_ASSOCIATION: b0403</html:p>
12328 <html:p>PROTEIN_ASSOCIATION: MalZ</html:p>
12329 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
12330 <html:p>PROTEIN_CLASS: </html:p>
12331 </notes>
12332 <listOfReactants>
12333 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
12334 <speciesReference species="M_malthx_c" stoichiometry="1.000000"/>
12335 </listOfReactants>
12336 <listOfProducts>
12337 <speciesReference species="M_glc_D_c" stoichiometry="1.000000"/>
12338 <speciesReference species="M_maltpt_c" stoichiometry="1.000000"/>
12339 </listOfProducts>
12340 </reaction>
12341 <reaction id="R_MLTG5" name="R_Maltodextrin_glucosidase__maltoheptaose_" reversible="false">
12342 <notes>
12343 <html:p>GENE_ASSOCIATION: b0403</html:p>
12344 <html:p>PROTEIN_ASSOCIATION: MalZ</html:p>
12345 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
12346 <html:p>PROTEIN_CLASS: </html:p>
12347 </notes>
12348 <listOfReactants>
12349 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
12350 <speciesReference species="M_malthp_c" stoichiometry="1.000000"/>
12351 </listOfReactants>
12352 <listOfProducts>
12353 <speciesReference species="M_glc_D_c" stoichiometry="1.000000"/>
12354 <speciesReference species="M_malthx_c" stoichiometry="1.000000"/>
12355 </listOfProducts>
12356 </reaction>
12357 <reaction id="R_MLTP1" name="R_Maltodextrin_phosphorylase__maltopentaose_" reversible="true">
12358 <notes>
12359 <html:p>GENE_ASSOCIATION: b3417</html:p>
12360 <html:p>PROTEIN_ASSOCIATION: MalP</html:p>
12361 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
12362 <html:p>PROTEIN_CLASS: </html:p>
12363 </notes>
12364 <listOfReactants>
12365 <speciesReference species="M_maltpt_c" stoichiometry="1.000000"/>
12366 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
12367 </listOfReactants>
12368 <listOfProducts>
12369 <speciesReference species="M_g1p_c" stoichiometry="1.000000"/>
12370 <speciesReference species="M_maltttr_c" stoichiometry="1.000000"/>
12371 </listOfProducts>
12372 </reaction>
12373 <reaction id="R_MLTP2" name="R_Maltodextrin_phosphorylase__maltohexaose_" reversible="true">
12374 <notes>
12375 <html:p>GENE_ASSOCIATION: b3417</html:p>
12376 <html:p>PROTEIN_ASSOCIATION: MalP</html:p>
12377 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
12378 <html:p>PROTEIN_CLASS: </html:p>
12379 </notes>
12380 <listOfReactants>
12381 <speciesReference species="M_malthx_c" stoichiometry="1.000000"/>
12382 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
12383 </listOfReactants>
12384 <listOfProducts>
12385 <speciesReference species="M_g1p_c" stoichiometry="1.000000"/>
12386 <speciesReference species="M_maltpt_c" stoichiometry="1.000000"/>
12387 </listOfProducts>
12388 </reaction>
12389 <reaction id="R_MLTP3" name="R_Maltodextrin_phosphorylase__maltoheptaose_" reversible="true">
12390 <notes>
12391 <html:p>GENE_ASSOCIATION: b3417</html:p>
12392 <html:p>PROTEIN_ASSOCIATION: MalP</html:p>
12393 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
12394 <html:p>PROTEIN_CLASS: </html:p>
12395 </notes>
12396 <listOfReactants>
12397 <speciesReference species="M_malthp_c" stoichiometry="1.000000"/>
12398 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
12399 </listOfReactants>
12400 <listOfProducts>
12401 <speciesReference species="M_g1p_c" stoichiometry="1.000000"/>
12402 <speciesReference species="M_malthx_c" stoichiometry="1.000000"/>
12403 </listOfProducts>
12404 </reaction>
12405 <reaction id="R_MMCD" name="R_Methylmalonyl_CoA_decarboxylase" reversible="false">
12406 <notes>
12407 <html:p>GENE_ASSOCIATION: b2919</html:p>
12408 <html:p>PROTEIN_ASSOCIATION: YgfG</html:p>
12409 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
12410 <html:p>PROTEIN_CLASS: 4.1.1.41</html:p>
12411 </notes>
12412 <listOfReactants>
12413 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
12414 <speciesReference species="M_mmcoa_S_c" stoichiometry="1.000000"/>
12415 </listOfReactants>
12416 <listOfProducts>
12417 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
12418 <speciesReference species="M_ppcoa_c" stoichiometry="1.000000"/>
12419 </listOfProducts>
12420 </reaction>
12421 <reaction id="R_MME" name="R_methylmalonyl_CoA_epimerase" reversible="true">
12422 <notes>
12423 <html:p>GENE_ASSOCIATION: </html:p>
12424 <html:p>PROTEIN_ASSOCIATION: </html:p>
12425 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
12426 <html:p>PROTEIN_CLASS: 5.1.99.1</html:p>
12427 </notes>
12428 <listOfReactants>
12429 <speciesReference species="M_mmcoa_R_c" stoichiometry="1.000000"/>
12430 </listOfReactants>
12431 <listOfProducts>
12432 <speciesReference species="M_mmcoa_S_c" stoichiometry="1.000000"/>
12433 </listOfProducts>
12434 </reaction>
12435 <reaction id="R_MMM2" name="R_Methylmalonyl_CoA_mutase" reversible="false">
12436 <notes>
12437 <html:p>GENE_ASSOCIATION: b2917</html:p>
12438 <html:p>PROTEIN_ASSOCIATION: Sbm</html:p>
12439 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
12440 <html:p>PROTEIN_CLASS: 5.4.99.2</html:p>
12441 </notes>
12442 <listOfReactants>
12443 <speciesReference species="M_succoa_c" stoichiometry="1.000000"/>
12444 </listOfReactants>
12445 <listOfProducts>
12446 <speciesReference species="M_mmcoa_R_c" stoichiometry="1.000000"/>
12447 </listOfProducts>
12448 </reaction>
12449 <reaction id="R_MNLpts" name="R_mannitol_transport_via_PEPPyr_PTS" reversible="false">
12450 <notes>
12451 <html:p>GENE_ASSOCIATION: ( b3599 and b2415 and b2416 )</html:p>
12452 <html:p>PROTEIN_ASSOCIATION: ( MtlA and PtsH and PtsI )</html:p>
12453 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
12454 <html:p>PROTEIN_CLASS: </html:p>
12455 </notes>
12456 <listOfReactants>
12457 <speciesReference species="M_pep_c" stoichiometry="1.000000"/>
12458 <speciesReference species="M_mnl_e" stoichiometry="1.000000"/>
12459 </listOfReactants>
12460 <listOfProducts>
12461 <speciesReference species="M_mnl1p_c" stoichiometry="1.000000"/>
12462 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
12463 </listOfProducts>
12464 </reaction>
12465 <reaction id="R_MNNH" name="R_D_mannonate_hydrolyase" reversible="false">
12466 <notes>
12467 <html:p>GENE_ASSOCIATION: b4322</html:p>
12468 <html:p>PROTEIN_ASSOCIATION: UxuAec</html:p>
12469 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
12470 <html:p>PROTEIN_CLASS: 4.2.1.8</html:p>
12471 </notes>
12472 <listOfReactants>
12473 <speciesReference species="M_mana_c" stoichiometry="1.000000"/>
12474 </listOfReactants>
12475 <listOfProducts>
12476 <speciesReference species="M_2ddglcn_c" stoichiometry="1.000000"/>
12477 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
12478 </listOfProducts>
12479 </reaction>
12480 <reaction id="R_MOAT" name="R_3_deoxy_D_manno_octulosonic_acid_transferase" reversible="false">
12481 <notes>
12482 <html:p>GENE_ASSOCIATION: b3633</html:p>
12483 <html:p>PROTEIN_ASSOCIATION: KdtA</html:p>
12484 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
12485 <html:p>PROTEIN_CLASS: </html:p>
12486 </notes>
12487 <listOfReactants>
12488 <speciesReference species="M_ckdo_c" stoichiometry="1.000000"/>
12489 <speciesReference species="M_lipidA_c" stoichiometry="1.000000"/>
12490 </listOfReactants>
12491 <listOfProducts>
12492 <speciesReference species="M_cmp_c" stoichiometry="1.000000"/>
12493 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
12494 <speciesReference species="M_kdolipid4_c" stoichiometry="1.000000"/>
12495 </listOfProducts>
12496 </reaction>
12497 <reaction id="R_MOAT2" name="R_3_deoxy_D_manno_octulosonic_acid_transferase" reversible="false">
12498 <notes>
12499 <html:p>GENE_ASSOCIATION: b3633</html:p>
12500 <html:p>PROTEIN_ASSOCIATION: KdtA</html:p>
12501 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
12502 <html:p>PROTEIN_CLASS: </html:p>
12503 </notes>
12504 <listOfReactants>
12505 <speciesReference species="M_ckdo_c" stoichiometry="1.000000"/>
12506 <speciesReference species="M_kdolipid4_c" stoichiometry="1.000000"/>
12507 </listOfReactants>
12508 <listOfProducts>
12509 <speciesReference species="M_cmp_c" stoichiometry="1.000000"/>
12510 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
12511 <speciesReference species="M_kdo2lipid4_c" stoichiometry="1.000000"/>
12512 </listOfProducts>
12513 </reaction>
12514 <reaction id="R_MOHMT" name="R_3_methyl_2_oxobutanoate_hydroxymethyltransferase" reversible="false">
12515 <notes>
12516 <html:p>GENE_ASSOCIATION: b0134</html:p>
12517 <html:p>PROTEIN_ASSOCIATION: PanB</html:p>
12518 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
12519 <html:p>PROTEIN_CLASS: 2.1.2.11</html:p>
12520 </notes>
12521 <listOfReactants>
12522 <speciesReference species="M_3mob_c" stoichiometry="1.000000"/>
12523 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
12524 <speciesReference species="M_mlthf_c" stoichiometry="1.000000"/>
12525 </listOfReactants>
12526 <listOfProducts>
12527 <speciesReference species="M_2dhp_c" stoichiometry="1.000000"/>
12528 <speciesReference species="M_thf_c" stoichiometry="1.000000"/>
12529 </listOfProducts>
12530 </reaction>
12531 <reaction id="R_MTAN" name="R_methylthioadenosine_nucleosidase" reversible="false">
12532 <notes>
12533 <html:p>GENE_ASSOCIATION: b0159</html:p>
12534 <html:p>PROTEIN_ASSOCIATION: Mtn</html:p>
12535 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
12536 <html:p>PROTEIN_CLASS: 3.2.2.16</html:p>
12537 </notes>
12538 <listOfReactants>
12539 <speciesReference species="M_5mta_c" stoichiometry="1.000000"/>
12540 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
12541 </listOfReactants>
12542 <listOfProducts>
12543 <speciesReference species="M_5mtr_c" stoichiometry="1.000000"/>
12544 <speciesReference species="M_ade_c" stoichiometry="1.000000"/>
12545 </listOfProducts>
12546 </reaction>
12547 <reaction id="R_MTHFC" name="R_methenyltetrahydrofolate_cyclohydrolase" reversible="true">
12548 <notes>
12549 <html:p>GENE_ASSOCIATION: b0529</html:p>
12550 <html:p>PROTEIN_ASSOCIATION: FolD</html:p>
12551 <html:p>SUBSYSTEM: S_Folate_Metabolism</html:p>
12552 <html:p>PROTEIN_CLASS: 3.5.4.9</html:p>
12553 </notes>
12554 <listOfReactants>
12555 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
12556 <speciesReference species="M_methf_c" stoichiometry="1.000000"/>
12557 </listOfReactants>
12558 <listOfProducts>
12559 <speciesReference species="M_10fthf_c" stoichiometry="1.000000"/>
12560 </listOfProducts>
12561 </reaction>
12562 <reaction id="R_MTHFD" name="R_methylenetetrahydrofolate_dehydrogenase__NADP_" reversible="true">
12563 <notes>
12564 <html:p>GENE_ASSOCIATION: b0529</html:p>
12565 <html:p>PROTEIN_ASSOCIATION: FolD</html:p>
12566 <html:p>SUBSYSTEM: S_Folate_Metabolism</html:p>
12567 <html:p>PROTEIN_CLASS: 1.5.1.5</html:p>
12568 </notes>
12569 <listOfReactants>
12570 <speciesReference species="M_mlthf_c" stoichiometry="1.000000"/>
12571 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
12572 </listOfReactants>
12573 <listOfProducts>
12574 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
12575 <speciesReference species="M_methf_c" stoichiometry="1.000000"/>
12576 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
12577 </listOfProducts>
12578 </reaction>
12579 <reaction id="R_MTHFR2" name="R_5_10_methylenetetrahydrofolate_reductase__NADH_" reversible="false">
12580 <notes>
12581 <html:p>GENE_ASSOCIATION: b3941</html:p>
12582 <html:p>PROTEIN_ASSOCIATION: MetF</html:p>
12583 <html:p>SUBSYSTEM: S_Folate_Metabolism</html:p>
12584 <html:p>PROTEIN_CLASS: </html:p>
12585 </notes>
12586 <listOfReactants>
12587 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
12588 <speciesReference species="M_mlthf_c" stoichiometry="1.000000"/>
12589 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
12590 </listOfReactants>
12591 <listOfProducts>
12592 <speciesReference species="M_5mthf_c" stoichiometry="1.000000"/>
12593 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
12594 </listOfProducts>
12595 </reaction>
12596 <reaction id="R_MTRI" name="R_5_methylthioribose_1_phosphate_isomerase" reversible="true">
12597 <notes>
12598 <html:p>GENE_ASSOCIATION: </html:p>
12599 <html:p>PROTEIN_ASSOCIATION: </html:p>
12600 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
12601 <html:p>PROTEIN_CLASS: 5.3.1.23</html:p>
12602 </notes>
12603 <listOfReactants>
12604 <speciesReference species="M_5mdr1p_c" stoichiometry="1.000000"/>
12605 </listOfReactants>
12606 <listOfProducts>
12607 <speciesReference species="M_5mdru1p_c" stoichiometry="1.000000"/>
12608 </listOfProducts>
12609 </reaction>
12610 <reaction id="R_MTRK" name="R_5_methylthioribose_kinase" reversible="false">
12611 <notes>
12612 <html:p>GENE_ASSOCIATION: </html:p>
12613 <html:p>PROTEIN_ASSOCIATION: </html:p>
12614 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
12615 <html:p>PROTEIN_CLASS: 2.7.1.100</html:p>
12616 </notes>
12617 <listOfReactants>
12618 <speciesReference species="M_5mtr_c" stoichiometry="1.000000"/>
12619 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
12620 </listOfReactants>
12621 <listOfProducts>
12622 <speciesReference species="M_5mdr1p_c" stoichiometry="1.000000"/>
12623 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
12624 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
12625 </listOfProducts>
12626 </reaction>
12627 <reaction id="R_NACODA" name="R_N_acetylornithine_deacetylase" reversible="false">
12628 <notes>
12629 <html:p>GENE_ASSOCIATION: b3957</html:p>
12630 <html:p>PROTEIN_ASSOCIATION: ArgE</html:p>
12631 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
12632 <html:p>PROTEIN_CLASS: </html:p>
12633 </notes>
12634 <listOfReactants>
12635 <speciesReference species="M_acg5sa_c" stoichiometry="1.000000"/>
12636 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
12637 </listOfReactants>
12638 <listOfProducts>
12639 <speciesReference species="M_ac_c" stoichiometry="1.000000"/>
12640 <speciesReference species="M_glu5sa_c" stoichiometry="1.000000"/>
12641 </listOfProducts>
12642 </reaction>
12643 <reaction id="R_NACUP" name="R_Nicotinic_acid_uptake" reversible="false">
12644 <notes>
12645 <html:p>GENE_ASSOCIATION: </html:p>
12646 <html:p>PROTEIN_ASSOCIATION: </html:p>
12647 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
12648 <html:p>PROTEIN_CLASS: </html:p>
12649 </notes>
12650 <listOfReactants>
12651 <speciesReference species="M_nac_e" stoichiometry="1.000000"/>
12652 </listOfReactants>
12653 <listOfProducts>
12654 <speciesReference species="M_nac_c" stoichiometry="1.000000"/>
12655 </listOfProducts>
12656 </reaction>
12657 <reaction id="R_NADDP" name="R_NAD_diphosphatase" reversible="false">
12658 <notes>
12659 <html:p>GENE_ASSOCIATION: b2411</html:p>
12660 <html:p>PROTEIN_ASSOCIATION: Lig</html:p>
12661 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
12662 <html:p>PROTEIN_CLASS: 3.6.1.22</html:p>
12663 </notes>
12664 <listOfReactants>
12665 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
12666 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
12667 </listOfReactants>
12668 <listOfProducts>
12669 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
12670 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
12671 <speciesReference species="M_nmn_c" stoichiometry="1.000000"/>
12672 </listOfProducts>
12673 </reaction>
12674 <reaction id="R_NADDPe" name="R_NAD_diphosphatase__extracellular_" reversible="false">
12675 <notes>
12676 <html:p>GENE_ASSOCIATION: </html:p>
12677 <html:p>PROTEIN_ASSOCIATION: </html:p>
12678 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
12679 <html:p>PROTEIN_CLASS: 3.6.1.22</html:p>
12680 </notes>
12681 <listOfReactants>
12682 <speciesReference species="M_h2o_e" stoichiometry="1.000000"/>
12683 <speciesReference species="M_nad_e" stoichiometry="1.000000"/>
12684 </listOfReactants>
12685 <listOfProducts>
12686 <speciesReference species="M_amp_e" stoichiometry="1.000000"/>
12687 <speciesReference species="M_h_e" stoichiometry="2.000000"/>
12688 <speciesReference species="M_nmn_e" stoichiometry="1.000000"/>
12689 </listOfProducts>
12690 </reaction>
12691 <reaction id="R_NADH10" name="R_NADH_dehydrogenase__menaquinone_8__0_protons_" reversible="false">
12692 <notes>
12693 <html:p>GENE_ASSOCIATION: b1109</html:p>
12694 <html:p>PROTEIN_ASSOCIATION: Ndh</html:p>
12695 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
12696 <html:p>PROTEIN_CLASS: 1.6.5.3</html:p>
12697 </notes>
12698 <listOfReactants>
12699 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
12700 <speciesReference species="M_mqn8_c" stoichiometry="1.000000"/>
12701 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
12702 </listOfReactants>
12703 <listOfProducts>
12704 <speciesReference species="M_mql8_c" stoichiometry="1.000000"/>
12705 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
12706 </listOfProducts>
12707 </reaction>
12708 <reaction id="R_NADH5" name="R_NADH_dehydrogenase__ubiquinone_8__" reversible="false">
12709 <notes>
12710 <html:p>GENE_ASSOCIATION: b1109</html:p>
12711 <html:p>PROTEIN_ASSOCIATION: Ndh</html:p>
12712 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
12713 <html:p>PROTEIN_CLASS: 1.6.5.3</html:p>
12714 </notes>
12715 <listOfReactants>
12716 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
12717 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
12718 <speciesReference species="M_q8_c" stoichiometry="1.000000"/>
12719 </listOfReactants>
12720 <listOfProducts>
12721 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
12722 <speciesReference species="M_q8h2_c" stoichiometry="1.000000"/>
12723 </listOfProducts>
12724 </reaction>
12725 <reaction id="R_NADH6" name="R_NADH_dehydrogenase__ubiquinone_8__35_protons_" reversible="false">
12726 <notes>
12727 <html:p>GENE_ASSOCIATION: ( b2276 and b2277 and b2278 and b2279 and b2280 and b2281 and b2282 and b2283 and b2284 and b2285 and b2286 and b2287 and b2288 )</html:p>
12728 <html:p>PROTEIN_ASSOCIATION: Nuo</html:p>
12729 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
12730 <html:p>PROTEIN_CLASS: 1.6.5.3</html:p>
12731 </notes>
12732 <listOfReactants>
12733 <speciesReference species="M_h_c" stoichiometry="4.500000"/>
12734 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
12735 <speciesReference species="M_q8_c" stoichiometry="1.000000"/>
12736 </listOfReactants>
12737 <listOfProducts>
12738 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
12739 <speciesReference species="M_q8h2_c" stoichiometry="1.000000"/>
12740 <speciesReference species="M_h_e" stoichiometry="3.500000"/>
12741 </listOfProducts>
12742 </reaction>
12743 <reaction id="R_NADH7" name="R_NADH_dehydrogenase__menaquinone_8__2_protons_" reversible="false">
12744 <notes>
12745 <html:p>GENE_ASSOCIATION: ( b2276 and b2277 and b2278 and b2279 and b2280 and b2281 and b2282 and b2283 and b2284 and b2285 and b2286 and b2287 and b2288 )</html:p>
12746 <html:p>PROTEIN_ASSOCIATION: Nuo</html:p>
12747 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
12748 <html:p>PROTEIN_CLASS: 1.6.5.3</html:p>
12749 </notes>
12750 <listOfReactants>
12751 <speciesReference species="M_h_c" stoichiometry="3.000000"/>
12752 <speciesReference species="M_mqn8_c" stoichiometry="1.000000"/>
12753 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
12754 </listOfReactants>
12755 <listOfProducts>
12756 <speciesReference species="M_mql8_c" stoichiometry="1.000000"/>
12757 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
12758 <speciesReference species="M_h_e" stoichiometry="2.000000"/>
12759 </listOfProducts>
12760 </reaction>
12761 <reaction id="R_NADH8" name="R_NADH_dehydrogenase__demethylmenaquinone_8__28_protons_" reversible="false">
12762 <notes>
12763 <html:p>GENE_ASSOCIATION: ( b2276 and b2277 and b2278 and b2279 and b2280 and b2281 and b2282 and b2283 and b2284 and b2285 and b2286 and b2287 and b2288 )</html:p>
12764 <html:p>PROTEIN_ASSOCIATION: Nuo</html:p>
12765 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
12766 <html:p>PROTEIN_CLASS: 1.6.5.3</html:p>
12767 </notes>
12768 <listOfReactants>
12769 <speciesReference species="M_2dmmq8_c" stoichiometry="1.000000"/>
12770 <speciesReference species="M_h_c" stoichiometry="3.800000"/>
12771 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
12772 </listOfReactants>
12773 <listOfProducts>
12774 <speciesReference species="M_2dmmql8_c" stoichiometry="1.000000"/>
12775 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
12776 <speciesReference species="M_h_e" stoichiometry="2.800000"/>
12777 </listOfProducts>
12778 </reaction>
12779 <reaction id="R_NADH9" name="R_NADH_dehydrogenase__demethylmenaquinone_8__0_protons_" reversible="false">
12780 <notes>
12781 <html:p>GENE_ASSOCIATION: b1109</html:p>
12782 <html:p>PROTEIN_ASSOCIATION: Ndh</html:p>
12783 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
12784 <html:p>PROTEIN_CLASS: 1.6.5.3</html:p>
12785 </notes>
12786 <listOfReactants>
12787 <speciesReference species="M_2dmmq8_c" stoichiometry="1.000000"/>
12788 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
12789 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
12790 </listOfReactants>
12791 <listOfProducts>
12792 <speciesReference species="M_2dmmql8_c" stoichiometry="1.000000"/>
12793 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
12794 </listOfProducts>
12795 </reaction>
12796 <reaction id="R_NADK" name="R_NAD_kinase" reversible="false">
12797 <notes>
12798 <html:p>GENE_ASSOCIATION: b2615</html:p>
12799 <html:p>PROTEIN_ASSOCIATION: YfjB</html:p>
12800 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
12801 <html:p>PROTEIN_CLASS: 2.7.1.23</html:p>
12802 </notes>
12803 <listOfReactants>
12804 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
12805 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
12806 </listOfReactants>
12807 <listOfProducts>
12808 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
12809 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
12810 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
12811 </listOfProducts>
12812 </reaction>
12813 <reaction id="R_NADPPPS" name="R_NADP_phosphatase" reversible="false">
12814 <notes>
12815 <html:p>GENE_ASSOCIATION: </html:p>
12816 <html:p>PROTEIN_ASSOCIATION: </html:p>
12817 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
12818 <html:p>PROTEIN_CLASS: </html:p>
12819 </notes>
12820 <listOfReactants>
12821 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
12822 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
12823 </listOfReactants>
12824 <listOfProducts>
12825 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
12826 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
12827 </listOfProducts>
12828 </reaction>
12829 <reaction id="R_NADS1" name="R_NAD_synthase__nh3_" reversible="false">
12830 <notes>
12831 <html:p>GENE_ASSOCIATION: b1740</html:p>
12832 <html:p>PROTEIN_ASSOCIATION: NadEec</html:p>
12833 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
12834 <html:p>PROTEIN_CLASS: 6.3.1.5</html:p>
12835 </notes>
12836 <listOfReactants>
12837 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
12838 <speciesReference species="M_dnad_c" stoichiometry="1.000000"/>
12839 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
12840 </listOfReactants>
12841 <listOfProducts>
12842 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
12843 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
12844 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
12845 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
12846 </listOfProducts>
12847 </reaction>
12848 <reaction id="R_NADTRHD" name="R_NAD_transhydrogenase" reversible="false">
12849 <notes>
12850 <html:p>GENE_ASSOCIATION: ( ( b1602 and b1603 ) or b3962 )</html:p>
12851 <html:p>PROTEIN_ASSOCIATION: ( Pnt ) or ( SthA )</html:p>
12852 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
12853 <html:p>PROTEIN_CLASS: </html:p>
12854 </notes>
12855 <listOfReactants>
12856 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
12857 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
12858 </listOfReactants>
12859 <listOfProducts>
12860 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
12861 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
12862 </listOfProducts>
12863 </reaction>
12864 <reaction id="R_NAMNPP" name="R_nicotinic_acid_mononucleotide_pyrophosphorylase" reversible="false">
12865 <notes>
12866 <html:p>GENE_ASSOCIATION: b0931</html:p>
12867 <html:p>PROTEIN_ASSOCIATION: PncB</html:p>
12868 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
12869 <html:p>PROTEIN_CLASS: 2.4.2.11</html:p>
12870 </notes>
12871 <listOfReactants>
12872 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
12873 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
12874 <speciesReference species="M_nac_c" stoichiometry="1.000000"/>
12875 <speciesReference species="M_prpp_c" stoichiometry="1.000000"/>
12876 </listOfReactants>
12877 <listOfProducts>
12878 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
12879 <speciesReference species="M_nicrnt_c" stoichiometry="1.000000"/>
12880 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
12881 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
12882 </listOfProducts>
12883 </reaction>
12884 <reaction id="R_NAt3_1" name="R_sodium_proton_antiporter__HNA_is_11_" reversible="true">
12885 <notes>
12886 <html:p>GENE_ASSOCIATION: b1216</html:p>
12887 <html:p>PROTEIN_ASSOCIATION: ChaA</html:p>
12888 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
12889 <html:p>PROTEIN_CLASS: </html:p>
12890 </notes>
12891 <listOfReactants>
12892 <speciesReference species="M_na1_c" stoichiometry="1.000000"/>
12893 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
12894 </listOfReactants>
12895 <listOfProducts>
12896 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
12897 <speciesReference species="M_na1_e" stoichiometry="1.000000"/>
12898 </listOfProducts>
12899 </reaction>
12900 <reaction id="R_NAt3_15" name="R_sodium_proton_antiporter__HNA_is_15_" reversible="false">
12901 <notes>
12902 <html:p>GENE_ASSOCIATION: b1186</html:p>
12903 <html:p>PROTEIN_ASSOCIATION: NhaB</html:p>
12904 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
12905 <html:p>PROTEIN_CLASS: </html:p>
12906 </notes>
12907 <listOfReactants>
12908 <speciesReference species="M_na1_c" stoichiometry="2.000000"/>
12909 <speciesReference species="M_h_e" stoichiometry="3.000000"/>
12910 </listOfReactants>
12911 <listOfProducts>
12912 <speciesReference species="M_h_c" stoichiometry="3.000000"/>
12913 <speciesReference species="M_na1_e" stoichiometry="2.000000"/>
12914 </listOfProducts>
12915 </reaction>
12916 <reaction id="R_NAt3_2" name="R_sodium_proton_antiporter__HNA_is_2_" reversible="false">
12917 <notes>
12918 <html:p>GENE_ASSOCIATION: b0019</html:p>
12919 <html:p>PROTEIN_ASSOCIATION: NhaA</html:p>
12920 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
12921 <html:p>PROTEIN_CLASS: </html:p>
12922 </notes>
12923 <listOfReactants>
12924 <speciesReference species="M_na1_c" stoichiometry="1.000000"/>
12925 <speciesReference species="M_h_e" stoichiometry="2.000000"/>
12926 </listOfReactants>
12927 <listOfProducts>
12928 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
12929 <speciesReference species="M_na1_e" stoichiometry="1.000000"/>
12930 </listOfProducts>
12931 </reaction>
12932 <reaction id="R_NDPK1" name="R_nucleoside_diphosphate_kinase__ATPGDP_" reversible="true">
12933 <notes>
12934 <html:p>GENE_ASSOCIATION: b2518</html:p>
12935 <html:p>PROTEIN_ASSOCIATION: Ndk</html:p>
12936 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
12937 <html:p>PROTEIN_CLASS: 2.7.4.6</html:p>
12938 </notes>
12939 <listOfReactants>
12940 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
12941 <speciesReference species="M_gdp_c" stoichiometry="1.000000"/>
12942 </listOfReactants>
12943 <listOfProducts>
12944 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
12945 <speciesReference species="M_gtp_c" stoichiometry="1.000000"/>
12946 </listOfProducts>
12947 </reaction>
12948 <reaction id="R_NDPK2" name="R_nucleoside_diphosphate_kinase__ATPUDP_" reversible="true">
12949 <notes>
12950 <html:p>GENE_ASSOCIATION: b2518</html:p>
12951 <html:p>PROTEIN_ASSOCIATION: Ndk</html:p>
12952 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
12953 <html:p>PROTEIN_CLASS: 2.7.4.6</html:p>
12954 </notes>
12955 <listOfReactants>
12956 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
12957 <speciesReference species="M_udp_c" stoichiometry="1.000000"/>
12958 </listOfReactants>
12959 <listOfProducts>
12960 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
12961 <speciesReference species="M_utp_c" stoichiometry="1.000000"/>
12962 </listOfProducts>
12963 </reaction>
12964 <reaction id="R_NDPK3" name="R_nucleoside_diphosphate_kinase__ATPCDP_" reversible="true">
12965 <notes>
12966 <html:p>GENE_ASSOCIATION: b2518</html:p>
12967 <html:p>PROTEIN_ASSOCIATION: Ndk</html:p>
12968 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
12969 <html:p>PROTEIN_CLASS: 2.7.4.6</html:p>
12970 </notes>
12971 <listOfReactants>
12972 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
12973 <speciesReference species="M_cdp_c" stoichiometry="1.000000"/>
12974 </listOfReactants>
12975 <listOfProducts>
12976 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
12977 <speciesReference species="M_ctp_c" stoichiometry="1.000000"/>
12978 </listOfProducts>
12979 </reaction>
12980 <reaction id="R_NDPK4" name="R_nucleoside_diphosphate_kinase__ATPdTDP_" reversible="true">
12981 <notes>
12982 <html:p>GENE_ASSOCIATION: b2518</html:p>
12983 <html:p>PROTEIN_ASSOCIATION: Ndk</html:p>
12984 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
12985 <html:p>PROTEIN_CLASS: 2.7.4.6</html:p>
12986 </notes>
12987 <listOfReactants>
12988 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
12989 <speciesReference species="M_dtdp_c" stoichiometry="1.000000"/>
12990 </listOfReactants>
12991 <listOfProducts>
12992 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
12993 <speciesReference species="M_dttp_c" stoichiometry="1.000000"/>
12994 </listOfProducts>
12995 </reaction>
12996 <reaction id="R_NDPK5" name="R_nucleoside_diphosphate_kinase__ATPdGDP_" reversible="true">
12997 <notes>
12998 <html:p>GENE_ASSOCIATION: b2518</html:p>
12999 <html:p>PROTEIN_ASSOCIATION: Ndk</html:p>
13000 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13001 <html:p>PROTEIN_CLASS: 2.7.4.6</html:p>
13002 </notes>
13003 <listOfReactants>
13004 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
13005 <speciesReference species="M_dgdp_c" stoichiometry="1.000000"/>
13006 </listOfReactants>
13007 <listOfProducts>
13008 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
13009 <speciesReference species="M_dgtp_c" stoichiometry="1.000000"/>
13010 </listOfProducts>
13011 </reaction>
13012 <reaction id="R_NDPK6" name="R_nucleoside_diphosphate_kinase__ATPdUDP_" reversible="true">
13013 <notes>
13014 <html:p>GENE_ASSOCIATION: b2518</html:p>
13015 <html:p>PROTEIN_ASSOCIATION: Ndk</html:p>
13016 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13017 <html:p>PROTEIN_CLASS: 2.7.4.6</html:p>
13018 </notes>
13019 <listOfReactants>
13020 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
13021 <speciesReference species="M_dudp_c" stoichiometry="1.000000"/>
13022 </listOfReactants>
13023 <listOfProducts>
13024 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
13025 <speciesReference species="M_dutp_c" stoichiometry="1.000000"/>
13026 </listOfProducts>
13027 </reaction>
13028 <reaction id="R_NDPK7" name="R_nucleoside_diphosphate_kinase__ATPdCDP_" reversible="true">
13029 <notes>
13030 <html:p>GENE_ASSOCIATION: b2518</html:p>
13031 <html:p>PROTEIN_ASSOCIATION: Ndk</html:p>
13032 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13033 <html:p>PROTEIN_CLASS: 2.7.4.6</html:p>
13034 </notes>
13035 <listOfReactants>
13036 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
13037 <speciesReference species="M_dcdp_c" stoichiometry="1.000000"/>
13038 </listOfReactants>
13039 <listOfProducts>
13040 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
13041 <speciesReference species="M_dctp_c" stoichiometry="1.000000"/>
13042 </listOfProducts>
13043 </reaction>
13044 <reaction id="R_NDPK8" name="R_nucleoside_diphosphate_kinase__ATPdADP_" reversible="true">
13045 <notes>
13046 <html:p>GENE_ASSOCIATION: b2518</html:p>
13047 <html:p>PROTEIN_ASSOCIATION: Ndk</html:p>
13048 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13049 <html:p>PROTEIN_CLASS: 2.7.4.6</html:p>
13050 </notes>
13051 <listOfReactants>
13052 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
13053 <speciesReference species="M_dadp_c" stoichiometry="1.000000"/>
13054 </listOfReactants>
13055 <listOfProducts>
13056 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
13057 <speciesReference species="M_datp_c" stoichiometry="1.000000"/>
13058 </listOfProducts>
13059 </reaction>
13060 <reaction id="R_NH4t" name="R_ammonia_reversible_transport" reversible="true">
13061 <notes>
13062 <html:p>GENE_ASSOCIATION: b0451</html:p>
13063 <html:p>PROTEIN_ASSOCIATION: AmtB</html:p>
13064 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
13065 <html:p>PROTEIN_CLASS: </html:p>
13066 </notes>
13067 <listOfReactants>
13068 <speciesReference species="M_nh4_e" stoichiometry="1.000000"/>
13069 </listOfReactants>
13070 <listOfProducts>
13071 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
13072 </listOfProducts>
13073 </reaction>
13074 <reaction id="R_NMNAT" name="R_nicotinamide_nucleotide_adenylyltransferase" reversible="false">
13075 <notes>
13076 <html:p>GENE_ASSOCIATION: b0639</html:p>
13077 <html:p>PROTEIN_ASSOCIATION: NadD</html:p>
13078 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
13079 <html:p>PROTEIN_CLASS: 2.7.7.1</html:p>
13080 </notes>
13081 <listOfReactants>
13082 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
13083 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
13084 <speciesReference species="M_nmn_c" stoichiometry="1.000000"/>
13085 </listOfReactants>
13086 <listOfProducts>
13087 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
13088 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
13089 </listOfProducts>
13090 </reaction>
13091 <reaction id="R_NMNDA" name="R_nicotinamide_nucleotide_amidase" reversible="false">
13092 <notes>
13093 <html:p>GENE_ASSOCIATION: </html:p>
13094 <html:p>PROTEIN_ASSOCIATION: </html:p>
13095 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
13096 <html:p>PROTEIN_CLASS: 3.5.1.42</html:p>
13097 </notes>
13098 <listOfReactants>
13099 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13100 <speciesReference species="M_nmn_c" stoichiometry="1.000000"/>
13101 </listOfReactants>
13102 <listOfProducts>
13103 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
13104 <speciesReference species="M_nicrnt_c" stoichiometry="1.000000"/>
13105 </listOfProducts>
13106 </reaction>
13107 <reaction id="R_NMNN" name="R_NMN_nucleosidase" reversible="false">
