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 ''2 Department of Molecular Cell and Developmental Biology, University of California, Santa Cruz, CA 95064, USA''' '''''
''2 Department of Molecular Cell and Developmental Biology, University of California, Santa Cruz, CA 95064, USA''' '''''

DomainGraph: Visual Analysis of the Effects of Alternative Splicing on Protein and Domain Interaction Networks

Dorothea Emig1, Melissa S. Cline2, Thomas Lengauer1, and Mario Albrecht1

1 Department of Computational Biology and Applied Algorithmics, Max Planck Institute for Informatics, Campus E1.4, 66123 Saarbrücken, Germany

2 Department of Molecular Cell and Developmental Biology, University of California, Santa Cruz, CA 95064, USA

Biological Use Case: Visualize the domain interactions that actually form a protein interaction network. Integrate exon expression data to visualize occurrences of alternative splicing events and the impact on the interactions.

Recipe

Cytoscape version: 2.5, 2.6

Plugins to Load: DomainGraph (http://domaingraph.bioinf.mpi-inf.mpg.de)

GUI steps:

Describe each step (story), the GUI action to take, and probable remarks

Story

Action

Remarks

Data / Session Files: Attach (preferably) a session file or else the data files used in the workflow

Presentation: Attach your presentation

Webstart: Attach a webstart

Video: Attach a video link

DomainGraphRecipe (last edited 2009-02-12 01:03:01 by localhost)

Funding for Cytoscape is provided by a federal grant from the U.S. National Institute of General Medical Sciences (NIGMS) of the Na tional Institutes of Health (NIH) under award number GM070743-01. Corporate funding is provided through a contract from Unilever PLC.

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