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DomainGraph: Visual Analysis of the Effects of Alternative Splicing on Protein and Domain Interaction Networks
Dorothea Emig1, Melissa S. Cline2, Thomas Lengauer1, and Mario Albrecht1
1 Department of Computational Biology and Applied Algorithmics, Max Planck Institute for Informatics, Campus E1.4, 66123 Saarbrücken, Germany
2 Department of Molecular Cell and Developmental Biology, University of California, Santa Cruz, CA 95064, USA
Biological Use Case: Visualize the domain interactions that actually form a protein interaction network. Integrate exon expression data to visualize occurrences of alternative splicing events and the impact on the interactions.
Recipe
Cytoscape version: 2.5, 2.6
Plugins to Load: DomainGraph (http://domaingraph.bioinf.mpi-inf.mpg.de)
GUI steps:
Describe each step (story), the GUI action to take, and probable remarks
Story |
Action |
Remarks |
Create local database |
Plugins -> DomainGraph -> Create Database |
has to be done the first time, the db is stored locally in the Cytoscape plugins directory |
Data / Session Files: Attach (preferably) a session file or else the data files used in the workflow
Presentation: Attach your presentation
Webstart: Attach a webstart
Video: Attach a video link