13108 <notes>
13109 <html:p>GENE_ASSOCIATION: </html:p>
13110 <html:p>PROTEIN_ASSOCIATION: </html:p>
13111 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
13112 <html:p>PROTEIN_CLASS: 3.2.2.14</html:p>
13113 </notes>
13114 <listOfReactants>
13115 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13116 <speciesReference species="M_nmn_c" stoichiometry="1.000000"/>
13117 </listOfReactants>
13118 <listOfProducts>
13119 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
13120 <speciesReference species="M_ncam_c" stoichiometry="1.000000"/>
13121 <speciesReference species="M_r5p_c" stoichiometry="1.000000"/>
13122 </listOfProducts>
13123 </reaction>
13124 <reaction id="R_NMNP" name="R_NMN_permease" reversible="false">
13125 <notes>
13126 <html:p>GENE_ASSOCIATION: b0751</html:p>
13127 <html:p>PROTEIN_ASSOCIATION: PnuCec</html:p>
13128 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
13129 <html:p>PROTEIN_CLASS: </html:p>
13130 </notes>
13131 <listOfReactants>
13132 <speciesReference species="M_nmn_e" stoichiometry="1.000000"/>
13133 </listOfReactants>
13134 <listOfProducts>
13135 <speciesReference species="M_nmn_c" stoichiometry="1.000000"/>
13136 </listOfProducts>
13137 </reaction>
13138 <reaction id="R_NMNt7" name="R_NMN_transport_via_NMN_glycohydrolase" reversible="false">
13139 <notes>
13140 <html:p>GENE_ASSOCIATION: </html:p>
13141 <html:p>PROTEIN_ASSOCIATION: </html:p>
13142 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
13143 <html:p>PROTEIN_CLASS: 3.2.2.14</html:p>
13144 </notes>
13145 <listOfReactants>
13146 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13147 <speciesReference species="M_nmn_e" stoichiometry="1.000000"/>
13148 </listOfReactants>
13149 <listOfProducts>
13150 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
13151 <speciesReference species="M_ncam_c" stoichiometry="1.000000"/>
13152 <speciesReference species="M_r5p_c" stoichiometry="1.000000"/>
13153 </listOfProducts>
13154 </reaction>
13155 <reaction id="R_NNAM" name="R_nicotinamidase" reversible="false">
13156 <notes>
13157 <html:p>GENE_ASSOCIATION: b1768</html:p>
13158 <html:p>PROTEIN_ASSOCIATION: PncA</html:p>
13159 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
13160 <html:p>PROTEIN_CLASS: 3.5.1.19</html:p>
13161 </notes>
13162 <listOfReactants>
13163 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13164 <speciesReference species="M_ncam_c" stoichiometry="1.000000"/>
13165 </listOfReactants>
13166 <listOfProducts>
13167 <speciesReference species="M_nac_c" stoichiometry="1.000000"/>
13168 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
13169 </listOfProducts>
13170 </reaction>
13171 <reaction id="R_NNAT" name="R_nicotinate_nucleotide_adenylyltransferase" reversible="false">
13172 <notes>
13173 <html:p>GENE_ASSOCIATION: b0639</html:p>
13174 <html:p>PROTEIN_ASSOCIATION: NadD</html:p>
13175 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
13176 <html:p>PROTEIN_CLASS: 2.7.7.18</html:p>
13177 </notes>
13178 <listOfReactants>
13179 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
13180 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
13181 <speciesReference species="M_nicrnt_c" stoichiometry="1.000000"/>
13182 </listOfReactants>
13183 <listOfProducts>
13184 <speciesReference species="M_dnad_c" stoichiometry="1.000000"/>
13185 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
13186 </listOfProducts>
13187 </reaction>
13188 <reaction id="R_NNDMBRT" name="R_Nicotinate_nucleotide_dimethylbenzimidazole_phosphoribosyltransferase" reversible="false">
13189 <notes>
13190 <html:p>GENE_ASSOCIATION: b1991</html:p>
13191 <html:p>PROTEIN_ASSOCIATION: CobT</html:p>
13192 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
13193 <html:p>PROTEIN_CLASS: </html:p>
13194 </notes>
13195 <listOfReactants>
13196 <speciesReference species="M_dmbzid_c" stoichiometry="1.000000"/>
13197 <speciesReference species="M_nicrnt_c" stoichiometry="1.000000"/>
13198 </listOfReactants>
13199 <listOfProducts>
13200 <speciesReference species="M_5prdmbz_c" stoichiometry="1.000000"/>
13201 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
13202 <speciesReference species="M_nac_c" stoichiometry="1.000000"/>
13203 </listOfProducts>
13204 </reaction>
13205 <reaction id="R_NNDPR" name="R_nicotinate_nucleotide_diphosphorylase__carboxylating_" reversible="false">
13206 <notes>
13207 <html:p>GENE_ASSOCIATION: b0109</html:p>
13208 <html:p>PROTEIN_ASSOCIATION: NadCec</html:p>
13209 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
13210 <html:p>PROTEIN_CLASS: 2.4.2.19</html:p>
13211 </notes>
13212 <listOfReactants>
13213 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
13214 <speciesReference species="M_prpp_c" stoichiometry="1.000000"/>
13215 <speciesReference species="M_quln_c" stoichiometry="1.000000"/>
13216 </listOfReactants>
13217 <listOfProducts>
13218 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
13219 <speciesReference species="M_nicrnt_c" stoichiometry="1.000000"/>
13220 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
13221 </listOfProducts>
13222 </reaction>
13223 <reaction id="R_NO2t2r" name="R_nitrite_transport_in_via_proton_symport__reversible" reversible="true">
13224 <notes>
13225 <html:p>GENE_ASSOCIATION: ( b1223 or b3367 )</html:p>
13226 <html:p>PROTEIN_ASSOCIATION: ( NarKec ) or ( NirC )</html:p>
13227 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
13228 <html:p>PROTEIN_CLASS: </html:p>
13229 </notes>
13230 <listOfReactants>
13231 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
13232 <speciesReference species="M_no2_e" stoichiometry="1.000000"/>
13233 </listOfReactants>
13234 <listOfProducts>
13235 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
13236 <speciesReference species="M_no2_c" stoichiometry="1.000000"/>
13237 </listOfProducts>
13238 </reaction>
13239 <reaction id="R_NO3R1" name="R_Nitrate_reductase__Ubiquinol_8_" reversible="false">
13240 <notes>
13241 <html:p>GENE_ASSOCIATION: ( b1224 and b1225 and b1226 and b1227 )</html:p>
13242 <html:p>PROTEIN_ASSOCIATION: NarGHIJ</html:p>
13243 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
13244 <html:p>PROTEIN_CLASS: 1.7.99.4</html:p>
13245 </notes>
13246 <listOfReactants>
13247 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
13248 <speciesReference species="M_no3_c" stoichiometry="1.000000"/>
13249 <speciesReference species="M_q8h2_c" stoichiometry="1.000000"/>
13250 </listOfReactants>
13251 <listOfProducts>
13252 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13253 <speciesReference species="M_no2_c" stoichiometry="1.000000"/>
13254 <speciesReference species="M_q8_c" stoichiometry="1.000000"/>
13255 <speciesReference species="M_h_e" stoichiometry="2.000000"/>
13256 </listOfProducts>
13257 </reaction>
13258 <reaction id="R_NO3R2" name="R_Nitrate_reductase__Menaquinol_8_" reversible="false">
13259 <notes>
13260 <html:p>GENE_ASSOCIATION: ( b1224 and b1225 and b1226 and b1227 )</html:p>
13261 <html:p>PROTEIN_ASSOCIATION: NarGHIJ</html:p>
13262 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
13263 <html:p>PROTEIN_CLASS: </html:p>
13264 </notes>
13265 <listOfReactants>
13266 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
13267 <speciesReference species="M_mql8_c" stoichiometry="1.000000"/>
13268 <speciesReference species="M_no3_c" stoichiometry="1.000000"/>
13269 </listOfReactants>
13270 <listOfProducts>
13271 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13272 <speciesReference species="M_mqn8_c" stoichiometry="1.000000"/>
13273 <speciesReference species="M_no2_c" stoichiometry="1.000000"/>
13274 <speciesReference species="M_h_e" stoichiometry="2.000000"/>
13275 </listOfProducts>
13276 </reaction>
13277 <reaction id="R_NO3t7" name="R_nitrate_transport_in_via_nitrite_antiport" reversible="false">
13278 <notes>
13279 <html:p>GENE_ASSOCIATION: ( b1223 or b1469 )</html:p>
13280 <html:p>PROTEIN_ASSOCIATION: ( NarKec ) or ( NarU )</html:p>
13281 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
13282 <html:p>PROTEIN_CLASS: </html:p>
13283 </notes>
13284 <listOfReactants>
13285 <speciesReference species="M_no2_c" stoichiometry="1.000000"/>
13286 <speciesReference species="M_no3_e" stoichiometry="1.000000"/>
13287 </listOfReactants>
13288 <listOfProducts>
13289 <speciesReference species="M_no3_c" stoichiometry="1.000000"/>
13290 <speciesReference species="M_no2_e" stoichiometry="1.000000"/>
13291 </listOfProducts>
13292 </reaction>
13293 <reaction id="R_NPHS" name="R_naphthoate_synthase" reversible="false">
13294 <notes>
13295 <html:p>GENE_ASSOCIATION: b2262</html:p>
13296 <html:p>PROTEIN_ASSOCIATION: MenB</html:p>
13297 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
13298 <html:p>PROTEIN_CLASS: 4.1.3.36</html:p>
13299 </notes>
13300 <listOfReactants>
13301 <speciesReference species="M_sbzcoa_c" stoichiometry="1.000000"/>
13302 </listOfReactants>
13303 <listOfProducts>
13304 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
13305 <speciesReference species="M_dhna_c" stoichiometry="1.000000"/>
13306 </listOfProducts>
13307 </reaction>
13308 <reaction id="R_NTD1" name="R_5__nucleotidase__dUMP_" reversible="false">
13309 <notes>
13310 <html:p>GENE_ASSOCIATION: b0480</html:p>
13311 <html:p>PROTEIN_ASSOCIATION: UshA</html:p>
13312 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13313 <html:p>PROTEIN_CLASS: 3.1.3.5</html:p>
13314 </notes>
13315 <listOfReactants>
13316 <speciesReference species="M_dump_c" stoichiometry="1.000000"/>
13317 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13318 </listOfReactants>
13319 <listOfProducts>
13320 <speciesReference species="M_duri_c" stoichiometry="1.000000"/>
13321 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
13322 </listOfProducts>
13323 </reaction>
13324 <reaction id="R_NTD10" name="R_5__nucleotidase__XMP_" reversible="false">
13325 <notes>
13326 <html:p>GENE_ASSOCIATION: b0480</html:p>
13327 <html:p>PROTEIN_ASSOCIATION: UshA</html:p>
13328 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13329 <html:p>PROTEIN_CLASS: 3.1.3.5</html:p>
13330 </notes>
13331 <listOfReactants>
13332 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13333 <speciesReference species="M_xmp_c" stoichiometry="1.000000"/>
13334 </listOfReactants>
13335 <listOfProducts>
13336 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
13337 <speciesReference species="M_xtsn_c" stoichiometry="1.000000"/>
13338 </listOfProducts>
13339 </reaction>
13340 <reaction id="R_NTD11" name="R_5__nucleotidase__IMP_" reversible="false">
13341 <notes>
13342 <html:p>GENE_ASSOCIATION: b0480</html:p>
13343 <html:p>PROTEIN_ASSOCIATION: UshA</html:p>
13344 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13345 <html:p>PROTEIN_CLASS: 3.1.3.5</html:p>
13346 </notes>
13347 <listOfReactants>
13348 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13349 <speciesReference species="M_imp_c" stoichiometry="1.000000"/>
13350 </listOfReactants>
13351 <listOfProducts>
13352 <speciesReference species="M_ins_c" stoichiometry="1.000000"/>
13353 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
13354 </listOfProducts>
13355 </reaction>
13356 <reaction id="R_NTD2" name="R_5__nucleotidase__UMP_" reversible="false">
13357 <notes>
13358 <html:p>GENE_ASSOCIATION: b0480</html:p>
13359 <html:p>PROTEIN_ASSOCIATION: UshA</html:p>
13360 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13361 <html:p>PROTEIN_CLASS: 3.1.3.5</html:p>
13362 </notes>
13363 <listOfReactants>
13364 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13365 <speciesReference species="M_ump_c" stoichiometry="1.000000"/>
13366 </listOfReactants>
13367 <listOfProducts>
13368 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
13369 <speciesReference species="M_uri_c" stoichiometry="1.000000"/>
13370 </listOfProducts>
13371 </reaction>
13372 <reaction id="R_NTD3" name="R_5__nucleotidase__dCMP_" reversible="false">
13373 <notes>
13374 <html:p>GENE_ASSOCIATION: b0480</html:p>
13375 <html:p>PROTEIN_ASSOCIATION: UshA</html:p>
13376 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13377 <html:p>PROTEIN_CLASS: 3.1.3.5</html:p>
13378 </notes>
13379 <listOfReactants>
13380 <speciesReference species="M_dcmp_c" stoichiometry="1.000000"/>
13381 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13382 </listOfReactants>
13383 <listOfProducts>
13384 <speciesReference species="M_dcyt_c" stoichiometry="1.000000"/>
13385 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
13386 </listOfProducts>
13387 </reaction>
13388 <reaction id="R_NTD4" name="R_5__nucleotidase__CMP_" reversible="false">
13389 <notes>
13390 <html:p>GENE_ASSOCIATION: b0480</html:p>
13391 <html:p>PROTEIN_ASSOCIATION: UshA</html:p>
13392 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13393 <html:p>PROTEIN_CLASS: 3.1.3.5</html:p>
13394 </notes>
13395 <listOfReactants>
13396 <speciesReference species="M_cmp_c" stoichiometry="1.000000"/>
13397 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13398 </listOfReactants>
13399 <listOfProducts>
13400 <speciesReference species="M_cytd_c" stoichiometry="1.000000"/>
13401 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
13402 </listOfProducts>
13403 </reaction>
13404 <reaction id="R_NTD5" name="R_5__nucleotidase__dTMP_" reversible="false">
13405 <notes>
13406 <html:p>GENE_ASSOCIATION: b0480</html:p>
13407 <html:p>PROTEIN_ASSOCIATION: UshA</html:p>
13408 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13409 <html:p>PROTEIN_CLASS: 3.1.3.5</html:p>
13410 </notes>
13411 <listOfReactants>
13412 <speciesReference species="M_dtmp_c" stoichiometry="1.000000"/>
13413 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13414 </listOfReactants>
13415 <listOfProducts>
13416 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
13417 <speciesReference species="M_thymd_c" stoichiometry="1.000000"/>
13418 </listOfProducts>
13419 </reaction>
13420 <reaction id="R_NTD6" name="R_5__nucleotidase__dAMP_" reversible="false">
13421 <notes>
13422 <html:p>GENE_ASSOCIATION: b0480</html:p>
13423 <html:p>PROTEIN_ASSOCIATION: UshA</html:p>
13424 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13425 <html:p>PROTEIN_CLASS: 3.1.3.5</html:p>
13426 </notes>
13427 <listOfReactants>
13428 <speciesReference species="M_damp_c" stoichiometry="1.000000"/>
13429 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13430 </listOfReactants>
13431 <listOfProducts>
13432 <speciesReference species="M_dad_2_c" stoichiometry="1.000000"/>
13433 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
13434 </listOfProducts>
13435 </reaction>
13436 <reaction id="R_NTD7" name="R_5__nucleotidase__AMP_" reversible="false">
13437 <notes>
13438 <html:p>GENE_ASSOCIATION: b0480</html:p>
13439 <html:p>PROTEIN_ASSOCIATION: UshA</html:p>
13440 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13441 <html:p>PROTEIN_CLASS: 3.1.3.5</html:p>
13442 </notes>
13443 <listOfReactants>
13444 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
13445 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13446 </listOfReactants>
13447 <listOfProducts>
13448 <speciesReference species="M_adn_c" stoichiometry="1.000000"/>
13449 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
13450 </listOfProducts>
13451 </reaction>
13452 <reaction id="R_NTD8" name="R_5__nucleotidase__dGMP_" reversible="false">
13453 <notes>
13454 <html:p>GENE_ASSOCIATION: b0480</html:p>
13455 <html:p>PROTEIN_ASSOCIATION: UshA</html:p>
13456 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13457 <html:p>PROTEIN_CLASS: 3.1.3.5</html:p>
13458 </notes>
13459 <listOfReactants>
13460 <speciesReference species="M_dgmp_c" stoichiometry="1.000000"/>
13461 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13462 </listOfReactants>
13463 <listOfProducts>
13464 <speciesReference species="M_dgsn_c" stoichiometry="1.000000"/>
13465 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
13466 </listOfProducts>
13467 </reaction>
13468 <reaction id="R_NTD9" name="R_5__nucleotidase__GMP_" reversible="false">
13469 <notes>
13470 <html:p>GENE_ASSOCIATION: b0480</html:p>
13471 <html:p>PROTEIN_ASSOCIATION: UshA</html:p>
13472 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13473 <html:p>PROTEIN_CLASS: 3.1.3.5</html:p>
13474 </notes>
13475 <listOfReactants>
13476 <speciesReference species="M_gmp_c" stoichiometry="1.000000"/>
13477 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13478 </listOfReactants>
13479 <listOfProducts>
13480 <speciesReference species="M_gsn_c" stoichiometry="1.000000"/>
13481 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
13482 </listOfProducts>
13483 </reaction>
13484 <reaction id="R_NTPP1" name="R_Nucleoside_triphosphate_pyrophosphorylase__dgtp_" reversible="false">
13485 <notes>
13486 <html:p>GENE_ASSOCIATION: ( b0099 or b2781 )</html:p>
13487 <html:p>PROTEIN_ASSOCIATION: ( MutT ) or ( MazG )</html:p>
13488 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13489 <html:p>PROTEIN_CLASS: </html:p>
13490 </notes>
13491 <listOfReactants>
13492 <speciesReference species="M_dgtp_c" stoichiometry="1.000000"/>
13493 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13494 </listOfReactants>
13495 <listOfProducts>
13496 <speciesReference species="M_dgmp_c" stoichiometry="1.000000"/>
13497 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
13498 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
13499 </listOfProducts>
13500 </reaction>
13501 <reaction id="R_NTPP2" name="R_Nucleoside_triphosphate_pyrophosphorylase__gtp_" reversible="false">
13502 <notes>
13503 <html:p>GENE_ASSOCIATION: ( b0099 or b2781 )</html:p>
13504 <html:p>PROTEIN_ASSOCIATION: ( MutT ) or ( MazG )</html:p>
13505 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13506 <html:p>PROTEIN_CLASS: </html:p>
13507 </notes>
13508 <listOfReactants>
13509 <speciesReference species="M_gtp_c" stoichiometry="1.000000"/>
13510 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13511 </listOfReactants>
13512 <listOfProducts>
13513 <speciesReference species="M_gmp_c" stoichiometry="1.000000"/>
13514 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
13515 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
13516 </listOfProducts>
13517 </reaction>
13518 <reaction id="R_NTPP3" name="R_Nucleoside_triphosphate_pyrophosphorylase__dctp_" reversible="false">
13519 <notes>
13520 <html:p>GENE_ASSOCIATION: b2781</html:p>
13521 <html:p>PROTEIN_ASSOCIATION: MazG</html:p>
13522 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13523 <html:p>PROTEIN_CLASS: </html:p>
13524 </notes>
13525 <listOfReactants>
13526 <speciesReference species="M_dctp_c" stoichiometry="1.000000"/>
13527 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13528 </listOfReactants>
13529 <listOfProducts>
13530 <speciesReference species="M_dcmp_c" stoichiometry="1.000000"/>
13531 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
13532 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
13533 </listOfProducts>
13534 </reaction>
13535 <reaction id="R_NTPP4" name="R_Nucleoside_triphosphate_pyrophosphorylase__ctp_" reversible="false">
13536 <notes>
13537 <html:p>GENE_ASSOCIATION: b2781</html:p>
13538 <html:p>PROTEIN_ASSOCIATION: MazG</html:p>
13539 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13540 <html:p>PROTEIN_CLASS: </html:p>
13541 </notes>
13542 <listOfReactants>
13543 <speciesReference species="M_ctp_c" stoichiometry="1.000000"/>
13544 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13545 </listOfReactants>
13546 <listOfProducts>
13547 <speciesReference species="M_cmp_c" stoichiometry="1.000000"/>
13548 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
13549 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
13550 </listOfProducts>
13551 </reaction>
13552 <reaction id="R_NTPP5" name="R_Nucleoside_triphosphate_pyrophosphorylase__datp_" reversible="false">
13553 <notes>
13554 <html:p>GENE_ASSOCIATION: b2781</html:p>
13555 <html:p>PROTEIN_ASSOCIATION: MazG</html:p>
13556 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13557 <html:p>PROTEIN_CLASS: </html:p>
13558 </notes>
13559 <listOfReactants>
13560 <speciesReference species="M_datp_c" stoichiometry="1.000000"/>
13561 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13562 </listOfReactants>
13563 <listOfProducts>
13564 <speciesReference species="M_damp_c" stoichiometry="1.000000"/>
13565 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
13566 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
13567 </listOfProducts>
13568 </reaction>
13569 <reaction id="R_NTPP6" name="R_Nucleoside_triphosphate_pyrophosphorylase__atp_" reversible="false">
13570 <notes>
13571 <html:p>GENE_ASSOCIATION: b2781</html:p>
13572 <html:p>PROTEIN_ASSOCIATION: MazG</html:p>
13573 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13574 <html:p>PROTEIN_CLASS: </html:p>
13575 </notes>
13576 <listOfReactants>
13577 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
13578 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13579 </listOfReactants>
13580 <listOfProducts>
13581 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
13582 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
13583 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
13584 </listOfProducts>
13585 </reaction>
13586 <reaction id="R_NTPP7" name="R_Nucleoside_triphosphate_pyrophosphorylase__dttp_" reversible="false">
13587 <notes>
13588 <html:p>GENE_ASSOCIATION: b2781</html:p>
13589 <html:p>PROTEIN_ASSOCIATION: MazG</html:p>
13590 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13591 <html:p>PROTEIN_CLASS: </html:p>
13592 </notes>
13593 <listOfReactants>
13594 <speciesReference species="M_dttp_c" stoichiometry="1.000000"/>
13595 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13596 </listOfReactants>
13597 <listOfProducts>
13598 <speciesReference species="M_dtmp_c" stoichiometry="1.000000"/>
13599 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
13600 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
13601 </listOfProducts>
13602 </reaction>
13603 <reaction id="R_NTPP8" name="R_Nucleoside_triphosphate_pyrophosphorylase__utp_" reversible="false">
13604 <notes>
13605 <html:p>GENE_ASSOCIATION: b2781</html:p>
13606 <html:p>PROTEIN_ASSOCIATION: MazG</html:p>
13607 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13608 <html:p>PROTEIN_CLASS: </html:p>
13609 </notes>
13610 <listOfReactants>
13611 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13612 <speciesReference species="M_utp_c" stoichiometry="1.000000"/>
13613 </listOfReactants>
13614 <listOfProducts>
13615 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
13616 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
13617 <speciesReference species="M_ump_c" stoichiometry="1.000000"/>
13618 </listOfProducts>
13619 </reaction>
13620 <reaction id="R_NTPTP1" name="R_Nucleoside_triphosphate_tripolyhydrolase" reversible="false">
13621 <notes>
13622 <html:p>GENE_ASSOCIATION: b0160</html:p>
13623 <html:p>PROTEIN_ASSOCIATION: Dgt</html:p>
13624 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13625 <html:p>PROTEIN_CLASS: 3.1.5.1</html:p>
13626 </notes>
13627 <listOfReactants>
13628 <speciesReference species="M_dgtp_c" stoichiometry="1.000000"/>
13629 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13630 </listOfReactants>
13631 <listOfProducts>
13632 <speciesReference species="M_dgsn_c" stoichiometry="1.000000"/>
13633 <speciesReference species="M_pppi_c" stoichiometry="1.000000"/>
13634 </listOfProducts>
13635 </reaction>
13636 <reaction id="R_NTPTP2" name="R_Nucleoside_triphosphate_tripolyhydrolase" reversible="false">
13637 <notes>
13638 <html:p>GENE_ASSOCIATION: b0160</html:p>
13639 <html:p>PROTEIN_ASSOCIATION: Dgt</html:p>
13640 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
13641 <html:p>PROTEIN_CLASS: 3.1.5.1</html:p>
13642 </notes>
13643 <listOfReactants>
13644 <speciesReference species="M_gtp_c" stoichiometry="1.000000"/>
13645 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13646 </listOfReactants>
13647 <listOfProducts>
13648 <speciesReference species="M_gsn_c" stoichiometry="1.000000"/>
13649 <speciesReference species="M_pppi_c" stoichiometry="1.000000"/>
13650 </listOfProducts>
13651 </reaction>
13652 <reaction id="R_NTRIR2x" name="R_nitrite_Reductase__NADH_" reversible="false">
13653 <notes>
13654 <html:p>GENE_ASSOCIATION: ( b3365 and b3366 )</html:p>
13655 <html:p>PROTEIN_ASSOCIATION: NirBD</html:p>
13656 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
13657 <html:p>PROTEIN_CLASS: </html:p>
13658 </notes>
13659 <listOfReactants>
13660 <speciesReference species="M_h_c" stoichiometry="5.000000"/>
13661 <speciesReference species="M_nadh_c" stoichiometry="3.000000"/>
13662 <speciesReference species="M_no2_c" stoichiometry="1.000000"/>
13663 </listOfReactants>
13664 <listOfProducts>
13665 <speciesReference species="M_h2o_c" stoichiometry="2.000000"/>
13666 <speciesReference species="M_nad_c" stoichiometry="3.000000"/>
13667 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
13668 </listOfProducts>
13669 </reaction>
13670 <reaction id="R_O2t" name="R_o2_transport__diffusion_" reversible="true">
13671 <notes>
13672 <html:p>GENE_ASSOCIATION: </html:p>
13673 <html:p>PROTEIN_ASSOCIATION: </html:p>
13674 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
13675 <html:p>PROTEIN_CLASS: </html:p>
13676 </notes>
13677 <listOfReactants>
13678 <speciesReference species="M_o2_e" stoichiometry="1.000000"/>
13679 </listOfReactants>
13680 <listOfProducts>
13681 <speciesReference species="M_o2_c" stoichiometry="1.000000"/>
13682 </listOfProducts>
13683 </reaction>
13684 <reaction id="R_OBTFL" name="R_2_Oxobutanoate_formate_lyase" reversible="false">
13685 <notes>
13686 <html:p>GENE_ASSOCIATION: ( b3114 or ( b0902 and b0903 ) )</html:p>
13687 <html:p>PROTEIN_ASSOCIATION: ( TdcE ) or ( PflA )</html:p>
13688 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
13689 <html:p>PROTEIN_CLASS: </html:p>
13690 </notes>
13691 <listOfReactants>
13692 <speciesReference species="M_2obut_c" stoichiometry="1.000000"/>
13693 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
13694 </listOfReactants>
13695 <listOfProducts>
13696 <speciesReference species="M_for_c" stoichiometry="1.000000"/>
13697 <speciesReference species="M_ppcoa_c" stoichiometry="1.000000"/>
13698 </listOfProducts>
13699 </reaction>
13700 <reaction id="R_OCBT" name="R_ornithine_carbamoyltransferase" reversible="true">
13701 <notes>
13702 <html:p>GENE_ASSOCIATION: ( b4254 or b0273 )</html:p>
13703 <html:p>PROTEIN_ASSOCIATION: ( ArgI ) or ( ArgF )</html:p>
13704 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
13705 <html:p>PROTEIN_CLASS: 2.1.3.3</html:p>
13706 </notes>
13707 <listOfReactants>
13708 <speciesReference species="M_cbp_c" stoichiometry="1.000000"/>
13709 <speciesReference species="M_orn_c" stoichiometry="1.000000"/>
13710 </listOfReactants>
13711 <listOfProducts>
13712 <speciesReference species="M_citr_L_c" stoichiometry="1.000000"/>
13713 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
13714 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
13715 </listOfProducts>
13716 </reaction>
13717 <reaction id="R_OCDCAt2" name="R_Octadecanoate_transport_via_proton_symport" reversible="false">
13718 <notes>
13719 <html:p>GENE_ASSOCIATION: b2344</html:p>
13720 <html:p>PROTEIN_ASSOCIATION: FadL</html:p>
13721 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
13722 <html:p>PROTEIN_CLASS: </html:p>
13723 </notes>
13724 <listOfReactants>
13725 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
13726 <speciesReference species="M_ocdca_e" stoichiometry="1.000000"/>
13727 </listOfReactants>
13728 <listOfProducts>
13729 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
13730 <speciesReference species="M_ocdca_c" stoichiometry="1.000000"/>
13731 </listOfProducts>
13732 </reaction>
13733 <reaction id="R_OCTDPS" name="R_Octaprenyl_pyrophosphate_synthase" reversible="false">
13734 <notes>
13735 <html:p>GENE_ASSOCIATION: b3187</html:p>
13736 <html:p>PROTEIN_ASSOCIATION: IspB</html:p>
13737 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
13738 <html:p>PROTEIN_CLASS: </html:p>
13739 </notes>
13740 <listOfReactants>
13741 <speciesReference species="M_frdp_c" stoichiometry="1.000000"/>
13742 <speciesReference species="M_ipdp_c" stoichiometry="5.000000"/>
13743 </listOfReactants>
13744 <listOfProducts>
13745 <speciesReference species="M_octdp_c" stoichiometry="1.000000"/>
13746 <speciesReference species="M_ppi_c" stoichiometry="5.000000"/>
13747 </listOfProducts>
13748 </reaction>
13749 <reaction id="R_OHPBAT" name="R_O_Phospho_4_hydroxy_L_threonine2_oxoglutarate_aminotransferase" reversible="true">
13750 <notes>
13751 <html:p>GENE_ASSOCIATION: b0907</html:p>
13752 <html:p>PROTEIN_ASSOCIATION: SerC</html:p>
13753 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
13754 <html:p>PROTEIN_CLASS: 2.6.1.52</html:p>
13755 </notes>
13756 <listOfReactants>
13757 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
13758 <speciesReference species="M_ohpb_c" stoichiometry="1.000000"/>
13759 </listOfReactants>
13760 <listOfProducts>
13761 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
13762 <speciesReference species="M_phthr_c" stoichiometry="1.000000"/>
13763 </listOfProducts>
13764 </reaction>
13765 <reaction id="R_OHPHM" name="R_2_octaprenyl_6_hydroxyphenol_methylase" reversible="false">
13766 <notes>
13767 <html:p>GENE_ASSOCIATION: b2232</html:p>
13768 <html:p>PROTEIN_ASSOCIATION: UbiG</html:p>
13769 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
13770 <html:p>PROTEIN_CLASS: </html:p>
13771 </notes>
13772 <listOfReactants>
13773 <speciesReference species="M_2ohph_c" stoichiometry="1.000000"/>
13774 <speciesReference species="M_amet_c" stoichiometry="1.000000"/>
13775 </listOfReactants>
13776 <listOfProducts>
13777 <speciesReference species="M_2omph_c" stoichiometry="1.000000"/>
13778 <speciesReference species="M_ahcys_c" stoichiometry="1.000000"/>
13779 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
13780 </listOfProducts>
13781 </reaction>
13782 <reaction id="R_OMBZLM" name="R_2_Octaprenyl_6_methoxy_benzoquinol_methylase" reversible="false">
13783 <notes>
13784 <html:p>GENE_ASSOCIATION: b3833</html:p>
13785 <html:p>PROTEIN_ASSOCIATION: UbiE</html:p>
13786 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
13787 <html:p>PROTEIN_CLASS: </html:p>
13788 </notes>
13789 <listOfReactants>
13790 <speciesReference species="M_2ombzl_c" stoichiometry="1.000000"/>
13791 <speciesReference species="M_amet_c" stoichiometry="1.000000"/>
13792 </listOfReactants>
13793 <listOfProducts>
13794 <speciesReference species="M_2ommbl_c" stoichiometry="1.000000"/>
13795 <speciesReference species="M_ahcys_c" stoichiometry="1.000000"/>
13796 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
13797 </listOfProducts>
13798 </reaction>
13799 <reaction id="R_OMCDC" name="R_2_Oxo_4_methyl_3_carboxypentanoate_decarboxylation" reversible="false">
13800 <notes>
13801 <html:p>GENE_ASSOCIATION: b0073</html:p>
13802 <html:p>PROTEIN_ASSOCIATION: LeuB</html:p>
13803 <html:p>SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism</html:p>
13804 <html:p>PROTEIN_CLASS: </html:p>
13805 </notes>
13806 <listOfReactants>
13807 <speciesReference species="M_3c4mop_c" stoichiometry="1.000000"/>
13808 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
13809 </listOfReactants>
13810 <listOfProducts>
13811 <speciesReference species="M_4mop_c" stoichiometry="1.000000"/>
13812 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
13813 </listOfProducts>
13814 </reaction>
13815 <reaction id="R_OMMBLHX" name="R_2_Octaprenyl_3_methyl_6_methoxy_1_4_benzoquinol_hydroxylase" reversible="false">
13816 <notes>
13817 <html:p>GENE_ASSOCIATION: b0662</html:p>
13818 <html:p>PROTEIN_ASSOCIATION: UbiF</html:p>
13819 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
13820 <html:p>PROTEIN_CLASS: </html:p>
13821 </notes>
13822 <listOfReactants>
13823 <speciesReference species="M_2ommbl_c" stoichiometry="1.000000"/>
13824 <speciesReference species="M_o2_c" stoichiometry="0.500000"/>
13825 </listOfReactants>
13826 <listOfProducts>
13827 <speciesReference species="M_2omhmbl_c" stoichiometry="1.000000"/>
13828 </listOfProducts>
13829 </reaction>
13830 <reaction id="R_OMPDC" name="R_orotidine_5__phosphate_decarboxylase" reversible="false">
13831 <notes>
13832 <html:p>GENE_ASSOCIATION: b1281</html:p>
13833 <html:p>PROTEIN_ASSOCIATION: PyrF</html:p>
13834 <html:p>SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis</html:p>
13835 <html:p>PROTEIN_CLASS: 4.1.1.23</html:p>
13836 </notes>
13837 <listOfReactants>
13838 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
13839 <speciesReference species="M_orot5p_c" stoichiometry="1.000000"/>
13840 </listOfReactants>
13841 <listOfProducts>
13842 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
13843 <speciesReference species="M_ump_c" stoichiometry="1.000000"/>
13844 </listOfProducts>
13845 </reaction>
13846 <reaction id="R_OMPHHX" name="R_2_octaprenyl_6_methoxyphenol_hydroxylase" reversible="false">
13847 <notes>
13848 <html:p>GENE_ASSOCIATION: b2907</html:p>
13849 <html:p>PROTEIN_ASSOCIATION: UbiH</html:p>
13850 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
13851 <html:p>PROTEIN_CLASS: </html:p>
13852 </notes>
13853 <listOfReactants>
13854 <speciesReference species="M_2omph_c" stoichiometry="1.000000"/>
13855 <speciesReference species="M_o2_c" stoichiometry="0.500000"/>
13856 </listOfReactants>
13857 <listOfProducts>
13858 <speciesReference species="M_2ombzl_c" stoichiometry="1.000000"/>
13859 </listOfProducts>
13860 </reaction>
13861 <reaction id="R_OP4ENH" name="R_2_oxopent_4_enoate_hydratase" reversible="false">
13862 <notes>
13863 <html:p>GENE_ASSOCIATION: b0350</html:p>
13864 <html:p>PROTEIN_ASSOCIATION: MhpD</html:p>
13865 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
13866 <html:p>PROTEIN_CLASS: 4.2.1.80</html:p>
13867 </notes>
13868 <listOfReactants>
13869 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13870 <speciesReference species="M_op4en_c" stoichiometry="1.000000"/>
13871 </listOfReactants>
13872 <listOfProducts>
13873 <speciesReference species="M_4h2opntn_c" stoichiometry="1.000000"/>
13874 </listOfProducts>
13875 </reaction>
13876 <reaction id="R_OPHBDC" name="R_Octaprenyl_hydroxybenzoate_decarboxylase" reversible="false">
13877 <notes>
13878 <html:p>GENE_ASSOCIATION: ( b3843 or b2311 )</html:p>
13879 <html:p>PROTEIN_ASSOCIATION: ( UbiD ) or ( UbiX )</html:p>
13880 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
13881 <html:p>PROTEIN_CLASS: </html:p>
13882 </notes>
13883 <listOfReactants>
13884 <speciesReference species="M_3ophb_c" stoichiometry="1.000000"/>
13885 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
13886 </listOfReactants>
13887 <listOfProducts>
13888 <speciesReference species="M_2oph_c" stoichiometry="1.000000"/>
13889 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
