Diff for "Molecular_Interaction_Maps/StateCombination"

Differences between revisions 1 and 3 (spanning 2 versions)

For Feature : MIMEditor

Summary

A user wants specify a condition that is the combination of two previously specified conditions. The two previous conditions may exist in separate species or within the same molecule.

Step-by-Step User Action

User specifies a species to be combined
User specifies another species to be combined
User specifies that the two species are to be combined
User optionally specifies the evidence for the relationship

Visual Aides

The combination is represented with an arrowless line between the two species:

attachment:statecombination1_061115_dwk.png

State combinations can occur intramolecularly, for example, two different modifications on two different residues within the same molecule might be required for a specific activity. In the example below a phosphorylation reaction and an acetylation reaction are both required for stimulation:

attachment:statecombination2_061115_dwk.png

Requirements for Cytoscape

TBD

Importance

This is of moderate importance. A situation in which a reaction is contingent upon several requirements is common in biology. Examples include enzymes that need to be modified on several residues (phoshphorylation, acetylation) in order to catalyze specific reactions, or molecules that need to bind several other molecues in an unspecified order to participate in a process.

== Variations ==

TBD Add an example in which the same molcule is involved in both states

Other Examples

Comments

Shared MimEditorUseCaseComments

PageComment2

Molecular_Interaction_Maps/StateCombination (last edited 2009-02-12 01:03:38 by localhost)

-  ← Revision 1 as of 2006-11-15 21:35:47 →
  Size: 3037
  Editor: lfrq80
  Comment:
+  ← Revision 3 as of 2006-11-15 22:38:20 →
  Size: 3347
  Editor: lfrq80
  Comment:
-Deletions are marked like this.
+Additions are marked like this.
 Line 21:
-A user wants specify that two species are both required for a reaction, but without being bound.
+A user wants specify a condition that is the combination of two previously specified conditions. The two previous conditions may exist in separate species  or within the same molecule.
 Line 36:
+attachment:statecombination1_061115_dwk.png
-Line 37:
+Line 39:
+attachment:statecombination2_061115_dwk.png
-Line 47:
+Line 51:
-A situation in which a reaction is contingent upon several requirements is common in biology.  Examples include enzymmes that need to be modified on several  residues (phoshphorylation, acetylation) in order to catalyze specific reactions, or molecules that need to bind several other molecues in an unspecified order to participate in a process.
+This is of moderate importance.  A situation in which a reaction is contingent upon several requirements is common in biology.  Examples include enzymes that need to be modified on several  residues (phoshphorylation, acetylation) in order to catalyze specific reactions, or molecules that need to bind several other molecues in an unspecified order to participate in a process.  



== Variations == 



TBD Add an example in which the same molcule is involved in both states