13890 </listOfProducts>
13891 </reaction>
13892 <reaction id="R_OPHHX" name="R_2_Octaprenylphenol_hydroxylase" reversible="false">
13893 <notes>
13894 <html:p>GENE_ASSOCIATION: b3835</html:p>
13895 <html:p>PROTEIN_ASSOCIATION: UbiB</html:p>
13896 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
13897 <html:p>PROTEIN_CLASS: </html:p>
13898 </notes>
13899 <listOfReactants>
13900 <speciesReference species="M_2oph_c" stoichiometry="1.000000"/>
13901 <speciesReference species="M_o2_c" stoichiometry="0.500000"/>
13902 </listOfReactants>
13903 <listOfProducts>
13904 <speciesReference species="M_2ohph_c" stoichiometry="1.000000"/>
13905 </listOfProducts>
13906 </reaction>
13907 <reaction id="R_ORNDC" name="R_Ornithine_Decarboxylase" reversible="false">
13908 <notes>
13909 <html:p>GENE_ASSOCIATION: ( b2965 or b0693 )</html:p>
13910 <html:p>PROTEIN_ASSOCIATION: ( SpeC ) or ( SpeF )</html:p>
13911 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
13912 <html:p>PROTEIN_CLASS: 4.1.1.17</html:p>
13913 </notes>
13914 <listOfReactants>
13915 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
13916 <speciesReference species="M_orn_c" stoichiometry="1.000000"/>
13917 </listOfReactants>
13918 <listOfProducts>
13919 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
13920 <speciesReference species="M_ptrc_c" stoichiometry="1.000000"/>
13921 </listOfProducts>
13922 </reaction>
13923 <reaction id="R_ORNTA" name="R_ornithine_transaminase" reversible="false">
13924 <notes>
13925 <html:p>GENE_ASSOCIATION: b3073</html:p>
13926 <html:p>PROTEIN_ASSOCIATION: YgjG</html:p>
13927 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
13928 <html:p>PROTEIN_CLASS: 2.6.1.13</html:p>
13929 </notes>
13930 <listOfReactants>
13931 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
13932 <speciesReference species="M_orn_c" stoichiometry="1.000000"/>
13933 </listOfReactants>
13934 <listOfProducts>
13935 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
13936 <speciesReference species="M_glu5sa_c" stoichiometry="1.000000"/>
13937 </listOfProducts>
13938 </reaction>
13939 <reaction id="R_ORNabc" name="R_ornithine_transport_via_ABC_system" reversible="false">
13940 <notes>
13941 <html:p>GENE_ASSOCIATION: ( b2310 and b2307 and b2306 and b2308 )</html:p>
13942 <html:p>PROTEIN_ASSOCIATION: ( ArgT and HisM and HisP and HisQ )</html:p>
13943 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
13944 <html:p>PROTEIN_CLASS: </html:p>
13945 </notes>
13946 <listOfReactants>
13947 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
13948 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
13949 <speciesReference species="M_orn_e" stoichiometry="1.000000"/>
13950 </listOfReactants>
13951 <listOfProducts>
13952 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
13953 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
13954 <speciesReference species="M_orn_c" stoichiometry="1.000000"/>
13955 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
13956 </listOfProducts>
13957 </reaction>
13958 <reaction id="R_ORPT" name="R_orotate_phosphoribosyltransferase" reversible="true">
13959 <notes>
13960 <html:p>GENE_ASSOCIATION: b3642</html:p>
13961 <html:p>PROTEIN_ASSOCIATION: PyrE</html:p>
13962 <html:p>SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis</html:p>
13963 <html:p>PROTEIN_CLASS: 2.4.2.10</html:p>
13964 </notes>
13965 <listOfReactants>
13966 <speciesReference species="M_orot5p_c" stoichiometry="1.000000"/>
13967 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
13968 </listOfReactants>
13969 <listOfProducts>
13970 <speciesReference species="M_orot_c" stoichiometry="1.000000"/>
13971 <speciesReference species="M_prpp_c" stoichiometry="1.000000"/>
13972 </listOfProducts>
13973 </reaction>
13974 <reaction id="R_OXGDC2" name="R_2_oxoglutarate_decarboxylase" reversible="false">
13975 <notes>
13976 <html:p>GENE_ASSOCIATION: b2264</html:p>
13977 <html:p>PROTEIN_ASSOCIATION: MenD</html:p>
13978 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
13979 <html:p>PROTEIN_CLASS: 4.1.1.71</html:p>
13980 </notes>
13981 <listOfReactants>
13982 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
13983 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
13984 <speciesReference species="M_thmpp_c" stoichiometry="1.000000"/>
13985 </listOfReactants>
13986 <listOfProducts>
13987 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
13988 <speciesReference species="M_ssaltpp_c" stoichiometry="1.000000"/>
13989 </listOfProducts>
13990 </reaction>
13991 <reaction id="R_P5CD" name="R_1_pyrroline_5_carboxylate_dehydrogenase" reversible="false">
13992 <notes>
13993 <html:p>GENE_ASSOCIATION: b1014</html:p>
13994 <html:p>PROTEIN_ASSOCIATION: PutAec</html:p>
13995 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
13996 <html:p>PROTEIN_CLASS: 1.5.1.12</html:p>
13997 </notes>
13998 <listOfReactants>
13999 <speciesReference species="M_1pyr5c_c" stoichiometry="1.000000"/>
14000 <speciesReference species="M_h2o_c" stoichiometry="2.000000"/>
14001 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
14002 </listOfReactants>
14003 <listOfProducts>
14004 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
14005 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14006 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
14007 </listOfProducts>
14008 </reaction>
14009 <reaction id="R_P5CR" name="R_pyrroline_5_carboxylate_reductase" reversible="false">
14010 <notes>
14011 <html:p>GENE_ASSOCIATION: b0386</html:p>
14012 <html:p>PROTEIN_ASSOCIATION: ProC</html:p>
14013 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
14014 <html:p>PROTEIN_CLASS: 1.5.1.2</html:p>
14015 </notes>
14016 <listOfReactants>
14017 <speciesReference species="M_1pyr5c_c" stoichiometry="1.000000"/>
14018 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
14019 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
14020 </listOfReactants>
14021 <listOfProducts>
14022 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
14023 <speciesReference species="M_pro_L_c" stoichiometry="1.000000"/>
14024 </listOfProducts>
14025 </reaction>
14026 <reaction id="R_PACCOAL" name="R_phenylacetate_CoA_ligase" reversible="false">
14027 <notes>
14028 <html:p>GENE_ASSOCIATION: b1398</html:p>
14029 <html:p>PROTEIN_ASSOCIATION: PaaK</html:p>
14030 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
14031 <html:p>PROTEIN_CLASS: 6.2.1.30</html:p>
14032 </notes>
14033 <listOfReactants>
14034 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
14035 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
14036 <speciesReference species="M_pac_c" stoichiometry="1.000000"/>
14037 </listOfReactants>
14038 <listOfProducts>
14039 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
14040 <speciesReference species="M_phaccoa_c" stoichiometry="1.000000"/>
14041 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
14042 </listOfProducts>
14043 </reaction>
14044 <reaction id="R_PANTS" name="R_pantothenate_synthase" reversible="false">
14045 <notes>
14046 <html:p>GENE_ASSOCIATION: b0133</html:p>
14047 <html:p>PROTEIN_ASSOCIATION: PanCec</html:p>
14048 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
14049 <html:p>PROTEIN_CLASS: 6.3.2.1</html:p>
14050 </notes>
14051 <listOfReactants>
14052 <speciesReference species="M_ala_B_c" stoichiometry="1.000000"/>
14053 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
14054 <speciesReference species="M_pant_R_c" stoichiometry="1.000000"/>
14055 </listOfReactants>
14056 <listOfProducts>
14057 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
14058 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14059 <speciesReference species="M_pnto_R_c" stoichiometry="1.000000"/>
14060 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
14061 </listOfProducts>
14062 </reaction>
14063 <reaction id="R_PAPA_EC" name="R_Phosphatidate_phosphatase" reversible="false">
14064 <notes>
14065 <html:p>GENE_ASSOCIATION: </html:p>
14066 <html:p>PROTEIN_ASSOCIATION: </html:p>
14067 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
14068 <html:p>PROTEIN_CLASS: 3.1.3.4</html:p>
14069 </notes>
14070 <listOfReactants>
14071 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
14072 <speciesReference species="M_pa_EC_c" stoichiometry="0.020000"/>
14073 </listOfReactants>
14074 <listOfProducts>
14075 <speciesReference species="M_12dgr_EC_c" stoichiometry="0.020000"/>
14076 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
14077 </listOfProducts>
14078 </reaction>
14079 <reaction id="R_PAPPT3" name="R_phospho_N_acetylmuramoyl_pentapeptide_transferase__meso_2_6_diaminopimelate_" reversible="false">
14080 <notes>
14081 <html:p>GENE_ASSOCIATION: b0087</html:p>
14082 <html:p>PROTEIN_ASSOCIATION: MraY</html:p>
14083 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
14084 <html:p>PROTEIN_CLASS: 2.7.8.13</html:p>
14085 </notes>
14086 <listOfReactants>
14087 <speciesReference species="M_udcpp_c" stoichiometry="1.000000"/>
14088 <speciesReference species="M_ugmda_c" stoichiometry="1.000000"/>
14089 </listOfReactants>
14090 <listOfProducts>
14091 <speciesReference species="M_uagmda_c" stoichiometry="1.000000"/>
14092 <speciesReference species="M_ump_c" stoichiometry="1.000000"/>
14093 </listOfProducts>
14094 </reaction>
14095 <reaction id="R_PAPSR" name="R_phosphoadenylyl_sulfate_reductase__thioredoxin_" reversible="false">
14096 <notes>
14097 <html:p>GENE_ASSOCIATION: b2762</html:p>
14098 <html:p>PROTEIN_ASSOCIATION: CysH</html:p>
14099 <html:p>SUBSYSTEM: S_Cysteine_Metabolism</html:p>
14100 <html:p>PROTEIN_CLASS: 1.8.4.8</html:p>
14101 </notes>
14102 <listOfReactants>
14103 <speciesReference species="M_paps_c" stoichiometry="1.000000"/>
14104 <speciesReference species="M_trdrd_c" stoichiometry="1.000000"/>
14105 </listOfReactants>
14106 <listOfProducts>
14107 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
14108 <speciesReference species="M_pap_c" stoichiometry="1.000000"/>
14109 <speciesReference species="M_so3_c" stoichiometry="1.000000"/>
14110 <speciesReference species="M_trdox_c" stoichiometry="1.000000"/>
14111 </listOfProducts>
14112 </reaction>
14113 <reaction id="R_PASYN_EC" name="R_Phosphatidic_acid_synthase__Ecoli_" reversible="false">
14114 <notes>
14115 <html:p>GENE_ASSOCIATION: ( b4041 and b3018 )</html:p>
14116 <html:p>PROTEIN_ASSOCIATION: ( PlsBec and PlsC )</html:p>
14117 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
14118 <html:p>PROTEIN_CLASS: </html:p>
14119 </notes>
14120 <listOfReactants>
14121 <speciesReference species="M_glyc3p_c" stoichiometry="1.000000"/>
14122 <speciesReference species="M_hdeACP_c" stoichiometry="0.140000"/>
14123 <speciesReference species="M_myrsACP_c" stoichiometry="0.040000"/>
14124 <speciesReference species="M_octeACP_c" stoichiometry="1.000000"/>
14125 <speciesReference species="M_palmACP_c" stoichiometry="0.720000"/>
14126 <speciesReference species="M_tdeACP_c" stoichiometry="0.100000"/>
14127 </listOfReactants>
14128 <listOfProducts>
14129 <speciesReference species="M_ACP_c" stoichiometry="2.000000"/>
14130 <speciesReference species="M_pa_EC_c" stoichiometry="0.020000"/>
14131 </listOfProducts>
14132 </reaction>
14133 <reaction id="R_PDH" name="R_pyruvate_dehydrogenase" reversible="false">
14134 <notes>
14135 <html:p>GENE_ASSOCIATION: ( b0114 and b0115 and b0116 )</html:p>
14136 <html:p>PROTEIN_ASSOCIATION: ( AceEec and AceFec and LpdA )</html:p>
14137 <html:p>SUBSYSTEM: S_GlycolysisGluconeogenesis</html:p>
14138 <html:p>PROTEIN_CLASS: </html:p>
14139 </notes>
14140 <listOfReactants>
14141 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
14142 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
14143 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
14144 </listOfReactants>
14145 <listOfProducts>
14146 <speciesReference species="M_accoa_c" stoichiometry="1.000000"/>
14147 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
14148 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
14149 </listOfProducts>
14150 </reaction>
14151 <reaction id="R_PDX5PO" name="R_pyridoxine_5__phosphate_oxidase" reversible="true">
14152 <notes>
14153 <html:p>GENE_ASSOCIATION: b1638</html:p>
14154 <html:p>PROTEIN_ASSOCIATION: PdxHec</html:p>
14155 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
14156 <html:p>PROTEIN_CLASS: 1.4.3.5</html:p>
14157 </notes>
14158 <listOfReactants>
14159 <speciesReference species="M_o2_c" stoichiometry="1.000000"/>
14160 <speciesReference species="M_pdx5p_c" stoichiometry="1.000000"/>
14161 </listOfReactants>
14162 <listOfProducts>
14163 <speciesReference species="M_h2o2_c" stoichiometry="1.000000"/>
14164 <speciesReference species="M_pydx5p_c" stoichiometry="1.000000"/>
14165 </listOfProducts>
14166 </reaction>
14167 <reaction id="R_PDX5PS" name="R_Pyridoxine_5__phosphate_synthase" reversible="false">
14168 <notes>
14169 <html:p>GENE_ASSOCIATION: ( b0052 and b2564 )</html:p>
14170 <html:p>PROTEIN_ASSOCIATION: PdxAJ</html:p>
14171 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
14172 <html:p>PROTEIN_CLASS: </html:p>
14173 </notes>
14174 <listOfReactants>
14175 <speciesReference species="M_dxyl5p_c" stoichiometry="1.000000"/>
14176 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
14177 <speciesReference species="M_phthr_c" stoichiometry="1.000000"/>
14178 </listOfReactants>
14179 <listOfProducts>
14180 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
14181 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14182 <speciesReference species="M_h2o_c" stoichiometry="2.000000"/>
14183 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
14184 <speciesReference species="M_pdx5p_c" stoichiometry="1.000000"/>
14185 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
14186 </listOfProducts>
14187 </reaction>
14188 <reaction id="R_PDXPP" name="R_Pyridoxine_5_phosphate_phosphatase" reversible="false">
14189 <notes>
14190 <html:p>GENE_ASSOCIATION: </html:p>
14191 <html:p>PROTEIN_ASSOCIATION: </html:p>
14192 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
14193 <html:p>PROTEIN_CLASS: </html:p>
14194 </notes>
14195 <listOfReactants>
14196 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
14197 <speciesReference species="M_pdx5p_c" stoichiometry="1.000000"/>
14198 </listOfReactants>
14199 <listOfProducts>
14200 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
14201 <speciesReference species="M_pydxn_c" stoichiometry="1.000000"/>
14202 </listOfProducts>
14203 </reaction>
14204 <reaction id="R_PEAMNO" name="R_Phenethylamine_oxidase" reversible="false">
14205 <notes>
14206 <html:p>GENE_ASSOCIATION: b1386</html:p>
14207 <html:p>PROTEIN_ASSOCIATION: TynA</html:p>
14208 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
14209 <html:p>PROTEIN_CLASS: 1.4.3.6</html:p>
14210 </notes>
14211 <listOfReactants>
14212 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
14213 <speciesReference species="M_o2_c" stoichiometry="1.000000"/>
14214 <speciesReference species="M_peamn_c" stoichiometry="1.000000"/>
14215 </listOfReactants>
14216 <listOfProducts>
14217 <speciesReference species="M_h2o2_c" stoichiometry="1.000000"/>
14218 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
14219 <speciesReference species="M_pacald_c" stoichiometry="1.000000"/>
14220 </listOfProducts>
14221 </reaction>
14222 <reaction id="R_PEPT_EC" name="R_ethanolamine_phosphotransferase" reversible="true">
14223 <notes>
14224 <html:p>GENE_ASSOCIATION: </html:p>
14225 <html:p>PROTEIN_ASSOCIATION: </html:p>
14226 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
14227 <html:p>PROTEIN_CLASS: 2.7.8.1</html:p>
14228 </notes>
14229 <listOfReactants>
14230 <speciesReference species="M_cmp_c" stoichiometry="1.000000"/>
14231 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14232 <speciesReference species="M_pe_EC_c" stoichiometry="0.020000"/>
14233 </listOfReactants>
14234 <listOfProducts>
14235 <speciesReference species="M_12dgr_EC_c" stoichiometry="0.020000"/>
14236 <speciesReference species="M_cdpea_c" stoichiometry="1.000000"/>
14237 </listOfProducts>
14238 </reaction>
14239 <reaction id="R_PERD" name="R_Erythronate_4_phosphate__4per__dehydrogenase" reversible="true">
14240 <notes>
14241 <html:p>GENE_ASSOCIATION: b2320</html:p>
14242 <html:p>PROTEIN_ASSOCIATION: PdxB</html:p>
14243 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
14244 <html:p>PROTEIN_CLASS: </html:p>
14245 </notes>
14246 <listOfReactants>
14247 <speciesReference species="M_4per_c" stoichiometry="1.000000"/>
14248 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
14249 </listOfReactants>
14250 <listOfProducts>
14251 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14252 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
14253 <speciesReference species="M_ohpb_c" stoichiometry="1.000000"/>
14254 </listOfProducts>
14255 </reaction>
14256 <reaction id="R_PFK" name="R_phosphofructokinase" reversible="false">
14257 <notes>
14258 <html:p>GENE_ASSOCIATION: ( b3916 or b1723 )</html:p>
14259 <html:p>PROTEIN_ASSOCIATION: ( PfkA ) or ( PfkB )</html:p>
14260 <html:p>SUBSYSTEM: S_GlycolysisGluconeogenesis</html:p>
14261 <html:p>PROTEIN_CLASS: 2.7.1.11</html:p>
14262 </notes>
14263 <listOfReactants>
14264 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
14265 <speciesReference species="M_f6p_c" stoichiometry="1.000000"/>
14266 </listOfReactants>
14267 <listOfProducts>
14268 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
14269 <speciesReference species="M_fdp_c" stoichiometry="1.000000"/>
14270 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14271 </listOfProducts>
14272 </reaction>
14273 <reaction id="R_PFK_2" name="R_Phosphofructokinase" reversible="false">
14274 <notes>
14275 <html:p>GENE_ASSOCIATION: ( b1723 or b2168 or ( b3132 and b3137 ) )</html:p>
14276 <html:p>PROTEIN_ASSOCIATION: ( PfkB ) or ( FruK ) or ( AgaZ )</html:p>
14277 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
14278 <html:p>PROTEIN_CLASS: 2.7.1.11</html:p>
14279 </notes>
14280 <listOfReactants>
14281 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
14282 <speciesReference species="M_tag6p_D_c" stoichiometry="1.000000"/>
14283 </listOfReactants>
14284 <listOfProducts>
14285 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
14286 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14287 <speciesReference species="M_tagdp_D_c" stoichiometry="1.000000"/>
14288 </listOfProducts>
14289 </reaction>
14290 <reaction id="R_PFL" name="R_pyruvate_formate_lyase" reversible="false">
14291 <notes>
14292 <html:p>GENE_ASSOCIATION: ( ( b3951 and b3952 ) or b3114 or ( b0902 and b0903 ) )</html:p>
14293 <html:p>PROTEIN_ASSOCIATION: ( PflC ) or ( TdcE ) or ( PflA )</html:p>
14294 <html:p>SUBSYSTEM: S_Pyruvate_Metabolism</html:p>
14295 <html:p>PROTEIN_CLASS: </html:p>
14296 </notes>
14297 <listOfReactants>
14298 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
14299 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
14300 </listOfReactants>
14301 <listOfProducts>
14302 <speciesReference species="M_accoa_c" stoichiometry="1.000000"/>
14303 <speciesReference species="M_for_c" stoichiometry="1.000000"/>
14304 </listOfProducts>
14305 </reaction>
14306 <reaction id="R_PGAMT" name="R_phosphoglucosamine_mutase" reversible="true">
14307 <notes>
14308 <html:p>GENE_ASSOCIATION: b3176</html:p>
14309 <html:p>PROTEIN_ASSOCIATION: MrsA</html:p>
14310 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
14311 <html:p>PROTEIN_CLASS: 5.4.2.10</html:p>
14312 </notes>
14313 <listOfReactants>
14314 <speciesReference species="M_gam1p_c" stoichiometry="1.000000"/>
14315 </listOfReactants>
14316 <listOfProducts>
14317 <speciesReference species="M_gam6p_c" stoichiometry="1.000000"/>
14318 </listOfProducts>
14319 </reaction>
14320 <reaction id="R_PGCD" name="R_phosphoglycerate_dehydrogenase" reversible="false">
14321 <notes>
14322 <html:p>GENE_ASSOCIATION: b2913</html:p>
14323 <html:p>PROTEIN_ASSOCIATION: SerA</html:p>
14324 <html:p>SUBSYSTEM: S_Glycine_and_Serine_Metabolism</html:p>
14325 <html:p>PROTEIN_CLASS: 1.1.1.95</html:p>
14326 </notes>
14327 <listOfReactants>
14328 <speciesReference species="M_3pg_c" stoichiometry="1.000000"/>
14329 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
14330 </listOfReactants>
14331 <listOfProducts>
14332 <speciesReference species="M_3php_c" stoichiometry="1.000000"/>
14333 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14334 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
14335 </listOfProducts>
14336 </reaction>
14337 <reaction id="R_PGI" name="R_glucose_6_phosphate_isomerase" reversible="true">
14338 <notes>
14339 <html:p>GENE_ASSOCIATION: b4025</html:p>
14340 <html:p>PROTEIN_ASSOCIATION: Pgi</html:p>
14341 <html:p>SUBSYSTEM: S_GlycolysisGluconeogenesis</html:p>
14342 <html:p>PROTEIN_CLASS: 5.3.1.9</html:p>
14343 </notes>
14344 <listOfReactants>
14345 <speciesReference species="M_g6p_c" stoichiometry="1.000000"/>
14346 </listOfReactants>
14347 <listOfProducts>
14348 <speciesReference species="M_f6p_c" stoichiometry="1.000000"/>
14349 </listOfProducts>
14350 </reaction>
14351 <reaction id="R_PGK" name="R_phosphoglycerate_kinase" reversible="true">
14352 <notes>
14353 <html:p>GENE_ASSOCIATION: b2926</html:p>
14354 <html:p>PROTEIN_ASSOCIATION: Pgk</html:p>
14355 <html:p>SUBSYSTEM: S_GlycolysisGluconeogenesis</html:p>
14356 <html:p>PROTEIN_CLASS: 2.7.2.3</html:p>
14357 </notes>
14358 <listOfReactants>
14359 <speciesReference species="M_3pg_c" stoichiometry="1.000000"/>
14360 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
14361 </listOfReactants>
14362 <listOfProducts>
14363 <speciesReference species="M_13dpg_c" stoichiometry="1.000000"/>
14364 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
14365 </listOfProducts>
14366 </reaction>
14367 <reaction id="R_PGL" name="R_6_phosphogluconolactonase" reversible="false">
14368 <notes>
14369 <html:p>GENE_ASSOCIATION: </html:p>
14370 <html:p>PROTEIN_ASSOCIATION: </html:p>
14371 <html:p>SUBSYSTEM: S_Pentose_Phosphate_Pathway</html:p>
14372 <html:p>PROTEIN_CLASS: 3.1.1.31</html:p>
14373 </notes>
14374 <listOfReactants>
14375 <speciesReference species="M_6pgl_c" stoichiometry="1.000000"/>
14376 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
14377 </listOfReactants>
14378 <listOfProducts>
14379 <speciesReference species="M_6pgc_c" stoichiometry="1.000000"/>
14380 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14381 </listOfProducts>
14382 </reaction>
14383 <reaction id="R_PGLYCP" name="R_Phosphoglycolate_phosphatase" reversible="false">
14384 <notes>
14385 <html:p>GENE_ASSOCIATION: b3385</html:p>
14386 <html:p>PROTEIN_ASSOCIATION: Gph</html:p>
14387 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
14388 <html:p>PROTEIN_CLASS: 3.1.3.18</html:p>
14389 </notes>
14390 <listOfReactants>
14391 <speciesReference species="M_2pglyc_c" stoichiometry="1.000000"/>
14392 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
14393 </listOfReactants>
14394 <listOfProducts>
14395 <speciesReference species="M_glyclt_c" stoichiometry="1.000000"/>
14396 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
14397 </listOfProducts>
14398 </reaction>
14399 <reaction id="R_PGM" name="R_phosphoglycerate_mutase" reversible="true">
14400 <notes>
14401 <html:p>GENE_ASSOCIATION: ( b4395 or b0755 or b3612 )</html:p>
14402 <html:p>PROTEIN_ASSOCIATION: ( GpmB ) or ( GpmA ) or ( YibO )</html:p>
14403 <html:p>SUBSYSTEM: S_GlycolysisGluconeogenesis</html:p>
14404 <html:p>PROTEIN_CLASS: 5.4.2.1</html:p>
14405 </notes>
14406 <listOfReactants>
14407 <speciesReference species="M_2pg_c" stoichiometry="1.000000"/>
14408 </listOfReactants>
14409 <listOfProducts>
14410 <speciesReference species="M_3pg_c" stoichiometry="1.000000"/>
14411 </listOfProducts>
14412 </reaction>
14413 <reaction id="R_PGMT" name="R_phosphoglucomutase" reversible="true">
14414 <notes>
14415 <html:p>GENE_ASSOCIATION: ( b0688 or b2690 )</html:p>
14416 <html:p>PROTEIN_ASSOCIATION: ( Pgmec ) or ( YqaB )</html:p>
14417 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
14418 <html:p>PROTEIN_CLASS: 5.4.2.2</html:p>
14419 </notes>
14420 <listOfReactants>
14421 <speciesReference species="M_g1p_c" stoichiometry="1.000000"/>
14422 </listOfReactants>
14423 <listOfProducts>
14424 <speciesReference species="M_g6p_c" stoichiometry="1.000000"/>
14425 </listOfProducts>
14426 </reaction>
14427 <reaction id="R_PGPP_EC" name="R_Phosphatidylglycerol_phosphate_phosphatase__Ecoli_" reversible="false">
14428 <notes>
14429 <html:p>GENE_ASSOCIATION: ( b0418 or b1278 )</html:p>
14430 <html:p>PROTEIN_ASSOCIATION: ( PgpAec ) or ( PgpBec )</html:p>
14431 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
14432 <html:p>PROTEIN_CLASS: 3.1.3.27</html:p>
14433 </notes>
14434 <listOfReactants>
14435 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
14436 <speciesReference species="M_pgp_EC_c" stoichiometry="0.020000"/>
14437 </listOfReactants>
14438 <listOfProducts>
14439 <speciesReference species="M_pg_EC_c" stoichiometry="0.020000"/>
14440 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
14441 </listOfProducts>
14442 </reaction>
14443 <reaction id="R_PGSA_EC" name="R_Phosphatidylglycerol_synthase__Ecoli_" reversible="true">
14444 <notes>
14445 <html:p>GENE_ASSOCIATION: b1912</html:p>
14446 <html:p>PROTEIN_ASSOCIATION: PgsA</html:p>
14447 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
14448 <html:p>PROTEIN_CLASS: 2.7.8.5</html:p>
14449 </notes>
14450 <listOfReactants>
14451 <speciesReference species="M_cdpdag_EC_c" stoichiometry="0.020000"/>
14452 <speciesReference species="M_glyc3p_c" stoichiometry="1.000000"/>
14453 </listOfReactants>
14454 <listOfProducts>
14455 <speciesReference species="M_cmp_c" stoichiometry="1.000000"/>
14456 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14457 <speciesReference species="M_pgp_EC_c" stoichiometry="0.020000"/>
14458 </listOfProducts>
14459 </reaction>
14460 <reaction id="R_PHETA1" name="R_phenylalanine_transaminase" reversible="true">
14461 <notes>
14462 <html:p>GENE_ASSOCIATION: ( b4054 or b3770 or b0928 )</html:p>
14463 <html:p>PROTEIN_ASSOCIATION: ( TyrB ) or ( IlvE ) or ( AspC )</html:p>
14464 <html:p>SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism</html:p>
14465 <html:p>PROTEIN_CLASS: 2.6.1.58</html:p>
14466 </notes>
14467 <listOfReactants>
14468 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
14469 <speciesReference species="M_phe_L_c" stoichiometry="1.000000"/>
14470 </listOfReactants>
14471 <listOfProducts>
14472 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
14473 <speciesReference species="M_phpyr_c" stoichiometry="1.000000"/>
14474 </listOfProducts>
14475 </reaction>
14476 <reaction id="R_PHEt2r" name="R_L_phenylalanine_reversible_transport_via_proton_symport" reversible="true">
14477 <notes>
14478 <html:p>GENE_ASSOCIATION: ( b0112 or b0576 )</html:p>
14479 <html:p>PROTEIN_ASSOCIATION: ( AroP ) or ( PheP )</html:p>
14480 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
14481 <html:p>PROTEIN_CLASS: </html:p>
14482 </notes>
14483 <listOfReactants>
14484 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
14485 <speciesReference species="M_phe_L_e" stoichiometry="1.000000"/>
14486 </listOfReactants>
14487 <listOfProducts>
14488 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14489 <speciesReference species="M_phe_L_c" stoichiometry="1.000000"/>
14490 </listOfProducts>
14491 </reaction>
14492 <reaction id="R_PIabc" name="R_phosphate_transport_via_ABC_system" reversible="false">
14493 <notes>
14494 <html:p>GENE_ASSOCIATION: ( b3726 and b3725 and b3727 and b3728 )</html:p>
14495 <html:p>PROTEIN_ASSOCIATION: ( PstA and PstB and PstC and PstD )</html:p>
14496 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
14497 <html:p>PROTEIN_CLASS: </html:p>
14498 </notes>
14499 <listOfReactants>
14500 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
14501 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
14502 <speciesReference species="M_pi_e" stoichiometry="1.000000"/>
14503 </listOfReactants>
14504 <listOfProducts>
14505 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
14506 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14507 <speciesReference species="M_pi_c" stoichiometry="2.000000"/>
14508 </listOfProducts>
14509 </reaction>
14510 <reaction id="R_PIt2r" name="R_phosphate_reversible_transport_via_symport" reversible="true">
14511 <notes>
14512 <html:p>GENE_ASSOCIATION: ( b3493 or b2987 )</html:p>
14513 <html:p>PROTEIN_ASSOCIATION: ( PitA ) or ( PitBec )</html:p>
14514 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
14515 <html:p>PROTEIN_CLASS: </html:p>
14516 </notes>
14517 <listOfReactants>
14518 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
14519 <speciesReference species="M_pi_e" stoichiometry="1.000000"/>
14520 </listOfReactants>
14521 <listOfProducts>
14522 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14523 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
14524 </listOfProducts>
14525 </reaction>
14526 <reaction id="R_PLIPA1" name="R_Phospholipase_A__phosphatidylglycerol_" reversible="false">
14527 <notes>
14528 <html:p>GENE_ASSOCIATION: b3821</html:p>
14529 <html:p>PROTEIN_ASSOCIATION: PldA</html:p>
14530 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
14531 <html:p>PROTEIN_CLASS: </html:p>
14532 </notes>
14533 <listOfReactants>
14534 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
14535 <speciesReference species="M_pg_EC_c" stoichiometry="0.020000"/>
14536 </listOfReactants>
14537 <listOfProducts>
14538 <speciesReference species="M_agpg_EC_c" stoichiometry="0.020000"/>
14539 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14540 <speciesReference species="M_hdca_c" stoichiometry="0.360000"/>
14541 <speciesReference species="M_hdcea_c" stoichiometry="0.070000"/>
14542 <speciesReference species="M_ocdcea_c" stoichiometry="0.500000"/>
14543 <speciesReference species="M_ttdca_c" stoichiometry="0.020000"/>
14544 <speciesReference species="M_ttdcea_c" stoichiometry="0.050000"/>
14545 </listOfProducts>
14546 </reaction>
14547 <reaction id="R_PLIPA2" name="R_Phosphlipase_A__phosphatidylethanolamine_" reversible="false">
14548 <notes>
14549 <html:p>GENE_ASSOCIATION: b3821</html:p>
14550 <html:p>PROTEIN_ASSOCIATION: PldA</html:p>
14551 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
14552 <html:p>PROTEIN_CLASS: </html:p>
14553 </notes>
14554 <listOfReactants>
14555 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
14556 <speciesReference species="M_pe_EC_c" stoichiometry="0.020000"/>
14557 </listOfReactants>
14558 <listOfProducts>
14559 <speciesReference species="M_agpe_EC_c" stoichiometry="0.020000"/>
14560 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14561 <speciesReference species="M_hdca_c" stoichiometry="0.360000"/>
14562 <speciesReference species="M_hdcea_c" stoichiometry="0.070000"/>
14563 <speciesReference species="M_ocdcea_c" stoichiometry="0.500000"/>
14564 <speciesReference species="M_ttdca_c" stoichiometry="0.020000"/>
14565 <speciesReference species="M_ttdcea_c" stoichiometry="0.050000"/>
14566 </listOfProducts>
14567 </reaction>
14568 <reaction id="R_PLIPA3" name="R_Phospholipase_A__phosphatidylcholine_" reversible="false">
14569 <notes>
14570 <html:p>GENE_ASSOCIATION: b3821</html:p>
14571 <html:p>PROTEIN_ASSOCIATION: PldA</html:p>
14572 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
14573 <html:p>PROTEIN_CLASS: </html:p>
14574 </notes>
14575 <listOfReactants>
14576 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
14577 <speciesReference species="M_pc_EC_c" stoichiometry="0.020000"/>
14578 </listOfReactants>
14579 <listOfProducts>
14580 <speciesReference species="M_agpc_EC_c" stoichiometry="0.020000"/>
14581 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14582 <speciesReference species="M_hdca_c" stoichiometry="0.360000"/>
14583 <speciesReference species="M_hdcea_c" stoichiometry="0.070000"/>
14584 <speciesReference species="M_ocdcea_c" stoichiometry="0.500000"/>
14585 <speciesReference species="M_ttdca_c" stoichiometry="0.020000"/>
14586 <speciesReference species="M_ttdcea_c" stoichiometry="0.050000"/>
14587 </listOfProducts>
14588 </reaction>
14589 <reaction id="R_PMANM" name="R_phosphomannomutase" reversible="true">
14590 <notes>
14591 <html:p>GENE_ASSOCIATION: b2048</html:p>
14592 <html:p>PROTEIN_ASSOCIATION: CpsG</html:p>
14593 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
14594 <html:p>PROTEIN_CLASS: 5.4.2.8</html:p>
14595 </notes>
14596 <listOfReactants>
14597 <speciesReference species="M_man1p_c" stoichiometry="1.000000"/>
14598 </listOfReactants>
14599 <listOfProducts>
14600 <speciesReference species="M_man6p_c" stoichiometry="1.000000"/>
14601 </listOfProducts>
14602 </reaction>
14603 <reaction id="R_PMDPHT" name="R_pyrimidine_phosphatase" reversible="false">
14604 <notes>
14605 <html:p>GENE_ASSOCIATION: </html:p>
14606 <html:p>PROTEIN_ASSOCIATION: </html:p>
14607 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
14608 <html:p>PROTEIN_CLASS: </html:p>
14609 </notes>
14610 <listOfReactants>
14611 <speciesReference species="M_5aprbu_c" stoichiometry="1.000000"/>
14612 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
14613 </listOfReactants>
14614 <listOfProducts>
14615 <speciesReference species="M_4r5au_c" stoichiometry="1.000000"/>
14616 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
14617 </listOfProducts>
14618 </reaction>
14619 <reaction id="R_PMPK" name="R_phosphomethylpyrimidine_kinase" reversible="false">
14620 <notes>
14621 <html:p>GENE_ASSOCIATION: b2103</html:p>
14622 <html:p>PROTEIN_ASSOCIATION: ThiDec</html:p>
14623 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
14624 <html:p>PROTEIN_CLASS: 2.7.4.7</html:p>
14625 </notes>
14626 <listOfReactants>
14627 <speciesReference species="M_4ampm_c" stoichiometry="1.000000"/>
14628 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
14629 </listOfReactants>
14630 <listOfProducts>
14631 <speciesReference species="M_2mahmp_c" stoichiometry="1.000000"/>
14632 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
14633 </listOfProducts>
14634 </reaction>
14635 <reaction id="R_PNTK" name="R_pantothenate_kinase" reversible="false">
14636 <notes>
14637 <html:p>GENE_ASSOCIATION: b3974</html:p>
14638 <html:p>PROTEIN_ASSOCIATION: CoaA</html:p>
14639 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
14640 <html:p>PROTEIN_CLASS: 2.7.1.33</html:p>
14641 </notes>
14642 <listOfReactants>
14643 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
14644 <speciesReference species="M_pnto_R_c" stoichiometry="1.000000"/>
14645 </listOfReactants>
14646 <listOfProducts>
14647 <speciesReference species="M_4ppan_c" stoichiometry="1.000000"/>
14648 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
14649 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14650 </listOfProducts>
14651 </reaction>
14652 <reaction id="R_PNTOt4" name="R_Pantothenate_sodium_symporter" reversible="false">
14653 <notes>
14654 <html:p>GENE_ASSOCIATION: b3258</html:p>
14655 <html:p>PROTEIN_ASSOCIATION: PanF</html:p>
14656 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
14657 <html:p>PROTEIN_CLASS: </html:p>
14658 </notes>
14659 <listOfReactants>
14660 <speciesReference species="M_na1_e" stoichiometry="1.000000"/>
14661 <speciesReference species="M_pnto_R_e" stoichiometry="1.000000"/>
14662 </listOfReactants>
14663 <listOfProducts>
14664 <speciesReference species="M_na1_c" stoichiometry="1.000000"/>
14665 <speciesReference species="M_pnto_R_c" stoichiometry="1.000000"/>
14666 </listOfProducts>
14667 </reaction>
14668 <reaction id="R_POX" name="R_pyruvate_oxidase" reversible="false">
14669 <notes>
14670 <html:p>GENE_ASSOCIATION: b0871</html:p>
14671 <html:p>PROTEIN_ASSOCIATION: PoxB</html:p>
14672 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
14673 <html:p>PROTEIN_CLASS: 1.2.2.2</html:p>
14674 </notes>
14675 <listOfReactants>
14676 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
14677 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
14678 <speciesReference species="M_q8_c" stoichiometry="1.000000"/>
14679 </listOfReactants>
14680 <listOfProducts>
14681 <speciesReference species="M_ac_c" stoichiometry="1.000000"/>
14682 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
14683 <speciesReference species="M_q8h2_c" stoichiometry="1.000000"/>
14684 </listOfProducts>
14685 </reaction>
14686 <reaction id="R_PPA" name="R_inorganic_diphosphatase" reversible="false">
14687 <notes>
14688 <html:p>GENE_ASSOCIATION: b4226</html:p>
14689 <html:p>PROTEIN_ASSOCIATION: Ppa</html:p>
14690 <html:p>SUBSYSTEM: S_Anaplerotic_reactions</html:p>
14691 <html:p>PROTEIN_CLASS: 3.6.1.1</html:p>
14692 </notes>
14693 <listOfReactants>
14694 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
14695 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
14696 </listOfReactants>
14697 <listOfProducts>
14698 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14699 <speciesReference species="M_pi_c" stoichiometry="2.000000"/>
14700 </listOfProducts>
14701 </reaction>
14702 <reaction id="R_PPAKr" name="R_Propionate_kinase" reversible="true">
14703 <notes>
14704 <html:p>GENE_ASSOCIATION: b3115</html:p>
14705 <html:p>PROTEIN_ASSOCIATION: TdcD</html:p>
14706 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
14707 <html:p>PROTEIN_CLASS: 2.7.2.1</html:p>
14708 </notes>
14709 <listOfReactants>
14710 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
14711 <speciesReference species="M_ppap_c" stoichiometry="1.000000"/>
14712 </listOfReactants>
14713 <listOfProducts>
14714 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
14715 <speciesReference species="M_ppa_c" stoichiometry="1.000000"/>
14716 </listOfProducts>
14717 </reaction>
14718 <reaction id="R_PPBNGS" name="R_porphobilinogen_synthase" reversible="false">
14719 <notes>
14720 <html:p>GENE_ASSOCIATION: b0369</html:p>
14721 <html:p>PROTEIN_ASSOCIATION: HemBec</html:p>
14722 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
14723 <html:p>PROTEIN_CLASS: 4.2.1.24</html:p>
14724 </notes>
14725 <listOfReactants>
14726 <speciesReference species="M_5aop_c" stoichiometry="2.000000"/>
14727 </listOfReactants>
14728 <listOfProducts>
14729 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14730 <speciesReference species="M_h2o_c" stoichiometry="2.000000"/>
14731 <speciesReference species="M_ppbng_c" stoichiometry="1.000000"/>
14732 </listOfProducts>
14733 </reaction>
14734 <reaction id="R_PPC" name="R_phosphoenolpyruvate_carboxylase" reversible="false">
14735 <notes>
14736 <html:p>GENE_ASSOCIATION: b3956</html:p>
14737 <html:p>PROTEIN_ASSOCIATION: Ppc</html:p>
14738 <html:p>SUBSYSTEM: S_Anaplerotic_reactions</html:p>
14739 <html:p>PROTEIN_CLASS: 4.1.1.31</html:p>
14740 </notes>
14741 <listOfReactants>
14742 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
14743 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
14744 <speciesReference species="M_pep_c" stoichiometry="1.000000"/>
14745 </listOfReactants>
14746 <listOfProducts>
14747 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14748 <speciesReference species="M_oaa_c" stoichiometry="1.000000"/>
14749 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
14750 </listOfProducts>
14751 </reaction>
14752 <reaction id="R_PPCDC" name="R_phosphopantothenoylcysteine_decarboxylase" reversible="false">
14753 <notes>
14754 <html:p>GENE_ASSOCIATION: </html:p>
14755 <html:p>PROTEIN_ASSOCIATION: </html:p>
14756 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
14757 <html:p>PROTEIN_CLASS: 4.1.1.36</html:p>
14758 </notes>
14759 <listOfReactants>
14760 <speciesReference species="M_4ppcys_c" stoichiometry="1.000000"/>
14761 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14762 </listOfReactants>
14763 <listOfProducts>
14764 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
14765 <speciesReference species="M_pan4p_c" stoichiometry="1.000000"/>
14766 </listOfProducts>
14767 </reaction>
14768 <reaction id="R_PPCK" name="R_phosphoenolpyruvate_carboxykinase" reversible="false">
14769 <notes>
14770 <html:p>GENE_ASSOCIATION: b3403</html:p>
14771 <html:p>PROTEIN_ASSOCIATION: Pck</html:p>
14772 <html:p>SUBSYSTEM: S_Anaplerotic_reactions</html:p>
14773 <html:p>PROTEIN_CLASS: 4.1.1.49</html:p>
14774 </notes>
14775 <listOfReactants>
14776 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
14777 <speciesReference species="M_oaa_c" stoichiometry="1.000000"/>
14778 </listOfReactants>
14779 <listOfProducts>
14780 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
14781 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
14782 <speciesReference species="M_pep_c" stoichiometry="1.000000"/>
14783 </listOfProducts>
14784 </reaction>
14785 <reaction id="R_PPCSCT" name="R_Propanoyl_CoA_succinate_CoA_transferase" reversible="false">
14786 <notes>
14787 <html:p>GENE_ASSOCIATION: b2920</html:p>
14788 <html:p>PROTEIN_ASSOCIATION: YgfH</html:p>
14789 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
14790 <html:p>PROTEIN_CLASS: </html:p>
14791 </notes>
14792 <listOfReactants>
14793 <speciesReference species="M_ppcoa_c" stoichiometry="1.000000"/>
14794 <speciesReference species="M_succ_c" stoichiometry="1.000000"/>
14795 </listOfReactants>
14796 <listOfProducts>
14797 <speciesReference species="M_ppa_c" stoichiometry="1.000000"/>
14798 <speciesReference species="M_succoa_c" stoichiometry="1.000000"/>
14799 </listOfProducts>
14800 </reaction>
14801 <reaction id="R_PPM" name="R_phosphopentomutase" reversible="true">
14802 <notes>
14803 <html:p>GENE_ASSOCIATION: ( b4383 or b3380 )</html:p>
14804 <html:p>PROTEIN_ASSOCIATION: ( DeoB ) or ( YhfW )</html:p>
14805 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
14806 <html:p>PROTEIN_CLASS: 5.4.2.7</html:p>
14807 </notes>
14808 <listOfReactants>
14809 <speciesReference species="M_r1p_c" stoichiometry="1.000000"/>
14810 </listOfReactants>
14811 <listOfProducts>
14812 <speciesReference species="M_r5p_c" stoichiometry="1.000000"/>
14813 </listOfProducts>
14814 </reaction>
14815 <reaction id="R_PPM2" name="R_phosphopentomutase_2__deoxyribose_" reversible="true">
14816 <notes>
14817 <html:p>GENE_ASSOCIATION: b4383</html:p>
14818 <html:p>PROTEIN_ASSOCIATION: DeoB</html:p>
14819 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
14820 <html:p>PROTEIN_CLASS: 5.4.2.7</html:p>
14821 </notes>
14822 <listOfReactants>
14823 <speciesReference species="M_2dr1p_c" stoichiometry="1.000000"/>
14824 </listOfReactants>
14825 <listOfProducts>
14826 <speciesReference species="M_2dr5p_c" stoichiometry="1.000000"/>
14827 </listOfProducts>
14828 </reaction>
14829 <reaction id="R_PPNCL2" name="R_phosphopantothenate_cysteine_ligase" reversible="false">
14830 <notes>
14831 <html:p>GENE_ASSOCIATION: </html:p>
14832 <html:p>PROTEIN_ASSOCIATION: </html:p>
14833 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
14834 <html:p>PROTEIN_CLASS: 6.3.2.5</html:p>
14835 </notes>
14836 <listOfReactants>
14837 <speciesReference species="M_4ppan_c" stoichiometry="1.000000"/>
14838 <speciesReference species="M_ctp_c" stoichiometry="1.000000"/>
14839 <speciesReference species="M_cys_L_c" stoichiometry="1.000000"/>
14840 </listOfReactants>
14841 <listOfProducts>
14842 <speciesReference species="M_4ppcys_c" stoichiometry="1.000000"/>
14843 <speciesReference species="M_cmp_c" stoichiometry="1.000000"/>
14844 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14845 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
14846 </listOfProducts>
14847 </reaction>
14848 <reaction id="R_PPND" name="R_prephenate_dehydrogenase" reversible="false">
14849 <notes>
14850 <html:p>GENE_ASSOCIATION: b2600</html:p>
14851 <html:p>PROTEIN_ASSOCIATION: TyrAec</html:p>
14852 <html:p>SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism</html:p>
14853 <html:p>PROTEIN_CLASS: 1.3.1.12</html:p>
14854 </notes>
14855 <listOfReactants>
14856 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
14857 <speciesReference species="M_pphn_c" stoichiometry="1.000000"/>
14858 </listOfReactants>
14859 <listOfProducts>
14860 <speciesReference species="M_34hpp_c" stoichiometry="1.000000"/>
14861 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
14862 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
14863 </listOfProducts>
14864 </reaction>
14865 <reaction id="R_PPNDH" name="R_prephenate_dehydratase" reversible="false">
14866 <notes>
14867 <html:p>GENE_ASSOCIATION: b2599</html:p>
14868 <html:p>PROTEIN_ASSOCIATION: PheA</html:p>
14869 <html:p>SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism</html:p>
14870 <html:p>PROTEIN_CLASS: 4.2.1.51</html:p>
14871 </notes>
14872 <listOfReactants>
14873 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14874 <speciesReference species="M_pphn_c" stoichiometry="1.000000"/>
14875 </listOfReactants>
14876 <listOfProducts>
14877 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
14878 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
14879 <speciesReference species="M_phpyr_c" stoichiometry="1.000000"/>
14880 </listOfProducts>
14881 </reaction>
14882 <reaction id="R_PPPGO" name="R_protoporphyrinogen_oxidase__aerobic_" reversible="false">
14883 <notes>
14884 <html:p>GENE_ASSOCIATION: b3850</html:p>
14885 <html:p>PROTEIN_ASSOCIATION: HemG</html:p>
14886 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
14887 <html:p>PROTEIN_CLASS: 1.3.3.4</html:p>
14888 </notes>
14889 <listOfReactants>
14890 <speciesReference species="M_o2_c" stoichiometry="1.500000"/>
14891 <speciesReference species="M_pppg9_c" stoichiometry="1.000000"/>
14892 </listOfReactants>
14893 <listOfProducts>
14894 <speciesReference species="M_h2o_c" stoichiometry="3.000000"/>
14895 <speciesReference species="M_ppp9_c" stoichiometry="1.000000"/>
14896 </listOfProducts>
14897 </reaction>
14898 <reaction id="R_PPPNDO" name="R_Phenylpropanoate_Dioxygenase" reversible="false">
14899 <notes>
14900 <html:p>GENE_ASSOCIATION: ( b2538 and b2539 and b2540 and b2542 )</html:p>
14901 <html:p>PROTEIN_ASSOCIATION: HcaCDEF</html:p>
14902 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
14903 <html:p>PROTEIN_CLASS: </html:p>
14904 </notes>
14905 <listOfReactants>
14906 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14907 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
14908 <speciesReference species="M_o2_c" stoichiometry="1.000000"/>
14909 <speciesReference species="M_pppn_c" stoichiometry="1.000000"/>
14910 </listOfReactants>
14911 <listOfProducts>
14912 <speciesReference species="M_cechddd_c" stoichiometry="1.000000"/>
14913 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
14914 </listOfProducts>
14915 </reaction>
14916 <reaction id="R_PPPNt2r" name="R_3_phenylpropionate_transport_via_proton_symport__reversible" reversible="true">
14917 <notes>
14918 <html:p>GENE_ASSOCIATION: b2536</html:p>
14919 <html:p>PROTEIN_ASSOCIATION: HcaT</html:p>
14920 <html:p>SUBSYSTEM: S_Putative_Transporters</html:p>
14921 <html:p>PROTEIN_CLASS: </html:p>
14922 </notes>
14923 <listOfReactants>
14924 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
14925 <speciesReference species="M_pppn_e" stoichiometry="1.000000"/>
14926 </listOfReactants>
14927 <listOfProducts>
14928 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14929 <speciesReference species="M_pppn_c" stoichiometry="1.000000"/>
14930 </listOfProducts>
14931 </reaction>
14932 <reaction id="R_PPS" name="R_phosphoenolpyruvate_synthase" reversible="false">
14933 <notes>
14934 <html:p>GENE_ASSOCIATION: b1702</html:p>
14935 <html:p>PROTEIN_ASSOCIATION: Ppsa</html:p>
14936 <html:p>SUBSYSTEM: S_GlycolysisGluconeogenesis</html:p>
14937 <html:p>PROTEIN_CLASS: 2.7.9.2</html:p>
14938 </notes>
14939 <listOfReactants>
14940 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
14941 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
14942 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
14943 </listOfReactants>
14944 <listOfProducts>
14945 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
14946 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
14947 <speciesReference species="M_pep_c" stoichiometry="1.000000"/>
14948 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
14949 </listOfProducts>
14950 </reaction>
14951 <reaction id="R_PPTGS" name="R_Peptidoglycan_subunit_synthesis" reversible="false">
14952 <notes>
14953 <html:p>GENE_ASSOCIATION: </html:p>
14954 <html:p>PROTEIN_ASSOCIATION: </html:p>
14955 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
14956 <html:p>PROTEIN_CLASS: </html:p>
14957 </notes>
14958 <listOfReactants>
14959 <speciesReference species="M_uaagmda_c" stoichiometry="1.000000"/>
14960 </listOfReactants>
14961 <listOfProducts>
14962 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14963 <speciesReference species="M_peptido_EC_c" stoichiometry="1.000000"/>
14964 <speciesReference species="M_udcpdp_c" stoichiometry="1.000000"/>
14965 </listOfProducts>
14966 </reaction>
14967 <reaction id="R_PRAGSr" name="R_phosphoribosylglycinamide_synthase" reversible="true">
14968 <notes>
14969 <html:p>GENE_ASSOCIATION: b4005</html:p>
14970 <html:p>PROTEIN_ASSOCIATION: PurDec</html:p>
14971 <html:p>SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis</html:p>
14972 <html:p>PROTEIN_CLASS: 6.3.4.13</html:p>
14973 </notes>
14974 <listOfReactants>
14975 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
14976 <speciesReference species="M_gly_c" stoichiometry="1.000000"/>
14977 <speciesReference species="M_pram_c" stoichiometry="1.000000"/>
14978 </listOfReactants>
14979 <listOfProducts>
14980 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
14981 <speciesReference species="M_gar_c" stoichiometry="1.000000"/>
14982 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
14983 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
14984 </listOfProducts>
14985 </reaction>
14986 <reaction id="R_PRAIS" name="R_phosphoribosylaminoimidazole_synthase" reversible="false">
14987 <notes>
14988 <html:p>GENE_ASSOCIATION: b2499</html:p>
14989 <html:p>PROTEIN_ASSOCIATION: PurM</html:p>
14990 <html:p>SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis</html:p>
14991 <html:p>PROTEIN_CLASS: 6.3.3.1</html:p>
14992 </notes>
14993 <listOfReactants>
14994 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
14995 <speciesReference species="M_fpram_c" stoichiometry="1.000000"/>
14996 </listOfReactants>
14997 <listOfProducts>
14998 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
14999 <speciesReference species="M_air_c" stoichiometry="1.000000"/>
15000 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
15001 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
15002 </listOfProducts>
15003 </reaction>
15004 <reaction id="R_PRAIi" name="R_phosphoribosylanthranilate_isomerase__irreversible_" reversible="false">
15005 <notes>
15006 <html:p>GENE_ASSOCIATION: b1262</html:p>
15007 <html:p>PROTEIN_ASSOCIATION: TrpCec</html:p>
15008 <html:p>SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism</html:p>
15009 <html:p>PROTEIN_CLASS: 5.3.1.24</html:p>
15010 </notes>
15011 <listOfReactants>
15012 <speciesReference species="M_pran_c" stoichiometry="1.000000"/>
15013 </listOfReactants>
15014 <listOfProducts>
15015 <speciesReference species="M_2cpr5p_c" stoichiometry="1.000000"/>
15016 </listOfProducts>
15017 </reaction>
15018 <reaction id="R_PRAMPC" name="R_phosphoribosyl_AMP_cyclohydrolase" reversible="false">
15019 <notes>
15020 <html:p>GENE_ASSOCIATION: b2026</html:p>
15021 <html:p>PROTEIN_ASSOCIATION: HisI</html:p>
15022 <html:p>SUBSYSTEM: S_Histidine_Metabolism</html:p>
15023 <html:p>PROTEIN_CLASS: 3.5.4.19</html:p>
15024 </notes>
15025 <listOfReactants>
15026 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
15027 <speciesReference species="M_prbamp_c" stoichiometry="1.000000"/>
15028 </listOfReactants>
15029 <listOfProducts>
15030 <speciesReference species="M_prfp_c" stoichiometry="1.000000"/>
15031 </listOfProducts>
15032 </reaction>
15033 <reaction id="R_PRASCS" name="R_phosphoribosylaminoimidazolesuccinocarboxamide_synthase" reversible="true">
15034 <notes>
15035 <html:p>GENE_ASSOCIATION: b2476</html:p>
15036 <html:p>PROTEIN_ASSOCIATION: PurC</html:p>
15037 <html:p>SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis</html:p>
15038 <html:p>PROTEIN_CLASS: 6.3.2.6</html:p>
15039 </notes>
15040 <listOfReactants>
15041 <speciesReference species="M_5aizc_c" stoichiometry="1.000000"/>
15042 <speciesReference species="M_asp_L_c" stoichiometry="1.000000"/>
15043 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
15044 </listOfReactants>
15045 <listOfProducts>
15046 <speciesReference species="M_25aics_c" stoichiometry="1.000000"/>
15047 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
15048 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
15049 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
15050 </listOfProducts>
15051 </reaction>
15052 <reaction id="R_PRATPP" name="R_phosphoribosyl_ATP_pyrophosphatase" reversible="false">
15053 <notes>
15054 <html:p>GENE_ASSOCIATION: b2026</html:p>
15055 <html:p>PROTEIN_ASSOCIATION: HisI</html:p>
15056 <html:p>SUBSYSTEM: S_Histidine_Metabolism</html:p>
15057 <html:p>PROTEIN_CLASS: 3.6.1.31</html:p>
15058 </notes>
15059 <listOfReactants>
15060 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
15061 <speciesReference species="M_prbatp_c" stoichiometry="1.000000"/>
15062 </listOfReactants>
15063 <listOfProducts>
15064 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
15065 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
15066 <speciesReference species="M_prbamp_c" stoichiometry="1.000000"/>
15067 </listOfProducts>
15068 </reaction>
15069 <reaction id="R_PRFGS" name="R_phosphoribosylformylglycinamidine_synthase" reversible="false">
15070 <notes>
15071 <html:p>GENE_ASSOCIATION: b2557</html:p>
15072 <html:p>PROTEIN_ASSOCIATION: PurL</html:p>
15073 <html:p>SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis</html:p>
15074 <html:p>PROTEIN_CLASS: 6.3.5.3</html:p>
15075 </notes>
15076 <listOfReactants>
15077 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
15078 <speciesReference species="M_fgam_c" stoichiometry="1.000000"/>
15079 <speciesReference species="M_gln_L_c" stoichiometry="1.000000"/>
15080 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
15081 </listOfReactants>
15082 <listOfProducts>
15083 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
15084 <speciesReference species="M_fpram_c" stoichiometry="1.000000"/>
15085 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
15086 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
15087 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
15088 </listOfProducts>
15089 </reaction>
15090 <reaction id="R_PRMICIi" name="R_1__5_phosphoribosyl__5__5_phosphoribosylamino_methylideneamino_imidazole_4_carboxamide_isomerase__irreversible_" reversible="false">
15091 <notes>
15092 <html:p>GENE_ASSOCIATION: b2024</html:p>
15093 <html:p>PROTEIN_ASSOCIATION: HisA</html:p>
15094 <html:p>SUBSYSTEM: S_Histidine_Metabolism</html:p>
15095 <html:p>PROTEIN_CLASS: 5.3.1.16</html:p>
15096 </notes>
15097 <listOfReactants>
15098 <speciesReference species="M_prfp_c" stoichiometry="1.000000"/>
15099 </listOfReactants>
15100 <listOfProducts>
15101 <speciesReference species="M_prlp_c" stoichiometry="1.000000"/>
15102 </listOfProducts>
15103 </reaction>
15104 <reaction id="R_PROD2" name="R_Proline_dehydrogenase" reversible="false">
15105 <notes>
15106 <html:p>GENE_ASSOCIATION: b1014</html:p>
15107 <html:p>PROTEIN_ASSOCIATION: PutAec</html:p>
15108 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
15109 <html:p>PROTEIN_CLASS: 1.5.99.8</html:p>
15110 </notes>
15111 <listOfReactants>
15112 <speciesReference species="M_fad_c" stoichiometry="1.000000"/>
15113 <speciesReference species="M_pro_L_c" stoichiometry="1.000000"/>
15114 </listOfReactants>
15115 <listOfProducts>
15116 <speciesReference species="M_1pyr5c_c" stoichiometry="1.000000"/>
15117 <speciesReference species="M_fadh2_c" stoichiometry="1.000000"/>
15118 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
15119 </listOfProducts>
15120 </reaction>
15121 <reaction id="R_PROabc" name="R_L_proline_transport_via_ABC_system" reversible="false">
15122 <notes>
15123 <html:p>GENE_ASSOCIATION: ( b2677 and b2678 and b2679 )</html:p>
15124 <html:p>PROTEIN_ASSOCIATION: ( ProVec and ProW and ProX )</html:p>
15125 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
15126 <html:p>PROTEIN_CLASS: </html:p>
15127 </notes>
15128 <listOfReactants>
15129 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
15130 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
15131 <speciesReference species="M_pro_L_e" stoichiometry="1.000000"/>
15132 </listOfReactants>
15133 <listOfProducts>
15134 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
15135 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
15136 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
15137 <speciesReference species="M_pro_L_c" stoichiometry="1.000000"/>
15138 </listOfProducts>
15139 </reaction>
15140 <reaction id="R_PROt2r" name="R_L_proline_reversible_transport_via_proton_symport" reversible="true">
15141 <notes>
15142 <html:p>GENE_ASSOCIATION: b4111</html:p>
15143 <html:p>PROTEIN_ASSOCIATION: ProPec</html:p>
15144 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
15145 <html:p>PROTEIN_CLASS: </html:p>
15146 </notes>
15147 <listOfReactants>
15148 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
15149 <speciesReference species="M_pro_L_e" stoichiometry="1.000000"/>
15150 </listOfReactants>
15151 <listOfProducts>
15152 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
15153 <speciesReference species="M_pro_L_c" stoichiometry="1.000000"/>
15154 </listOfProducts>
15155 </reaction>
15156 <reaction id="R_PROt4" name="R_NaProline_L_symporter" reversible="false">
15157 <notes>
15158 <html:p>GENE_ASSOCIATION: b1015</html:p>
15159 <html:p>PROTEIN_ASSOCIATION: PutPec</html:p>
15160 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
15161 <html:p>PROTEIN_CLASS: </html:p>
15162 </notes>
15163 <listOfReactants>
15164 <speciesReference species="M_na1_e" stoichiometry="1.000000"/>
15165 <speciesReference species="M_pro_L_e" stoichiometry="1.000000"/>
15166 </listOfReactants>
15167 <listOfProducts>
15168 <speciesReference species="M_na1_c" stoichiometry="1.000000"/>
15169 <speciesReference species="M_pro_L_c" stoichiometry="1.000000"/>
15170 </listOfProducts>
15171 </reaction>
15172 <reaction id="R_PRPPS" name="R_phosphoribosylpyrophosphate_synthetase" reversible="true">
15173 <notes>
15174 <html:p>GENE_ASSOCIATION: b1207</html:p>
15175 <html:p>PROTEIN_ASSOCIATION: PrsA</html:p>
15176 <html:p>SUBSYSTEM: S_Histidine_Metabolism</html:p>
15177 <html:p>PROTEIN_CLASS: 2.7.6.1</html:p>
15178 </notes>
15179 <listOfReactants>
15180 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
15181 <speciesReference species="M_r5p_c" stoichiometry="1.000000"/>
15182 </listOfReactants>
15183 <listOfProducts>
15184 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
15185 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
15186 <speciesReference species="M_prpp_c" stoichiometry="1.000000"/>
15187 </listOfProducts>
15188 </reaction>
15189 <reaction id="R_PSCVT" name="R_3_phosphoshikimate_1_carboxyvinyltransferase" reversible="true">
15190 <notes>
15191 <html:p>GENE_ASSOCIATION: b0908</html:p>
15192 <html:p>PROTEIN_ASSOCIATION: AroA</html:p>
15193 <html:p>SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism</html:p>
15194 <html:p>PROTEIN_CLASS: 2.5.1.19</html:p>
15195 </notes>
15196 <listOfReactants>
15197 <speciesReference species="M_pep_c" stoichiometry="1.000000"/>
15198 <speciesReference species="M_skm5p_c" stoichiometry="1.000000"/>
15199 </listOfReactants>
15200 <listOfProducts>
15201 <speciesReference species="M_3psme_c" stoichiometry="1.000000"/>
15202 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
15203 </listOfProducts>
15204 </reaction>
15205 <reaction id="R_PSD_EC" name="R_Phosphatidylserine_decarboxylase__Ecoli_" reversible="false">
15206 <notes>
15207 <html:p>GENE_ASSOCIATION: b4160</html:p>
15208 <html:p>PROTEIN_ASSOCIATION: Psd</html:p>
15209 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
15210 <html:p>PROTEIN_CLASS: 4.1.1.65</html:p>
15211 </notes>
15212 <listOfReactants>
15213 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
15214 <speciesReference species="M_ps_EC_c" stoichiometry="0.020000"/>
15215 </listOfReactants>
15216 <listOfProducts>
15217 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
15218 <speciesReference species="M_pe_EC_c" stoichiometry="0.020000"/>
15219 </listOfProducts>
15220 </reaction>
15221 <reaction id="R_PSERT" name="R_phosphoserine_transaminase" reversible="false">
15222 <notes>
15223 <html:p>GENE_ASSOCIATION: b0907</html:p>
15224 <html:p>PROTEIN_ASSOCIATION: SerC</html:p>
15225 <html:p>SUBSYSTEM: S_Glycine_and_Serine_Metabolism</html:p>
15226 <html:p>PROTEIN_CLASS: 2.6.1.52</html:p>
15227 </notes>
15228 <listOfReactants>
15229 <speciesReference species="M_3php_c" stoichiometry="1.000000"/>
15230 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
15231 </listOfReactants>
15232 <listOfProducts>
15233 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
15234 <speciesReference species="M_pser_L_c" stoichiometry="1.000000"/>
15235 </listOfProducts>
15236 </reaction>
15237 <reaction id="R_PSP_L" name="R_phosphoserine_phosphatase__L_serine_" reversible="false">
15238 <notes>
15239 <html:p>GENE_ASSOCIATION: b4388</html:p>
15240 <html:p>PROTEIN_ASSOCIATION: SerB</html:p>
15241 <html:p>SUBSYSTEM: S_Glycine_and_Serine_Metabolism</html:p>
15242 <html:p>PROTEIN_CLASS: 3.1.3.3</html:p>
15243 </notes>
15244 <listOfReactants>
15245 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
15246 <speciesReference species="M_pser_L_c" stoichiometry="1.000000"/>
15247 </listOfReactants>
15248 <listOfProducts>
15249 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
15250 <speciesReference species="M_ser_L_c" stoichiometry="1.000000"/>
15251 </listOfProducts>
15252 </reaction>
15253 <reaction id="R_PSSA_EC" name="R_Phosphatidylserine_syntase__Ecoli_" reversible="true">
15254 <notes>
15255 <html:p>GENE_ASSOCIATION: b2585</html:p>
15256 <html:p>PROTEIN_ASSOCIATION: PssA</html:p>
15257 <html:p>SUBSYSTEM: S_Membrane_Lipid_Metabolism</html:p>
15258 <html:p>PROTEIN_CLASS: 2.7.8.8</html:p>
15259 </notes>
15260 <listOfReactants>
15261 <speciesReference species="M_cdpdag_EC_c" stoichiometry="0.020000"/>
15262 <speciesReference species="M_ser_L_c" stoichiometry="1.000000"/>
15263 </listOfReactants>
15264 <listOfProducts>
15265 <speciesReference species="M_cmp_c" stoichiometry="1.000000"/>
15266 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
15267 <speciesReference species="M_ps_EC_c" stoichiometry="0.020000"/>
15268 </listOfProducts>
15269 </reaction>
15270 <reaction id="R_PTA2" name="R_Phosphate_acetyltransferase" reversible="false">
15271 <notes>
15272 <html:p>GENE_ASSOCIATION: b2297</html:p>
15273 <html:p>PROTEIN_ASSOCIATION: Pta</html:p>
15274 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
15275 <html:p>PROTEIN_CLASS: </html:p>
15276 </notes>
15277 <listOfReactants>
15278 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
15279 <speciesReference species="M_ppcoa_c" stoichiometry="1.000000"/>
15280 </listOfReactants>
15281 <listOfProducts>
15282 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
15283 <speciesReference species="M_ppap_c" stoichiometry="1.000000"/>
15284 </listOfProducts>
15285 </reaction>
15286 <reaction id="R_PTAr" name="R_phosphotransacetylase" reversible="true">
15287 <notes>
15288 <html:p>GENE_ASSOCIATION: ( b2297 or b2458 )</html:p>
15289 <html:p>PROTEIN_ASSOCIATION: ( Pta ) or ( EutD )</html:p>
15290 <html:p>SUBSYSTEM: S_Pyruvate_Metabolism</html:p>
15291 <html:p>PROTEIN_CLASS: 2.3.1.8</html:p>
15292 </notes>
15293 <listOfReactants>
15294 <speciesReference species="M_accoa_c" stoichiometry="1.000000"/>
15295 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
15296 </listOfReactants>
15297 <listOfProducts>
15298 <speciesReference species="M_actp_c" stoichiometry="1.000000"/>
15299 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
15300 </listOfProducts>
15301 </reaction>
15302 <reaction id="R_PTPATi" name="R_pantetheine_phosphate_adenylyltransferase" reversible="false">
15303 <notes>
15304 <html:p>GENE_ASSOCIATION: b3634</html:p>
15305 <html:p>PROTEIN_ASSOCIATION: CoaD</html:p>
15306 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
15307 <html:p>PROTEIN_CLASS: 2.7.7.3</html:p>
15308 </notes>
15309 <listOfReactants>
15310 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
15311 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
15312 <speciesReference species="M_pan4p_c" stoichiometry="1.000000"/>
15313 </listOfReactants>
15314 <listOfProducts>
15315 <speciesReference species="M_dpcoa_c" stoichiometry="1.000000"/>
15316 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
15317 </listOfProducts>
15318 </reaction>
15319 <reaction id="R_PTRCORNt7" name="R_putrescineornithine_antiporter" reversible="true">
15320 <notes>
15321 <html:p>GENE_ASSOCIATION: b0692</html:p>
15322 <html:p>PROTEIN_ASSOCIATION: PotEec</html:p>
15323 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
15324 <html:p>PROTEIN_CLASS: </html:p>
15325 </notes>
15326 <listOfReactants>
15327 <speciesReference species="M_orn_c" stoichiometry="1.000000"/>
15328 <speciesReference species="M_ptrc_e" stoichiometry="1.000000"/>
15329 </listOfReactants>
15330 <listOfProducts>
15331 <speciesReference species="M_ptrc_c" stoichiometry="1.000000"/>
15332 <speciesReference species="M_orn_e" stoichiometry="1.000000"/>
15333 </listOfProducts>
15334 </reaction>
15335 <reaction id="R_PTRCTA" name="R_Putrescine_Transaminase" reversible="false">
15336 <notes>
15337 <html:p>GENE_ASSOCIATION: </html:p>
15338 <html:p>PROTEIN_ASSOCIATION: </html:p>
15339 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
15340 <html:p>PROTEIN_CLASS: 2.6.1.29</html:p>
15341 </notes>
15342 <listOfReactants>
15343 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
15344 <speciesReference species="M_ptrc_c" stoichiometry="1.000000"/>
15345 </listOfReactants>
15346 <listOfProducts>
15347 <speciesReference species="M_4abutn_c" stoichiometry="1.000000"/>
15348 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
15349 </listOfProducts>
15350 </reaction>
15351 <reaction id="R_PTRCabc" name="R_putrescine_transport_via_ABC_system" reversible="false">
15352 <notes>
15353 <html:p>GENE_ASSOCIATION: ( ( b1126 and b1125 and b1124 and b1123 ) or ( b0854 and b0855 and b0856 and b0857 ) or ( b1440 and b1441 and b1442 and b1443 ) )</html:p>
15354 <html:p>PROTEIN_ASSOCIATION: ( PotA and PotB and PotC and PotDec ) or ( PotF and PotG and PotH and PotI ) or ( YdcS and YdcT and YdcU and YdcV )</html:p>
15355 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
15356 <html:p>PROTEIN_CLASS: </html:p>
15357 </notes>
15358 <listOfReactants>
15359 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
15360 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
15361 <speciesReference species="M_ptrc_e" stoichiometry="1.000000"/>
15362 </listOfReactants>
15363 <listOfProducts>
15364 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
15365 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
15366 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
15367 <speciesReference species="M_ptrc_c" stoichiometry="1.000000"/>
15368 </listOfProducts>
15369 </reaction>
15370 <reaction id="R_PTRCt2r" name="R_putrescine_transport_in_via_proton_symport__reversible" reversible="true">
15371 <notes>
15372 <html:p>GENE_ASSOCIATION: b0692</html:p>
15373 <html:p>PROTEIN_ASSOCIATION: PotEec</html:p>
15374 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
15375 <html:p>PROTEIN_CLASS: </html:p>
15376 </notes>
15377 <listOfReactants>
15378 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
15379 <speciesReference species="M_ptrc_e" stoichiometry="1.000000"/>
15380 </listOfReactants>
15381 <listOfProducts>
15382 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
15383 <speciesReference species="M_ptrc_c" stoichiometry="1.000000"/>
15384 </listOfProducts>
15385 </reaction>
15386 <reaction id="R_PUNP1" name="R_purine_nucleoside_phosphorylase__Adenosine_" reversible="true">
15387 <notes>
15388 <html:p>GENE_ASSOCIATION: ( b2407 or b4384 )</html:p>
15389 <html:p>PROTEIN_ASSOCIATION: ( XapA ) or ( DeoD )</html:p>
15390 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
15391 <html:p>PROTEIN_CLASS: 2.4.2.1</html:p>
15392 </notes>
15393 <listOfReactants>
15394 <speciesReference species="M_adn_c" stoichiometry="1.000000"/>
15395 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
15396 </listOfReactants>
15397 <listOfProducts>
15398 <speciesReference species="M_ade_c" stoichiometry="1.000000"/>
15399 <speciesReference species="M_r1p_c" stoichiometry="1.000000"/>
15400 </listOfProducts>
15401 </reaction>
15402 <reaction id="R_PUNP2" name="R_purine_nucleoside_phosphorylase__Deoxyadenosine_" reversible="true">
15403 <notes>
15404 <html:p>GENE_ASSOCIATION: ( b2407 or b4384 )</html:p>
15405 <html:p>PROTEIN_ASSOCIATION: ( XapA ) or ( DeoD )</html:p>
15406 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
15407 <html:p>PROTEIN_CLASS: 2.4.2.1</html:p>
15408 </notes>
15409 <listOfReactants>
15410 <speciesReference species="M_dad_2_c" stoichiometry="1.000000"/>
15411 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
15412 </listOfReactants>
15413 <listOfProducts>
15414 <speciesReference species="M_2dr1p_c" stoichiometry="1.000000"/>
15415 <speciesReference species="M_ade_c" stoichiometry="1.000000"/>
15416 </listOfProducts>
15417 </reaction>
15418 <reaction id="R_PUNP3" name="R_purine_nucleoside_phosphorylase__Guanosine_" reversible="true">
15419 <notes>
15420 <html:p>GENE_ASSOCIATION: ( b2407 or b4384 )</html:p>
15421 <html:p>PROTEIN_ASSOCIATION: ( XapA ) or ( DeoD )</html:p>
15422 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
15423 <html:p>PROTEIN_CLASS: 2.4.2.1</html:p>
15424 </notes>
15425 <listOfReactants>
15426 <speciesReference species="M_gsn_c" stoichiometry="1.000000"/>
15427 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
15428 </listOfReactants>
15429 <listOfProducts>
15430 <speciesReference species="M_gua_c" stoichiometry="1.000000"/>
15431 <speciesReference species="M_r1p_c" stoichiometry="1.000000"/>
15432 </listOfProducts>
15433 </reaction>
15434 <reaction id="R_PUNP4" name="R_purine_nucleoside_phosphorylase__Deoxyguanosine_" reversible="true">
15435 <notes>
15436 <html:p>GENE_ASSOCIATION: ( b2407 or b4384 )</html:p>
15437 <html:p>PROTEIN_ASSOCIATION: ( XapA ) or ( DeoD )</html:p>
15438 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
15439 <html:p>PROTEIN_CLASS: 2.4.2.1</html:p>
15440 </notes>
15441 <listOfReactants>
15442 <speciesReference species="M_dgsn_c" stoichiometry="1.000000"/>
15443 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
15444 </listOfReactants>
15445 <listOfProducts>
15446 <speciesReference species="M_2dr1p_c" stoichiometry="1.000000"/>
15447 <speciesReference species="M_gua_c" stoichiometry="1.000000"/>
15448 </listOfProducts>
15449 </reaction>
15450 <reaction id="R_PUNP5" name="R_purine_nucleoside_phosphorylase__Inosine_" reversible="true">
15451 <notes>
15452 <html:p>GENE_ASSOCIATION: ( b2407 or b4384 )</html:p>
15453 <html:p>PROTEIN_ASSOCIATION: ( XapA ) or ( DeoD )</html:p>
15454 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
15455 <html:p>PROTEIN_CLASS: 2.4.2.1</html:p>
15456 </notes>
15457 <listOfReactants>
15458 <speciesReference species="M_ins_c" stoichiometry="1.000000"/>
15459 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
15460 </listOfReactants>
15461 <listOfProducts>
15462 <speciesReference species="M_hxan_c" stoichiometry="1.000000"/>
15463 <speciesReference species="M_r1p_c" stoichiometry="1.000000"/>
15464 </listOfProducts>
15465 </reaction>
15466 <reaction id="R_PUNP6" name="R_purine_nucleoside_phosphorylase__Deoxyinosine_" reversible="true">
15467 <notes>
15468 <html:p>GENE_ASSOCIATION: ( b2407 or b4384 )</html:p>
15469 <html:p>PROTEIN_ASSOCIATION: ( XapA ) or ( DeoD )</html:p>
15470 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
15471 <html:p>PROTEIN_CLASS: 2.4.2.1</html:p>
15472 </notes>
15473 <listOfReactants>
15474 <speciesReference species="M_din_c" stoichiometry="1.000000"/>
15475 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
15476 </listOfReactants>
15477 <listOfProducts>
15478 <speciesReference species="M_2dr1p_c" stoichiometry="1.000000"/>
15479 <speciesReference species="M_hxan_c" stoichiometry="1.000000"/>
15480 </listOfProducts>
15481 </reaction>
15482 <reaction id="R_PUNP7" name="R_purine_nucleoside_phosphorylase__Xanthosine_" reversible="true">
15483 <notes>
15484 <html:p>GENE_ASSOCIATION: ( b2407 or b4384 )</html:p>
15485 <html:p>PROTEIN_ASSOCIATION: ( XapA ) or ( DeoD )</html:p>
15486 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
15487 <html:p>PROTEIN_CLASS: 2.4.2.1</html:p>
15488 </notes>
15489 <listOfReactants>
15490 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
15491 <speciesReference species="M_xtsn_c" stoichiometry="1.000000"/>
15492 </listOfReactants>
15493 <listOfProducts>
15494 <speciesReference species="M_r1p_c" stoichiometry="1.000000"/>
15495 <speciesReference species="M_xan_c" stoichiometry="1.000000"/>
15496 </listOfProducts>
15497 </reaction>
15498 <reaction id="R_PYAM5PO" name="R_pyridoxamine_5__phosphate_oxidase" reversible="false">
15499 <notes>
15500 <html:p>GENE_ASSOCIATION: b1638</html:p>
15501 <html:p>PROTEIN_ASSOCIATION: PdxHec</html:p>
15502 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
15503 <html:p>PROTEIN_CLASS: 1.4.3.5</html:p>
15504 </notes>
15505 <listOfReactants>
15506 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
15507 <speciesReference species="M_o2_c" stoichiometry="1.000000"/>
15508 <speciesReference species="M_pyam5p_c" stoichiometry="1.000000"/>
15509 </listOfReactants>
15510 <listOfProducts>
15511 <speciesReference species="M_h2o2_c" stoichiometry="1.000000"/>
15512 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
15513 <speciesReference species="M_pydx5p_c" stoichiometry="1.000000"/>
15514 </listOfProducts>
15515 </reaction>
15516 <reaction id="R_PYDAMK" name="R_pyridoxamine_kinase" reversible="false">
15517 <notes>
15518 <html:p>GENE_ASSOCIATION: b2418</html:p>
15519 <html:p>PROTEIN_ASSOCIATION: PdxK</html:p>
15520 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
15521 <html:p>PROTEIN_CLASS: 2.7.1.35</html:p>
15522 </notes>
15523 <listOfReactants>
15524 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
15525 <speciesReference species="M_pydam_c" stoichiometry="1.000000"/>
15526 </listOfReactants>
15527 <listOfProducts>
15528 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
15529 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
15530 <speciesReference species="M_pyam5p_c" stoichiometry="1.000000"/>
15531 </listOfProducts>
15532 </reaction>
15533 <reaction id="R_PYDXK" name="R_pyridoxal_kinase" reversible="false">
15534 <notes>
15535 <html:p>GENE_ASSOCIATION: ( b2418 or b1636 )</html:p>
15536 <html:p>PROTEIN_ASSOCIATION: ( PdxK ) or ( PdxYec )</html:p>
15537 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
15538 <html:p>PROTEIN_CLASS: 2.7.1.35</html:p>
15539 </notes>
15540 <listOfReactants>
15541 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
15542 <speciesReference species="M_pydx_c" stoichiometry="1.000000"/>
15543 </listOfReactants>
15544 <listOfProducts>
15545 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
15546 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
15547 <speciesReference species="M_pydx5p_c" stoichiometry="1.000000"/>
15548 </listOfProducts>
15549 </reaction>
15550 <reaction id="R_PYDXNK" name="R_pyridoxine_kinase" reversible="false">
15551 <notes>
15552 <html:p>GENE_ASSOCIATION: b2418</html:p>
15553 <html:p>PROTEIN_ASSOCIATION: PdxK</html:p>
15554 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
15555 <html:p>PROTEIN_CLASS: 2.7.1.35</html:p>
15556 </notes>
15557 <listOfReactants>
15558 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
15559 <speciesReference species="M_pydxn_c" stoichiometry="1.000000"/>
15560 </listOfReactants>
15561 <listOfProducts>
15562 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
15563 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
15564 <speciesReference species="M_pdx5p_c" stoichiometry="1.000000"/>
15565 </listOfProducts>
15566 </reaction>
15567 <reaction id="R_PYDXPP" name="R_Pyridoxal_5_phosphate_phosphatase" reversible="false">
15568 <notes>
15569 <html:p>GENE_ASSOCIATION: </html:p>
15570 <html:p>PROTEIN_ASSOCIATION: </html:p>
15571 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
15572 <html:p>PROTEIN_CLASS: </html:p>
15573 </notes>
15574 <listOfReactants>
15575 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
15576 <speciesReference species="M_pydx5p_c" stoichiometry="1.000000"/>
15577 </listOfReactants>
15578 <listOfProducts>
15579 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
15580 <speciesReference species="M_pydx_c" stoichiometry="1.000000"/>
15581 </listOfProducts>
15582 </reaction>
15583 <reaction id="R_PYK" name="R_pyruvate_kinase" reversible="false">
15584 <notes>
15585 <html:p>GENE_ASSOCIATION: ( b1854 or b1676 )</html:p>
15586 <html:p>PROTEIN_ASSOCIATION: ( Pyka ) or ( Pykf )</html:p>
15587 <html:p>SUBSYSTEM: S_GlycolysisGluconeogenesis</html:p>
15588 <html:p>PROTEIN_CLASS: 2.7.1.40</html:p>
15589 </notes>
15590 <listOfReactants>
15591 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
15592 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
15593 <speciesReference species="M_pep_c" stoichiometry="1.000000"/>
15594 </listOfReactants>
15595 <listOfProducts>
15596 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
15597 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
15598 </listOfProducts>
15599 </reaction>
15600 <reaction id="R_PYNP2r" name="R_pyrimidine_nucleoside_phosphorylase__uracil_" reversible="true">
15601 <notes>
15602 <html:p>GENE_ASSOCIATION: b3831</html:p>
15603 <html:p>PROTEIN_ASSOCIATION: Udp</html:p>
15604 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
15605 <html:p>PROTEIN_CLASS: 2.4.2.2</html:p>
15606 </notes>
15607 <listOfReactants>
15608 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
15609 <speciesReference species="M_uri_c" stoichiometry="1.000000"/>
15610 </listOfReactants>
15611 <listOfProducts>
15612 <speciesReference species="M_r1p_c" stoichiometry="1.000000"/>
15613 <speciesReference species="M_ura_c" stoichiometry="1.000000"/>
15614 </listOfProducts>
15615 </reaction>
15616 <reaction id="R_PYRt2r" name="R_pyruvate_reversible_transport_via_proton_symport" reversible="true">
15617 <notes>
15618 <html:p>GENE_ASSOCIATION: </html:p>
15619 <html:p>PROTEIN_ASSOCIATION: </html:p>
15620 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
15621 <html:p>PROTEIN_CLASS: </html:p>
15622 </notes>
15623 <listOfReactants>
15624 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
15625 <speciesReference species="M_pyr_e" stoichiometry="1.000000"/>
15626 </listOfReactants>
15627 <listOfProducts>
15628 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
15629 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
15630 </listOfProducts>
15631 </reaction>
15632 <reaction id="R_QULNS" name="R_quinolinate_synthase" reversible="false">
15633 <notes>
15634 <html:p>GENE_ASSOCIATION: b0750</html:p>
15635 <html:p>PROTEIN_ASSOCIATION: NadA</html:p>
15636 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
15637 <html:p>PROTEIN_CLASS: </html:p>
15638 </notes>
15639 <listOfReactants>
15640 <speciesReference species="M_dhap_c" stoichiometry="1.000000"/>
15641 <speciesReference species="M_iasp_c" stoichiometry="1.000000"/>
15642 </listOfReactants>
15643 <listOfProducts>
15644 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
15645 <speciesReference species="M_h2o_c" stoichiometry="2.000000"/>
15646 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
15647 <speciesReference species="M_quln_c" stoichiometry="1.000000"/>
15648 </listOfProducts>
15649 </reaction>
15650 <reaction id="R_RBFK" name="R_riboflavin_kinase" reversible="false">
15651 <notes>
15652 <html:p>GENE_ASSOCIATION: b0025</html:p>
15653 <html:p>PROTEIN_ASSOCIATION: RibFec</html:p>
15654 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
15655 <html:p>PROTEIN_CLASS: 2.7.1.26</html:p>
15656 </notes>
15657 <listOfReactants>
15658 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
15659 <speciesReference species="M_ribflv_c" stoichiometry="1.000000"/>
15660 </listOfReactants>
15661 <listOfProducts>
15662 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
15663 <speciesReference species="M_fmn_c" stoichiometry="1.000000"/>
15664 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
15665 </listOfProducts>
15666 </reaction>
15667 <reaction id="R_RBFSa" name="R_riboflavin_synthase" reversible="false">
15668 <notes>
15669 <html:p>GENE_ASSOCIATION: b1662</html:p>
15670 <html:p>PROTEIN_ASSOCIATION: RibCec</html:p>
15671 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
15672 <html:p>PROTEIN_CLASS: 2.5.1.9</html:p>
15673 </notes>
15674 <listOfReactants>
15675 <speciesReference species="M_4r5au_c" stoichiometry="1.000000"/>
15676 <speciesReference species="M_db4p_c" stoichiometry="1.000000"/>
15677 </listOfReactants>
15678 <listOfProducts>
15679 <speciesReference species="M_dmlz_c" stoichiometry="1.000000"/>
15680 <speciesReference species="M_h2o_c" stoichiometry="2.000000"/>
15681 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
15682 </listOfProducts>
15683 </reaction>
15684 <reaction id="R_RBFSb" name="R_riboflavin_synthase" reversible="false">
15685 <notes>
15686 <html:p>GENE_ASSOCIATION: b0415</html:p>
15687 <html:p>PROTEIN_ASSOCIATION: RibH</html:p>
15688 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
15689 <html:p>PROTEIN_CLASS: 2.5.1.9</html:p>
15690 </notes>
15691 <listOfReactants>
15692 <speciesReference species="M_dmlz_c" stoichiometry="2.000000"/>
15693 </listOfReactants>
15694 <listOfProducts>
15695 <speciesReference species="M_4r5au_c" stoichiometry="1.000000"/>
15696 <speciesReference species="M_ribflv_c" stoichiometry="1.000000"/>
15697 </listOfProducts>
15698 </reaction>
15699 <reaction id="R_RBK" name="R_ribokinase" reversible="false">
15700 <notes>
15701 <html:p>GENE_ASSOCIATION: b3752</html:p>
15702 <html:p>PROTEIN_ASSOCIATION: RbsK</html:p>
15703 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
15704 <html:p>PROTEIN_CLASS: 2.7.1.15</html:p>
15705 </notes>
15706 <listOfReactants>
15707 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
15708 <speciesReference species="M_rib_D_c" stoichiometry="1.000000"/>
15709 </listOfReactants>
15710 <listOfProducts>
15711 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
15712 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
15713 <speciesReference species="M_r5p_c" stoichiometry="1.000000"/>
15714 </listOfProducts>
15715 </reaction>
15716 <reaction id="R_RBK_L1" name="R_L_ribulokinase__L_ribulose_" reversible="false">
15717 <notes>
15718 <html:p>GENE_ASSOCIATION: b0063</html:p>
15719 <html:p>PROTEIN_ASSOCIATION: AraB</html:p>
15720 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
15721 <html:p>PROTEIN_CLASS: 2.7.1.16</html:p>
15722 </notes>
15723 <listOfReactants>
15724 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
15725 <speciesReference species="M_rbl_L_c" stoichiometry="1.000000"/>
15726 </listOfReactants>
15727 <listOfProducts>
15728 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
15729 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
15730 <speciesReference species="M_ru5p_L_c" stoichiometry="1.000000"/>
15731 </listOfProducts>
15732 </reaction>
15733 <reaction id="R_RBP4E" name="R_L_ribulose_phosphate_4_epimerase" reversible="true">
15734 <notes>
15735 <html:p>GENE_ASSOCIATION: ( b0061 or b3583 or b4198 )</html:p>
15736 <html:p>PROTEIN_ASSOCIATION: ( AraD ) or ( SgbE ) or ( SgaE )</html:p>
15737 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
15738 <html:p>PROTEIN_CLASS: 5.1.3.4</html:p>
15739 </notes>
15740 <listOfReactants>
15741 <speciesReference species="M_ru5p_L_c" stoichiometry="1.000000"/>
15742 </listOfReactants>
15743 <listOfProducts>
15744 <speciesReference species="M_xu5p_D_c" stoichiometry="1.000000"/>
15745 </listOfProducts>
15746 </reaction>
15747 <reaction id="R_RHCCE" name="R_S_ribosylhomocysteine_cleavage_enzyme" reversible="false">
15748 <notes>
15749 <html:p>GENE_ASSOCIATION: b2687</html:p>
15750 <html:p>PROTEIN_ASSOCIATION: LuxS</html:p>
15751 <html:p>SUBSYSTEM: S_Methionine_Metabolism</html:p>
15752 <html:p>PROTEIN_CLASS: </html:p>
15753 </notes>
15754 <listOfReactants>
15755 <speciesReference species="M_rhcys_c" stoichiometry="1.000000"/>
15756 </listOfReactants>
15757 <listOfProducts>
15758 <speciesReference species="M_dhptd_c" stoichiometry="1.000000"/>
15759 <speciesReference species="M_hcys_L_c" stoichiometry="1.000000"/>
15760 </listOfProducts>
15761 </reaction>
15762 <reaction id="R_RIBabc" name="R_D_ribose_transport_via_ABC_system" reversible="false">
15763 <notes>
15764 <html:p>GENE_ASSOCIATION: ( ( b4231 and b4227 and b4228 and b4229 and b4230 ) or ( b3749 and b3751 and b3750 and b3748 ) )</html:p>
15765 <html:p>PROTEIN_ASSOCIATION: ( YjfF and YtfQ and YtfR and YtfS and YtfT ) or ( RbsA and RbsB and RbsC and RbsDec )</html:p>
15766 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
15767 <html:p>PROTEIN_CLASS: </html:p>
15768 </notes>
15769 <listOfReactants>
15770 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
15771 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
15772 <speciesReference species="M_rib_D_e" stoichiometry="1.000000"/>
15773 </listOfReactants>
15774 <listOfProducts>
15775 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
15776 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
15777 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
15778 <speciesReference species="M_rib_D_c" stoichiometry="1.000000"/>
15779 </listOfProducts>
15780 </reaction>
15781 <reaction id="R_RMI" name="R_L_rhamnose_isomerase" reversible="true">
15782 <notes>
15783 <html:p>GENE_ASSOCIATION: b3903</html:p>
15784 <html:p>PROTEIN_ASSOCIATION: RhaA</html:p>
15785 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
15786 <html:p>PROTEIN_CLASS: 5.3.1.14</html:p>
15787 </notes>
15788 <listOfReactants>
15789 <speciesReference species="M_rmn_c" stoichiometry="1.000000"/>
15790 </listOfReactants>
15791 <listOfProducts>
15792 <speciesReference species="M_rml_c" stoichiometry="1.000000"/>
15793 </listOfProducts>
15794 </reaction>
15795 <reaction id="R_RMK" name="R_rhamnulokinase" reversible="false">
15796 <notes>
15797 <html:p>GENE_ASSOCIATION: b3904</html:p>
15798 <html:p>PROTEIN_ASSOCIATION: RhaB</html:p>
15799 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
15800 <html:p>PROTEIN_CLASS: 2.7.1.5</html:p>
15801 </notes>
15802 <listOfReactants>
15803 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
15804 <speciesReference species="M_rml_c" stoichiometry="1.000000"/>
15805 </listOfReactants>
15806 <listOfProducts>
15807 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
15808 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
15809 <speciesReference species="M_rml1p_c" stoichiometry="1.000000"/>
15810 </listOfProducts>
15811 </reaction>
15812 <reaction id="R_RMNt" name="R_L_rhamnose_transport_via_proton_symport" reversible="false">
15813 <notes>
15814 <html:p>GENE_ASSOCIATION: b3907</html:p>
15815 <html:p>PROTEIN_ASSOCIATION: RhaT</html:p>
15816 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
15817 <html:p>PROTEIN_CLASS: </html:p>
15818 </notes>
15819 <listOfReactants>
15820 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
15821 <speciesReference species="M_rmn_e" stoichiometry="1.000000"/>
15822 </listOfReactants>
15823 <listOfProducts>
15824 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
15825 <speciesReference species="M_rmn_c" stoichiometry="1.000000"/>
15826 </listOfProducts>
15827 </reaction>
15828 <reaction id="R_RMPA" name="R_Rhamnulose_1_phosphate_aldolase" reversible="true">
15829 <notes>
15830 <html:p>GENE_ASSOCIATION: b3902</html:p>
15831 <html:p>PROTEIN_ASSOCIATION: RhaD</html:p>
15832 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
15833 <html:p>PROTEIN_CLASS: 4.1.2.19</html:p>
15834 </notes>
15835 <listOfReactants>
15836 <speciesReference species="M_rml1p_c" stoichiometry="1.000000"/>
15837 </listOfReactants>
15838 <listOfProducts>
15839 <speciesReference species="M_dhap_c" stoichiometry="1.000000"/>
15840 <speciesReference species="M_lald_L_c" stoichiometry="1.000000"/>
15841 </listOfProducts>
15842 </reaction>
15843 <reaction id="R_RNDR1" name="R_ribonucleoside_diphosphate_reductase__ADP_" reversible="false">
15844 <notes>
15845 <html:p>GENE_ASSOCIATION: ( b2234 and b2235 )</html:p>
15846 <html:p>PROTEIN_ASSOCIATION: NrdA</html:p>
15847 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
15848 <html:p>PROTEIN_CLASS: 1.17.4.1</html:p>
15849 </notes>
15850 <listOfReactants>
15851 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
15852 <speciesReference species="M_trdrd_c" stoichiometry="1.000000"/>
15853 </listOfReactants>
15854 <listOfProducts>
15855 <speciesReference species="M_dadp_c" stoichiometry="1.000000"/>
15856 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
15857 <speciesReference species="M_trdox_c" stoichiometry="1.000000"/>
15858 </listOfProducts>
15859 </reaction>
15860 <reaction id="R_RNDR2" name="R_ribonucleoside_diphosphate_reductase__GDP_" reversible="false">
15861 <notes>
15862 <html:p>GENE_ASSOCIATION: ( b2234 and b2235 )</html:p>
15863 <html:p>PROTEIN_ASSOCIATION: NrdA</html:p>
15864 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
15865 <html:p>PROTEIN_CLASS: 1.17.4.1</html:p>
15866 </notes>
15867 <listOfReactants>
15868 <speciesReference species="M_gdp_c" stoichiometry="1.000000"/>
15869 <speciesReference species="M_trdrd_c" stoichiometry="1.000000"/>
15870 </listOfReactants>
15871 <listOfProducts>
15872 <speciesReference species="M_dgdp_c" stoichiometry="1.000000"/>
15873 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
15874 <speciesReference species="M_trdox_c" stoichiometry="1.000000"/>
15875 </listOfProducts>
15876 </reaction>
15877 <reaction id="R_RNDR3" name="R_ribonucleoside_diphosphate_reductase__CDP_" reversible="false">
15878 <notes>
15879 <html:p>GENE_ASSOCIATION: ( ( b2234 and b2235 ) or ( b2675 and b2676 ) )</html:p>
15880 <html:p>PROTEIN_ASSOCIATION: ( NrdA ) or ( NrdE )</html:p>
15881 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
15882 <html:p>PROTEIN_CLASS: 1.17.4.1</html:p>
15883 </notes>
15884 <listOfReactants>
15885 <speciesReference species="M_cdp_c" stoichiometry="1.000000"/>
15886 <speciesReference species="M_trdrd_c" stoichiometry="1.000000"/>
15887 </listOfReactants>
15888 <listOfProducts>
15889 <speciesReference species="M_dcdp_c" stoichiometry="1.000000"/>
15890 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
15891 <speciesReference species="M_trdox_c" stoichiometry="1.000000"/>
15892 </listOfProducts>
15893 </reaction>
15894 <reaction id="R_RNDR4" name="R_ribonucleoside_diphosphate_reductase__UDP_" reversible="false">
15895 <notes>
15896 <html:p>GENE_ASSOCIATION: ( b2234 and b2235 )</html:p>
15897 <html:p>PROTEIN_ASSOCIATION: NrdA</html:p>
15898 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
15899 <html:p>PROTEIN_CLASS: 1.17.4.1</html:p>
15900 </notes>
15901 <listOfReactants>
15902 <speciesReference species="M_trdrd_c" stoichiometry="1.000000"/>
15903 <speciesReference species="M_udp_c" stoichiometry="1.000000"/>
15904 </listOfReactants>
15905 <listOfProducts>
15906 <speciesReference species="M_dudp_c" stoichiometry="1.000000"/>
15907 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
15908 <speciesReference species="M_trdox_c" stoichiometry="1.000000"/>
15909 </listOfProducts>
15910 </reaction>
15911 <reaction id="R_RNTR1" name="R_ribonucleoside_triphosphate_reductase__ATP_" reversible="false">
15912 <notes>
15913 <html:p>GENE_ASSOCIATION: b4238</html:p>
15914 <html:p>PROTEIN_ASSOCIATION: NrdD</html:p>
15915 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
15916 <html:p>PROTEIN_CLASS: 1.17.4.2</html:p>
15917 </notes>
15918 <listOfReactants>
15919 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
15920 <speciesReference species="M_trdrd_c" stoichiometry="1.000000"/>
15921 </listOfReactants>
15922 <listOfProducts>
15923 <speciesReference species="M_datp_c" stoichiometry="1.000000"/>
15924 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
15925 <speciesReference species="M_trdox_c" stoichiometry="1.000000"/>
15926 </listOfProducts>
15927 </reaction>
15928 <reaction id="R_RNTR2" name="R_ribonucleoside_triphosphate_reductase__GTP_" reversible="false">
15929 <notes>
15930 <html:p>GENE_ASSOCIATION: b4238</html:p>
15931 <html:p>PROTEIN_ASSOCIATION: NrdD</html:p>
15932 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
15933 <html:p>PROTEIN_CLASS: 1.17.4.2</html:p>
15934 </notes>
15935 <listOfReactants>
15936 <speciesReference species="M_gtp_c" stoichiometry="1.000000"/>
15937 <speciesReference species="M_trdrd_c" stoichiometry="1.000000"/>
15938 </listOfReactants>
15939 <listOfProducts>
15940 <speciesReference species="M_dgtp_c" stoichiometry="1.000000"/>
15941 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
15942 <speciesReference species="M_trdox_c" stoichiometry="1.000000"/>
15943 </listOfProducts>
15944 </reaction>
15945 <reaction id="R_RNTR3" name="R_ribonucleoside_triphosphate_reductase__CTP_" reversible="false">
15946 <notes>
15947 <html:p>GENE_ASSOCIATION: b4238</html:p>
15948 <html:p>PROTEIN_ASSOCIATION: NrdD</html:p>
15949 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
15950 <html:p>PROTEIN_CLASS: 1.17.4.2</html:p>
15951 </notes>
15952 <listOfReactants>
15953 <speciesReference species="M_ctp_c" stoichiometry="1.000000"/>
15954 <speciesReference species="M_trdrd_c" stoichiometry="1.000000"/>
15955 </listOfReactants>
15956 <listOfProducts>
15957 <speciesReference species="M_dctp_c" stoichiometry="1.000000"/>
15958 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
15959 <speciesReference species="M_trdox_c" stoichiometry="1.000000"/>
15960 </listOfProducts>
15961 </reaction>
15962 <reaction id="R_RNTR4" name="R_ribonucleoside_triphosphate_reductase__UTP_" reversible="false">
15963 <notes>
15964 <html:p>GENE_ASSOCIATION: b4238</html:p>
15965 <html:p>PROTEIN_ASSOCIATION: NrdD</html:p>
15966 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
15967 <html:p>PROTEIN_CLASS: 1.17.4.2</html:p>
15968 </notes>
15969 <listOfReactants>
15970 <speciesReference species="M_trdrd_c" stoichiometry="1.000000"/>
15971 <speciesReference species="M_utp_c" stoichiometry="1.000000"/>
15972 </listOfReactants>
15973 <listOfProducts>
15974 <speciesReference species="M_dutp_c" stoichiometry="1.000000"/>
15975 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
15976 <speciesReference species="M_trdox_c" stoichiometry="1.000000"/>
15977 </listOfProducts>
15978 </reaction>
15979 <reaction id="R_RPE" name="R_ribulose_5_phosphate_3_epimerase" reversible="true">
15980 <notes>
15981 <html:p>GENE_ASSOCIATION: ( b3386 or b4301 )</html:p>
15982 <html:p>PROTEIN_ASSOCIATION: ( Rpeec ) or ( SgcE )</html:p>
15983 <html:p>SUBSYSTEM: S_Pentose_Phosphate_Pathway</html:p>
15984 <html:p>PROTEIN_CLASS: 5.1.3.1</html:p>
15985 </notes>
15986 <listOfReactants>
15987 <speciesReference species="M_ru5p_D_c" stoichiometry="1.000000"/>
15988 </listOfReactants>
15989 <listOfProducts>
15990 <speciesReference species="M_xu5p_D_c" stoichiometry="1.000000"/>
15991 </listOfProducts>
15992 </reaction>
15993 <reaction id="R_RPI" name="R_ribose_5_phosphate_isomerase" reversible="true">
15994 <notes>
15995 <html:p>GENE_ASSOCIATION: ( b2914 or b4090 )</html:p>
15996 <html:p>PROTEIN_ASSOCIATION: ( RpiA ) or ( RpiB )</html:p>
15997 <html:p>SUBSYSTEM: S_Pentose_Phosphate_Pathway</html:p>
15998 <html:p>PROTEIN_CLASS: 5.3.1.6</html:p>
15999 </notes>
16000 <listOfReactants>
16001 <speciesReference species="M_r5p_c" stoichiometry="1.000000"/>
16002 </listOfReactants>
16003 <listOfProducts>
16004 <speciesReference species="M_ru5p_D_c" stoichiometry="1.000000"/>
16005 </listOfProducts>
16006 </reaction>
16007 <reaction id="R_RZ5PP" name="R_alpha_ribazole_5_phosphate_phosphatase" reversible="false">
16008 <notes>
16009 <html:p>GENE_ASSOCIATION: b0638</html:p>
16010 <html:p>PROTEIN_ASSOCIATION: PhpB</html:p>
16011 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
16012 <html:p>PROTEIN_CLASS: </html:p>
16013 </notes>
16014 <listOfReactants>
16015 <speciesReference species="M_5prdmbz_c" stoichiometry="1.000000"/>
16016 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
16017 </listOfReactants>
16018 <listOfProducts>
16019 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
16020 <speciesReference species="M_rdmbzi_c" stoichiometry="1.000000"/>
16021 </listOfProducts>
16022 </reaction>
16023 <reaction id="R_S7PI" name="R_sedoheptulose_7_phosphate_isomerase" reversible="false">
16024 <notes>
16025 <html:p>GENE_ASSOCIATION: b0222</html:p>
16026 <html:p>PROTEIN_ASSOCIATION: GmhA</html:p>
16027 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
16028 <html:p>PROTEIN_CLASS: </html:p>
16029 </notes>
16030 <listOfReactants>
16031 <speciesReference species="M_s7p_c" stoichiometry="1.000000"/>
16032 </listOfReactants>
16033 <listOfProducts>
16034 <speciesReference species="M_gmhep7p_c" stoichiometry="1.000000"/>
16035 </listOfProducts>
16036 </reaction>
16037 <reaction id="R_SADH" name="R_Succinylarginine_dihydrolase" reversible="false">
16038 <notes>
16039 <html:p>GENE_ASSOCIATION: b1748</html:p>
16040 <html:p>PROTEIN_ASSOCIATION: AstC</html:p>
16041 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
16042 <html:p>PROTEIN_CLASS: 2.6.1.69</html:p>
16043 </notes>
16044 <listOfReactants>
16045 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
16046 <speciesReference species="M_h2o_c" stoichiometry="2.000000"/>
16047 <speciesReference species="M_sucarg_c" stoichiometry="1.000000"/>
16048 </listOfReactants>
16049 <listOfProducts>
16050 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
16051 <speciesReference species="M_nh4_c" stoichiometry="2.000000"/>
16052 <speciesReference species="M_sucorn_c" stoichiometry="1.000000"/>
16053 </listOfProducts>
16054 </reaction>
16055 <reaction id="R_SADT2" name="R_Sulfate_adenyltransferase" reversible="false">
16056 <notes>
16057 <html:p>GENE_ASSOCIATION: ( b2751 and b2752 )</html:p>
16058 <html:p>PROTEIN_ASSOCIATION: CysD</html:p>
16059 <html:p>SUBSYSTEM: S_Cysteine_Metabolism</html:p>
16060 <html:p>PROTEIN_CLASS: </html:p>
16061 </notes>
16062 <listOfReactants>
16063 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
16064 <speciesReference species="M_gtp_c" stoichiometry="1.000000"/>
16065 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
16066 <speciesReference species="M_so4_c" stoichiometry="1.000000"/>
16067 </listOfReactants>
16068 <listOfProducts>
16069 <speciesReference species="M_aps_c" stoichiometry="1.000000"/>
16070 <speciesReference species="M_gdp_c" stoichiometry="1.000000"/>
16071 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
16072 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
16073 </listOfProducts>
16074 </reaction>
16075 <reaction id="R_SBTPD" name="R_sorbitol_6_phosphate_dehydrogenase" reversible="true">
16076 <notes>
16077 <html:p>GENE_ASSOCIATION: b2705</html:p>
16078 <html:p>PROTEIN_ASSOCIATION: SrlD</html:p>
16079 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
16080 <html:p>PROTEIN_CLASS: 1.1.1.140</html:p>
16081 </notes>
16082 <listOfReactants>
16083 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
16084 <speciesReference species="M_sbt6p_c" stoichiometry="1.000000"/>
16085 </listOfReactants>
16086 <listOfProducts>
16087 <speciesReference species="M_f6p_c" stoichiometry="1.000000"/>
16088 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
16089 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
16090 </listOfProducts>
16091 </reaction>
16092 <reaction id="R_SBTpts" name="R_D_sorbitol_transport_via_PEPPyr_PTS" reversible="false">
16093 <notes>
16094 <html:p>GENE_ASSOCIATION: ( b2415 and b2416 and b2702 and b2704 and b2703 )</html:p>
16095 <html:p>PROTEIN_ASSOCIATION: ( PtsH and PtsI and SrlA and SrlB and SrlE )</html:p>
16096 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
16097 <html:p>PROTEIN_CLASS: </html:p>
16098 </notes>
16099 <listOfReactants>
16100 <speciesReference species="M_pep_c" stoichiometry="1.000000"/>
16101 <speciesReference species="M_sbt_D_e" stoichiometry="1.000000"/>
16102 </listOfReactants>
16103 <listOfProducts>
16104 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
16105 <speciesReference species="M_sbt6p_c" stoichiometry="1.000000"/>
16106 </listOfProducts>
16107 </reaction>
16108 <reaction id="R_SDPDS" name="R_succinyl_diaminopimelate_desuccinylase" reversible="false">
16109 <notes>
16110 <html:p>GENE_ASSOCIATION: b2472</html:p>
16111 <html:p>PROTEIN_ASSOCIATION: DapE</html:p>
16112 <html:p>SUBSYSTEM: S_Threonine_and_Lysine_Metabolism</html:p>
16113 <html:p>PROTEIN_CLASS: 3.5.1.18</html:p>
16114 </notes>
16115 <listOfReactants>
16116 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
16117 <speciesReference species="M_sl26da_c" stoichiometry="1.000000"/>
16118 </listOfReactants>
16119 <listOfProducts>
16120 <speciesReference species="M_26dap_LL_c" stoichiometry="1.000000"/>
16121 <speciesReference species="M_succ_c" stoichiometry="1.000000"/>
16122 </listOfProducts>
16123 </reaction>
16124 <reaction id="R_SDPTA" name="R_succinyldiaminopimelate_transaminase" reversible="true">
16125 <notes>
16126 <html:p>GENE_ASSOCIATION: </html:p>
16127 <html:p>PROTEIN_ASSOCIATION: </html:p>
16128 <html:p>SUBSYSTEM: S_Threonine_and_Lysine_Metabolism</html:p>
16129 <html:p>PROTEIN_CLASS: 2.6.1.17</html:p>
16130 </notes>
16131 <listOfReactants>
16132 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
16133 <speciesReference species="M_sl26da_c" stoichiometry="1.000000"/>
16134 </listOfReactants>
16135 <listOfProducts>
16136 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
16137 <speciesReference species="M_sl2a6o_c" stoichiometry="1.000000"/>
16138 </listOfProducts>
16139 </reaction>
16140 <reaction id="R_SELNPS" name="R_Selenophosphate_synthase" reversible="false">
16141 <notes>
16142 <html:p>GENE_ASSOCIATION: b1764</html:p>
16143 <html:p>PROTEIN_ASSOCIATION: SelD</html:p>
16144 <html:p>SUBSYSTEM: S_Unassigned</html:p>
16145 <html:p>PROTEIN_CLASS: 2.7.9.3</html:p>
16146 </notes>
16147 <listOfReactants>
16148 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
16149 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
16150 <speciesReference species="M_seln_c" stoichiometry="1.000000"/>
16151 </listOfReactants>
16152 <listOfProducts>
16153 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
16154 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
16155 <speciesReference species="M_selnp_c" stoichiometry="1.000000"/>
16156 </listOfProducts>
16157 </reaction>
16158 <reaction id="R_SERASr" name="R__L_seryl_adenylate_synthase" reversible="true">
16159 <notes>
16160 <html:p>GENE_ASSOCIATION: b0586</html:p>
16161 <html:p>PROTEIN_ASSOCIATION: EntF</html:p>
16162 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
16163 <html:p>PROTEIN_CLASS: </html:p>
16164 </notes>
16165 <listOfReactants>
16166 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
16167 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
16168 <speciesReference species="M_ser_L_c" stoichiometry="1.000000"/>
16169 </listOfReactants>
16170 <listOfProducts>
16171 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
16172 <speciesReference species="M_seramp_c" stoichiometry="1.000000"/>
16173 </listOfProducts>
16174 </reaction>
16175 <reaction id="R_SERAT" name="R_serine_O_acetyltransferase" reversible="true">
16176 <notes>
16177 <html:p>GENE_ASSOCIATION: b3607</html:p>
16178 <html:p>PROTEIN_ASSOCIATION: CysE</html:p>
16179 <html:p>SUBSYSTEM: S_Cysteine_Metabolism</html:p>
16180 <html:p>PROTEIN_CLASS: 2.3.1.30</html:p>
16181 </notes>
16182 <listOfReactants>
16183 <speciesReference species="M_accoa_c" stoichiometry="1.000000"/>
16184 <speciesReference species="M_ser_L_c" stoichiometry="1.000000"/>
16185 </listOfReactants>
16186 <listOfProducts>
16187 <speciesReference species="M_acser_c" stoichiometry="1.000000"/>
16188 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
16189 </listOfProducts>
16190 </reaction>
16191 <reaction id="R_SERD_D" name="R_D_serine_deaminase" reversible="false">
16192 <notes>
16193 <html:p>GENE_ASSOCIATION: b2366</html:p>
16194 <html:p>PROTEIN_ASSOCIATION: DsdA</html:p>
16195 <html:p>SUBSYSTEM: S_Glycine_and_Serine_Metabolism</html:p>
16196 <html:p>PROTEIN_CLASS: </html:p>
16197 </notes>
16198 <listOfReactants>
16199 <speciesReference species="M_ser_D_c" stoichiometry="1.000000"/>
16200 </listOfReactants>
16201 <listOfProducts>
16202 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
16203 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
16204 </listOfProducts>
16205 </reaction>
16206 <reaction id="R_SERD_L" name="R_L_serine_deaminase" reversible="false">
16207 <notes>
16208 <html:p>GENE_ASSOCIATION: ( b1814 or b2797 or b3708 or ( b3111 and b3112 ) )</html:p>
16209 <html:p>PROTEIN_ASSOCIATION: ( SdaAec ) or ( SdaB ) or ( TnaA ) or ( TdcG )</html:p>
16210 <html:p>SUBSYSTEM: S_Glycine_and_Serine_Metabolism</html:p>
16211 <html:p>PROTEIN_CLASS: 4.3.1.17</html:p>
16212 </notes>
16213 <listOfReactants>
16214 <speciesReference species="M_ser_L_c" stoichiometry="1.000000"/>
16215 </listOfReactants>
16216 <listOfProducts>
16217 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
16218 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
16219 </listOfProducts>
16220 </reaction>
16221 <reaction id="R_SERt2r" name="R_L_serine_reversible_transport_via_proton_symport" reversible="true">
16222 <notes>
16223 <html:p>GENE_ASSOCIATION: ( b2796 or b3116 )</html:p>
16224 <html:p>PROTEIN_ASSOCIATION: ( SdaC ) or ( TdcC )</html:p>
16225 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
16226 <html:p>PROTEIN_CLASS: </html:p>
16227 </notes>
16228 <listOfReactants>
16229 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
16230 <speciesReference species="M_ser_L_e" stoichiometry="1.000000"/>
16231 </listOfReactants>
16232 <listOfProducts>
16233 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
16234 <speciesReference species="M_ser_L_c" stoichiometry="1.000000"/>
16235 </listOfProducts>
16236 </reaction>
16237 <reaction id="R_SERt4" name="R_L_serine_via_sodium_symport" reversible="false">
16238 <notes>
16239 <html:p>GENE_ASSOCIATION: b3089</html:p>
16240 <html:p>PROTEIN_ASSOCIATION: SstT</html:p>
16241 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
16242 <html:p>PROTEIN_CLASS: </html:p>
16243 </notes>
16244 <listOfReactants>
16245 <speciesReference species="M_na1_e" stoichiometry="1.000000"/>
16246 <speciesReference species="M_ser_L_e" stoichiometry="1.000000"/>
16247 </listOfReactants>
16248 <listOfProducts>
16249 <speciesReference species="M_na1_c" stoichiometry="1.000000"/>
16250 <speciesReference species="M_ser_L_c" stoichiometry="1.000000"/>
16251 </listOfProducts>
16252 </reaction>
16253 <reaction id="R_SGDS" name="R_Succinylglutamate_desuccinylase" reversible="false">
16254 <notes>
16255 <html:p>GENE_ASSOCIATION: b1744</html:p>
16256 <html:p>PROTEIN_ASSOCIATION: AstE</html:p>
16257 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
16258 <html:p>PROTEIN_CLASS: </html:p>
16259 </notes>
16260 <listOfReactants>
16261 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
16262 <speciesReference species="M_sucglu_c" stoichiometry="1.000000"/>
16263 </listOfReactants>
16264 <listOfProducts>
16265 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
16266 <speciesReference species="M_succ_c" stoichiometry="1.000000"/>
16267 </listOfProducts>
16268 </reaction>
16269 <reaction id="R_SGSAD" name="R_Succinylglutamic_semialdehyde_dehydrogenase" reversible="false">
16270 <notes>
16271 <html:p>GENE_ASSOCIATION: b1746</html:p>
16272 <html:p>PROTEIN_ASSOCIATION: AstD</html:p>
16273 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
16274 <html:p>PROTEIN_CLASS: </html:p>
16275 </notes>
16276 <listOfReactants>
16277 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
16278 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
16279 <speciesReference species="M_sucgsa_c" stoichiometry="1.000000"/>
16280 </listOfReactants>
16281 <listOfProducts>
16282 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
16283 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
16284 <speciesReference species="M_sucglu_c" stoichiometry="1.000000"/>
16285 </listOfProducts>
16286 </reaction>
16287 <reaction id="R_SHCHCS2" name="R_2_succinyl_6_hydroxy_2_4_cyclohexadiene_1_carboxylate_synthase" reversible="false">
16288 <notes>
16289 <html:p>GENE_ASSOCIATION: b2264</html:p>
16290 <html:p>PROTEIN_ASSOCIATION: MenD</html:p>
16291 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
16292 <html:p>PROTEIN_CLASS: </html:p>
16293 </notes>
16294 <listOfReactants>
16295 <speciesReference species="M_ichor_c" stoichiometry="1.000000"/>
16296 <speciesReference species="M_ssaltpp_c" stoichiometry="1.000000"/>
16297 </listOfReactants>
16298 <listOfProducts>
16299 <speciesReference species="M_2shchc_c" stoichiometry="1.000000"/>
16300 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
16301 <speciesReference species="M_thmpp_c" stoichiometry="1.000000"/>
16302 </listOfProducts>
16303 </reaction>
16304 <reaction id="R_SHCHD2" name="R_sirohydrochlorin_dehydrogenase__NAD_" reversible="false">
16305 <notes>
16306 <html:p>GENE_ASSOCIATION: b3368</html:p>
16307 <html:p>PROTEIN_ASSOCIATION: CysG</html:p>
16308 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
16309 <html:p>PROTEIN_CLASS: </html:p>
16310 </notes>
16311 <listOfReactants>
16312 <speciesReference species="M_dscl_c" stoichiometry="1.000000"/>
16313 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
16314 </listOfReactants>
16315 <listOfProducts>
16316 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
16317 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
16318 <speciesReference species="M_scl_c" stoichiometry="1.000000"/>
16319 </listOfProducts>
16320 </reaction>
16321 <reaction id="R_SHCHF" name="R_sirohydrochlorin_ferrochetalase" reversible="false">
16322 <notes>
16323 <html:p>GENE_ASSOCIATION: b3368</html:p>
16324 <html:p>PROTEIN_ASSOCIATION: CysG</html:p>
16325 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
16326 <html:p>PROTEIN_CLASS: </html:p>
16327 </notes>
16328 <listOfReactants>
16329 <speciesReference species="M_fe2_c" stoichiometry="1.000000"/>
16330 <speciesReference species="M_scl_c" stoichiometry="1.000000"/>
16331 </listOfReactants>
16332 <listOfProducts>
16333 <speciesReference species="M_h_c" stoichiometry="3.000000"/>
16334 <speciesReference species="M_sheme_c" stoichiometry="1.000000"/>
16335 </listOfProducts>
16336 </reaction>
16337 <reaction id="R_SHK3Dr" name="R_shikimate_dehydrogenase" reversible="true">
16338 <notes>
16339 <html:p>GENE_ASSOCIATION: ( b3281 or b1692 )</html:p>
16340 <html:p>PROTEIN_ASSOCIATION: ( AroEec ) or ( YdiB )</html:p>
16341 <html:p>SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism</html:p>
16342 <html:p>PROTEIN_CLASS: 1.1.1.25</html:p>
16343 </notes>
16344 <listOfReactants>
16345 <speciesReference species="M_3dhsk_c" stoichiometry="1.000000"/>
16346 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
16347 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
16348 </listOfReactants>
16349 <listOfProducts>
16350 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
16351 <speciesReference species="M_skm_c" stoichiometry="1.000000"/>
16352 </listOfProducts>
16353 </reaction>
16354 <reaction id="R_SHKK" name="R_shikimate_kinase" reversible="false">
16355 <notes>
16356 <html:p>GENE_ASSOCIATION: ( b3390 or b0388 )</html:p>
16357 <html:p>PROTEIN_ASSOCIATION: ( AroK ) or ( AroL )</html:p>
16358 <html:p>SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism</html:p>
16359 <html:p>PROTEIN_CLASS: 2.7.1.71</html:p>
16360 </notes>
16361 <listOfReactants>
16362 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
16363 <speciesReference species="M_skm_c" stoichiometry="1.000000"/>
16364 </listOfReactants>
16365 <listOfProducts>
16366 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
16367 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
16368 <speciesReference species="M_skm5p_c" stoichiometry="1.000000"/>
16369 </listOfProducts>
16370 </reaction>
16371 <reaction id="R_SHSL1" name="R_O_succinylhomoserine_lyase__L_cysteine_" reversible="false">
16372 <notes>
16373 <html:p>GENE_ASSOCIATION: b3939</html:p>
16374 <html:p>PROTEIN_ASSOCIATION: MetB</html:p>
16375 <html:p>SUBSYSTEM: S_Methionine_Metabolism</html:p>
16376 <html:p>PROTEIN_CLASS: 4.2.99.9</html:p>
16377 </notes>
16378 <listOfReactants>
16379 <speciesReference species="M_cys_L_c" stoichiometry="1.000000"/>
16380 <speciesReference species="M_suchms_c" stoichiometry="1.000000"/>
16381 </listOfReactants>
16382 <listOfProducts>
16383 <speciesReference species="M_cyst_L_c" stoichiometry="1.000000"/>
16384 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
16385 <speciesReference species="M_succ_c" stoichiometry="1.000000"/>
16386 </listOfProducts>
16387 </reaction>
16388 <reaction id="R_SOTA" name="R_Succinylornithine_transaminase" reversible="false">
16389 <notes>
16390 <html:p>GENE_ASSOCIATION: b1745</html:p>
16391 <html:p>PROTEIN_ASSOCIATION: AstB</html:p>
16392 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
16393 <html:p>PROTEIN_CLASS: </html:p>
16394 </notes>
16395 <listOfReactants>
16396 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
16397 <speciesReference species="M_sucorn_c" stoichiometry="1.000000"/>
16398 </listOfReactants>
16399 <listOfProducts>
16400 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
16401 <speciesReference species="M_sucgsa_c" stoichiometry="1.000000"/>
16402 </listOfProducts>
16403 </reaction>
16404 <reaction id="R_SPMDAT1" name="R_Spermidine_acetyltransferase" reversible="false">
16405 <notes>
16406 <html:p>GENE_ASSOCIATION: b1584</html:p>
16407 <html:p>PROTEIN_ASSOCIATION: SpeG</html:p>
16408 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
16409 <html:p>PROTEIN_CLASS: 2.3.1.57</html:p>
16410 </notes>
16411 <listOfReactants>
16412 <speciesReference species="M_accoa_c" stoichiometry="1.000000"/>
16413 <speciesReference species="M_spmd_c" stoichiometry="1.000000"/>
16414 </listOfReactants>
16415 <listOfProducts>
16416 <speciesReference species="M_N1aspmd_c" stoichiometry="1.000000"/>
16417 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
16418 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
16419 </listOfProducts>
16420 </reaction>
16421 <reaction id="R_SPMDAT2" name="R_Spermidine_acetyltransferase__N8_" reversible="false">
16422 <notes>
16423 <html:p>GENE_ASSOCIATION: b1584</html:p>
16424 <html:p>PROTEIN_ASSOCIATION: SpeG</html:p>
16425 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
16426 <html:p>PROTEIN_CLASS: 2.3.1.57</html:p>
16427 </notes>
16428 <listOfReactants>
16429 <speciesReference species="M_accoa_c" stoichiometry="1.000000"/>
16430 <speciesReference species="M_spmd_c" stoichiometry="1.000000"/>
16431 </listOfReactants>
16432 <listOfProducts>
16433 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
16434 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
16435 <speciesReference species="M_n8aspmd_c" stoichiometry="1.000000"/>
16436 </listOfProducts>
16437 </reaction>
16438 <reaction id="R_SPMDabc" name="R_spermidine_transport_via_ABC_system" reversible="false">
16439 <notes>
16440 <html:p>GENE_ASSOCIATION: ( ( b1126 and b1125 and b1124 and b1123 ) or ( b1440 and b1441 and b1442 and b1443 ) )</html:p>
16441 <html:p>PROTEIN_ASSOCIATION: ( PotA and PotB and PotC and PotDec ) or ( YdcS and YdcT and YdcU and YdcV )</html:p>
16442 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
16443 <html:p>PROTEIN_CLASS: </html:p>
16444 </notes>
16445 <listOfReactants>
16446 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
16447 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
16448 <speciesReference species="M_spmd_e" stoichiometry="1.000000"/>
16449 </listOfReactants>
16450 <listOfProducts>
16451 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
16452 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
16453 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
16454 <speciesReference species="M_spmd_c" stoichiometry="1.000000"/>
16455 </listOfProducts>
16456 </reaction>
16457 <reaction id="R_SPMS" name="R_spermidine_synthase" reversible="false">
16458 <notes>
16459 <html:p>GENE_ASSOCIATION: b0121</html:p>
16460 <html:p>PROTEIN_ASSOCIATION: SpeE</html:p>
16461 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
16462 <html:p>PROTEIN_CLASS: 2.5.1.16</html:p>
16463 </notes>
16464 <listOfReactants>
16465 <speciesReference species="M_ametam_c" stoichiometry="1.000000"/>
16466 <speciesReference species="M_ptrc_c" stoichiometry="1.000000"/>
16467 </listOfReactants>
16468 <listOfProducts>
16469 <speciesReference species="M_5mta_c" stoichiometry="1.000000"/>
16470 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
16471 <speciesReference species="M_spmd_c" stoichiometry="1.000000"/>
16472 </listOfProducts>
16473 </reaction>
16474 <reaction id="R_SPODM" name="R_superoxide_dismutase" reversible="false">
16475 <notes>
16476 <html:p>GENE_ASSOCIATION: ( b3908 or b1656 or b1646 )</html:p>
16477 <html:p>PROTEIN_ASSOCIATION: ( SodA ) or ( SodB ) or ( SodC )</html:p>
16478 <html:p>SUBSYSTEM: S_Unassigned</html:p>
16479 <html:p>PROTEIN_CLASS: 1.15.1.1</html:p>
16480 </notes>
16481 <listOfReactants>
16482 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
16483 <speciesReference species="M_o2s_c" stoichiometry="2.000000"/>
16484 </listOfReactants>
16485 <listOfProducts>
16486 <speciesReference species="M_h2o2_c" stoichiometry="1.000000"/>
16487 <speciesReference species="M_o2_c" stoichiometry="1.000000"/>
16488 </listOfProducts>
16489 </reaction>
16490 <reaction id="R_SSALx" name="R_succinate_semialdehyde_dehydrogenase__NAD_" reversible="false">
16491 <notes>
16492 <html:p>GENE_ASSOCIATION: </html:p>
16493 <html:p>PROTEIN_ASSOCIATION: </html:p>
16494 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
16495 <html:p>PROTEIN_CLASS: 1.2.1.16</html:p>
16496 </notes>
16497 <listOfReactants>
16498 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
16499 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
16500 <speciesReference species="M_sucsal_c" stoichiometry="1.000000"/>
16501 </listOfReactants>
16502 <listOfProducts>
16503 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
16504 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
16505 <speciesReference species="M_succ_c" stoichiometry="1.000000"/>
16506 </listOfProducts>
16507 </reaction>
16508 <reaction id="R_SSALy" name="R_succinate_semialdehyde_dehydrogenase__NADP_" reversible="false">
16509 <notes>
16510 <html:p>GENE_ASSOCIATION: b2661</html:p>
16511 <html:p>PROTEIN_ASSOCIATION: GabD</html:p>
16512 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
16513 <html:p>PROTEIN_CLASS: 1.2.1.16</html:p>
16514 </notes>
16515 <listOfReactants>
16516 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
16517 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
16518 <speciesReference species="M_sucsal_c" stoichiometry="1.000000"/>
16519 </listOfReactants>
16520 <listOfProducts>
16521 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
16522 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
16523 <speciesReference species="M_succ_c" stoichiometry="1.000000"/>
16524 </listOfProducts>
16525 </reaction>
16526 <reaction id="R_SUCBZL" name="R_o_succinylbenzoate_CoA_ligase" reversible="false">
16527 <notes>
16528 <html:p>GENE_ASSOCIATION: b2260</html:p>
16529 <html:p>PROTEIN_ASSOCIATION: MenE</html:p>
16530 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
16531 <html:p>PROTEIN_CLASS: 6.2.1.26</html:p>
16532 </notes>
16533 <listOfReactants>
16534 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
16535 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
16536 <speciesReference species="M_sucbz_c" stoichiometry="1.000000"/>
16537 </listOfReactants>
16538 <listOfProducts>
16539 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
16540 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
16541 <speciesReference species="M_sbzcoa_c" stoichiometry="1.000000"/>
16542 </listOfProducts>
16543 </reaction>
16544 <reaction id="R_SUCBZS" name="R_O_succinylbenzoate_CoA_synthase" reversible="false">
16545 <notes>
16546 <html:p>GENE_ASSOCIATION: b2261</html:p>
16547 <html:p>PROTEIN_ASSOCIATION: MenC</html:p>
16548 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
16549 <html:p>PROTEIN_CLASS: </html:p>
16550 </notes>
16551 <listOfReactants>
16552 <speciesReference species="M_2shchc_c" stoichiometry="1.000000"/>
16553 </listOfReactants>
16554 <listOfProducts>
16555 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
16556 <speciesReference species="M_sucbz_c" stoichiometry="1.000000"/>
16557 </listOfProducts>
16558 </reaction>
16559 <reaction id="R_SUCCabc" name="R_Succinate_transport_via_ABC_system" reversible="false">
16560 <notes>
16561 <html:p>GENE_ASSOCIATION: b3579</html:p>
16562 <html:p>PROTEIN_ASSOCIATION: YiaO</html:p>
16563 <html:p>SUBSYSTEM: S_Putative_Transporters</html:p>
16564 <html:p>PROTEIN_CLASS: </html:p>
16565 </notes>
16566 <listOfReactants>
16567 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
16568 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
16569 <speciesReference species="M_succ_e" stoichiometry="1.000000"/>
16570 </listOfReactants>
16571 <listOfProducts>
16572 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
16573 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
16574 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
16575 <speciesReference species="M_succ_c" stoichiometry="1.000000"/>
16576 </listOfProducts>
16577 </reaction>
16578 <reaction id="R_SUCCt2_2" name="R_succinate_transport_via_proton_symport__2_H_" reversible="false">
16579 <notes>
16580 <html:p>GENE_ASSOCIATION: b3528</html:p>
16581 <html:p>PROTEIN_ASSOCIATION: DctA</html:p>
16582 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
16583 <html:p>PROTEIN_CLASS: </html:p>
16584 </notes>
16585 <listOfReactants>
16586 <speciesReference species="M_h_e" stoichiometry="2.000000"/>
16587 <speciesReference species="M_succ_e" stoichiometry="1.000000"/>
16588 </listOfReactants>
16589 <listOfProducts>
16590 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
16591 <speciesReference species="M_succ_c" stoichiometry="1.000000"/>
16592 </listOfProducts>
16593 </reaction>
16594 <reaction id="R_SUCCt2_3" name="R_Succintate_transport_via_proton_symport__3_H_" reversible="false">
16595 <notes>
16596 <html:p>GENE_ASSOCIATION: ( b4138 or b4123 )</html:p>
16597 <html:p>PROTEIN_ASSOCIATION: ( DcuA ) or ( DcuB )</html:p>
16598 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
16599 <html:p>PROTEIN_CLASS: </html:p>
16600 </notes>
16601 <listOfReactants>
16602 <speciesReference species="M_h_e" stoichiometry="3.000000"/>
16603 <speciesReference species="M_succ_e" stoichiometry="1.000000"/>
16604 </listOfReactants>
16605 <listOfProducts>
16606 <speciesReference species="M_h_c" stoichiometry="3.000000"/>
16607 <speciesReference species="M_succ_c" stoichiometry="1.000000"/>
16608 </listOfProducts>
16609 </reaction>
16610 <reaction id="R_SUCCt2b" name="R_Succinate_efflux_via_proton_symport" reversible="false">
16611 <notes>
16612 <html:p>GENE_ASSOCIATION: b0621</html:p>
16613 <html:p>PROTEIN_ASSOCIATION: DcuC</html:p>
16614 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
16615 <html:p>PROTEIN_CLASS: </html:p>
16616 </notes>
16617 <listOfReactants>
16618 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
16619 <speciesReference species="M_succ_c" stoichiometry="1.000000"/>
16620 </listOfReactants>
16621 <listOfProducts>
16622 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
16623 <speciesReference species="M_succ_e" stoichiometry="1.000000"/>
16624 </listOfProducts>
16625 </reaction>
16626 <reaction id="R_SUCD1i" name="R_succinate_dehydrogenase" reversible="false">
16627 <notes>
16628 <html:p>GENE_ASSOCIATION: ( b0721 and b0722 and b0723 and b0724 )</html:p>
16629 <html:p>PROTEIN_ASSOCIATION: Sdh</html:p>
16630 <html:p>SUBSYSTEM: S_Citric_Acid_Cycle</html:p>
16631 <html:p>PROTEIN_CLASS: 1.3.99.1</html:p>
16632 </notes>
16633 <listOfReactants>
16634 <speciesReference species="M_fad_c" stoichiometry="1.000000"/>
16635 <speciesReference species="M_succ_c" stoichiometry="1.000000"/>
16636 </listOfReactants>
16637 <listOfProducts>
16638 <speciesReference species="M_fadh2_c" stoichiometry="1.000000"/>
16639 <speciesReference species="M_fum_c" stoichiometry="1.000000"/>
16640 </listOfProducts>
16641 </reaction>
16642 <reaction id="R_SUCD4" name="R_succinate_dehyrdogenase" reversible="true">
16643 <notes>
16644 <html:p>GENE_ASSOCIATION: ( b0721 and b0722 and b0723 and b0724 )</html:p>
16645 <html:p>PROTEIN_ASSOCIATION: Sdh</html:p>
16646 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
16647 <html:p>PROTEIN_CLASS: </html:p>
16648 </notes>
16649 <listOfReactants>
16650 <speciesReference species="M_fadh2_c" stoichiometry="1.000000"/>
16651 <speciesReference species="M_q8_c" stoichiometry="1.000000"/>
16652 </listOfReactants>
16653 <listOfProducts>
16654 <speciesReference species="M_fad_c" stoichiometry="1.000000"/>
16655 <speciesReference species="M_q8h2_c" stoichiometry="1.000000"/>
16656 </listOfProducts>
16657 </reaction>
16658 <reaction id="R_SUCFUMt" name="R_succinatefumarate_antiporter" reversible="true">
16659 <notes>
16660 <html:p>GENE_ASSOCIATION: ( b4138 or b4123 or b0621 )</html:p>
16661 <html:p>PROTEIN_ASSOCIATION: ( DcuA ) or ( DcuB ) or ( DcuC )</html:p>
16662 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
16663 <html:p>PROTEIN_CLASS: </html:p>
16664 </notes>
16665 <listOfReactants>
16666 <speciesReference species="M_succ_c" stoichiometry="1.000000"/>
16667 <speciesReference species="M_fum_e" stoichiometry="1.000000"/>
16668 </listOfReactants>
16669 <listOfProducts>
16670 <speciesReference species="M_fum_c" stoichiometry="1.000000"/>
16671 <speciesReference species="M_succ_e" stoichiometry="1.000000"/>
16672 </listOfProducts>
16673 </reaction>
16674 <reaction id="R_SUCOAS" name="R_succinyl_CoA_synthetase__ADP_forming_" reversible="true">
16675 <notes>
16676 <html:p>GENE_ASSOCIATION: ( b0728 and b0729 )</html:p>
16677 <html:p>PROTEIN_ASSOCIATION: SucC</html:p>
16678 <html:p>SUBSYSTEM: S_Citric_Acid_Cycle</html:p>
16679 <html:p>PROTEIN_CLASS: 6.2.1.5</html:p>
16680 </notes>
16681 <listOfReactants>
16682 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
16683 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
16684 <speciesReference species="M_succ_c" stoichiometry="1.000000"/>
16685 </listOfReactants>
16686 <listOfProducts>
16687 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
16688 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
16689 <speciesReference species="M_succoa_c" stoichiometry="1.000000"/>
16690 </listOfProducts>
16691 </reaction>
16692 <reaction id="R_SUCpts" name="R_sucrose_transport_via_PEPPyr_PTS" reversible="false">
16693 <notes>
16694 <html:p>GENE_ASSOCIATION: ( b2417 and b2415 and b2416 and b2429 )</html:p>
16695 <html:p>PROTEIN_ASSOCIATION: ( Crr and PtsH and PtsI and ScrA )</html:p>
16696 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
16697 <html:p>PROTEIN_CLASS: </html:p>
16698 </notes>
16699 <listOfReactants>
16700 <speciesReference species="M_pep_c" stoichiometry="1.000000"/>
16701 <speciesReference species="M_sucr_e" stoichiometry="1.000000"/>
16702 </listOfReactants>
16703 <listOfProducts>
16704 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
16705 <speciesReference species="M_suc6p_c" stoichiometry="1.000000"/>
16706 </listOfProducts>
16707 </reaction>
16708 <reaction id="R_SULR" name="R_sulfite_reductase__NADPH2_" reversible="true">
16709 <notes>
16710 <html:p>GENE_ASSOCIATION: ( b2763 and b2764 )</html:p>
16711 <html:p>PROTEIN_ASSOCIATION: CysIJ</html:p>
16712 <html:p>SUBSYSTEM: S_Cysteine_Metabolism</html:p>
16713 <html:p>PROTEIN_CLASS: 1.8.2.2</html:p>
16714 </notes>
16715 <listOfReactants>
16716 <speciesReference species="M_h2o_c" stoichiometry="3.000000"/>
16717 <speciesReference species="M_h2s_c" stoichiometry="1.000000"/>
16718 <speciesReference species="M_nadp_c" stoichiometry="3.000000"/>
16719 </listOfReactants>
16720 <listOfProducts>
16721 <speciesReference species="M_h_c" stoichiometry="5.000000"/>
16722 <speciesReference species="M_nadph_c" stoichiometry="3.000000"/>
16723 <speciesReference species="M_so3_c" stoichiometry="1.000000"/>
16724 </listOfProducts>
16725 </reaction>
16726 <reaction id="R_SULabc" name="R_sulfate_transport_via_ABC_system" reversible="false">
16727 <notes>
16728 <html:p>GENE_ASSOCIATION: ( ( b2422 and b2424 and b2423 and b2413 and b3917 ) or ( b2422 and b2425 and b2424 and b2423 ) )</html:p>
16729 <html:p>PROTEIN_ASSOCIATION: ( CysA and CysU and CysW and CysZ and Sbp ) or ( CysA and CysP and CysU and CysW )</html:p>
16730 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
16731 <html:p>PROTEIN_CLASS: </html:p>
16732 </notes>
16733 <listOfReactants>
16734 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
16735 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
16736 <speciesReference species="M_so4_e" stoichiometry="1.000000"/>
16737 </listOfReactants>
16738 <listOfProducts>
16739 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
16740 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
16741 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
16742 <speciesReference species="M_so4_c" stoichiometry="1.000000"/>
16743 </listOfProducts>
16744 </reaction>
16745 <reaction id="R_TAGURr" name="R_tagaturonate_reductase" reversible="true">
16746 <notes>
16747 <html:p>GENE_ASSOCIATION: b1521</html:p>
16748 <html:p>PROTEIN_ASSOCIATION: UxaB</html:p>
16749 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
16750 <html:p>PROTEIN_CLASS: 1.1.1.58</html:p>
16751 </notes>
16752 <listOfReactants>
16753 <speciesReference species="M_altrn_c" stoichiometry="1.000000"/>
16754 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
16755 </listOfReactants>
16756 <listOfProducts>
16757 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
16758 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
16759 <speciesReference species="M_tagur_c" stoichiometry="1.000000"/>
16760 </listOfProducts>
16761 </reaction>
16762 <reaction id="R_TALA" name="R_transaldolase" reversible="true">
16763 <notes>
16764 <html:p>GENE_ASSOCIATION: ( b0008 or b2464 )</html:p>
16765 <html:p>PROTEIN_ASSOCIATION: ( TalB ) or ( TalA )</html:p>
16766 <html:p>SUBSYSTEM: S_Pentose_Phosphate_Pathway</html:p>
16767 <html:p>PROTEIN_CLASS: 2.2.1.2</html:p>
16768 </notes>
16769 <listOfReactants>
16770 <speciesReference species="M_g3p_c" stoichiometry="1.000000"/>
16771 <speciesReference species="M_s7p_c" stoichiometry="1.000000"/>
16772 </listOfReactants>
16773 <listOfProducts>
16774 <speciesReference species="M_e4p_c" stoichiometry="1.000000"/>
16775 <speciesReference species="M_f6p_c" stoichiometry="1.000000"/>
16776 </listOfProducts>
16777 </reaction>
16778 <reaction id="R_TARTD" name="R_L___tartrate_dehydratase" reversible="false">
16779 <notes>
16780 <html:p>GENE_ASSOCIATION: ( b3061 and b3062 )</html:p>
16781 <html:p>PROTEIN_ASSOCIATION: TtdAB</html:p>
16782 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
16783 <html:p>PROTEIN_CLASS: 4.2.1.32</html:p>
16784 </notes>
16785 <listOfReactants>
16786 <speciesReference species="M_tartr_L_c" stoichiometry="1.000000"/>
16787 </listOfReactants>
16788 <listOfProducts>
16789 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
16790 <speciesReference species="M_oaa_c" stoichiometry="1.000000"/>
16791 </listOfProducts>
16792 </reaction>
16793 <reaction id="R_TARTRt7" name="R_Tartratesuccinate_antiporter" reversible="true">
16794 <notes>
16795 <html:p>GENE_ASSOCIATION: b3063</html:p>
16796 <html:p>PROTEIN_ASSOCIATION: YgjE</html:p>
16797 <html:p>SUBSYSTEM: S_Putative_Transporters</html:p>
16798 <html:p>PROTEIN_CLASS: </html:p>
16799 </notes>
16800 <listOfReactants>
16801 <speciesReference species="M_succ_c" stoichiometry="1.000000"/>
16802 <speciesReference species="M_tartr_L_e" stoichiometry="1.000000"/>
16803 </listOfReactants>
16804 <listOfProducts>
16805 <speciesReference species="M_tartr_L_c" stoichiometry="1.000000"/>
16806 <speciesReference species="M_succ_e" stoichiometry="1.000000"/>
16807 </listOfProducts>
16808 </reaction>
16809 <reaction id="R_TAUDO" name="R_Taurine_dioxygenase" reversible="false">
16810 <notes>
16811 <html:p>GENE_ASSOCIATION: b0368</html:p>
16812 <html:p>PROTEIN_ASSOCIATION: TauD</html:p>
16813 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
16814 <html:p>PROTEIN_CLASS: 1.14.11.17</html:p>
16815 </notes>
16816 <listOfReactants>
16817 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
16818 <speciesReference species="M_o2_c" stoichiometry="1.000000"/>
16819 <speciesReference species="M_taur_c" stoichiometry="1.000000"/>
16820 </listOfReactants>
16821 <listOfProducts>
16822 <speciesReference species="M_aacald_c" stoichiometry="1.000000"/>
16823 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
16824 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
16825 <speciesReference species="M_so3_c" stoichiometry="1.000000"/>
16826 <speciesReference species="M_succ_c" stoichiometry="1.000000"/>
16827 </listOfProducts>
16828 </reaction>
16829 <reaction id="R_TAURabc" name="R_taurine_transport_via_ABC_system" reversible="false">
16830 <notes>
16831 <html:p>GENE_ASSOCIATION: ( b0365 and b0366 and b0367 )</html:p>
16832 <html:p>PROTEIN_ASSOCIATION: ( TauA and TauB and TauC )</html:p>
16833 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
16834 <html:p>PROTEIN_CLASS: </html:p>
16835 </notes>
16836 <listOfReactants>
16837 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
16838 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
16839 <speciesReference species="M_taur_e" stoichiometry="1.000000"/>
16840 </listOfReactants>
16841 <listOfProducts>
16842 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
16843 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
16844 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
16845 <speciesReference species="M_taur_c" stoichiometry="1.000000"/>
16846 </listOfProducts>
16847 </reaction>
16848 <reaction id="R_TDPADGAT" name="R_dTDP_4_amino_4_6_dideoxy_D_glucose_acetyltransferase" reversible="false">
16849 <notes>
16850 <html:p>GENE_ASSOCIATION: b3790</html:p>
16851 <html:p>PROTEIN_ASSOCIATION: WecD</html:p>
16852 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
16853 <html:p>PROTEIN_CLASS: </html:p>
16854 </notes>
16855 <listOfReactants>
16856 <speciesReference species="M_accoa_c" stoichiometry="1.000000"/>
16857 <speciesReference species="M_dtdp4addg_c" stoichiometry="1.000000"/>
16858 </listOfReactants>
16859 <listOfProducts>
16860 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
16861 <speciesReference species="M_dtdp4aaddg_c" stoichiometry="1.000000"/>
16862 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
16863 </listOfProducts>
16864 </reaction>
16865 <reaction id="R_TDPAGTA" name="R_dTDP_4_amino_4_6_dideoxy_D_glucose_transaminase" reversible="false">
16866 <notes>
16867 <html:p>GENE_ASSOCIATION: b3791</html:p>
16868 <html:p>PROTEIN_ASSOCIATION: WecE</html:p>
16869 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
16870 <html:p>PROTEIN_CLASS: 2.6.1.33</html:p>
16871 </notes>
16872 <listOfReactants>
16873 <speciesReference species="M_dtdp4d6dg_c" stoichiometry="1.000000"/>
16874 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
16875 </listOfReactants>
16876 <listOfProducts>
16877 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
16878 <speciesReference species="M_dtdp4addg_c" stoichiometry="1.000000"/>
16879 </listOfProducts>
16880 </reaction>
16881 <reaction id="R_TDPDRE" name="R_dTDP_4_dehydrorhamnose_3_5_epimerase" reversible="false">
16882 <notes>
16883 <html:p>GENE_ASSOCIATION: b2038</html:p>
16884 <html:p>PROTEIN_ASSOCIATION: RfbC</html:p>
16885 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
16886 <html:p>PROTEIN_CLASS: 5.1.3.13</html:p>
16887 </notes>
16888 <listOfReactants>
16889 <speciesReference species="M_dtdp4d6dg_c" stoichiometry="1.000000"/>
16890 </listOfReactants>
16891 <listOfProducts>
16892 <speciesReference species="M_dtdp4d6dm_c" stoichiometry="1.000000"/>
16893 </listOfProducts>
16894 </reaction>
16895 <reaction id="R_TDPDRR" name="R_dTDP_4_dehydrorhamnose_reductase" reversible="false">
16896 <notes>
16897 <html:p>GENE_ASSOCIATION: b2040</html:p>
16898 <html:p>PROTEIN_ASSOCIATION: RfbD</html:p>
16899 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
16900 <html:p>PROTEIN_CLASS: 1.1.1.133</html:p>
16901 </notes>
16902 <listOfReactants>
16903 <speciesReference species="M_dtdp4d6dm_c" stoichiometry="1.000000"/>
16904 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
16905 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
16906 </listOfReactants>
16907 <listOfProducts>
16908 <speciesReference species="M_dtdprmn_c" stoichiometry="1.000000"/>
16909 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
16910 </listOfProducts>
16911 </reaction>
16912 <reaction id="R_TDPGDH" name="R_dTDPglucose_4_6_dehydratase" reversible="false">
16913 <notes>
16914 <html:p>GENE_ASSOCIATION: ( b2041 or b3788 )</html:p>
16915 <html:p>PROTEIN_ASSOCIATION: ( RfbB ) or ( RffG )</html:p>
16916 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
16917 <html:p>PROTEIN_CLASS: 4.2.1.46</html:p>
16918 </notes>
16919 <listOfReactants>
16920 <speciesReference species="M_dtdpglu_c" stoichiometry="1.000000"/>
16921 </listOfReactants>
16922 <listOfProducts>
16923 <speciesReference species="M_dtdp4d6dg_c" stoichiometry="1.000000"/>
16924 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
16925 </listOfProducts>
16926 </reaction>
16927 <reaction id="R_TDSK" name="R_Tetraacyldisaccharide_4_kinase" reversible="false">
16928 <notes>
16929 <html:p>GENE_ASSOCIATION: b0915</html:p>
16930 <html:p>PROTEIN_ASSOCIATION: LpxK</html:p>
16931 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
16932 <html:p>PROTEIN_CLASS: 2.7.1.130</html:p>
16933 </notes>
16934 <listOfReactants>
16935 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
16936 <speciesReference species="M_lipidAds_c" stoichiometry="1.000000"/>
16937 </listOfReactants>
16938 <listOfProducts>
16939 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
16940 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
16941 <speciesReference species="M_lipidA_c" stoichiometry="1.000000"/>
16942 </listOfProducts>
16943 </reaction>
16944 <reaction id="R_TGBPA" name="R_Tagatose_bisphosphate_aldolase" reversible="true">
16945 <notes>
16946 <html:p>GENE_ASSOCIATION: ( ( b3132 and b3137 ) or ( b2095 and b2096 ) )</html:p>
16947 <html:p>PROTEIN_ASSOCIATION: ( AgaZ ) or ( GatZ )</html:p>
16948 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
16949 <html:p>PROTEIN_CLASS: 4.1.2.40</html:p>
16950 </notes>
16951 <listOfReactants>
16952 <speciesReference species="M_tagdp_D_c" stoichiometry="1.000000"/>
16953 </listOfReactants>
16954 <listOfProducts>
16955 <speciesReference species="M_dhap_c" stoichiometry="1.000000"/>
16956 <speciesReference species="M_g3p_c" stoichiometry="1.000000"/>
16957 </listOfProducts>
16958 </reaction>
16959 <reaction id="R_THD2" name="R_NAD_P__transhydrogenase" reversible="false">
16960 <notes>
16961 <html:p>GENE_ASSOCIATION: ( b1602 and b1603 )</html:p>
16962 <html:p>PROTEIN_ASSOCIATION: Pnt</html:p>
16963 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
16964 <html:p>PROTEIN_CLASS: 1.6.1.1</html:p>
16965 </notes>
16966 <listOfReactants>
16967 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
16968 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
16969 <speciesReference species="M_h_e" stoichiometry="2.000000"/>
16970 </listOfReactants>
16971 <listOfProducts>
16972 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
16973 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
16974 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
16975 </listOfProducts>
16976 </reaction>
16977 <reaction id="R_THDPS" name="R_tetrahydrodipicolinate_succinylase" reversible="false">
16978 <notes>
16979 <html:p>GENE_ASSOCIATION: b0166</html:p>
16980 <html:p>PROTEIN_ASSOCIATION: DapD</html:p>
16981 <html:p>SUBSYSTEM: S_Threonine_and_Lysine_Metabolism</html:p>
16982 <html:p>PROTEIN_CLASS: 2.3.1.117</html:p>
16983 </notes>
16984 <listOfReactants>
16985 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
16986 <speciesReference species="M_succoa_c" stoichiometry="1.000000"/>
16987 <speciesReference species="M_thdp_c" stoichiometry="1.000000"/>
16988 </listOfReactants>
16989 <listOfProducts>
16990 <speciesReference species="M_coa_c" stoichiometry="1.000000"/>
16991 <speciesReference species="M_sl2a6o_c" stoichiometry="1.000000"/>
16992 </listOfProducts>
16993 </reaction>
16994 <reaction id="R_THMDt2" name="R_thymidine_transport_in_via_proton_symport" reversible="false">
16995 <notes>
16996 <html:p>GENE_ASSOCIATION: ( b2964 or b2393 )</html:p>
16997 <html:p>PROTEIN_ASSOCIATION: ( NupG ) or ( NupCec )</html:p>
16998 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
16999 <html:p>PROTEIN_CLASS: </html:p>
17000 </notes>
17001 <listOfReactants>
17002 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
17003 <speciesReference species="M_thymd_e" stoichiometry="1.000000"/>
17004 </listOfReactants>
17005 <listOfProducts>
17006 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17007 <speciesReference species="M_thymd_c" stoichiometry="1.000000"/>
17008 </listOfProducts>
17009 </reaction>
17010 <reaction id="R_THMDt2r" name="R_thymidine_transport_in_via_proton_symport__reversible" reversible="true">
17011 <notes>
17012 <html:p>GENE_ASSOCIATION: b2406</html:p>
17013 <html:p>PROTEIN_ASSOCIATION: XapB</html:p>
17014 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
17015 <html:p>PROTEIN_CLASS: </html:p>
17016 </notes>
17017 <listOfReactants>
17018 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
17019 <speciesReference species="M_thymd_e" stoichiometry="1.000000"/>
17020 </listOfReactants>
17021 <listOfProducts>
17022 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17023 <speciesReference species="M_thymd_c" stoichiometry="1.000000"/>
17024 </listOfProducts>
17025 </reaction>
17026 <reaction id="R_THMabc" name="R_thiamine_transport_via_ABC_system" reversible="false">
17027 <notes>
17028 <html:p>GENE_ASSOCIATION: ( b0068 and b0067 and b0066 )</html:p>
17029 <html:p>PROTEIN_ASSOCIATION: ( SfuA and SfuB and SfuC )</html:p>
17030 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
17031 <html:p>PROTEIN_CLASS: </html:p>
17032 </notes>
17033 <listOfReactants>
17034 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
17035 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
17036 <speciesReference species="M_thm_e" stoichiometry="1.000000"/>
17037 </listOfReactants>
17038 <listOfProducts>
17039 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
17040 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17041 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
17042 <speciesReference species="M_thm_c" stoichiometry="1.000000"/>
17043 </listOfProducts>
17044 </reaction>
17045 <reaction id="R_THRAr" name="R_Threonine_Aldolase" reversible="true">
17046 <notes>
17047 <html:p>GENE_ASSOCIATION: ( b0870 or b2551 )</html:p>
17048 <html:p>PROTEIN_ASSOCIATION: ( LtaA ) or ( GlyA )</html:p>
17049 <html:p>SUBSYSTEM: S_Threonine_and_Lysine_Metabolism</html:p>
17050 <html:p>PROTEIN_CLASS: 4.1.2.5</html:p>
17051 </notes>
17052 <listOfReactants>
17053 <speciesReference species="M_thr_L_c" stoichiometry="1.000000"/>
17054 </listOfReactants>
17055 <listOfProducts>
17056 <speciesReference species="M_acald_c" stoichiometry="1.000000"/>
17057 <speciesReference species="M_gly_c" stoichiometry="1.000000"/>
17058 </listOfProducts>
17059 </reaction>
17060 <reaction id="R_THRD" name="R_L_threonine_dehydrogenase" reversible="false">
17061 <notes>
17062 <html:p>GENE_ASSOCIATION: b3616</html:p>
17063 <html:p>PROTEIN_ASSOCIATION: Tdh</html:p>
17064 <html:p>SUBSYSTEM: S_Glycine_and_Serine_Metabolism</html:p>
17065 <html:p>PROTEIN_CLASS: 1.1.1.103</html:p>
17066 </notes>
17067 <listOfReactants>
17068 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
17069 <speciesReference species="M_thr_L_c" stoichiometry="1.000000"/>
17070 </listOfReactants>
17071 <listOfProducts>
17072 <speciesReference species="M_2aobut_c" stoichiometry="1.000000"/>
17073 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17074 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
17075 </listOfProducts>
17076 </reaction>
17077 <reaction id="R_THRD_L" name="R_L_threonine_deaminase" reversible="false">
17078 <notes>
17079 <html:p>GENE_ASSOCIATION: ( b3117 or b1814 or b2797 or b3772 )</html:p>
17080 <html:p>PROTEIN_ASSOCIATION: ( TdcB ) or ( SdaAec ) or ( SdaB ) or ( IlvA )</html:p>
17081 <html:p>SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism</html:p>
17082 <html:p>PROTEIN_CLASS: </html:p>
17083 </notes>
17084 <listOfReactants>
17085 <speciesReference species="M_thr_L_c" stoichiometry="1.000000"/>
17086 </listOfReactants>
17087 <listOfProducts>
17088 <speciesReference species="M_2obut_c" stoichiometry="1.000000"/>
17089 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
17090 </listOfProducts>
17091 </reaction>
17092 <reaction id="R_THRS" name="R_threonine_synthase" reversible="false">
17093 <notes>
17094 <html:p>GENE_ASSOCIATION: b0004</html:p>
17095 <html:p>PROTEIN_ASSOCIATION: ThrC</html:p>
17096 <html:p>SUBSYSTEM: S_Threonine_and_Lysine_Metabolism</html:p>
17097 <html:p>PROTEIN_CLASS: 4.2.3.1</html:p>
17098 </notes>
17099 <listOfReactants>
17100 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
17101 <speciesReference species="M_phom_c" stoichiometry="1.000000"/>
17102 </listOfReactants>
17103 <listOfProducts>
17104 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
17105 <speciesReference species="M_thr_L_c" stoichiometry="1.000000"/>
17106 </listOfProducts>
17107 </reaction>
17108 <reaction id="R_THRabc" name="R_L_threonine_transport_via_ABC_system" reversible="false">
17109 <notes>
17110 <html:p>GENE_ASSOCIATION: ( b3454 and b3455 and b3457 and b3460 and b3456 )</html:p>
17111 <html:p>PROTEIN_ASSOCIATION: ( LivF and LivG and LivH and LivJ and LivM )</html:p>
17112 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
17113 <html:p>PROTEIN_CLASS: </html:p>
17114 </notes>
17115 <listOfReactants>
17116 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
17117 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
17118 <speciesReference species="M_thr_L_e" stoichiometry="1.000000"/>
17119 </listOfReactants>
17120 <listOfProducts>
17121 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
17122 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17123 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
17124 <speciesReference species="M_thr_L_c" stoichiometry="1.000000"/>
17125 </listOfProducts>
17126 </reaction>
17127 <reaction id="R_THRt2r" name="R_L_threonine_reversible_transport_via_proton_symport" reversible="true">
17128 <notes>
17129 <html:p>GENE_ASSOCIATION: b3116</html:p>
17130 <html:p>PROTEIN_ASSOCIATION: TdcC</html:p>
17131 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
17132 <html:p>PROTEIN_CLASS: </html:p>
17133 </notes>
17134 <listOfReactants>
17135 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
17136 <speciesReference species="M_thr_L_e" stoichiometry="1.000000"/>
17137 </listOfReactants>
17138 <listOfProducts>
17139 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17140 <speciesReference species="M_thr_L_c" stoichiometry="1.000000"/>
17141 </listOfProducts>
17142 </reaction>
17143 <reaction id="R_THRt4" name="R_L_threonine__via_sodium_symport" reversible="false">
17144 <notes>
17145 <html:p>GENE_ASSOCIATION: b3089</html:p>
17146 <html:p>PROTEIN_ASSOCIATION: SstT</html:p>
17147 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
17148 <html:p>PROTEIN_CLASS: </html:p>
17149 </notes>
17150 <listOfReactants>
17151 <speciesReference species="M_na1_e" stoichiometry="1.000000"/>
17152 <speciesReference species="M_thr_L_e" stoichiometry="1.000000"/>
17153 </listOfReactants>
17154 <listOfProducts>
17155 <speciesReference species="M_na1_c" stoichiometry="1.000000"/>
17156 <speciesReference species="M_thr_L_c" stoichiometry="1.000000"/>
17157 </listOfProducts>
17158 </reaction>
17159 <reaction id="R_THZPSN" name="R_thiazole_phosphate_synthesis" reversible="false">
17160 <notes>
17161 <html:p>GENE_ASSOCIATION: ( b2530 and b3992 and ( b3990 and b3991 ) and b0423 and b4407 )</html:p>
17162 <html:p>PROTEIN_ASSOCIATION: ( IscS and ThiFec and ThiGH and ThiI and ThiS )</html:p>
17163 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
17164 <html:p>PROTEIN_CLASS: </html:p>
17165 </notes>
17166 <listOfReactants>
17167 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
17168 <speciesReference species="M_cys_L_c" stoichiometry="1.000000"/>
17169 <speciesReference species="M_dxyl5p_c" stoichiometry="1.000000"/>
17170 <speciesReference species="M_tyr_L_c" stoichiometry="1.000000"/>
17171 </listOfReactants>
17172 <listOfProducts>
17173 <speciesReference species="M_4hba_c" stoichiometry="1.000000"/>
17174 <speciesReference species="M_4mpetz_c" stoichiometry="1.000000"/>
17175 <speciesReference species="M_ala_L_c" stoichiometry="1.000000"/>
17176 <speciesReference species="M_amp_c" stoichiometry="1.000000"/>
17177 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
17178 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17179 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
17180 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
17181 </listOfProducts>
17182 </reaction>
17183 <reaction id="R_TKT1" name="R_transketolase" reversible="true">
17184 <notes>
17185 <html:p>GENE_ASSOCIATION: ( b2935 or b2465 )</html:p>
17186 <html:p>PROTEIN_ASSOCIATION: ( TktA ) or ( TktB )</html:p>
17187 <html:p>SUBSYSTEM: S_Pentose_Phosphate_Pathway</html:p>
17188 <html:p>PROTEIN_CLASS: 2.2.1.1</html:p>
17189 </notes>
17190 <listOfReactants>
17191 <speciesReference species="M_r5p_c" stoichiometry="1.000000"/>
17192 <speciesReference species="M_xu5p_D_c" stoichiometry="1.000000"/>
17193 </listOfReactants>
17194 <listOfProducts>
17195 <speciesReference species="M_g3p_c" stoichiometry="1.000000"/>
17196 <speciesReference species="M_s7p_c" stoichiometry="1.000000"/>
17197 </listOfProducts>
17198 </reaction>
17199 <reaction id="R_TKT2" name="R_transketolase" reversible="true">
17200 <notes>
17201 <html:p>GENE_ASSOCIATION: ( b2935 or b2465 )</html:p>
17202 <html:p>PROTEIN_ASSOCIATION: ( TktA ) or ( TktB )</html:p>
17203 <html:p>SUBSYSTEM: S_Pentose_Phosphate_Pathway</html:p>
17204 <html:p>PROTEIN_CLASS: 2.2.1.1</html:p>
17205 </notes>
17206 <listOfReactants>
17207 <speciesReference species="M_e4p_c" stoichiometry="1.000000"/>
17208 <speciesReference species="M_xu5p_D_c" stoichiometry="1.000000"/>
17209 </listOfReactants>
17210 <listOfProducts>
17211 <speciesReference species="M_f6p_c" stoichiometry="1.000000"/>
17212 <speciesReference species="M_g3p_c" stoichiometry="1.000000"/>
17213 </listOfProducts>
17214 </reaction>
17215 <reaction id="R_TMAOR1" name="R_Trimethylamine_N_oxide_reductase__menaquinol_8_" reversible="false">
17216 <notes>
17217 <html:p>GENE_ASSOCIATION: ( b0894 and b0895 and b0896 )</html:p>
17218 <html:p>PROTEIN_ASSOCIATION: DmsABC</html:p>
17219 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
17220 <html:p>PROTEIN_CLASS: </html:p>
17221 </notes>
17222 <listOfReactants>
17223 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17224 <speciesReference species="M_mql8_c" stoichiometry="1.000000"/>
17225 <speciesReference species="M_tmao_c" stoichiometry="1.000000"/>
17226 </listOfReactants>
17227 <listOfProducts>
17228 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
17229 <speciesReference species="M_mqn8_c" stoichiometry="1.000000"/>
17230 <speciesReference species="M_tma_c" stoichiometry="1.000000"/>
17231 </listOfProducts>
17232 </reaction>
17233 <reaction id="R_TMAOR1e" name="R_Trimethylamine_N_oxide_reductase__menaquinol_8_" reversible="false">
17234 <notes>
17235 <html:p>GENE_ASSOCIATION: ( ( b0997 and b0996 ) or ( b1873 and b1872 ) )</html:p>
17236 <html:p>PROTEIN_ASSOCIATION: ( TorA and TorC ) or ( TorY and TorZ )</html:p>
17237 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
17238 <html:p>PROTEIN_CLASS: </html:p>
17239 </notes>
17240 <listOfReactants>
17241 <speciesReference species="M_mql8_c" stoichiometry="1.000000"/>
17242 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
17243 <speciesReference species="M_tmao_e" stoichiometry="1.000000"/>
17244 </listOfReactants>
17245 <listOfProducts>
17246 <speciesReference species="M_mqn8_c" stoichiometry="1.000000"/>
17247 <speciesReference species="M_h2o_e" stoichiometry="1.000000"/>
17248 <speciesReference species="M_tma_e" stoichiometry="1.000000"/>
17249 </listOfProducts>
17250 </reaction>
17251 <reaction id="R_TMAOR2" name="R_Trimethylamine_N_oxide_reductase__demethylmenaquinol_8_" reversible="false">
17252 <notes>
17253 <html:p>GENE_ASSOCIATION: ( b0894 and b0895 and b0896 )</html:p>
17254 <html:p>PROTEIN_ASSOCIATION: DmsABC</html:p>
17255 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
17256 <html:p>PROTEIN_CLASS: </html:p>
17257 </notes>
17258 <listOfReactants>
17259 <speciesReference species="M_2dmmql8_c" stoichiometry="1.000000"/>
17260 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17261 <speciesReference species="M_tmao_c" stoichiometry="1.000000"/>
17262 </listOfReactants>
17263 <listOfProducts>
17264 <speciesReference species="M_2dmmq8_c" stoichiometry="1.000000"/>
17265 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
17266 <speciesReference species="M_tma_c" stoichiometry="1.000000"/>
17267 </listOfProducts>
17268 </reaction>
17269 <reaction id="R_TMAOR2e" name="R_Trimethylamine_N_oxide_reductase__demethylmenaquinol_8_" reversible="false">
17270 <notes>
17271 <html:p>GENE_ASSOCIATION: ( ( b0997 and b0996 ) or ( b1873 and b1872 ) )</html:p>
17272 <html:p>PROTEIN_ASSOCIATION: ( TorA and TorC ) or ( TorY and TorZ )</html:p>
17273 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
17274 <html:p>PROTEIN_CLASS: </html:p>
17275 </notes>
17276 <listOfReactants>
17277 <speciesReference species="M_2dmmql8_c" stoichiometry="1.000000"/>
17278 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
17279 <speciesReference species="M_tmao_e" stoichiometry="1.000000"/>
17280 </listOfReactants>
17281 <listOfProducts>
17282 <speciesReference species="M_2dmmq8_c" stoichiometry="1.000000"/>
17283 <speciesReference species="M_h2o_e" stoichiometry="1.000000"/>
17284 <speciesReference species="M_tma_e" stoichiometry="1.000000"/>
17285 </listOfProducts>
17286 </reaction>
17287 <reaction id="R_TMDK1" name="R_thymidine_kinase__ATPthymidine_" reversible="false">
17288 <notes>
17289 <html:p>GENE_ASSOCIATION: b1238</html:p>
17290 <html:p>PROTEIN_ASSOCIATION: Tdk</html:p>
17291 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
17292 <html:p>PROTEIN_CLASS: 2.7.1.21</html:p>
17293 </notes>
17294 <listOfReactants>
17295 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
17296 <speciesReference species="M_thymd_c" stoichiometry="1.000000"/>
17297 </listOfReactants>
17298 <listOfProducts>
17299 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
17300 <speciesReference species="M_dtmp_c" stoichiometry="1.000000"/>
17301 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17302 </listOfProducts>
17303 </reaction>
17304 <reaction id="R_TMDPP" name="R_thymidine_phosphorylase" reversible="true">
17305 <notes>
17306 <html:p>GENE_ASSOCIATION: b4382</html:p>
17307 <html:p>PROTEIN_ASSOCIATION: DeoA</html:p>
17308 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
17309 <html:p>PROTEIN_CLASS: 2.4.2.4</html:p>
17310 </notes>
17311 <listOfReactants>
17312 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
17313 <speciesReference species="M_thymd_c" stoichiometry="1.000000"/>
17314 </listOfReactants>
17315 <listOfProducts>
17316 <speciesReference species="M_2dr1p_c" stoichiometry="1.000000"/>
17317 <speciesReference species="M_thym_c" stoichiometry="1.000000"/>
17318 </listOfProducts>
17319 </reaction>
17320 <reaction id="R_TMDS" name="R_thymidylate_synthase" reversible="false">
17321 <notes>
17322 <html:p>GENE_ASSOCIATION: b2827</html:p>
17323 <html:p>PROTEIN_ASSOCIATION: ThyA</html:p>
17324 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
17325 <html:p>PROTEIN_CLASS: 2.1.1.45</html:p>
17326 </notes>
17327 <listOfReactants>
17328 <speciesReference species="M_dump_c" stoichiometry="1.000000"/>
17329 <speciesReference species="M_mlthf_c" stoichiometry="1.000000"/>
17330 </listOfReactants>
17331 <listOfProducts>
17332 <speciesReference species="M_dhf_c" stoichiometry="1.000000"/>
17333 <speciesReference species="M_dtmp_c" stoichiometry="1.000000"/>
17334 </listOfProducts>
17335 </reaction>
17336 <reaction id="R_TMKr" name="R_thiamine_kinase" reversible="true">
17337 <notes>
17338 <html:p>GENE_ASSOCIATION: </html:p>
17339 <html:p>PROTEIN_ASSOCIATION: </html:p>
17340 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
17341 <html:p>PROTEIN_CLASS: 2.7.1.89</html:p>
17342 </notes>
17343 <listOfReactants>
17344 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
17345 <speciesReference species="M_thm_c" stoichiometry="1.000000"/>
17346 </listOfReactants>
17347 <listOfProducts>
17348 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
17349 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17350 <speciesReference species="M_thmmp_c" stoichiometry="1.000000"/>
17351 </listOfProducts>
17352 </reaction>
17353 <reaction id="R_TMPKr" name="R_thiamine_phosphate_kinase" reversible="true">
17354 <notes>
17355 <html:p>GENE_ASSOCIATION: b0417</html:p>
17356 <html:p>PROTEIN_ASSOCIATION: ThiL</html:p>
17357 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
17358 <html:p>PROTEIN_CLASS: 2.7.4.16</html:p>
17359 </notes>
17360 <listOfReactants>
17361 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
17362 <speciesReference species="M_thmmp_c" stoichiometry="1.000000"/>
17363 </listOfReactants>
17364 <listOfProducts>
17365 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
17366 <speciesReference species="M_thmpp_c" stoichiometry="1.000000"/>
17367 </listOfProducts>
17368 </reaction>
17369 <reaction id="R_TMPPP" name="R_thiamine_phosphate_diphosphorylase" reversible="false">
17370 <notes>
17371 <html:p>GENE_ASSOCIATION: b3993</html:p>
17372 <html:p>PROTEIN_ASSOCIATION: ThiE</html:p>
17373 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
17374 <html:p>PROTEIN_CLASS: 2.5.1.3</html:p>
17375 </notes>
17376 <listOfReactants>
17377 <speciesReference species="M_2mahmp_c" stoichiometry="1.000000"/>
17378 <speciesReference species="M_4mpetz_c" stoichiometry="1.000000"/>
17379 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17380 </listOfReactants>
17381 <listOfProducts>
17382 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
17383 <speciesReference species="M_thmmp_c" stoichiometry="1.000000"/>
17384 </listOfProducts>
17385 </reaction>
17386 <reaction id="R_TPI" name="R_triose_phosphate_isomerase" reversible="true">
17387 <notes>
17388 <html:p>GENE_ASSOCIATION: b3919</html:p>
17389 <html:p>PROTEIN_ASSOCIATION: Tpi</html:p>
17390 <html:p>SUBSYSTEM: S_GlycolysisGluconeogenesis</html:p>
17391 <html:p>PROTEIN_CLASS: 5.3.1.1</html:p>
17392 </notes>
17393 <listOfReactants>
17394 <speciesReference species="M_dhap_c" stoichiometry="1.000000"/>
17395 </listOfReactants>
17396 <listOfProducts>
17397 <speciesReference species="M_g3p_c" stoichiometry="1.000000"/>
17398 </listOfProducts>
17399 </reaction>
17400 <reaction id="R_TRDR" name="R_thioredoxin_reductase__NADPH_" reversible="false">
17401 <notes>
17402 <html:p>GENE_ASSOCIATION: b0888</html:p>
17403 <html:p>PROTEIN_ASSOCIATION: TrxB</html:p>
17404 <html:p>SUBSYSTEM: S_Oxidative_Phosphorylation</html:p>
17405 <html:p>PROTEIN_CLASS: 1.8.1.9</html:p>
17406 </notes>
17407 <listOfReactants>
17408 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17409 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
17410 <speciesReference species="M_trdox_c" stoichiometry="1.000000"/>
17411 </listOfReactants>
17412 <listOfProducts>
17413 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
17414 <speciesReference species="M_trdrd_c" stoichiometry="1.000000"/>
17415 </listOfProducts>
17416 </reaction>
17417 <reaction id="R_TRE6PH" name="R_trehalose_6_phosphate_hydrolase" reversible="false">
17418 <notes>
17419 <html:p>GENE_ASSOCIATION: b4239</html:p>
17420 <html:p>PROTEIN_ASSOCIATION: TreC</html:p>
17421 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
17422 <html:p>PROTEIN_CLASS: 3.2.1.93</html:p>
17423 </notes>
17424 <listOfReactants>
17425 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
17426 <speciesReference species="M_tre6p_c" stoichiometry="1.000000"/>
17427 </listOfReactants>
17428 <listOfProducts>
17429 <speciesReference species="M_g6p_c" stoichiometry="1.000000"/>
17430 <speciesReference species="M_glc_D_c" stoichiometry="1.000000"/>
17431 </listOfProducts>
17432 </reaction>
17433 <reaction id="R_TRE6PP" name="R_trehalose_phosphatase" reversible="false">
17434 <notes>
17435 <html:p>GENE_ASSOCIATION: b1897</html:p>
17436 <html:p>PROTEIN_ASSOCIATION: OtsB</html:p>
17437 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
17438 <html:p>PROTEIN_CLASS: 3.1.3.12</html:p>
17439 </notes>
17440 <listOfReactants>
17441 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
17442 <speciesReference species="M_tre6p_c" stoichiometry="1.000000"/>
17443 </listOfReactants>
17444 <listOfProducts>
17445 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
17446 <speciesReference species="M_tre_c" stoichiometry="1.000000"/>
17447 </listOfProducts>
17448 </reaction>
17449 <reaction id="R_TRE6PS" name="R_alpha_alpha_trehalose_phosphate_synthase__UDP_forming_" reversible="false">
17450 <notes>
17451 <html:p>GENE_ASSOCIATION: b1896</html:p>
17452 <html:p>PROTEIN_ASSOCIATION: OtsA</html:p>
17453 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
17454 <html:p>PROTEIN_CLASS: 2.4.1.15</html:p>
17455 </notes>
17456 <listOfReactants>
17457 <speciesReference species="M_g6p_c" stoichiometry="1.000000"/>
17458 <speciesReference species="M_udpg_c" stoichiometry="1.000000"/>
17459 </listOfReactants>
17460 <listOfProducts>
17461 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17462 <speciesReference species="M_tre6p_c" stoichiometry="1.000000"/>
17463 <speciesReference species="M_udp_c" stoichiometry="1.000000"/>
17464 </listOfProducts>
17465 </reaction>
17466 <reaction id="R_TREH" name="R_alpha_alpha_trehalase" reversible="false">
17467 <notes>
17468 <html:p>GENE_ASSOCIATION: b3519</html:p>
17469 <html:p>PROTEIN_ASSOCIATION: TreF</html:p>
17470 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
17471 <html:p>PROTEIN_CLASS: 3.2.1.28</html:p>
17472 </notes>
17473 <listOfReactants>
17474 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
17475 <speciesReference species="M_tre_c" stoichiometry="1.000000"/>
17476 </listOfReactants>
17477 <listOfProducts>
17478 <speciesReference species="M_glc_D_c" stoichiometry="2.000000"/>
17479 </listOfProducts>
17480 </reaction>
17481 <reaction id="R_TREHe" name="R_alpha_alpha_trehalase" reversible="false">
17482 <notes>
17483 <html:p>GENE_ASSOCIATION: b1197</html:p>
17484 <html:p>PROTEIN_ASSOCIATION: TreA</html:p>
17485 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
17486 <html:p>PROTEIN_CLASS: 3.2.1.28</html:p>
17487 </notes>
17488 <listOfReactants>
17489 <speciesReference species="M_h2o_e" stoichiometry="1.000000"/>
17490 <speciesReference species="M_tre_e" stoichiometry="1.000000"/>
17491 </listOfReactants>
17492 <listOfProducts>
17493 <speciesReference species="M_glc_D_e" stoichiometry="2.000000"/>
17494 </listOfProducts>
17495 </reaction>
17496 <reaction id="R_TREpts" name="R_trehalose_transport_via_PEPPyr_PTS" reversible="false">
17497 <notes>
17498 <html:p>GENE_ASSOCIATION: ( b2417 and b2415 and b2416 and b4240 )</html:p>
17499 <html:p>PROTEIN_ASSOCIATION: ( Crr and PtsH and PtsI and TreB )</html:p>
17500 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
17501 <html:p>PROTEIN_CLASS: </html:p>
17502 </notes>
17503 <listOfReactants>
17504 <speciesReference species="M_pep_c" stoichiometry="1.000000"/>
17505 <speciesReference species="M_tre_e" stoichiometry="1.000000"/>
17506 </listOfReactants>
17507 <listOfProducts>
17508 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
17509 <speciesReference species="M_tre6p_c" stoichiometry="1.000000"/>
17510 </listOfProducts>
17511 </reaction>
17512 <reaction id="R_TRPAS2" name="R_Tryptophanase__L_tryptophan_" reversible="true">
17513 <notes>
17514 <html:p>GENE_ASSOCIATION: b3708</html:p>
17515 <html:p>PROTEIN_ASSOCIATION: TnaA</html:p>
17516 <html:p>SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism</html:p>
17517 <html:p>PROTEIN_CLASS: 4.1.99.1</html:p>
17518 </notes>
17519 <listOfReactants>
17520 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
17521 <speciesReference species="M_trp_L_c" stoichiometry="1.000000"/>
17522 </listOfReactants>
17523 <listOfProducts>
17524 <speciesReference species="M_indole_c" stoichiometry="1.000000"/>
17525 <speciesReference species="M_nh4_c" stoichiometry="1.000000"/>
17526 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
17527 </listOfProducts>
17528 </reaction>
17529 <reaction id="R_TRPS1" name="R_tryptophan_synthase__indoleglycerol_phosphate_" reversible="false">
17530 <notes>
17531 <html:p>GENE_ASSOCIATION: ( b1260 and b1261 )</html:p>
17532 <html:p>PROTEIN_ASSOCIATION: TrpA</html:p>
17533 <html:p>SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism</html:p>
17534 <html:p>PROTEIN_CLASS: 4.2.1.20</html:p>
17535 </notes>
17536 <listOfReactants>
17537 <speciesReference species="M_3ig3p_c" stoichiometry="1.000000"/>
17538 <speciesReference species="M_ser_L_c" stoichiometry="1.000000"/>
17539 </listOfReactants>
17540 <listOfProducts>
17541 <speciesReference species="M_g3p_c" stoichiometry="1.000000"/>
17542 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
17543 <speciesReference species="M_trp_L_c" stoichiometry="1.000000"/>
17544 </listOfProducts>
17545 </reaction>
17546 <reaction id="R_TRPS2" name="R_tryptophan_synthase__indole_" reversible="false">
17547 <notes>
17548 <html:p>GENE_ASSOCIATION: ( b1260 and b1261 )</html:p>
17549 <html:p>PROTEIN_ASSOCIATION: TrpA</html:p>
17550 <html:p>SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism</html:p>
17551 <html:p>PROTEIN_CLASS: 4.2.1.20</html:p>
17552 </notes>
17553 <listOfReactants>
17554 <speciesReference species="M_indole_c" stoichiometry="1.000000"/>
17555 <speciesReference species="M_ser_L_c" stoichiometry="1.000000"/>
17556 </listOfReactants>
17557 <listOfProducts>
17558 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
17559 <speciesReference species="M_trp_L_c" stoichiometry="1.000000"/>
17560 </listOfProducts>
17561 </reaction>
17562 <reaction id="R_TRPS3" name="R_tryptophan_synthase__indoleglycerol_phosphate_" reversible="false">
17563 <notes>
17564 <html:p>GENE_ASSOCIATION: ( b1260 and b1261 )</html:p>
17565 <html:p>PROTEIN_ASSOCIATION: TrpA</html:p>
17566 <html:p>SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism</html:p>
17567 <html:p>PROTEIN_CLASS: 4.2.1.20</html:p>
17568 </notes>
17569 <listOfReactants>
17570 <speciesReference species="M_3ig3p_c" stoichiometry="1.000000"/>
17571 </listOfReactants>
17572 <listOfProducts>
17573 <speciesReference species="M_g3p_c" stoichiometry="1.000000"/>
17574 <speciesReference species="M_indole_c" stoichiometry="1.000000"/>
17575 </listOfProducts>
17576 </reaction>
17577 <reaction id="R_TRPt2r" name="R_L_tryptophan_reversible_transport_via_proton_symport" reversible="true">
17578 <notes>
17579 <html:p>GENE_ASSOCIATION: ( b3709 or b0112 or b3161 )</html:p>
17580 <html:p>PROTEIN_ASSOCIATION: ( TnaB ) or ( AroP ) or ( Mtr )</html:p>
17581 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
17582 <html:p>PROTEIN_CLASS: </html:p>
17583 </notes>
17584 <listOfReactants>
17585 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
17586 <speciesReference species="M_trp_L_e" stoichiometry="1.000000"/>
17587 </listOfReactants>
17588 <listOfProducts>
17589 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17590 <speciesReference species="M_trp_L_c" stoichiometry="1.000000"/>
17591 </listOfProducts>
17592 </reaction>
17593 <reaction id="R_TRSAR" name="R_tartronate_semialdehyde_reductase" reversible="false">
17594 <notes>
17595 <html:p>GENE_ASSOCIATION: ( b3125 or b0509 )</html:p>
17596 <html:p>PROTEIN_ASSOCIATION: ( GarR ) or ( GlxR )</html:p>
17597 <html:p>SUBSYSTEM: S_Glyoxylate_Metabolism</html:p>
17598 <html:p>PROTEIN_CLASS: 1.1.1.60</html:p>
17599 </notes>
17600 <listOfReactants>
17601 <speciesReference species="M_2h3oppan_c" stoichiometry="1.000000"/>
17602 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17603 <speciesReference species="M_nadh_c" stoichiometry="1.000000"/>
17604 </listOfReactants>
17605 <listOfProducts>
17606 <speciesReference species="M_glyc_R_c" stoichiometry="1.000000"/>
17607 <speciesReference species="M_nad_c" stoichiometry="1.000000"/>
17608 </listOfProducts>
17609 </reaction>
17610 <reaction id="R_TSULabc" name="R_thiosulfate_transport_via_ABC_system" reversible="false">
17611 <notes>
17612 <html:p>GENE_ASSOCIATION: ( ( b2422 and b2424 and b2423 and b3917 ) or ( b2422 and b2425 and b2424 and b2423 ) )</html:p>
17613 <html:p>PROTEIN_ASSOCIATION: ( CysA and CysU and CysW and Sbp ) or ( CysA and CysP and CysU and CysW )</html:p>
17614 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
17615 <html:p>PROTEIN_CLASS: </html:p>
17616 </notes>
17617 <listOfReactants>
17618 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
17619 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
17620 <speciesReference species="M_tsul_e" stoichiometry="1.000000"/>
17621 </listOfReactants>
17622 <listOfProducts>
17623 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
17624 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17625 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
17626 <speciesReference species="M_tsul_c" stoichiometry="1.000000"/>
17627 </listOfProducts>
17628 </reaction>
17629 <reaction id="R_TTDCAt2" name="R_Tetradecanoate_transport_via_proton_symport" reversible="false">
17630 <notes>
17631 <html:p>GENE_ASSOCIATION: b2344</html:p>
17632 <html:p>PROTEIN_ASSOCIATION: FadL</html:p>
17633 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
17634 <html:p>PROTEIN_CLASS: </html:p>
17635 </notes>
17636 <listOfReactants>
17637 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
17638 <speciesReference species="M_ttdca_e" stoichiometry="1.000000"/>
17639 </listOfReactants>
17640 <listOfProducts>
17641 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17642 <speciesReference species="M_ttdca_c" stoichiometry="1.000000"/>
17643 </listOfProducts>
17644 </reaction>
17645 <reaction id="R_TYRTA" name="R_tyrosine_transaminase" reversible="true">
17646 <notes>
17647 <html:p>GENE_ASSOCIATION: ( b4054 or b0928 )</html:p>
17648 <html:p>PROTEIN_ASSOCIATION: ( TyrB ) or ( AspC )</html:p>
17649 <html:p>SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism</html:p>
17650 <html:p>PROTEIN_CLASS: 2.6.1.5</html:p>
17651 </notes>
17652 <listOfReactants>
17653 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
17654 <speciesReference species="M_tyr_L_c" stoichiometry="1.000000"/>
17655 </listOfReactants>
17656 <listOfProducts>
17657 <speciesReference species="M_34hpp_c" stoichiometry="1.000000"/>
17658 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
17659 </listOfProducts>
17660 </reaction>
17661 <reaction id="R_TYRt2r" name="R_L_tyrosine_reversible_transport_via_proton_symport" reversible="true">
17662 <notes>
17663 <html:p>GENE_ASSOCIATION: ( b1907 or b0576 or b0112 )</html:p>
17664 <html:p>PROTEIN_ASSOCIATION: ( TyrP ) or ( PheP ) or ( AroP )</html:p>
17665 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
17666 <html:p>PROTEIN_CLASS: </html:p>
17667 </notes>
17668 <listOfReactants>
17669 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
17670 <speciesReference species="M_tyr_L_e" stoichiometry="1.000000"/>
17671 </listOfReactants>
17672 <listOfProducts>
17673 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17674 <speciesReference species="M_tyr_L_c" stoichiometry="1.000000"/>
17675 </listOfProducts>
17676 </reaction>
17677 <reaction id="R_U23GAAT" name="R_UDP_3_O__3_hydroxymyristoyl_glucosamine_acyltransferase" reversible="false">
17678 <notes>
17679 <html:p>GENE_ASSOCIATION: b0179</html:p>
17680 <html:p>PROTEIN_ASSOCIATION: LpxD</html:p>
17681 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
17682 <html:p>PROTEIN_CLASS: </html:p>
17683 </notes>
17684 <listOfReactants>
17685 <speciesReference species="M_3hmrsACP_c" stoichiometry="1.000000"/>
17686 <speciesReference species="M_u3hga_c" stoichiometry="1.000000"/>
17687 </listOfReactants>
17688 <listOfProducts>
17689 <speciesReference species="M_ACP_c" stoichiometry="1.000000"/>
17690 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17691 <speciesReference species="M_u23ga_c" stoichiometry="1.000000"/>
17692 </listOfProducts>
17693 </reaction>
17694 <reaction id="R_UAAGDS" name="R_UDP_N_acetylmuramoyl_L_alanyl_D_glutamyl_meso_2_6_diaminopimelate_synthetase" reversible="false">
17695 <notes>
17696 <html:p>GENE_ASSOCIATION: b0085</html:p>
17697 <html:p>PROTEIN_ASSOCIATION: MurEec</html:p>
17698 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
17699 <html:p>PROTEIN_CLASS: 6.3.2.13</html:p>
17700 </notes>
17701 <listOfReactants>
17702 <speciesReference species="M_26dap_M_c" stoichiometry="1.000000"/>
17703 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
17704 <speciesReference species="M_uamag_c" stoichiometry="1.000000"/>
17705 </listOfReactants>
17706 <listOfProducts>
17707 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
17708 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17709 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
17710 <speciesReference species="M_ugmd_c" stoichiometry="1.000000"/>
17711 </listOfProducts>
17712 </reaction>
17713 <reaction id="R_UACMAMO" name="R_UDP_N_acetyl_D_mannosamine_oxidoreductase" reversible="false">
17714 <notes>
17715 <html:p>GENE_ASSOCIATION: b3787</html:p>
17716 <html:p>PROTEIN_ASSOCIATION: WecC</html:p>
17717 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
17718 <html:p>PROTEIN_CLASS: </html:p>
17719 </notes>
17720 <listOfReactants>
17721 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
17722 <speciesReference species="M_nad_c" stoichiometry="2.000000"/>
17723 <speciesReference species="M_uacmam_c" stoichiometry="1.000000"/>
17724 </listOfReactants>
17725 <listOfProducts>
17726 <speciesReference species="M_h_c" stoichiometry="3.000000"/>
17727 <speciesReference species="M_nadh_c" stoichiometry="2.000000"/>
17728 <speciesReference species="M_uacmamu_c" stoichiometry="1.000000"/>
17729 </listOfProducts>
17730 </reaction>
17731 <reaction id="R_UAG2Ei" name="R_UDP_N_acetylglucosamine_2_epimerase" reversible="false">
17732 <notes>
17733 <html:p>GENE_ASSOCIATION: b3786</html:p>
17734 <html:p>PROTEIN_ASSOCIATION: WecB</html:p>
17735 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
17736 <html:p>PROTEIN_CLASS: 5.1.3.14</html:p>
17737 </notes>
17738 <listOfReactants>
17739 <speciesReference species="M_uacgam_c" stoichiometry="1.000000"/>
17740 </listOfReactants>
17741 <listOfProducts>
17742 <speciesReference species="M_uacmam_c" stoichiometry="1.000000"/>
17743 </listOfProducts>
17744 </reaction>
17745 <reaction id="R_UAGAAT" name="R_UDP_N_acetylglucosamine_acyltransferase" reversible="true">
17746 <notes>
17747 <html:p>GENE_ASSOCIATION: b0181</html:p>
17748 <html:p>PROTEIN_ASSOCIATION: LpxA</html:p>
17749 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
17750 <html:p>PROTEIN_CLASS: 2.3.1.129</html:p>
17751 </notes>
17752 <listOfReactants>
17753 <speciesReference species="M_3hmrsACP_c" stoichiometry="1.000000"/>
17754 <speciesReference species="M_uacgam_c" stoichiometry="1.000000"/>
17755 </listOfReactants>
17756 <listOfProducts>
17757 <speciesReference species="M_ACP_c" stoichiometry="1.000000"/>
17758 <speciesReference species="M_u3aga_c" stoichiometry="1.000000"/>
17759 </listOfProducts>
17760 </reaction>
17761 <reaction id="R_UAGCVT" name="R_UDP_N_acetylglucosamine_1_carboxyvinyltransferase" reversible="false">
17762 <notes>
17763 <html:p>GENE_ASSOCIATION: b3189</html:p>
17764 <html:p>PROTEIN_ASSOCIATION: MurA</html:p>
17765 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
17766 <html:p>PROTEIN_CLASS: 2.5.1.7</html:p>
17767 </notes>
17768 <listOfReactants>
17769 <speciesReference species="M_pep_c" stoichiometry="1.000000"/>
17770 <speciesReference species="M_uacgam_c" stoichiometry="1.000000"/>
17771 </listOfReactants>
17772 <listOfProducts>
17773 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
17774 <speciesReference species="M_uaccg_c" stoichiometry="1.000000"/>
17775 </listOfProducts>
17776 </reaction>
17777 <reaction id="R_UAGDP" name="R_UDP_N_acetylglucosamine_diphosphorylase" reversible="false">
17778 <notes>
17779 <html:p>GENE_ASSOCIATION: b3730</html:p>
17780 <html:p>PROTEIN_ASSOCIATION: GlmUec</html:p>
17781 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
17782 <html:p>PROTEIN_CLASS: 2.7.7.23</html:p>
17783 </notes>
17784 <listOfReactants>
17785 <speciesReference species="M_acgam1p_c" stoichiometry="1.000000"/>
17786 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17787 <speciesReference species="M_utp_c" stoichiometry="1.000000"/>
17788 </listOfReactants>
17789 <listOfProducts>
17790 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
17791 <speciesReference species="M_uacgam_c" stoichiometry="1.000000"/>
17792 </listOfProducts>
17793 </reaction>
17794 <reaction id="R_UAGPT3" name="R_UDP_N_acetylglucosamine_N_acetylmuramyl__pentapeptide_pyrophosphoryl_undecaprenol_N_acetylglucosamine_transferase" reversible="false">
17795 <notes>
17796 <html:p>GENE_ASSOCIATION: b0090</html:p>
17797 <html:p>PROTEIN_ASSOCIATION: MurGec</html:p>
17798 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
17799 <html:p>PROTEIN_CLASS: </html:p>
17800 </notes>
17801 <listOfReactants>
17802 <speciesReference species="M_uacgam_c" stoichiometry="1.000000"/>
17803 <speciesReference species="M_uagmda_c" stoichiometry="1.000000"/>
17804 </listOfReactants>
17805 <listOfProducts>
17806 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17807 <speciesReference species="M_uaagmda_c" stoichiometry="1.000000"/>
17808 <speciesReference species="M_udp_c" stoichiometry="1.000000"/>
17809 </listOfProducts>
17810 </reaction>
17811 <reaction id="R_UAMAGS" name="R_UDP_N_acetylmuramoyl_L_alanyl_D_glutamate_synthetase" reversible="false">
17812 <notes>
17813 <html:p>GENE_ASSOCIATION: b0088</html:p>
17814 <html:p>PROTEIN_ASSOCIATION: MurD</html:p>
17815 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
17816 <html:p>PROTEIN_CLASS: 6.3.2.9</html:p>
17817 </notes>
17818 <listOfReactants>
17819 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
17820 <speciesReference species="M_glu_D_c" stoichiometry="1.000000"/>
17821 <speciesReference species="M_uama_c" stoichiometry="1.000000"/>
17822 </listOfReactants>
17823 <listOfProducts>
17824 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
17825 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17826 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
17827 <speciesReference species="M_uamag_c" stoichiometry="1.000000"/>
17828 </listOfProducts>
17829 </reaction>
17830 <reaction id="R_UAMAS" name="R_UDP_N_acetylmuramoyl_L_alanine_synthetase" reversible="false">
17831 <notes>
17832 <html:p>GENE_ASSOCIATION: b0091</html:p>
17833 <html:p>PROTEIN_ASSOCIATION: MurC</html:p>
17834 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
17835 <html:p>PROTEIN_CLASS: 6.3.2.8</html:p>
17836 </notes>
17837 <listOfReactants>
17838 <speciesReference species="M_ala_L_c" stoichiometry="1.000000"/>
17839 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
17840 <speciesReference species="M_uamr_c" stoichiometry="1.000000"/>
17841 </listOfReactants>
17842 <listOfProducts>
17843 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
17844 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17845 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
17846 <speciesReference species="M_uama_c" stoichiometry="1.000000"/>
17847 </listOfProducts>
17848 </reaction>
17849 <reaction id="R_UAPGR" name="R_UDP_N_acetylenolpyruvoylglucosamine_reductase" reversible="false">
17850 <notes>
17851 <html:p>GENE_ASSOCIATION: b3972</html:p>
17852 <html:p>PROTEIN_ASSOCIATION: MurB</html:p>
17853 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
17854 <html:p>PROTEIN_CLASS: 1.1.1.158</html:p>
17855 </notes>
17856 <listOfReactants>
17857 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17858 <speciesReference species="M_nadph_c" stoichiometry="1.000000"/>
17859 <speciesReference species="M_uaccg_c" stoichiometry="1.000000"/>
17860 </listOfReactants>
17861 <listOfProducts>
17862 <speciesReference species="M_nadp_c" stoichiometry="1.000000"/>
17863 <speciesReference species="M_uamr_c" stoichiometry="1.000000"/>
17864 </listOfProducts>
17865 </reaction>
17866 <reaction id="R_UDCPDP" name="R_undecaprenyl_diphosphatase" reversible="false">
17867 <notes>
17868 <html:p>GENE_ASSOCIATION: </html:p>
17869 <html:p>PROTEIN_ASSOCIATION: </html:p>
17870 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
17871 <html:p>PROTEIN_CLASS: 3.6.1.27</html:p>
17872 </notes>
17873 <listOfReactants>
17874 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
17875 <speciesReference species="M_udcpdp_c" stoichiometry="1.000000"/>
17876 </listOfReactants>
17877 <listOfProducts>
17878 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17879 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
17880 <speciesReference species="M_udcpp_c" stoichiometry="1.000000"/>
17881 </listOfProducts>
17882 </reaction>
17883 <reaction id="R_UDCPDPS" name="R_Undecaprenyl_diphosphate_synthase" reversible="false">
17884 <notes>
17885 <html:p>GENE_ASSOCIATION: b0174</html:p>
17886 <html:p>PROTEIN_ASSOCIATION: UppS</html:p>
17887 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
17888 <html:p>PROTEIN_CLASS: </html:p>
17889 </notes>
17890 <listOfReactants>
17891 <speciesReference species="M_frdp_c" stoichiometry="1.000000"/>
17892 <speciesReference species="M_ipdp_c" stoichiometry="8.000000"/>
17893 </listOfReactants>
17894 <listOfProducts>
17895 <speciesReference species="M_ppi_c" stoichiometry="8.000000"/>
17896 <speciesReference species="M_udcpdp_c" stoichiometry="1.000000"/>
17897 </listOfProducts>
17898 </reaction>
17899 <reaction id="R_UDPG4E" name="R_UDPglucose_4_epimerase" reversible="true">
17900 <notes>
17901 <html:p>GENE_ASSOCIATION: b0759</html:p>
17902 <html:p>PROTEIN_ASSOCIATION: GalE</html:p>
17903 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
17904 <html:p>PROTEIN_CLASS: 5.1.3.2</html:p>
17905 </notes>
17906 <listOfReactants>
17907 <speciesReference species="M_udpg_c" stoichiometry="1.000000"/>
17908 </listOfReactants>
17909 <listOfProducts>
17910 <speciesReference species="M_udpgal_c" stoichiometry="1.000000"/>
17911 </listOfProducts>
17912 </reaction>
17913 <reaction id="R_UDPGALM" name="R_UDPgalactopyranose_mutase" reversible="false">
17914 <notes>
17915 <html:p>GENE_ASSOCIATION: b2036</html:p>
17916 <html:p>PROTEIN_ASSOCIATION: Glf</html:p>
17917 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
17918 <html:p>PROTEIN_CLASS: 5.4.99.9</html:p>
17919 </notes>
17920 <listOfReactants>
17921 <speciesReference species="M_udpgal_c" stoichiometry="1.000000"/>
17922 </listOfReactants>
17923 <listOfProducts>
17924 <speciesReference species="M_udpgalfur_c" stoichiometry="1.000000"/>
17925 </listOfProducts>
17926 </reaction>
17927 <reaction id="R_UDPGD" name="R_UDPglucose_6_dehydrogenase" reversible="false">
17928 <notes>
17929 <html:p>GENE_ASSOCIATION: b2028</html:p>
17930 <html:p>PROTEIN_ASSOCIATION: Ugd</html:p>
17931 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
17932 <html:p>PROTEIN_CLASS: 1.1.1.22</html:p>
17933 </notes>
17934 <listOfReactants>
17935 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
17936 <speciesReference species="M_nad_c" stoichiometry="2.000000"/>
17937 <speciesReference species="M_udpg_c" stoichiometry="1.000000"/>
17938 </listOfReactants>
17939 <listOfProducts>
17940 <speciesReference species="M_h_c" stoichiometry="3.000000"/>
17941 <speciesReference species="M_nadh_c" stoichiometry="2.000000"/>
17942 <speciesReference species="M_udpglcur_c" stoichiometry="1.000000"/>
17943 </listOfProducts>
17944 </reaction>
17945 <reaction id="R_UGLT" name="R_UDPglucose__hexose_1_phosphate_uridylyltransferase" reversible="true">
17946 <notes>
17947 <html:p>GENE_ASSOCIATION: b0758</html:p>
17948 <html:p>PROTEIN_ASSOCIATION: GalT</html:p>
17949 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
17950 <html:p>PROTEIN_CLASS: 2.7.7.12</html:p>
17951 </notes>
17952 <listOfReactants>
17953 <speciesReference species="M_gal1p_c" stoichiometry="1.000000"/>
17954 <speciesReference species="M_udpg_c" stoichiometry="1.000000"/>
17955 </listOfReactants>
17956 <listOfProducts>
17957 <speciesReference species="M_g1p_c" stoichiometry="1.000000"/>
17958 <speciesReference species="M_udpgal_c" stoichiometry="1.000000"/>
17959 </listOfProducts>
17960 </reaction>
17961 <reaction id="R_UGLYCH" name="R_Ureidoglycolate_hydrolase" reversible="false">
17962 <notes>
17963 <html:p>GENE_ASSOCIATION: b0505</html:p>
17964 <html:p>PROTEIN_ASSOCIATION: AllA</html:p>
17965 <html:p>SUBSYSTEM: S_Nitrogen_Metabolism</html:p>
17966 <html:p>PROTEIN_CLASS: 3.5.3.19</html:p>
17967 </notes>
17968 <listOfReactants>
17969 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
17970 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
17971 <speciesReference species="M_urdglyc_c" stoichiometry="1.000000"/>
17972 </listOfReactants>
17973 <listOfProducts>
17974 <speciesReference species="M_co2_c" stoichiometry="1.000000"/>
17975 <speciesReference species="M_glx_c" stoichiometry="1.000000"/>
17976 <speciesReference species="M_nh4_c" stoichiometry="2.000000"/>
17977 </listOfProducts>
17978 </reaction>
17979 <reaction id="R_UGMDDS" name="R_UDP_N_acetylmuramoyl_L_alanyl_D_glutamyl_meso_2_6_diaminopimeloyl_D_alanyl_D_alanine_synthetase" reversible="false">
17980 <notes>
17981 <html:p>GENE_ASSOCIATION: b0086</html:p>
17982 <html:p>PROTEIN_ASSOCIATION: MurFec</html:p>
17983 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
17984 <html:p>PROTEIN_CLASS: 6.3.2.15</html:p>
17985 </notes>
17986 <listOfReactants>
17987 <speciesReference species="M_alaala_c" stoichiometry="1.000000"/>
17988 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
17989 <speciesReference species="M_ugmd_c" stoichiometry="1.000000"/>
17990 </listOfReactants>
17991 <listOfProducts>
17992 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
17993 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
17994 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
17995 <speciesReference species="M_ugmda_c" stoichiometry="1.000000"/>
17996 </listOfProducts>
17997 </reaction>
17998 <reaction id="R_UHGADA" name="R_UDP_3_O_acetylglucosamine_deacetylase" reversible="false">
17999 <notes>
18000 <html:p>GENE_ASSOCIATION: b0096</html:p>
18001 <html:p>PROTEIN_ASSOCIATION: LpxC</html:p>
18002 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
18003 <html:p>PROTEIN_CLASS: </html:p>
18004 </notes>
18005 <listOfReactants>
18006 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
18007 <speciesReference species="M_u3aga_c" stoichiometry="1.000000"/>
18008 </listOfReactants>
18009 <listOfProducts>
18010 <speciesReference species="M_ac_c" stoichiometry="1.000000"/>
18011 <speciesReference species="M_u3hga_c" stoichiometry="1.000000"/>
18012 </listOfProducts>
18013 </reaction>
18014 <reaction id="R_UMPK" name="R_UMP_kinase" reversible="true">
18015 <notes>
18016 <html:p>GENE_ASSOCIATION: ( b0910 or b0171 )</html:p>
18017 <html:p>PROTEIN_ASSOCIATION: ( Cmk ) or ( PyrHec )</html:p>
18018 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
18019 <html:p>PROTEIN_CLASS: 2.7.4.14</html:p>
18020 </notes>
18021 <listOfReactants>
18022 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
18023 <speciesReference species="M_ump_c" stoichiometry="1.000000"/>
18024 </listOfReactants>
18025 <listOfProducts>
18026 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
18027 <speciesReference species="M_udp_c" stoichiometry="1.000000"/>
18028 </listOfProducts>
18029 </reaction>
18030 <reaction id="R_UNK3" name="R_2_keto_4_methylthiobutyrate_transamination" reversible="false">
18031 <notes>
18032 <html:p>GENE_ASSOCIATION: </html:p>
18033 <html:p>PROTEIN_ASSOCIATION: </html:p>
18034 <html:p>SUBSYSTEM: S_Arginine_and_Proline_Metabolism</html:p>
18035 <html:p>PROTEIN_CLASS: </html:p>
18036 </notes>
18037 <listOfReactants>
18038 <speciesReference species="M_2kmb_c" stoichiometry="1.000000"/>
18039 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
18040 </listOfReactants>
18041 <listOfProducts>
18042 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
18043 <speciesReference species="M_met_L_c" stoichiometry="1.000000"/>
18044 </listOfProducts>
18045 </reaction>
18046 <reaction id="R_UPP3MT" name="R_uroporphyrinogen_methyltransferase" reversible="false">
18047 <notes>
18048 <html:p>GENE_ASSOCIATION: ( b3803 or b3368 )</html:p>
18049 <html:p>PROTEIN_ASSOCIATION: ( HemX ) or ( CysG )</html:p>
18050 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
18051 <html:p>PROTEIN_CLASS: 2.1.1.107</html:p>
18052 </notes>
18053 <listOfReactants>
18054 <speciesReference species="M_amet_c" stoichiometry="2.000000"/>
18055 <speciesReference species="M_uppg3_c" stoichiometry="1.000000"/>
18056 </listOfReactants>
18057 <listOfProducts>
18058 <speciesReference species="M_ahcys_c" stoichiometry="2.000000"/>
18059 <speciesReference species="M_dscl_c" stoichiometry="1.000000"/>
18060 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
18061 </listOfProducts>
18062 </reaction>
18063 <reaction id="R_UPP3S" name="R_uroporphyrinogen_III_synthase" reversible="false">
18064 <notes>
18065 <html:p>GENE_ASSOCIATION: b3804</html:p>
18066 <html:p>PROTEIN_ASSOCIATION: HemDec</html:p>
18067 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
18068 <html:p>PROTEIN_CLASS: 4.2.1.75</html:p>
18069 </notes>
18070 <listOfReactants>
18071 <speciesReference species="M_hmbil_c" stoichiometry="1.000000"/>
18072 </listOfReactants>
18073 <listOfProducts>
18074 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
18075 <speciesReference species="M_uppg3_c" stoichiometry="1.000000"/>
18076 </listOfProducts>
18077 </reaction>
18078 <reaction id="R_UPPDC1" name="R_uroporphyrinogen_decarboxylase__uroporphyrinogen_III_" reversible="false">
18079 <notes>
18080 <html:p>GENE_ASSOCIATION: b3997</html:p>
18081 <html:p>PROTEIN_ASSOCIATION: HemE</html:p>
18082 <html:p>SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis</html:p>
18083 <html:p>PROTEIN_CLASS: 4.1.1.37</html:p>
18084 </notes>
18085 <listOfReactants>
18086 <speciesReference species="M_h_c" stoichiometry="4.000000"/>
18087 <speciesReference species="M_uppg3_c" stoichiometry="1.000000"/>
18088 </listOfReactants>
18089 <listOfProducts>
18090 <speciesReference species="M_co2_c" stoichiometry="4.000000"/>
18091 <speciesReference species="M_cpppg3_c" stoichiometry="1.000000"/>
18092 </listOfProducts>
18093 </reaction>
18094 <reaction id="R_UPPRT" name="R_uracil_phosphoribosyltransferase" reversible="false">
18095 <notes>
18096 <html:p>GENE_ASSOCIATION: b2498</html:p>
18097 <html:p>PROTEIN_ASSOCIATION: Upp</html:p>
18098 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
18099 <html:p>PROTEIN_CLASS: 2.4.2.9</html:p>
18100 </notes>
18101 <listOfReactants>
18102 <speciesReference species="M_prpp_c" stoichiometry="1.000000"/>
18103 <speciesReference species="M_ura_c" stoichiometry="1.000000"/>
18104 </listOfReactants>
18105 <listOfProducts>
18106 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
18107 <speciesReference species="M_ump_c" stoichiometry="1.000000"/>
18108 </listOfProducts>
18109 </reaction>
18110 <reaction id="R_URAt2" name="R_uracil_transport_in_via_proton_symport" reversible="false">
18111 <notes>
18112 <html:p>GENE_ASSOCIATION: b2497</html:p>
18113 <html:p>PROTEIN_ASSOCIATION: UraA</html:p>
18114 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
18115 <html:p>PROTEIN_CLASS: </html:p>
18116 </notes>
18117 <listOfReactants>
18118 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
18119 <speciesReference species="M_ura_e" stoichiometry="1.000000"/>
18120 </listOfReactants>
18121 <listOfProducts>
18122 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
18123 <speciesReference species="M_ura_c" stoichiometry="1.000000"/>
18124 </listOfProducts>
18125 </reaction>
18126 <reaction id="R_URAt2r" name="R_uracil_transport_in_via_proton_symport__reversible" reversible="true">
18127 <notes>
18128 <html:p>GENE_ASSOCIATION: b1006</html:p>
18129 <html:p>PROTEIN_ASSOCIATION: YcdG</html:p>
18130 <html:p>SUBSYSTEM: S_Putative_Transporters</html:p>
18131 <html:p>PROTEIN_CLASS: </html:p>
18132 </notes>
18133 <listOfReactants>
18134 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
18135 <speciesReference species="M_ura_e" stoichiometry="1.000000"/>
18136 </listOfReactants>
18137 <listOfProducts>
18138 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
18139 <speciesReference species="M_ura_c" stoichiometry="1.000000"/>
18140 </listOfProducts>
18141 </reaction>
18142 <reaction id="R_UREAt" name="R_Urea_transport_via_facilitate_diffusion" reversible="true">
18143 <notes>
18144 <html:p>GENE_ASSOCIATION: b3927</html:p>
18145 <html:p>PROTEIN_ASSOCIATION: GlpF</html:p>
18146 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
18147 <html:p>PROTEIN_CLASS: </html:p>
18148 </notes>
18149 <listOfReactants>
18150 <speciesReference species="M_urea_e" stoichiometry="1.000000"/>
18151 </listOfReactants>
18152 <listOfProducts>
18153 <speciesReference species="M_urea_c" stoichiometry="1.000000"/>
18154 </listOfProducts>
18155 </reaction>
18156 <reaction id="R_URIDK2r" name="R_uridylate_kinase__dUMP_" reversible="true">
18157 <notes>
18158 <html:p>GENE_ASSOCIATION: b0171</html:p>
18159 <html:p>PROTEIN_ASSOCIATION: PyrHec</html:p>
18160 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
18161 <html:p>PROTEIN_CLASS: </html:p>
18162 </notes>
18163 <listOfReactants>
18164 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
18165 <speciesReference species="M_dump_c" stoichiometry="1.000000"/>
18166 </listOfReactants>
18167 <listOfProducts>
18168 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
18169 <speciesReference species="M_dudp_c" stoichiometry="1.000000"/>
18170 </listOfProducts>
18171 </reaction>
18172 <reaction id="R_URIK2" name="R_uridine_kinase__GTPUridine_" reversible="false">
18173 <notes>
18174 <html:p>GENE_ASSOCIATION: b2066</html:p>
18175 <html:p>PROTEIN_ASSOCIATION: Udk</html:p>
18176 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
18177 <html:p>PROTEIN_CLASS: 2.7.1.48</html:p>
18178 </notes>
18179 <listOfReactants>
18180 <speciesReference species="M_gtp_c" stoichiometry="1.000000"/>
18181 <speciesReference species="M_uri_c" stoichiometry="1.000000"/>
18182 </listOfReactants>
18183 <listOfProducts>
18184 <speciesReference species="M_gdp_c" stoichiometry="1.000000"/>
18185 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
18186 <speciesReference species="M_ump_c" stoichiometry="1.000000"/>
18187 </listOfProducts>
18188 </reaction>
18189 <reaction id="R_URIt2" name="R_uridine_transport_in_via_proton_symport" reversible="false">
18190 <notes>
18191 <html:p>GENE_ASSOCIATION: ( b2964 or b2393 )</html:p>
18192 <html:p>PROTEIN_ASSOCIATION: ( NupG ) or ( NupCec )</html:p>
18193 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
18194 <html:p>PROTEIN_CLASS: </html:p>
18195 </notes>
18196 <listOfReactants>
18197 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
18198 <speciesReference species="M_uri_e" stoichiometry="1.000000"/>
18199 </listOfReactants>
18200 <listOfProducts>
18201 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
18202 <speciesReference species="M_uri_c" stoichiometry="1.000000"/>
18203 </listOfProducts>
18204 </reaction>
18205 <reaction id="R_URIt2r" name="R_uridine_transport_in_via_proton_symport__reversible" reversible="true">
18206 <notes>
18207 <html:p>GENE_ASSOCIATION: b2406</html:p>
18208 <html:p>PROTEIN_ASSOCIATION: XapB</html:p>
18209 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
18210 <html:p>PROTEIN_CLASS: </html:p>
18211 </notes>
18212 <listOfReactants>
18213 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
18214 <speciesReference species="M_uri_e" stoichiometry="1.000000"/>
18215 </listOfReactants>
18216 <listOfProducts>
18217 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
18218 <speciesReference species="M_uri_c" stoichiometry="1.000000"/>
18219 </listOfProducts>
18220 </reaction>
18221 <reaction id="R_USHD" name="R_UDP_sugar_hydrolase" reversible="false">
18222 <notes>
18223 <html:p>GENE_ASSOCIATION: b0480</html:p>
18224 <html:p>PROTEIN_ASSOCIATION: UshA</html:p>
18225 <html:p>SUBSYSTEM: S_Cell_Envelope_Biosynthesis</html:p>
18226 <html:p>PROTEIN_CLASS: </html:p>
18227 </notes>
18228 <listOfReactants>
18229 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
18230 <speciesReference species="M_u23ga_c" stoichiometry="1.000000"/>
18231 </listOfReactants>
18232 <listOfProducts>
18233 <speciesReference species="M_h_c" stoichiometry="2.000000"/>
18234 <speciesReference species="M_lipidX_c" stoichiometry="1.000000"/>
18235 <speciesReference species="M_ump_c" stoichiometry="1.000000"/>
18236 </listOfProducts>
18237 </reaction>
18238 <reaction id="R_VALTA" name="R_valine_transaminase" reversible="true">
18239 <notes>
18240 <html:p>GENE_ASSOCIATION: b3770</html:p>
18241 <html:p>PROTEIN_ASSOCIATION: IlvE</html:p>
18242 <html:p>SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism</html:p>
18243 <html:p>PROTEIN_CLASS: 2.6.1.42</html:p>
18244 </notes>
18245 <listOfReactants>
18246 <speciesReference species="M_akg_c" stoichiometry="1.000000"/>
18247 <speciesReference species="M_val_L_c" stoichiometry="1.000000"/>
18248 </listOfReactants>
18249 <listOfProducts>
18250 <speciesReference species="M_3mob_c" stoichiometry="1.000000"/>
18251 <speciesReference species="M_glu_L_c" stoichiometry="1.000000"/>
18252 </listOfProducts>
18253 </reaction>
18254 <reaction id="R_VALabc" name="R_L_valine_transport_via_ABC_system" reversible="false">
18255 <notes>
18256 <html:p>GENE_ASSOCIATION: ( b3454 and b3455 and b3457 and b3460 and b3456 )</html:p>
18257 <html:p>PROTEIN_ASSOCIATION: ( LivF and LivG and LivH and LivJ and LivM )</html:p>
18258 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
18259 <html:p>PROTEIN_CLASS: </html:p>
18260 </notes>
18261 <listOfReactants>
18262 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
18263 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
18264 <speciesReference species="M_val_L_e" stoichiometry="1.000000"/>
18265 </listOfReactants>
18266 <listOfProducts>
18267 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
18268 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
18269 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
18270 <speciesReference species="M_val_L_c" stoichiometry="1.000000"/>
18271 </listOfProducts>
18272 </reaction>
18273 <reaction id="R_VALt2r" name="R_L_valine_reversible_transport_via_proton_symport" reversible="true">
18274 <notes>
18275 <html:p>GENE_ASSOCIATION: b0401</html:p>
18276 <html:p>PROTEIN_ASSOCIATION: BrnQ</html:p>
18277 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
18278 <html:p>PROTEIN_CLASS: </html:p>
18279 </notes>
18280 <listOfReactants>
18281 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
18282 <speciesReference species="M_val_L_e" stoichiometry="1.000000"/>
18283 </listOfReactants>
18284 <listOfProducts>
18285 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
18286 <speciesReference species="M_val_L_c" stoichiometry="1.000000"/>
18287 </listOfProducts>
18288 </reaction>
18289 <reaction id="R_VPAMT" name="R_Valine_pyruvate_aminotransferase" reversible="false">
18290 <notes>
18291 <html:p>GENE_ASSOCIATION: b3572</html:p>
18292 <html:p>PROTEIN_ASSOCIATION: AvtA</html:p>
18293 <html:p>SUBSYSTEM: S_Alanine_and_Aspartate_Metabolism</html:p>
18294 <html:p>PROTEIN_CLASS: 2.6.1.66</html:p>
18295 </notes>
18296 <listOfReactants>
18297 <speciesReference species="M_3mob_c" stoichiometry="1.000000"/>
18298 <speciesReference species="M_ala_L_c" stoichiometry="1.000000"/>
18299 </listOfReactants>
18300 <listOfProducts>
18301 <speciesReference species="M_pyr_c" stoichiometry="1.000000"/>
18302 <speciesReference species="M_val_L_c" stoichiometry="1.000000"/>
18303 </listOfProducts>
18304 </reaction>
18305 <reaction id="R_X5PL3E" name="R_L_xylulose_5_phosphate_3_epimerase" reversible="false">
18306 <notes>
18307 <html:p>GENE_ASSOCIATION: b4197</html:p>
18308 <html:p>PROTEIN_ASSOCIATION: SgaU</html:p>
18309 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
18310 <html:p>PROTEIN_CLASS: </html:p>
18311 </notes>
18312 <listOfReactants>
18313 <speciesReference species="M_xu5p_L_c" stoichiometry="1.000000"/>
18314 </listOfReactants>
18315 <listOfProducts>
18316 <speciesReference species="M_ru5p_L_c" stoichiometry="1.000000"/>
18317 </listOfProducts>
18318 </reaction>
18319 <reaction id="R_XANt" name="R_xanthine_reversible_transport" reversible="true">
18320 <notes>
18321 <html:p>GENE_ASSOCIATION: </html:p>
18322 <html:p>PROTEIN_ASSOCIATION: </html:p>
18323 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
18324 <html:p>PROTEIN_CLASS: </html:p>
18325 </notes>
18326 <listOfReactants>
18327 <speciesReference species="M_xan_e" stoichiometry="1.000000"/>
18328 </listOfReactants>
18329 <listOfProducts>
18330 <speciesReference species="M_xan_c" stoichiometry="1.000000"/>
18331 </listOfProducts>
18332 </reaction>
18333 <reaction id="R_XANt2" name="R_xanthine_transport_in_via_proton_symport" reversible="false">
18334 <notes>
18335 <html:p>GENE_ASSOCIATION: b3654</html:p>
18336 <html:p>PROTEIN_ASSOCIATION: YicE</html:p>
18337 <html:p>SUBSYSTEM: S_Putative_Transporters</html:p>
18338 <html:p>PROTEIN_CLASS: </html:p>
18339 </notes>
18340 <listOfReactants>
18341 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
18342 <speciesReference species="M_xan_e" stoichiometry="1.000000"/>
18343 </listOfReactants>
18344 <listOfProducts>
18345 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
18346 <speciesReference species="M_xan_c" stoichiometry="1.000000"/>
18347 </listOfProducts>
18348 </reaction>
18349 <reaction id="R_XPPT" name="R_xanthine_phosphoribosyltransferase" reversible="false">
18350 <notes>
18351 <html:p>GENE_ASSOCIATION: b0238</html:p>
18352 <html:p>PROTEIN_ASSOCIATION: Gpt</html:p>
18353 <html:p>SUBSYSTEM: S_Nucleotide_Salvage_Pathway</html:p>
18354 <html:p>PROTEIN_CLASS: 2.4.2.22</html:p>
18355 </notes>
18356 <listOfReactants>
18357 <speciesReference species="M_prpp_c" stoichiometry="1.000000"/>
18358 <speciesReference species="M_xan_c" stoichiometry="1.000000"/>
18359 </listOfReactants>
18360 <listOfProducts>
18361 <speciesReference species="M_ppi_c" stoichiometry="1.000000"/>
18362 <speciesReference species="M_xmp_c" stoichiometry="1.000000"/>
18363 </listOfProducts>
18364 </reaction>
18365 <reaction id="R_XTSNt2r" name="R_Xanthosine_transport_via_proton_symport" reversible="true">
18366 <notes>
18367 <html:p>GENE_ASSOCIATION: b2406</html:p>
18368 <html:p>PROTEIN_ASSOCIATION: XapB</html:p>
18369 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
18370 <html:p>PROTEIN_CLASS: </html:p>
18371 </notes>
18372 <listOfReactants>
18373 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
18374 <speciesReference species="M_xtsn_e" stoichiometry="1.000000"/>
18375 </listOfReactants>
18376 <listOfProducts>
18377 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
18378 <speciesReference species="M_xtsn_c" stoichiometry="1.000000"/>
18379 </listOfProducts>
18380 </reaction>
18381 <reaction id="R_XYLI1" name="R_xylose_isomerase" reversible="true">
18382 <notes>
18383 <html:p>GENE_ASSOCIATION: b3565</html:p>
18384 <html:p>PROTEIN_ASSOCIATION: XylA</html:p>
18385 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
18386 <html:p>PROTEIN_CLASS: 5.3.1.5</html:p>
18387 </notes>
18388 <listOfReactants>
18389 <speciesReference species="M_xyl_D_c" stoichiometry="1.000000"/>
18390 </listOfReactants>
18391 <listOfProducts>
18392 <speciesReference species="M_xylu_D_c" stoichiometry="1.000000"/>
18393 </listOfProducts>
18394 </reaction>
18395 <reaction id="R_XYLI2i" name="R_xylose_isomerase" reversible="false">
18396 <notes>
18397 <html:p>GENE_ASSOCIATION: b3565</html:p>
18398 <html:p>PROTEIN_ASSOCIATION: XylA</html:p>
18399 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
18400 <html:p>PROTEIN_CLASS: 5.3.1.5</html:p>
18401 </notes>
18402 <listOfReactants>
18403 <speciesReference species="M_fru_c" stoichiometry="1.000000"/>
18404 </listOfReactants>
18405 <listOfProducts>
18406 <speciesReference species="M_glc_D_c" stoichiometry="1.000000"/>
18407 </listOfProducts>
18408 </reaction>
18409 <reaction id="R_XYLK" name="R_xylulokinase" reversible="false">
18410 <notes>
18411 <html:p>GENE_ASSOCIATION: b3564</html:p>
18412 <html:p>PROTEIN_ASSOCIATION: XylB</html:p>
18413 <html:p>SUBSYSTEM: S_Alternate_Carbon_Metabolism</html:p>
18414 <html:p>PROTEIN_CLASS: 2.7.1.17</html:p>
18415 </notes>
18416 <listOfReactants>
18417 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
18418 <speciesReference species="M_xylu_D_c" stoichiometry="1.000000"/>
18419 </listOfReactants>
18420 <listOfProducts>
18421 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
18422 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
18423 <speciesReference species="M_xu5p_D_c" stoichiometry="1.000000"/>
18424 </listOfProducts>
18425 </reaction>
18426 <reaction id="R_XYLabc" name="R_D_xylose_transport_via_ABC_system" reversible="false">
18427 <notes>
18428 <html:p>GENE_ASSOCIATION: ( b3566 and b3567 and b3568 )</html:p>
18429 <html:p>PROTEIN_ASSOCIATION: ( XylF and XylG and XylH )</html:p>
18430 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
18431 <html:p>PROTEIN_CLASS: </html:p>
18432 </notes>
18433 <listOfReactants>
18434 <speciesReference species="M_atp_c" stoichiometry="1.000000"/>
18435 <speciesReference species="M_h2o_c" stoichiometry="1.000000"/>
18436 <speciesReference species="M_xyl_D_e" stoichiometry="1.000000"/>
18437 </listOfReactants>
18438 <listOfProducts>
18439 <speciesReference species="M_adp_c" stoichiometry="1.000000"/>
18440 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
18441 <speciesReference species="M_pi_c" stoichiometry="1.000000"/>
18442 <speciesReference species="M_xyl_D_c" stoichiometry="1.000000"/>
18443 </listOfProducts>
18444 </reaction>
18445 <reaction id="R_XYLt2" name="R_D_xylose_transport_in_via_proton_symport" reversible="false">
18446 <notes>
18447 <html:p>GENE_ASSOCIATION: b4031</html:p>
18448 <html:p>PROTEIN_ASSOCIATION: XylE</html:p>
18449 <html:p>SUBSYSTEM: S_Transport__Extracellular</html:p>
18450 <html:p>PROTEIN_CLASS: </html:p>
18451 </notes>
18452 <listOfReactants>
18453 <speciesReference species="M_h_e" stoichiometry="1.000000"/>
18454 <speciesReference species="M_xyl_D_e" stoichiometry="1.000000"/>
18455 </listOfReactants>
18456 <listOfProducts>
18457 <speciesReference species="M_h_c" stoichiometry="1.000000"/>
18458 <speciesReference species="M_xyl_D_c" stoichiometry="1.000000"/>
18459 </listOfProducts>
18460 </reaction>
18461 </listOfReactions>
18462 </model>
18463 </sbml>
18464
Attached Files
To refer to attachments on a page, use attachment:filename, as shown below in the list of files. Do NOT use the URL of the [get] link, since this is subject to change and can break easily.- [get | view] (2011-10-20 20:44:35, 835.8 KB) [[attachment:EC_iJR904.xml]]
- [get | view] (2011-10-20 20:44:35, 835.8 KB) [[attachment:EcoliSBML]]
- [get | view] (2011-10-20 20:44:35, 7.0 KB) [[attachment:example1.xml]]
You are not allowed to attach a file to this page.